Total number of protein in "GO:0002039" GO term: 66
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ANKRD1-201 | ANKRD1 | Q15327 | Ankyrin repeat domain-containing protein 1 | chr10 | GO:0002039 | Not Cancer Driver | No | 30 | 0.0940438871473354 | 83 | 7 | 0.0219435736677116 | 0 |
| AXIN1-201 | AXIN1 | O15169 | Axin-1 | chr16 | GO:0002039 | Census, Compendium | Yes | 91 | 0.105568445475638 | 623 | 69 | 0.0800464037122969 | 4 |
| BLM-201 | BLM | P54132 | RecQ-like DNA helicase BLM | chr15 | GO:0002039 | Census | Yes | 112 | 0.0790402258292166 | 671 | 53 | 0.0374029640084686 | 9 |
| BRCA1-203 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | GO:0002039 | Census, Compendium | Yes | 167 | 0.0896403650026838 | 1466 | 127 | 0.0681696188942565 | 34 |
| BRD4-213 | BRD4 | O60885 | Bromodomain-containing protein 4 | chr19 | GO:0002039 | Census, Compendium | Yes | 143 | 0.1049926578560939 | 1184 | 132 | 0.0969162995594713 | 0 |
| BRD7-201 | BRD7 | Q9NPI1 | Bromodomain-containing protein 7 | chr16 | GO:0002039 | Compendium | Yes | 58 | 0.0890937019969278 | 485 | 33 | 0.0506912442396313 | 0 |
| CDK5-204 | CDK5 | Q00535 | Cyclin-dependent kinase 5 | chr7 | GO:0002039 | Not Cancer Driver | No | 38 | 0.1301369863013698 | 5 | 0 | 0.0 | 0 |
| CDKN2AIP-203 | CDKN2AIP | Q9NXV6 | CDKN2A-interacting protein | chr4 | GO:0002039 | Not Cancer Driver | No | 18 | 0.0310344827586206 | 352 | 15 | 0.0258620689655172 | 0 |
| CHD8-224 | CHD8 | Q9HCK8 | Chromodomain-helicase-DNA-binding protein 8 | chr14 | GO:0002039 | Not Cancer Driver | No | 234 | 0.0906625339015885 | 1413 | 107 | 0.0414567996900426 | 0 |
| CREBBP-201 | CREBBP | Q92793 | CREB-binding protein | chr16 | GO:0002039 | Census, Compendium | Yes | 217 | 0.0888615888615888 | 1801 | 91 | 0.0372645372645372 | 30 |
| DAXX-202 | DAXX | Q9UER7 | Death domain-associated protein 6 | chr6 | GO:0002039 | Census, Compendium | Yes | 79 | 0.1067567567567567 | 549 | 57 | 0.077027027027027 | 0 |
| DAZAP2-201 | DAZAP2 | Q15038 | DAZ-associated protein 2 | chr12 | GO:0002039 | Not Cancer Driver | No | 11 | 0.0654761904761904 | 68 | 6 | 0.0357142857142857 | 0 |
| DUSP26-201 | DUSP26 | Q9BV47 | Dual specificity protein phosphatase 26 | chr8 | GO:0002039 | Not Cancer Driver | No | 45 | 0.2132701421800948 | 14 | 4 | 0.0189573459715639 | 0 |
| EHMT1-203 | EHMT1 | Q9H9B1 | Histone-lysine N-methyltransferase EHMT1 | chr9 | GO:0002039 | Not Cancer Driver | No | 128 | 0.098613251155624 | 705 | 65 | 0.0500770416024653 | 1 |
| EHMT2-203 | EHMT2 | Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | chr6 | GO:0002039 | Not Cancer Driver | No | 103 | 0.0851239669421487 | 585 | 49 | 0.040495867768595 | 0 |
| EP300-201 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | GO:0002039 | Census, Compendium | Yes | 203 | 0.084092792046396 | 1792 | 84 | 0.0347970173985087 | 1 |
| GATA1-202 | GATA1 | P15976 | Erythroid transcription factor | chrX | GO:0002039 | Census, Compendium | Yes | 57 | 0.1380145278450363 | 242 | 34 | 0.0823244552058111 | 5 |
| GSK3B-201 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | GO:0002039 | Not Cancer Driver | No | 34 | 0.0809523809523809 | 148 | 6 | 0.0142857142857142 | 0 |
| HDAC1-201 | HDAC1 | Q13547 | Histone deacetylase 1 | chr1 | GO:0002039 | Not Cancer Driver | No | 30 | 0.0622406639004149 | 135 | 5 | 0.0103734439834024 | 0 |
| HIF1A-202 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:0002039 | Census | Yes | 54 | 0.0653753026634382 | 436 | 28 | 0.0338983050847457 | 0 |
| HSPD1-202 | HSPD1 | P10809 | 60 kDa heat shock protein, mitochondrial | chr2 | GO:0002039 | Not Cancer Driver | No | 45 | 0.0785340314136125 | 83 | 1 | 0.0017452006980802 | 2 |
| HTT-201 | HTT | P42858 | Huntingtin | chr4 | GO:0002039 | Not Cancer Driver | No | 261 | 0.0830681094844048 | 668 | 51 | 0.0162316995544239 | 2 |
| KDM1A-201 | KDM1A | O60341 | Lysine-specific histone demethylase 1A | chr1 | GO:0002039 | Not Cancer Driver | No | 48 | 0.056338028169014 | 291 | 21 | 0.0246478873239436 | 3 |
| KDM8-201 | KDM8 | Q8N371 | Bifunctional peptidase and arginyl-hydroxylase JMJD5 | chr16 | GO:0002039 | Not Cancer Driver | No | 32 | 0.0769230769230769 | 29 | 6 | 0.0144230769230769 | 0 |
| MAPKAPK5-207 | MAPKAPK5 | Q8IW41 | MAP kinase-activated protein kinase 5 | chr12 | GO:0002039 | Not Cancer Driver | No | 38 | 0.080338266384778 | 101 | 6 | 0.0126849894291754 | 0 |
| MDM2-224 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | GO:0002039 | Census, Compendium | Yes | 39 | 0.0794297352342158 | 298 | 24 | 0.0488798370672097 | 0 |
| MSX1-201 | MSX1 | P28360 | Homeobox protein MSX-1 | chr4 | GO:0002039 | Not Cancer Driver | No | 32 | 0.1056105610561056 | 199 | 12 | 0.0396039603960396 | 7 |
| MUL1-201 | MUL1 | Q969V5 | Mitochondrial ubiquitin ligase activator of NFKB 1 | chr1 | GO:0002039 | Not Cancer Driver | No | 29 | 0.0823863636363636 | 16 | 2 | 0.0056818181818181 | 0 |
| NOP53-201 | NOP53 | Q9NZM5 | Ribosome biogenesis protein NOP53 | chr19 | GO:0002039 | Not Cancer Driver | No | 36 | 0.0753138075313807 | 399 | 26 | 0.0543933054393305 | 0 |
| NTRK3-217 | NTRK3 | Q16288 | NT-3 growth factor receptor | chr15 | GO:0002039 | Census, Compendium | Yes | 214 | 0.2550655542312277 | 56 | 15 | 0.0178784266984505 | 3 |
| NUAK1-201 | NUAK1 | O60285 | NUAK family SNF1-like kinase 1 | chr12 | GO:0002039 | Not Cancer Driver | No | 115 | 0.1739788199697428 | 358 | 67 | 0.1013615733736762 | 0 |
| PLK3-201 | PLK3 | Q9H4B4 | Serine/threonine-protein kinase PLK3 | chr1 | GO:0002039 | Not Cancer Driver | No | 55 | 0.0851393188854489 | 203 | 11 | 0.0170278637770897 | 0 |
| POU4F2-201 | POU4F2 | Q12837 | POU domain, class 4, transcription factor 2 | chr4 | GO:0002039 | Not Cancer Driver | No | 96 | 0.2347188264058679 | 311 | 64 | 0.1564792176039119 | 0 |
| PPP1R13B-201 | PPP1R13B | Q96KQ4 | Apoptosis-stimulating of p53 protein 1 | chr14 | GO:0002039 | Not Cancer Driver | No | 87 | 0.0798165137614679 | 821 | 70 | 0.0642201834862385 | 0 |
| PRMT5-202 | PRMT5 | O14744 | Protein arginine N-methyltransferase 5 | chr14 | GO:0002039 | Not Cancer Driver | No | 62 | 0.097331240188383 | 72 | 3 | 0.0047095761381475 | 0 |
| PSME3-210 | PSME3 | P61289 | Proteasome activator complex subunit 3 | chr17 | GO:0002039 | Not Cancer Driver | No | 16 | 0.0629921259842519 | 25 | 5 | 0.0196850393700787 | 0 |
| PTTG1IP-201 | PTTG1IP | P53801 | Pituitary tumor-transforming gene 1 protein-interacting protein | chr21 | GO:0002039 | Not Cancer Driver | No | 16 | 0.0888888888888888 | 30 | 6 | 0.0333333333333333 | 0 |
| RCHY1-201 | RCHY1 | Q96PM5 | RING finger and CHY zinc finger domain-containing protein 1 | chr4 | GO:0002039 | Not Cancer Driver | No | 18 | 0.0689655172413793 | 23 | 0 | 0.0 | 0 |
| RFFL-202 | RFFL | Q8WZ73 | E3 ubiquitin-protein ligase rififylin | chr17 | GO:0002039 | Not Cancer Driver | No | 39 | 0.1074380165289256 | 151 | 17 | 0.046831955922865 | 0 |
| RFWD3-201 | RFWD3 | Q6PCD5 | E3 ubiquitin-protein ligase RFWD3 | chr16 | GO:0002039 | Census | Yes | 59 | 0.0762273901808785 | 319 | 26 | 0.0335917312661498 | 1 |
| RNF125-201 | RNF125 | Q96EQ8 | E3 ubiquitin-protein ligase RNF125 | chr18 | GO:0002039 | Not Cancer Driver | No | 23 | 0.0991379310344827 | 27 | 1 | 0.0043103448275862 | 3 |
| RNF20-202 | RNF20 | Q5VTR2 | E3 ubiquitin-protein ligase BRE1A | chr9 | GO:0002039 | Not Cancer Driver | No | 83 | 0.0851282051282051 | 563 | 43 | 0.0441025641025641 | 0 |
| RNF34-201 | RNF34 | Q969K3 | E3 ubiquitin-protein ligase RNF34 | chr12 | GO:0002039 | Not Cancer Driver | No | 17 | 0.0456989247311828 | 112 | 4 | 0.010752688172043 | 0 |
| SETD7-201 | SETD7 | Q8WTS6 | Histone-lysine N-methyltransferase SETD7 | chr4 | GO:0002039 | Not Cancer Driver | No | 26 | 0.0710382513661202 | 106 | 5 | 0.0136612021857923 | 0 |
| SIRT1-201 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0002039 | Not Cancer Driver | No | 43 | 0.0575635876840696 | 435 | 19 | 0.0254350736278447 | 0 |
| SMARCA4-201 | SMARCA4 | P51532 | Transcription activator BRG1 | chr19 | GO:0002039 | Census, Compendium | Yes | 300 | 0.1821493624772313 | 1078 | 163 | 0.0989678202792957 | 5 |
| SMARCB1-213 | SMARCB1 | Q12824 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 | chr22 | GO:0002039 | Census, Compendium | Yes | 55 | 0.1428571428571428 | 141 | 26 | 0.0675324675324675 | 3 |
| SMYD2-201 | SMYD2 | Q9NRG4 | N-lysine methyltransferase SMYD2 | chr1 | GO:0002039 | Not Cancer Driver | No | 27 | 0.0623556581986143 | 12 | 0 | 0.0 | 0 |
| STK11-201 | STK11 | Q15831 | Serine/threonine-protein kinase STK11 | chr19 | GO:0002039 | Census, Compendium | Yes | 63 | 0.1454965357967667 | 135 | 12 | 0.0277136258660508 | 9 |
| TAF1-204 | TAF1 | P21675 | Transcription initiation factor TFIID subunit 1 | chrX | GO:0002039 | Not Cancer Driver | No | 278 | 0.1484249866524292 | 1174 | 156 | 0.0832888414308595 | 5 |
| TAF3-201 | TAF3 | Q5VWG9 | Transcription initiation factor TFIID subunit 3 | chr10 | GO:0002039 | Not Cancer Driver | No | 85 | 0.0914962325080731 | 753 | 71 | 0.0764262648008611 | 0 |
| TAF9-201 | TAF9 | Q16594 | Transcription initiation factor TFIID subunit 9 | chr5 | GO:0002039 | Not Cancer Driver | No | 19 | 0.0719696969696969 | 203 | 14 | 0.053030303030303 | 0 |
| TEP1-201 | TEP1 | Q99973 | Telomerase protein component 1 | chr14 | GO:0002039 | Not Cancer Driver | No | 251 | 0.0955462504758279 | 398 | 52 | 0.0197944423296536 | 0 |
| TP53-201 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0002039 | Census, Compendium | Yes | 2742 | 6.977099236641221 | 282 | 1364 | 3.470737913486005 | 60 |
| TP53BP1-201 | TP53BP1 | Q12888 | TP53-binding protein 1 | chr15 | GO:0002039 | Not Cancer Driver | No | 159 | 0.0806288032454361 | 1638 | 131 | 0.0664300202839756 | 0 |
| TP53BP2-201 | TP53BP2 | Q13625 | Apoptosis-stimulating of p53 protein 2 | chr1 | GO:0002039 | Not Cancer Driver | No | 106 | 0.0934744268077601 | 866 | 83 | 0.0731922398589065 | 0 |
| TP53RK-202 | TP53RK | Q96S44 | EKC/KEOPS complex subunit TP53RK | chr20 | GO:0002039 | Not Cancer Driver | No | 12 | 0.0474308300395256 | 53 | 1 | 0.0039525691699604 | 3 |
| TP63-201 | TP63 | Q9H3D4 | Tumor protein 63 | chr3 | GO:0002039 | Census, Compendium | Yes | 198 | 0.2911764705882353 | 398 | 120 | 0.1764705882352941 | 21 |
| TP73-208 | TP73 | O15350 | Tumor protein p73 | chr1 | GO:0002039 | Not Cancer Driver | No | 67 | 0.1053459119496855 | 446 | 45 | 0.070754716981132 | 0 |
| TRIAP1-202 | TRIAP1 | O43715 | TP53-regulated inhibitor of apoptosis 1 | chr12 | GO:0002039 | Not Cancer Driver | No | 8 | 0.1052631578947368 | 20 | 1 | 0.0131578947368421 | 0 |
| TRIM24-201 | TRIM24 | O15164 | Transcription intermediary factor 1-alpha | chr7 | GO:0002039 | Census, Compendium | Yes | 90 | 0.0857142857142857 | 537 | 45 | 0.0428571428571428 | 0 |
| TRIM29-201 | TRIM29 | Q14134 | Tripartite motif-containing protein 29 | chr11 | GO:0002039 | Not Cancer Driver | No | 97 | 0.1649659863945578 | 352 | 59 | 0.1003401360544217 | 0 |
| USP10-201 | USP10 | Q14694 | Ubiquitin carboxyl-terminal hydrolase 10 | chr16 | GO:0002039 | Not Cancer Driver | No | 65 | 0.081453634085213 | 423 | 34 | 0.0426065162907268 | 0 |
| USP7-201 | USP7 | Q93009 | Ubiquitin carboxyl-terminal hydrolase 7 | chr16 | GO:0002039 | Not Cancer Driver | No | 135 | 0.1225045372050816 | 215 | 34 | 0.0308529945553539 | 7 |
| ZNF385A-201 | ZNF385A | Q96PM9 | Zinc finger protein 385A | chr12 | GO:0002039 | Not Cancer Driver | No | 29 | 0.0751295336787564 | 312 | 25 | 0.0647668393782383 | 0 |
| ZNF385B-204 | ZNF385B | Q569K4 | Zinc finger protein 385B | chr2 | GO:0002039 | Not Cancer Driver | No | 72 | 0.1481481481481481 | 334 | 44 | 0.0905349794238683 | 0 |