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Total number of protein in "GO:0005085" GO term:  228

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABR-202 ABR Q12979 Active breakpoint cluster region-related protein chr17 GO:0005085 Not Cancer Driver No 87 0.1012805587892898 185 25 0.029103608847497 0
AKAP13-203 AKAP13 Q12802 A-kinase anchor protein 13 chr15 GO:0005085 Not Cancer Driver No 260 0.0924280127977248 2107 187 0.066477070742979 0
ALS2-201 ALS2 Q96Q42 Alsin chr2 GO:0005085 Not Cancer Driver No 133 0.08026554013277 354 24 0.0144840072420036 0
ALS2CL-201 ALS2CL Q60I27 ALS2 C-terminal-like protein chr3 GO:0005085 Not Cancer Driver No 85 0.0891920251836306 134 6 0.0062959076600209 0
ANKRD27-201 ANKRD27 Q96NW4 Ankyrin repeat domain-containing protein 27 chr19 GO:0005085 Not Cancer Driver No 102 0.0971428571428571 239 27 0.0257142857142857 0
ARF4-201 ARF4 P18085 ADP-ribosylation factor 4 chr3 GO:0005085 Not Cancer Driver No 7 0.0388888888888888 0 0 0.0 0
ARFGEF1-201 ARFGEF1 Q9Y6D6 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 chr8 GO:0005085 Not Cancer Driver No 172 0.0930232558139534 457 47 0.0254191454840454 1
ARFGEF2-201 ARFGEF2 Q9Y6D5 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 chr20 GO:0005085 Not Cancer Driver No 188 0.1053221288515406 358 49 0.0274509803921568 0
ARFGEF3-201 ARFGEF3 Q5TH69 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 chr6 GO:0005085 Not Cancer Driver No 214 0.0983004134129536 589 52 0.0238860817638952 0
ARHGEF1-203 ARHGEF1 Q92888 Rho guanine nucleotide exchange factor 1 chr19 GO:0005085 Not Cancer Driver No 100 0.1096491228070175 457 54 0.0592105263157894 0
ARHGEF10-204 ARHGEF10 O15013 Rho guanine nucleotide exchange factor 10 chr8 GO:0005085 Census, Compendium Yes 114 0.08327246165084 587 50 0.0365230094959824 1
ARHGEF10L-202 ARHGEF10L Q9HCE6 Rho guanine nucleotide exchange factor 10-like protein chr1 GO:0005085 Census, Compendium Yes 114 0.0891321344800625 436 30 0.0234558248631743 0
ARHGEF11-201 ARHGEF11 O15085 Rho guanine nucleotide exchange factor 11 chr1 GO:0005085 Not Cancer Driver No 170 0.1116951379763469 1038 113 0.0742444152431011 0
ARHGEF12-202 ARHGEF12 Q9NZN5 Rho guanine nucleotide exchange factor 12 chr11 GO:0005085 Census, Compendium Yes 141 0.091321243523316 974 103 0.0667098445595855 0
ARHGEF15-201 ARHGEF15 O94989 Rho guanine nucleotide exchange factor 15 chr17 GO:0005085 Not Cancer Driver No 119 0.1414982164090368 538 81 0.0963139120095124 0
ARHGEF16-203 ARHGEF16 Q5VV41 Rho guanine nucleotide exchange factor 16 chr1 GO:0005085 Not Cancer Driver No 55 0.077574047954866 299 10 0.0141043723554301 0
ARHGEF17-201 ARHGEF17 Q96PE2 Rho guanine nucleotide exchange factor 17 chr11 GO:0005085 Not Cancer Driver No 190 0.092098885118759 1412 142 0.0688317983519146 0
ARHGEF18-206 ARHGEF18 Q6ZSZ5 Rho guanine nucleotide exchange factor 18 chr19 GO:0005085 Not Cancer Driver No 102 0.0749448934606906 945 57 0.0418809698750918 1
ARHGEF19-201 ARHGEF19 Q8IW93 Rho guanine nucleotide exchange factor 19 chr1 GO:0005085 Not Cancer Driver No 64 0.0798004987531172 366 30 0.0374064837905236 0
ARHGEF2-203 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 GO:0005085 Not Cancer Driver No 121 0.1227180527383367 450 64 0.0649087221095334 0
ARHGEF25-201 ARHGEF25 Q86VW2 Rho guanine nucleotide exchange factor 25 chr12 GO:0005085 Not Cancer Driver No 54 0.093103448275862 243 26 0.0448275862068965 0
ARHGEF26-202 ARHGEF26 Q96DR7 Rho guanine nucleotide exchange factor 26 chr3 GO:0005085 Not Cancer Driver No 100 0.1148105625717566 481 54 0.0619977037887485 0
ARHGEF28-212 ARHGEF28 Q8N1W1 Rho guanine nucleotide exchange factor 28 chr5 GO:0005085 Not Cancer Driver No 124 0.0727272727272727 772 63 0.0369501466275659 0
ARHGEF3-201 ARHGEF3 Q9NR81 Rho guanine nucleotide exchange factor 3 chr3 GO:0005085 Not Cancer Driver No 45 0.085551330798479 157 10 0.0190114068441064 0
ARHGEF33-202 ARHGEF33 A8MVX0 Rho guanine nucleotide exchange factor 33 chr2 GO:0005085 Not Cancer Driver No 25 0.028735632183908 618 15 0.0172413793103448 0
ARHGEF37-201 ARHGEF37 A1IGU5 Rho guanine nucleotide exchange factor 37 chr5 GO:0005085 Not Cancer Driver No 58 0.0859259259259259 167 21 0.0311111111111111 0
ARHGEF38-202 ARHGEF38 Q9NXL2 Rho guanine nucleotide exchange factor 38 chr4 GO:0005085 Not Cancer Driver No 18 0.0231660231660231 156 5 0.0064350064350064 0
ARHGEF39-201 ARHGEF39 Q8N4T4 Rho guanine nucleotide exchange factor 39 chr9 GO:0005085 Not Cancer Driver No 28 0.0835820895522388 56 5 0.0149253731343283 0
ARHGEF4-201 ARHGEF4 Q9NR80 Rho guanine nucleotide exchange factor 4 chr2 GO:0005085 Not Cancer Driver No 85 0.1231884057971014 291 50 0.072463768115942 0
ARHGEF40-201 ARHGEF40 Q8TER5 Rho guanine nucleotide exchange factor 40 chr14 GO:0005085 Not Cancer Driver No 127 0.0836076366030283 784 55 0.0362080315997366 0
ARHGEF5-201 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:0005085 Not Cancer Driver No 122 0.0763932373199749 1141 89 0.0557294927989981 0
ARHGEF6-201 ARHGEF6 Q15052 Rho guanine nucleotide exchange factor 6 chrX GO:0005085 Not Cancer Driver No 106 0.1365979381443298 224 28 0.0360824742268041 0
ARHGEF7-206 ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 chr13 GO:0005085 Not Cancer Driver No 67 0.0834371108343711 302 30 0.037359900373599 0
ARHGEF9-201 ARHGEF9 O43307 Rho guanine nucleotide exchange factor 9 chrX GO:0005085 Not Cancer Driver No 76 0.1472868217054263 88 3 0.005813953488372 3
BCAR3-201 BCAR3 O75815 Breast cancer anti-estrogen resistance protein 3 chr1 GO:0005085 Not Cancer Driver No 74 0.0896969696969696 397 34 0.0412121212121212 0
BCR-201 BCR P11274 Breakpoint cluster region protein chr22 GO:0005085 Census, Compendium Yes 112 0.088119590873328 607 57 0.044846577498033 0
C9orf72-203 C9orf72 Q96LT7 Guanine nucleotide exchange factor C9orf72 chr9 GO:0005085 Not Cancer Driver No 41 0.0852390852390852 11 0 0.0 0
CCDC88A-207 CCDC88A Q3V6T2 Girdin chr2 GO:0005085 Not Cancer Driver No 145 0.0774986638161411 1481 114 0.0609299839657936 0
CCDC88C-203 CCDC88C Q9P219 Protein Daple chr14 GO:0005085 Not Cancer Driver No 183 0.0902366863905325 1615 147 0.0724852071005917 1
CCZ1-201 CCZ1 P86791 Vacuolar fusion protein CCZ1 homolog chr7 GO:0005085 Not Cancer Driver No 24 0.0497925311203319 43 0 0.0 0
CCZ1B-201 CCZ1 P86791 Vacuolar fusion protein CCZ1 homolog chr7 GO:0005085 Not Cancer Driver No 18 0.0373443983402489 43 2 0.0041493775933609 0
CYTH1-201 CYTH1 Q15438 Cytohesin-1 chr17 GO:0005085 Not Cancer Driver No 41 0.1030150753768844 93 7 0.0175879396984924 0
CYTH2-213 CYTH2 Q99418 Cytohesin-2 chr19 GO:0005085 Not Cancer Driver No 44 0.11 94 10 0.025 0
CYTH3-201 CYTH3 O43739 Cytohesin-3 chr7 GO:0005085 Not Cancer Driver No 43 0.1077694235588972 94 9 0.0225563909774436 0
CYTH4-201 CYTH4 Q9UIA0 Cytohesin-4 chr22 GO:0005085 Not Cancer Driver No 52 0.1319796954314721 54 9 0.0228426395939086 0
DEF6-201 DEF6 Q9H4E7 Differentially expressed in FDCP 6 homolog chr6 GO:0005085 Not Cancer Driver No 42 0.0665610142630744 337 4 0.0063391442155309 2
DENND10-201 DENND10 Q8TCE6 DENN domain-containing protein 10 chr10 GO:0005085 Not Cancer Driver No 23 0.0644257703081232 13 1 0.0028011204481792 0
DENND11-202 DENND11 A4D1U4 DENN domain-containing protein 11 chr7 GO:0005085 Not Cancer Driver No 44 0.0967032967032967 82 0 0.0 0
DENND1A-203 DENND1A Q8TEH3 DENN domain-containing protein 1A chr9 GO:0005085 Not Cancer Driver No 98 0.0971258671952428 591 63 0.062438057482656 0
DENND1B-211 DENND1B Q6P3S1 DENN domain-containing protein 1B chr1 GO:0005085 Not Cancer Driver No 29 0.0374193548387096 301 0 0.0 0
DENND1C-201 DENND1C Q8IV53 DENN domain-containing protein 1C chr19 GO:0005085 Not Cancer Driver No 72 0.0898876404494382 372 41 0.0511860174781523 0
DENND2A-209 DENND2A Q9ULE3 DENN domain-containing protein 2A chr7 GO:0005085 Not Cancer Driver No 149 0.1476709613478691 541 85 0.0842418235877106 0
DENND2B-201 DENND2B P78524 DENN domain-containing protein 2B chr11 GO:0005085 Not Cancer Driver No 104 0.0914687774846086 672 69 0.0606860158311345 0
DENND2C-201 DENND2C Q68D51 DENN domain-containing protein 2C chr1 GO:0005085 Not Cancer Driver No 122 0.1314655172413793 353 44 0.0474137931034482 0
DENND2D-201 DENND2D Q9H6A0 DENN domain-containing protein 2D chr1 GO:0005085 Not Cancer Driver No 42 0.0891719745222929 54 2 0.0042462845010615 0
DENND3-201 DENND3 A2RUS2 DENN domain-containing protein 3 chr8 GO:0005085 Not Cancer Driver No 138 0.1151919866444073 121 17 0.0141903171953255 0
DENND4A-201 DENND4A Q7Z401 C-myc promoter-binding protein chr15 GO:0005085 Not Cancer Driver No 125 0.0670960815888352 570 41 0.0220075147611379 0
DENND4B-201 DENND4B O75064 DENN domain-containing protein 4B chr1 GO:0005085 Not Cancer Driver No 152 0.1016042780748663 500 54 0.0360962566844919 0
DENND4C-209 DENND4C Q5VZ89 DENN domain-containing protein 4C chr9 GO:0005085 Not Cancer Driver No 121 0.0633839706652697 709 40 0.0209533787323205 0
DENND5A-201 DENND5A Q6IQ26 DENN domain-containing protein 5A chr11 GO:0005085 Not Cancer Driver No 105 0.0815850815850815 232 17 0.0132090132090132 0
DENND5B-202 DENND5B Q6ZUT9 DENN domain-containing protein 5B chr12 GO:0005085 Not Cancer Driver No 124 0.097331240188383 194 19 0.0149136577708006 0
DENND6A-201 DENND6A Q8IWF6 Protein DENND6A chr3 GO:0005085 Not Cancer Driver No 39 0.0641447368421052 70 1 0.0016447368421052 0
DENND6B-201 DENND6B Q8NEG7 Protein DENND6B chr22 GO:0005085 Not Cancer Driver No 36 0.0615384615384615 54 3 0.0051282051282051 0
DIS3-201 DIS3 Q9Y2L1 Exosome complex exonuclease RRP44 chr13 GO:0005085 Compendium Yes 72 0.0751565762004175 236 18 0.0187891440501043 0
DNMBP-201 DNMBP Q6XZF7 Dynamin-binding protein chr10 GO:0005085 Not Cancer Driver No 140 0.0887761572606214 759 65 0.0412175015852885 0
DOCK1-201 DOCK1 Q14185 Dedicator of cytokinesis protein 1 chr10 GO:0005085 Not Cancer Driver No 168 0.0900804289544235 356 37 0.0198391420911528 0
DOCK10-201 DOCK10 Q96BY6 Dedicator of cytokinesis protein 10 chr2 GO:0005085 Not Cancer Driver No 270 0.1235132662397072 411 40 0.0182982616651418 0
DOCK11-201 DOCK11 Q5JSL3 Dedicator of cytokinesis protein 11 chrX GO:0005085 Not Cancer Driver No 222 0.1070911722141823 240 22 0.0106126386878919 0
DOCK2-210 DOCK2 Q92608 Dedicator of cytokinesis protein 2 chr5 GO:0005085 Not Cancer Driver No 382 0.2087431693989071 267 71 0.0387978142076502 2
DOCK3-201 DOCK3 Q8IZD9 Dedicator of cytokinesis protein 3 chr3 GO:0005085 Not Cancer Driver No 269 0.1325123152709359 458 51 0.0251231527093596 0
DOCK4-206 DOCK4 Q8N1I0 Dedicator of cytokinesis protein 4 chr7 GO:0005085 Not Cancer Driver No 258 0.1312309257375381 398 67 0.0340793489318413 0
DOCK5-201 DOCK5 Q9H7D0 Dedicator of cytokinesis protein 5 chr8 GO:0005085 Not Cancer Driver No 190 0.1016042780748663 330 31 0.0165775401069518 0
DOCK6-201 DOCK6 Q96HP0 Dedicator of cytokinesis protein 6 chr19 GO:0005085 Not Cancer Driver No 151 0.0737664875427454 499 40 0.0195407914020517 0
DOCK7-219 DOCK7 Q96N67 Dedicator of cytokinesis protein 7 chr1 GO:0005085 Not Cancer Driver No 183 0.0855140186915887 455 33 0.0154205607476635 0
DOCK8-204 DOCK8 Q8NF50 Dedicator of cytokinesis protein 8 chr9 GO:0005085 Not Cancer Driver No 198 0.0943306336350643 315 40 0.0190566936636493 1
DOCK9-217 DOCK9 Q9BZ29 Dedicator of cytokinesis protein 9 chr13 GO:0005085 Not Cancer Driver No 168 0.0811986466892218 183 11 0.0053165780570323 0
ECT2-204 ECT2 Q9H8V3 Protein ECT2 chr3 GO:0005085 Not Cancer Driver No 67 0.0733041575492341 284 20 0.0218818380743982 0
ECT2L-204 ECT2L Q008S8 Epithelial cell-transforming sequence 2 oncogene-like chr6 GO:0005085 Census Yes 91 0.1006637168141593 32 6 0.0066371681415929 0
EEF1B2-203 EEF1B2 P24534 Elongation factor 1-beta chr2 GO:0005085 Not Cancer Driver No 22 0.0977777777777777 71 7 0.0311111111111111 0
EEF1D-246 EEF1D P29692 Elongation factor 1-delta chr8 GO:0005085 Not Cancer Driver No 30 0.1067615658362989 153 20 0.0711743772241993 0
EGF-201 EGF P01133 Pro-epidermal growth factor chr4 GO:0005085 Not Cancer Driver No 149 0.1234465617232808 193 22 0.0182270091135045 1
EIF2B1-201 EIF2B1 Q14232 Translation initiation factor eIF-2B subunit alpha chr12 GO:0005085 Not Cancer Driver No 32 0.1049180327868852 0 0 0.0 2
EIF2B2-201 EIF2B2 P49770 Translation initiation factor eIF-2B subunit beta chr14 GO:0005085 Not Cancer Driver No 34 0.0968660968660968 83 9 0.0256410256410256 9
EIF2B3-201 EIF2B3 Q9NR50 Translation initiation factor eIF-2B subunit gamma chr1 GO:0005085 Not Cancer Driver No 38 0.084070796460177 28 7 0.0154867256637168 5
EIF2B4-201 EIF2B4 Q9UI10 Translation initiation factor eIF-2B subunit delta chr2 GO:0005085 Not Cancer Driver No 49 0.0936902485659655 212 26 0.0497131931166348 7
EIF2B5-226 EIF2B5 Q13144 Translation initiation factor eIF-2B subunit epsilon chr3 GO:0005085 Not Cancer Driver No 49 0.0679611650485436 179 9 0.0124826629680998 21
ELMO1-201 ELMO1 Q92556 Engulfment and cell motility protein 1 chr7 GO:0005085 Not Cancer Driver No 158 0.2173314993122421 98 21 0.0288858321870701 0
ENST00000514667 RAPGEF6 Q8TEU7 Rap guanine nucleotide exchange factor 6 chr5 GO:0005085 Not Cancer Driver No 148 0.0896426408237431 769 68 0.0411871592973955 0
EPS8L1-201 EPS8L1 Q8TE68 Epidermal growth factor receptor kinase substrate 8-like protein 1 chr19 GO:0005085 Not Cancer Driver No 69 0.0954356846473029 521 55 0.0760719225449515 0
EPS8L2-201 EPS8L2 Q9H6S3 Epidermal growth factor receptor kinase substrate 8-like protein 2 chr11 GO:0005085 Not Cancer Driver No 54 0.0755244755244755 376 25 0.0349650349650349 0
EPS8L3-202 EPS8L3 Q8TE67 Epidermal growth factor receptor kinase substrate 8-like protein 3 chr1 GO:0005085 Not Cancer Driver No 81 0.1365935919055649 341 42 0.0708263069139966 0
FARP1-201 FARP1 Q9Y4F1 FERM, ARHGEF and pleckstrin domain-containing protein 1 chr13 GO:0005085 Not Cancer Driver No 105 0.1004784688995215 314 44 0.0421052631578947 0
FARP2-201 FARP2 O94887 FERM, ARHGEF and pleckstrin domain-containing protein 2 chr2 GO:0005085 Not Cancer Driver No 100 0.0948766603415559 252 29 0.0275142314990512 0
FBXO8-201 FBXO8 Q9NRD0 F-box only protein 8 chr4 GO:0005085 Not Cancer Driver No 26 0.0815047021943573 25 0 0.0 0
FGD1-201 FGD1 P98174 FYVE, RhoGEF and PH domain-containing protein 1 chrX GO:0005085 Not Cancer Driver No 105 0.109261186264308 521 60 0.0624349635796045 5
FGD2-201 FGD2 Q7Z6J4 FYVE, RhoGEF and PH domain-containing protein 2 chr6 GO:0005085 Not Cancer Driver No 84 0.1282442748091603 160 16 0.0244274809160305 0
FGD3-202 FGD3 Q5JSP0 FYVE, RhoGEF and PH domain-containing protein 3 chr9 GO:0005085 Not Cancer Driver No 90 0.1241379310344827 407 51 0.0703448275862069 0
FGD4-202 FGD4 Q96M96 FYVE, RhoGEF and PH domain-containing protein 4 chr12 GO:0005085 Not Cancer Driver No 61 0.0796344647519582 291 24 0.031331592689295 1
FGD5-201 FGD5 Q6ZNL6 FYVE, RhoGEF and PH domain-containing protein 5 chr3 GO:0005085 Compendium Yes 197 0.1347469220246238 917 134 0.0916552667578659 0
FGD6-201 FGD6 Q6ZV73 FYVE, RhoGEF and PH domain-containing protein 6 chr12 GO:0005085 Not Cancer Driver No 141 0.0986013986013986 809 79 0.0552447552447552 0
FRMD7-201 FRMD7 Q6ZUT3 FERM domain-containing protein 7 chrX GO:0005085 Not Cancer Driver No 118 0.165266106442577 260 48 0.0672268907563025 20
GAPVD1-205 GAPVD1 Q14C86 GTPase-activating protein and VPS9 domain-containing protein 1 chr9 GO:0005085 Not Cancer Driver No 136 0.0920162381596752 705 73 0.0493910690121786 0
GBF1-223 GBF1 Q92538 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 chr10 GO:0005085 Not Cancer Driver No 161 0.0866057019903173 670 62 0.0333512641204948 0
GCGR-201 GCGR P47871 Glucagon receptor chr17 GO:0005085 Not Cancer Driver No 12 0.0251572327044025 56 2 0.0041928721174004 4
GDPGP1-201 GDPGP1 Q6ZNW5 GDP-D-glucose phosphorylase 1 chr15 GO:0005085 Not Cancer Driver No 32 0.0831168831168831 85 8 0.0207792207792207 0
GNA13-201 GNA13 Q14344 Guanine nucleotide-binding protein subunit alpha-13 chr17 GO:0005085 Compendium Yes 45 0.1193633952254641 32 4 0.0106100795755968 0
GRIPAP1-201 GRIPAP1 Q4V328 GRIP1-associated protein 1 chrX GO:0005085 Not Cancer Driver No 78 0.0927467300832342 726 69 0.0820451843043995 0
HERC1-201 HERC1 Q15751 Probable E3 ubiquitin-protein ligase HERC1 chr15 GO:0005085 Not Cancer Driver No 350 0.0720016457519029 1353 102 0.0209833367619831 1
HERC2-201 HERC2 O95714 E3 ubiquitin-protein ligase HERC2 chr15 GO:0005085 Compendium Yes 517 0.1069507654116673 971 113 0.0233760860570955 1
HPS1-203 HPS1 Q92902 BLOC-3 complex member HPS1 chr10 GO:0005085 Not Cancer Driver No 56 0.08 154 13 0.0185714285714285 0
HPS4-202 HPS4 Q9NQG7 BLOC-3 complex member HPS4 chr22 GO:0005085 Not Cancer Driver No 70 0.0988700564971751 345 38 0.0536723163841807 0
IQSEC1-201 IQSEC1 Q6DN90 IQ motif and SEC7 domain-containing protein 1 chr3 GO:0005085 Not Cancer Driver No 109 0.1131879543094496 609 76 0.0789200415368639 2
IQSEC2-218 IQSEC2 Q5JU85 IQ motif and SEC7 domain-containing protein 2 chrX GO:0005085 Not Cancer Driver No 119 0.0799731182795698 1140 69 0.0463709677419354 5
IQSEC3-203 IQSEC3 Q9UPP2 IQ motif and SEC7 domain-containing protein 3 chr12 GO:0005085 Not Cancer Driver No 133 0.1125211505922165 683 66 0.0558375634517766 0
ITSN1-206 ITSN1 Q15811 Intersectin-1 chr21 GO:0005085 Not Cancer Driver No 109 0.0633352701917489 798 50 0.0290528762347472 0
ITSN2-201 ITSN2 Q9NZM3 Intersectin-2 chr2 GO:0005085 Not Cancer Driver No 92 0.0542133176193282 681 33 0.0194460813199764 0
KALRN-204 KALRN O60229 Kalirin chr3 GO:0005085 Not Cancer Driver No 371 0.124246483590087 739 106 0.0354989953114534 0
KIAA1755-201 KIAA1755 Q5JYT7 Uncharacterized protein KIAA1755 chr20 GO:0005085 Not Cancer Driver No 174 0.145 579 91 0.0758333333333333 0
KNDC1-201 KNDC1 Q76NI1 Kinase non-catalytic C-lobe domain-containing protein 1 chr10 GO:0005085 Not Cancer Driver No 209 0.1194968553459119 813 92 0.0526014865637507 0
LAMTOR1-201 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 GO:0005085 Not Cancer Driver No 10 0.062111801242236 96 6 0.0372670807453416 0
LAMTOR2-203 LAMTOR2 Q9Y2Q5 Ragulator complex protein LAMTOR2 chr1 GO:0005085 Not Cancer Driver No 9 0.072 0 0 0.0 0
LAMTOR3-202 LAMTOR3 Q9UHA4 Ragulator complex protein LAMTOR3 chr4 GO:0005085 Not Cancer Driver No 7 0.0564516129032258 0 0 0.0 0
LAMTOR4-201 LAMTOR4 Q0VGL1 Ragulator complex protein LAMTOR4 chr7 GO:0005085 Not Cancer Driver No 4 0.0404040404040404 4 0 0.0 0
LAMTOR5-206 LAMTOR5 O43504 Ragulator complex protein LAMTOR5 chr1 GO:0005085 Not Cancer Driver No 8 0.0879120879120879 17 0 0.0 0
MADD-201 MADD Q8WXG6 MAP kinase-activating death domain protein chr11 GO:0005085 Not Cancer Driver No 164 0.0995749848208864 726 65 0.0394656952034001 4
MCF2-203 MCF2 P10911 Proto-oncogene DBL chrX GO:0005085 Not Cancer Driver No 143 0.1545945945945946 124 19 0.0205405405405405 0
MCF2L-204 MCF2L O15068 Guanine nucleotide exchange factor DBS chr13 GO:0005085 Not Cancer Driver No 136 0.119613016710642 411 47 0.0413368513632365 0
MCF2L2-201 MCF2L2 Q86YR7 Probable guanine nucleotide exchange factor MCF2L2 chr3 GO:0005085 Not Cancer Driver No 155 0.1391382405745062 309 46 0.0412926391382405 0
MYCBP2-207 MYCBP2 O75592 E3 ubiquitin-protein ligase MYCBP2 chr13 GO:0005085 Not Cancer Driver No 411 0.0878580589995724 1402 114 0.0243693886276186 0
NET1-201 NET1 Q7Z628 Neuroepithelial cell-transforming gene 1 protein chr10 GO:0005085 Not Cancer Driver No 48 0.0805369127516778 297 32 0.0536912751677852 0
NGEF-201 NGEF Q8N5V2 Ephexin-1 chr2 GO:0005085 Not Cancer Driver No 92 0.1295774647887324 298 24 0.0338028169014084 0
NUCB1-201 NUCB1 Q02818 Nucleobindin-1 chr19 GO:0005085 Not Cancer Driver No 45 0.0976138828633405 352 34 0.0737527114967462 0
NUCB2-207 NUCB2 P80303 Nucleobindin-2 chr11 GO:0005085 Not Cancer Driver No 35 0.0833333333333333 266 31 0.0738095238095238 0
OBSCN-204 OBSCN Q5VST9 Obscurin chr1 GO:0005085 Not Cancer Driver No 914 0.1147088353413654 2651 286 0.0358935742971887 0
P2RY12-201 P2RY12 Q9H244 P2Y purinoceptor 12 chr3 GO:0005085 Not Cancer Driver No 38 0.1111111111111111 21 1 0.0029239766081871 3
PCP2-201 PCP2 Q8IVA1 Purkinje cell protein 2 homolog chr19 GO:0005085 Not Cancer Driver No 9 0.0661764705882353 136 9 0.0661764705882353 0
PLCD4-206 PLCD4 Q9BRC7 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 chr2 GO:0005085 Not Cancer Driver No 57 0.0748031496062992 90 5 0.0065616797900262 0
PLCE1-202 PLCE1 Q9P212 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 chr10 GO:0005085 Not Cancer Driver No 267 0.1159860990443093 785 79 0.0343179843614248 1
PLCG1-202 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 GO:0005085 Census, Compendium Yes 129 0.1 187 15 0.0116279069767441 0
PLEKHG1-209 PLEKHG1 Q9ULL1 Pleckstrin homology domain-containing family G member 1 chr6 GO:0005085 Not Cancer Driver No 134 0.0967509025270758 893 94 0.067870036101083 0
PLEKHG2-203 PLEKHG2 Q9H7P9 Pleckstrin homology domain-containing family G member 2 chr19 GO:0005085 Not Cancer Driver No 126 0.0909090909090909 1060 108 0.0779220779220779 1
PLEKHG3-201 PLEKHG3 A1L390 Pleckstrin homology domain-containing family G member 3 chr14 GO:0005085 Not Cancer Driver No 115 0.0943396226415094 887 88 0.0721903199343724 0
PLEKHG4-202 PLEKHG4 Q58EX7 Puratrophin-1 chr16 GO:0005085 Not Cancer Driver No 104 0.0873215785054576 296 26 0.0218303946263644 0
PLEKHG4B-201 PLEKHG4B Q96PX9 Pleckstrin homology domain-containing family G member 4B chr5 GO:0005085 Not Cancer Driver No 174 0.1369000786782061 712 80 0.06294256490952 0
PLEKHG5-203 PLEKHG5 O94827 Pleckstrin homology domain-containing family G member 5 chr1 GO:0005085 Not Cancer Driver No 81 0.0805168986083499 542 47 0.0467196819085487 3
PLEKHG6-210 PLEKHG6 Q3KR16 Pleckstrin homology domain-containing family G member 6 chr12 GO:0005085 Not Cancer Driver No 83 0.1050632911392405 471 53 0.0670886075949367 0
PLEKHG7-201 PLEKHG7 Q6ZR37 Pleckstrin homology domain-containing family G member 7 chr12 GO:0005085 Not Cancer Driver No 60 0.0868306801736613 174 22 0.0318379160636758 0
PREB-201 PREB Q9HCU5 Prolactin regulatory element-binding protein chr2 GO:0005085 Not Cancer Driver No 36 0.0863309352517985 91 7 0.0167865707434052 0
PREX1-201 PREX1 Q8TCU6 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein chr20 GO:0005085 Not Cancer Driver No 232 0.1398432790837854 310 48 0.0289330922242314 0
PREX2-201 PREX2 Q70Z35 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein chr8 GO:0005085 Census, Compendium Yes 404 0.2515566625155666 235 56 0.0348692403486924 0
PSD-201 PSD A5PKW4 PH and SEC7 domain-containing protein 1 chr10 GO:0005085 Not Cancer Driver No 149 0.1455078125 716 119 0.1162109375 0
PSD2-201 PSD2 Q9BQI7 PH and SEC7 domain-containing protein 2 chr5 GO:0005085 Not Cancer Driver No 107 0.1387808041504539 402 61 0.0791180285343709 0
PSD3-202 PSD3 Q9NYI0 PH and SEC7 domain-containing protein 3 chr8 GO:0005085 Not Cancer Driver No 86 0.0821394460362941 650 56 0.0534861509073543 0
PSD4-201 PSD4 Q8NDX1 PH and SEC7 domain-containing protein 4 chr2 GO:0005085 Not Cancer Driver No 128 0.1212121212121212 742 86 0.0814393939393939 0
PTGIR-201 PTGIR P43119 Prostacyclin receptor chr19 GO:0005085 Not Cancer Driver No 34 0.0880829015544041 47 3 0.0077720207253886 0
RAB3GAP1-201 RAB3GAP1 Q15042 Rab3 GTPase-activating protein catalytic subunit chr2 GO:0005085 Not Cancer Driver No 89 0.09072375127421 294 23 0.0234454638124362 2
RAB3GAP2-202 RAB3GAP2 Q9H2M9 Rab3 GTPase-activating protein non-catalytic subunit chr1 GO:0005085 Not Cancer Driver No 126 0.0904522613065326 143 12 0.0086145010768126 2
RAB3IL1-202 RAB3IL1 Q8TBN0 Guanine nucleotide exchange factor for Rab-3A chr11 GO:0005085 Not Cancer Driver No 34 0.0890052356020942 219 14 0.0366492146596858 0
RAB3IP-212 RAB3IP Q96QF0 Rab-3A-interacting protein chr12 GO:0005085 Not Cancer Driver No 70 0.1470588235294117 228 31 0.065126050420168 0
RABGEF1-201 RABGEF1 Q9UJ41 Rab5 GDP/GTP exchange factor chr7 GO:0005085 Not Cancer Driver No 59 0.120162932790224 175 27 0.054989816700611 0
RABIF-201 RABIF P47224 Guanine nucleotide exchange factor MSS4 chr1 GO:0005085 Not Cancer Driver No 11 0.089430894308943 25 3 0.024390243902439 0
RALGDS-202 RALGDS Q12967 Ral guanine nucleotide dissociation stimulator chr9 GO:0005085 Census, Compendium Yes 72 0.0787746170678337 382 28 0.0306345733041575 0
RALGPS1-201 RALGPS1 Q5JS13 Ras-specific guanine nucleotide-releasing factor RalGPS1 chr9 GO:0005085 Not Cancer Driver No 40 0.0718132854578097 219 19 0.0341113105924596 0
RALGPS2-204 RALGPS2 Q86X27 Ras-specific guanine nucleotide-releasing factor RalGPS2 chr1 GO:0005085 Not Cancer Driver No 67 0.1149228130360205 184 17 0.0291595197255574 0
RANGRF-201 RANGRF Q9HD47 Ran guanine nucleotide release factor chr17 GO:0005085 Not Cancer Driver No 6 0.032258064516129 42 3 0.0161290322580645 0
RAP1A-202 RAP1A P62834 Ras-related protein Rap-1A chr1 GO:0005085 Not Cancer Driver No 23 0.125 5 0 0.0 0
RAP1GDS1-205 RAP1GDS1 P52306 Rap1 GTPase-GDP dissociation stimulator 1 chr4 GO:0005085 Census, Compendium Yes 69 0.1136738056013179 13 0 0.0 0
RAPGEF1-201 RAPGEF1 Q13905 Rap guanine nucleotide exchange factor 1 chr9 GO:0005085 Not Cancer Driver No 119 0.1104921077065923 588 66 0.0612813370473537 0
RAPGEF2-201 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0005085 Not Cancer Driver No 132 0.0880587058038692 805 72 0.048032021347565 0
RAPGEF3-205 RAPGEF3 O95398 Rap guanine nucleotide exchange factor 3 chr12 GO:0005085 Not Cancer Driver No 79 0.085590465872156 197 18 0.0195016251354279 0
RAPGEF4-201 RAPGEF4 Q8WZA2 Rap guanine nucleotide exchange factor 4 chr2 GO:0005085 Not Cancer Driver No 113 0.1117705242334322 192 16 0.0158259149357072 0
RAPGEF5-202 RAPGEF5 Q92565 Rap guanine nucleotide exchange factor 5 chr7 GO:0005085 Not Cancer Driver No 50 0.0862068965517241 56 9 0.0155172413793103 0
RAPGEF6-208 RAPGEF6 Q8TEU7 Rap guanine nucleotide exchange factor 6 chr5 GO:0005085 Not Cancer Driver No 143 0.0893191755153029 790 72 0.0449718925671455 0
RAPGEFL1-211 RAPGEFL1 Q9UHV5 Rap guanine nucleotide exchange factor-like 1 chr17 GO:0005085 Not Cancer Driver No 36 0.0543806646525679 201 2 0.0030211480362537 0
RASGEF1A-204 RASGEF1A Q8N9B8 Ras-GEF domain-containing family member 1A chr10 GO:0005085 Not Cancer Driver No 48 0.0997920997920998 67 10 0.0207900207900207 0
RASGEF1B-201 RASGEF1B Q0VAM2 Ras-GEF domain-containing family member 1B chr4 GO:0005085 Not Cancer Driver No 43 0.0909090909090909 27 3 0.0063424947145877 0
RASGEF1C-201 RASGEF1C Q8N431 Ras-GEF domain-containing family member 1C chr5 GO:0005085 Not Cancer Driver No 65 0.1394849785407725 62 9 0.01931330472103 0
RASGRF1-202 RASGRF1 Q13972 Ras-specific guanine nucleotide-releasing factor 1 chr15 GO:0005085 Not Cancer Driver No 169 0.1327572663000785 333 53 0.0416339355852317 0
RASGRF2-201 RASGRF2 O14827 Ras-specific guanine nucleotide-releasing factor 2 chr5 GO:0005085 Not Cancer Driver No 158 0.1277283751010509 276 42 0.0339531123686337 0
RASGRP1-201 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0005085 Not Cancer Driver No 70 0.0878293601003764 192 11 0.013801756587202 1
RASGRP2-211 RASGRP2 Q7LDG7 RAS guanyl-releasing protein 2 chr11 GO:0005085 Not Cancer Driver No 76 0.1247947454844006 88 11 0.0180623973727422 4
RASGRP3-202 RASGRP3 Q8IV61 Ras guanyl-releasing protein 3 chr2 GO:0005085 Not Cancer Driver No 89 0.1289855072463768 148 14 0.0202898550724637 0
RASGRP4-214 RASGRP4 Q8TDF6 RAS guanyl-releasing protein 4 chr19 GO:0005085 Not Cancer Driver No 70 0.1040118870728083 180 34 0.050520059435364 0
RCBTB2-201 RCBTB2 O95199 RCC1 and BTB domain-containing protein 2 chr13 GO:0005085 Not Cancer Driver No 61 0.1107078039927404 37 3 0.0054446460980036 0
RCC1-214 RCC1 P18754 Regulator of chromosome condensation chr1 GO:0005085 Not Cancer Driver No 44 0.1045130641330166 146 16 0.0380047505938242 0
RCC1L-201 RCC1L Q96I51 RCC1-like G exchanging factor-like protein chr7 GO:0005085 Not Cancer Driver No 13 0.0280172413793103 87 6 0.0129310344827586 0
RCC2-202 RCC2 Q9P258 Protein RCC2 chr1 GO:0005085 Not Cancer Driver No 47 0.0900383141762452 194 20 0.0383141762452107 0
RGL1-202 RGL1 Q9NZL6 Ral guanine nucleotide dissociation stimulator-like 1 chr1 GO:0005085 Not Cancer Driver No 81 0.10546875 296 34 0.0442708333333333 0
RGL2-247 RGL2 O15211 Ral guanine nucleotide dissociation stimulator-like 2 chr6 GO:0005085 Not Cancer Driver No 67 0.0862290862290862 461 38 0.0489060489060489 0
RGL3-201 RGL3 Q3MIN7 Ral guanine nucleotide dissociation stimulator-like 3 chr19 GO:0005085 Compendium Yes 42 0.0591549295774647 401 22 0.0309859154929577 0
RGL4-201 RGL4 Q8IZJ4 Ral-GDS-related protein chr22 GO:0005085 Not Cancer Driver No 46 0.0972515856236786 177 18 0.0380549682875264 0
RGP1-201 RGP1 Q92546 RAB6A-GEF complex partner protein 2 chr9 GO:0005085 Not Cancer Driver No 32 0.0818414322250639 120 9 0.0230179028132992 0
RHOD-201 RHOD O00212 Rho-related GTP-binding protein RhoD chr11 GO:0005085 Not Cancer Driver No 16 0.0761904761904762 10 0 0.0 0
RHOF-201 RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 GO:0005085 Not Cancer Driver No 15 0.0710900473933649 11 0 0.0 0
RHOU-201 RHOU Q7L0Q8 Rho-related GTP-binding protein RhoU chr1 GO:0005085 Not Cancer Driver No 28 0.1085271317829457 63 6 0.0232558139534883 0
RIC1-203 RIC1 Q4ADV7 Guanine nucleotide exchange factor subunit RIC1 chr9 GO:0005085 Not Cancer Driver No 114 0.0801124385101897 253 17 0.0119465917076598 2
RIC8A-203 RIC8A Q9NPQ8 Synembryn-A chr11 GO:0005085 Not Cancer Driver No 54 0.1016949152542373 163 20 0.0376647834274952 0
RIC8B-203 RIC8B Q9NVN3 Synembryn-B chr12 GO:0005085 Not Cancer Driver No 43 0.0826923076923076 118 14 0.0269230769230769 0
RIN1-201 RIN1 Q13671 Ras and Rab interactor 1 chr11 GO:0005085 Not Cancer Driver No 65 0.0830140485312899 379 37 0.0472541507024265 0
RIN2-201 RIN2 Q8WYP3 Ras and Rab interactor 2 chr20 GO:0005085 Not Cancer Driver No 78 0.0871508379888268 296 25 0.0279329608938547 0
RIN3-201 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 GO:0005085 Not Cancer Driver No 64 0.0649746192893401 420 31 0.0314720812182741 0
RINL-202 RINL Q6ZS11 Ras and Rab interactor-like protein chr19 GO:0005085 Not Cancer Driver No 27 0.0477031802120141 367 18 0.0318021201413427 0
RPGR-201 RPGR Q92834 X-linked retinitis pigmentosa GTPase regulator chrX GO:0005085 Not Cancer Driver No 59 0.0578431372549019 643 29 0.0284313725490196 20
SBF1-241 SBF1 O95248 Myotubularin-related protein 5 chr22 GO:0005085 Not Cancer Driver No 165 0.0883297644539614 633 50 0.0267665952890792 2
SBF2-201 SBF2 Q86WG5 Myotubularin-related protein 13 chr11 GO:0005085 Not Cancer Driver No 140 0.075716603569497 367 37 0.0200108166576527 0
SERGEF-201 SERGEF Q9UGK8 Secretion-regulating guanine nucleotide exchange factor chr11 GO:0005085 Not Cancer Driver No 38 0.0829694323144104 92 6 0.0131004366812227 0
SH2D3A-201 SH2D3A Q9BRG2 SH2 domain-containing protein 3A chr19 GO:0005085 Not Cancer Driver No 52 0.0902777777777777 308 30 0.0520833333333333 0
SH2D3C-201 SH2D3C Q8N5H7 SH2 domain-containing protein 3C chr9 GO:0005085 Not Cancer Driver No 81 0.0941860465116279 443 52 0.0604651162790697 0
SH3BP5-202 SH3BP5 O60239 SH3 domain-binding protein 5 chr3 GO:0005085 Not Cancer Driver No 33 0.0725274725274725 380 23 0.0505494505494505 0
SH3BP5L-201 SH3BP5L Q7L8J4 SH3 domain-binding protein 5-like chr1 GO:0005085 Not Cancer Driver No 47 0.1195928753180661 376 44 0.1119592875318066 0
SLC38A9-202 SLC38A9 Q8NBW4 Neutral amino acid transporter 9 chr5 GO:0005085 Not Cancer Driver No 41 0.0730837789661319 33 1 0.0017825311942959 0
SMCR8-201 SMCR8 Q8TEV9 Guanine nucleotide exchange protein SMCR8 chr17 GO:0005085 Not Cancer Driver No 76 0.0811099252934898 357 30 0.032017075773746 0
SOS1-202 SOS1 Q07889 Son of sevenless homolog 1 chr2 GO:0005085 Compendium Yes 155 0.1162790697674418 459 47 0.0352588147036759 32
SOS2-201 SOS2 Q07890 Son of sevenless homolog 2 chr14 GO:0005085 Not Cancer Driver No 123 0.0923423423423423 362 44 0.033033033033033 2
SPATA13-202 SPATA13 Q96N96 Spermatogenesis-associated protein 13 chr13 GO:0005085 Not Cancer Driver No 46 0.0705521472392638 264 22 0.0337423312883435 0
SWAP70-201 SWAP70 Q9UH65 Switch-associated protein 70 chr11 GO:0005085 Not Cancer Driver No 33 0.0564102564102564 274 10 0.017094017094017 0
TAGAP-203 TAGAP Q8N103 T-cell activation Rho GTPase-activating protein chr6 GO:0005085 Not Cancer Driver No 80 0.1094391244870041 458 57 0.0779753761969904 0
TBC1D10A-201 TBC1D10A Q9BXI6 TBC1 domain family member 10A chr22 GO:0005085 Not Cancer Driver No 54 0.1062992125984252 210 22 0.0433070866141732 0
TBXA2R-201 TBXA2R P21731 Thromboxane A2 receptor chr19 GO:0005085 Not Cancer Driver No 42 0.1224489795918367 17 3 0.0087463556851311 1
THG1L-201 THG1L Q9NWX6 Probable tRNA(His) guanylyltransferase chr5 GO:0005085 Not Cancer Driver No 20 0.0671140939597315 22 2 0.0067114093959731 1
TIAM1-206 TIAM1 Q13009 Rho guanine nucleotide exchange factor TIAM1 chr21 GO:0005085 Not Cancer Driver No 263 0.1653048397234443 813 147 0.092394720301697 0
TIAM2-220 TIAM2 Q8IVF5 Rho guanine nucleotide exchange factor TIAM2 chr6 GO:0005085 Not Cancer Driver No 239 0.1405055849500294 785 130 0.0764256319811875 0
TRIO-202 TRIO O75962 Triple functional domain protein chr5 GO:0005085 Not Cancer Driver No 303 0.0978366160800774 1054 88 0.0284145947691314 8
VAV1-210 VAV1 P15498 Proto-oncogene vav chr19 GO:0005085 Census, Compendium Yes 128 0.1514792899408284 113 18 0.0213017751479289 0
VAV2-201 VAV2 P52735 Guanine nucleotide exchange factor VAV2 chr9 GO:0005085 Not Cancer Driver No 85 0.0968109339407744 136 15 0.0170842824601366 0
VAV3-202 VAV3 Q9UKW4 Guanine nucleotide exchange factor VAV3 chr1 GO:0005085 Not Cancer Driver No 118 0.1393152302243211 102 16 0.0188902007083825 0
VPS9D1-201 VPS9D1 Q9Y2B5 VPS9 domain-containing protein 1 chr16 GO:0005085 Not Cancer Driver No 47 0.0744849445324881 356 24 0.0380348652931854 0
WDR41-201 WDR41 Q9HAD4 WD repeat-containing protein 41 chr5 GO:0005085 Not Cancer Driver No 34 0.074074074074074 23 2 0.0043572984749455 0