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Total number of protein in "GO:0004842" GO term:  220

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AMFR-201 AMFR Q9UKV5 E3 ubiquitin-protein ligase AMFR chr16 GO:0004842 Not Cancer Driver No 49 0.0762052877138413 229 22 0.0342146189735614 0
ANAPC11-201 ANAPC11 Q9NYG5 Anaphase-promoting complex subunit 11 chr17 GO:0004842 Not Cancer Driver No 1 0.0119047619047619 0 0 0.0 0
ANAPC4-201 ANAPC4 Q9UJX5 Anaphase-promoting complex subunit 4 chr4 GO:0004842 Not Cancer Driver No 48 0.0594059405940594 54 0 0.0 0
AREL1-201 AREL1 O15033 Apoptosis-resistant E3 ubiquitin protein ligase 1 chr14 GO:0004842 Not Cancer Driver No 70 0.0850546780072904 92 8 0.0097205346294046 0
ARIH1-201 ARIH1 Q9Y4X5 E3 ubiquitin-protein ligase ARIH1 chr15 GO:0004842 Not Cancer Driver No 27 0.0484739676840215 119 1 0.0017953321364452 2
ARIH2-201 ARIH2 O95376 E3 ubiquitin-protein ligase ARIH2 chr3 GO:0004842 Not Cancer Driver No 45 0.0912778904665314 85 9 0.0182555780933062 0
ASB4-202 ASB4 Q9Y574 Ankyrin repeat and SOCS box protein 4 chr7 GO:0004842 Not Cancer Driver No 60 0.1408450704225352 19 1 0.0023474178403755 0
BARD1-201 BARD1 Q99728 BRCA1-associated RING domain protein 1 chr2 GO:0004842 Census Yes 71 0.0913770913770913 390 39 0.0501930501930501 0
BCOR-202 BCOR Q6W2J9 BCL-6 corepressor chrX GO:0004842 Census, Compendium Yes 219 0.1247863247863247 1289 174 0.0991452991452991 1
BIRC2-201 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 GO:0004842 Not Cancer Driver No 49 0.0792880258899676 85 7 0.0113268608414239 0
BIRC3-201 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 GO:0004842 Census, Compendium Yes 53 0.0877483443708609 98 10 0.0165562913907284 0
BIRC6-201 BIRC6 Q9NR09 Baculoviral IAP repeat-containing protein 6 chr2 GO:0004842 Census, Compendium Yes 468 0.0963557751698579 1314 124 0.0255301626518427 0
BIRC7-201 BIRC7 Q96CA5 Baculoviral IAP repeat-containing protein 7 chr20 GO:0004842 Not Cancer Driver No 45 0.1510067114093959 138 18 0.0604026845637583 0
BRAP-202 BRAP Q7Z569 BRCA1-associated protein chr12 GO:0004842 Not Cancer Driver No 54 0.0912162162162162 193 16 0.027027027027027 0
BRCA1-203 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0004842 Census, Compendium Yes 167 0.0896403650026838 1466 127 0.0681696188942565 34
CBL-201 CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0004842 Census, Compendium Yes 84 0.0927152317880794 513 44 0.0485651214128035 4
CBLL1-205 CBLL1 Q75N03 E3 ubiquitin-protein ligase Hakai chr7 GO:0004842 Not Cancer Driver No 56 0.1140529531568228 373 39 0.0794297352342158 0
CDC23-202 CDC23 Q9UJX2 Cell division cycle protein 23 homolog chr5 GO:0004842 Not Cancer Driver No 35 0.0586264656616415 45 4 0.0067001675041876 0
CDC34-201 CDC34 P49427 Ubiquitin-conjugating enzyme E2 R1 chr19 GO:0004842 Not Cancer Driver No 19 0.0805084745762711 96 7 0.0296610169491525 0
CHFR-203 CHFR Q96EP1 E3 ubiquitin-protein ligase CHFR chr12 GO:0004842 Not Cancer Driver No 59 0.0888554216867469 342 37 0.055722891566265 0
CNOT4-214 CNOT4 O95628 CCR4-NOT transcription complex subunit 4 chr7 GO:0004842 Not Cancer Driver No 46 0.08 360 24 0.0417391304347826 0
COP1-204 COP1 Q8NHY2 E3 ubiquitin-protein ligase COP1 chr1 GO:0004842 Not Cancer Driver No 81 0.1108071135430916 148 5 0.0068399452804377 0
CUL2-203 CUL2 Q13617 Cullin-2 chr10 GO:0004842 Not Cancer Driver No 64 0.0859060402684563 66 2 0.0026845637583892 0
CUL3-201 CUL3 Q13618 Cullin-3 chr2 GO:0004842 Census, Compendium Yes 98 0.1276041666666666 168 18 0.0234375 3
CUL5-201 CUL5 Q93034 Cullin-5 chr11 GO:0004842 Not Cancer Driver No 69 0.0884615384615384 5 1 0.0012820512820512 0
DDB2-201 DDB2 Q92466 DNA damage-binding protein 2 chr11 GO:0004842 Census, Compendium Yes 35 0.081967213114754 71 5 0.0117096018735363 2
DTL-201 DTL Q9NZJ0 Denticleless protein homolog chr1 GO:0004842 Not Cancer Driver No 53 0.0726027397260273 333 38 0.0520547945205479 0
DTX3L-201 DTX3L Q8TDB6 E3 ubiquitin-protein ligase DTX3L chr3 GO:0004842 Not Cancer Driver No 60 0.081081081081081 260 19 0.0256756756756756 0
DTX4-201 DTX4 Q9Y2E6 E3 ubiquitin-protein ligase DTX4 chr11 GO:0004842 Not Cancer Driver No 59 0.0953150242326332 326 39 0.0630048465266559 0
DZIP3-201 DZIP3 Q86Y13 E3 ubiquitin-protein ligase DZIP3 chr3 GO:0004842 Not Cancer Driver No 141 0.1167218543046357 372 55 0.0455298013245033 0
ENST00000358757 UBE2W Q96B02 Ubiquitin-conjugating enzyme E2 W chr8 GO:0004842 Not Cancer Driver No 12 0.0745341614906832 26 3 0.0186335403726708 0
ENST00000558468 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 GO:0004842 Not Cancer Driver No 116 0.1082089552238805 320 38 0.0354477611940298 0
ENST00000648873 RNF43 Q68DV7 E3 ubiquitin-protein ligase RNF43 chr17 GO:0004842 Census, Compendium Yes 99 0.127906976744186 414 42 0.0542635658914728 0
ENST00000674680 TRIM2 Q9C040 Tripartite motif-containing protein 2 chr4 GO:0004842 Not Cancer Driver No 0 0.0 0 0 0.0 0
ERCC8-218 ERCC8 Q13216 DNA excision repair protein ERCC-8 chr5 GO:0004842 Not Cancer Driver No 17 0.0429292929292929 55 7 0.0176767676767676 6
FANCL-201 FANCL Q9NW38 E3 ubiquitin-protein ligase FANCL chr2 GO:0004842 Not Cancer Driver No 39 0.104 11 1 0.0026666666666666 0
FBXL14-201 FBXL14 Q8N1E6 F-box/LRR-repeat protein 14 chr12 GO:0004842 Not Cancer Driver No 27 0.0645933014354067 7 1 0.0023923444976076 0
FBXL3-201 FBXL3 Q9UKT7 F-box/LRR-repeat protein 3 chr13 GO:0004842 Not Cancer Driver No 24 0.0560747663551401 30 5 0.0116822429906542 1
FBXL5-201 FBXL5 Q9UKA1 F-box/LRR-repeat protein 5 chr4 GO:0004842 Not Cancer Driver No 50 0.0723589001447178 71 4 0.0057887120115774 0
FBXL6-201 FBXL6 Q8N531 F-box/LRR-repeat protein 6 chr8 GO:0004842 Not Cancer Driver No 30 0.0556586270871985 114 5 0.0092764378478664 0
FBXO10-202 FBXO10 Q9UK96 F-box only protein 10 chr9 GO:0004842 Not Cancer Driver No 91 0.0951882845188284 224 17 0.0177824267782426 0
FBXO11-202 FBXO11 Q86XK2 F-box only protein 11 chr2 GO:0004842 Census, Compendium Yes 85 0.0916936353829557 242 17 0.0183387270765911 8
FBXO2-201 FBXO2 Q9UK22 F-box only protein 2 chr1 GO:0004842 Not Cancer Driver No 16 0.054054054054054 76 0 0.0 0
FBXO21-201 FBXO21 O94952 F-box only protein 21 chr12 GO:0004842 Not Cancer Driver No 53 0.0843949044585987 18 3 0.0047770700636942 0
FBXO22-201 FBXO22 Q8NEZ5 F-box only protein 22 chr15 GO:0004842 Not Cancer Driver No 43 0.1066997518610421 15 1 0.0024813895781637 0
FBXO24-201 FBXO24 O75426 F-box only protein 24 chr7 GO:0004842 Not Cancer Driver No 88 0.1517241379310344 55 9 0.0155172413793103 0
FBXO25-204 FBXO25 Q8TCJ0 F-box only protein 25 chr8 GO:0004842 Not Cancer Driver No 23 0.0626702997275204 21 0 0.0 0
FBXO3-201 FBXO3 Q9UK99 F-box only protein 3 chr11 GO:0004842 Not Cancer Driver No 32 0.0679405520169851 51 2 0.0042462845010615 0
FBXO4-201 FBXO4 Q9UKT5 F-box only protein 4 chr5 GO:0004842 Not Cancer Driver No 38 0.0981912144702842 68 6 0.0155038759689922 0
FBXO7-201 FBXO7 Q9Y3I1 F-box only protein 7 chr22 GO:0004842 Not Cancer Driver No 49 0.0938697318007662 243 24 0.0459770114942528 1
FBXO9-201 FBXO9 Q9UK97 F-box only protein 9 chr6 GO:0004842 Not Cancer Driver No 34 0.076062639821029 110 7 0.0156599552572706 0
FBXW2-203 FBXW2 Q9UKT8 F-box/WD repeat-containing protein 2 chr9 GO:0004842 Not Cancer Driver No 35 0.0770925110132158 0 0 0.0 0
FBXW8-204 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 GO:0004842 Not Cancer Driver No 48 0.0802675585284281 121 4 0.0066889632107023 0
G2E3-201 G2E3 Q7L622 G2/M phase-specific E3 ubiquitin-protein ligase chr14 GO:0004842 Not Cancer Driver No 55 0.0779036827195467 26 6 0.0084985835694051 0
HACE1-201 HACE1 Q8IYU2 E3 ubiquitin-protein ligase HACE1 chr6 GO:0004842 Not Cancer Driver No 93 0.1023102310231023 103 10 0.011001100110011 0
HECTD3-202 HECTD3 Q5T447 E3 ubiquitin-protein ligase HECTD3 chr1 GO:0004842 Not Cancer Driver No 66 0.0766550522648083 55 3 0.0034843205574912 0
HECTD4-216 HECTD4 Q9Y4D8 Probable E3 ubiquitin-protein ligase HECTD4 chr12 GO:0004842 Not Cancer Driver No 364 0.0823902218198279 1064 103 0.0233137166138524 0
HERC1-201 HERC1 Q15751 Probable E3 ubiquitin-protein ligase HERC1 chr15 GO:0004842 Not Cancer Driver No 350 0.0720016457519029 1353 102 0.0209833367619831 1
HERC5-201 HERC5 Q9UII4 E3 ISG15--protein ligase HERC5 chr4 GO:0004842 Not Cancer Driver No 77 0.0751953125 119 7 0.0068359375 0
HUWE1-202 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX GO:0004842 Not Cancer Driver No 263 0.0601280292638317 2091 107 0.0244627343392775 20
ITCH-201 ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0004842 Not Cancer Driver No 75 0.0830564784053156 335 33 0.0365448504983388 0
KCTD10-201 KCTD10 Q9H3F6 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 chr12 GO:0004842 Not Cancer Driver No 47 0.1501597444089457 73 11 0.0351437699680511 0
KCTD13-208 KCTD13 Q8WZ19 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 chr16 GO:0004842 Not Cancer Driver No 27 0.0820668693009118 95 6 0.0182370820668693 0
KLHL13-201 KLHL13 Q9P2N7 Kelch-like protein 13 chrX GO:0004842 Not Cancer Driver No 119 0.181679389312977 51 14 0.0213740458015267 0
KLHL20-201 KLHL20 Q9Y2M5 Kelch-like protein 20 chr1 GO:0004842 Not Cancer Driver No 64 0.1050903119868637 144 12 0.0197044334975369 0
KLHL21-201 KLHL21 Q9UJP4 Kelch-like protein 21 chr1 GO:0004842 Not Cancer Driver No 34 0.0569514237855946 63 7 0.0117252931323283 0
KLHL42-201 KLHL42 Q9P2K6 Kelch-like protein 42 chr12 GO:0004842 Not Cancer Driver No 38 0.0752475247524752 57 4 0.0079207920792079 0
KLHL9-201 KLHL9 Q9P2J3 Kelch-like protein 9 chr9 GO:0004842 Not Cancer Driver No 47 0.0761750405186385 26 3 0.0048622366288492 0
LMO7-205 LMO7 Q8WWI1 LIM domain only protein 7 chr13 GO:0004842 Not Cancer Driver No 134 0.082158185162477 1117 116 0.0711220110361741 0
LNX1-201 LNX1 Q8TBB1 E3 ubiquitin-protein ligase LNX chr4 GO:0004842 Not Cancer Driver No 90 0.1236263736263736 261 33 0.0453296703296703 0
LNX2-201 LNX2 Q8N448 Ligand of Numb protein X 2 chr13 GO:0004842 Not Cancer Driver No 58 0.0840579710144927 277 25 0.036231884057971 0
LRSAM1-201 LRSAM1 Q6UWE0 E3 ubiquitin-protein ligase LRSAM1 chr9 GO:0004842 Not Cancer Driver No 71 0.0982019363762102 240 24 0.0331950207468879 1
MAEA-202 MAEA Q7L5Y9 E3 ubiquitin-protein transferase MAEA chr4 GO:0004842 Not Cancer Driver No 50 0.1262626262626262 64 5 0.0126262626262626 0
MAGEL2-201 MAGEL2 Q9UJ55 MAGE-like protein 2 chr15 GO:0004842 Not Cancer Driver No 157 0.1257005604483587 1010 104 0.0832666132906325 0
MALT1-208 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0004842 Census, Compendium Yes 55 0.0667475728155339 139 9 0.0109223300970873 1
MARCHF11-201 MARCHF11 A6NNE9 E3 ubiquitin-protein ligase MARCHF11 chr5 GO:0004842 Not Cancer Driver No 73 0.181592039800995 177 5 0.0124378109452736 0
MARCHF2-201 MARCHF2 Q9P0N8 E3 ubiquitin-protein ligase MARCHF2 chr19 GO:0004842 Not Cancer Driver No 24 0.0975609756097561 23 2 0.008130081300813 0
MARCHF3-201 MARCHF3 Q86UD3 E3 ubiquitin-protein ligase MARCHF3 chr5 GO:0004842 Not Cancer Driver No 20 0.0790513833992094 5 1 0.0039525691699604 0
MARCHF4-201 MARCHF4 Q9P2E8 E3 ubiquitin-protein ligase MARCHF4 chr2 GO:0004842 Not Cancer Driver No 77 0.1878048780487805 155 26 0.0634146341463414 0
MARCHF6-201 MARCHF6 O60337 E3 ubiquitin-protein ligase MARCHF6 chr5 GO:0004842 Not Cancer Driver No 87 0.0956043956043956 114 10 0.0109890109890109 0
MARCHF8-201 MARCHF8 Q5T0T0 E3 ubiquitin-protein ligase MARCHF8 chr10 GO:0004842 Not Cancer Driver No 25 0.0859106529209622 71 8 0.0274914089347079 0
MARCHF9-201 MARCHF9 Q86YJ5 E3 ubiquitin-protein ligase MARCHF9 chr12 GO:0004842 Not Cancer Driver No 19 0.0549132947976878 140 7 0.0202312138728323 0
MDM2-224 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0004842 Census, Compendium Yes 39 0.0794297352342158 298 24 0.0488798370672097 0
MDM4-203 MDM4 O15151 Protein Mdm4 chr1 GO:0004842 Census, Compendium Yes 33 0.0673469387755102 203 15 0.0306122448979591 1
MGRN1-202 MGRN1 O60291 E3 ubiquitin-protein ligase MGRN1 chr16 GO:0004842 Not Cancer Driver No 52 0.0942028985507246 228 28 0.0507246376811594 0
MIB1-201 MIB1 Q86YT6 E3 ubiquitin-protein ligase MIB1 chr18 GO:0004842 Not Cancer Driver No 96 0.0954274353876739 284 26 0.025844930417495 1
MIB2-201 MIB2 Q96AX9 E3 ubiquitin-protein ligase MIB2 chr1 GO:0004842 Not Cancer Driver No 64 0.0670157068062827 309 14 0.0146596858638743 0
MUL1-201 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 GO:0004842 Not Cancer Driver No 29 0.0823863636363636 16 2 0.0056818181818181 0
MYLIP-202 MYLIP Q8WY64 E3 ubiquitin-protein ligase MYLIP chr6 GO:0004842 Not Cancer Driver No 41 0.0921348314606741 11 2 0.0044943820224719 0
NEDD4L-205 NEDD4L Q96PU5 E3 ubiquitin-protein ligase NEDD4-like chr18 GO:0004842 Not Cancer Driver No 99 0.1015384615384615 463 44 0.0451282051282051 4
NEURL1-201 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0004842 Not Cancer Driver No 50 0.0871080139372822 153 10 0.0174216027874564 0
NHLRC1-201 NHLRC1 Q6VVB1 E3 ubiquitin-protein ligase NHLRC1 chr6 GO:0004842 Not Cancer Driver No 52 0.1316455696202531 18 3 0.0075949367088607 22
NSMCE1-201 NSMCE1 Q8WV22 Non-structural maintenance of chromosomes element 1 homolog chr16 GO:0004842 Not Cancer Driver No 21 0.0789473684210526 31 2 0.0075187969924812 0
OBI1-201 OBI1 Q5W0B1 ORC ubiquitin ligase 1 chr13 GO:0004842 Not Cancer Driver No 64 0.0881542699724518 486 43 0.059228650137741 0
PDZRN3-201 PDZRN3 Q9UPQ7 E3 ubiquitin-protein ligase PDZRN3 chr3 GO:0004842 Not Cancer Driver No 186 0.174484052532833 704 155 0.1454033771106941 0
PEX12-201 PEX12 O00623 Peroxisome assembly protein 12 chr17 GO:0004842 Not Cancer Driver No 29 0.0807799442896936 30 2 0.0055710306406685 1
PJA2-201 PJA2 O43164 E3 ubiquitin-protein ligase Praja-2 chr5 GO:0004842 Not Cancer Driver No 60 0.0847457627118644 601 50 0.0706214689265536 0
PRKN-206 PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0004842 Not Cancer Driver No 96 0.2064516129032258 78 14 0.0301075268817204 30
PRPF19-201 PRPF19 Q9UMS4 Pre-mRNA-processing factor 19 chr11 GO:0004842 Not Cancer Driver No 43 0.0853174603174603 110 12 0.0238095238095238 0
RAG1-201 RAG1 P15918 V(D)J recombination-activating protein 1 chr11 GO:0004842 Not Cancer Driver No 161 0.1543624161073825 209 34 0.0325982742090124 35
RBBP6-201 RBBP6 Q7Z6E9 E3 ubiquitin-protein ligase RBBP6 chr16 GO:0004842 Not Cancer Driver No 87 0.0485491071428571 1627 85 0.0474330357142857 0
RBCK1-202 RBCK1 Q9BYM8 RanBP-type and C3HC4-type zinc finger-containing protein 1 chr20 GO:0004842 Not Cancer Driver No 42 0.0823529411764705 141 14 0.0274509803921568 2
RBX1-201 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 GO:0004842 Not Cancer Driver No 9 0.0833333333333333 18 1 0.0092592592592592 0
RC3H1-203 RC3H1 Q5TC82 Roquin-1 chr1 GO:0004842 Not Cancer Driver No 114 0.1006178287731685 798 81 0.0714916151809355 0
RCHY1-201 RCHY1 Q96PM5 RING finger and CHY zinc finger domain-containing protein 1 chr4 GO:0004842 Not Cancer Driver No 18 0.0689655172413793 23 0 0.0 0
RLIM-201 RLIM Q9NVW2 E3 ubiquitin-protein ligase RLIM chrX GO:0004842 Not Cancer Driver No 78 0.125 548 69 0.110576923076923 4
RMND5A-201 RMND5A Q9H871 E3 ubiquitin-protein transferase RMND5A chr2 GO:0004842 Not Cancer Driver No 26 0.0664961636828644 0 0 0.0 0
RMND5B-201 RMND5B Q96G75 E3 ubiquitin-protein transferase RMND5B chr5 GO:0004842 Not Cancer Driver No 31 0.0788804071246819 0 0 0.0 0
RNF103-201 RNF103 O00237 E3 ubiquitin-protein ligase RNF103 chr2 GO:0004842 Not Cancer Driver No 50 0.072992700729927 65 5 0.0072992700729927 0
RNF115-202 RNF115 Q9Y4L5 E3 ubiquitin-protein ligase RNF115 chr1 GO:0004842 Not Cancer Driver No 23 0.0756578947368421 136 11 0.0361842105263157 0
RNF123-201 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 GO:0004842 Not Cancer Driver No 126 0.0958904109589041 220 23 0.017503805175038 0
RNF13-203 RNF13 O43567 E3 ubiquitin-protein ligase RNF13 chr3 GO:0004842 Not Cancer Driver No 27 0.0708661417322834 108 13 0.0341207349081364 2
RNF130-205 RNF130 Q86XS8 E3 ubiquitin-protein ligase RNF130 chr5 GO:0004842 Not Cancer Driver No 32 0.0763723150357995 43 2 0.0047732696897374 0
RNF135-202 RNF135 Q8IUD6 E3 ubiquitin-protein ligase RNF135 chr17 GO:0004842 Not Cancer Driver No 28 0.0648148148148148 139 5 0.011574074074074 0
RNF139-201 RNF139 Q8WU17 E3 ubiquitin-protein ligase RNF139 chr8 GO:0004842 Not Cancer Driver No 45 0.0677710843373494 68 3 0.0045180722891566 0
RNF141-201 RNF141 Q8WVD5 RING finger protein 141 chr11 GO:0004842 Not Cancer Driver No 21 0.0913043478260869 48 3 0.0130434782608695 0
RNF144B-201 RNF144B Q7Z419 E3 ubiquitin-protein ligase RNF144B chr6 GO:0004842 Not Cancer Driver No 30 0.099009900990099 4 1 0.0033003300330033 0
RNF146-202 RNF146 Q9NTX7 E3 ubiquitin-protein ligase RNF146 chr6 GO:0004842 Not Cancer Driver No 23 0.064066852367688 206 15 0.0417827298050139 0
RNF152-201 RNF152 Q8N8N0 E3 ubiquitin-protein ligase RNF152 chr18 GO:0004842 Not Cancer Driver No 57 0.2807881773399014 34 9 0.0443349753694581 0
RNF167-201 RNF167 Q9H6Y7 E3 ubiquitin-protein ligase RNF167 chr17 GO:0004842 Not Cancer Driver No 27 0.0771428571428571 102 13 0.0371428571428571 0
RNF168-201 RNF168 Q8IYW5 E3 ubiquitin-protein ligase RNF168 chr3 GO:0004842 Not Cancer Driver No 66 0.1155866900175131 473 56 0.0980735551663747 0
RNF169-201 RNF169 Q8NCN4 E3 ubiquitin-protein ligase RNF169 chr11 GO:0004842 Not Cancer Driver No 41 0.057909604519774 638 40 0.0564971751412429 0
RNF181-201 RNF181 Q9P0P0 E3 ubiquitin-protein ligase RNF181 chr2 GO:0004842 Not Cancer Driver No 13 0.0849673202614379 64 6 0.0392156862745098 0
RNF182-204 RNF182 Q8N6D2 E3 ubiquitin-protein ligase RNF182 chr6 GO:0004842 Not Cancer Driver No 35 0.1417004048582996 12 2 0.0080971659919028 0
RNF186-201 RNF186 Q9NXI6 E3 ubiquitin-protein ligase RNF186 chr1 GO:0004842 Not Cancer Driver No 19 0.0837004405286343 11 0 0.0 0
RNF187-201 RNF187 Q5TA31 E3 ubiquitin-protein ligase RNF187 chr1 GO:0004842 Not Cancer Driver No 0 0.0 104 0 0.0 0
RNF2-202 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 GO:0004842 Not Cancer Driver No 26 0.0773809523809523 203 15 0.0446428571428571 1
RNF20-202 RNF20 Q5VTR2 E3 ubiquitin-protein ligase BRE1A chr9 GO:0004842 Not Cancer Driver No 83 0.0851282051282051 563 43 0.0441025641025641 0
RNF208-201 RNF208 Q9H0X6 RING finger protein 208 chr9 GO:0004842 Not Cancer Driver No 16 0.0613026819923371 114 6 0.0229885057471264 0
RNF213-220 RNF213 Q63HN8 E3 ubiquitin-protein ligase RNF213 chr17 GO:0004842 Census, Compendium Yes 408 0.0783560591511426 628 60 0.011522949875168 3
RNF214-201 RNF214 Q8ND24 RING finger protein 214 chr11 GO:0004842 Not Cancer Driver No 52 0.0739687055476529 527 37 0.0526315789473684 0
RNF217-210 RNF217 Q8TC41 E3 ubiquitin-protein ligase RNF217 chr6 GO:0004842 Not Cancer Driver No 30 0.055350553505535 204 0 0.0 0
RNF220-203 RNF220 Q5VTB9 E3 ubiquitin-protein ligase RNF220 chr1 GO:0004842 Not Cancer Driver No 72 0.127208480565371 402 48 0.0848056537102473 2
RNF25-201 RNF25 Q96BH1 E3 ubiquitin-protein ligase RNF25 chr2 GO:0004842 Not Cancer Driver No 45 0.0980392156862745 289 34 0.074074074074074 0
RNF31-201 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 GO:0004842 Not Cancer Driver No 116 0.1082089552238805 319 38 0.0354477611940298 0
RNF4-201 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 GO:0004842 Not Cancer Driver No 9 0.0473684210526315 120 5 0.0263157894736842 0
RNF40-201 RNF40 O75150 E3 ubiquitin-protein ligase BRE1B chr16 GO:0004842 Not Cancer Driver No 102 0.1018981018981019 645 70 0.0699300699300699 0
RNF41-201 RNF41 Q9H4P4 E3 ubiquitin-protein ligase NRDP1 chr12 GO:0004842 Not Cancer Driver No 36 0.113564668769716 33 2 0.0063091482649842 0
RNF43-201 RNF43 Q68DV7 E3 ubiquitin-protein ligase RNF43 chr17 GO:0004842 Census, Compendium Yes 99 0.1264367816091954 440 46 0.0587484035759897 0
RNF5-203 RNF5 Q99942 E3 ubiquitin-protein ligase RNF5 chr6 GO:0004842 Not Cancer Driver No 12 0.0666666666666666 69 1 0.0055555555555555 0
RNF6-203 RNF6 Q9Y252 E3 ubiquitin-protein ligase RNF6 chr13 GO:0004842 Compendium Yes 54 0.0788321167883211 607 50 0.072992700729927 0
RNF8-202 RNF8 O76064 E3 ubiquitin-protein ligase RNF8 chr6 GO:0004842 Not Cancer Driver No 31 0.0639175257731958 226 14 0.0288659793814433 0
RSPRY1-201 RSPRY1 Q96DX4 RING finger and SPRY domain-containing protein 1 chr16 GO:0004842 Not Cancer Driver No 59 0.1024305555555555 98 17 0.0295138888888888 1
SHARPIN-202 SHARPIN Q9H0F6 Sharpin chr8 GO:0004842 Not Cancer Driver No 29 0.0749354005167958 237 13 0.0335917312661498 0
SHPRH-201 SHPRH Q149N8 E3 ubiquitin-protein ligase SHPRH chr6 GO:0004842 Not Cancer Driver No 173 0.1027926322043969 362 45 0.0267379679144385 0
SIAH1-203 SIAH1 Q8IUQ4 E3 ubiquitin-protein ligase SIAH1 chr16 GO:0004842 Not Cancer Driver No 22 0.0780141843971631 28 2 0.0070921985815602 5
SIAH2-201 SIAH2 O43255 E3 ubiquitin-protein ligase SIAH2 chr3 GO:0004842 Not Cancer Driver No 34 0.1049382716049382 68 2 0.0061728395061728 0
SMURF1-201 SMURF1 Q9HCE7 E3 ubiquitin-protein ligase SMURF1 chr7 GO:0004842 Not Cancer Driver No 60 0.0792602377807133 257 19 0.0250990752972258 0
SMURF2-201 SMURF2 Q9HAU4 E3 ubiquitin-protein ligase SMURF2 chr17 GO:0004842 Not Cancer Driver No 63 0.0842245989304812 244 19 0.0254010695187165 0
STUB1-201 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:0004842 Not Cancer Driver No 29 0.0957095709570957 113 11 0.0363036303630363 11
TNFAIP1-201 TNFAIP1 Q13829 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 chr17 GO:0004842 Not Cancer Driver No 24 0.0759493670886076 39 2 0.0063291139240506 0
TNFAIP3-206 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0004842 Census, Compendium Yes 69 0.0873417721518987 231 21 0.0265822784810126 1
TOPORS-201 TOPORS Q9NS56 E3 ubiquitin-protein ligase Topors chr9 GO:0004842 Not Cancer Driver No 62 0.0593301435406698 796 38 0.0363636363636363 0
TRAF2-201 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0004842 Not Cancer Driver No 51 0.1017964071856287 4 1 0.0019960079840319 0
TRAF3-202 TRAF3 Q13114 TNF receptor-associated factor 3 chr14 GO:0004842 Compendium Yes 49 0.0862676056338028 101 8 0.0140845070422535 1
TRAF6-202 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0004842 Not Cancer Driver No 51 0.0977011494252873 62 5 0.0095785440613026 0
TRAF7-201 TRAF7 Q6Q0C0 E3 ubiquitin-protein ligase TRAF7 chr16 GO:0004842 Census Yes 65 0.0970149253731343 121 13 0.0194029850746268 4
TRAIP-201 TRAIP Q9BWF2 E3 ubiquitin-protein ligase TRAIP chr3 GO:0004842 Not Cancer Driver No 42 0.0895522388059701 240 22 0.0469083155650319 1
TRIM11-201 TRIM11 Q96F44 E3 ubiquitin-protein ligase TRIM11 chr1 GO:0004842 Not Cancer Driver No 46 0.0982905982905982 132 16 0.0341880341880341 0
TRIM13-202 TRIM13 O60858 E3 ubiquitin-protein ligase TRIM13 chr13 GO:0004842 Not Cancer Driver No 41 0.1007371007371007 1 0 0.0 0
TRIM17-204 TRIM17 Q9Y577 E3 ubiquitin-protein ligase TRIM17 chr1 GO:0004842 Not Cancer Driver No 53 0.1111111111111111 129 16 0.0335429769392033 0
TRIM2-282 TRIM2 Q9C040 Tripartite motif-containing protein 2 chr4 GO:0004842 Not Cancer Driver No 60 0.0806451612903225 239 28 0.0376344086021505 1
TRIM21-201 TRIM21 P19474 E3 ubiquitin-protein ligase TRIM21 chr11 GO:0004842 Not Cancer Driver No 63 0.1326315789473684 49 8 0.0168421052631578 0
TRIM23-201 TRIM23 P36406 E3 ubiquitin-protein ligase TRIM23 chr5 GO:0004842 Not Cancer Driver No 65 0.1132404181184669 39 2 0.0034843205574912 0
TRIM25-201 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 GO:0004842 Not Cancer Driver No 45 0.0714285714285714 226 11 0.0174603174603174 0
TRIM27-202 TRIM27 P14373 Zinc finger protein RFP chr6 GO:0004842 Census Yes 46 0.0896686159844054 87 9 0.0175438596491228 0
TRIM28-201 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 GO:0004842 Not Cancer Driver No 67 0.0802395209580838 431 32 0.0383233532934131 0
TRIM32-203 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:0004842 Not Cancer Driver No 62 0.0949464012251148 87 9 0.0137825421133231 3
TRIM33-201 TRIM33 Q9UPN9 E3 ubiquitin-protein ligase TRIM33 chr1 GO:0004842 Census, Compendium Yes 71 0.0629991126885536 618 34 0.0301685891748003 0
TRIM36-201 TRIM36 Q9NQ86 E3 ubiquitin-protein ligase TRIM36 chr5 GO:0004842 Not Cancer Driver No 81 0.1112637362637362 89 15 0.0206043956043956 1
TRIM37-201 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 GO:0004842 Not Cancer Driver No 89 0.0923236514522821 493 42 0.0435684647302904 3
TRIM4-203 TRIM4 Q9C037 E3 ubiquitin-protein ligase TRIM4 chr7 GO:0004842 Not Cancer Driver No 27 0.054 40 2 0.004 0
TRIM47-201 TRIM47 Q96LD4 E3 ubiquitin-protein ligase TRIM47 chr17 GO:0004842 Not Cancer Driver No 35 0.054858934169279 202 8 0.012539184952978 0
TRIM5-202 TRIM5 Q9C035 Tripartite motif-containing protein 5 chr11 GO:0004842 Not Cancer Driver No 38 0.0770791075050709 78 7 0.0141987829614604 0
TRIM56-201 TRIM56 Q9BRZ2 E3 ubiquitin-protein ligase TRIM56 chr7 GO:0004842 Not Cancer Driver No 79 0.1046357615894039 221 31 0.0410596026490066 0
TRIM62-201 TRIM62 Q9BVG3 E3 ubiquitin-protein ligase TRIM62 chr1 GO:0004842 Not Cancer Driver No 47 0.0989473684210526 81 12 0.0252631578947368 0
TRIM68-201 TRIM68 Q6AZZ1 E3 ubiquitin-protein ligase TRIM68 chr11 GO:0004842 Not Cancer Driver No 56 0.1154639175257732 37 7 0.0144329896907216 0
TRIM69-201 TRIM69 Q86WT6 E3 ubiquitin-protein ligase TRIM69 chr15 GO:0004842 Not Cancer Driver No 51 0.102 62 13 0.026 0
TRIM71-201 TRIM71 Q2Q1W2 E3 ubiquitin-protein ligase TRIM71 chr3 GO:0004842 Not Cancer Driver No 86 0.0990783410138248 163 13 0.0149769585253456 2
TTC3-206 TTC3 P53804 E3 ubiquitin-protein ligase TTC3 chr21 GO:0004842 Not Cancer Driver No 167 0.0824691358024691 727 54 0.0266666666666666 0
UBA7-201 UBA7 P41226 Ubiquitin-like modifier-activating enzyme 7 chr3 GO:0004842 Not Cancer Driver No 70 0.0691699604743083 167 14 0.0138339920948616 0
UBE2A-202 UBE2A P49459 Ubiquitin-conjugating enzyme E2 A chrX GO:0004842 Compendium Yes 23 0.1513157894736842 67 11 0.0723684210526315 2
UBE2B-201 UBE2B P63146 Ubiquitin-conjugating enzyme E2 B chr5 GO:0004842 Not Cancer Driver No 9 0.0592105263157894 68 4 0.0263157894736842 0
UBE2C-204 UBE2C O00762 Ubiquitin-conjugating enzyme E2 C chr20 GO:0004842 Not Cancer Driver No 13 0.0726256983240223 40 0 0.0 0
UBE2D1-201 UBE2D1 P51668 Ubiquitin-conjugating enzyme E2 D1 chr10 GO:0004842 Not Cancer Driver No 9 0.0612244897959183 14 0 0.0 0
UBE2D2-201 UBE2D2 P62837 Ubiquitin-conjugating enzyme E2 D2 chr5 GO:0004842 Compendium Yes 14 0.0952380952380952 13 1 0.0068027210884353 0
UBE2D3-210 UBE2D3 P61077 Ubiquitin-conjugating enzyme E2 D3 chr4 GO:0004842 Not Cancer Driver No 15 0.1020408163265306 13 3 0.0204081632653061 0
UBE2D4-201 UBE2D4 Q9Y2X8 Ubiquitin-conjugating enzyme E2 D4 chr7 GO:0004842 Not Cancer Driver No 7 0.0476190476190476 21 1 0.0068027210884353 0
UBE2E1-201 UBE2E1 P51965 Ubiquitin-conjugating enzyme E2 E1 chr3 GO:0004842 Not Cancer Driver No 11 0.0569948186528497 79 4 0.0207253886010362 0
UBE2E2-202 UBE2E2 Q96LR5 Ubiquitin-conjugating enzyme E2 E2 chr3 GO:0004842 Not Cancer Driver No 23 0.1144278606965174 90 11 0.0547263681592039 0
UBE2E3-202 UBE2E3 Q969T4 Ubiquitin-conjugating enzyme E2 E3 chr2 GO:0004842 Not Cancer Driver No 22 0.1062801932367149 98 10 0.0483091787439613 0
UBE2G1-201 UBE2G1 P62253 Ubiquitin-conjugating enzyme E2 G1 chr17 GO:0004842 Not Cancer Driver No 4 0.0235294117647058 39 1 0.0058823529411764 0
UBE2G2-202 UBE2G2 P60604 Ubiquitin-conjugating enzyme E2 G2 chr21 GO:0004842 Not Cancer Driver No 18 0.109090909090909 22 4 0.0242424242424242 0
UBE2H-201 UBE2H P62256 Ubiquitin-conjugating enzyme E2 H chr7 GO:0004842 Not Cancer Driver No 14 0.0765027322404371 55 7 0.0382513661202185 0
UBE2K-201 UBE2K P61086 Ubiquitin-conjugating enzyme E2 K chr4 GO:0004842 Not Cancer Driver No 18 0.09 33 2 0.01 0
UBE2L3-201 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 GO:0004842 Not Cancer Driver No 13 0.0844155844155844 32 3 0.0194805194805194 0
UBE2L6-201 UBE2L6 O14933 Ubiquitin/ISG15-conjugating enzyme E2 L6 chr11 GO:0004842 Not Cancer Driver No 13 0.0849673202614379 7 1 0.0065359477124183 0
UBE2M-201 UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 GO:0004842 Not Cancer Driver No 25 0.1366120218579235 32 4 0.0218579234972677 0
UBE2N-201 UBE2N P61088 Ubiquitin-conjugating enzyme E2 N chr12 GO:0004842 Not Cancer Driver No 19 0.125 24 1 0.006578947368421 0
UBE2O-201 UBE2O Q9C0C9 (E3-independent) E2 ubiquitin-conjugating enzyme chr17 GO:0004842 Not Cancer Driver No 94 0.0727554179566563 717 54 0.0417956656346749 0
UBE2Q2-201 UBE2Q2 Q8WVN8 Ubiquitin-conjugating enzyme E2 Q2 chr15 GO:0004842 Not Cancer Driver No 28 0.0746666666666666 122 8 0.0213333333333333 0
UBE2R2-201 UBE2R2 Q712K3 Ubiquitin-conjugating enzyme E2 R2 chr9 GO:0004842 Not Cancer Driver No 18 0.0756302521008403 105 8 0.0336134453781512 0
UBE2S-201 UBE2S Q16763 Ubiquitin-conjugating enzyme E2 S chr19 GO:0004842 Not Cancer Driver No 15 0.0675675675675675 102 5 0.0225225225225225 0
UBE2T-205 UBE2T Q9NPD8 Ubiquitin-conjugating enzyme E2 T chr1 GO:0004842 Not Cancer Driver No 11 0.0558375634517766 97 8 0.0406091370558375 1
UBE2W-207 UBE2W Q96B02 Ubiquitin-conjugating enzyme E2 W chr8 GO:0004842 Not Cancer Driver No 12 0.0794701986754966 26 3 0.0198675496688741 0
UBE3A-228 UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0004842 Not Cancer Driver No 90 0.1028571428571428 136 16 0.0182857142857142 0
UBR3-201 UBR3 Q6ZT12 E3 ubiquitin-protein ligase UBR3 chr2 GO:0004842 Not Cancer Driver No 110 0.0582627118644067 339 23 0.0121822033898305 0
UBR4-204 UBR4 Q5T4S7 E3 ubiquitin-protein ligase UBR4 chr1 GO:0004842 Not Cancer Driver No 433 0.083542349990353 1069 97 0.0187150299054601 0
UHRF1-208 UHRF1 Q96T88 E3 ubiquitin-protein ligase UHRF1 chr19 GO:0004842 Not Cancer Driver No 0 0.0 353 0 0.0 0
UHRF2-201 UHRF2 Q96PU4 E3 ubiquitin-protein ligase UHRF2 chr9 GO:0004842 Not Cancer Driver No 67 0.0835411471321695 254 16 0.0199501246882793 0
VHL-201 VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 GO:0004842 Census, Compendium Yes 85 0.3990610328638497 117 15 0.0704225352112676 84
WDSUB1-202 WDSUB1 Q8N9V3 WD repeat, SAM and U-box domain-containing protein 1 chr2 GO:0004842 Not Cancer Driver No 32 0.0672268907563025 18 1 0.0021008403361344 0
WWP1-202 WWP1 Q9H0M0 NEDD4-like E3 ubiquitin-protein ligase WWP1 chr8 GO:0004842 Not Cancer Driver No 104 0.1127982646420824 432 55 0.0596529284164859 0
WWP2-202 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 GO:0004842 Not Cancer Driver No 87 0.1 423 46 0.0528735632183908 0
XIAP-202 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX GO:0004842 Not Cancer Driver No 61 0.1227364185110664 55 2 0.0040241448692152 0
ZFP91-201 ZFP91 Q96JP5 E3 ubiquitin-protein ligase ZFP91 chr11 GO:0004842 Not Cancer Driver No 74 0.1298245614035087 384 52 0.0912280701754386 0
ZFP91-CNTF-201 ZFP91 Q96JP5 E3 ubiquitin-protein ligase ZFP91 chr11 GO:0004842 Not Cancer Driver No 70 0.1323251417769376 352 48 0.0907372400756143 0
ZNF738-206 ZNF738 Q8NE65 Zinc finger protein 738 chr19 GO:0004842 Not Cancer Driver No 12 0.032 16 0 0.0 0
ZNRF1-202 ZNRF1 Q8ND25 E3 ubiquitin-protein ligase ZNRF1 chr16 GO:0004842 Not Cancer Driver No 15 0.066079295154185 115 2 0.0088105726872246 0
ZNRF3-203 ZNRF3 Q9ULT6 E3 ubiquitin-protein ligase ZNRF3 chr22 GO:0004842 Census, Compendium Yes 74 0.079059829059829 510 39 0.0416666666666666 0