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Total number of protein in "GO:0006281" GO term:  247

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACTL6A-202 ACTL6A O96019 Actin-like protein 6A chr3 GO:0006281 Not Cancer Driver No 39 0.0909090909090909 74 8 0.0186480186480186 1
ADPRS-201 ADPRS Q9NX46 ADP-ribosylhydrolase ARH3 chr1 GO:0006281 Not Cancer Driver No 23 0.0633608815426997 49 2 0.0055096418732782 1
ALKBH1-201 ALKBH1 Q13686 Nucleic acid dioxygenase ALKBH1 chr14 GO:0006281 Not Cancer Driver No 45 0.1156812339331619 78 9 0.0231362467866323 0
ALKBH3-201 ALKBH3 Q96Q83 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 chr11 GO:0006281 Not Cancer Driver No 30 0.1048951048951049 160 18 0.0629370629370629 0
APEX1-201 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 GO:0006281 Not Cancer Driver No 23 0.0723270440251572 104 9 0.0283018867924528 0
APLF-201 APLF Q8IW19 Aprataxin and PNK-like factor chr2 GO:0006281 Not Cancer Driver No 43 0.0841487279843444 411 37 0.0724070450097847 0
ASF1A-201 ASF1A Q9Y294 Histone chaperone ASF1A chr6 GO:0006281 Not Cancer Driver No 11 0.0539215686274509 69 2 0.0098039215686274 0
ATR-201 ATR Q13535 Serine/threonine-protein kinase ATR chr3 GO:0006281 Census, Compendium Yes 261 0.098714069591528 107 11 0.0041603630862329 1
ATRIP-201 ATRIP Q8WXE1 ATR-interacting protein chr3 GO:0006281 Not Cancer Driver No 50 0.0632111251580278 388 22 0.0278128950695322 0
ATRX-201 ATRX P46100 Transcriptional regulator ATRX chrX GO:0006281 Census, Compendium Yes 306 0.1227929373996789 1673 173 0.069422150882825 29
BACH1-201 BACH1 O14867 Transcription regulator protein BACH1 chr21 GO:0006281 Not Cancer Driver No 79 0.1073369565217391 328 34 0.046195652173913 0
BARD1-201 BARD1 Q99728 BRCA1-associated RING domain protein 1 chr2 GO:0006281 Census Yes 71 0.0913770913770913 390 39 0.0501930501930501 0
BCCIP-201 BCCIP Q9P287 BRCA2 and CDKN1A-interacting protein chr10 GO:0006281 Not Cancer Driver No 23 0.0732484076433121 99 13 0.0414012738853503 0
BLM-201 BLM P54132 RecQ-like DNA helicase BLM chr15 GO:0006281 Census Yes 112 0.0790402258292166 671 53 0.0374029640084686 9
BOD1L1-201 BOD1L1 Q8NFC6 Biorientation of chromosomes in cell division protein 1-like 1 chr4 GO:0006281 Not Cancer Driver No 276 0.0904621435594886 3030 276 0.0904621435594886 0
BRCA1-203 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0006281 Census, Compendium Yes 167 0.0896403650026838 1466 127 0.0681696188942565 34
BRIP1-201 BRIP1 Q9BX63 Fanconi anemia group J protein chr17 GO:0006281 Census Yes 118 0.0944755804643715 399 41 0.032826261008807 6
BTG2-201 BTG2 P78543 Protein BTG2 chr1 GO:0006281 Census Yes 30 0.189873417721519 7 2 0.0126582278481012 0
CDC14B-202 CDC14B O60729 Dual specificity protein phosphatase CDC14B chr9 GO:0006281 Not Cancer Driver No 46 0.0923694779116465 138 10 0.0200803212851405 0
CDC5L-201 CDC5L Q99459 Cell division cycle 5-like protein chr6 GO:0006281 Not Cancer Driver No 60 0.0748129675810473 621 46 0.0573566084788029 0
CDK1-203 CDK1 P06493 Cyclin-dependent kinase 1 chr10 GO:0006281 Not Cancer Driver No 26 0.0875420875420875 1 0 0.0 0
CDK2-201 CDK2 P24941 Cyclin-dependent kinase 2 chr12 GO:0006281 Not Cancer Driver No 17 0.0570469798657718 0 0 0.0 0
CDK7-201 CDK7 P50613 Cyclin-dependent kinase 7 chr5 GO:0006281 Not Cancer Driver No 25 0.0722543352601156 38 3 0.0086705202312138 0
CDK9-201 CDK9 P50750 Cyclin-dependent kinase 9 chr9 GO:0006281 Not Cancer Driver No 40 0.1075268817204301 34 2 0.0053763440860215 0
CENPS-201 CENPS Q8N2Z9 Centromere protein S chr1 GO:0006281 Not Cancer Driver No 6 0.0434782608695652 66 2 0.0144927536231884 0
CENPS-CORT-205 CENPS Q8N2Z9 Centromere protein S chr1 GO:0006281 Not Cancer Driver No 6 0.0434782608695652 66 2 0.0144927536231884 0
CEP164-201 CEP164 Q9UPV0 Centrosomal protein of 164 kDa chr11 GO:0006281 Not Cancer Driver No 119 0.0815068493150684 1203 91 0.0623287671232876 2
CGAS-201 CGAS Q8N884 Cyclic GMP-AMP synthase chr6 GO:0006281 Not Cancer Driver No 33 0.0632183908045977 175 6 0.0114942528735632 0
CHAF1A-201 CHAF1A Q13111 Chromatin assembly factor 1 subunit A chr19 GO:0006281 Not Cancer Driver No 66 0.0690376569037656 768 48 0.0502092050209205 0
CHAF1B-201 CHAF1B Q13112 Chromatin assembly factor 1 subunit B chr21 GO:0006281 Not Cancer Driver No 45 0.0805008944543828 189 23 0.0411449016100178 0
CHD1L-202 CHD1L Q86WJ1 Chromodomain-helicase-DNA-binding protein 1-like chr1 GO:0006281 Not Cancer Driver No 75 0.0836120401337792 226 21 0.0234113712374581 0
CHEK1-204 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 GO:0006281 Not Cancer Driver No 42 0.088235294117647 86 13 0.0273109243697479 0
CHRNA4-201 CHRNA4 P43681 Neuronal acetylcholine receptor subunit alpha-4 chr20 GO:0006281 Not Cancer Driver No 112 0.1786283891547049 188 26 0.0414673046251993 1
CINP-201 CINP Q9BW66 Cyclin-dependent kinase 2-interacting protein chr14 GO:0006281 Not Cancer Driver No 15 0.070754716981132 41 3 0.0141509433962264 0
CLSPN-202 CLSPN Q9HAW4 Claspin chr1 GO:0006281 Not Cancer Driver No 92 0.0687079910380881 1287 89 0.0664675130694548 0
CSNK1E-203 CSNK1E P49674 Casein kinase I isoform epsilon chr22 GO:0006281 Not Cancer Driver No 44 0.1057692307692307 133 13 0.03125 0
CUL4A-202 CUL4A Q13619 Cullin-4A chr13 GO:0006281 Not Cancer Driver No 54 0.0711462450592885 102 2 0.0026350461133069 0
DDB1-201 DDB1 Q16531 DNA damage-binding protein 1 chr11 GO:0006281 Not Cancer Driver No 98 0.0859649122807017 50 8 0.0070175438596491 3
DDB2-201 DDB2 Q92466 DNA damage-binding protein 2 chr11 GO:0006281 Census, Compendium Yes 35 0.081967213114754 71 5 0.0117096018735363 2
DDX11-229 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:0006281 Not Cancer Driver No 95 0.0979381443298969 282 32 0.0329896907216494 1
DMAP1-203 DMAP1 Q9NPF5 DNA methyltransferase 1-associated protein 1 chr1 GO:0006281 Not Cancer Driver No 42 0.0899357601713062 270 26 0.0556745182012847 0
DOT1L-201 DOT1L Q8TEK3 Histone-lysine N-methyltransferase, H3 lysine-79 specific chr19 GO:0006281 Compendium Yes 135 0.0878334417696811 990 81 0.0527000650618087 0
DYRK1B-201 DYRK1B Q9Y463 Dual specificity tyrosine-phosphorylation-regulated kinase 1B chr19 GO:0006281 Not Cancer Driver No 67 0.1065182829888712 319 31 0.0492845786963434 2
EEPD1-201 EEPD1 Q7L9B9 Endonuclease/exonuclease/phosphatase family domain-containing protein 1 chr7 GO:0006281 Not Cancer Driver No 62 0.1089630931458699 250 27 0.047451669595782 0
EID3-201 EID3 Q8N140 EP300-interacting inhibitor of differentiation 3 chr12 GO:0006281 Not Cancer Driver No 18 0.054054054054054 56 2 0.006006006006006 0
EMSY-210 EMSY Q7Z589 BRCA2-interacting transcriptional repressor EMSY chr11 GO:0006281 Not Cancer Driver No 127 0.0960665658093797 1149 116 0.0877458396369137 0
ENDOV-204 ENDOV Q8N8Q3 Endonuclease V chr17 GO:0006281 Not Cancer Driver No 20 0.0709219858156028 43 3 0.0106382978723404 0
ENST00000358757 UBE2W Q96B02 Ubiquitin-conjugating enzyme E2 W chr8 GO:0006281 Not Cancer Driver No 12 0.0745341614906832 26 3 0.0186335403726708 0
ENST00000640655 RAD50 Q92878 DNA repair protein RAD50 chr5 GO:0006281 Not Cancer Driver No 92 0.0758450123660346 721 45 0.0370981038746908 0
EP400-204 EP400 Q96L91 E1A-binding protein p400 chr12 GO:0006281 Not Cancer Driver No 244 0.0781300032020493 2031 145 0.0464297150176112 0
EPC2-201 EPC2 Q52LR7 Enhancer of polycomb homolog 2 chr2 GO:0006281 Not Cancer Driver No 72 0.0892193308550185 583 50 0.0619578686493184 0
ERCC1-202 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0006281 Not Cancer Driver No 36 0.1212121212121212 107 14 0.0471380471380471 1
ERCC3-201 ERCC3 P19447 General transcription and DNA repair factor IIH helicase subunit XPB chr2 GO:0006281 Census, Compendium Yes 67 0.0856777493606138 208 14 0.0179028132992327 2
ERCC4-201 ERCC4 Q92889 DNA repair endonuclease XPF chr16 GO:0006281 Census Yes 81 0.0884279475982532 226 19 0.0207423580786026 15
ETAA1-201 ETAA1 Q9NY74 Ewing's tumor-associated antigen 1 chr2 GO:0006281 Not Cancer Driver No 69 0.0745140388768898 742 52 0.0561555075593952 0
EXO1-202 EXO1 Q9UQ84 Exonuclease 1 chr1 GO:0006281 Not Cancer Driver No 92 0.1087470449172576 478 60 0.0709219858156028 0
EXOSC10-202 EXOSC10 Q01780 Exosome component 10 chr1 GO:0006281 Not Cancer Driver No 66 0.0745762711864406 378 27 0.0305084745762711 0
EYA2-202 EYA2 O00167 Eyes absent homolog 2 chr20 GO:0006281 Not Cancer Driver No 89 0.1654275092936803 204 44 0.0817843866171003 0
EYA4-202 EYA4 O95677 Eyes absent homolog 4 chr6 GO:0006281 Not Cancer Driver No 142 0.2222222222222222 339 81 0.1267605633802817 2
FAN1-201 FAN1 Q9Y2M0 Fanconi-associated nuclease 1 chr15 GO:0006281 Not Cancer Driver No 86 0.0845624385447394 212 22 0.0216322517207472 4
FANCA-202 FANCA O15360 Fanconi anemia group A protein chr16 GO:0006281 Census, Compendium Yes 121 0.0831615120274914 157 13 0.00893470790378 26
FANCC-201 FANCC Q00597 Fanconi anemia group C protein chr9 GO:0006281 Census, Compendium Yes 38 0.068100358422939 13 0 0.0 3
FANCG-201 FANCG O15287 Fanconi anemia group G protein chr9 GO:0006281 Census Yes 43 0.0691318327974276 48 1 0.0016077170418006 1
FANCL-201 FANCL Q9NW38 E3 ubiquitin-protein ligase FANCL chr2 GO:0006281 Not Cancer Driver No 39 0.104 11 1 0.0026666666666666 0
FBH1-201 FBH1 Q8NFZ0 F-box DNA helicase 1 chr10 GO:0006281 Not Cancer Driver No 102 0.0977948226270374 192 28 0.0268456375838926 0
FBXO6-201 FBXO6 Q9NRD1 F-box only protein 6 chr1 GO:0006281 Not Cancer Driver No 25 0.0853242320819112 27 3 0.0102389078498293 0
FBXW7-201 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:0006281 Census, Compendium Yes 289 0.4087694483734088 232 15 0.0212164073550212 17
FEN1-201 FEN1 P39748 Flap endonuclease 1 chr11 GO:0006281 Census Yes 29 0.0763157894736842 111 13 0.0342105263157894 0
FH-201 FH P07954 Fumarate hydratase, mitochondrial chr1 GO:0006281 Census, Compendium Yes 54 0.1058823529411764 76 4 0.0078431372549019 13
FMR1-205 FMR1 Q06787 Fragile X messenger ribonucleoprotein 1 chrX GO:0006281 Not Cancer Driver No 92 0.1455696202531645 327 50 0.0791139240506329 3
FOXM1-202 FOXM1 Q08050 Forkhead box protein M1 chr12 GO:0006281 Not Cancer Driver No 73 0.0956749672346002 605 57 0.0747051114023591 0
FZR1-202 FZR1 Q9UM11 Fizzy-related protein homolog chr19 GO:0006281 Not Cancer Driver No 64 0.1290322580645161 184 24 0.0483870967741935 2
GADD45A-202 GADD45A P24522 Growth arrest and DNA damage-inducible protein GADD45 alpha chr1 GO:0006281 Not Cancer Driver No 8 0.0484848484848484 40 4 0.0242424242424242 0
GTF2H1-201 GTF2H1 P32780 General transcription factor IIH subunit 1 chr11 GO:0006281 Not Cancer Driver No 36 0.0656934306569343 139 9 0.0164233576642335 0
GTF2H3-212 GTF2H3 Q13889 General transcription factor IIH subunit 3 chr12 GO:0006281 Not Cancer Driver No 22 0.0714285714285714 20 1 0.0032467532467532 0
GTF2H4-201 GTF2H4 Q92759 General transcription factor IIH subunit 4 chr6 GO:0006281 Not Cancer Driver No 33 0.0714285714285714 30 4 0.0086580086580086 0
HDAC10-201 HDAC10 Q969S8 Polyamine deacetylase HDAC10 chr22 GO:0006281 Not Cancer Driver No 53 0.0792227204783258 122 11 0.0164424514200298 0
HDGFL2-208 HDGFL2 Q7Z4V5 Hepatoma-derived growth factor-related protein 2 chr19 GO:0006281 Not Cancer Driver No 26 0.0387481371087928 622 26 0.0387481371087928 0
HELB-201 HELB Q8NG08 DNA helicase B chr12 GO:0006281 Not Cancer Driver No 96 0.0883164673413063 302 24 0.0220791168353265 0
HERC2-201 HERC2 O95714 E3 ubiquitin-protein ligase HERC2 chr15 GO:0006281 Compendium Yes 517 0.1069507654116673 971 113 0.0233760860570955 1
HINFP-201 HINFP Q9BQA5 Histone H4 transcription factor chr11 GO:0006281 Not Cancer Driver No 49 0.0947775628626692 156 20 0.0386847195357833 0
HLTF-201 HLTF Q14527 Helicase-like transcription factor chr3 GO:0006281 Not Cancer Driver No 80 0.0792864222001982 360 27 0.0267591674925668 0
HPF1-201 HPF1 Q9NWY4 Histone PARylation factor 1 chr4 GO:0006281 Not Cancer Driver No 19 0.0549132947976878 23 0 0.0 0
HSF1-204 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0006281 Not Cancer Driver No 49 0.0926275992438563 336 30 0.0567107750472589 0
HUS1-201 HUS1 O60921 Checkpoint protein HUS1 chr7 GO:0006281 Not Cancer Driver No 19 0.0678571428571428 17 1 0.0035714285714285 0
INIP-203 INIP Q9NRY2 SOSS complex subunit C chr9 GO:0006281 Not Cancer Driver No 14 0.1346153846153846 79 9 0.0865384615384615 0
INO80-209 INO80 Q9ULG1 Chromatin-remodeling ATPase INO80 chr15 GO:0006281 Compendium Yes 137 0.0880462724935732 682 67 0.0430591259640102 0
INO80B-201 INO80B Q9C086 INO80 complex subunit B chr2 GO:0006281 Not Cancer Driver No 24 0.0674157303370786 336 22 0.0617977528089887 0
INO80B-WBP1-202 INO80B Q9C086 INO80 complex subunit B chr2 GO:0006281 Not Cancer Driver No 27 0.0743801652892562 337 25 0.0688705234159779 0
INO80C-202 INO80C Q6PI98 INO80 complex subunit C chr18 GO:0006281 Not Cancer Driver No 17 0.0885416666666666 109 11 0.0572916666666666 0
INO80D-201 INO80D Q53TQ3 INO80 complex subunit D chr2 GO:0006281 Not Cancer Driver No 84 0.0817916260954235 738 68 0.0662122687439143 0
INO80E-207 INO80E Q8NBZ0 INO80 complex subunit E chr16 GO:0006281 Not Cancer Driver No 15 0.0614754098360655 211 15 0.0614754098360655 0
INTS3-201 INTS3 Q68E01 Integrator complex subunit 3 chr1 GO:0006281 Not Cancer Driver No 91 0.0873320537428023 213 19 0.0182341650671785 0
JMY-201 JMY Q8N9B5 Junction-mediating and -regulatory protein chr5 GO:0006281 Not Cancer Driver No 58 0.0587044534412955 576 37 0.0374493927125506 0
KAT7-201 KAT7 O95251 Histone acetyltransferase KAT7 chr17 GO:0006281 Census Yes 64 0.1047463175122749 327 27 0.044189852700491 0
KIF22-201 KIF22 Q14807 Kinesin-like protein KIF22 chr16 GO:0006281 Not Cancer Driver No 63 0.0947368421052631 324 31 0.0466165413533834 2
KIN-201 KIN O60870 DNA/RNA-binding protein KIN17 chr10 GO:0006281 Not Cancer Driver No 36 0.0916030534351145 137 10 0.0254452926208651 0
KMT5B-201 KMT5B Q4FZB7 Histone-lysine N-methyltransferase KMT5B chr11 GO:0006281 Not Cancer Driver No 111 0.1254237288135593 660 85 0.096045197740113 0
KMT5C-201 KMT5C Q86Y97 Histone-lysine N-methyltransferase KMT5C chr19 GO:0006281 Not Cancer Driver No 31 0.0670995670995671 142 9 0.0194805194805194 0
LIG1-201 LIG1 P18858 DNA ligase 1 chr19 GO:0006281 Not Cancer Driver No 99 0.1077257889009793 400 50 0.0544069640914037 3
MACROH2A1-202 MACROH2A1 O75367 Core histone macro-H2A.1 chr5 GO:0006281 Not Cancer Driver No 31 0.084010840108401 122 9 0.024390243902439 0
MBD4-201 MBD4 O95243 Methyl-CpG-binding domain protein 4 chr3 GO:0006281 Not Cancer Driver No 34 0.0586206896551724 268 11 0.0189655172413793 1
MCRS1-201 MCRS1 Q96EZ8 Microspherule protein 1 chr12 GO:0006281 Not Cancer Driver No 47 0.1017316017316017 152 13 0.0281385281385281 0
MDC1-201 MDC1 Q14676 Mediator of DNA damage checkpoint protein 1 chr6 GO:0006281 Not Cancer Driver No 175 0.0837721397797989 1829 156 0.0746768788894207 0
MEN1-203 MEN1 O00255 Menin chr11 GO:0006281 Census, Compendium Yes 50 0.08130081300813 230 9 0.0146341463414634 80
MGMT-205 MGMT P16455 Methylated-DNA--protein-cysteine methyltransferase chr10 GO:0006281 Census Yes 23 0.1111111111111111 39 4 0.0193236714975845 0
MMS19-209 MMS19 Q96T76 MMS19 nucleotide excision repair protein homolog chr10 GO:0006281 Not Cancer Driver No 54 0.0524271844660194 11 0 0.0 0
MNAT1-201 MNAT1 P51948 CDK-activating kinase assembly factor MAT1 chr14 GO:0006281 Not Cancer Driver No 20 0.0647249190938511 64 2 0.0064724919093851 0
MORF4L2-206 MORF4L2 Q15014 Mortality factor 4-like protein 2 chrX GO:0006281 Not Cancer Driver No 30 0.1041666666666666 136 17 0.0590277777777777 0
MRE11-201 MRE11 P49959 Double-strand break repair protein MRE11 chr11 GO:0006281 Not Cancer Driver No 61 0.0861581920903954 292 28 0.03954802259887 1
MRNIP-201 MRNIP Q6NTE8 MRN complex-interacting protein chr5 GO:0006281 Not Cancer Driver No 27 0.0787172011661807 269 24 0.0699708454810495 0
MSH2-201 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0006281 Census Yes 55 0.0588865096359743 37 1 0.0010706638115631 63
MSH3-201 MSH3 P20585 DNA mismatch repair protein Msh3 chr5 GO:0006281 Not Cancer Driver No 65 0.0571679859278803 218 11 0.0096745822339489 0
MSH6-201 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 GO:0006281 Census Yes 92 0.0676470588235294 389 26 0.0191176470588235 6
MUS81-201 MUS81 Q96NY9 Crossover junction endonuclease MUS81 chr11 GO:0006281 Not Cancer Driver No 47 0.0852994555353902 235 25 0.0453720508166969 0
MUTYH-245 MUTYH Q9UIF7 Adenine DNA glycosylase chr1 GO:0006281 Census Yes 71 0.13003663003663 198 21 0.0384615384615384 23
NABP1-205 NABP1 Q96AH0 SOSS complex subunit B2 chr2 GO:0006281 Not Cancer Driver No 20 0.0980392156862745 102 8 0.0392156862745098 0
NABP2-201 NABP2 Q9BQ15 SOSS complex subunit B1 chr12 GO:0006281 Not Cancer Driver No 22 0.1042654028436018 125 14 0.0663507109004739 0
NFRKB-212 NFRKB Q6P4R8 Nuclear factor related to kappa-B-binding protein chr11 GO:0006281 Not Cancer Driver No 54 0.0415704387990762 838 24 0.0184757505773672 0
NME3-201 NME3 Q13232 Nucleoside diphosphate kinase 3 chr16 GO:0006281 Not Cancer Driver No 8 0.0473372781065088 4 0 0.0 0
NONO-201 NONO Q15233 Non-POU domain-containing octamer-binding protein chrX GO:0006281 Census, Compendium Yes 70 0.1486199575371549 349 46 0.0976645435244161 0
NOP53-201 NOP53 Q9NZM5 Ribosome biogenesis protein NOP53 chr19 GO:0006281 Not Cancer Driver No 36 0.0753138075313807 399 26 0.0543933054393305 0
NPM1-201 NPM1 P06748 Nucleophosmin chr5 GO:0006281 Census, Compendium Yes 25 0.0850340136054421 249 19 0.064625850340136 0
NSMCE3-201 NSMCE3 Q96MG7 Non-structural maintenance of chromosomes element 3 homolog chr15 GO:0006281 Not Cancer Driver No 24 0.0789473684210526 129 6 0.0197368421052631 2
NSMCE4A-202 NSMCE4A Q9NXX6 Non-structural maintenance of chromosomes element 4 homolog A chr10 GO:0006281 Not Cancer Driver No 10 0.0259740259740259 201 2 0.0051948051948051 0
NUDT1-203 NUDT1 P36639 Oxidized purine nucleoside triphosphate hydrolase chr7 GO:0006281 Not Cancer Driver No 23 0.1474358974358974 17 4 0.0256410256410256 0
NYNRIN-201 NYNRIN Q9P2P1 Protein NYNRIN chr14 GO:0006281 Not Cancer Driver No 202 0.1064278187565858 640 60 0.0316122233930453 0
OTUB1-208 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 GO:0006281 Not Cancer Driver No 25 0.092250922509225 34 3 0.011070110701107 0
PAGR1-201 PAGR1 Q9BTK6 PAXIP1-associated glutamate-rich protein 1 chr16 GO:0006281 Not Cancer Driver No 17 0.0669291338582677 254 17 0.0669291338582677 0
PARK7-201 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0006281 Not Cancer Driver No 8 0.0423280423280423 30 0 0.0 6
PARP1-203 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0006281 Not Cancer Driver No 88 0.0867850098619329 322 28 0.0276134122287968 0
PARP2-201 PARP2 Q9UGN5 Poly [ADP-ribose] polymerase 2 chr14 GO:0006281 Not Cancer Driver No 44 0.0754716981132075 172 16 0.0274442538593482 0
PARP4-201 PARP4 Q9UKK3 Protein mono-ADP-ribosyltransferase PARP4 chr13 GO:0006281 Compendium Yes 153 0.0887470997679814 327 28 0.0162412993039443 0
PARPBP-201 PARPBP Q9NWS1 PCNA-interacting partner chr12 GO:0006281 Not Cancer Driver No 48 0.082901554404145 173 16 0.0276338514680483 0
PAXIP1-201 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 GO:0006281 Not Cancer Driver No 41 0.0383536014967259 462 1 0.000935453695042 0
PDS5A-201 PDS5A Q29RF7 Sister chromatid cohesion protein PDS5 homolog A chr4 GO:0006281 Not Cancer Driver No 101 0.075542258788332 295 28 0.0209424083769633 0
PDS5B-201 PDS5B Q9NTI5 Sister chromatid cohesion protein PDS5 homolog B chr13 GO:0006281 Not Cancer Driver No 127 0.0877677954388389 455 45 0.0310988251554941 0
PIF1-205 PIF1 Q9H611 ATP-dependent DNA helicase PIF1 chr15 GO:0006281 Not Cancer Driver No 44 0.0686427457098284 210 9 0.0140405616224648 0
PNKP-201 PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 GO:0006281 Not Cancer Driver No 46 0.0882917466410748 177 21 0.0403071017274472 4
POLA1-201 POLA1 P09884 DNA polymerase alpha catalytic subunit chrX GO:0006281 Not Cancer Driver No 113 0.0772913816689466 347 30 0.0205198358413132 3
POLB-201 POLB P06746 DNA polymerase beta chr8 GO:0006281 Not Cancer Driver No 32 0.0955223880597015 87 8 0.0238805970149253 0
POLD1-201 POLD1 P28340 DNA polymerase delta catalytic subunit chr19 GO:0006281 Census, Compendium Yes 118 0.1065943992773261 210 17 0.015356820234869 2
POLE2-201 POLE2 P56282 DNA polymerase epsilon subunit 2 chr14 GO:0006281 Not Cancer Driver No 37 0.0702087286527514 32 1 0.0018975332068311 0
POLH-202 POLH Q9Y253 DNA polymerase eta chr6 GO:0006281 Not Cancer Driver No 49 0.0687237026647966 291 15 0.0210378681626928 10
POLI-208 POLI Q9UNA4 DNA polymerase iota chr18 GO:0006281 Not Cancer Driver No 50 0.0675675675675675 302 20 0.027027027027027 0
POLK-201 POLK Q9UBT6 DNA polymerase kappa chr5 GO:0006281 Not Cancer Driver No 66 0.0758620689655172 294 25 0.028735632183908 0
POLQ-201 POLQ O75417 DNA polymerase theta chr3 GO:0006281 Census, Compendium Yes 274 0.1057915057915057 956 94 0.0362934362934362 0
PSME4-202 PSME4 Q14997 Proteasome activator complex subunit 4 chr2 GO:0006281 Not Cancer Driver No 156 0.0846446011937059 134 11 0.005968529571351 0
PTTG1-201 PTTG1 O95997 Securin chr5 GO:0006281 Not Cancer Driver No 10 0.0495049504950495 141 4 0.0198019801980198 0
PWWP3A-210 PWWP3A Q2TAK8 PWWP domain-containing DNA repair factor 3A chr19 GO:0006281 Not Cancer Driver No 56 0.0788732394366197 353 30 0.0422535211267605 0
RAD1-203 RAD1 O60671 Cell cycle checkpoint protein RAD1 chr5 GO:0006281 Not Cancer Driver No 19 0.0673758865248227 4 0 0.0 0
RAD17-208 RAD17 O75943 Cell cycle checkpoint protein RAD17 chr5 GO:0006281 Census Yes 53 0.0778267254038179 207 12 0.0176211453744493 0
RAD18-201 RAD18 Q9NS91 E3 ubiquitin-protein ligase RAD18 chr3 GO:0006281 Not Cancer Driver No 42 0.0848484848484848 330 31 0.0626262626262626 0
RAD50-201 RAD50 Q92878 DNA repair protein RAD50 chr5 GO:0006281 Not Cancer Driver No 106 0.0807926829268292 730 50 0.0381097560975609 0
RAD51-201 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 GO:0006281 Not Cancer Driver No 27 0.079646017699115 48 3 0.0088495575221238 3
RAD51AP1-201 RAD51AP1 Q96B01 RAD51-associated protein 1 chr12 GO:0006281 Not Cancer Driver No 37 0.1051136363636363 337 35 0.0994318181818181 0
RAD51B-209 RAD51B O15315 DNA repair protein RAD51 homolog 2 chr14 GO:0006281 Census Yes 32 0.0833333333333333 12 0 0.0 0
RAD51C-201 RAD51C O43502 DNA repair protein RAD51 homolog 3 chr17 GO:0006281 Not Cancer Driver No 39 0.1037234042553191 18 2 0.0053191489361702 6
RAD51D-202 RAD51D O75771 DNA repair protein RAD51 homolog 4 chr17 GO:0006281 Not Cancer Driver No 20 0.0609756097560975 50 8 0.024390243902439 0
RAD54L-201 RAD54L Q92698 DNA repair and recombination protein RAD54-like chr1 GO:0006281 Not Cancer Driver No 62 0.0829986613119143 125 11 0.0147255689424364 0
RAD9A-201 RAD9A Q99638 Cell cycle checkpoint control protein RAD9A chr11 GO:0006281 Not Cancer Driver No 32 0.0818414322250639 136 7 0.0179028132992327 0
RAD9B-204 RAD9B Q6WBX8 Cell cycle checkpoint control protein RAD9B chr12 GO:0006281 Not Cancer Driver No 32 0.0767386091127098 57 4 0.0095923261390887 0
RBBP8-201 RBBP8 Q99708 DNA endonuclease RBBP8 chr18 GO:0006281 Not Cancer Driver No 72 0.0802675585284281 751 54 0.060200668896321 1
RBX1-201 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 GO:0006281 Not Cancer Driver No 9 0.0833333333333333 18 1 0.0092592592592592 0
RECQL-204 RECQL P46063 ATP-dependent DNA helicase Q1 chr12 GO:0006281 Not Cancer Driver No 50 0.0770416024653312 91 1 0.0015408320493066 0
RECQL4-209 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 GO:0006281 Census, Compendium Yes 105 0.0869205298013245 612 54 0.0447019867549668 1
RECQL5-201 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 GO:0006281 Not Cancer Driver No 101 0.1019172552976791 499 57 0.0575176589303733 0
REXO4-202 REXO4 Q9GZR2 RNA exonuclease 4 chr9 GO:0006281 Not Cancer Driver No 24 0.0568720379146919 298 17 0.0402843601895734 0
RFC1-202 RFC1 P35251 Replication factor C subunit 1 chr4 GO:0006281 Not Cancer Driver No 80 0.0696864111498257 676 42 0.0365853658536585 0
RFC2-201 RFC2 P35250 Replication factor C subunit 2 chr7 GO:0006281 Not Cancer Driver No 41 0.115819209039548 39 5 0.0141242937853107 0
RFC3-201 RFC3 P40938 Replication factor C subunit 3 chr13 GO:0006281 Not Cancer Driver No 22 0.0617977528089887 13 1 0.0028089887640449 0
RFC4-201 RFC4 P35249 Replication factor C subunit 4 chr3 GO:0006281 Not Cancer Driver No 41 0.1129476584022038 50 1 0.0027548209366391 0
RFC5-204 RFC5 P40937 Replication factor C subunit 5 chr12 GO:0006281 Not Cancer Driver No 26 0.0764705882352941 20 2 0.0058823529411764 0
RIF1-205 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 GO:0006281 Not Cancer Driver No 194 0.0784789644012945 1364 112 0.0453074433656957 0
RMI2-201 RMI2 Q96E14 RecQ-mediated genome instability protein 2 chr16 GO:0006281 Census Yes 6 0.0408163265306122 88 3 0.0204081632653061 0
RNF113A-201 RNF113A O15541 E3 ubiquitin-protein ligase RNF113A chrX GO:0006281 Not Cancer Driver No 48 0.1399416909620991 227 44 0.1282798833819242 0
RPA1-201 RPA1 P27694 Replication protein A 70 kDa DNA-binding subunit chr17 GO:0006281 Not Cancer Driver No 45 0.073051948051948 98 7 0.0113636363636363 1
RPA3-201 RPA3 P35244 Replication protein A 14 kDa subunit chr7 GO:0006281 Not Cancer Driver No 10 0.0826446280991735 4 1 0.0082644628099173 0
RPA4-201 RPA4 Q13156 Replication protein A 30 kDa subunit chrX GO:0006281 Not Cancer Driver No 56 0.21455938697318 59 10 0.0383141762452107 0
RPS3-217 RPS3 P23396 Small ribosomal subunit protein uS3 chr11 GO:0006281 Not Cancer Driver No 22 0.0905349794238683 48 4 0.0164609053497942 0
RRM1-201 RRM1 P23921 Ribonucleoside-diphosphate reductase large subunit chr11 GO:0006281 Not Cancer Driver No 54 0.0681818181818181 41 5 0.0063131313131313 0
RRM2B-201 RRM2B Q7LG56 Ribonucleoside-diphosphate reductase subunit M2 B chr8 GO:0006281 Not Cancer Driver No 31 0.0883190883190883 32 4 0.0113960113960113 9
RTEL1-205 RTEL1 Q9NZ71 Regulator of telomere elongation helicase 1 chr20 GO:0006281 Not Cancer Driver No 106 0.0869565217391304 479 50 0.0410172272354388 15
RUVBL1-201 RUVBL1 Q9Y265 RuvB-like 1 chr3 GO:0006281 Not Cancer Driver No 41 0.0899122807017543 67 5 0.0109649122807017 0
RUVBL2-206 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0006281 Not Cancer Driver No 52 0.1123110151187904 100 11 0.0237580993520518 0
SHLD1-201 SHLD1 Q8IYI0 Shieldin complex subunit 1 chr20 GO:0006281 Not Cancer Driver No 25 0.1219512195121951 118 18 0.0878048780487804 0
SHLD2-201 SHLD2 Q86V20 Shieldin complex subunit 2 chr10 GO:0006281 Not Cancer Driver No 51 0.0610778443113772 156 5 0.0059880239520958 0
SHLD3-201 SHLD3 Q6ZNX1 Shieldin complex subunit 3 chr5 GO:0006281 Not Cancer Driver No 2 0.008 82 1 0.004 0
SHPRH-201 SHPRH Q149N8 E3 ubiquitin-protein ligase SHPRH chr6 GO:0006281 Not Cancer Driver No 173 0.1027926322043969 362 45 0.0267379679144385 0
SIRT7-201 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 GO:0006281 Not Cancer Driver No 34 0.085 163 10 0.025 0
SLX1A-201 SLX1B Q9BQ83 Structure-specific endonuclease subunit SLX1 chr16 GO:0006281 Not Cancer Driver No 3 0.0109090909090909 80 0 0.0 0
SLX1B-201 SLX1B Q9BQ83 Structure-specific endonuclease subunit SLX1 chr16 GO:0006281 Not Cancer Driver No 3 0.0109090909090909 80 0 0.0 0
SLX4-201 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 GO:0006281 Not Cancer Driver No 201 0.1095965103598691 1586 175 0.0954198473282442 0
SMARCA5-201 SMARCA5 O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 chr4 GO:0006281 Not Cancer Driver No 73 0.0693916349809885 364 26 0.0247148288973384 0
SMARCAL1-201 SMARCAL1 Q9NZC9 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 chr2 GO:0006281 Not Cancer Driver No 98 0.1027253668763102 340 37 0.0387840670859538 10
SMC1A-201 SMC1A Q14683 Structural maintenance of chromosomes protein 1A chrX GO:0006281 Census, Compendium Yes 142 0.1151662611516626 717 83 0.0673154906731549 17
SMC3-201 SMC3 Q9UQE7 Structural maintenance of chromosomes protein 3 chr10 GO:0006281 Not Cancer Driver No 116 0.09531635168447 605 49 0.0402629416598192 0
SMG1-201 SMG1 Q96Q15 Serine/threonine-protein kinase SMG1 chr16 GO:0006281 Not Cancer Driver No 237 0.0647364108167167 607 45 0.0122917235727943 0
SSRP1-201 SSRP1 Q08945 FACT complex subunit SSRP1 chr11 GO:0006281 Not Cancer Driver No 66 0.0930888575458392 308 22 0.0310296191819464 0
STUB1-201 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:0006281 Not Cancer Driver No 29 0.0957095709570957 113 11 0.0363036303630363 11
SUMO1-203 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 GO:0006281 Not Cancer Driver No 10 0.099009900990099 76 7 0.0693069306930693 0
SUPT16H-201 SUPT16H Q9Y5B9 FACT complex subunit SPT16 chr14 GO:0006281 Not Cancer Driver No 109 0.1041069723018147 303 34 0.0324737344794651 0
TAOK1-201 TAOK1 Q7L7X3 Serine/threonine-protein kinase TAO1 chr17 GO:0006281 Not Cancer Driver No 94 0.0939060939060939 602 48 0.0479520479520479 7
TAOK3-201 TAOK3 Q9H2K8 Serine/threonine-protein kinase TAO3 chr12 GO:0006281 Not Cancer Driver No 95 0.1057906458797327 494 51 0.0567928730512249 0
TDP1-201 TDP1 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 chr14 GO:0006281 Not Cancer Driver No 64 0.1052631578947368 179 20 0.0328947368421052 1
TEX15-201 TEX15 Q9BXT5 Testis-expressed protein 15 chr8 GO:0006281 Not Cancer Driver No 326 0.1168877733954822 1256 151 0.0541412692721405 0
TFPT-203 TFPT P0C1Z6 TCF3 fusion partner chr19 GO:0006281 Census Yes 32 0.1264822134387351 237 31 0.1225296442687747 0
TICRR-201 TICRR Q7Z2Z1 Treslin chr15 GO:0006281 Not Cancer Driver No 152 0.0795811518324607 1314 100 0.0523560209424083 0
TIMELESS-203 TIMELESS Q9UNS1 Protein timeless homolog chr12 GO:0006281 Not Cancer Driver No 127 0.1051324503311258 371 44 0.0364238410596026 0
TOP3A-201 TOP3A Q13472 DNA topoisomerase 3-alpha chr17 GO:0006281 Not Cancer Driver No 79 0.0789210789210789 293 28 0.0279720279720279 2
TOP3B-201 TOP3B O95985 DNA topoisomerase 3-beta-1 chr22 GO:0006281 Not Cancer Driver No 76 0.0881670533642691 151 11 0.0127610208816705 0
TOPBP1-201 TOPBP1 Q92547 DNA topoisomerase 2-binding protein 1 chr3 GO:0006281 Not Cancer Driver No 121 0.0795006570302234 579 43 0.0282522996057818 0
TPTEP2-CSNK1E-201 CSNK1E P49674 Casein kinase I isoform epsilon chr22 GO:0006281 Not Cancer Driver No 44 0.1057692307692307 133 13 0.03125 0
TREX1-205 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0006281 Not Cancer Driver No 24 0.0764331210191082 98 7 0.0222929936305732 17
TREX2-205 TREX2 Q9BQ50 Three prime repair exonuclease 2 chrX GO:0006281 Not Cancer Driver No 27 0.1144067796610169 23 5 0.0211864406779661 0
TRIM28-201 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 GO:0006281 Not Cancer Driver No 67 0.0802395209580838 431 32 0.0383233532934131 0
TRIP12-201 TRIP12 Q14669 E3 ubiquitin-protein ligase TRIP12 chr2 GO:0006281 Not Cancer Driver No 154 0.0773092369477911 847 82 0.0411646586345381 4
TRRAP-202 TRRAP Q9Y4A5 Transformation/transcription domain-associated protein chr7 GO:0006281 Census, Compendium Yes 431 0.1116869655351127 402 47 0.0121793210676341 8
TTC5-201 TTC5 Q8N0Z6 Tetratricopeptide repeat protein 5 chr14 GO:0006281 Not Cancer Driver No 46 0.1045454545454545 154 13 0.0295454545454545 0
TTF2-201 TTF2 Q9UNY4 Transcription termination factor 2 chr1 GO:0006281 Not Cancer Driver No 86 0.0740103270223752 554 43 0.0370051635111876 0
UBE2A-202 UBE2A P49459 Ubiquitin-conjugating enzyme E2 A chrX GO:0006281 Compendium Yes 23 0.1513157894736842 67 11 0.0723684210526315 2
UBE2B-201 UBE2B P63146 Ubiquitin-conjugating enzyme E2 B chr5 GO:0006281 Not Cancer Driver No 9 0.0592105263157894 68 4 0.0263157894736842 0
UBE2D3-210 UBE2D3 P61077 Ubiquitin-conjugating enzyme E2 D3 chr4 GO:0006281 Not Cancer Driver No 15 0.1020408163265306 13 3 0.0204081632653061 0
UBE2T-205 UBE2T Q9NPD8 Ubiquitin-conjugating enzyme E2 T chr1 GO:0006281 Not Cancer Driver No 11 0.0558375634517766 97 8 0.0406091370558375 1
UBE2W-207 UBE2W Q96B02 Ubiquitin-conjugating enzyme E2 W chr8 GO:0006281 Not Cancer Driver No 12 0.0794701986754966 26 3 0.0198675496688741 0
UBQLN4-201 UBQLN4 Q9NRR5 Ubiquilin-4 chr1 GO:0006281 Not Cancer Driver No 37 0.0615640599001663 563 35 0.0582362728785357 1
UBR5-207 UBR5 O95071 E3 ubiquitin-protein ligase UBR5 chr8 GO:0006281 Census, Compendium Yes 260 0.0928903179707038 1299 135 0.0482315112540192 0
UCHL5-206 UCHL5 Q9Y5K5 Ubiquitin carboxyl-terminal hydrolase isozyme L5 chr1 GO:0006281 Not Cancer Driver No 23 0.0699088145896656 41 2 0.0060790273556231 0
UFL1-201 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 GO:0006281 Not Cancer Driver No 77 0.096977329974811 141 19 0.0239294710327455 0
UPF1-207 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 GO:0006281 Not Cancer Driver No 114 0.1009743135518157 330 33 0.0292294065544729 0
USP1-201 USP1 O94782 Ubiquitin carboxyl-terminal hydrolase 1 chr1 GO:0006281 Not Cancer Driver No 45 0.0573248407643312 405 20 0.0254777070063694 0
USP28-201 USP28 Q96RU2 Ubiquitin carboxyl-terminal hydrolase 28 chr11 GO:0006281 Not Cancer Driver No 106 0.0984215413184772 311 18 0.0167130919220055 0
USP3-202 USP3 Q9Y6I4 Ubiquitin carboxyl-terminal hydrolase 3 chr15 GO:0006281 Not Cancer Driver No 48 0.0923076923076923 45 3 0.0057692307692307 0
USP45-208 USP45 Q70EL2 Ubiquitin carboxyl-terminal hydrolase 45 chr6 GO:0006281 Not Cancer Driver No 60 0.0737100737100737 277 20 0.0245700245700245 0
USP51-201 USP51 Q70EK9 Ubiquitin carboxyl-terminal hydrolase 51 chrX GO:0006281 Not Cancer Driver No 78 0.1097046413502109 246 30 0.0421940928270042 0
UVRAG-201 UVRAG Q9P2Y5 UV radiation resistance-associated gene protein chr11 GO:0006281 Not Cancer Driver No 58 0.0829756795422031 243 21 0.0300429184549356 0
VCP-201 VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0006281 Not Cancer Driver No 74 0.0918114143920595 186 14 0.0173697270471464 12
WDHD1-201 WDHD1 O75717 WD repeat and HMG-box DNA-binding protein 1 chr14 GO:0006281 Not Cancer Driver No 62 0.0549158547387068 476 18 0.0159433126660761 0
WRAP53-202 WRAP53 Q9BUR4 Telomerase Cajal body protein 1 chr17 GO:0006281 Not Cancer Driver No 46 0.083941605839416 234 21 0.0383211678832116 4
XPA-201 XPA P23025 DNA repair protein complementing XP-A cells chr9 GO:0006281 Census Yes 12 0.0439560439560439 121 6 0.0219780219780219 5
XPC-201 XPC Q01831 DNA repair protein complementing XP-C cells chr3 GO:0006281 Census, Compendium Yes 64 0.0680851063829787 484 34 0.0361702127659574 2
XRCC2-201 XRCC2 O43543 DNA repair protein XRCC2 chr7 GO:0006281 Not Cancer Driver No 27 0.0964285714285714 9 0 0.0 2
XRCC3-211 XRCC3 O43542 DNA repair protein XRCC3 chr14 GO:0006281 Not Cancer Driver No 21 0.0606936416184971 35 2 0.0057803468208092 1
ZBTB1-207 ZBTB1 Q9Y2K1 Zinc finger and BTB domain-containing protein 1 chr14 GO:0006281 Not Cancer Driver No 50 0.0701262272089761 273 17 0.0238429172510518 0
ZMPSTE24-201 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0006281 Not Cancer Driver No 46 0.0968421052631579 23 0 0.0 3
ZNF668-201 ZNF668 Q96K58 Zinc finger protein 668 chr16 GO:0006281 Not Cancer Driver No 71 0.1147011308562197 313 35 0.0565428109854604 0
ZRANB3-201 ZRANB3 Q5FWF4 DNA annealing helicase and endonuclease ZRANB3 chr2 GO:0006281 Not Cancer Driver No 100 0.0926784059314179 264 29 0.0268767377201112 0