Total number of protein in "GO:0006298" GO term: 26
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ABL1-201 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0006298 | Census, Compendium | Yes | 106 | 0.0938053097345132 | 609 | 53 | 0.0469026548672566 | 2 |
EXO1-202 | EXO1 | Q9UQ84 | Exonuclease 1 | chr1 | GO:0006298 | Not Cancer Driver | No | 92 | 0.1087470449172576 | 478 | 60 | 0.0709219858156028 | 0 |
LIG1-201 | LIG1 | P18858 | DNA ligase 1 | chr19 | GO:0006298 | Not Cancer Driver | No | 99 | 0.1077257889009793 | 400 | 50 | 0.0544069640914037 | 3 |
MLH1-201 | MLH1 | P40692 | DNA mismatch repair protein Mlh1 | chr3 | GO:0006298 | Census | Yes | 65 | 0.0859788359788359 | 208 | 13 | 0.0171957671957671 | 77 |
MLH3-201 | MLH3 | Q9UHC1 | DNA mismatch repair protein Mlh3 | chr14 | GO:0006298 | Not Cancer Driver | No | 103 | 0.0708878183069511 | 598 | 43 | 0.0295939435650378 | 9 |
MSH2-201 | MSH2 | P43246 | DNA mismatch repair protein Msh2 | chr2 | GO:0006298 | Census | Yes | 55 | 0.0588865096359743 | 37 | 1 | 0.0010706638115631 | 63 |
MSH3-201 | MSH3 | P20585 | DNA mismatch repair protein Msh3 | chr5 | GO:0006298 | Not Cancer Driver | No | 65 | 0.0571679859278803 | 218 | 11 | 0.0096745822339489 | 0 |
MSH4-201 | MSH4 | O15457 | MutS protein homolog 4 | chr1 | GO:0006298 | Not Cancer Driver | No | 122 | 0.1303418803418803 | 198 | 32 | 0.0341880341880341 | 3 |
MSH5-203 | MSH5 | O43196 | MutS protein homolog 5 | chr6 | GO:0006298 | Not Cancer Driver | No | 67 | 0.0803357314148681 | 86 | 6 | 0.0071942446043165 | 1 |
MSH5-SAPCD1-207 | MSH5 | O43196 | MutS protein homolog 5 | chr6 | GO:0006298 | Not Cancer Driver | No | 67 | 0.0787309048178613 | 92 | 6 | 0.0070505287896592 | 1 |
MSH6-201 | MSH6 | P52701 | DNA mismatch repair protein Msh6 | chr2 | GO:0006298 | Census | Yes | 92 | 0.0676470588235294 | 389 | 26 | 0.0191176470588235 | 6 |
MUTYH-245 | MUTYH | Q9UIF7 | Adenine DNA glycosylase | chr1 | GO:0006298 | Census | Yes | 71 | 0.13003663003663 | 198 | 21 | 0.0384615384615384 | 23 |
PCNA-201 | PCNA | P12004 | Proliferating cell nuclear antigen | chr20 | GO:0006298 | Not Cancer Driver | No | 19 | 0.0727969348659003 | 22 | 2 | 0.0076628352490421 | 1 |
PMS1-213 | PMS1 | P54277 | PMS1 protein homolog 1 | chr2 | GO:0006298 | Census | Yes | 86 | 0.0922746781115879 | 284 | 31 | 0.0332618025751072 | 0 |
PMS2-201 | PMS2 | P54278 | Mismatch repair endonuclease PMS2 | chr7 | GO:0006298 | Census, Compendium | Yes | 85 | 0.0986078886310904 | 336 | 30 | 0.0348027842227378 | 8 |
POLD3-201 | POLD3 | Q15054 | DNA polymerase delta subunit 3 | chr11 | GO:0006298 | Not Cancer Driver | No | 34 | 0.0729613733905579 | 327 | 26 | 0.055793991416309 | 0 |
RNASEH2A-201 | RNASEH2A | O75792 | Ribonuclease H2 subunit A | chr19 | GO:0006298 | Not Cancer Driver | No | 29 | 0.0969899665551839 | 31 | 1 | 0.0033444816053511 | 7 |
RNASEH2B-201 | RNASEH2B | Q5TBB1 | Ribonuclease H2 subunit B | chr13 | GO:0006298 | Not Cancer Driver | No | 24 | 0.0769230769230769 | 84 | 8 | 0.0256410256410256 | 15 |
RNASEH2C-201 | RNASEH2C | Q8TDP1 | Ribonuclease H2 subunit C | chr11 | GO:0006298 | Not Cancer Driver | No | 6 | 0.0365853658536585 | 80 | 3 | 0.0182926829268292 | 7 |
RPA1-201 | RPA1 | P27694 | Replication protein A 70 kDa DNA-binding subunit | chr17 | GO:0006298 | Not Cancer Driver | No | 45 | 0.073051948051948 | 98 | 7 | 0.0113636363636363 | 1 |
RPA2-203 | RPA2 | P15927 | Replication protein A 32 kDa subunit | chr1 | GO:0006298 | Not Cancer Driver | No | 20 | 0.074074074074074 | 117 | 12 | 0.0444444444444444 | 0 |
RPA3-201 | RPA3 | P35244 | Replication protein A 14 kDa subunit | chr7 | GO:0006298 | Not Cancer Driver | No | 10 | 0.0826446280991735 | 4 | 1 | 0.0082644628099173 | 0 |
SETD2-202 | SETD2 | Q9BYW2 | Histone-lysine N-methyltransferase SETD2 | chr3 | GO:0006298 | Census, Compendium | Yes | 233 | 0.0908736349453978 | 1949 | 144 | 0.0561622464898595 | 4 |
TP73-208 | TP73 | O15350 | Tumor protein p73 | chr1 | GO:0006298 | Not Cancer Driver | No | 67 | 0.1053459119496855 | 446 | 45 | 0.070754716981132 | 0 |
TREX1-205 | TREX1 | Q9NSU2 | Three-prime repair exonuclease 1 | chr3 | GO:0006298 | Not Cancer Driver | No | 24 | 0.0764331210191082 | 98 | 7 | 0.0222929936305732 | 17 |
XPC-201 | XPC | Q01831 | DNA repair protein complementing XP-C cells | chr3 | GO:0006298 | Census, Compendium | Yes | 64 | 0.0680851063829787 | 484 | 34 | 0.0361702127659574 | 2 |