Total number of protein in "GO:0006919" GO term: 65
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACER2-201 | ACER2 | Q5QJU3 | Alkaline ceramidase 2 | chr9 | GO:0006919 | Not Cancer Driver | No | 24 | 0.0872727272727272 | 0 | 0 | 0.0 | 0 |
| AIFM1-201 | AIFM1 | O95831 | Apoptosis-inducing factor 1, mitochondrial | chrX | GO:0006919 | Not Cancer Driver | No | 61 | 0.099510603588907 | 166 | 20 | 0.032626427406199 | 10 |
| ANP32B-201 | ANP32B | Q92688 | Acidic leucine-rich nuclear phosphoprotein 32 family member B | chr9 | GO:0006919 | Not Cancer Driver | No | 8 | 0.0318725099601593 | 117 | 1 | 0.0039840637450199 | 0 |
| APAF1-210 | APAF1 | O14727 | Apoptotic protease-activating factor 1 | chr12 | GO:0006919 | Not Cancer Driver | No | 91 | 0.0729166666666666 | 17 | 1 | 0.000801282051282 | 0 |
| ATP2A3-205 | ATP2A3 | Q93084 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 | chr17 | GO:0006919 | Not Cancer Driver | No | 92 | 0.0920920920920921 | 147 | 13 | 0.013013013013013 | 0 |
| BAD-201 | BAD | Q92934 | Bcl2-associated agonist of cell death | chr11 | GO:0006919 | Not Cancer Driver | No | 10 | 0.0595238095238095 | 165 | 10 | 0.0595238095238095 | 0 |
| BAX-202 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0006919 | Census | Yes | 24 | 0.125 | 39 | 2 | 0.0104166666666666 | 0 |
| BBC3-204 | BBC3 | Q96PG8 | Bcl-2-binding component 3, isoforms 3/4 | chr19 | GO:0006919 | Not Cancer Driver | No | 16 | 0.0613026819923371 | 253 | 16 | 0.0613026819923371 | 0 |
| BCL2L10-201 | BCL2L10 | Q9HD36 | Bcl-2-like protein 10 | chr15 | GO:0006919 | Not Cancer Driver | No | 6 | 0.0294117647058823 | 35 | 0 | 0.0 | 0 |
| BCL2L13-201 | BCL2L13 | Q9BXK5 | Bcl-2-like protein 13 | chr22 | GO:0006919 | Not Cancer Driver | No | 32 | 0.0659793814432989 | 291 | 18 | 0.0371134020618556 | 0 |
| BID-211 | BID | P55957 | BH3-interacting domain death agonist | chr22 | GO:0006919 | Not Cancer Driver | No | 17 | 0.0871794871794871 | 75 | 5 | 0.0256410256410256 | 0 |
| BOK-201 | BOK | Q9UMX3 | Bcl-2-related ovarian killer protein | chr2 | GO:0006919 | Not Cancer Driver | No | 5 | 0.0235849056603773 | 0 | 0 | 0.0 | 0 |
| CARD8-231 | CARD8 | Q9Y2G2 | Caspase recruitment domain-containing protein 8 | chr19 | GO:0006919 | Not Cancer Driver | No | 41 | 0.0763500931098696 | 130 | 5 | 0.0093109869646182 | 1 |
| CASP10-201 | CASP10 | Q92851 | Caspase-10 | chr2 | GO:0006919 | Not Cancer Driver | No | 37 | 0.0710172744721689 | 126 | 9 | 0.0172744721689059 | 3 |
| CASP2-201 | CASP2 | P42575 | Caspase-2 | chr7 | GO:0006919 | Not Cancer Driver | No | 49 | 0.1084070796460177 | 42 | 11 | 0.0243362831858407 | 0 |
| CASP8-218 | CASP8 | Q14790 | Caspase-8 | chr2 | GO:0006919 | Census, Compendium | Yes | 116 | 0.2421711899791231 | 106 | 11 | 0.022964509394572 | 1 |
| CASP8AP2-205 | CASP8AP2 | Q9UKL3 | CASP8-associated protein 2 | chr6 | GO:0006919 | Not Cancer Driver | No | 0 | 0.0 | 1508 | 0 | 0.0 | 0 |
| CASP9-201 | CASP9 | P55211 | Caspase-9 | chr1 | GO:0006919 | Census | Yes | 26 | 0.0625 | 71 | 7 | 0.016826923076923 | 0 |
| COL4A3-202 | COL4A3 | Q01955 | Collagen alpha-3(IV) chain | chr2 | GO:0006919 | Not Cancer Driver | No | 58 | 0.0347305389221556 | 1435 | 36 | 0.0215568862275449 | 13 |
| CRADD-201 | CRADD | P78560 | Death domain-containing protein CRADD | chr12 | GO:0006919 | Not Cancer Driver | No | 30 | 0.1507537688442211 | 45 | 4 | 0.0201005025125628 | 1 |
| DAP-201 | DAP | P51397 | Death-associated protein 1 | chr5 | GO:0006919 | Not Cancer Driver | No | 8 | 0.0784313725490196 | 102 | 8 | 0.0784313725490196 | 0 |
| DIABLO-207 | DIABLO | Q9NR28 | Diablo IAP-binding mitochondrial protein | chr12 | GO:0006919 | Not Cancer Driver | No | 20 | 0.0836820083682008 | 54 | 2 | 0.00836820083682 | 1 |
| DLC1-201 | DLC1 | Q96QB1 | Rho GTPase-activating protein 7 | chr8 | GO:0006919 | Not Cancer Driver | No | 237 | 0.1551047120418848 | 928 | 169 | 0.1106020942408377 | 0 |
| EGLN3-201 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | GO:0006919 | Not Cancer Driver | No | 21 | 0.0878661087866108 | 13 | 0 | 0.0 | 0 |
| EIF2AK3-201 | EIF2AK3 | Q9NZJ5 | Eukaryotic translation initiation factor 2-alpha kinase 3 | chr2 | GO:0006919 | Not Cancer Driver | No | 102 | 0.0913978494623656 | 411 | 37 | 0.0331541218637992 | 1 |
| F2R-201 | F2R | P25116 | Proteinase-activated receptor 1 | chr5 | GO:0006919 | Not Cancer Driver | No | 55 | 0.1294117647058823 | 19 | 2 | 0.0047058823529411 | 0 |
| F3-201 | F3 | P13726 | Tissue factor | chr1 | GO:0006919 | Not Cancer Driver | No | 18 | 0.0610169491525423 | 61 | 4 | 0.0135593220338983 | 0 |
| FAM162A-203 | FAM162A | Q96A26 | Protein FAM162A | chr3 | GO:0006919 | Not Cancer Driver | No | 10 | 0.0649350649350649 | 53 | 4 | 0.0259740259740259 | 0 |
| FASLG-202 | FASLG | P48023 | Tumor necrosis factor ligand superfamily member 6 | chr1 | GO:0006919 | Not Cancer Driver | No | 51 | 0.1814946619217081 | 94 | 15 | 0.0533807829181494 | 1 |
| HIP1-201 | HIP1 | O00291 | Huntingtin-interacting protein 1 | chr7 | GO:0006919 | Census, Compendium | Yes | 118 | 0.1137897782063645 | 514 | 60 | 0.0578592092574734 | 0 |
| HIP1R-201 | HIP1R | O75146 | Huntingtin-interacting protein 1-related protein | chr12 | GO:0006919 | Not Cancer Driver | No | 73 | 0.0683520599250936 | 527 | 30 | 0.0280898876404494 | 0 |
| HSPD1-202 | HSPD1 | P10809 | 60 kDa heat shock protein, mitochondrial | chr2 | GO:0006919 | Not Cancer Driver | No | 45 | 0.0785340314136125 | 83 | 1 | 0.0017452006980802 | 2 |
| HSPE1-201 | HSPE1 | P61604 | 10 kDa heat shock protein, mitochondrial | chr2 | GO:0006919 | Not Cancer Driver | No | 6 | 0.0588235294117647 | 3 | 0 | 0.0 | 0 |
| IFT57-201 | IFT57 | Q9NWB7 | Intraflagellar transport protein 57 homolog | chr3 | GO:0006919 | Not Cancer Driver | No | 36 | 0.0839160839160839 | 219 | 18 | 0.0419580419580419 | 0 |
| JAK2-201 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | GO:0006919 | Census, Compendium | Yes | 81 | 0.0715547703180212 | 59 | 4 | 0.0035335689045936 | 4 |
| KHDC1-202 | KHDC1 | Q4VXA5 | KH homology domain-containing protein 1 | chr6 | GO:0006919 | Not Cancer Driver | No | 33 | 0.1392405063291139 | 23 | 2 | 0.0084388185654008 | 0 |
| KHDC1L-201 | KHDC1L | Q5JSQ8 | Putative KHDC1-like protein | chr6 | GO:0006919 | Not Cancer Driver | No | 15 | 0.1171875 | 9 | 1 | 0.0078125 | 0 |
| LAPTM5-201 | LAPTM5 | Q13571 | Lysosomal-associated transmembrane protein 5 | chr1 | GO:0006919 | Not Cancer Driver | No | 34 | 0.1297709923664122 | 16 | 4 | 0.015267175572519 | 0 |
| LCK-202 | LCK | P06239 | Tyrosine-protein kinase Lck | chr1 | GO:0006919 | Census | Yes | 76 | 0.1493123772102161 | 95 | 12 | 0.0235756385068762 | 1 |
| MAPT-212 | MAPT | P10636 | Microtubule-associated protein tau | chr17 | GO:0006919 | Not Cancer Driver | No | 100 | 0.1319261213720316 | 750 | 99 | 0.1306068601583113 | 17 |
| MTCH1-202 | MTCH1 | Q9NZJ7 | Mitochondrial carrier homolog 1 | chr6 | GO:0006919 | Not Cancer Driver | No | 21 | 0.0539845758354755 | 102 | 1 | 0.0025706940874035 | 0 |
| MUL1-201 | MUL1 | Q969V5 | Mitochondrial ubiquitin ligase activator of NFKB 1 | chr1 | GO:0006919 | Not Cancer Driver | No | 29 | 0.0823863636363636 | 16 | 2 | 0.0056818181818181 | 0 |
| NGFR-201 | NGFR | P08138 | Tumor necrosis factor receptor superfamily member 16 | chr17 | GO:0006919 | Not Cancer Driver | No | 46 | 0.1077283372365339 | 174 | 23 | 0.0538641686182669 | 0 |
| NKX3-1-201 | NKX3-1 | Q99801 | Homeobox protein Nkx-3.1 | chr8 | GO:0006919 | Not Cancer Driver | No | 26 | 0.1111111111111111 | 175 | 12 | 0.0512820512820512 | 0 |
| NLRC4-203 | NLRC4 | Q9NPP4 | NLR family CARD domain-containing protein 4 | chr2 | GO:0006919 | Not Cancer Driver | No | 135 | 0.1318359375 | 15 | 1 | 0.0009765625 | 3 |
| NLRP1-208 | NLRP1 | Q9C000 | NACHT, LRR and PYD domains-containing protein 1 | chr17 | GO:0006919 | Not Cancer Driver | No | 169 | 0.1147318397827562 | 341 | 45 | 0.0305498981670061 | 6 |
| NLRP12-201 | NLRP12 | P59046 | NACHT, LRR and PYD domains-containing protein 12 | chr19 | GO:0006919 | Not Cancer Driver | No | 258 | 0.2431668237511781 | 115 | 37 | 0.0348727615457115 | 0 |
| NOD1-201 | NOD1 | Q9Y239 | Nucleotide-binding oligomerization domain-containing protein 1 | chr7 | GO:0006919 | Not Cancer Driver | No | 98 | 0.1028331584470094 | 39 | 4 | 0.0041972717733473 | 0 |
| PDCD2-208 | PDCD2 | Q16342 | Programmed cell death protein 2 | chr6 | GO:0006919 | Not Cancer Driver | No | 25 | 0.0726744186046511 | 42 | 6 | 0.0174418604651162 | 0 |
| PIDD1-201 | PIDD1 | Q9HB75 | p53-induced death domain-containing protein 1 | chr11 | GO:0006919 | Not Cancer Driver | No | 72 | 0.0791208791208791 | 140 | 9 | 0.0098901098901098 | 2 |
| PPARG-201 | PPARG | P37231 | Peroxisome proliferator-activated receptor gamma | chr3 | GO:0006919 | Census | Yes | 60 | 0.1188118811881188 | 44 | 3 | 0.0059405940594059 | 3 |
| PYCARD-201 | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:0006919 | Not Cancer Driver | No | 12 | 0.0615384615384615 | 39 | 4 | 0.0205128205128205 | 0 |
| RACK1-227 | RACK1 | P63244 | Small ribosomal subunit protein RACK1 | chr5 | GO:0006919 | Not Cancer Driver | No | 27 | 0.085173501577287 | 13 | 0 | 0.0 | 0 |
| ROBO1-202 | ROBO1 | Q9Y6N7 | Roundabout homolog 1 | chr3 | GO:0006919 | Not Cancer Driver | No | 245 | 0.1483949121744397 | 1125 | 158 | 0.0956995760145366 | 0 |
| RPS27L-201 | RPS27L | Q71UM5 | Ribosomal protein eS27-like | chr15 | GO:0006919 | Not Cancer Driver | No | 3 | 0.0357142857142857 | 22 | 1 | 0.0119047619047619 | 0 |
| S100A8-202 | S100A8 | P05109 | Protein S100-A8 | chr1 | GO:0006919 | Not Cancer Driver | No | 17 | 0.1827956989247312 | 8 | 4 | 0.043010752688172 | 0 |
| S100A9-201 | S100A9 | P06702 | Protein S100-A9 | chr1 | GO:0006919 | Not Cancer Driver | No | 16 | 0.1403508771929824 | 76 | 8 | 0.0701754385964912 | 0 |
| SENP1-204 | SENP1 | Q9P0U3 | Sentrin-specific protease 1 | chr12 | GO:0006919 | Not Cancer Driver | No | 42 | 0.0652173913043478 | 355 | 31 | 0.0481366459627329 | 0 |
| SLC22A2-202 | SLC22A2 | O15244 | Solute carrier family 22 member 2 | chr6 | GO:0006919 | Not Cancer Driver | No | 94 | 0.1693693693693693 | 32 | 10 | 0.018018018018018 | 0 |
| SMAD3-201 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0006919 | Census, Compendium | Yes | 80 | 0.188235294117647 | 113 | 15 | 0.0352941176470588 | 5 |
| SNCA-205 | SNCA | P37840 | Alpha-synuclein | chr4 | GO:0006919 | Not Cancer Driver | No | 15 | 0.1071428571428571 | 107 | 10 | 0.0714285714285714 | 5 |
| TNF-208 | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0006919 | Not Cancer Driver | No | 22 | 0.0944206008583691 | 45 | 2 | 0.0085836909871244 | 0 |
| TNFSF15-202 | TNFSF15 | O95150 | Tumor necrosis factor ligand superfamily member 15 | chr9 | GO:0006919 | Not Cancer Driver | No | 31 | 0.1235059760956175 | 49 | 10 | 0.0398406374501992 | 0 |
| VCP-201 | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | GO:0006919 | Not Cancer Driver | No | 74 | 0.0918114143920595 | 186 | 14 | 0.0173697270471464 | 12 |
| XDH-201 | XDH | P47989 | Xanthine dehydrogenase/oxidase | chr2 | GO:0006919 | Not Cancer Driver | No | 227 | 0.1702925731432858 | 136 | 20 | 0.0150037509377344 | 1 |