Total number of protein in "GO:0006270" GO term: 27
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CCNE1-201 | CCNE1 | P24864 | G1/S-specific cyclin-E1 | chr19 | GO:0006270 | Census | Yes | 44 | 0.1073170731707317 | 142 | 15 | 0.0365853658536585 | 0 |
| CCNE2-201 | CCNE2 | O96020 | G1/S-specific cyclin-E2 | chr8 | GO:0006270 | Not Cancer Driver | No | 35 | 0.0866336633663366 | 69 | 9 | 0.0222772277227722 | 0 |
| CDC34-201 | CDC34 | P49427 | Ubiquitin-conjugating enzyme E2 R1 | chr19 | GO:0006270 | Not Cancer Driver | No | 19 | 0.0805084745762711 | 96 | 7 | 0.0296610169491525 | 0 |
| CDC45-201 | CDC45 | O75419 | Cell division control protein 45 homolog | chr22 | GO:0006270 | Not Cancer Driver | No | 49 | 0.0865724381625441 | 66 | 12 | 0.0212014134275618 | 5 |
| CDC6-201 | CDC6 | Q99741 | Cell division control protein 6 homolog | chr17 | GO:0006270 | Not Cancer Driver | No | 48 | 0.0857142857142857 | 170 | 15 | 0.0267857142857142 | 1 |
| ENST00000649896 | POLA2 | Q14181 | DNA polymerase alpha subunit B | chr11 | GO:0006270 | Not Cancer Driver | No | 45 | 0.0774526678141136 | 121 | 15 | 0.0258175559380378 | 0 |
| LRWD1-201 | LRWD1 | Q9UFC0 | Leucine-rich repeat and WD repeat-containing protein 1 | chr7 | GO:0006270 | Not Cancer Driver | No | 46 | 0.071097372488408 | 133 | 9 | 0.0139103554868624 | 0 |
| MCM10-206 | MCM10 | Q7L590 | Protein MCM10 homolog | chr10 | GO:0006270 | Not Cancer Driver | No | 111 | 0.1268571428571428 | 538 | 75 | 0.0857142857142857 | 1 |
| MCM2-201 | MCM2 | P49736 | DNA replication licensing factor MCM2 | chr3 | GO:0006270 | Not Cancer Driver | No | 77 | 0.0851769911504424 | 277 | 33 | 0.036504424778761 | 1 |
| MCM3-205 | MCM3 | P25205 | DNA replication licensing factor MCM3 | chr6 | GO:0006270 | Not Cancer Driver | No | 58 | 0.0717821782178217 | 310 | 28 | 0.0346534653465346 | 0 |
| MCM5-201 | MCM5 | P33992 | DNA replication licensing factor MCM5 | chr22 | GO:0006270 | Not Cancer Driver | No | 68 | 0.0926430517711171 | 110 | 15 | 0.0204359673024523 | 1 |
| MCM6-201 | MCM6 | Q14566 | DNA replication licensing factor MCM6 | chr2 | GO:0006270 | Not Cancer Driver | No | 78 | 0.0950060901339829 | 122 | 11 | 0.0133982947624847 | 0 |
| MCM7-201 | MCM7 | P33993 | DNA replication licensing factor MCM7 | chr7 | GO:0006270 | Not Cancer Driver | No | 75 | 0.1043115438108484 | 128 | 16 | 0.0222531293463143 | 0 |
| NOC3L-201 | NOC3L | Q8WTT2 | Nucleolar complex protein 3 homolog | chr10 | GO:0006270 | Not Cancer Driver | No | 49 | 0.06125 | 284 | 21 | 0.02625 | 0 |
| ORC1-202 | ORC1 | Q13415 | Origin recognition complex subunit 1 | chr1 | GO:0006270 | Not Cancer Driver | No | 72 | 0.0836236933797909 | 340 | 30 | 0.0348432055749128 | 5 |
| ORC2-201 | ORC2 | Q13416 | Origin recognition complex subunit 2 | chr2 | GO:0006270 | Not Cancer Driver | No | 44 | 0.0762564991334488 | 249 | 13 | 0.022530329289428 | 0 |
| ORC3-202 | ORC3 | Q9UBD5 | Origin recognition complex subunit 3 | chr6 | GO:0006270 | Not Cancer Driver | No | 45 | 0.0632911392405063 | 64 | 4 | 0.0056258790436005 | 0 |
| ORC4-202 | ORC4 | O43929 | Origin recognition complex subunit 4 | chr2 | GO:0006270 | Not Cancer Driver | No | 36 | 0.0825688073394495 | 14 | 1 | 0.0022935779816513 | 1 |
| ORC5-201 | ORC5 | O43913 | Origin recognition complex subunit 5 | chr7 | GO:0006270 | Not Cancer Driver | No | 27 | 0.0620689655172413 | 16 | 2 | 0.0045977011494252 | 0 |
| ORC6-201 | ORC6 | Q9Y5N6 | Origin recognition complex subunit 6 | chr16 | GO:0006270 | Not Cancer Driver | No | 20 | 0.0793650793650793 | 69 | 9 | 0.0357142857142857 | 1 |
| POLA1-201 | POLA1 | P09884 | DNA polymerase alpha catalytic subunit | chrX | GO:0006270 | Not Cancer Driver | No | 113 | 0.0772913816689466 | 347 | 30 | 0.0205198358413132 | 3 |
| POLA2-201 | POLA2 | Q14181 | DNA polymerase alpha subunit B | chr11 | GO:0006270 | Not Cancer Driver | No | 49 | 0.0819397993311036 | 102 | 15 | 0.0250836120401337 | 0 |
| PRIM1-201 | PRIM1 | P49642 | DNA primase small subunit | chr12 | GO:0006270 | Not Cancer Driver | No | 27 | 0.0642857142857142 | 22 | 1 | 0.0023809523809523 | 1 |
| PRIM2-207 | PRIM2 | P49643 | DNA primase large subunit | chr6 | GO:0006270 | Not Cancer Driver | No | 27 | 0.0530451866404715 | 69 | 0 | 0.0 | 0 |
| PURA-201 | PURA | Q00577 | Transcriptional activator protein Pur-alpha | chr5 | GO:0006270 | Not Cancer Driver | No | 17 | 0.0527950310559006 | 188 | 6 | 0.0186335403726708 | 6 |
| RPA4-201 | RPA4 | Q13156 | Replication protein A 30 kDa subunit | chrX | GO:0006270 | Not Cancer Driver | No | 56 | 0.21455938697318 | 59 | 10 | 0.0383141762452107 | 0 |
| TOPBP1-201 | TOPBP1 | Q92547 | DNA topoisomerase 2-binding protein 1 | chr3 | GO:0006270 | Not Cancer Driver | No | 121 | 0.0795006570302234 | 579 | 43 | 0.0282522996057818 | 0 |