Total number of protein in "GO:0004175" GO term: 71
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACE-202 | ACE | P12821 | Angiotensin-converting enzyme | chr17 | GO:0004175 | Not Cancer Driver | No | 152 | 0.116385911179173 | 87 | 5 | 0.0038284839203675 | 0 |
| ACE2-201 | ACE2 | Q9BYF1 | Angiotensin-converting enzyme 2 | chrX | GO:0004175 | Not Cancer Driver | No | 67 | 0.0832298136645962 | 68 | 4 | 0.0049689440993788 | 0 |
| ADAM10-201 | ADAM10 | O14672 | Disintegrin and metalloproteinase domain-containing protein 10 | chr15 | GO:0004175 | Not Cancer Driver | No | 73 | 0.0975935828877005 | 156 | 18 | 0.0240641711229946 | 4 |
| ADAM17-201 | ADAM17 | P78536 | Disintegrin and metalloproteinase domain-containing protein 17 | chr2 | GO:0004175 | Not Cancer Driver | No | 63 | 0.0764563106796116 | 182 | 17 | 0.020631067961165 | 0 |
| ADAMTS15-201 | ADAMTS15 | Q8TE58 | A disintegrin and metalloproteinase with thrombospondin motifs 15 | chr11 | GO:0004175 | Not Cancer Driver | No | 100 | 0.1052631578947368 | 141 | 17 | 0.0178947368421052 | 0 |
| ADAMTS3-201 | ADAMTS3 | O15072 | A disintegrin and metalloproteinase with thrombospondin motifs 3 | chr4 | GO:0004175 | Not Cancer Driver | No | 184 | 0.1526970954356846 | 295 | 53 | 0.0439834024896265 | 3 |
| ADAMTS5-201 | ADAMTS5 | Q9UNA0 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | chr21 | GO:0004175 | Not Cancer Driver | No | 173 | 0.1860215053763441 | 148 | 23 | 0.0247311827956989 | 0 |
| ADGRG6-201 | ADGRG6 | Q86SQ4 | Adhesion G-protein coupled receptor G6 | chr6 | GO:0004175 | Not Cancer Driver | No | 89 | 0.0728910728910729 | 23 | 0 | 0.0 | 2 |
| ATG4B-205 | ATG4B | Q9Y4P1 | Cysteine protease ATG4B | chr2 | GO:0004175 | Not Cancer Driver | No | 24 | 0.0610687022900763 | 13 | 2 | 0.005089058524173 | 0 |
| BACE1-201 | BACE1 | P56817 | Beta-secretase 1 | chr11 | GO:0004175 | Not Cancer Driver | No | 34 | 0.0678642714570858 | 53 | 2 | 0.0039920159680638 | 0 |
| CAPN7-201 | CAPN7 | Q9Y6W3 | Calpain-7 | chr3 | GO:0004175 | Not Cancer Driver | No | 60 | 0.07380073800738 | 92 | 9 | 0.011070110701107 | 0 |
| CASP1-212 | CASP1 | P29466 | Caspase-1 | chr11 | GO:0004175 | Not Cancer Driver | No | 54 | 0.1336633663366336 | 88 | 12 | 0.0297029702970297 | 0 |
| CELA2A-201 | CELA2A | P08217 | Chymotrypsin-like elastase family member 2A | chr1 | GO:0004175 | Not Cancer Driver | No | 36 | 0.1338289962825278 | 4 | 4 | 0.0148698884758364 | 2 |
| CLPP-201 | CLPP | Q16740 | ATP-dependent Clp protease proteolytic subunit, mitochondrial | chr19 | GO:0004175 | Not Cancer Driver | No | 15 | 0.0541516245487364 | 83 | 7 | 0.0252707581227436 | 3 |
| CMA1-202 | CMA1 | P23946 | Chymase | chr14 | GO:0004175 | Not Cancer Driver | No | 39 | 0.1578947368421052 | 9 | 1 | 0.0040485829959514 | 0 |
| CORIN-201 | CORIN | Q9Y5Q5 | Atrial natriuretic peptide-converting enzyme | chr4 | GO:0004175 | Not Cancer Driver | No | 153 | 0.1468330134357005 | 60 | 11 | 0.010556621880998 | 2 |
| CPNE1-204 | CPNE1 | Q99829 | Copine-1 | chr20 | GO:0004175 | Not Cancer Driver | No | 59 | 0.1098696461824953 | 81 | 9 | 0.0167597765363128 | 0 |
| CPS1-201 | CPS1 | P31327 | Carbamoyl-phosphate synthase [ammonia], mitochondrial | chr2 | GO:0004175 | Not Cancer Driver | No | 300 | 0.2 | 73 | 18 | 0.012 | 123 |
| CTSH-201 | CTSH | P09668 | Pro-cathepsin H | chr15 | GO:0004175 | Not Cancer Driver | No | 35 | 0.1044776119402985 | 4 | 0 | 0.0 | 0 |
| ECE1-203 | ECE1 | P42892 | Endothelin-converting enzyme 1 | chr1 | GO:0004175 | Not Cancer Driver | No | 95 | 0.1233766233766233 | 99 | 21 | 0.0272727272727272 | 1 |
| ELANE-201 | ELANE | P08246 | Neutrophil elastase | chr19 | GO:0004175 | Not Cancer Driver | No | 31 | 0.1161048689138576 | 18 | 1 | 0.0037453183520599 | 65 |
| ERAP1-202 | ERAP1 | Q9NZ08 | Endoplasmic reticulum aminopeptidase 1 | chr5 | GO:0004175 | Not Cancer Driver | No | 57 | 0.0605738575982996 | 70 | 1 | 0.0010626992561105 | 0 |
| ERAP2-202 | ERAP2 | Q6P179 | Endoplasmic reticulum aminopeptidase 2 | chr5 | GO:0004175 | Not Cancer Driver | No | 73 | 0.0760416666666666 | 23 | 4 | 0.0041666666666666 | 0 |
| F9-201 | F9 | P00740 | Coagulation factor IX | chrX | GO:0004175 | Not Cancer Driver | No | 90 | 0.1952277657266811 | 40 | 14 | 0.0303687635574837 | 105 |
| FAP-201 | FAP | Q12884 | Prolyl endopeptidase FAP | chr2 | GO:0004175 | Not Cancer Driver | No | 127 | 0.1671052631578947 | 6 | 2 | 0.0026315789473684 | 0 |
| FURIN-201 | FURIN | P09958 | Furin | chr15 | GO:0004175 | Not Cancer Driver | No | 72 | 0.0906801007556675 | 283 | 30 | 0.0377833753148614 | 0 |
| HGF-201 | HGF | P14210 | Hepatocyte growth factor | chr7 | GO:0004175 | Compendium | Yes | 196 | 0.2692307692307692 | 43 | 16 | 0.0219780219780219 | 0 |
| HTRA3-201 | HTRA3 | P83110 | Serine protease HTRA3 | chr4 | GO:0004175 | Not Cancer Driver | No | 47 | 0.1037527593818984 | 57 | 4 | 0.0088300220750551 | 0 |
| HTRA4-201 | HTRA4 | P83105 | Serine protease HTRA4 | chr8 | GO:0004175 | Not Cancer Driver | No | 42 | 0.088235294117647 | 15 | 0 | 0.0 | 0 |
| IDE-201 | IDE | P14735 | Insulin-degrading enzyme | chr10 | GO:0004175 | Not Cancer Driver | No | 65 | 0.0637880274779195 | 96 | 6 | 0.0058881256133464 | 0 |
| IMMP2L-202 | IMMP2L | Q96T52 | Mitochondrial inner membrane protease subunit 2 | chr7 | GO:0004175 | Not Cancer Driver | No | 32 | 0.1828571428571428 | 29 | 6 | 0.0342857142857142 | 0 |
| JMJD7-201 | JMJD7 | P0C870 | Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 | chr15 | GO:0004175 | Not Cancer Driver | No | 25 | 0.0791139240506329 | 0 | 0 | 0.0 | 0 |
| KDM8-201 | KDM8 | Q8N371 | Bifunctional peptidase and arginyl-hydroxylase JMJD5 | chr16 | GO:0004175 | Not Cancer Driver | No | 32 | 0.0769230769230769 | 29 | 6 | 0.0144230769230769 | 0 |
| KLK3-201 | KLK3 | P07288 | Prostate-specific antigen | chr19 | GO:0004175 | Not Cancer Driver | No | 54 | 0.2068965517241379 | 6 | 0 | 0.0 | 0 |
| LPA-201 | LPA | P08519 | Apolipoprotein(a) | chr6 | GO:0004175 | Not Cancer Driver | No | 302 | 0.1480392156862745 | 891 | 119 | 0.0583333333333333 | 0 |
| MALT1-208 | MALT1 | Q9UDY8 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | chr18 | GO:0004175 | Census, Compendium | Yes | 55 | 0.0667475728155339 | 139 | 9 | 0.0109223300970873 | 1 |
| MME-201 | MME | P08473 | Neprilysin | chr3 | GO:0004175 | Not Cancer Driver | No | 156 | 0.208 | 40 | 17 | 0.0226666666666666 | 4 |
| MMEL1-201 | MMEL1 | Q495T6 | Membrane metallo-endopeptidase-like 1 | chr1 | GO:0004175 | Not Cancer Driver | No | 102 | 0.1309370988446726 | 46 | 5 | 0.0064184852374839 | 0 |
| MMP1-201 | MMP1 | P03956 | Interstitial collagenase | chr11 | GO:0004175 | Not Cancer Driver | No | 65 | 0.138592750533049 | 114 | 16 | 0.0341151385927505 | 0 |
| MMP12-201 | MMP12 | P39900 | Macrophage metalloelastase | chr11 | GO:0004175 | Not Cancer Driver | No | 0 | 0.0 | 29 | 0 | 0.0 | 0 |
| MMP13-201 | MMP13 | P45452 | Collagenase 3 | chr11 | GO:0004175 | Not Cancer Driver | No | 87 | 0.1847133757961783 | 59 | 12 | 0.0254777070063694 | 5 |
| MMP14-201 | MMP14 | P50281 | Matrix metalloproteinase-14 | chr14 | GO:0004175 | Not Cancer Driver | No | 50 | 0.0859106529209622 | 120 | 6 | 0.0103092783505154 | 1 |
| MMP2-201 | MMP2 | P08253 | 72 kDa type IV collagenase | chr16 | GO:0004175 | Not Cancer Driver | No | 101 | 0.153030303030303 | 29 | 5 | 0.0075757575757575 | 2 |
| MMP3-201 | MMP3 | P08254 | Stromelysin-1 | chr11 | GO:0004175 | Not Cancer Driver | No | 74 | 0.1551362683438155 | 66 | 13 | 0.0272536687631027 | 0 |
| MMP7-201 | MMP7 | P09237 | Matrilysin | chr11 | GO:0004175 | Not Cancer Driver | No | 27 | 0.1011235955056179 | 70 | 2 | 0.0074906367041198 | 0 |
| MMP8-201 | MMP8 | P22894 | Neutrophil collagenase | chr11 | GO:0004175 | Not Cancer Driver | No | 62 | 0.1327623126338329 | 117 | 16 | 0.0342612419700214 | 0 |
| MMP9-201 | MMP9 | P14780 | Matrix metalloproteinase-9 | chr20 | GO:0004175 | Not Cancer Driver | No | 106 | 0.1499292786421499 | 124 | 24 | 0.0339462517680339 | 0 |
| MST1-202 | MST1 | P26927 | Hepatocyte growth factor-like protein | chr3 | GO:0004175 | Not Cancer Driver | No | 57 | 0.0786206896551724 | 171 | 9 | 0.0124137931034482 | 0 |
| NAPSA-201 | NAPSA | O96009 | Napsin-A | chr19 | GO:0004175 | Not Cancer Driver | No | 39 | 0.0928571428571428 | 14 | 0 | 0.0 | 0 |
| PARL-202 | PARL | Q9H300 | Presenilin-associated rhomboid-like protein, mitochondrial | chr3 | GO:0004175 | Not Cancer Driver | No | 38 | 0.100263852242744 | 28 | 5 | 0.0131926121372031 | 0 |
| PCSK5-205 | PCSK5 | Q92824 | Proprotein convertase subtilisin/kexin type 5 | chr9 | GO:0004175 | Not Cancer Driver | No | 259 | 0.139247311827957 | 170 | 20 | 0.010752688172043 | 0 |
| PCSK6-214 | PCSK6 | P29122 | Proprotein convertase subtilisin/kexin type 6 | chr15 | GO:0004175 | Not Cancer Driver | No | 113 | 0.1166150670794633 | 207 | 41 | 0.0423116615067079 | 0 |
| PIDD1-201 | PIDD1 | Q9HB75 | p53-induced death domain-containing protein 1 | chr11 | GO:0004175 | Not Cancer Driver | No | 72 | 0.0791208791208791 | 140 | 9 | 0.0098901098901098 | 2 |
| PIK3IP1-201 | PIK3IP1 | Q96FE7 | Phosphoinositide-3-kinase-interacting protein 1 | chr22 | GO:0004175 | Not Cancer Driver | No | 16 | 0.0608365019011406 | 128 | 8 | 0.0304182509505703 | 0 |
| PLG-202 | PLG | P00747 | Plasminogen | chr6 | GO:0004175 | Not Cancer Driver | No | 190 | 0.2345679012345679 | 233 | 55 | 0.0679012345679012 | 9 |
| PSEN1-201 | PSEN1 | P49768 | Presenilin-1 | chr14 | GO:0004175 | Not Cancer Driver | No | 43 | 0.0920770877944325 | 134 | 18 | 0.038543897216274 | 69 |
| PSMA6-201 | PSMA6 | P60900 | Proteasome subunit alpha type-6 | chr14 | GO:0004175 | Not Cancer Driver | No | 33 | 0.1341463414634146 | 3 | 0 | 0.0 | 0 |
| PSMB10-201 | PSMB10 | P40306 | Proteasome subunit beta type-10 | chr16 | GO:0004175 | Not Cancer Driver | No | 15 | 0.0549450549450549 | 36 | 4 | 0.0146520146520146 | 0 |
| PSMB11-201 | PSMB11 | A5LHX3 | Proteasome subunit beta type-11 | chr14 | GO:0004175 | Not Cancer Driver | No | 41 | 0.1366666666666666 | 71 | 10 | 0.0333333333333333 | 0 |
| PSMB5-202 | PSMB5 | P28074 | Proteasome subunit beta type-5 | chr14 | GO:0004175 | Not Cancer Driver | No | 31 | 0.11787072243346 | 9 | 0 | 0.0 | 0 |
| PSMB6-201 | PSMB6 | P28072 | Proteasome subunit beta type-6 | chr17 | GO:0004175 | Not Cancer Driver | No | 16 | 0.0669456066945606 | 22 | 1 | 0.00418410041841 | 0 |
| PSMB7-201 | PSMB7 | Q99436 | Proteasome subunit beta type-7 | chr9 | GO:0004175 | Not Cancer Driver | No | 19 | 0.0685920577617328 | 26 | 3 | 0.0108303249097472 | 0 |
| PSMB8-202 | PSMB8 | P28062 | Proteasome subunit beta type-8 | chr6 | GO:0004175 | Not Cancer Driver | No | 34 | 0.1231884057971014 | 62 | 6 | 0.0217391304347826 | 3 |
| PSMB9-207 | PSMB9 | P28065 | Proteasome subunit beta type-9 | chr6 | GO:0004175 | Not Cancer Driver | No | 16 | 0.0730593607305936 | 17 | 1 | 0.0045662100456621 | 1 |
| RCE1-201 | RCE1 | Q9Y256 | CAAX prenyl protease 2 | chr11 | GO:0004175 | Not Cancer Driver | No | 26 | 0.0790273556231003 | 0 | 0 | 0.0 | 0 |
| SENP1-204 | SENP1 | Q9P0U3 | Sentrin-specific protease 1 | chr12 | GO:0004175 | Not Cancer Driver | No | 42 | 0.0652173913043478 | 355 | 31 | 0.0481366459627329 | 0 |
| SHH-201 | SHH | Q15465 | Sonic hedgehog protein | chr7 | GO:0004175 | Not Cancer Driver | No | 36 | 0.0779220779220779 | 139 | 11 | 0.0238095238095238 | 69 |
| TMEM59-201 | TMEM59 | Q9BXS4 | Transmembrane protein 59 | chr1 | GO:0004175 | Not Cancer Driver | No | 25 | 0.0773993808049535 | 26 | 2 | 0.0061919504643962 | 0 |
| TPP1-201 | TPP1 | O14773 | Tripeptidyl-peptidase 1 | chr11 | GO:0004175 | Not Cancer Driver | No | 56 | 0.0994671403197158 | 92 | 7 | 0.0124333925399644 | 34 |
| TPP2-202 | TPP2 | P29144 | Tripeptidyl-peptidase 2 | chr13 | GO:0004175 | Not Cancer Driver | No | 110 | 0.088070456365092 | 218 | 34 | 0.0272217774219375 | 1 |
| TRABD2A-203 | TRABD2A | Q86V40 | Metalloprotease TIKI1 | chr2 | GO:0004175 | Not Cancer Driver | No | 65 | 0.1287128712871287 | 133 | 29 | 0.0574257425742574 | 0 |