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Total number of protein in "GO:0006805" GO term:  110

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AADAC-201 AADAC P22760 Arylacetamide deacetylase chr3 GO:0006805 Not Cancer Driver No 58 0.1453634085213032 4 0 0.0 0
ABCB1-211 ABCB1 P08183 ATP-dependent translocase ABCB1 chr7 GO:0006805 Compendium Yes 275 0.21484375 103 15 0.01171875 0
ABCB11-206 ABCB11 O95342 Bile salt export pump chr2 GO:0006805 Not Cancer Driver No 167 0.1264193792581378 125 20 0.0151400454201362 21
ABCC1-202 ABCC1 P33527 Multidrug resistance-associated protein 1 chr16 GO:0006805 Not Cancer Driver No 157 0.1025473546701502 123 18 0.0117570215545395 1
ABCC2-203 ABCC2 Q92887 ATP-binding cassette sub-family C member 2 chr10 GO:0006805 Not Cancer Driver No 124 0.0802588996763754 102 16 0.0103559870550161 4
ABCC3-201 ABCC3 O15438 ATP-binding cassette sub-family C member 3 chr17 GO:0006805 Not Cancer Driver No 156 0.1021611001964636 114 11 0.0072036673215455 0
ABCC4-214 ABCC4 O15439 ATP-binding cassette sub-family C member 4 chr13 GO:0006805 Not Cancer Driver No 120 0.090566037735849 99 5 0.0037735849056603 0
ABCC5-202 ABCC5 O15440 ATP-binding cassette sub-family C member 5 chr3 GO:0006805 Not Cancer Driver No 140 0.0974251913709116 257 19 0.0132219902574808 0
ACSM1-204 ACSM1 Q08AH1 Acyl-coenzyme A synthetase ACSM1, mitochondrial chr16 GO:0006805 Not Cancer Driver No 92 0.1594454072790294 65 11 0.0190641247833622 0
ACSM2B-201 ACSM2B Q68CK6 Acyl-coenzyme A synthetase ACSM2B, mitochondrial chr16 GO:0006805 Not Cancer Driver No 182 0.315424610051993 46 22 0.0381282495667244 0
ADA-201 ADA P00813 Adenosine deaminase chr20 GO:0006805 Not Cancer Driver No 43 0.1184573002754821 45 9 0.024793388429752 22
AHR-201 AHR P35869 Aryl hydrocarbon receptor chr7 GO:0006805 Not Cancer Driver No 95 0.1120283018867924 353 55 0.0648584905660377 0
AHRR-211 AHRR A9YTQ3 Aryl hydrocarbon receptor repressor chr5 GO:0006805 Not Cancer Driver No 90 0.1291248206599713 458 53 0.0760401721664275 0
AIP-201 AIP O00170 AH receptor-interacting protein chr11 GO:0006805 Not Cancer Driver No 26 0.0787878787878787 64 7 0.0212121212121212 1
AKR1C1-202 AKR1C1 Q04828 Aldo-keto reductase family 1 member C1 chr10 GO:0006805 Not Cancer Driver No 41 0.1269349845201238 1 0 0.0 0
ALDH3A1-201 ALDH3A1 P30838 Aldehyde dehydrogenase, dimeric NADP-preferring chr17 GO:0006805 Not Cancer Driver No 55 0.1214128035320088 36 5 0.0110375275938189 0
AOC2-201 AOC2 O75106 Retina-specific copper amine oxidase chr17 GO:0006805 Not Cancer Driver No 75 0.0992063492063492 112 10 0.0132275132275132 0
AOX1-202 AOX1 Q06278 Aldehyde oxidase chr2 GO:0006805 Not Cancer Driver No 173 0.1292974588938714 71 8 0.0059790732436472 0
BCHE-201 BCHE P06276 Cholinesterase chr3 GO:0006805 Not Cancer Driver No 157 0.260797342192691 14 3 0.0049833887043189 37
BPHL-203 BPHL Q86WA6 Valacyclovir hydrolase chr6 GO:0006805 Not Cancer Driver No 22 0.0756013745704467 12 0 0.0 0
CAD-201 CAD P27708 CAD protein chr2 GO:0006805 Not Cancer Driver No 211 0.0948314606741573 368 27 0.0121348314606741 1
CBR1-201 CBR1 P16152 Carbonyl reductase [NADPH] 1 chr21 GO:0006805 Not Cancer Driver No 20 0.0722021660649819 64 9 0.0324909747292418 0
CBR3-201 CBR3 O75828 Carbonyl reductase [NADPH] 3 chr21 GO:0006805 Not Cancer Driver No 10 0.0361010830324909 67 3 0.0108303249097472 0
CES2-201 CES2 O00748 Cocaine esterase chr16 GO:0006805 Not Cancer Driver No 43 0.0769230769230769 79 7 0.0125223613595706 0
CES3-201 CES3 Q6UWW8 Carboxylesterase 3 chr16 GO:0006805 Not Cancer Driver No 72 0.1260945709281961 112 12 0.021015761821366 0
CMBL-201 CMBL Q96DG6 Carboxymethylenebutenolidase homolog chr5 GO:0006805 Not Cancer Driver No 23 0.0938775510204081 0 0 0.0 0
CYB5B-201 CYB5B O43169 Cytochrome b5 type B chr16 GO:0006805 Not Cancer Driver No 16 0.1066666666666666 59 2 0.0133333333333333 0
CYP1A1-201 CYP1A1 P04798 Cytochrome P450 1A1 chr15 GO:0006805 Not Cancer Driver No 55 0.107421875 17 1 0.001953125 0
CYP1A2-201 CYP1A2 P05177 Cytochrome P450 1A2 chr15 GO:0006805 Not Cancer Driver No 75 0.1453488372093023 23 2 0.003875968992248 0
CYP1B1-205 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0006805 Not Cancer Driver No 41 0.0755064456721915 33 3 0.005524861878453 39
CYP26A1-201 CYP26A1 O43174 Cytochrome P450 26A1 chr10 GO:0006805 Not Cancer Driver No 57 0.1146881287726358 9 1 0.0020120724346076 0
CYP26B1-201 CYP26B1 Q9NR63 Cytochrome P450 26B1 chr2 GO:0006805 Not Cancer Driver No 91 0.177734375 10 2 0.00390625 2
CYP2A13-201 CYP2A13 Q16696 Cytochrome P450 2A13 chr19 GO:0006805 Not Cancer Driver No 97 0.1963562753036437 39 9 0.0182186234817813 0
CYP2A6-201 CYP2A6 P11509 Cytochrome P450 2A6 chr19 GO:0006805 Not Cancer Driver No 85 0.1720647773279352 41 10 0.020242914979757 0
CYP2A7-202 CYP2A7 P20853 Cytochrome P450 2A7 chr19 GO:0006805 Not Cancer Driver No 68 0.1376518218623481 40 7 0.0141700404858299 0
CYP2B6-201 CYP2B6 P20813 Cytochrome P450 2B6 chr19 GO:0006805 Not Cancer Driver No 98 0.1995926680244399 41 10 0.020366598778004 0
CYP2C18-201 CYP2C18 P33260 Cytochrome P450 2C18 chr10 GO:0006805 Not Cancer Driver No 92 0.1877551020408163 11 1 0.0020408163265306 0
CYP2C19-201 CYP2C19 P33261 Cytochrome P450 2C19 chr10 GO:0006805 Not Cancer Driver No 125 0.2551020408163265 33 10 0.0204081632653061 0
CYP2C8-201 CYP2C8 P10632 Cytochrome P450 2C8 chr10 GO:0006805 Census, Compendium Yes 85 0.173469387755102 30 10 0.0204081632653061 0
CYP2C9-201 CYP2C9 P11712 Cytochrome P450 2C9 chr10 GO:0006805 Not Cancer Driver No 94 0.1918367346938775 36 12 0.0244897959183673 0
CYP2D6-204 CYP2D6 P10635 Cytochrome P450 2D6 chr22 GO:0006805 Not Cancer Driver No 52 0.1046277665995975 66 3 0.0060362173038229 0
CYP2E1-201 CYP2E1 P05181 Cytochrome P450 2E1 chr10 GO:0006805 Not Cancer Driver No 66 0.1338742393509127 21 5 0.0101419878296146 0
CYP2F1-201 CYP2F1 P24903 Cytochrome P450 2F1 chr19 GO:0006805 Not Cancer Driver No 64 0.130346232179226 2 0 0.0 0
CYP2J2-201 CYP2J2 P51589 Cytochrome P450 2J2 chr1 GO:0006805 Not Cancer Driver No 35 0.0697211155378486 63 4 0.0079681274900398 0
CYP2R1-201 CYP2R1 Q6VVX0 Vitamin D 25-hydroxylase chr11 GO:0006805 Not Cancer Driver No 33 0.0658682634730539 5 0 0.0 1
CYP2S1-201 CYP2S1 Q96SQ9 Cytochrome P450 2S1 chr19 GO:0006805 Not Cancer Driver No 59 0.117063492063492 46 8 0.0158730158730158 0
CYP2U1-201 CYP2U1 Q7Z449 Cytochrome P450 2U1 chr4 GO:0006805 Not Cancer Driver No 29 0.0533088235294117 39 1 0.0018382352941176 4
CYP2W1-201 CYP2W1 Q8TAV3 Cytochrome P450 2W1 chr7 GO:0006805 Not Cancer Driver No 40 0.0816326530612244 56 4 0.0081632653061224 0
CYP3A4-206 CYP3A4 P08684 Cytochrome P450 3A4 chr7 GO:0006805 Not Cancer Driver No 63 0.125248508946322 22 2 0.003976143141153 1
CYP3A5-201 CYP3A5 P20815 Cytochrome P450 3A5 chr7 GO:0006805 Not Cancer Driver No 44 0.0876494023904382 38 5 0.0099601593625498 0
CYP3A7-201 CYP3A7 P24462 Cytochrome P450 3A7 chr7 GO:0006805 Not Cancer Driver No 65 0.1292246520874751 17 5 0.0099403578528827 0
CYP3A7-CYP3A51P-202 CYP3A7 P24462 Cytochrome P450 3A7 chr7 GO:0006805 Not Cancer Driver No 65 0.1292246520874751 21 5 0.0099403578528827 0
CYP46A1-201 CYP46A1 Q9Y6A2 Cholesterol 24-hydroxylase chr14 GO:0006805 Not Cancer Driver No 71 0.142 23 2 0.004 0
CYP4F12-215 CYP4F12 Q9HCS2 Cytochrome P450 4F12 chr19 GO:0006805 Not Cancer Driver No 107 0.2041984732824427 18 2 0.0038167938931297 0
CYP4F2-202 CYP4F2 P78329 Cytochrome P450 4F2 chr19 GO:0006805 Not Cancer Driver No 110 0.2115384615384615 17 2 0.0038461538461538 0
ENST00000637807 AHR P35869 Aryl hydrocarbon receptor chr7 GO:0006805 Not Cancer Driver No 90 0.1129234629861982 304 51 0.0639899623588456 0
EPHX1-201 EPHX1 P07099 Epoxide hydrolase 1 chr1 GO:0006805 Not Cancer Driver No 63 0.1384615384615384 7 0 0.0 0
FMO1-208 FMO1 Q01740 Flavin-containing monooxygenase 1 chr1 GO:0006805 Not Cancer Driver No 112 0.2105263157894736 3 0 0.0 0
FMO2-201 FMO2 Q99518 Flavin-containing monooxygenase 2 chr1 GO:0006805 Not Cancer Driver No 88 0.1644859813084112 3 0 0.0 0
FMO5-201 FMO5 P49326 Flavin-containing monooxygenase 5 chr1 GO:0006805 Not Cancer Driver No 59 0.1106941838649155 32 3 0.0056285178236397 0
GLYAT-202 GLYAT Q6IB77 Glycine N-acyltransferase chr11 GO:0006805 Not Cancer Driver No 62 0.2094594594594594 9 2 0.0067567567567567 0
GSTA1-201 GSTA1 P08263 Glutathione S-transferase A1 chr6 GO:0006805 Not Cancer Driver No 40 0.1801801801801801 17 2 0.009009009009009 0
GSTA2-201 GSTA2 P09210 Glutathione S-transferase A2 chr6 GO:0006805 Not Cancer Driver No 36 0.1621621621621621 20 3 0.0135135135135135 0
GSTA3-201 GSTA3 Q16772 Glutathione S-transferase A3 chr6 GO:0006805 Not Cancer Driver No 17 0.0765765765765765 16 4 0.018018018018018 0
GSTA4-203 GSTA4 O15217 Glutathione S-transferase A4 chr6 GO:0006805 Not Cancer Driver No 12 0.054054054054054 11 1 0.0045045045045045 0
GSTA5-201 GSTA5 Q7RTV2 Glutathione S-transferase A5 chr6 GO:0006805 Not Cancer Driver No 31 0.1396396396396396 16 0 0.0 0
GSTO2-201 GSTO2 Q9H4Y5 Glutathione S-transferase omega-2 chr10 GO:0006805 Not Cancer Driver No 17 0.0699588477366255 18 0 0.0 0
GSTP1-202 GSTP1 P09211 Glutathione S-transferase P chr11 GO:0006805 Not Cancer Driver No 23 0.1095238095238095 0 0 0.0 0
GUK1-209 GUK1 Q16774 Guanylate kinase chr1 GO:0006805 Not Cancer Driver No 17 0.0862944162436548 73 6 0.0304568527918781 0
HNF4A-201 HNF4A P41235 Hepatocyte nuclear factor 4-alpha chr20 GO:0006805 Not Cancer Driver No 113 0.2383966244725738 127 44 0.0928270042194092 5
NAT1-201 NAT1 P18440 Arylamine N-acetyltransferase 1 chr8 GO:0006805 Not Cancer Driver No 24 0.0827586206896551 0 0 0.0 0
NAT2-201 NAT2 P11245 Arylamine N-acetyltransferase 2 chr8 GO:0006805 Not Cancer Driver No 35 0.1206896551724138 0 0 0.0 0
NCEH1-204 NCEH1 Q6PIU2 Neutral cholesterol ester hydrolase 1 chr3 GO:0006805 Not Cancer Driver No 39 0.0955882352941176 3 0 0.0 0
NQO1-201 NQO1 P15559 NAD(P)H dehydrogenase [quinone] 1 chr16 GO:0006805 Not Cancer Driver No 11 0.0401459854014598 10 0 0.0 0
NR1I2-202 NR1I2 O75469 Nuclear receptor subfamily 1 group I member 2 chr3 GO:0006805 Not Cancer Driver No 45 0.1036866359447004 82 9 0.02073732718894 0
POR-218 POR P16435 NADPH--cytochrome P450 reductase chr7 GO:0006805 Not Cancer Driver No 49 0.0723781388478582 94 4 0.0059084194977843 9
RORA-203 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0006805 Not Cancer Driver No 43 0.0822179732313575 181 11 0.0210325047801147 4
RORC-201 RORC P51449 Nuclear receptor ROR-gamma chr1 GO:0006805 Not Cancer Driver No 81 0.1563706563706563 187 31 0.0598455598455598 1
S100A12-201 S100A12 P80511 Protein S100-A12 chr1 GO:0006805 Not Cancer Driver No 11 0.1195652173913043 1 0 0.0 0
SLC22A1-202 SLC22A1 O15245 Solute carrier family 22 member 1 chr6 GO:0006805 Not Cancer Driver No 48 0.0866425992779783 12 0 0.0 0
SLC22A7-202 SLC22A7 Q9Y694 Solute carrier family 22 member 7 chr6 GO:0006805 Not Cancer Driver No 93 0.1697080291970802 50 3 0.0054744525547445 0
SLC28A2-201 SLC28A2 O43868 Sodium/nucleoside cotransporter 2 chr15 GO:0006805 Not Cancer Driver No 72 0.1094224924012158 37 5 0.0075987841945288 0
SLC28A3-201 SLC28A3 Q9HAS3 Solute carrier family 28 member 3 chr9 GO:0006805 Not Cancer Driver No 79 0.1143270622286541 84 6 0.0086830680173661 0
SLC29A1-206 SLC29A1 Q99808 Equilibrative nucleoside transporter 1 chr6 GO:0006805 Not Cancer Driver No 38 0.0833333333333333 27 3 0.006578947368421 0
SLC29A3-201 SLC29A3 Q9BZD2 Equilibrative nucleoside transporter 3 chr10 GO:0006805 Not Cancer Driver No 55 0.1157894736842105 25 2 0.0042105263157894 7
SLCO1A2-217 SLCO1A2 P46721 Solute carrier organic anion transporter family member 1A2 chr12 GO:0006805 Not Cancer Driver No 119 0.1776119402985074 30 3 0.0044776119402985 0
SLCO1B1-201 SLCO1B1 Q9Y6L6 Solute carrier organic anion transporter family member 1B1 chr12 GO:0006805 Not Cancer Driver No 143 0.2069464544138929 33 3 0.004341534008683 0
SLCO1B3-202 SLCO1B3 Q9NPD5 Solute carrier organic anion transporter family member 1B3 chr12 GO:0006805 Not Cancer Driver No 167 0.2378917378917379 35 5 0.0071225071225071 0
SLCO2B1-201 SLCO2B1 O94956 Solute carrier organic anion transporter family member 2B1 chr11 GO:0006805 Not Cancer Driver No 87 0.1227080394922426 99 12 0.0169252468265162 0
SMOX-202 SMOX Q9NWM0 Spermine oxidase chr20 GO:0006805 Not Cancer Driver No 58 0.1045045045045045 165 17 0.0306306306306306 0
SULT1A1-201 SULT1A1 P50225 Sulfotransferase 1A1 chr16 GO:0006805 Not Cancer Driver No 52 0.1762711864406779 15 2 0.0067796610169491 0
SULT1A2-201 SULT1A2 P50226 Sulfotransferase 1A2 chr16 GO:0006805 Not Cancer Driver No 34 0.1152542372881356 3 0 0.0 0
SULT1A3-201 SULT1A3 P0DMM9 Sulfotransferase 1A3 chr16 GO:0006805 Not Cancer Driver No 0 0.0 32 0 0.0 0
SULT1A4-201 SULT1A3 P0DMM9 Sulfotransferase 1A3 chr16 GO:0006805 Not Cancer Driver No 0 0.0 32 0 0.0 0
SULT1B1-201 SULT1B1 O43704 Sulfotransferase 1B1 chr4 GO:0006805 Not Cancer Driver No 59 0.1993243243243243 15 6 0.0202702702702702 0
SULT1C3-201 SULT1C3 Q6IMI6 Sulfotransferase 1C3 chr2 GO:0006805 Not Cancer Driver No 61 0.2006578947368421 14 4 0.0131578947368421 0
SULT1C4-201 SULT1C4 O75897 Sulfotransferase 1C4 chr2 GO:0006805 Not Cancer Driver No 39 0.1291390728476821 22 4 0.0132450331125827 0
SULT2A1-201 SULT2A1 Q06520 Sulfotransferase 2A1 chr19 GO:0006805 Not Cancer Driver No 39 0.1368421052631579 0 0 0.0 0
TPMT-201 TPMT P51580 Thiopurine S-methyltransferase chr6 GO:0006805 Not Cancer Driver No 19 0.0775510204081632 13 0 0.0 0
UGT1A1-201 UGT1A1 P22309 UDP-glucuronosyltransferase 1A1 chr2 GO:0006805 Not Cancer Driver No 38 0.0712945590994371 11 0 0.0 53
UGT1A10-201 UGT1A10 Q9HAW8 UDP-glucuronosyltransferase 1A10 chr2 GO:0006805 Not Cancer Driver No 92 0.1735849056603773 11 0 0.0 0
UGT1A3-201 UGT1A3 P35503 UDP-glucuronosyltransferase 1A3 chr2 GO:0006805 Not Cancer Driver No 80 0.149812734082397 11 0 0.0 0
UGT1A6-201 UGT1A6 P19224 UDP-glucuronosyltransferase 1-6 chr2 GO:0006805 Not Cancer Driver No 77 0.1447368421052631 11 0 0.0 0
UGT1A7-201 UGT1A7 Q9HAW7 UDP-glucuronosyltransferase 1A7 chr2 GO:0006805 Not Cancer Driver No 79 0.1490566037735849 11 0 0.0 0
UGT1A9-201 UGT1A9 O60656 UDP-glucuronosyltransferase 1A9 chr2 GO:0006805 Not Cancer Driver No 83 0.1566037735849056 11 0 0.0 0
UGT2B11-201 UGT2B11 O75310 UDP-glucuronosyltransferase 2B11 chr4 GO:0006805 Not Cancer Driver No 106 0.2003780718336484 5 0 0.0 0
UGT2B15-201 UGT2B15 P54855 UDP-glucuronosyltransferase 2B15 chr4 GO:0006805 Not Cancer Driver No 102 0.1924528301886792 12 3 0.0056603773584905 0
UGT2B17-201 UGT2B17 O75795 UDP-glucuronosyltransferase 2B17 chr4 GO:0006805 Compendium Yes 89 0.1679245283018867 12 1 0.0018867924528301 0
UGT2B7-201 UGT2B7 P16662 UDP-glucuronosyltransferase 2B7 chr4 GO:0006805 Not Cancer Driver No 89 0.1682419659735349 6 0 0.0 0
VKORC1-205 VKORC1 Q9BQB6 Vitamin K epoxide reductase complex subunit 1 chr16 GO:0006805 Not Cancer Driver No 11 0.0674846625766871 3 0 0.0 15