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Total number of protein in "GO:0002931" GO term:  64

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABRAXAS2-201 ABRAXAS2 Q15018 BRISC complex subunit Abraxas 2 chr10 GO:0002931 Not Cancer Driver No 34 0.0819277108433735 207 20 0.0481927710843373 0
AIFM1-201 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX GO:0002931 Not Cancer Driver No 61 0.099510603588907 166 20 0.032626427406199 10
AQP3-201 AQP3 Q92482 Aquaporin-3 chr9 GO:0002931 Not Cancer Driver No 25 0.0856164383561643 12 0 0.0 0
ARID1B-203 ARID1B Q8NFD5 AT-rich interactive domain-containing protein 1B chr6 GO:0002931 Census, Compendium Yes 202 0.0871065114273393 1891 150 0.0646830530401035 2
BCL2-201 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0002931 Census, Compendium Yes 21 0.0878661087866108 73 5 0.0209205020920502 0
BCL2L2-201 BCL2L2 Q92843 Bcl-2-like protein 2 chr14 GO:0002931 Not Cancer Driver No 14 0.0725388601036269 34 2 0.0103626943005181 0
BVES-201 BVES Q8NE79 Blood vessel epicardial substance chr6 GO:0002931 Not Cancer Driver No 46 0.1277777777777777 66 11 0.0305555555555555 1
CAMK2A-201 CAMK2A Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha chr5 GO:0002931 Not Cancer Driver No 62 0.1297071129707113 62 10 0.0209205020920502 7
CASP9-201 CASP9 P55211 Caspase-9 chr1 GO:0002931 Census Yes 26 0.0625 71 7 0.016826923076923 0
CASR-205 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0002931 Not Cancer Driver No 234 0.2170686456400742 189 46 0.0426716141001855 100
CAV1-201 CAV1 Q03135 Caveolin-1 chr7 GO:0002931 Not Cancer Driver No 23 0.1292134831460674 2 0 0.0 0
CAV3-201 CAV3 P56539 Caveolin-3 chr3 GO:0002931 Not Cancer Driver No 26 0.1721854304635761 0 0 0.0 24
CIB1-201 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0002931 Not Cancer Driver No 16 0.0837696335078534 6 1 0.0052356020942408 0
CPEB4-201 CPEB4 Q17RY0 Cytoplasmic polyadenylation element-binding protein 4 chr5 GO:0002931 Not Cancer Driver No 65 0.0891632373113854 444 39 0.0534979423868312 0
CSF1-201 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0002931 Not Cancer Driver No 56 0.1010830324909747 342 38 0.0685920577617328 0
CSF1R-210 CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0002931 Census Yes 101 0.1039094650205761 124 12 0.0123456790123456 20
CX3CL1-201 CX3CL1 P78423 Fractalkine chr16 GO:0002931 Not Cancer Driver No 53 0.1335012594458438 259 36 0.0906801007556675 0
CX3CR1-202 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0002931 Not Cancer Driver No 60 0.1690140845070422 0 0 0.0 0
EEF2K-201 EEF2K O00418 Eukaryotic elongation factor 2 kinase chr16 GO:0002931 Not Cancer Driver No 80 0.1103448275862069 311 30 0.0413793103448275 0
EGR1-201 EGR1 P18146 Early growth response protein 1 chr5 GO:0002931 Not Cancer Driver No 63 0.1160220994475138 503 57 0.1049723756906077 0
FAIM2-201 FAIM2 Q9BWQ8 Protein lifeguard 2 chr12 GO:0002931 Not Cancer Driver No 29 0.0917721518987341 55 8 0.0253164556962025 0
GJB2-202 GJB2 P29033 Gap junction beta-2 protein chr13 GO:0002931 Not Cancer Driver No 25 0.1106194690265486 0 0 0.0 41
GPR151-201 GPR151 Q8TDV0 G-protein coupled receptor 151 chr5 GO:0002931 Not Cancer Driver No 44 0.1050119331742243 97 10 0.0238663484486873 0
GPR31-201 GPR31 O00270 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor chr6 GO:0002931 Not Cancer Driver No 45 0.1410658307210031 14 4 0.012539184952978 0
HK2-201 HK2 P52789 Hexokinase-2 chr2 GO:0002931 Not Cancer Driver No 108 0.1177753544165757 78 2 0.0021810250817884 0
HYOU1-218 HYOU1 Q9Y4L1 Hypoxia up-regulated protein 1 chr11 GO:0002931 Not Cancer Driver No 98 0.0980980980980981 373 36 0.036036036036036 0
ITGAM-201 ITGAM P11215 Integrin alpha-M chr16 GO:0002931 Not Cancer Driver No 142 0.1232638888888889 133 9 0.0078125 0
KCNJ11-201 KCNJ11 Q14654 ATP-sensitive inward rectifier potassium channel 11 chr11 GO:0002931 Not Cancer Driver No 34 0.0871794871794871 20 1 0.0025641025641025 37
KCNJ8-201 KCNJ8 Q15842 ATP-sensitive inward rectifier potassium channel 8 chr12 GO:0002931 Not Cancer Driver No 78 0.1839622641509433 69 17 0.0400943396226415 1
MAP2K3-202 MAP2K3 P46734 Dual specificity mitogen-activated protein kinase kinase 3 chr17 GO:0002931 Not Cancer Driver No 74 0.2132564841498559 76 19 0.0547550432276657 0
MAP2K6-206 MAP2K6 P52564 Dual specificity mitogen-activated protein kinase kinase 6 chr17 GO:0002931 Not Cancer Driver No 28 0.0838323353293413 55 6 0.0179640718562874 0
MAP3K5-201 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0002931 Not Cancer Driver No 146 0.106259097525473 244 23 0.0167394468704512 0
MEF2C-209 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0002931 Not Cancer Driver No 54 0.1141649048625792 408 51 0.1078224101479915 2
MLYCD-201 MLYCD O95822 Malonyl-CoA decarboxylase, mitochondrial chr16 GO:0002931 Not Cancer Driver No 26 0.0527383367139959 84 0 0.0 0
MYB-205 MYB P10242 Transcriptional activator Myb chr6 GO:0002931 Census Yes 69 0.1078125 528 57 0.0890625 0
NDNF-201 NDNF Q8TB73 Protein NDNF chr4 GO:0002931 Not Cancer Driver No 90 0.1584507042253521 130 22 0.0387323943661971 1
NFE2L2-201 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0002931 Census, Compendium Yes 235 0.3884297520661157 402 59 0.0975206611570247 4
NPPC-202 NPPC P23582 C-type natriuretic peptide chr2 GO:0002931 Not Cancer Driver No 8 0.0634920634920634 82 5 0.0396825396825396 0
NPR3-201 NPR3 P17342 Atrial natriuretic peptide receptor 3 chr5 GO:0002931 Not Cancer Driver No 79 0.1460258780036968 58 7 0.0129390018484288 2
NQO1-201 NQO1 P15559 NAD(P)H dehydrogenase [quinone] 1 chr16 GO:0002931 Not Cancer Driver No 11 0.0401459854014598 10 0 0.0 0
P2RX2-208 P2RX2 Q9UBL9 P2X purinoceptor 2 chr12 GO:0002931 Not Cancer Driver No 53 0.1125265392781316 105 10 0.0212314225053078 2
P2RX4-202 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0002931 Not Cancer Driver No 20 0.0515463917525773 0 0 0.0 0
P2RX7-202 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0002931 Not Cancer Driver No 37 0.0621848739495798 16 1 0.0016806722689075 0
PANX1-201 PANX1 Q96RD7 Pannexin-1 chr11 GO:0002931 Not Cancer Driver No 40 0.0938967136150234 45 5 0.0117370892018779 2
PANX2-202 PANX2 Q96RD6 Pannexin-2 chr22 GO:0002931 Not Cancer Driver No 51 0.0753323485967503 293 9 0.0132939438700147 0
PER2-201 PER2 O15055 Period circadian protein homolog 2 chr2 GO:0002931 Not Cancer Driver No 118 0.0940239043824701 783 72 0.0573705179282868 1
PIK3CB-214 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:0002931 Census, Compendium Yes 112 0.1046728971962616 42 3 0.002803738317757 0
PINK1-201 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0002931 Not Cancer Driver No 46 0.0791738382099827 99 8 0.0137693631669535 24
PPIF-201 PPIF P30405 Peptidyl-prolyl cis-trans isomerase F, mitochondrial chr10 GO:0002931 Not Cancer Driver No 13 0.0628019323671497 44 2 0.0096618357487922 0
PTK2B-201 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0002931 Not Cancer Driver No 117 0.1159563924677899 263 23 0.0227948463825569 0
RCAN1-201 RCAN1 P53805 Calcipressin-1 chr21 GO:0002931 Not Cancer Driver No 20 0.0793650793650793 103 6 0.0238095238095238 0
RELA-202 RELA Q04206 Transcription factor p65 chr11 GO:0002931 Compendium Yes 53 0.0961887477313974 401 32 0.058076225045372 0
REST-201 REST Q13127 RE1-silencing transcription factor chr4 GO:0002931 Not Cancer Driver No 86 0.0783956244302643 872 68 0.0619872379216043 4
RNLS-201 RNLS Q5VYX0 Renalase chr10 GO:0002931 Not Cancer Driver No 33 0.0964912280701754 15 1 0.0029239766081871 0
ROCK2-202 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0002931 Not Cancer Driver No 110 0.0792507204610951 734 61 0.0439481268011527 0
SLC26A5-201 SLC26A5 P58743 Prestin chr7 GO:0002931 Not Cancer Driver No 94 0.1263440860215053 59 8 0.010752688172043 0
SLC8A2-201 SLC8A2 Q9UPR5 Sodium/calcium exchanger 2 chr19 GO:0002931 Not Cancer Driver No 104 0.1129207383279044 143 19 0.020629750271444 0
SOS1-202 SOS1 Q07889 Son of sevenless homolog 1 chr2 GO:0002931 Compendium Yes 155 0.1162790697674418 459 47 0.0352588147036759 32
SQSTM1-202 SQSTM1 Q13501 Sequestosome-1 chr5 GO:0002931 Not Cancer Driver No 41 0.0931818181818181 271 24 0.0545454545454545 30
STUB1-201 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:0002931 Not Cancer Driver No 29 0.0957095709570957 113 11 0.0363036303630363 11
TIGAR-201 TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:0002931 Not Cancer Driver No 33 0.1222222222222222 39 8 0.0296296296296296 0
TP53-201 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0002931 Census, Compendium Yes 2742 6.977099236641221 282 1364 3.470737913486005 60
TREM2-202 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0002931 Not Cancer Driver No 31 0.1347826086956521 27 2 0.008695652173913 1
UCHL1-201 UCHL1 P09936 Ubiquitin carboxyl-terminal hydrolase isozyme L1 chr4 GO:0002931 Not Cancer Driver No 23 0.1031390134529148 34 5 0.0224215246636771 4