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Total number of protein in "GO:0004713" GO term:  94

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AATK-201 AATK Q6ZMQ8 Serine/threonine-protein kinase LMTK1 chr17 GO:0004713 Not Cancer Driver No 82 0.0596797671033478 916 59 0.0429403202328966 0
ABL1-201 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0004713 Census, Compendium Yes 106 0.0938053097345132 609 53 0.0469026548672566 2
ABL2-203 ABL2 P42684 Tyrosine-protein kinase ABL2 chr1 GO:0004713 Census, Compendium Yes 125 0.1057529610829103 644 53 0.0448392554991539 0
ALK-201 ALK Q9UM73 ALK tyrosine kinase receptor chr2 GO:0004713 Census, Compendium Yes 233 0.1438271604938271 577 79 0.0487654320987654 12
AXL-201 AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0004713 Not Cancer Driver No 131 0.1465324384787472 342 51 0.0570469798657718 0
BCR-201 BCR P11274 Breakpoint cluster region protein chr22 GO:0004713 Census, Compendium Yes 112 0.088119590873328 607 57 0.044846577498033 0
BLK-201 BLK P51451 Tyrosine-protein kinase Blk chr8 GO:0004713 Not Cancer Driver No 78 0.1544554455445544 75 17 0.0336633663366336 0
BMX-202 BMX P51813 Cytoplasmic tyrosine-protein kinase BMX chrX GO:0004713 Not Cancer Driver No 74 0.1096296296296296 172 16 0.0237037037037037 0
BTK-201 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0004713 Census, Compendium Yes 109 0.165402124430956 114 21 0.0318664643399089 83
CAMKK2-207 CAMKK2 Q96RR4 Calcium/calmodulin-dependent protein kinase kinase 2 chr12 GO:0004713 Not Cancer Driver No 45 0.0765306122448979 283 28 0.0476190476190476 0
CHKA-201 CHKA P35790 Choline kinase alpha chr11 GO:0004713 Not Cancer Driver No 31 0.0678336980306345 121 2 0.0043763676148796 3
CLK1-201 CLK1 P49759 Dual specificity protein kinase CLK1 chr2 GO:0004713 Not Cancer Driver No 51 0.1053719008264462 131 16 0.0330578512396694 0
CLK2-203 CLK2 P49760 Dual specificity protein kinase CLK2 chr1 GO:0004713 Not Cancer Driver No 76 0.1523046092184369 151 19 0.0380761523046092 0
CLK4-201 CLK4 Q9HAZ1 Dual specificity protein kinase CLK4 chr5 GO:0004713 Not Cancer Driver No 35 0.0727650727650727 102 8 0.0166320166320166 0
CSF1R-210 CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0004713 Census Yes 101 0.1039094650205761 124 12 0.0123456790123456 20
CSK-201 CSK P41240 Tyrosine-protein kinase CSK chr15 GO:0004713 Not Cancer Driver No 37 0.0822222222222222 18 1 0.0022222222222222 0
DSTYK-202 DSTYK Q6XUX3 Dual serine/threonine and tyrosine protein kinase chr1 GO:0004713 Not Cancer Driver No 88 0.0947255113024757 113 6 0.0064585575888051 2
DYRK1A-214 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 GO:0004713 Not Cancer Driver No 3 0.0039318479685452 447 1 0.001310615989515 0
DYRK1B-201 DYRK1B Q9Y463 Dual specificity tyrosine-phosphorylation-regulated kinase 1B chr19 GO:0004713 Not Cancer Driver No 67 0.1065182829888712 319 31 0.0492845786963434 2
DYRK2-202 DYRK2 Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 chr12 GO:0004713 Not Cancer Driver No 60 0.0998336106489184 294 33 0.0549084858569051 0
DYRK3-203 DYRK3 O43781 Dual specificity tyrosine-phosphorylation-regulated kinase 3 chr1 GO:0004713 Not Cancer Driver No 54 0.0918367346938775 193 11 0.0187074829931972 0
DYRK4-211 DYRK4 Q9NR20 Dual specificity tyrosine-phosphorylation-regulated kinase 4 chr12 GO:0004713 Not Cancer Driver No 86 0.1653846153846153 178 25 0.048076923076923 0
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 GO:0004713 Census, Compendium Yes 346 0.2859504132231405 223 30 0.024793388429752 1
EPHA4-201 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0004713 Not Cancer Driver No 132 0.1338742393509127 141 16 0.0162271805273833 0
EPHA7-202 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 GO:0004713 Census, Compendium Yes 226 0.2264529058116232 71 10 0.0100200400801603 0
EPHB2-204 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0004713 Not Cancer Driver No 149 0.1412322274881516 120 11 0.0104265402843601 7
ERBB2-201 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0004713 Census, Compendium Yes 249 0.198406374501992 315 32 0.0254980079681274 1
ERBB3-201 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:0004713 Census, Compendium Yes 265 0.1974664679582712 398 59 0.0439642324888226 3
ERBB4-202 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 GO:0004713 Census, Compendium Yes 376 0.2874617737003058 324 95 0.0726299694189602 2
FER-201 FER P16591 Tyrosine-protein kinase Fer chr5 GO:0004713 Not Cancer Driver No 70 0.0851581508515815 145 13 0.0158150851581508 0
FES-201 FES P07332 Tyrosine-protein kinase Fes/Fps chr15 GO:0004713 Census Yes 70 0.0851581508515815 246 24 0.0291970802919708 0
FGFR1-214 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 GO:0004713 Census, Compendium Yes 92 0.1119221411192214 231 26 0.0316301703163017 69
FGFR2-206 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0004713 Census, Compendium Yes 193 0.2350791717417783 229 34 0.0414129110840438 57
FGFR3-205 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 GO:0004713 Census, Compendium Yes 134 0.1662531017369727 241 18 0.0223325062034739 32
FGR-203 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:0004713 Not Cancer Driver No 67 0.1266540642722117 52 6 0.0113421550094517 0
FLT3-201 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0004713 Census, Compendium Yes 153 0.1540785498489426 64 19 0.0191339375629405 0
FRK-201 FRK P42685 Tyrosine-protein kinase FRK chr6 GO:0004713 Not Cancer Driver No 59 0.1168316831683168 18 2 0.0039603960396039 0
FYN-202 FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0004713 Not Cancer Driver No 64 0.1191806331471136 71 11 0.0204841713221601 0
HCK-202 HCK P08631 Tyrosine-protein kinase HCK chr20 GO:0004713 Not Cancer Driver No 89 0.1692015209125475 124 22 0.0418250950570342 0
HIPK1-208 HIPK1 Q86Z02 Homeodomain-interacting protein kinase 1 chr1 GO:0004713 Not Cancer Driver No 104 0.0859504132231405 567 58 0.0479338842975206 0
HIPK2-202 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:0004713 Not Cancer Driver No 124 0.1035058430717863 686 76 0.0634390651085141 0
HIPK3-201 HIPK3 Q9H422 Homeodomain-interacting protein kinase 3 chr11 GO:0004713 Not Cancer Driver No 91 0.0748971193415637 559 38 0.031275720164609 0
HIPK4-201 HIPK4 Q8NE63 Homeodomain-interacting protein kinase 4 chr19 GO:0004713 Not Cancer Driver No 65 0.1055194805194805 260 21 0.034090909090909 0
IGF1R-217 IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0004713 Not Cancer Driver No 143 0.1046086320409656 265 30 0.021945866861741 6
INSR-201 INSR P06213 Insulin receptor chr19 GO:0004713 Not Cancer Driver No 139 0.1005788712011577 282 37 0.0267727930535455 63
JAK1-201 JAK1 P23458 Tyrosine-protein kinase JAK1 chr1 GO:0004713 Census, Compendium Yes 109 0.0944540727902946 120 6 0.0051993067590987 2
JAK2-201 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0004713 Census, Compendium Yes 81 0.0715547703180212 59 4 0.0035335689045936 4
JAK3-201 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0004713 Census, Compendium Yes 131 0.1165480427046263 63 4 0.0035587188612099 7
KDR-201 KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0004713 Census, Compendium Yes 276 0.2035398230088495 276 40 0.0294985250737463 2
KIT-201 KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0004713 Census, Compendium Yes 186 0.1905737704918032 84 24 0.0245901639344262 15
LCK-202 LCK P06239 Tyrosine-protein kinase Lck chr1 GO:0004713 Census Yes 76 0.1493123772102161 95 12 0.0235756385068762 1
LTK-201 LTK P29376 Leukocyte tyrosine kinase receptor chr15 GO:0004713 Not Cancer Driver No 63 0.0729166666666666 301 17 0.0196759259259259 0
LYN-202 LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0004713 Census Yes 78 0.15234375 85 10 0.01953125 0
MAP2K1-201 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 GO:0004713 Census, Compendium Yes 83 0.2111959287531806 96 22 0.0559796437659033 5
MAP2K2-201 MAP2K2 P36507 Dual specificity mitogen-activated protein kinase kinase 2 chr19 GO:0004713 Census Yes 45 0.1125 107 13 0.0325 3
MAP2K3-202 MAP2K3 P46734 Dual specificity mitogen-activated protein kinase kinase 3 chr17 GO:0004713 Not Cancer Driver No 74 0.2132564841498559 76 19 0.0547550432276657 0
MAP2K4-201 MAP2K4 P45985 Dual specificity mitogen-activated protein kinase kinase 4 chr17 GO:0004713 Census, Compendium Yes 72 0.1804511278195488 137 23 0.0576441102756892 0
MAP2K5-201 MAP2K5 Q13163 Dual specificity mitogen-activated protein kinase kinase 5 chr15 GO:0004713 Not Cancer Driver No 26 0.0580357142857142 85 6 0.0133928571428571 0
MAP2K6-206 MAP2K6 P52564 Dual specificity mitogen-activated protein kinase kinase 6 chr17 GO:0004713 Not Cancer Driver No 28 0.0838323353293413 55 6 0.0179640718562874 0
MAP2K7-201 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0004713 Compendium Yes 78 0.1861575178997613 145 17 0.0405727923627685 0
MATK-201 MATK P42679 Megakaryocyte-associated tyrosine-protein kinase chr19 GO:0004713 Not Cancer Driver No 69 0.136094674556213 146 26 0.0512820512820512 0
MET-202 MET P08581 Hepatocyte growth factor receptor chr7 GO:0004713 Census, Compendium Yes 161 0.1158273381294964 62 10 0.0071942446043165 16
MUSK-204 MUSK O15146 Muscle, skeletal receptor tyrosine-protein kinase chr9 GO:0004713 Not Cancer Driver No 145 0.1668584579976985 35 7 0.0080552359033371 7
NEK1-201 NEK1 Q96PY6 Serine/threonine-protein kinase Nek1 chr4 GO:0004713 Not Cancer Driver No 78 0.0620031796502384 882 60 0.0476947535771065 3
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0004713 Census, Compendium Yes 133 0.1670854271356784 57 8 0.0100502512562814 23
PBK-201 PBK Q96KB5 Lymphokine-activated killer T-cell-originated protein kinase chr8 GO:0004713 Not Cancer Driver No 16 0.0496894409937888 92 6 0.0186335403726708 0
PDGFRB-201 PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0004713 Census, Compendium Yes 134 0.1211573236889692 233 40 0.0361663652802893 7
PKM-202 PKM P14618 Pyruvate kinase PKM chr15 GO:0004713 Not Cancer Driver No 53 0.0998116760828625 58 11 0.0207156308851224 0
PTK2-228 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0004713 Not Cancer Driver No 102 0.0969581749049429 426 45 0.0427756653992395 0
PTK2B-201 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0004713 Not Cancer Driver No 117 0.1159563924677899 263 23 0.0227948463825569 0
PTK6-202 PTK6 Q13882 Protein-tyrosine kinase 6 chr20 GO:0004713 Census Yes 31 0.0687361419068736 12 0 0.0 0
RET-202 RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0004713 Census, Compendium Yes 176 0.1579892280071813 108 11 0.0098743267504488 91
ROS1-202 ROS1 P08922 Proto-oncogene tyrosine-protein kinase ROS chr6 GO:0004713 Census Yes 356 0.1516829995739241 197 45 0.0191734128674904 0
RPS6KA5-207 RPS6KA5 O75582 Ribosomal protein S6 kinase alpha-5 chr14 GO:0004713 Not Cancer Driver No 79 0.098503740648379 187 17 0.0211970074812967 0
RYK-208 RYK P34925 Tyrosine-protein kinase RYK chr3 GO:0004713 Not Cancer Driver No 38 0.0626029654036243 85 3 0.0049423393739703 0
SCYL1-201 SCYL1 Q96KG9 N-terminal kinase-like protein chr11 GO:0004713 Not Cancer Driver No 58 0.0717821782178217 312 23 0.0284653465346534 0
SRC-204 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0004713 Census Yes 40 0.0746268656716417 130 10 0.0186567164179104 1
SRMS-201 SRMS Q9H3Y6 Tyrosine-protein kinase Srms chr20 GO:0004713 Not Cancer Driver No 56 0.1147540983606557 48 7 0.0143442622950819 0
STYK1-201 STYK1 Q6J9G0 Tyrosine-protein kinase STYK1 chr12 GO:0004713 Not Cancer Driver No 67 0.1587677725118483 35 7 0.0165876777251184 0
SYK-204 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0004713 Census Yes 75 0.1181102362204724 131 20 0.0314960629921259 4
TESK1-201 TESK1 Q15569 Dual specificity testis-specific protein kinase 1 chr9 GO:0004713 Not Cancer Driver No 51 0.0814696485623003 340 27 0.0431309904153354 0
TESK2-202 TESK2 Q96S53 Dual specificity testis-specific protein kinase 2 chr1 GO:0004713 Not Cancer Driver No 57 0.0998248686514886 243 31 0.0542907180385289 0
TNK1-207 TNK1 Q13470 Non-receptor tyrosine-protein kinase TNK1 chr17 GO:0004713 Not Cancer Driver No 42 0.063063063063063 298 23 0.0345345345345345 0
TNK2-201 TNK2 Q07912 Activated CDC42 kinase 1 chr3 GO:0004713 Not Cancer Driver No 103 0.0992292870905587 598 66 0.0635838150289017 0
TTBK1-201 TTBK1 Q5TCY1 Tau-tubulin kinase 1 chr6 GO:0004713 Not Cancer Driver No 151 0.1143073429220287 1047 114 0.0862982588947766 0
TTK-202 TTK P33981 Dual specificity protein kinase TTK chr6 GO:0004713 Not Cancer Driver No 106 0.1236872812135355 354 40 0.0466744457409568 0
TTN-215 TTN Q8WZ42 Titin chr2 GO:0004713 Not Cancer Driver No 3472 0.1010771470160116 12945 1338 0.0389519650655021 10
TWF1-201 TWF1 Q12792 Twinfilin-1 chr12 GO:0004713 Not Cancer Driver No 25 0.0714285714285714 52 1 0.0028571428571428 0
TYK2-204 TYK2 P29597 Non-receptor tyrosine-protein kinase TYK2 chr19 GO:0004713 Not Cancer Driver No 118 0.0994102780117944 213 20 0.016849199663016 0
TYRO3-201 TYRO3 Q06418 Tyrosine-protein kinase receptor TYRO3 chr15 GO:0004713 Not Cancer Driver No 86 0.096629213483146 197 18 0.0202247191011235 0
WEE1-202 WEE1 P30291 Wee1-like protein kinase chr11 GO:0004713 Not Cancer Driver No 42 0.0650154798761609 399 20 0.0309597523219814 0
WEE2-201 WEE2 P0C1S8 Wee1-like protein kinase 2 chr7 GO:0004713 Not Cancer Driver No 72 0.1269841269841269 345 44 0.0776014109347442 1
YES1-201 YES1 P07947 Tyrosine-protein kinase Yes chr18 GO:0004713 Not Cancer Driver No 48 0.0883977900552486 63 9 0.0165745856353591 0
ZAP70-201 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 GO:0004713 Not Cancer Driver No 90 0.1453957996768982 119 13 0.0210016155088853 7