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Total number of protein in "GO:0006979" GO term:  113

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCB11-206 ABCB11 O95342 Bile salt export pump chr2 GO:0006979 Not Cancer Driver No 167 0.1264193792581378 125 20 0.0151400454201362 21
ABL1-201 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0006979 Census, Compendium Yes 106 0.0938053097345132 609 53 0.0469026548672566 2
AKT1-218 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0006979 Census, Compendium Yes 99 0.20625 158 19 0.0395833333333333 4
ALAD-201 ALAD P13716 Delta-aminolevulinic acid dehydratase chr9 GO:0006979 Not Cancer Driver No 35 0.106060606060606 13 2 0.006060606060606 5
ALDH3B1-201 ALDH3B1 P43353 Aldehyde dehydrogenase family 3 member B1 chr11 GO:0006979 Not Cancer Driver No 28 0.0598290598290598 23 5 0.0106837606837606 0
ALS2-201 ALS2 Q96Q42 Alsin chr2 GO:0006979 Not Cancer Driver No 133 0.08026554013277 354 24 0.0144840072420036 0
ANGPTL7-201 ANGPTL7 O43827 Angiopoietin-related protein 7 chr1 GO:0006979 Not Cancer Driver No 28 0.0809248554913294 33 6 0.0173410404624277 0
APP-201 APP P05067 Amyloid-beta precursor protein chr21 GO:0006979 Not Cancer Driver No 94 0.122077922077922 419 52 0.0675324675324675 12
ATOX1-201 ATOX1 O00244 Copper transport protein ATOX1 chr5 GO:0006979 Not Cancer Driver No 2 0.0294117647058823 0 0 0.0 0
BANF1-201 BANF1 O75531 Barrier-to-autointegration factor chr11 GO:0006979 Not Cancer Driver No 5 0.0561797752808988 11 2 0.0224719101123595 1
BTG1-201 BTG1 P62324 Protein BTG1 chr12 GO:0006979 Census, Compendium Yes 22 0.1286549707602339 19 0 0.0 0
C19orf12-201 C19orf12 Q9NSK7 Protein C19orf12 chr19 GO:0006979 Not Cancer Driver No 15 0.1063829787234042 0 0 0.0 14
CHRNA4-201 CHRNA4 P43681 Neuronal acetylcholine receptor subunit alpha-4 chr20 GO:0006979 Not Cancer Driver No 112 0.1786283891547049 188 26 0.0414673046251993 1
COMT-202 COMT P21964 Catechol O-methyltransferase chr22 GO:0006979 Not Cancer Driver No 16 0.059040590405904 5 0 0.0 0
CYB5B-201 CYB5B O43169 Cytochrome b5 type B chr16 GO:0006979 Not Cancer Driver No 16 0.1066666666666666 59 2 0.0133333333333333 0
CYGB-201 CYGB Q8WWM9 Cytoglobin chr17 GO:0006979 Not Cancer Driver No 21 0.1105263157894736 48 4 0.0210526315789473 0
DGKK-201 DGKK Q5KSL6 Diacylglycerol kinase kappa chrX GO:0006979 Not Cancer Driver No 0 0.0 383 0 0.0 0
DUOX1-202 DUOX1 Q9NRD9 Dual oxidase 1 chr15 GO:0006979 Not Cancer Driver No 118 0.0760799484203739 161 13 0.008381689232753 0
DUOX2-205 DUOX2 Q9NRD8 Dual oxidase 2 chr15 GO:0006979 Not Cancer Driver No 182 0.1175710594315245 186 19 0.0122739018087855 3
EPAS1-201 EPAS1 Q99814 Endothelial PAS domain-containing protein 1 chr2 GO:0006979 Census, Compendium Yes 109 0.125287356321839 451 54 0.0620689655172413 4
EPX-201 EPX P11678 Eosinophil peroxidase chr17 GO:0006979 Not Cancer Driver No 107 0.1496503496503496 55 5 0.0069930069930069 1
ERCC1-202 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0006979 Not Cancer Driver No 36 0.1212121212121212 107 14 0.0471380471380471 1
ERCC2-204 ERCC2 P18074 General transcription and DNA repair factor IIH helicase subunit XPD chr19 GO:0006979 Census, Compendium Yes 103 0.1355263157894737 5 0 0.0 30
ERCC3-201 ERCC3 P19447 General transcription and DNA repair factor IIH helicase subunit XPB chr2 GO:0006979 Census, Compendium Yes 67 0.0856777493606138 208 14 0.0179028132992327 2
ERCC6-201 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0006979 Not Cancer Driver No 142 0.0951105157401205 837 82 0.0549229738780977 9
ERCC8-218 ERCC8 Q13216 DNA excision repair protein ERCC-8 chr5 GO:0006979 Not Cancer Driver No 17 0.0429292929292929 55 7 0.0176767676767676 6
ERO1A-201 ERO1A Q96HE7 ERO1-like protein alpha chr14 GO:0006979 Not Cancer Driver No 34 0.0726495726495726 33 4 0.0085470085470085 0
ETFDH-206 ETFDH Q16134 Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial chr4 GO:0006979 Not Cancer Driver No 41 0.06645056726094 64 3 0.0048622366288492 9
FGF8-202 FGF8 P55075 Fibroblast growth factor 8 chr10 GO:0006979 Not Cancer Driver No 27 0.1158798283261802 79 8 0.0343347639484978 6
FOXO4-202 FOXO4 P98177 Forkhead box protein O4 chrX GO:0006979 Census Yes 56 0.1108910891089108 441 45 0.0891089108910891 0
GCLC-214 GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 GO:0006979 Not Cancer Driver No 55 0.086342229199372 167 15 0.0235478806907378 3
GCLM-201 GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:0006979 Not Cancer Driver No 21 0.0766423357664233 31 3 0.010948905109489 0
GPX2-201 GPX2 P18283 Glutathione peroxidase 2 chr14 GO:0006979 Not Cancer Driver No 20 0.1052631578947368 0 0 0.0 0
GPX4-201 GPX4 P36969 Phospholipid hydroperoxide glutathione peroxidase chr19 GO:0006979 Not Cancer Driver No 12 0.0609137055837563 0 0 0.0 0
GPX6-201 GPX6 P59796 Glutathione peroxidase 6 chr6 GO:0006979 Not Cancer Driver No 51 0.2307692307692307 0 0 0.0 0
GSS-228 GSS P48637 Glutathione synthetase chr20 GO:0006979 Not Cancer Driver No 44 0.0928270042194092 49 5 0.010548523206751 12
HAO1-201 HAO1 Q9UJM8 2-Hydroxyacid oxidase 1 chr20 GO:0006979 Not Cancer Driver No 87 0.2351351351351351 7 2 0.0054054054054054 0
HMOX1-201 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0006979 Not Cancer Driver No 33 0.1145833333333333 82 11 0.0381944444444444 0
HMOX2-208 HMOX2 P30519 Heme oxygenase 2 chr16 GO:0006979 Not Cancer Driver No 17 0.0537974683544303 74 5 0.0158227848101265 0
IDH1-201 IDH1 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic chr2 GO:0006979 Census, Compendium Yes 522 1.2608695652173914 37 2 0.0048309178743961 0
IPCEF1-201 IPCEF1 Q8WWN9 Interactor protein for cytohesin exchange factors 1 chr6 GO:0006979 Not Cancer Driver No 45 0.102974828375286 293 23 0.0526315789473684 0
KRT1-201 KRT1 P04264 Keratin, type II cytoskeletal 1 chr12 GO:0006979 Not Cancer Driver No 68 0.1055900621118012 429 40 0.062111801242236 15
LIAS-222 LIAS O43766 Lipoyl synthase, mitochondrial chr4 GO:0006979 Not Cancer Driver No 32 0.086021505376344 83 8 0.021505376344086 1
LPO-201 LPO P22079 Lactoperoxidase chr17 GO:0006979 Not Cancer Driver No 96 0.1348314606741573 100 12 0.0168539325842696 0
LRRK2-201 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0006979 Not Cancer Driver No 402 0.1590819153146023 91 13 0.0051444400474871 20
MAPK8-206 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0006979 Not Cancer Driver No 52 0.1217798594847775 94 9 0.0210772833723653 0
MBL2-202 MBL2 P11226 Mannose-binding protein C chr10 GO:0006979 Not Cancer Driver No 49 0.1975806451612903 124 31 0.125 0
MICB-201 MICB Q29980 MHC class I polypeptide-related sequence B chr6 GO:0006979 Not Cancer Driver No 41 0.1070496083550913 175 16 0.04177545691906 0
MMP14-201 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0006979 Not Cancer Driver No 50 0.0859106529209622 120 6 0.0103092783505154 1
MPO-201 MPO P05164 Myeloperoxidase chr17 GO:0006979 Not Cancer Driver No 127 0.1704697986577181 52 10 0.0134228187919463 3
MSRA-201 MSRA Q9UJ68 Mitochondrial peptide methionine sulfoxide reductase chr8 GO:0006979 Not Cancer Driver No 42 0.1787234042553191 81 15 0.0638297872340425 0
MSRB2-201 MSRB2 Q9Y3D2 Methionine-R-sulfoxide reductase B2, mitochondrial chr10 GO:0006979 Not Cancer Driver No 11 0.0604395604395604 66 6 0.0329670329670329 0
MSRB3-202 MSRB3 Q8IXL7 Methionine-R-sulfoxide reductase B3 chr12 GO:0006979 Not Cancer Driver No 32 0.1666666666666666 42 12 0.0625 1
MT-CO1-201 MT-CO1 P00395 Cytochrome c oxidase subunit 1 chrM GO:0006979 Not Cancer Driver No 0 0.0 0 0 0.0 4
MT-ND3-201 MT-ND3 P03897 NADH-ubiquinone oxidoreductase chain 3 chrM GO:0006979 Not Cancer Driver No 0 0.0 0 0 0.0 4
MTF1-201 MTF1 Q14872 Metal regulatory transcription factor 1 chr1 GO:0006979 Not Cancer Driver No 80 0.1062416998671978 554 56 0.0743691899070385 0
NAPRT-204 NAPRT Q6XQN6 Nicotinate phosphoribosyltransferase chr8 GO:0006979 Not Cancer Driver No 34 0.0631970260223048 98 9 0.0167286245353159 0
NCOA7-203 NCOA7 Q8NI08 Nuclear receptor coactivator 7 chr6 GO:0006979 Not Cancer Driver No 82 0.0870488322717622 538 42 0.0445859872611464 0
NDUFA12-201 NDUFA12 Q9UI09 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 chr12 GO:0006979 Not Cancer Driver No 14 0.096551724137931 31 5 0.0344827586206896 0
NDUFA6-202 NDUFA6 P56556 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 chr22 GO:0006979 Not Cancer Driver No 3 0.0234375 14 0 0.0 1
NDUFB4-201 NDUFB4 O95168 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 chr3 GO:0006979 Not Cancer Driver No 10 0.0775193798449612 20 1 0.0077519379844961 0
NDUFS2-224 NDUFS2 O75306 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial chr1 GO:0006979 Not Cancer Driver No 44 0.0950323974082073 51 4 0.0086393088552915 4
NDUFS8-201 NDUFS8 O00217 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial chr11 GO:0006979 Not Cancer Driver No 22 0.1047619047619047 37 3 0.0142857142857142 3
NEIL1-201 NEIL1 Q96FI4 Endonuclease 8-like 1 chr15 GO:0006979 Not Cancer Driver No 32 0.082051282051282 166 10 0.0256410256410256 0
NFE2L2-201 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0006979 Census, Compendium Yes 235 0.3884297520661157 402 59 0.0975206611570247 4
NQO1-201 NQO1 P15559 NAD(P)H dehydrogenase [quinone] 1 chr16 GO:0006979 Not Cancer Driver No 11 0.0401459854014598 10 0 0.0 0
NUDT1-203 NUDT1 P36639 Oxidized purine nucleoside triphosphate hydrolase chr7 GO:0006979 Not Cancer Driver No 23 0.1474358974358974 17 4 0.0256410256410256 0
OGG1-205 OGG1 O15527 N-glycosylase/DNA lyase chr3 GO:0006979 Not Cancer Driver No 26 0.0753623188405797 72 4 0.0115942028985507 0
OXR1-205 OXR1 Q8N573 Oxidation resistance protein 1 chr8 GO:0006979 Not Cancer Driver No 87 0.0995423340961098 545 56 0.0640732265446224 0
OXSR1-201 OXSR1 O95747 Serine/threonine-protein kinase OSR1 chr3 GO:0006979 Not Cancer Driver No 51 0.0967741935483871 208 22 0.0417457305502846 0
PARK7-201 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0006979 Not Cancer Driver No 8 0.0423280423280423 30 0 0.0 6
PDLIM1-201 PDLIM1 O00151 PDZ and LIM domain protein 1 chr10 GO:0006979 Not Cancer Driver No 48 0.1458966565349544 221 31 0.094224924012158 0
PINK1-201 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0006979 Not Cancer Driver No 46 0.0791738382099827 99 8 0.0137693631669535 24
PNKP-201 PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 GO:0006979 Not Cancer Driver No 46 0.0882917466410748 177 21 0.0403071017274472 4
PRDX1-202 PRDX1 Q06830 Peroxiredoxin-1 chr1 GO:0006979 Not Cancer Driver No 23 0.1155778894472361 40 7 0.0351758793969849 0
PRDX2-201 PRDX2 P32119 Peroxiredoxin-2 chr19 GO:0006979 Not Cancer Driver No 22 0.1111111111111111 30 3 0.0151515151515151 0
PRDX3-201 PRDX3 P30048 Thioredoxin-dependent peroxide reductase, mitochondrial chr10 GO:0006979 Not Cancer Driver No 17 0.06640625 23 2 0.0078125 2
PRDX4-202 PRDX4 Q13162 Peroxiredoxin-4 chrX GO:0006979 Not Cancer Driver No 31 0.1143911439114391 29 2 0.007380073800738 0
PRDX5-201 PRDX5 P30044 Peroxiredoxin-5, mitochondrial chr11 GO:0006979 Not Cancer Driver No 13 0.0607476635514018 0 0 0.0 0
PRDX6-201 PRDX6 P30041 Peroxiredoxin-6 chr1 GO:0006979 Not Cancer Driver No 32 0.1428571428571428 13 3 0.0133928571428571 0
PRKN-206 PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0006979 Not Cancer Driver No 96 0.2064516129032258 78 14 0.0301075268817204 30
PRNP-201 PRNP P04156 Major prion protein chr20 GO:0006979 Not Cancer Driver No 28 0.1106719367588932 117 8 0.0316205533596837 19
PSEN1-201 PSEN1 P49768 Presenilin-1 chr14 GO:0006979 Not Cancer Driver No 43 0.0920770877944325 134 18 0.038543897216274 69
PSIP1-203 PSIP1 O75475 PC4 and SFRS1-interacting protein chr9 GO:0006979 Census, Compendium Yes 45 0.0849056603773584 482 42 0.0792452830188679 0
PSMB5-202 PSMB5 P28074 Proteasome subunit beta type-5 chr14 GO:0006979 Not Cancer Driver No 31 0.11787072243346 9 0 0.0 0
PTGS1-202 PTGS1 P23219 Prostaglandin G/H synthase 1 chr9 GO:0006979 Not Cancer Driver No 92 0.1535893155258764 28 3 0.005008347245409 0
PTGS2-201 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0006979 Not Cancer Driver No 68 0.1125827814569536 31 4 0.0066225165562913 0
PXDN-201 PXDN Q92626 Peroxidasin homolog chr2 GO:0006979 Not Cancer Driver No 265 0.1791751183231913 307 60 0.0405679513184584 1
PXDNL-201 PXDNL A1KZ92 Probable oxidoreductase PXDNL chr8 GO:0006979 Not Cancer Driver No 453 0.3096377306903622 400 142 0.0970608339029391 0
RBPMS-204 RBPMS Q93062 RNA-binding protein with multiple splicing chr8 GO:0006979 Not Cancer Driver No 14 0.0714285714285714 87 7 0.0357142857142857 0
RCAN1-201 RCAN1 P53805 Calcipressin-1 chr21 GO:0006979 Not Cancer Driver No 20 0.0793650793650793 103 6 0.0238095238095238 0
RGS14-201 RGS14 O43566 Regulator of G-protein signaling 14 chr5 GO:0006979 Not Cancer Driver No 46 0.0812720848056537 309 27 0.0477031802120141 0
RIPK1-201 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0006979 Compendium Yes 59 0.0879284649776453 277 28 0.0417287630402384 1
RRM2B-201 RRM2B Q7LG56 Ribonucleoside-diphosphate reductase subunit M2 B chr8 GO:0006979 Not Cancer Driver No 31 0.0883190883190883 32 4 0.0113960113960113 9
SCARA3-201 SCARA3 Q6AZY7 Scavenger receptor class A member 3 chr8 GO:0006979 Not Cancer Driver No 50 0.0825082508250825 231 18 0.0297029702970297 0
SELENOK-204 SELENOK Q9Y6D0 Selenoprotein K chr3 GO:0006979 Not Cancer Driver No 4 0.0425531914893617 47 4 0.0425531914893617 0
SELENOP-214 SELENOP P49908 Selenoprotein P chr5 GO:0006979 Not Cancer Driver No 46 0.1207349081364829 155 14 0.0367454068241469 0
SGK2-203 SGK2 Q9HBY8 Serine/threonine-protein kinase Sgk2 chr20 GO:0006979 Not Cancer Driver No 72 0.1961852861035422 52 9 0.0245231607629427 0
SIRT1-201 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0006979 Not Cancer Driver No 43 0.0575635876840696 435 19 0.0254350736278447 0
SLC23A2-201 SLC23A2 Q9UGH3 Solute carrier family 23 member 2 chr20 GO:0006979 Not Cancer Driver No 67 0.103076923076923 77 4 0.0061538461538461 0
SRXN1-201 SRXN1 Q9BYN0 Sulfiredoxin-1 chr20 GO:0006979 Not Cancer Driver No 10 0.072992700729927 48 1 0.0072992700729927 0
STC2-201 STC2 O76061 Stanniocalcin-2 chr5 GO:0006979 Not Cancer Driver No 60 0.1986754966887417 112 28 0.0927152317880794 0
STK25-201 STK25 O00506 Serine/threonine-protein kinase 25 chr2 GO:0006979 Not Cancer Driver No 34 0.0798122065727699 171 13 0.0305164319248826 0
TAT-201 TAT P17735 Tyrosine aminotransferase chr16 GO:0006979 Not Cancer Driver No 75 0.1651982378854625 76 15 0.0330396475770925 1
THG1L-201 THG1L Q9NWX6 Probable tRNA(His) guanylyltransferase chr5 GO:0006979 Not Cancer Driver No 20 0.0671140939597315 22 2 0.0067114093959731 1
TLDC2-201 TLDC2 A0PJX2 TLD domain-containing protein 2 chr20 GO:0006979 Not Cancer Driver No 28 0.1302325581395348 43 5 0.0232558139534883 0
TOR1A-201 TOR1A O14656 Torsin-1A chr9 GO:0006979 Not Cancer Driver No 26 0.0783132530120482 0 0 0.0 3
TPO-201 TPO P07202 Thyroid peroxidase chr2 GO:0006979 Not Cancer Driver No 284 0.3043944265809217 163 61 0.0653804930332261 24
TRIM25-201 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 GO:0006979 Not Cancer Driver No 45 0.0714285714285714 226 11 0.0174603174603174 0
TXN2-201 TXN2 Q99757 Thioredoxin, mitochondrial chr22 GO:0006979 Not Cancer Driver No 15 0.0903614457831325 34 4 0.0240963855421686 0
UCN-201 UCN P55089 Urocortin chr2 GO:0006979 Not Cancer Driver No 7 0.0564516129032258 61 4 0.032258064516129 0
VNN1-201 VNN1 O95497 Pantetheinase chr6 GO:0006979 Not Cancer Driver No 67 0.1306042884990253 21 4 0.0077972709551656 0
WRN-201 WRN Q14191 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN chr8 GO:0006979 Census, Compendium Yes 133 0.092877094972067 374 29 0.0202513966480446 2