Total number of protein in "GO:0005546" GO term: 85
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACTN2-201 | ACTN2 | P35609 | Alpha-actinin-2 | chr1 | GO:0005546 | Not Cancer Driver | No | 191 | 0.2136465324384787 | 129 | 23 | 0.0257270693512304 | 9 |
| ADAP2-201 | ADAP2 | Q9NPF8 | Arf-GAP with dual PH domain-containing protein 2 | chr17 | GO:0005546 | Not Cancer Driver | No | 37 | 0.0971128608923884 | 30 | 5 | 0.0131233595800524 | 0 |
| ALOX15-201 | ALOX15 | P16050 | Polyunsaturated fatty acid lipoxygenase ALOX15 | chr17 | GO:0005546 | Not Cancer Driver | No | 64 | 0.0966767371601208 | 46 | 4 | 0.0060422960725075 | 0 |
| AMER1-201 | AMER1 | Q5JTC6 | APC membrane recruitment protein 1 | chrX | GO:0005546 | Census, Compendium | Yes | 196 | 0.1726872246696035 | 1041 | 185 | 0.1629955947136563 | 0 |
| AMER2-202 | AMER2 | Q8N7J2 | APC membrane recruitment protein 2 | chr13 | GO:0005546 | Not Cancer Driver | No | 90 | 0.1341281669150521 | 663 | 88 | 0.1311475409836065 | 0 |
| AMER3-201 | AMER3 | Q8N944 | APC membrane recruitment protein 3 | chr2 | GO:0005546 | Not Cancer Driver | No | 198 | 0.229965156794425 | 737 | 173 | 0.2009291521486643 | 0 |
| ANXA2-204 | ANXA2 | P07355 | Annexin A2 | chr15 | GO:0005546 | Not Cancer Driver | No | 38 | 0.1120943952802359 | 21 | 2 | 0.0058997050147492 | 0 |
| ANXA8-205 | ANXA8 | P13928 | Annexin A8 | chr10 | GO:0005546 | Not Cancer Driver | No | 0 | 0.0 | 40 | 0 | 0.0 | 0 |
| ASAP1-202 | ASAP1 | Q9ULH1 | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 | chr8 | GO:0005546 | Not Cancer Driver | No | 132 | 0.1169176262178919 | 587 | 79 | 0.0699734278122232 | 0 |
| AVIL-207 | AVIL | O75366 | Advillin | chr12 | GO:0005546 | Not Cancer Driver | No | 59 | 0.072039072039072 | 139 | 12 | 0.0146520146520146 | 2 |
| CAPG-201 | CAPG | P40121 | Macrophage-capping protein | chr2 | GO:0005546 | Not Cancer Driver | No | 35 | 0.1005747126436781 | 96 | 6 | 0.0172413793103448 | 0 |
| CGAS-201 | CGAS | Q8N884 | Cyclic GMP-AMP synthase | chr6 | GO:0005546 | Not Cancer Driver | No | 33 | 0.0632183908045977 | 175 | 6 | 0.0114942528735632 | 0 |
| CHMP3-201 | CHMP3 | Q9Y3E7 | Charged multivesicular body protein 3 | chr2 | GO:0005546 | Not Cancer Driver | No | 18 | 0.081081081081081 | 138 | 10 | 0.045045045045045 | 0 |
| COMMD1-201 | COMMD1 | Q8N668 | COMM domain-containing protein 1 | chr2 | GO:0005546 | Not Cancer Driver | No | 17 | 0.0894736842105263 | 17 | 0 | 0.0 | 0 |
| DEFB4A-201 | DEFB4B | O15263 | Defensin beta 4A | chr8 | GO:0005546 | Not Cancer Driver | No | 0 | 0.0 | 0 | 0 | 0.0 | 0 |
| DEFB4B-201 | DEFB4B | O15263 | Defensin beta 4A | chr8 | GO:0005546 | Not Cancer Driver | No | 0 | 0.0 | 0 | 0 | 0.0 | 0 |
| DNM1-202 | DNM1 | Q05193 | Dynamin-1 | chr9 | GO:0005546 | Not Cancer Driver | No | 75 | 0.0868055555555555 | 280 | 19 | 0.0219907407407407 | 4 |
| DNM2-201 | DNM2 | P50570 | Dynamin-2 | chr19 | GO:0005546 | Census | Yes | 95 | 0.1091954022988505 | 271 | 32 | 0.0367816091954023 | 16 |
| EXOC1-203 | EXOC1 | Q9NV70 | Exocyst complex component 1 | chr4 | GO:0005546 | Not Cancer Driver | No | 83 | 0.0928411633109619 | 154 | 14 | 0.0156599552572706 | 0 |
| EXOC7-202 | EXOC7 | Q9UPT5 | Exocyst complex component 7 | chr17 | GO:0005546 | Not Cancer Driver | No | 79 | 0.1074829931972789 | 209 | 22 | 0.0299319727891156 | 0 |
| FCHO2-202 | FCHO2 | Q0JRZ9 | F-BAR domain only protein 2 | chr5 | GO:0005546 | Not Cancer Driver | No | 45 | 0.0555555555555555 | 375 | 22 | 0.0271604938271604 | 0 |
| FLII-201 | FLII | Q13045 | Protein flightless-1 homolog | chr17 | GO:0005546 | Not Cancer Driver | No | 95 | 0.0748620961386918 | 206 | 20 | 0.0157604412923561 | 0 |
| FRMPD4-201 | FRMPD4 | Q14CM0 | FERM and PDZ domain-containing protein 4 | chrX | GO:0005546 | Not Cancer Driver | No | 228 | 0.172465960665658 | 795 | 150 | 0.113464447806354 | 1 |
| FZD7-201 | FZD7 | O75084 | Frizzled-7 | chr2 | GO:0005546 | Not Cancer Driver | No | 72 | 0.1254355400696864 | 22 | 1 | 0.0017421602787456 | 0 |
| GRAMD2A-201 | GRAMD2A | Q8IUY3 | GRAM domain-containing protein 2A | chr15 | GO:0005546 | Not Cancer Driver | No | 32 | 0.0903954802259887 | 107 | 4 | 0.0112994350282485 | 0 |
| GSDMA-201 | GSDMA | Q96QA5 | Gasdermin-A | chr17 | GO:0005546 | Not Cancer Driver | No | 55 | 0.1235955056179775 | 88 | 14 | 0.0314606741573033 | 0 |
| GSDMB-205 | GSDMB | Q8TAX9 | Gasdermin-B | chr17 | GO:0005546 | Not Cancer Driver | No | 32 | 0.0769230769230769 | 84 | 8 | 0.0192307692307692 | 0 |
| GSDMC-201 | GSDMC | Q9BYG8 | Gasdermin-C | chr8 | GO:0005546 | Not Cancer Driver | No | 93 | 0.1830708661417323 | 0 | 0 | 0.0 | 0 |
| GSDMD-201 | GSDMD | P57764 | Gasdermin-D | chr8 | GO:0005546 | Not Cancer Driver | No | 38 | 0.0785123966942148 | 156 | 14 | 0.0289256198347107 | 0 |
| GSDME-214 | GSDME | O60443 | Gasdermin-E | chr7 | GO:0005546 | Not Cancer Driver | No | 64 | 0.1290322580645161 | 14 | 2 | 0.0040322580645161 | 0 |
| GSN-204 | GSN | P06396 | Gelsolin | chr9 | GO:0005546 | Not Cancer Driver | No | 51 | 0.0652173913043478 | 318 | 18 | 0.0230179028132992 | 1 |
| HIP1-201 | HIP1 | O00291 | Huntingtin-interacting protein 1 | chr7 | GO:0005546 | Census, Compendium | Yes | 118 | 0.1137897782063645 | 514 | 60 | 0.0578592092574734 | 0 |
| HIP1R-201 | HIP1R | O75146 | Huntingtin-interacting protein 1-related protein | chr12 | GO:0005546 | Not Cancer Driver | No | 73 | 0.0683520599250936 | 527 | 30 | 0.0280898876404494 | 0 |
| JPH2-202 | JPH2 | Q9BR39 | Junctophilin-2 | chr20 | GO:0005546 | Not Cancer Driver | No | 107 | 0.153735632183908 | 545 | 75 | 0.1077586206896551 | 6 |
| KCNJ1-202 | KCNJ1 | P48048 | ATP-sensitive inward rectifier potassium channel 1 | chr11 | GO:0005546 | Not Cancer Driver | No | 70 | 0.1790281329923273 | 10 | 0 | 0.0 | 13 |
| KCNJ2-201 | KCNJ2 | P63252 | Inward rectifier potassium channel 2 | chr17 | GO:0005546 | Not Cancer Driver | No | 85 | 0.1990632318501171 | 49 | 7 | 0.0163934426229508 | 12 |
| KCNQ1-201 | KCNQ1 | P51787 | Potassium voltage-gated channel subfamily KQT member 1 | chr11 | GO:0005546 | Not Cancer Driver | No | 55 | 0.0813609467455621 | 219 | 14 | 0.0207100591715976 | 109 |
| KRIT1-203 | KRIT1 | O00522 | Krev interaction trapped protein 1 | chr7 | GO:0005546 | Not Cancer Driver | No | 65 | 0.0883152173913043 | 113 | 16 | 0.0217391304347826 | 2 |
| LDLRAP1-201 | LDLRAP1 | Q5SW96 | Low density lipoprotein receptor adapter protein 1 | chr1 | GO:0005546 | Not Cancer Driver | No | 29 | 0.0941558441558441 | 121 | 9 | 0.0292207792207792 | 2 |
| MAPKAP1-201 | MAPKAP1 | Q9BPZ7 | Target of rapamycin complex 2 subunit MAPKAP1 | chr9 | GO:0005546 | Not Cancer Driver | No | 57 | 0.1091954022988505 | 173 | 17 | 0.0325670498084291 | 0 |
| MARK1-201 | MARK1 | Q9P0L2 | Serine/threonine-protein kinase MARK1 | chr1 | GO:0005546 | Not Cancer Driver | No | 129 | 0.1622641509433962 | 454 | 81 | 0.1018867924528302 | 0 |
| MTSS2-201 | MTSS2 | Q765P7 | Protein MTSS 2 | chr16 | GO:0005546 | Not Cancer Driver | No | 53 | 0.0709504685408299 | 584 | 41 | 0.0548862115127175 | 1 |
| MYO1B-204 | MYO1B | O43795 | Unconventional myosin-Ib | chr2 | GO:0005546 | Not Cancer Driver | No | 103 | 0.090669014084507 | 35 | 3 | 0.0026408450704225 | 0 |
| MYO1G-201 | MYO1G | B0I1T2 | Unconventional myosin-Ig | chr7 | GO:0005546 | Not Cancer Driver | No | 98 | 0.0962671905697446 | 117 | 12 | 0.0117878192534381 | 0 |
| OBSCN-204 | OBSCN | Q5VST9 | Obscurin | chr1 | GO:0005546 | Not Cancer Driver | No | 914 | 0.1147088353413654 | 2651 | 286 | 0.0358935742971887 | 0 |
| OSBPL2-201 | OSBPL2 | Q9H1P3 | Oxysterol-binding protein-related protein 2 | chr20 | GO:0005546 | Not Cancer Driver | No | 40 | 0.0833333333333333 | 173 | 15 | 0.03125 | 0 |
| PARD3-208 | PARD3 | Q8TEW0 | Partitioning defective 3 homolog | chr10 | GO:0005546 | Not Cancer Driver | No | 148 | 0.1091445427728613 | 1147 | 128 | 0.0943952802359882 | 2 |
| PFN1-201 | PFN1 | P07737 | Profilin-1 | chr17 | GO:0005546 | Not Cancer Driver | No | 13 | 0.0928571428571428 | 7 | 1 | 0.0071428571428571 | 3 |
| PFN2-201 | PFN2 | P35080 | Profilin-2 | chr3 | GO:0005546 | Not Cancer Driver | No | 11 | 0.0785714285714285 | 0 | 0 | 0.0 | 0 |
| PHLDA3-202 | PHLDA3 | Q9Y5J5 | Pleckstrin homology-like domain family A member 3 | chr1 | GO:0005546 | Not Cancer Driver | No | 14 | 0.1102362204724409 | 0 | 0 | 0.0 | 0 |
| PICALM-202 | PICALM | Q13492 | Phosphatidylinositol-binding clathrin assembly protein | chr11 | GO:0005546 | Census | Yes | 64 | 0.0981595092024539 | 320 | 31 | 0.0475460122699386 | 0 |
| PLA2G4E-201 | PLA2G4E | Q3MJ16 | Cytosolic phospholipase A2 epsilon | chr15 | GO:0005546 | Not Cancer Driver | No | 51 | 0.0587557603686636 | 125 | 5 | 0.0057603686635944 | 0 |
| PLCB1-201 | PLCB1 | Q9NQ66 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 | chr20 | GO:0005546 | Not Cancer Driver | No | 264 | 0.2171052631578947 | 484 | 85 | 0.0699013157894736 | 0 |
| PLCD1-201 | PLCD1 | P51178 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 | chr3 | GO:0005546 | Not Cancer Driver | No | 66 | 0.0873015873015873 | 113 | 12 | 0.0158730158730158 | 2 |
| PLCZ1-201 | PLCZ1 | Q86YW0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 | chr12 | GO:0005546 | Not Cancer Driver | No | 121 | 0.1990131578947368 | 37 | 19 | 0.03125 | 1 |
| PLEKHA4-201 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | GO:0005546 | Not Cancer Driver | No | 115 | 0.1476251604621309 | 690 | 110 | 0.1412066752246469 | 0 |
| RAB35-201 | RAB35 | Q15286 | Ras-related protein Rab-35 | chr12 | GO:0005546 | Not Cancer Driver | No | 16 | 0.0796019900497512 | 26 | 1 | 0.0049751243781094 | 0 |
| RAG2-201 | RAG2 | P55895 | V(D)J recombination-activating protein 2 | chr11 | GO:0005546 | Not Cancer Driver | No | 87 | 0.1650853889943074 | 86 | 18 | 0.0341555977229601 | 6 |
| RPH3A-201 | RPH3A | Q9Y2J0 | Rabphilin-3A | chr12 | GO:0005546 | Not Cancer Driver | No | 140 | 0.2017291066282421 | 430 | 99 | 0.1426512968299711 | 0 |
| SCIN-201 | SCIN | Q9Y6U3 | Scinderin | chr7 | GO:0005546 | Not Cancer Driver | No | 61 | 0.0853146853146853 | 170 | 17 | 0.0237762237762237 | 0 |
| SDCBP-201 | SDCBP | O00560 | Syntenin-1 | chr8 | GO:0005546 | Not Cancer Driver | No | 23 | 0.0771812080536912 | 17 | 1 | 0.0033557046979865 | 0 |
| SDCBP2-202 | SDCBP2 | Q9H190 | Syntenin-2 | chr20 | GO:0005546 | Not Cancer Driver | No | 36 | 0.1232876712328767 | 69 | 8 | 0.0273972602739726 | 0 |
| SESTD1-203 | SESTD1 | Q86VW0 | SEC14 domain and spectrin repeat-containing protein 1 | chr2 | GO:0005546 | Not Cancer Driver | No | 73 | 0.1048850574712643 | 127 | 12 | 0.0172413793103448 | 0 |
| SH3PXD2A-203 | SH3PXD2A | Q5TCZ1 | SH3 and PX domain-containing protein 2A | chr10 | GO:0005546 | Not Cancer Driver | No | 111 | 0.0979699911738746 | 802 | 86 | 0.0759046778464254 | 0 |
| SLC9A1-201 | SLC9A1 | P19634 | Sodium/hydrogen exchanger 1 | chr1 | GO:0005546 | Not Cancer Driver | No | 57 | 0.0699386503067484 | 252 | 17 | 0.0208588957055214 | 1 |
| SNAP91-204 | SNAP91 | O60641 | Clathrin coat assembly protein AP180 | chr6 | GO:0005546 | Not Cancer Driver | No | 152 | 0.1675854465270121 | 638 | 94 | 0.103638368246968 | 0 |
| SNX18-202 | SNX18 | Q96RF0 | Sorting nexin-18 | chr5 | GO:0005546 | Not Cancer Driver | No | 39 | 0.0621019108280254 | 238 | 4 | 0.0063694267515923 | 0 |
| SNX20-202 | SNX20 | Q7Z614 | Sorting nexin-20 | chr16 | GO:0005546 | Not Cancer Driver | No | 46 | 0.1455696202531645 | 73 | 9 | 0.0284810126582278 | 0 |
| SNX21-212 | SNX21 | Q969T3 | Sorting nexin-21 | chr20 | GO:0005546 | Not Cancer Driver | No | 18 | 0.0482573726541554 | 180 | 7 | 0.0187667560321715 | 0 |
| SVIL-201 | SVIL | O95425 | Supervillin | chr10 | GO:0005546 | Not Cancer Driver | No | 245 | 0.1106594399277326 | 1434 | 151 | 0.0682023486901535 | 0 |
| SYT1-201 | SYT1 | P21579 | Synaptotagmin-1 | chr12 | GO:0005546 | Not Cancer Driver | No | 89 | 0.2109004739336493 | 103 | 33 | 0.0781990521327014 | 5 |
| SYT10-201 | SYT10 | Q6XYQ8 | Synaptotagmin-10 | chr12 | GO:0005546 | Not Cancer Driver | No | 128 | 0.2447418738049713 | 164 | 47 | 0.0898661567877629 | 0 |
| SYT5-201 | SYT5 | O00445 | Synaptotagmin-5 | chr19 | GO:0005546 | Not Cancer Driver | No | 46 | 0.1191709844559585 | 111 | 8 | 0.0207253886010362 | 0 |
| SYT7-201 | SYT7 | O43581 | Synaptotagmin-7 | chr11 | GO:0005546 | Not Cancer Driver | No | 50 | 0.1240694789081885 | 132 | 19 | 0.0471464019851116 | 0 |
| SYT9-201 | SYT9 | Q86SS6 | Synaptotagmin-9 | chr11 | GO:0005546 | Not Cancer Driver | No | 95 | 0.1934826883910387 | 149 | 32 | 0.065173116089613 | 0 |
| SYTL2-216 | SYTL2 | Q9HCH5 | Synaptotagmin-like protein 2 | chr11 | GO:0005546 | Not Cancer Driver | No | 99 | 0.1059957173447537 | 632 | 77 | 0.082441113490364 | 0 |
| TIRAP-202 | TIRAP | P58753 | Toll/interleukin-1 receptor domain-containing adapter protein | chr11 | GO:0005546 | Not Cancer Driver | No | 14 | 0.0633484162895927 | 80 | 5 | 0.0226244343891402 | 0 |
| TTPA-201 | TTPA | P49638 | Alpha-tocopherol transfer protein | chr8 | GO:0005546 | Not Cancer Driver | No | 45 | 0.1618705035971223 | 21 | 1 | 0.0035971223021582 | 7 |
| TULP1-201 | TULP1 | O00294 | Tubby-related protein 1 | chr6 | GO:0005546 | Not Cancer Driver | No | 80 | 0.1476014760147601 | 379 | 56 | 0.1033210332103321 | 12 |
| TULP3-202 | TULP3 | O75386 | Tubby-related protein 3 | chr12 | GO:0005546 | Not Cancer Driver | No | 54 | 0.1221719457013574 | 218 | 26 | 0.0588235294117647 | 1 |
| TWF1-201 | TWF1 | Q12792 | Twinfilin-1 | chr12 | GO:0005546 | Not Cancer Driver | No | 25 | 0.0714285714285714 | 52 | 1 | 0.0028571428571428 | 0 |
| TWF2-201 | TWF2 | Q6IBS0 | Twinfilin-2 | chr3 | GO:0005546 | Not Cancer Driver | No | 28 | 0.0802292263610315 | 59 | 8 | 0.0229226361031518 | 0 |
| VIL1-201 | VIL1 | P09327 | Villin-1 | chr2 | GO:0005546 | Not Cancer Driver | No | 90 | 0.1088270858524788 | 222 | 26 | 0.0314389359129383 | 0 |
| VILL-202 | VILL | O15195 | Villin-like protein | chr3 | GO:0005546 | Not Cancer Driver | No | 81 | 0.094626168224299 | 224 | 22 | 0.0257009345794392 | 0 |
| WASHC2C-209 | WASHC2C | Q9Y4E1 | WASH complex subunit 2C | chr10 | GO:0005546 | Not Cancer Driver | No | 65 | 0.0484712900820283 | 1225 | 64 | 0.0477255779269202 | 0 |