Total number of protein in "GO:0003684" GO term: 64
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| APEX1-201 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | GO:0003684 | Not Cancer Driver | No | 23 | 0.0723270440251572 | 104 | 9 | 0.0283018867924528 | 0 |
| APTX-203 | APTX | Q7Z2E3 | Aprataxin | chr9 | GO:0003684 | Not Cancer Driver | No | 19 | 0.0555555555555555 | 113 | 6 | 0.0175438596491228 | 9 |
| AUNIP-201 | AUNIP | Q9H7T9 | Aurora kinase A and ninein-interacting protein | chr1 | GO:0003684 | Not Cancer Driver | No | 14 | 0.0392156862745098 | 341 | 13 | 0.0364145658263305 | 0 |
| BRCA1-203 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | GO:0003684 | Census, Compendium | Yes | 167 | 0.0896403650026838 | 1466 | 127 | 0.0681696188942565 | 34 |
| CREBBP-201 | CREBBP | Q92793 | CREB-binding protein | chr16 | GO:0003684 | Census, Compendium | Yes | 217 | 0.0888615888615888 | 1801 | 91 | 0.0372645372645372 | 30 |
| CRY2-211 | CRY2 | Q49AN0 | Cryptochrome-2 | chr11 | GO:0003684 | Not Cancer Driver | No | 54 | 0.0910623946037099 | 100 | 8 | 0.0134907251264755 | 0 |
| CUL4B-231 | CUL4B | Q13620 | Cullin-4B | chrX | GO:0003684 | Not Cancer Driver | No | 83 | 0.0909090909090909 | 207 | 23 | 0.0251916757940854 | 2 |
| DCLRE1A-201 | DCLRE1A | Q6PJP8 | DNA cross-link repair 1A protein | chr10 | GO:0003684 | Not Cancer Driver | No | 77 | 0.0740384615384615 | 515 | 42 | 0.0403846153846153 | 0 |
| DCLRE1B-203 | DCLRE1B | Q9H816 | 5' exonuclease Apollo | chr1 | GO:0003684 | Not Cancer Driver | No | 44 | 0.0827067669172932 | 127 | 12 | 0.0225563909774436 | 1 |
| DCLRE1C-209 | DCLRE1C | Q96SD1 | Protein artemis | chr10 | GO:0003684 | Not Cancer Driver | No | 56 | 0.0809248554913294 | 277 | 21 | 0.0303468208092485 | 3 |
| DDB1-201 | DDB1 | Q16531 | DNA damage-binding protein 1 | chr11 | GO:0003684 | Not Cancer Driver | No | 98 | 0.0859649122807017 | 50 | 8 | 0.0070175438596491 | 3 |
| DDB2-201 | DDB2 | Q92466 | DNA damage-binding protein 2 | chr11 | GO:0003684 | Census, Compendium | Yes | 35 | 0.081967213114754 | 71 | 5 | 0.0117096018735363 | 2 |
| EP300-201 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | GO:0003684 | Census, Compendium | Yes | 203 | 0.084092792046396 | 1792 | 84 | 0.0347970173985087 | 1 |
| ERCC1-202 | ERCC1 | P07992 | DNA excision repair protein ERCC-1 | chr19 | GO:0003684 | Not Cancer Driver | No | 36 | 0.1212121212121212 | 107 | 14 | 0.0471380471380471 | 1 |
| ERCC2-204 | ERCC2 | P18074 | General transcription and DNA repair factor IIH helicase subunit XPD | chr19 | GO:0003684 | Census, Compendium | Yes | 103 | 0.1355263157894737 | 5 | 0 | 0.0 | 30 |
| ERCC3-201 | ERCC3 | P19447 | General transcription and DNA repair factor IIH helicase subunit XPB | chr2 | GO:0003684 | Census, Compendium | Yes | 67 | 0.0856777493606138 | 208 | 14 | 0.0179028132992327 | 2 |
| ERCC4-201 | ERCC4 | Q92889 | DNA repair endonuclease XPF | chr16 | GO:0003684 | Census | Yes | 81 | 0.0884279475982532 | 226 | 19 | 0.0207423580786026 | 15 |
| ERCC5-212 | ERCC5 | P28715 | DNA excision repair protein ERCC-5 | chr13 | GO:0003684 | Census | Yes | 115 | 0.096964586846543 | 819 | 78 | 0.0657672849915683 | 6 |
| FANCG-201 | FANCG | O15287 | Fanconi anemia group G protein | chr9 | GO:0003684 | Census | Yes | 43 | 0.0691318327974276 | 48 | 1 | 0.0016077170418006 | 1 |
| FEN1-201 | FEN1 | P39748 | Flap endonuclease 1 | chr11 | GO:0003684 | Census | Yes | 29 | 0.0763157894736842 | 111 | 13 | 0.0342105263157894 | 0 |
| H2AX-202 | H2AX | P16104 | Histone H2AX | chr11 | GO:0003684 | Not Cancer Driver | No | 19 | 0.1328671328671328 | 68 | 8 | 0.0559440559440559 | 0 |
| HMGB1-203 | HMGB1 | P09429 | High mobility group protein B1 | chr13 | GO:0003684 | Not Cancer Driver | No | 10 | 0.0465116279069767 | 202 | 7 | 0.0325581395348837 | 0 |
| HMGB2-201 | HMGB2 | P26583 | High mobility group protein B2 | chr4 | GO:0003684 | Not Cancer Driver | No | 26 | 0.124401913875598 | 207 | 26 | 0.124401913875598 | 0 |
| KDM4D-201 | KDM4D | Q6B0I6 | Lysine-specific demethylase 4D | chr11 | GO:0003684 | Not Cancer Driver | No | 66 | 0.1261950286806883 | 215 | 24 | 0.0458891013384321 | 0 |
| MPG-201 | MPG | P29372 | DNA-3-methyladenine glycosylase | chr16 | GO:0003684 | Not Cancer Driver | No | 31 | 0.1040268456375839 | 143 | 18 | 0.0604026845637583 | 0 |
| NBN-201 | NBN | O60934 | Nibrin | chr8 | GO:0003684 | Census | Yes | 63 | 0.0835543766578249 | 420 | 45 | 0.059681697612732 | 1 |
| NEIL1-201 | NEIL1 | Q96FI4 | Endonuclease 8-like 1 | chr15 | GO:0003684 | Not Cancer Driver | No | 32 | 0.082051282051282 | 166 | 10 | 0.0256410256410256 | 0 |
| NEIL2-201 | NEIL2 | Q969S2 | Endonuclease 8-like 2 | chr8 | GO:0003684 | Not Cancer Driver | No | 26 | 0.0783132530120482 | 145 | 13 | 0.0391566265060241 | 0 |
| NEIL3-201 | NEIL3 | Q8TAT5 | Endonuclease 8-like 3 | chr4 | GO:0003684 | Not Cancer Driver | No | 53 | 0.0876033057851239 | 136 | 9 | 0.0148760330578512 | 0 |
| NTHL1-201 | NTHL1 | P78549 | Endonuclease III-like protein 1 | chr16 | GO:0003684 | Census | Yes | 34 | 0.1089743589743589 | 147 | 15 | 0.048076923076923 | 0 |
| OGG1-205 | OGG1 | O15527 | N-glycosylase/DNA lyase | chr3 | GO:0003684 | Not Cancer Driver | No | 26 | 0.0753623188405797 | 72 | 4 | 0.0115942028985507 | 0 |
| PARP1-203 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | GO:0003684 | Not Cancer Driver | No | 88 | 0.0867850098619329 | 322 | 28 | 0.0276134122287968 | 0 |
| PARP2-201 | PARP2 | Q9UGN5 | Poly [ADP-ribose] polymerase 2 | chr14 | GO:0003684 | Not Cancer Driver | No | 44 | 0.0754716981132075 | 172 | 16 | 0.0274442538593482 | 0 |
| PCNA-201 | PCNA | P12004 | Proliferating cell nuclear antigen | chr20 | GO:0003684 | Not Cancer Driver | No | 19 | 0.0727969348659003 | 22 | 2 | 0.0076628352490421 | 1 |
| PNKP-201 | PNKP | Q96T60 | Bifunctional polynucleotide phosphatase/kinase | chr19 | GO:0003684 | Not Cancer Driver | No | 46 | 0.0882917466410748 | 177 | 21 | 0.0403071017274472 | 4 |
| POLB-201 | POLB | P06746 | DNA polymerase beta | chr8 | GO:0003684 | Not Cancer Driver | No | 32 | 0.0955223880597015 | 87 | 8 | 0.0238805970149253 | 0 |
| POLD1-201 | POLD1 | P28340 | DNA polymerase delta catalytic subunit | chr19 | GO:0003684 | Census, Compendium | Yes | 118 | 0.1065943992773261 | 210 | 17 | 0.015356820234869 | 2 |
| POLH-202 | POLH | Q9Y253 | DNA polymerase eta | chr6 | GO:0003684 | Not Cancer Driver | No | 49 | 0.0687237026647966 | 291 | 15 | 0.0210378681626928 | 10 |
| POLI-208 | POLI | Q9UNA4 | DNA polymerase iota | chr18 | GO:0003684 | Not Cancer Driver | No | 50 | 0.0675675675675675 | 302 | 20 | 0.027027027027027 | 0 |
| POLK-201 | POLK | Q9UBT6 | DNA polymerase kappa | chr5 | GO:0003684 | Not Cancer Driver | No | 66 | 0.0758620689655172 | 294 | 25 | 0.028735632183908 | 0 |
| POLQ-201 | POLQ | O75417 | DNA polymerase theta | chr3 | GO:0003684 | Census, Compendium | Yes | 274 | 0.1057915057915057 | 956 | 94 | 0.0362934362934362 | 0 |
| RAD1-203 | RAD1 | O60671 | Cell cycle checkpoint protein RAD1 | chr5 | GO:0003684 | Not Cancer Driver | No | 19 | 0.0673758865248227 | 4 | 0 | 0.0 | 0 |
| RAD18-201 | RAD18 | Q9NS91 | E3 ubiquitin-protein ligase RAD18 | chr3 | GO:0003684 | Not Cancer Driver | No | 42 | 0.0848484848484848 | 330 | 31 | 0.0626262626262626 | 0 |
| RAD23A-203 | RAD23A | P54725 | UV excision repair protein RAD23 homolog A | chr19 | GO:0003684 | Not Cancer Driver | No | 41 | 0.1129476584022038 | 284 | 34 | 0.09366391184573 | 0 |
| RAD23B-201 | RAD23B | P54727 | UV excision repair protein RAD23 homolog B | chr9 | GO:0003684 | Not Cancer Driver | No | 29 | 0.0709046454767726 | 326 | 24 | 0.0586797066014669 | 0 |
| RBBP8-201 | RBBP8 | Q99708 | DNA endonuclease RBBP8 | chr18 | GO:0003684 | Not Cancer Driver | No | 72 | 0.0802675585284281 | 751 | 54 | 0.060200668896321 | 1 |
| REV1-201 | REV1 | Q9UBZ9 | DNA repair protein REV1 | chr2 | GO:0003684 | Not Cancer Driver | No | 91 | 0.0727418065547561 | 663 | 51 | 0.0407673860911271 | 0 |
| RPA1-201 | RPA1 | P27694 | Replication protein A 70 kDa DNA-binding subunit | chr17 | GO:0003684 | Not Cancer Driver | No | 45 | 0.073051948051948 | 98 | 7 | 0.0113636363636363 | 1 |
| RPA2-203 | RPA2 | P15927 | Replication protein A 32 kDa subunit | chr1 | GO:0003684 | Not Cancer Driver | No | 20 | 0.074074074074074 | 117 | 12 | 0.0444444444444444 | 0 |
| RPA3-201 | RPA3 | P35244 | Replication protein A 14 kDa subunit | chr7 | GO:0003684 | Not Cancer Driver | No | 10 | 0.0826446280991735 | 4 | 1 | 0.0082644628099173 | 0 |
| RPS3-217 | RPS3 | P23396 | Small ribosomal subunit protein uS3 | chr11 | GO:0003684 | Not Cancer Driver | No | 22 | 0.0905349794238683 | 48 | 4 | 0.0164609053497942 | 0 |
| SDE2-201 | SDE2 | Q6IQ49 | Splicing regulator SDE2 | chr1 | GO:0003684 | Not Cancer Driver | No | 40 | 0.0886917960088691 | 290 | 23 | 0.0509977827050997 | 0 |
| SIRT6-202 | SIRT6 | Q8N6T7 | NAD-dependent protein deacylase sirtuin-6 | chr19 | GO:0003684 | Not Cancer Driver | No | 24 | 0.0676056338028169 | 165 | 6 | 0.0169014084507042 | 0 |
| SMC6-207 | SMC6 | Q96SB8 | Structural maintenance of chromosomes protein 6 | chr2 | GO:0003684 | Not Cancer Driver | No | 95 | 0.0870760769935838 | 459 | 43 | 0.0394133822181484 | 0 |
| TDG-202 | TDG | Q13569 | G/T mismatch-specific thymine DNA glycosylase | chr12 | GO:0003684 | Not Cancer Driver | No | 45 | 0.1097560975609756 | 186 | 21 | 0.0512195121951219 | 0 |
| TP53BP1-201 | TP53BP1 | Q12888 | TP53-binding protein 1 | chr15 | GO:0003684 | Not Cancer Driver | No | 159 | 0.0806288032454361 | 1638 | 131 | 0.0664300202839756 | 0 |
| TP63-201 | TP63 | Q9H3D4 | Tumor protein 63 | chr3 | GO:0003684 | Census, Compendium | Yes | 198 | 0.2911764705882353 | 398 | 120 | 0.1764705882352941 | 21 |
| UNG-201 | UNG | P13051 | Uracil-DNA glycosylase | chr12 | GO:0003684 | Not Cancer Driver | No | 28 | 0.0894568690095846 | 96 | 12 | 0.0383386581469648 | 1 |
| XNDC1N-210 | XNDC1N | Q6ZNB5 | Protein XNDC1N | chr11 | GO:0003684 | Not Cancer Driver | No | 1 | 0.0042735042735042 | 28 | 0 | 0.0 | 0 |
| XPA-201 | XPA | P23025 | DNA repair protein complementing XP-A cells | chr9 | GO:0003684 | Census | Yes | 12 | 0.0439560439560439 | 121 | 6 | 0.0219780219780219 | 5 |
| XPC-201 | XPC | Q01831 | DNA repair protein complementing XP-C cells | chr3 | GO:0003684 | Census, Compendium | Yes | 64 | 0.0680851063829787 | 484 | 34 | 0.0361702127659574 | 2 |
| XRCC5-201 | XRCC5 | P13010 | X-ray repair cross-complementing protein 5 | chr2 | GO:0003684 | Not Cancer Driver | No | 53 | 0.0724043715846994 | 119 | 6 | 0.0081967213114754 | 0 |
| XRCC6-202 | XRCC6 | P12956 | X-ray repair cross-complementing protein 6 | chr22 | GO:0003684 | Not Cancer Driver | No | 49 | 0.0804597701149425 | 140 | 8 | 0.0131362889983579 | 0 |
| ZNF432-201 | ZNF432 | O94892 | Zinc finger protein 432 | chr19 | GO:0003684 | Not Cancer Driver | No | 51 | 0.0782208588957055 | 157 | 10 | 0.0153374233128834 | 0 |