Total number of protein in "GO:0001947" GO term: 65
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AHI1-201 | AHI1 | Q8N157 | Jouberin | chr6 | GO:0001947 | Not Cancer Driver | No | 74 | 0.0618729096989966 | 503 | 29 | 0.0242474916387959 | 6 |
| APLNR-202 | APLNR | P35414 | Apelin receptor | chr11 | GO:0001947 | Not Cancer Driver | No | 76 | 0.2 | 29 | 7 | 0.0184210526315789 | 0 |
| ARL13B-203 | ARL13B | Q3SXY8 | ADP-ribosylation factor-like protein 13B | chr3 | GO:0001947 | Not Cancer Driver | No | 48 | 0.1121495327102803 | 251 | 34 | 0.0794392523364486 | 3 |
| ASB2-203 | ASB2 | Q96Q27 | Ankyrin repeat and SOCS box protein 2 | chr14 | GO:0001947 | Not Cancer Driver | No | 66 | 0.1039370078740157 | 167 | 16 | 0.0251968503937007 | 0 |
| BBS5-201 | BBS5 | Q8N3I7 | Bardet-Biedl syndrome 5 protein | chr2 | GO:0001947 | Not Cancer Driver | No | 24 | 0.0703812316715542 | 20 | 0 | 0.0 | 2 |
| BBS7-201 | BBS7 | Q8IWZ6 | Bardet-Biedl syndrome 7 protein | chr4 | GO:0001947 | Not Cancer Driver | No | 69 | 0.0965034965034965 | 56 | 4 | 0.0055944055944055 | 4 |
| C2CD3-202 | C2CD3 | Q4AC94 | C2 domain-containing protein 3 | chr11 | GO:0001947 | Not Cancer Driver | No | 183 | 0.0777730556736081 | 1105 | 74 | 0.0314492137696557 | 1 |
| CCDC103-204 | CCDC103 | Q8IW40 | Coiled-coil domain-containing protein 103 | chr17 | GO:0001947 | Not Cancer Driver | No | 12 | 0.0495867768595041 | 78 | 6 | 0.024793388429752 | 0 |
| CCDC39-202 | CCDC39 | Q9UFE4 | Coiled-coil domain-containing protein 39 | chr3 | GO:0001947 | Not Cancer Driver | No | 156 | 0.1657810839532412 | 498 | 64 | 0.0680127523910733 | 0 |
| CCDC40-204 | CCDC40 | Q4G0X9 | Coiled-coil domain-containing protein 40 | chr17 | GO:0001947 | Not Cancer Driver | No | 144 | 0.1260945709281961 | 675 | 90 | 0.0788091068301225 | 0 |
| CITED2-201 | CITED2 | Q99967 | Cbp/p300-interacting transactivator 2 | chr6 | GO:0001947 | Not Cancer Driver | No | 22 | 0.0814814814814814 | 232 | 19 | 0.0703703703703703 | 0 |
| CLUAP1-212 | CLUAP1 | Q96AJ1 | Clusterin-associated protein 1 | chr16 | GO:0001947 | Not Cancer Driver | No | 32 | 0.0774818401937046 | 203 | 17 | 0.0411622276029055 | 0 |
| DLL1-201 | DLL1 | O00548 | Delta-like protein 1 | chr6 | GO:0001947 | Not Cancer Driver | No | 81 | 0.1120331950207468 | 145 | 15 | 0.0207468879668049 | 1 |
| DNAAF1-201 | DNAAF1 | Q8NEP3 | Dynein axonemal assembly factor 1 | chr16 | GO:0001947 | Not Cancer Driver | No | 81 | 0.1117241379310344 | 525 | 60 | 0.0827586206896551 | 1 |
| DVL1-201 | DVL1 | O14640 | Segment polarity protein dishevelled homolog DVL-1 | chr1 | GO:0001947 | Not Cancer Driver | No | 42 | 0.0604316546762589 | 434 | 16 | 0.0230215827338129 | 0 |
| DVL2-201 | DVL2 | O14641 | Segment polarity protein dishevelled homolog DVL-2 | chr17 | GO:0001947 | Not Cancer Driver | No | 72 | 0.0978260869565217 | 515 | 52 | 0.0706521739130434 | 0 |
| ENG-202 | ENG | P17813 | Endoglin | chr9 | GO:0001947 | Not Cancer Driver | No | 47 | 0.0714285714285714 | 114 | 11 | 0.0167173252279635 | 29 |
| FGF8-202 | FGF8 | P55075 | Fibroblast growth factor 8 | chr10 | GO:0001947 | Not Cancer Driver | No | 27 | 0.1158798283261802 | 79 | 8 | 0.0343347639484978 | 6 |
| FOLR1-202 | FOLR1 | P15328 | Folate receptor alpha | chr11 | GO:0001947 | Not Cancer Driver | No | 24 | 0.0933852140077821 | 13 | 1 | 0.0038910505836575 | 0 |
| FOXH1-201 | FOXH1 | O75593 | Forkhead box protein H1 | chr8 | GO:0001947 | Not Cancer Driver | No | 38 | 0.1041095890410958 | 217 | 19 | 0.0520547945205479 | 0 |
| FOXN4-201 | FOXN4 | Q96NZ1 | Forkhead box protein N4 | chr12 | GO:0001947 | Not Cancer Driver | No | 43 | 0.0831721470019342 | 379 | 27 | 0.0522243713733075 | 0 |
| GATA4-201 | GATA4 | P43694 | Transcription factor GATA-4 | chr8 | GO:0001947 | Not Cancer Driver | No | 34 | 0.0769230769230769 | 297 | 23 | 0.0520361990950226 | 21 |
| GJA1-201 | GJA1 | P17302 | Gap junction alpha-1 protein | chr6 | GO:0001947 | Not Cancer Driver | No | 62 | 0.1623036649214659 | 111 | 20 | 0.0523560209424083 | 43 |
| HAND1-201 | HAND1 | O96004 | Heart- and neural crest derivatives-expressed protein 1 | chr5 | GO:0001947 | Not Cancer Driver | No | 24 | 0.1116279069767441 | 167 | 19 | 0.0883720930232558 | 0 |
| HAND2-201 | HAND2 | P61296 | Heart- and neural crest derivatives-expressed protein 2 | chr4 | GO:0001947 | Not Cancer Driver | No | 39 | 0.1797235023041474 | 124 | 24 | 0.1105990783410138 | 0 |
| HIF1A-202 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:0001947 | Census | Yes | 54 | 0.0653753026634382 | 436 | 28 | 0.0338983050847457 | 0 |
| IFT172-201 | IFT172 | Q9UG01 | Intraflagellar transport protein 172 homolog | chr2 | GO:0001947 | Not Cancer Driver | No | 154 | 0.0880503144654088 | 96 | 4 | 0.0022870211549456 | 8 |
| IFT52-201 | IFT52 | Q9Y366 | Intraflagellar transport protein 52 homolog | chr20 | GO:0001947 | Not Cancer Driver | No | 45 | 0.102974828375286 | 56 | 6 | 0.0137299771167048 | 1 |
| IFT57-201 | IFT57 | Q9NWB7 | Intraflagellar transport protein 57 homolog | chr3 | GO:0001947 | Not Cancer Driver | No | 36 | 0.0839160839160839 | 219 | 18 | 0.0419580419580419 | 0 |
| IHH-201 | IHH | Q14623 | Indian hedgehog protein | chr2 | GO:0001947 | Not Cancer Driver | No | 50 | 0.121654501216545 | 111 | 14 | 0.0340632603406326 | 5 |
| LBX1-201 | LBX1 | P52954 | Transcription factor LBX1 | chr10 | GO:0001947 | Not Cancer Driver | No | 20 | 0.0711743772241993 | 181 | 14 | 0.0498220640569395 | 0 |
| MEF2C-209 | MEF2C | Q06413 | Myocyte-specific enhancer factor 2C | chr5 | GO:0001947 | Not Cancer Driver | No | 54 | 0.1141649048625792 | 408 | 51 | 0.1078224101479915 | 2 |
| MESP1-201 | MESP1 | Q9BRJ9 | Mesoderm posterior protein 1 | chr15 | GO:0001947 | Not Cancer Driver | No | 8 | 0.0298507462686567 | 250 | 7 | 0.0261194029850746 | 0 |
| MIB1-201 | MIB1 | Q86YT6 | E3 ubiquitin-protein ligase MIB1 | chr18 | GO:0001947 | Not Cancer Driver | No | 96 | 0.0954274353876739 | 284 | 26 | 0.025844930417495 | 1 |
| MICAL2-234 | MICAL2 | O94851 | [F-actin]-monooxygenase MICAL2 | chr11 | GO:0001947 | Not Cancer Driver | No | 224 | 0.114460909555442 | 1205 | 131 | 0.0669391926417986 | 0 |
| MKKS-201 | MKKS | Q9NPJ1 | Molecular chaperone MKKS | chr20 | GO:0001947 | Not Cancer Driver | No | 35 | 0.0614035087719298 | 7 | 0 | 0.0 | 22 |
| NDRG4-255 | NDRG4 | Q9ULP0 | Protein NDRG4 | chr16 | GO:0001947 | Not Cancer Driver | No | 34 | 0.096590909090909 | 90 | 10 | 0.0284090909090909 | 0 |
| NKX2-5-201 | NKX2-5 | P52952 | Homeobox protein Nkx-2.5 | chr5 | GO:0001947 | Not Cancer Driver | No | 43 | 0.132716049382716 | 182 | 19 | 0.0586419753086419 | 52 |
| NODAL-201 | NODAL | Q96S42 | Nodal homolog | chr10 | GO:0001947 | Not Cancer Driver | No | 34 | 0.0979827089337175 | 34 | 9 | 0.0259365994236311 | 4 |
| NOTCH1-204 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | GO:0001947 | Census, Compendium | Yes | 312 | 0.1221135029354207 | 690 | 71 | 0.0277886497064579 | 3 |
| NOTCH2-201 | NOTCH2 | Q04721 | Neurogenic locus notch homolog protein 2 | chr1 | GO:0001947 | Census, Compendium | Yes | 191 | 0.0772966410360178 | 631 | 61 | 0.0246863617968433 | 1 |
| NOTO-201 | NOTO | A8MTQ0 | Homeobox protein notochord | chr2 | GO:0001947 | Not Cancer Driver | No | 10 | 0.0398406374501992 | 116 | 4 | 0.0159362549800796 | 0 |
| NPHP3-201 | NPHP3 | Q7Z494 | Nephrocystin-3 | chr3 | GO:0001947 | Not Cancer Driver | No | 89 | 0.0669172932330827 | 250 | 24 | 0.0180451127819548 | 7 |
| OVOL2-201 | OVOL2 | Q9BRP0 | Transcription factor Ovo-like 2 | chr20 | GO:0001947 | Not Cancer Driver | No | 28 | 0.1018181818181818 | 141 | 5 | 0.0181818181818181 | 0 |
| PKD2-201 | PKD2 | Q13563 | Polycystin-2 | chr4 | GO:0001947 | Not Cancer Driver | No | 88 | 0.0909090909090909 | 376 | 30 | 0.03099173553719 | 9 |
| PSEN1-201 | PSEN1 | P49768 | Presenilin-1 | chr14 | GO:0001947 | Not Cancer Driver | No | 43 | 0.0920770877944325 | 134 | 18 | 0.038543897216274 | 69 |
| SETDB2-202 | SETDB2 | Q96T68 | Histone-lysine N-methyltransferase SETDB2 | chr13 | GO:0001947 | Not Cancer Driver | No | 51 | 0.0709318497913769 | 255 | 20 | 0.0278164116828929 | 0 |
| SHH-201 | SHH | Q15465 | Sonic hedgehog protein | chr7 | GO:0001947 | Not Cancer Driver | No | 36 | 0.0779220779220779 | 139 | 11 | 0.0238095238095238 | 69 |
| SMAD3-201 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0001947 | Census, Compendium | Yes | 80 | 0.188235294117647 | 113 | 15 | 0.0352941176470588 | 5 |
| SMO-201 | SMO | Q99835 | Protein smoothened | chr7 | GO:0001947 | Census, Compendium | Yes | 88 | 0.1118170266836086 | 242 | 20 | 0.025412960609911 | 1 |
| SOX17-201 | SOX17 | Q9H6I2 | Transcription factor SOX-17 | chr8 | GO:0001947 | Compendium | Yes | 64 | 0.1545893719806763 | 379 | 45 | 0.108695652173913 | 2 |
| SOX18-201 | SOX18 | P35713 | Transcription factor SOX-18 | chr20 | GO:0001947 | Not Cancer Driver | No | 8 | 0.0208333333333333 | 321 | 8 | 0.0208333333333333 | 2 |
| SRF-201 | SRF | P11831 | Serum response factor | chr6 | GO:0001947 | Not Cancer Driver | No | 30 | 0.0590551181102362 | 443 | 29 | 0.0570866141732283 | 0 |
| STIL-202 | STIL | Q15468 | SCL-interrupting locus protein | chr1 | GO:0001947 | Census, Compendium | Yes | 106 | 0.0823620823620823 | 735 | 64 | 0.0497280497280497 | 1 |
| SUFU-202 | SUFU | Q9UMX1 | Suppressor of fused homolog | chr10 | GO:0001947 | Census | Yes | 48 | 0.0991735537190082 | 200 | 15 | 0.03099173553719 | 2 |
| TBX2-201 | TBX2 | Q13207 | T-box transcription factor TBX2 | chr17 | GO:0001947 | Not Cancer Driver | No | 64 | 0.0898876404494382 | 401 | 30 | 0.0421348314606741 | 1 |
| TBX20-201 | TBX20 | Q9UMR3 | T-box transcription factor TBX20 | chr7 | GO:0001947 | Not Cancer Driver | No | 95 | 0.2125279642058165 | 201 | 43 | 0.0961968680089485 | 2 |
| TBX3-201 | TBX3 | O15119 | T-box transcription factor TBX3 | chr12 | GO:0001947 | Census, Compendium | Yes | 102 | 0.1372812920592193 | 353 | 52 | 0.0699865410497981 | 2 |
| TBX6-202 | TBX6 | O95947 | T-box transcription factor TBX6 | chr16 | GO:0001947 | Not Cancer Driver | No | 34 | 0.0779816513761468 | 253 | 17 | 0.0389908256880734 | 0 |
| TGFBR2-201 | TGFBR2 | P37173 | TGF-beta receptor type-2 | chr3 | GO:0001947 | Census, Compendium | Yes | 93 | 0.164021164021164 | 61 | 15 | 0.0264550264550264 | 21 |
| TMED2-201 | TMED2 | Q15363 | Transmembrane emp24 domain-containing protein 2 | chr12 | GO:0001947 | Not Cancer Driver | No | 16 | 0.0796019900497512 | 25 | 2 | 0.0099502487562189 | 0 |
| VANGL2-201 | VANGL2 | Q9ULK5 | Vang-like protein 2 | chr1 | GO:0001947 | Not Cancer Driver | No | 79 | 0.1516314779270633 | 150 | 13 | 0.0249520153550863 | 3 |
| WNT3A-201 | WNT3A | P56704 | Protein Wnt-3a | chr1 | GO:0001947 | Not Cancer Driver | No | 60 | 0.1704545454545454 | 37 | 2 | 0.0056818181818181 | 0 |
| WNT5A-201 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0001947 | Not Cancer Driver | No | 42 | 0.1105263157894736 | 0 | 0 | 0.0 | 2 |
| ZIC3-201 | ZIC3 | O60481 | Zinc finger protein ZIC 3 | chrX | GO:0001947 | Not Cancer Driver | No | 69 | 0.1477516059957173 | 327 | 47 | 0.1006423982869379 | 10 |