Total number of protein in "GO:0006959" GO term: 60
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AIRE-201 | AIRE | O43918 | Autoimmune regulator | chr21 | GO:0006959 | Not Cancer Driver | No | 53 | 0.0972477064220183 | 340 | 34 | 0.0623853211009174 | 18 |
ALOX5-201 | ALOX5 | P09917 | Polyunsaturated fatty acid 5-lipoxygenase | chr10 | GO:0006959 | Not Cancer Driver | No | 100 | 0.1483679525222551 | 16 | 1 | 0.0014836795252225 | 0 |
BCL2-201 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:0006959 | Census, Compendium | Yes | 21 | 0.0878661087866108 | 73 | 5 | 0.0209205020920502 | 0 |
BLNK-201 | BLNK | Q8WV28 | B-cell linker protein | chr10 | GO:0006959 | Not Cancer Driver | No | 54 | 0.1184210526315789 | 380 | 48 | 0.1052631578947368 | 0 |
BMI1-201 | BMI1 | P35226 | Polycomb complex protein BMI-1 | chr10 | GO:0006959 | Not Cancer Driver | No | 34 | 0.1042944785276073 | 150 | 23 | 0.0705521472392638 | 0 |
BST1-201 | BST1 | Q10588 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 | chr4 | GO:0006959 | Not Cancer Driver | No | 29 | 0.0911949685534591 | 11 | 0 | 0.0 | 0 |
CCL2-201 | CCL2 | P13500 | C-C motif chemokine 2 | chr17 | GO:0006959 | Not Cancer Driver | No | 19 | 0.1919191919191919 | 15 | 5 | 0.0505050505050505 | 0 |
CCR2-201 | CCR2 | P41597 | C-C chemokine receptor type 2 | chr3 | GO:0006959 | Not Cancer Driver | No | 56 | 0.1497326203208556 | 23 | 2 | 0.0053475935828877 | 0 |
CCR6-201 | CCR6 | P51684 | C-C chemokine receptor type 6 | chr6 | GO:0006959 | Not Cancer Driver | No | 46 | 0.1229946524064171 | 13 | 2 | 0.0053475935828877 | 0 |
CD28-201 | CD28 | P10747 | T-cell-specific surface glycoprotein CD28 | chr2 | GO:0006959 | Census | Yes | 26 | 0.1181818181818181 | 18 | 6 | 0.0272727272727272 | 0 |
CD83-201 | CD83 | Q01151 | CD83 antigen | chr6 | GO:0006959 | Not Cancer Driver | No | 23 | 0.1121951219512195 | 49 | 8 | 0.0390243902439024 | 0 |
EBI3-201 | EBI3 | Q14213 | Interleukin-27 subunit beta | chr19 | GO:0006959 | Not Cancer Driver | No | 19 | 0.0829694323144104 | 10 | 0 | 0.0 | 0 |
FOXJ1-201 | FOXJ1 | Q92949 | Forkhead box protein J1 | chr17 | GO:0006959 | Not Cancer Driver | No | 22 | 0.0522565320665083 | 280 | 17 | 0.0403800475059382 | 0 |
GATA3-201 | GATA3 | P23771 | Trans-acting T-cell-specific transcription factor GATA-3 | chr10 | GO:0006959 | Census, Compendium | Yes | 99 | 0.2234762979683973 | 368 | 79 | 0.1783295711060948 | 2 |
GPI-201 | GPI | P06744 | Glucose-6-phosphate isomerase | chr19 | GO:0006959 | Not Cancer Driver | No | 56 | 0.1003584229390681 | 73 | 10 | 0.017921146953405 | 23 |
GPR183-201 | GPR183 | P32249 | G-protein coupled receptor 183 | chr13 | GO:0006959 | Not Cancer Driver | No | 35 | 0.0969529085872576 | 25 | 3 | 0.0083102493074792 | 0 |
HLA-DQB1-205 | HLA-DQB1 | P01920 | HLA class II histocompatibility antigen, DQ beta 1 chain | chr6 | GO:0006959 | Not Cancer Driver | No | 17 | 0.0651340996168582 | 25 | 1 | 0.003831417624521 | 0 |
HLA-DRB1-201 | HLA-DRB1 | P01911 | HLA class II histocompatibility antigen, DRB1 beta chain | chr6 | GO:0006959 | Not Cancer Driver | No | 11 | 0.0413533834586466 | 12 | 0 | 0.0 | 0 |
IFNA1-201 | IFNA13 | P01562 | Interferon alpha-1/13 | chr9 | GO:0006959 | Not Cancer Driver | No | 23 | 0.1216931216931216 | 2 | 1 | 0.0052910052910052 | 0 |
IFNA10-201 | IFNA10 | P01566 | Interferon alpha-10 | chr9 | GO:0006959 | Not Cancer Driver | No | 25 | 0.1322751322751322 | 1 | 0 | 0.0 | 0 |
IFNA13-202 | IFNA13 | P01562 | Interferon alpha-1/13 | chr9 | GO:0006959 | Not Cancer Driver | No | 29 | 0.1526315789473684 | 2 | 0 | 0.0 | 0 |
IFNA14-201 | IFNA14 | P01570 | Interferon alpha-14 | chr9 | GO:0006959 | Not Cancer Driver | No | 27 | 0.1428571428571428 | 1 | 1 | 0.0052910052910052 | 0 |
IFNA16-201 | IFNA16 | P05015 | Interferon alpha-16 | chr9 | GO:0006959 | Not Cancer Driver | No | 51 | 0.2698412698412698 | 1 | 0 | 0.0 | 0 |
IFNA17-201 | IFNA17 | P01571 | Interferon alpha-17 | chr9 | GO:0006959 | Not Cancer Driver | No | 29 | 0.1534391534391534 | 0 | 0 | 0.0 | 0 |
IFNA2-201 | IFNA2 | P01563 | Interferon alpha-2 | chr9 | GO:0006959 | Not Cancer Driver | No | 24 | 0.1276595744680851 | 2 | 0 | 0.0 | 0 |
IFNA21-201 | IFNA21 | P01568 | Interferon alpha-21 | chr9 | GO:0006959 | Not Cancer Driver | No | 23 | 0.1216931216931216 | 0 | 0 | 0.0 | 0 |
IFNA4-201 | IFNA4 | P05014 | Interferon alpha-4 | chr9 | GO:0006959 | Not Cancer Driver | No | 30 | 0.1587301587301587 | 1 | 0 | 0.0 | 0 |
IFNA5-201 | IFNA5 | P01569 | Interferon alpha-5 | chr9 | GO:0006959 | Not Cancer Driver | No | 27 | 0.1428571428571428 | 1 | 0 | 0.0 | 0 |
IFNA6-202 | IFNA6 | P05013 | Interferon alpha-6 | chr9 | GO:0006959 | Not Cancer Driver | No | 21 | 0.1111111111111111 | 4 | 0 | 0.0 | 0 |
IFNA7-201 | IFNA7 | P01567 | Interferon alpha-7 | chr9 | GO:0006959 | Not Cancer Driver | No | 33 | 0.1746031746031746 | 1 | 1 | 0.0052910052910052 | 0 |
IFNA8-201 | IFNA8 | P32881 | Interferon alpha-8 | chr9 | GO:0006959 | Not Cancer Driver | No | 33 | 0.1746031746031746 | 0 | 0 | 0.0 | 0 |
IFNB1-201 | IFNB1 | P01574 | Interferon beta | chr9 | GO:0006959 | Not Cancer Driver | No | 29 | 0.1550802139037433 | 0 | 0 | 0.0 | 0 |
IFNE-201 | IFNE | Q86WN2 | Interferon epsilon | chr9 | GO:0006959 | Not Cancer Driver | No | 22 | 0.1057692307692307 | 17 | 3 | 0.0144230769230769 | 0 |
IFNG-201 | IFNG | P01579 | Interferon gamma | chr12 | GO:0006959 | Not Cancer Driver | No | 34 | 0.2048192771084337 | 23 | 3 | 0.0180722891566265 | 0 |
IFNK-201 | IFNK | Q9P0W0 | Interferon kappa | chr9 | GO:0006959 | Not Cancer Driver | No | 13 | 0.0628019323671497 | 24 | 0 | 0.0 | 0 |
IFNW1-201 | IFNW1 | P05000 | Interferon omega-1 | chr9 | GO:0006959 | Not Cancer Driver | No | 28 | 0.1435897435897435 | 10 | 3 | 0.0153846153846153 | 0 |
IL6-201 | IL6 | P05231 | Interleukin-6 | chr7 | GO:0006959 | Not Cancer Driver | No | 32 | 0.1509433962264151 | 58 | 6 | 0.0283018867924528 | 0 |
IL7-201 | IL7 | P13232 | Interleukin-7 | chr8 | GO:0006959 | Not Cancer Driver | No | 19 | 0.1073446327683615 | 19 | 3 | 0.0169491525423728 | 0 |
JCHAIN-201 | JCHAIN | P01591 | Immunoglobulin J chain | chr4 | GO:0006959 | Not Cancer Driver | No | 25 | 0.1572327044025157 | 9 | 2 | 0.0125786163522012 | 0 |
LTA-213 | LTA | P01374 | Lymphotoxin-alpha | chr6 | GO:0006959 | Not Cancer Driver | No | 32 | 0.1560975609756097 | 20 | 4 | 0.0195121951219512 | 0 |
LTF-201 | LTF | P02788 | Lactotransferrin | chr3 | GO:0006959 | Not Cancer Driver | No | 90 | 0.1267605633802817 | 21 | 3 | 0.004225352112676 | 0 |
MEF2C-209 | MEF2C | Q06413 | Myocyte-specific enhancer factor 2C | chr5 | GO:0006959 | Not Cancer Driver | No | 54 | 0.1141649048625792 | 408 | 51 | 0.1078224101479915 | 2 |
MS4A1-201 | MS4A1 | P11836 | B-lymphocyte antigen CD20 | chr11 | GO:0006959 | Not Cancer Driver | No | 58 | 0.1952861952861952 | 83 | 18 | 0.0606060606060606 | 0 |
NOTCH1-204 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | GO:0006959 | Census, Compendium | Yes | 312 | 0.1221135029354207 | 690 | 71 | 0.0277886497064579 | 3 |
NOTCH2-201 | NOTCH2 | Q04721 | Neurogenic locus notch homolog protein 2 | chr1 | GO:0006959 | Census, Compendium | Yes | 191 | 0.0772966410360178 | 631 | 61 | 0.0246863617968433 | 1 |
PDCD1-201 | PDCD1 | Q15116 | Programmed cell death protein 1 | chr2 | GO:0006959 | Not Cancer Driver | No | 45 | 0.15625 | 141 | 31 | 0.1076388888888889 | 0 |
POU2AF1-201 | POU2AF1 | Q16633 | POU domain class 2-associating factor 1 | chr11 | GO:0006959 | Census | Yes | 48 | 0.1875 | 181 | 36 | 0.140625 | 0 |
POU2F2-204 | POU2F2 | P09086 | POU domain, class 2, transcription factor 2 | chr19 | GO:0006959 | Compendium | Yes | 66 | 0.1377870563674321 | 387 | 57 | 0.1189979123173277 | 0 |
PSMB10-201 | PSMB10 | P40306 | Proteasome subunit beta type-10 | chr16 | GO:0006959 | Not Cancer Driver | No | 15 | 0.0549450549450549 | 36 | 4 | 0.0146520146520146 | 0 |
RBPJ-206 | RBPJ | Q06330 | Recombining binding protein suppressor of hairless | chr4 | GO:0006959 | Not Cancer Driver | No | 32 | 0.064 | 151 | 10 | 0.02 | 2 |
SH2D1A-202 | SH2D1A | O60880 | SH2 domain-containing protein 1A | chrX | GO:0006959 | Not Cancer Driver | No | 28 | 0.21875 | 24 | 6 | 0.046875 | 19 |
ST6GAL1-201 | ST6GAL1 | P15907 | Beta-galactoside alpha-2,6-sialyltransferase 1 | chr3 | GO:0006959 | Not Cancer Driver | No | 39 | 0.0960591133004926 | 34 | 6 | 0.0147783251231527 | 0 |
TFE3-201 | TFE3 | P19532 | Transcription factor E3 | chrX | GO:0006959 | Census | Yes | 44 | 0.0765217391304347 | 526 | 41 | 0.0713043478260869 | 9 |
TFEB-204 | TFEB | P19484 | Transcription factor EB | chr6 | GO:0006959 | Census | Yes | 46 | 0.0966386554621848 | 431 | 41 | 0.0861344537815126 | 0 |
TNF-208 | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0006959 | Not Cancer Driver | No | 22 | 0.0944206008583691 | 45 | 2 | 0.0085836909871244 | 0 |
TNFRSF21-201 | TNFRSF21 | O75509 | Tumor necrosis factor receptor superfamily member 21 | chr6 | GO:0006959 | Not Cancer Driver | No | 72 | 0.1099236641221374 | 280 | 38 | 0.0580152671755725 | 0 |
TRAF3IP2-201 | TRAF3IP2 | O43734 | E3 ubiquitin ligase TRAF3IP2 | chr6 | GO:0006959 | Not Cancer Driver | No | 47 | 0.0818815331010452 | 413 | 34 | 0.0592334494773519 | 2 |
TREM1-201 | TREM1 | Q9NP99 | Triggering receptor expressed on myeloid cells 1 | chr6 | GO:0006959 | Not Cancer Driver | No | 36 | 0.1538461538461538 | 63 | 5 | 0.0213675213675213 | 0 |
TREM2-202 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:0006959 | Not Cancer Driver | No | 31 | 0.1347826086956521 | 27 | 2 | 0.008695652173913 | 1 |
YTHDF2-201 | YTHDF2 | Q9Y5A9 | YTH domain-containing family protein 2 | chr1 | GO:0006959 | Not Cancer Driver | No | 48 | 0.082901554404145 | 376 | 29 | 0.0500863557858376 | 0 |