Total number of protein in "GO:0006606" GO term: 100
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABRA-201 | ABRA | Q8N0Z2 | Actin-binding Rho-activating protein | chr8 | GO:0006606 | Not Cancer Driver | No | 83 | 0.2178477690288714 | 285 | 69 | 0.1811023622047244 | 0 |
| AKIRIN2-201 | AKIRIN2 | Q53H80 | Akirin-2 | chr6 | GO:0006606 | Not Cancer Driver | No | 19 | 0.0935960591133004 | 124 | 11 | 0.0541871921182266 | 0 |
| AKT1-218 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0006606 | Census, Compendium | Yes | 99 | 0.20625 | 158 | 19 | 0.0395833333333333 | 4 |
| APPL1-201 | APPL1 | Q9UKG1 | DCC-interacting protein 13-alpha | chr3 | GO:0006606 | Not Cancer Driver | No | 35 | 0.0493653032440056 | 293 | 18 | 0.0253878702397743 | 1 |
| APPL2-201 | APPL2 | Q8NEU8 | DCC-interacting protein 13-beta | chr12 | GO:0006606 | Not Cancer Driver | No | 49 | 0.0737951807228915 | 149 | 8 | 0.0120481927710843 | 0 |
| ATF2-201 | ATF2 | P15336 | Cyclic AMP-dependent transcription factor ATF-2 | chr2 | GO:0006606 | Not Cancer Driver | No | 42 | 0.0831683168316831 | 451 | 36 | 0.0712871287128712 | 0 |
| BCL3-201 | BCL3 | P20749 | B-cell lymphoma 3 protein | chr19 | GO:0006606 | Census | Yes | 28 | 0.0616740088105726 | 259 | 8 | 0.0176211453744493 | 0 |
| CDKN1A-201 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | GO:0006606 | Census, Compendium | Yes | 38 | 0.2317073170731707 | 121 | 25 | 0.1524390243902439 | 0 |
| CRY2-211 | CRY2 | Q49AN0 | Cryptochrome-2 | chr11 | GO:0006606 | Not Cancer Driver | No | 54 | 0.0910623946037099 | 100 | 8 | 0.0134907251264755 | 0 |
| CSE1L-201 | CSE1L | P55060 | Exportin-2 | chr20 | GO:0006606 | Not Cancer Driver | No | 77 | 0.0792996910401647 | 32 | 4 | 0.0041194644696189 | 0 |
| DRD1-201 | DRD1 | P21728 | D(1A) dopamine receptor | chr5 | GO:0006606 | Not Cancer Driver | No | 49 | 0.1098654708520179 | 30 | 3 | 0.0067264573991031 | 0 |
| E2F3-201 | E2F3 | O00716 | Transcription factor E2F3 | chr6 | GO:0006606 | Not Cancer Driver | No | 27 | 0.0580645161290322 | 253 | 11 | 0.0236559139784946 | 0 |
| EIF4ENIF1-201 | EIF4ENIF1 | Q9NRA8 | Eukaryotic translation initiation factor 4E transporter | chr22 | GO:0006606 | Not Cancer Driver | No | 86 | 0.0873096446700507 | 902 | 75 | 0.0761421319796954 | 0 |
| ELAVL1-201 | ELAVL1 | Q15717 | ELAV-like protein 1 | chr19 | GO:0006606 | Not Cancer Driver | No | 54 | 0.1656441717791411 | 43 | 5 | 0.0153374233128834 | 0 |
| ENST00000649896 | POLA2 | Q14181 | DNA polymerase alpha subunit B | chr11 | GO:0006606 | Not Cancer Driver | No | 45 | 0.0774526678141136 | 121 | 15 | 0.0258175559380378 | 0 |
| FAM53A-201 | FAM53A | Q6NSI3 | Protein FAM53A | chr4 | GO:0006606 | Not Cancer Driver | No | 24 | 0.0603015075376884 | 381 | 24 | 0.0603015075376884 | 0 |
| FAM53B-202 | FAM53B | Q14153 | Protein FAM53B | chr10 | GO:0006606 | Not Cancer Driver | No | 43 | 0.1018957345971564 | 254 | 28 | 0.0663507109004739 | 0 |
| FAM53C-201 | FAM53C | Q9NYF3 | Protein FAM53C | chr5 | GO:0006606 | Not Cancer Driver | No | 40 | 0.1020408163265306 | 296 | 35 | 0.0892857142857142 | 0 |
| FGF9-201 | FGF9 | P31371 | Fibroblast growth factor 9 | chr13 | GO:0006606 | Not Cancer Driver | No | 33 | 0.1586538461538461 | 43 | 8 | 0.0384615384615384 | 1 |
| GCKR-201 | GCKR | Q14397 | Glucokinase regulatory protein | chr2 | GO:0006606 | Not Cancer Driver | No | 71 | 0.1136 | 85 | 22 | 0.0352 | 0 |
| GLI3-201 | GLI3 | P10071 | Transcriptional activator GLI3 | chr7 | GO:0006606 | Not Cancer Driver | No | 308 | 0.1949367088607595 | 1362 | 270 | 0.170886075949367 | 7 |
| HEATR3-201 | HEATR3 | Q7Z4Q2 | HEAT repeat-containing protein 3 | chr16 | GO:0006606 | Not Cancer Driver | No | 56 | 0.0823529411764705 | 134 | 7 | 0.0102941176470588 | 2 |
| HIKESHI-201 | HIKESHI | Q53FT3 | Protein Hikeshi | chr11 | GO:0006606 | Not Cancer Driver | No | 16 | 0.0812182741116751 | 2 | 0 | 0.0 | 1 |
| IL33-206 | IL33 | O95760 | Interleukin-33 | chr9 | GO:0006606 | Not Cancer Driver | No | 31 | 0.1148148148148148 | 47 | 5 | 0.0185185185185185 | 0 |
| ING1-203 | ING1 | Q9UK53 | Inhibitor of growth protein 1 | chr13 | GO:0006606 | Compendium | Yes | 55 | 0.1303317535545023 | 213 | 27 | 0.0639810426540284 | 3 |
| IPO11-201 | IPO11 | Q9UI26 | Importin-11 | chr5 | GO:0006606 | Not Cancer Driver | No | 62 | 0.0635897435897435 | 66 | 4 | 0.0041025641025641 | 0 |
| IPO13-202 | IPO13 | O94829 | Importin-13 | chr1 | GO:0006606 | Not Cancer Driver | No | 74 | 0.0768431983385254 | 42 | 5 | 0.0051921079958463 | 0 |
| IPO4-201 | IPO4 | Q8TEX9 | Importin-4 | chr14 | GO:0006606 | Not Cancer Driver | No | 78 | 0.0721554116558741 | 87 | 3 | 0.0027752081406105 | 0 |
| IPO5-230 | IPO5 | O00410 | Importin-5 | chr13 | GO:0006606 | Not Cancer Driver | No | 82 | 0.0747493163172288 | 52 | 2 | 0.0018231540565177 | 0 |
| IPO7-201 | IPO7 | O95373 | Importin-7 | chr11 | GO:0006606 | Not Cancer Driver | No | 108 | 0.1040462427745664 | 202 | 25 | 0.0240847784200385 | 0 |
| IPO8-201 | IPO8 | O15397 | Importin-8 | chr12 | GO:0006606 | Not Cancer Driver | No | 93 | 0.0896817743490838 | 111 | 10 | 0.0096432015429122 | 3 |
| IPO9-201 | IPO9 | Q96P70 | Importin-9 | chr1 | GO:0006606 | Not Cancer Driver | No | 101 | 0.0970220941402497 | 103 | 15 | 0.0144092219020172 | 0 |
| KCNQ3-201 | KCNQ3 | O43525 | Potassium voltage-gated channel subfamily KQT member 3 | chr8 | GO:0006606 | Not Cancer Driver | No | 209 | 0.2396788990825688 | 414 | 97 | 0.1112385321100917 | 3 |
| KPNA1-201 | KPNA1 | P52294 | Importin subunit alpha-5 | chr3 | GO:0006606 | Not Cancer Driver | No | 48 | 0.0892193308550185 | 122 | 16 | 0.0297397769516728 | 0 |
| KPNA2-201 | KPNA2 | P52292 | Importin subunit alpha-1 | chr17 | GO:0006606 | Not Cancer Driver | No | 54 | 0.1020793950850661 | 130 | 14 | 0.0264650283553875 | 0 |
| KPNA3-201 | KPNA3 | O00505 | Importin subunit alpha-4 | chr13 | GO:0006606 | Not Cancer Driver | No | 47 | 0.0902111324376199 | 108 | 7 | 0.0134357005758157 | 5 |
| KPNA4-201 | KPNA4 | O00629 | Importin subunit alpha-3 | chr3 | GO:0006606 | Not Cancer Driver | No | 37 | 0.0710172744721689 | 115 | 5 | 0.0095969289827255 | 0 |
| KPNA5-202 | KPNA5 | O15131 | Importin subunit alpha-6 | chr6 | GO:0006606 | Not Cancer Driver | No | 48 | 0.0890538033395176 | 133 | 8 | 0.0148423005565862 | 0 |
| KPNA6-201 | KPNA6 | O60684 | Importin subunit alpha-7 | chr1 | GO:0006606 | Not Cancer Driver | No | 50 | 0.0932835820895522 | 97 | 13 | 0.0242537313432835 | 0 |
| KPNA7-201 | KPNA7 | A9QM74 | Importin subunit alpha-8 | chr7 | GO:0006606 | Not Cancer Driver | No | 19 | 0.0368217054263565 | 66 | 3 | 0.005813953488372 | 0 |
| KPNB1-201 | KPNB1 | Q14974 | Importin subunit beta-1 | chr17 | GO:0006606 | Not Cancer Driver | No | 79 | 0.0901826484018264 | 95 | 9 | 0.0102739726027397 | 0 |
| LMNA-205 | LMNA | P02545 | Prelamin-A/C | chr1 | GO:0006606 | Census | Yes | 50 | 0.0753012048192771 | 547 | 34 | 0.0512048192771084 | 117 |
| LRRK2-201 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | GO:0006606 | Not Cancer Driver | No | 402 | 0.1590819153146023 | 91 | 13 | 0.0051444400474871 | 20 |
| MED1-201 | MED1 | Q15648 | Mediator of RNA polymerase II transcription subunit 1 | chr17 | GO:0006606 | Not Cancer Driver | No | 81 | 0.0512333965844402 | 1104 | 50 | 0.0316255534471853 | 0 |
| MMP12-201 | MMP12 | P39900 | Macrophage metalloelastase | chr11 | GO:0006606 | Not Cancer Driver | No | 0 | 0.0 | 29 | 0 | 0.0 | 0 |
| NF1-202 | NF1 | P21359 | Neurofibromin | chr17 | GO:0006606 | Census, Compendium | Yes | 285 | 0.1003874603733709 | 406 | 36 | 0.0126805213103205 | 75 |
| NFKBIA-201 | NFKBIA | P25963 | NF-kappa-B inhibitor alpha | chr14 | GO:0006606 | Compendium | Yes | 34 | 0.1072555205047318 | 102 | 10 | 0.0315457413249211 | 1 |
| NOTCH1-204 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | GO:0006606 | Census, Compendium | Yes | 312 | 0.1221135029354207 | 690 | 71 | 0.0277886497064579 | 3 |
| NPAP1-201 | NPAP1 | Q9NZP6 | Nuclear pore-associated protein 1 | chr15 | GO:0006606 | Not Cancer Driver | No | 482 | 0.416955017301038 | 1015 | 422 | 0.3650519031141868 | 0 |
| NUP107-201 | NUP107 | P57740 | Nuclear pore complex protein Nup107 | chr12 | GO:0006606 | Not Cancer Driver | No | 89 | 0.0962162162162162 | 185 | 21 | 0.0227027027027027 | 5 |
| NUP133-201 | NUP133 | Q8WUM0 | Nuclear pore complex protein Nup133 | chr1 | GO:0006606 | Not Cancer Driver | No | 115 | 0.0994809688581314 | 116 | 10 | 0.0086505190311418 | 3 |
| NUP153-201 | NUP153 | P49790 | Nuclear pore complex protein Nup153 | chr6 | GO:0006606 | Not Cancer Driver | No | 125 | 0.0847457627118644 | 1149 | 101 | 0.0684745762711864 | 0 |
| NUP155-201 | NUP155 | O75694 | Nuclear pore complex protein Nup155 | chr5 | GO:0006606 | Not Cancer Driver | No | 128 | 0.0920201294033069 | 221 | 17 | 0.0122214234363767 | 1 |
| NUP188-201 | NUP188 | Q5SRE5 | Nucleoporin NUP188 | chr9 | GO:0006606 | Not Cancer Driver | No | 134 | 0.0766152086906803 | 152 | 18 | 0.0102915951972555 | 0 |
| NUP214-201 | NUP214 | P35658 | Nuclear pore complex protein Nup214 | chr9 | GO:0006606 | Census, Compendium | Yes | 168 | 0.0803827751196172 | 1483 | 113 | 0.054066985645933 | 2 |
| NUP50-201 | NUP50 | Q9UKX7 | Nuclear pore complex protein Nup50 | chr22 | GO:0006606 | Not Cancer Driver | No | 43 | 0.0918803418803418 | 335 | 30 | 0.0641025641025641 | 0 |
| NUP62-201 | NUP62 | P37198 | Nuclear pore glycoprotein p62 | chr19 | GO:0006606 | Not Cancer Driver | No | 55 | 0.1053639846743295 | 378 | 39 | 0.0747126436781609 | 1 |
| NUP85-201 | NUP85 | Q9BW27 | Nuclear pore complex protein Nup85 | chr17 | GO:0006606 | Not Cancer Driver | No | 45 | 0.0685975609756097 | 32 | 1 | 0.0015243902439024 | 2 |
| NUP88-207 | NUP88 | Q99567 | Nuclear pore complex protein Nup88 | chr17 | GO:0006606 | Not Cancer Driver | No | 69 | 0.0931174089068826 | 148 | 21 | 0.0283400809716599 | 1 |
| NUP93-201 | NUP93 | Q8N1F7 | Nuclear pore complex protein Nup93 | chr16 | GO:0006606 | Not Cancer Driver | No | 69 | 0.0842490842490842 | 161 | 18 | 0.0219780219780219 | 3 |
| NUP98-203 | NUP98 | P52948 | Nuclear pore complex protein Nup98-Nup96 | chr11 | GO:0006606 | Census | Yes | 161 | 0.0886075949367088 | 1012 | 78 | 0.042927903137039 | 0 |
| NUTF2-201 | NUTF2 | P61970 | Nuclear transport factor 2 | chr16 | GO:0006606 | Not Cancer Driver | No | 16 | 0.1259842519685039 | 6 | 2 | 0.0157480314960629 | 0 |
| PHB2-203 | PHB2 | Q99623 | Prohibitin-2 | chr12 | GO:0006606 | Not Cancer Driver | No | 25 | 0.0836120401337792 | 26 | 4 | 0.0133779264214046 | 0 |
| PIK3R1-211 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | GO:0006606 | Census, Compendium | Yes | 122 | 0.1685082872928177 | 271 | 50 | 0.0690607734806629 | 2 |
| PML-201 | PML | P29590 | Protein PML | chr15 | GO:0006606 | Census, Compendium | Yes | 87 | 0.0986394557823129 | 312 | 28 | 0.0317460317460317 | 0 |
| POLA2-201 | POLA2 | Q14181 | DNA polymerase alpha subunit B | chr11 | GO:0006606 | Not Cancer Driver | No | 49 | 0.0819397993311036 | 102 | 15 | 0.0250836120401337 | 0 |
| POM121-202 | POM121 | Q96HA1 | Nuclear envelope pore membrane protein POM 121 | chr7 | GO:0006606 | Not Cancer Driver | No | 100 | 0.0800640512409927 | 1075 | 80 | 0.0640512409927942 | 0 |
| POM121C-206 | POM121C | A8CG34 | Nuclear envelope pore membrane protein POM 121C | chr7 | GO:0006606 | Not Cancer Driver | No | 63 | 0.0512611879576891 | 1123 | 59 | 0.0480065093572009 | 0 |
| POM121L2-202 | POM121L2 | Q96KW2 | POM121-like protein 2 | chr6 | GO:0006606 | Not Cancer Driver | No | 44 | 0.0425120772946859 | 816 | 32 | 0.0309178743961352 | 0 |
| PPP1R10-201 | PPP1R10 | Q96QC0 | Serine/threonine-protein phosphatase 1 regulatory subunit 10 | chr6 | GO:0006606 | Not Cancer Driver | No | 50 | 0.0531914893617021 | 798 | 40 | 0.0425531914893617 | 0 |
| PPP3CA-203 | PPP3CA | Q08209 | Protein phosphatase 3 catalytic subunit alpha | chr4 | GO:0006606 | Compendium | Yes | 63 | 0.1209213051823416 | 140 | 24 | 0.0460652591170825 | 7 |
| PPP3R1-201 | PPP3R1 | P63098 | Calcineurin subunit B type 1 | chr2 | GO:0006606 | Not Cancer Driver | No | 15 | 0.088235294117647 | 1 | 0 | 0.0 | 0 |
| PRICKLE1-201 | PRICKLE1 | Q96MT3 | Prickle-like protein 1 | chr12 | GO:0006606 | Not Cancer Driver | No | 118 | 0.1419975932611311 | 485 | 71 | 0.0854392298435619 | 3 |
| PTTG1IP-201 | PTTG1IP | P53801 | Pituitary tumor-transforming gene 1 protein-interacting protein | chr21 | GO:0006606 | Not Cancer Driver | No | 16 | 0.0888888888888888 | 30 | 6 | 0.0333333333333333 | 0 |
| RAN-212 | RAN | P62826 | GTP-binding nuclear protein Ran | chr12 | GO:0006606 | Not Cancer Driver | No | 18 | 0.0833333333333333 | 14 | 0 | 0.0 | 0 |
| RANBP17-219 | RANBP17 | Q9H2T7 | Ran-binding protein 17 | chr5 | GO:0006606 | Not Cancer Driver | No | 123 | 0.1130514705882353 | 14 | 1 | 0.0009191176470588 | 0 |
| RANBP6-201 | RANBP6 | O60518 | Ran-binding protein 6 | chr9 | GO:0006606 | Not Cancer Driver | No | 99 | 0.0895927601809954 | 46 | 3 | 0.0027149321266968 | 0 |
| RANGRF-201 | RANGRF | Q9HD47 | Ran guanine nucleotide release factor | chr17 | GO:0006606 | Not Cancer Driver | No | 6 | 0.032258064516129 | 42 | 3 | 0.0161290322580645 | 0 |
| RPAIN-203 | RPAIN | Q86UA6 | RPA-interacting protein | chr17 | GO:0006606 | Not Cancer Driver | No | 21 | 0.0958904109589041 | 31 | 4 | 0.0182648401826484 | 0 |
| SEC13-202 | SEC13 | P55735 | Protein SEC13 homolog | chr3 | GO:0006606 | Not Cancer Driver | No | 26 | 0.0807453416149068 | 36 | 4 | 0.0124223602484472 | 0 |
| SHH-201 | SHH | Q15465 | Sonic hedgehog protein | chr7 | GO:0006606 | Not Cancer Driver | No | 36 | 0.0779220779220779 | 139 | 11 | 0.0238095238095238 | 69 |
| SIX2-201 | SIX2 | Q9NPC8 | Homeobox protein SIX2 | chr2 | GO:0006606 | Census | Yes | 38 | 0.1305841924398625 | 151 | 16 | 0.0549828178694158 | 0 |
| SMO-201 | SMO | Q99835 | Protein smoothened | chr7 | GO:0006606 | Census, Compendium | Yes | 88 | 0.1118170266836086 | 242 | 20 | 0.025412960609911 | 1 |
| SNUPN-201 | SNUPN | O95149 | Snurportin-1 | chr15 | GO:0006606 | Not Cancer Driver | No | 31 | 0.0861111111111111 | 137 | 12 | 0.0333333333333333 | 0 |
| SPG11-201 | SPG11 | Q96JI7 | Spatacsin | chr15 | GO:0006606 | Not Cancer Driver | No | 175 | 0.0716332378223495 | 126 | 7 | 0.0028653295128939 | 1 |
| SPRN-202 | SPRN | Q5BIV9 | Shadow of prion protein | chr10 | GO:0006606 | Not Cancer Driver | No | 2 | 0.0132450331125827 | 75 | 0 | 0.0 | 0 |
| SQSTM1-202 | SQSTM1 | Q13501 | Sequestosome-1 | chr5 | GO:0006606 | Not Cancer Driver | No | 41 | 0.0931818181818181 | 271 | 24 | 0.0545454545454545 | 30 |
| STAT3-201 | STAT3 | P40763 | Signal transducer and activator of transcription 3 | chr17 | GO:0006606 | Census, Compendium | Yes | 93 | 0.1207792207792207 | 152 | 16 | 0.0207792207792207 | 15 |
| STK3-201 | STK3 | Q13188 | Serine/threonine-protein kinase 3 | chr8 | GO:0006606 | Not Cancer Driver | No | 48 | 0.0977596741344195 | 241 | 22 | 0.0448065173116089 | 0 |
| STK4-202 | STK4 | Q13043 | Serine/threonine-protein kinase 4 | chr20 | GO:0006606 | Not Cancer Driver | No | 49 | 0.1006160164271047 | 233 | 20 | 0.0410677618069815 | 0 |
| SYK-204 | SYK | P43405 | Tyrosine-protein kinase SYK | chr9 | GO:0006606 | Census | Yes | 75 | 0.1181102362204724 | 131 | 20 | 0.0314960629921259 | 4 |
| TMCO6-203 | TMCO6 | Q96DC7 | Transmembrane and coiled-coil domain-containing protein 6 | chr5 | GO:0006606 | Not Cancer Driver | No | 35 | 0.0709939148073022 | 76 | 3 | 0.0060851926977687 | 0 |
| TNPO1-201 | TNPO1 | Q92973 | Transportin-1 | chr5 | GO:0006606 | Not Cancer Driver | No | 66 | 0.0734966592427616 | 68 | 5 | 0.0055679287305122 | 0 |
| TNPO2-202 | TNPO2 | O14787 | Transportin-2 | chr19 | GO:0006606 | Not Cancer Driver | No | 77 | 0.0858416945373467 | 76 | 9 | 0.0100334448160535 | 10 |
| TNPO3-201 | TNPO3 | Q9Y5L0 | Transportin-3 | chr7 | GO:0006606 | Not Cancer Driver | No | 95 | 0.1029252437703141 | 12 | 1 | 0.0010834236186348 | 1 |
| TP53-201 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0006606 | Census, Compendium | Yes | 2742 | 6.977099236641221 | 282 | 1364 | 3.470737913486005 | 60 |
| TPR-201 | TPR | P12270 | Nucleoprotein TPR | chr1 | GO:0006606 | Census | Yes | 215 | 0.0909860347016504 | 1994 | 184 | 0.0778671180702496 | 0 |
| TRAF3IP2-201 | TRAF3IP2 | O43734 | E3 ubiquitin ligase TRAF3IP2 | chr6 | GO:0006606 | Not Cancer Driver | No | 47 | 0.0818815331010452 | 413 | 34 | 0.0592334494773519 | 2 |
| TSC2-201 | TSC2 | P49815 | Tuberin | chr16 | GO:0006606 | Census, Compendium | Yes | 156 | 0.0863309352517985 | 568 | 40 | 0.0221361372440509 | 49 |
| TXNIP-204 | TXNIP | Q9H3M7 | Thioredoxin-interacting protein | chr1 | GO:0006606 | Not Cancer Driver | No | 46 | 0.1176470588235294 | 77 | 10 | 0.0255754475703324 | 0 |