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Total number of protein in "GO:0003690" GO term:  103

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AFF3-221 AFF3 P51826 AF4/FMR2 family member 3 chr2 GO:0003690 Census, Compendium Yes 197 0.1606851549755301 1025 169 0.1378466557911908 3
AIM2-202 AIM2 O14862 Interferon-inducible protein AIM2 chr1 GO:0003690 Not Cancer Driver No 54 0.1574344023323615 79 17 0.0495626822157434 0
AKAP8-201 AKAP8 O43823 A-kinase anchor protein 8 chr19 GO:0003690 Not Cancer Driver No 66 0.0953757225433526 566 57 0.0823699421965317 0
APTX-203 APTX Q7Z2E3 Aprataxin chr9 GO:0003690 Not Cancer Driver No 19 0.0555555555555555 113 6 0.0175438596491228 9
BANF1-201 BANF1 O75531 Barrier-to-autointegration factor chr11 GO:0003690 Not Cancer Driver No 5 0.0561797752808988 11 2 0.0224719101123595 1
CAMTA1-201 CAMTA1 Q9Y6Y1 Calmodulin-binding transcription activator 1 chr1 GO:0003690 Census, Compendium Yes 233 0.1392707710699342 886 123 0.0735206216377764 0
CAMTA2-201 CAMTA2 O94983 Calmodulin-binding transcription activator 2 chr17 GO:0003690 Not Cancer Driver No 104 0.086522462562396 615 62 0.0515806988352745 0
CENPS-201 CENPS Q8N2Z9 Centromere protein S chr1 GO:0003690 Not Cancer Driver No 6 0.0434782608695652 66 2 0.0144927536231884 0
CENPS-CORT-205 CENPS Q8N2Z9 Centromere protein S chr1 GO:0003690 Not Cancer Driver No 6 0.0434782608695652 66 2 0.0144927536231884 0
CENPX-202 CENPX A8MT69 Centromere protein X chr17 GO:0003690 Not Cancer Driver No 3 0.037037037037037 0 0 0.0 0
CGAS-201 CGAS Q8N884 Cyclic GMP-AMP synthase chr6 GO:0003690 Not Cancer Driver No 33 0.0632183908045977 175 6 0.0114942528735632 0
CGGBP1-206 CGGBP1 Q9UFW8 CGG triplet repeat-binding protein 1 chr3 GO:0003690 Not Cancer Driver No 13 0.0778443113772455 106 9 0.0538922155688622 0
CRY1-201 CRY1 Q16526 Cryptochrome-1 chr12 GO:0003690 Not Cancer Driver No 53 0.0904436860068259 91 3 0.0051194539249146 0
DDX11-229 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:0003690 Not Cancer Driver No 95 0.0979381443298969 282 32 0.0329896907216494 1
DDX60-201 DDX60 Q8IY21 Probable ATP-dependent RNA helicase DDX60 chr4 GO:0003690 Not Cancer Driver No 162 0.094626168224299 132 6 0.0035046728971962 0
DHX9-201 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0003690 Compendium Yes 125 0.0984251968503937 332 30 0.0236220472440944 0
DMC1-201 DMC1 Q14565 Meiotic recombination protein DMC1/LIM15 homolog chr22 GO:0003690 Not Cancer Driver No 28 0.0823529411764705 49 5 0.0147058823529411 0
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 GO:0003690 Census, Compendium Yes 346 0.2859504132231405 223 30 0.024793388429752 1
ENST00000681750 RIGI O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0003690 Not Cancer Driver No 68 0.0777142857142857 58 5 0.0057142857142857 2
ERCC5-212 ERCC5 P28715 DNA excision repair protein ERCC-5 chr13 GO:0003690 Census Yes 115 0.096964586846543 819 78 0.0657672849915683 6
FBH1-201 FBH1 Q8NFZ0 F-box DNA helicase 1 chr10 GO:0003690 Not Cancer Driver No 102 0.0977948226270374 192 28 0.0268456375838926 0
FEN1-201 FEN1 P39748 Flap endonuclease 1 chr11 GO:0003690 Census Yes 29 0.0763157894736842 111 13 0.0342105263157894 0
GTF2H4-201 GTF2H4 Q92759 General transcription factor IIH subunit 4 chr6 GO:0003690 Not Cancer Driver No 33 0.0714285714285714 30 4 0.0086580086580086 0
H1-0-201 H1-0 P07305 Histone H1.0 chr22 GO:0003690 Not Cancer Driver No 6 0.0309278350515463 194 6 0.0309278350515463 0
H1-1-201 H1-1 Q02539 Histone H1.1 chr6 GO:0003690 Not Cancer Driver No 13 0.0604651162790697 212 12 0.055813953488372 0
H1-10-201 H1-10 Q92522 Histone H1.10 chr3 GO:0003690 Not Cancer Driver No 11 0.0516431924882629 200 12 0.056338028169014 0
H1-2-201 H1-2 P16403 Histone H1.2 chr6 GO:0003690 Not Cancer Driver No 28 0.1314553990610328 214 28 0.1314553990610328 0
H1-3-201 H1-3 P16402 Histone H1.3 chr6 GO:0003690 Not Cancer Driver No 14 0.0633484162895927 216 12 0.0542986425339366 0
H1-4-201 H1-4 P10412 Histone H1.4 chr6 GO:0003690 Not Cancer Driver No 33 0.1506849315068493 213 32 0.1461187214611872 0
H1-5-201 H1-5 P16401 Histone H1.5 chr6 GO:0003690 Not Cancer Driver No 13 0.0575221238938053 226 13 0.0575221238938053 0
H1-6-201 H1-6 P22492 Histone H1t chr6 GO:0003690 Not Cancer Driver No 38 0.1835748792270531 160 30 0.144927536231884 0
H1-7-201 H1-7 Q75WM6 Testis-specific H1 histone chr12 GO:0003690 Not Cancer Driver No 43 0.1686274509803921 253 43 0.1686274509803921 0
H1-8-201 H1-8 Q8IZA3 Histone H1.8 chr3 GO:0003690 Not Cancer Driver No 25 0.0722543352601156 326 26 0.0751445086705202 0
HLF-201 HLF Q16534 Hepatic leukemia factor chr17 GO:0003690 Census Yes 46 0.1559322033898305 264 42 0.1423728813559322 0
HMGB1-203 HMGB1 P09429 High mobility group protein B1 chr13 GO:0003690 Not Cancer Driver No 10 0.0465116279069767 202 7 0.0325581395348837 0
HMGB2-201 HMGB2 P26583 High mobility group protein B2 chr4 GO:0003690 Not Cancer Driver No 26 0.124401913875598 207 26 0.124401913875598 0
HMGB3-201 HMGB3 O15347 High mobility group protein B3 chrX GO:0003690 Not Cancer Driver No 20 0.1 182 17 0.085 0
HNRNPU-226 HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0003690 Not Cancer Driver No 57 0.069090909090909 505 36 0.0436363636363636 0
IFI16-201 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0003690 Not Cancer Driver No 102 0.129936305732484 422 61 0.0777070063694267 0
IFIT5-201 IFIT5 Q13325 Interferon-induced protein with tetratricopeptide repeats 5 chr10 GO:0003690 Not Cancer Driver No 31 0.0643153526970954 19 0 0.0 0
KIN-201 KIN O60870 DNA/RNA-binding protein KIN17 chr10 GO:0003690 Not Cancer Driver No 36 0.0916030534351145 137 10 0.0254452926208651 0
LSM14A-201 LSM14A Q8ND56 Protein LSM14 homolog A chr19 GO:0003690 Census Yes 51 0.1101511879049676 408 47 0.101511879049676 0
MAPT-212 MAPT P10636 Microtubule-associated protein tau chr17 GO:0003690 Not Cancer Driver No 100 0.1319261213720316 750 99 0.1306068601583113 17
MAU2-201 MAU2 Q9Y6X3 MAU2 chromatid cohesion factor homolog chr19 GO:0003690 Not Cancer Driver No 54 0.0880913539967373 36 1 0.0016313213703099 0
MEN1-203 MEN1 O00255 Menin chr11 GO:0003690 Census, Compendium Yes 50 0.08130081300813 230 9 0.0146341463414634 80
MND1-201 MND1 Q9BWT6 Meiotic nuclear division protein 1 homolog chr4 GO:0003690 Not Cancer Driver No 19 0.0926829268292682 85 6 0.0292682926829268 0
MNDA-201 MNDA P41218 Myeloid cell nuclear differentiation antigen chr1 GO:0003690 Not Cancer Driver No 142 0.3488943488943489 173 63 0.1547911547911548 0
MRE11-201 MRE11 P49959 Double-strand break repair protein MRE11 chr11 GO:0003690 Not Cancer Driver No 61 0.0861581920903954 292 28 0.03954802259887 1
MSH2-201 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0003690 Census Yes 55 0.0588865096359743 37 1 0.0010706638115631 63
MSH3-201 MSH3 P20585 DNA mismatch repair protein Msh3 chr5 GO:0003690 Not Cancer Driver No 65 0.0571679859278803 218 11 0.0096745822339489 0
MSH4-201 MSH4 O15457 MutS protein homolog 4 chr1 GO:0003690 Not Cancer Driver No 122 0.1303418803418803 198 32 0.0341880341880341 3
MSH5-203 MSH5 O43196 MutS protein homolog 5 chr6 GO:0003690 Not Cancer Driver No 67 0.0803357314148681 86 6 0.0071942446043165 1
MSH5-SAPCD1-207 MSH5 O43196 MutS protein homolog 5 chr6 GO:0003690 Not Cancer Driver No 67 0.0787309048178613 92 6 0.0070505287896592 1
MSH6-201 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 GO:0003690 Census Yes 92 0.0676470588235294 389 26 0.0191176470588235 6
MTERF1-201 MTERF1 Q99551 Transcription termination factor 1, mitochondrial chr7 GO:0003690 Not Cancer Driver No 24 0.0601503759398496 0 0 0.0 0
MTERF2-201 MTERF2 Q49AM1 Transcription termination factor 2, mitochondrial chr12 GO:0003690 Not Cancer Driver No 32 0.0831168831168831 0 0 0.0 0
MTERF4-202 MTERF4 Q7Z6M4 Transcription termination factor 4, mitochondrial chr2 GO:0003690 Not Cancer Driver No 30 0.0787401574803149 100 5 0.0131233595800524 0
NEIL3-201 NEIL3 Q8TAT5 Endonuclease 8-like 3 chr4 GO:0003690 Not Cancer Driver No 53 0.0876033057851239 136 9 0.0148760330578512 0
NKX2-8-201 NKX2-8 O15522 Homeobox protein Nkx-2.8 chr14 GO:0003690 Not Cancer Driver No 13 0.0543933054393305 163 13 0.0543933054393305 0
NLRP1-208 NLRP1 Q9C000 NACHT, LRR and PYD domains-containing protein 1 chr17 GO:0003690 Not Cancer Driver No 169 0.1147318397827562 341 45 0.0305498981670061 6
NTHL1-201 NTHL1 P78549 Endonuclease III-like protein 1 chr16 GO:0003690 Census Yes 34 0.1089743589743589 147 15 0.048076923076923 0
NUCKS1-201 NUCKS1 Q9H1E3 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 chr1 GO:0003690 Not Cancer Driver No 25 0.102880658436214 243 25 0.102880658436214 0
PARK7-201 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0003690 Not Cancer Driver No 8 0.0423280423280423 30 0 0.0 6
PCID2-202 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 GO:0003690 Not Cancer Driver No 34 0.0852130325814536 13 2 0.0050125313283208 0
PNKP-201 PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 GO:0003690 Not Cancer Driver No 46 0.0882917466410748 177 21 0.0403071017274472 4
POLG2-201 POLG2 Q9UHN1 DNA polymerase subunit gamma-2, mitochondrial chr17 GO:0003690 Not Cancer Driver No 47 0.0969072164948453 46 3 0.0061855670103092 3
POLR3F-201 POLR3F Q9H1D9 DNA-directed RNA polymerase III subunit RPC6 chr20 GO:0003690 Not Cancer Driver No 12 0.0379746835443038 56 3 0.0094936708860759 0
PPARG-201 PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0003690 Census Yes 60 0.1188118811881188 44 3 0.0059405940594059 3
PQBP1-207 PQBP1 O60828 Polyglutamine-binding protein 1 chrX GO:0003690 Not Cancer Driver No 36 0.1358490566037735 233 31 0.1169811320754717 2
PRKDC-201 PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0003690 Not Cancer Driver No 385 0.0932655038759689 421 43 0.0104166666666666 2
PSMC3IP-202 PSMC3IP Q9P2W1 Homologous-pairing protein 2 homolog chr17 GO:0003690 Not Cancer Driver No 20 0.0921658986175115 73 6 0.0276497695852534 0
PYHIN1-203 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 GO:0003690 Not Cancer Driver No 139 0.282520325203252 293 81 0.1646341463414634 0
RAD51-201 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 GO:0003690 Not Cancer Driver No 27 0.079646017699115 48 3 0.0088495575221238 3
RAD51AP1-201 RAD51AP1 Q96B01 RAD51-associated protein 1 chr12 GO:0003690 Not Cancer Driver No 37 0.1051136363636363 337 35 0.0994318181818181 0
RAD51B-209 RAD51B O15315 DNA repair protein RAD51 homolog 2 chr14 GO:0003690 Census Yes 32 0.0833333333333333 12 0 0.0 0
RBMS1-201 RBMS1 P29558 RNA-binding motif, single-stranded-interacting protein 1 chr2 GO:0003690 Not Cancer Driver No 38 0.0935960591133004 244 27 0.0665024630541872 0
REXO4-202 REXO4 Q9GZR2 RNA exonuclease 4 chr9 GO:0003690 Not Cancer Driver No 24 0.0568720379146919 298 17 0.0402843601895734 0
RFC1-202 RFC1 P35251 Replication factor C subunit 1 chr4 GO:0003690 Not Cancer Driver No 80 0.0696864111498257 676 42 0.0365853658536585 0
RIGI-202 RIGI O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0003690 Not Cancer Driver No 78 0.0843243243243243 61 6 0.0064864864864864 2
RXRA-202 RXRA P19793 Retinoic acid receptor RXR-alpha chr9 GO:0003690 Compendium Yes 70 0.1515151515151515 184 18 0.0389610389610389 0
SAFB-201 SAFB Q15424 Scaffold attachment factor B1 chr19 GO:0003690 Not Cancer Driver No 44 0.048087431693989 911 43 0.0469945355191256 0
SATB1-201 SATB1 Q01826 DNA-binding protein SATB1 chr3 GO:0003690 Compendium Yes 104 0.1363040629095675 487 63 0.0825688073394495 9
SETMAR-201 SETMAR Q53H47 Histone-lysine N-methyltransferase SETMAR chr3 GO:0003690 Not Cancer Driver No 44 0.0643274853801169 155 11 0.0160818713450292 0
SMAD2-201 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:0003690 Census, Compendium Yes 58 0.1241970021413276 137 11 0.0235546038543897 3
SMC3-201 SMC3 Q9UQE7 Structural maintenance of chromosomes protein 3 chr10 GO:0003690 Not Cancer Driver No 116 0.09531635168447 605 49 0.0402629416598192 0
SP1-201 SP1 P08047 Transcription factor Sp1 chr12 GO:0003690 Not Cancer Driver No 67 0.0853503184713375 601 53 0.0675159235668789 0
SPRTN-202 SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 GO:0003690 Not Cancer Driver No 53 0.1083844580777096 254 26 0.0531697341513292 1
STAT1-201 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0003690 Not Cancer Driver No 100 0.1333333333333333 144 16 0.0213333333333333 23
SYCP1-202 SYCP1 Q15431 Synaptonemal complex protein 1 chr1 GO:0003690 Not Cancer Driver No 147 0.1506147540983606 604 80 0.081967213114754 0
TARDBP-201 TARDBP Q13148 TAR DNA-binding protein 43 chr1 GO:0003690 Not Cancer Driver No 36 0.0869565217391304 202 12 0.0289855072463768 21
TDG-202 TDG Q13569 G/T mismatch-specific thymine DNA glycosylase chr12 GO:0003690 Not Cancer Driver No 45 0.1097560975609756 186 21 0.0512195121951219 0
TDP1-201 TDP1 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 chr14 GO:0003690 Not Cancer Driver No 64 0.1052631578947368 179 20 0.0328947368421052 1
TOP1-201 TOP1 P11387 DNA topoisomerase 1 chr20 GO:0003690 Census, Compendium Yes 50 0.065359477124183 391 19 0.0248366013071895 0
TREX1-205 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0003690 Not Cancer Driver No 24 0.0764331210191082 98 7 0.0222929936305732 17
TSTD1-204 TSTD1 Q8NFU3 Thiosulfate:glutathione sulfurtransferase chr1 GO:0003690 Not Cancer Driver No 3 0.0260869565217391 4 0 0.0 0
WDR48-201 WDR48 Q8TAF3 WD repeat-containing protein 48 chr3 GO:0003690 Not Cancer Driver No 48 0.0709010339734121 125 16 0.0236336779911373 0
XRCC5-201 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0003690 Not Cancer Driver No 53 0.0724043715846994 119 6 0.0081967213114754 0
XRCC6-202 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 GO:0003690 Not Cancer Driver No 49 0.0804597701149425 140 8 0.0131362889983579 0
YBX1-201 YBX1 P67809 Y-box-binding protein 1 chr1 GO:0003690 Not Cancer Driver No 31 0.095679012345679 312 31 0.095679012345679 0
ZCCHC3-201 ZCCHC3 Q9NUD5 Zinc finger CCHC domain-containing protein 3 chr20 GO:0003690 Not Cancer Driver No 23 0.0570719602977667 161 1 0.0024813895781637 0
ZMPSTE24-201 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0003690 Not Cancer Driver No 46 0.0968421052631579 23 0 0.0 3
ZMYND11-203 ZMYND11 Q15326 Zinc finger MYND domain-containing protein 11 chr10 GO:0003690 Not Cancer Driver No 49 0.0813953488372093 184 19 0.0315614617940199 0
ZNF638-201 ZNF638 Q14966 Zinc finger protein 638 chr2 GO:0003690 Not Cancer Driver No 173 0.0874620829120323 1674 153 0.0773508594539939 0