Total number of protein in "GO:0006284" GO term: 29
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| APEX1-201 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | GO:0006284 | Not Cancer Driver | No | 23 | 0.0723270440251572 | 104 | 9 | 0.0283018867924528 | 0 |
| APEX2-201 | APEX2 | Q9UBZ4 | DNA-(apurinic or apyrimidinic site) endonuclease 2 | chrX | GO:0006284 | Not Cancer Driver | No | 56 | 0.1081081081081081 | 149 | 13 | 0.025096525096525 | 0 |
| DNA2-201 | DNA2 | P51530 | DNA replication ATP-dependent helicase/nuclease DNA2 | chr10 | GO:0006284 | Not Cancer Driver | No | 72 | 0.0679245283018867 | 52 | 4 | 0.0037735849056603 | 3 |
| ERCC6-201 | ERCC6 | Q03468 | DNA excision repair protein ERCC-6 | chr10 | GO:0006284 | Not Cancer Driver | No | 142 | 0.0951105157401205 | 837 | 82 | 0.0549229738780977 | 9 |
| HMGA2-204 | HMGA2 | P52926 | High mobility group protein HMGI-C | chr12 | GO:0006284 | Census | Yes | 9 | 0.0825688073394495 | 109 | 9 | 0.0825688073394495 | 0 |
| HUWE1-202 | HUWE1 | Q7Z6Z7 | E3 ubiquitin-protein ligase HUWE1 | chrX | GO:0006284 | Not Cancer Driver | No | 263 | 0.0601280292638317 | 2091 | 107 | 0.0244627343392775 | 20 |
| LIG1-201 | LIG1 | P18858 | DNA ligase 1 | chr19 | GO:0006284 | Not Cancer Driver | No | 99 | 0.1077257889009793 | 400 | 50 | 0.0544069640914037 | 3 |
| MPG-201 | MPG | P29372 | DNA-3-methyladenine glycosylase | chr16 | GO:0006284 | Not Cancer Driver | No | 31 | 0.1040268456375839 | 143 | 18 | 0.0604026845637583 | 0 |
| MUTYH-245 | MUTYH | Q9UIF7 | Adenine DNA glycosylase | chr1 | GO:0006284 | Census | Yes | 71 | 0.13003663003663 | 198 | 21 | 0.0384615384615384 | 23 |
| NEIL1-201 | NEIL1 | Q96FI4 | Endonuclease 8-like 1 | chr15 | GO:0006284 | Not Cancer Driver | No | 32 | 0.082051282051282 | 166 | 10 | 0.0256410256410256 | 0 |
| NEIL2-201 | NEIL2 | Q969S2 | Endonuclease 8-like 2 | chr8 | GO:0006284 | Not Cancer Driver | No | 26 | 0.0783132530120482 | 145 | 13 | 0.0391566265060241 | 0 |
| NEIL3-201 | NEIL3 | Q8TAT5 | Endonuclease 8-like 3 | chr4 | GO:0006284 | Not Cancer Driver | No | 53 | 0.0876033057851239 | 136 | 9 | 0.0148760330578512 | 0 |
| OGG1-205 | OGG1 | O15527 | N-glycosylase/DNA lyase | chr3 | GO:0006284 | Not Cancer Driver | No | 26 | 0.0753623188405797 | 72 | 4 | 0.0115942028985507 | 0 |
| PARP2-201 | PARP2 | Q9UGN5 | Poly [ADP-ribose] polymerase 2 | chr14 | GO:0006284 | Not Cancer Driver | No | 44 | 0.0754716981132075 | 172 | 16 | 0.0274442538593482 | 0 |
| POLB-201 | POLB | P06746 | DNA polymerase beta | chr8 | GO:0006284 | Not Cancer Driver | No | 32 | 0.0955223880597015 | 87 | 8 | 0.0238805970149253 | 0 |
| POLQ-201 | POLQ | O75417 | DNA polymerase theta | chr3 | GO:0006284 | Census, Compendium | Yes | 274 | 0.1057915057915057 | 956 | 94 | 0.0362934362934362 | 0 |
| PRMT6-201 | PRMT6 | Q96LA8 | Protein arginine N-methyltransferase 6 | chr1 | GO:0006284 | Not Cancer Driver | No | 35 | 0.0933333333333333 | 71 | 5 | 0.0133333333333333 | 0 |
| RPA1-201 | RPA1 | P27694 | Replication protein A 70 kDa DNA-binding subunit | chr17 | GO:0006284 | Not Cancer Driver | No | 45 | 0.073051948051948 | 98 | 7 | 0.0113636363636363 | 1 |
| RPA2-203 | RPA2 | P15927 | Replication protein A 32 kDa subunit | chr1 | GO:0006284 | Not Cancer Driver | No | 20 | 0.074074074074074 | 117 | 12 | 0.0444444444444444 | 0 |
| RPA3-201 | RPA3 | P35244 | Replication protein A 14 kDa subunit | chr7 | GO:0006284 | Not Cancer Driver | No | 10 | 0.0826446280991735 | 4 | 1 | 0.0082644628099173 | 0 |
| RPS3-217 | RPS3 | P23396 | Small ribosomal subunit protein uS3 | chr11 | GO:0006284 | Not Cancer Driver | No | 22 | 0.0905349794238683 | 48 | 4 | 0.0164609053497942 | 0 |
| SIRT6-202 | SIRT6 | Q8N6T7 | NAD-dependent protein deacylase sirtuin-6 | chr19 | GO:0006284 | Not Cancer Driver | No | 24 | 0.0676056338028169 | 165 | 6 | 0.0169014084507042 | 0 |
| SMUG1-226 | SMUG1 | Q53HV7 | Single-strand selective monofunctional uracil DNA glycosylase | chr12 | GO:0006284 | Not Cancer Driver | No | 27 | 0.1 | 47 | 1 | 0.0037037037037037 | 0 |
| TDG-202 | TDG | Q13569 | G/T mismatch-specific thymine DNA glycosylase | chr12 | GO:0006284 | Not Cancer Driver | No | 45 | 0.1097560975609756 | 186 | 21 | 0.0512195121951219 | 0 |
| UNG-201 | UNG | P13051 | Uracil-DNA glycosylase | chr12 | GO:0006284 | Not Cancer Driver | No | 28 | 0.0894568690095846 | 96 | 12 | 0.0383386581469648 | 1 |
| USP47-203 | USP47 | Q96K76 | Ubiquitin carboxyl-terminal hydrolase 47 | chr11 | GO:0006284 | Not Cancer Driver | No | 86 | 0.0625454545454545 | 426 | 24 | 0.0174545454545454 | 0 |
| WRN-201 | WRN | Q14191 | Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN | chr8 | GO:0006284 | Census, Compendium | Yes | 133 | 0.092877094972067 | 374 | 29 | 0.0202513966480446 | 2 |
| XPA-201 | XPA | P23025 | DNA repair protein complementing XP-A cells | chr9 | GO:0006284 | Census | Yes | 12 | 0.0439560439560439 | 121 | 6 | 0.0219780219780219 | 5 |
| XRCC1-201 | XRCC1 | P18887 | DNA repair protein XRCC1 | chr19 | GO:0006284 | Not Cancer Driver | No | 58 | 0.0916271721958925 | 431 | 39 | 0.0616113744075829 | 1 |