Total number of protein in "GO:0007059" GO term: 92
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABRAXAS2-201 | ABRAXAS2 | Q15018 | BRISC complex subunit Abraxas 2 | chr10 | GO:0007059 | Not Cancer Driver | No | 34 | 0.0819277108433735 | 207 | 20 | 0.0481927710843373 | 0 |
| ARL8A-201 | ARL8A | Q96BM9 | ADP-ribosylation factor-like protein 8A | chr1 | GO:0007059 | Not Cancer Driver | No | 22 | 0.1182795698924731 | 0 | 0 | 0.0 | 0 |
| ARL8B-201 | ARL8B | Q9NVJ2 | ADP-ribosylation factor-like protein 8B | chr3 | GO:0007059 | Not Cancer Driver | No | 19 | 0.1021505376344086 | 0 | 0 | 0.0 | 0 |
| BEX4-202 | BEX4 | Q9NWD9 | Protein BEX4 | chrX | GO:0007059 | Not Cancer Driver | No | 5 | 0.0416666666666666 | 121 | 5 | 0.0416666666666666 | 0 |
| BRCA1-203 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | GO:0007059 | Census, Compendium | Yes | 167 | 0.0896403650026838 | 1466 | 127 | 0.0681696188942565 | 34 |
| BUB1-201 | BUB1 | O43683 | Mitotic checkpoint serine/threonine-protein kinase BUB1 | chr2 | GO:0007059 | Not Cancer Driver | No | 101 | 0.0930875576036866 | 466 | 44 | 0.040552995391705 | 0 |
| C1orf112-202 | FIRRM | Q9NSG2 | FIGNL1-interacting regulator of recombination and mitosis | chr1 | GO:0007059 | Not Cancer Driver | No | 64 | 0.0750293083235638 | 26 | 1 | 0.0011723329425556 | 0 |
| C9orf78-201 | C9orf78 | Q9NZ63 | Splicing factor C9orf78 | chr9 | GO:0007059 | Not Cancer Driver | No | 20 | 0.0692041522491349 | 286 | 20 | 0.0692041522491349 | 0 |
| CDCA2-201 | CDCA2 | Q69YH5 | Cell division cycle-associated protein 2 | chr8 | GO:0007059 | Not Cancer Driver | No | 99 | 0.0967741935483871 | 834 | 84 | 0.0821114369501466 | 0 |
| CDK5RAP2-201 | CDK5RAP2 | Q96SN8 | CDK5 regulatory subunit-associated protein 2 | chr9 | GO:0007059 | Not Cancer Driver | No | 150 | 0.0792393026941362 | 1142 | 92 | 0.0486001056524035 | 0 |
| CENPC-201 | CENPC | Q03188 | Centromere protein C | chr4 | GO:0007059 | Not Cancer Driver | No | 55 | 0.0583244962884411 | 794 | 48 | 0.0509013785790031 | 0 |
| CENPE-201 | CENPE | Q02224 | Centromere-associated protein E | chr4 | GO:0007059 | Not Cancer Driver | No | 242 | 0.0895964457608293 | 1627 | 160 | 0.0592373195112921 | 2 |
| CENPF-201 | CENPF | P49454 | Centromere protein F | chr1 | GO:0007059 | Not Cancer Driver | No | 272 | 0.0873474630700064 | 2158 | 181 | 0.0581245985870263 | 0 |
| CENPH-201 | CENPH | Q9H3R5 | Centromere protein H | chr5 | GO:0007059 | Not Cancer Driver | No | 20 | 0.0809716599190283 | 85 | 6 | 0.0242914979757085 | 0 |
| CENPI-206 | CENPI | Q92674 | Centromere protein I | chrX | GO:0007059 | Not Cancer Driver | No | 67 | 0.0886243386243386 | 82 | 1 | 0.0013227513227513 | 0 |
| CENPK-202 | CENPK | Q9BS16 | Centromere protein K | chr5 | GO:0007059 | Not Cancer Driver | No | 20 | 0.0743494423791821 | 93 | 4 | 0.0148698884758364 | 0 |
| CENPL-210 | CENPL | Q8N0S6 | Centromere protein L | chr1 | GO:0007059 | Not Cancer Driver | No | 22 | 0.063953488372093 | 27 | 2 | 0.005813953488372 | 0 |
| CENPM-201 | CENPM | Q9NSP4 | Centromere protein M | chr22 | GO:0007059 | Not Cancer Driver | No | 7 | 0.0388888888888888 | 1 | 0 | 0.0 | 0 |
| CENPN-202 | CENPN | Q96H22 | Centromere protein N | chr16 | GO:0007059 | Not Cancer Driver | No | 26 | 0.0766961651917404 | 22 | 2 | 0.0058997050147492 | 0 |
| CENPO-202 | CENPO | Q9BU64 | Centromere protein O | chr2 | GO:0007059 | Not Cancer Driver | No | 12 | 0.04 | 54 | 2 | 0.0066666666666666 | 0 |
| CENPP-203 | CENPP | Q6IPU0 | Centromere protein P | chr9 | GO:0007059 | Not Cancer Driver | No | 20 | 0.0694444444444444 | 40 | 1 | 0.0034722222222222 | 0 |
| CENPQ-201 | CENPQ | Q7L2Z9 | Centromere protein Q | chr6 | GO:0007059 | Not Cancer Driver | No | 23 | 0.085820895522388 | 183 | 16 | 0.0597014925373134 | 0 |
| CENPS-201 | CENPS | Q8N2Z9 | Centromere protein S | chr1 | GO:0007059 | Not Cancer Driver | No | 6 | 0.0434782608695652 | 66 | 2 | 0.0144927536231884 | 0 |
| CENPS-CORT-205 | CENPS | Q8N2Z9 | Centromere protein S | chr1 | GO:0007059 | Not Cancer Driver | No | 6 | 0.0434782608695652 | 66 | 2 | 0.0144927536231884 | 0 |
| CENPT-208 | CENPT | Q96BT3 | Centromere protein T | chr16 | GO:0007059 | Not Cancer Driver | No | 49 | 0.0873440285204991 | 471 | 45 | 0.0802139037433155 | 0 |
| CENPU-201 | CENPU | Q71F23 | Centromere protein U | chr4 | GO:0007059 | Not Cancer Driver | No | 23 | 0.055023923444976 | 302 | 19 | 0.0454545454545454 | 0 |
| CENPW-203 | CENPW | Q5EE01 | Centromere protein W | chr6 | GO:0007059 | Not Cancer Driver | No | 7 | 0.0795454545454545 | 5 | 1 | 0.0113636363636363 | 0 |
| CENPX-202 | CENPX | A8MT69 | Centromere protein X | chr17 | GO:0007059 | Not Cancer Driver | No | 3 | 0.037037037037037 | 0 | 0 | 0.0 | 0 |
| CEP85-201 | CEP85 | Q6P2H3 | Centrosomal protein of 85 kDa | chr1 | GO:0007059 | Not Cancer Driver | No | 59 | 0.0774278215223097 | 611 | 47 | 0.0616797900262467 | 0 |
| CIAO1-203 | CIAO1 | O76071 | Probable cytosolic iron-sulfur protein assembly protein CIAO1 | chr2 | GO:0007059 | Not Cancer Driver | No | 25 | 0.0737463126843657 | 20 | 2 | 0.0058997050147492 | 0 |
| CIAO2A-201 | CIAO2A | Q9H5X1 | Cytosolic iron-sulfur assembly component 2A | chr15 | GO:0007059 | Not Cancer Driver | No | 20 | 0.125 | 28 | 3 | 0.01875 | 0 |
| CIAO2B-201 | CIAO2B | Q9Y3D0 | Cytosolic iron-sulfur assembly component 2B | chr16 | GO:0007059 | Not Cancer Driver | No | 7 | 0.0429447852760736 | 77 | 3 | 0.0184049079754601 | 0 |
| CTCF-201 | CTCF | P49711 | Transcriptional repressor CTCF | chr16 | GO:0007059 | Census, Compendium | Yes | 122 | 0.1678129298486932 | 482 | 62 | 0.0852819807427785 | 1 |
| DDX3X-244 | DDX3X | O00571 | ATP-dependent RNA helicase DDX3X | chrX | GO:0007059 | Census, Compendium | Yes | 91 | 0.1374622356495468 | 302 | 32 | 0.0483383685800604 | 18 |
| DIAPH3-205 | DIAPH3 | Q9NSV4 | Protein diaphanous homolog 3 | chr13 | GO:0007059 | Not Cancer Driver | No | 138 | 0.1156747694886839 | 493 | 62 | 0.0519698239731768 | 0 |
| DLGAP5-201 | DLGAP5 | Q15398 | Disks large-associated protein 5 | chr14 | GO:0007059 | Not Cancer Driver | No | 64 | 0.0756501182033096 | 683 | 55 | 0.0650118203309692 | 0 |
| ERCC2-204 | ERCC2 | P18074 | General transcription and DNA repair factor IIH helicase subunit XPD | chr19 | GO:0007059 | Census, Compendium | Yes | 103 | 0.1355263157894737 | 5 | 0 | 0.0 | 30 |
| ESCO2-201 | ESCO2 | Q56NI9 | N-acetyltransferase ESCO2 | chr8 | GO:0007059 | Not Cancer Driver | No | 42 | 0.0698835274542429 | 293 | 18 | 0.0299500831946755 | 1 |
| HJURP-202 | HJURP | Q8NCD3 | Holliday junction recognition protein | chr2 | GO:0007059 | Not Cancer Driver | No | 84 | 0.1122994652406417 | 580 | 65 | 0.0868983957219251 | 0 |
| INCENP-202 | INCENP | Q9NQS7 | Inner centromere protein | chr11 | GO:0007059 | Not Cancer Driver | No | 65 | 0.0708061002178649 | 863 | 63 | 0.0686274509803921 | 0 |
| ITGB3BP-201 | ITGB3BP | Q13352 | Centromere protein R | chr1 | GO:0007059 | Not Cancer Driver | No | 15 | 0.0847457627118644 | 123 | 12 | 0.0677966101694915 | 0 |
| KNSTRN-201 | KNSTRN | Q9Y448 | Small kinetochore-associated protein | chr15 | GO:0007059 | Census | Yes | 53 | 0.1677215189873417 | 248 | 47 | 0.1487341772151898 | 0 |
| MAP3K20-202 | MAP3K20 | Q9NYL2 | Mitogen-activated protein kinase kinase kinase 20 | chr2 | GO:0007059 | Not Cancer Driver | No | 71 | 0.08875 | 296 | 35 | 0.04375 | 2 |
| MAU2-201 | MAU2 | Q9Y6X3 | MAU2 chromatid cohesion factor homolog | chr19 | GO:0007059 | Not Cancer Driver | No | 54 | 0.0880913539967373 | 36 | 1 | 0.0016313213703099 | 0 |
| MIS12-206 | MIS12 | Q9H081 | Protein MIS12 homolog | chr17 | GO:0007059 | Not Cancer Driver | No | 7 | 0.0341463414634146 | 15 | 1 | 0.0048780487804878 | 0 |
| MIS18A-201 | MIS18A | Q9NYP9 | Protein Mis18-alpha | chr21 | GO:0007059 | Not Cancer Driver | No | 16 | 0.0686695278969957 | 15 | 1 | 0.0042918454935622 | 0 |
| MMS19-209 | MMS19 | Q96T76 | MMS19 nucleotide excision repair protein homolog | chr10 | GO:0007059 | Not Cancer Driver | No | 54 | 0.0524271844660194 | 11 | 0 | 0.0 | 0 |
| MTCL1-201 | MTCL1 | Q9Y4B5 | Microtubule cross-linking factor 1 | chr18 | GO:0007059 | Not Cancer Driver | No | 199 | 0.1044619422572178 | 1695 | 169 | 0.0887139107611548 | 0 |
| NAA60-202 | NAA60 | Q9H7X0 | N-alpha-acetyltransferase 60 | chr16 | GO:0007059 | Not Cancer Driver | No | 27 | 0.1115702479338843 | 0 | 0 | 0.0 | 0 |
| NDC80-201 | NDC80 | O14777 | Kinetochore protein NDC80 homolog | chr18 | GO:0007059 | Not Cancer Driver | No | 58 | 0.0903426791277258 | 313 | 34 | 0.0529595015576324 | 0 |
| NDE1-201 | NDE1 | Q9NXR1 | Nuclear distribution protein nudE homolog 1 | chr16 | GO:0007059 | Not Cancer Driver | No | 34 | 0.1014925373134328 | 316 | 33 | 0.0985074626865671 | 0 |
| NDEL1-201 | NDEL1 | Q9GZM8 | Nuclear distribution protein nudE-like 1 | chr17 | GO:0007059 | Not Cancer Driver | No | 23 | 0.0666666666666666 | 203 | 13 | 0.0376811594202898 | 0 |
| NEK2-202 | NEK2 | P51955 | Serine/threonine-protein kinase Nek2 | chr1 | GO:0007059 | Not Cancer Driver | No | 44 | 0.098876404494382 | 93 | 12 | 0.0269662921348314 | 0 |
| NEK6-201 | NEK6 | Q9HC98 | Serine/threonine-protein kinase Nek6 | chr9 | GO:0007059 | Not Cancer Driver | No | 25 | 0.0798722044728434 | 37 | 0 | 0.0 | 0 |
| NR3C1-203 | NR3C1 | P04150 | Glucocorticoid receptor | chr5 | GO:0007059 | Not Cancer Driver | No | 55 | 0.0707850707850707 | 364 | 20 | 0.0257400257400257 | 11 |
| NTMT1-203 | NTMT1 | Q9BV86 | N-terminal Xaa-Pro-Lys N-methyltransferase 1 | chr9 | GO:0007059 | Not Cancer Driver | No | 18 | 0.0807174887892376 | 1 | 0 | 0.0 | 0 |
| NUF2-201 | NUF2 | Q9BZD4 | Kinetochore protein Nuf2 | chr1 | GO:0007059 | Not Cancer Driver | No | 54 | 0.1163793103448275 | 75 | 10 | 0.021551724137931 | 0 |
| NUP37-209 | NUP37 | Q8NFH4 | Nucleoporin Nup37 | chr12 | GO:0007059 | Not Cancer Driver | No | 31 | 0.0950920245398773 | 0 | 0 | 0.0 | 0 |
| NUP43-201 | NUP43 | Q8NFH3 | Nucleoporin Nup43 | chr6 | GO:0007059 | Not Cancer Driver | No | 40 | 0.1052631578947368 | 104 | 7 | 0.0184210526315789 | 0 |
| OIP5-201 | OIP5 | O43482 | Protein Mis18-beta | chr15 | GO:0007059 | Not Cancer Driver | No | 26 | 0.1135371179039301 | 65 | 6 | 0.0262008733624454 | 0 |
| PHF13-201 | PHF13 | Q86YI8 | PHD finger protein 13 | chr1 | GO:0007059 | Not Cancer Driver | No | 36 | 0.12 | 158 | 18 | 0.06 | 0 |
| PMF1-202 | PMF1 | Q6P1K2 | Polyamine-modulated factor 1 | chr1 | GO:0007059 | Not Cancer Driver | No | 7 | 0.0341463414634146 | 76 | 1 | 0.0048780487804878 | 0 |
| PMF1-BGLAP-203 | PMF1 | Q6P1K2 | Polyamine-modulated factor 1 | chr1 | GO:0007059 | Not Cancer Driver | No | 7 | 0.0331753554502369 | 100 | 1 | 0.0047393364928909 | 0 |
| PPP2R1A-201 | PPP2R1A | P30153 | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform | chr19 | GO:0007059 | Census, Compendium | Yes | 169 | 0.2869269949066214 | 0 | 0 | 0.0 | 4 |
| RAD21-201 | RAD21 | O60216 | Double-strand-break repair protein rad21 homolog | chr8 | GO:0007059 | Census, Compendium | Yes | 84 | 0.1331220285261489 | 421 | 56 | 0.0887480190174326 | 3 |
| RAD21L1-203 | RAD21L1 | Q9H4I0 | Double-strand-break repair protein rad21-like protein 1 | chr20 | GO:0007059 | Not Cancer Driver | No | 9 | 0.0161870503597122 | 186 | 1 | 0.0017985611510791 | 0 |
| RCC1-214 | RCC1 | P18754 | Regulator of chromosome condensation | chr1 | GO:0007059 | Not Cancer Driver | No | 44 | 0.1045130641330166 | 146 | 16 | 0.0380047505938242 | 0 |
| RGS14-201 | RGS14 | O43566 | Regulator of G-protein signaling 14 | chr5 | GO:0007059 | Not Cancer Driver | No | 46 | 0.0812720848056537 | 309 | 27 | 0.0477031802120141 | 0 |
| RIOK3-201 | RIOK3 | O14730 | Serine/threonine-protein kinase RIO3 | chr18 | GO:0007059 | Not Cancer Driver | No | 39 | 0.0751445086705202 | 225 | 15 | 0.0289017341040462 | 0 |
| RPS3-217 | RPS3 | P23396 | Small ribosomal subunit protein uS3 | chr11 | GO:0007059 | Not Cancer Driver | No | 22 | 0.0905349794238683 | 48 | 4 | 0.0164609053497942 | 0 |
| SETDB2-202 | SETDB2 | Q96T68 | Histone-lysine N-methyltransferase SETDB2 | chr13 | GO:0007059 | Not Cancer Driver | No | 51 | 0.0709318497913769 | 255 | 20 | 0.0278164116828929 | 0 |
| SGO1-201 | SGO1 | Q5FBB7 | Shugoshin 1 | chr3 | GO:0007059 | Not Cancer Driver | No | 45 | 0.0802139037433155 | 361 | 29 | 0.0516934046345811 | 1 |
| SGO2-201 | SGO2 | Q562F6 | Shugoshin 2 | chr2 | GO:0007059 | Not Cancer Driver | No | 111 | 0.0877470355731225 | 1029 | 91 | 0.0719367588932806 | 0 |
| SKA1-201 | SKA1 | Q96BD8 | Spindle and kinetochore-associated protein 1 | chr18 | GO:0007059 | Not Cancer Driver | No | 15 | 0.0588235294117647 | 74 | 4 | 0.0156862745098039 | 0 |
| SKA2-201 | SKA2 | Q8WVK7 | Spindle and kinetochore-associated protein 2 | chr17 | GO:0007059 | Not Cancer Driver | No | 8 | 0.0661157024793388 | 44 | 3 | 0.024793388429752 | 0 |
| SKA3-202 | SKA3 | Q8IX90 | Spindle and kinetochore-associated protein 3 | chr13 | GO:0007059 | Not Cancer Driver | No | 35 | 0.0849514563106796 | 232 | 22 | 0.0533980582524271 | 0 |
| SLC25A5-201 | SLC25A5 | P05141 | ADP/ATP translocase 2 | chrX | GO:0007059 | Not Cancer Driver | No | 26 | 0.087248322147651 | 0 | 0 | 0.0 | 0 |
| SMC5-201 | SMC5 | Q8IY18 | Structural maintenance of chromosomes protein 5 | chr9 | GO:0007059 | Not Cancer Driver | No | 94 | 0.0853769300635785 | 381 | 35 | 0.0317892824704813 | 1 |
| SPAG5-201 | SPAG5 | Q96R06 | Sperm-associated antigen 5 | chr17 | GO:0007059 | Not Cancer Driver | No | 95 | 0.0796311818943839 | 636 | 59 | 0.0494551550712489 | 0 |
| SPC24-206 | SPC24 | Q8NBT2 | Kinetochore protein Spc24 | chr19 | GO:0007059 | Not Cancer Driver | No | 7 | 0.0355329949238578 | 88 | 3 | 0.015228426395939 | 0 |
| SPC25-201 | SPC25 | Q9HBM1 | Kinetochore protein Spc25 | chr2 | GO:0007059 | Not Cancer Driver | No | 10 | 0.0446428571428571 | 34 | 2 | 0.0089285714285714 | 0 |
| SRPK1-204 | SRPK1 | Q96SB4 | SRSF protein kinase 1 | chr6 | GO:0007059 | Not Cancer Driver | No | 52 | 0.0793893129770992 | 329 | 21 | 0.03206106870229 | 0 |
| TLK1-205 | TLK1 | Q9UKI8 | Serine/threonine-protein kinase tousled-like 1 | chr2 | GO:0007059 | Not Cancer Driver | No | 61 | 0.0796344647519582 | 389 | 32 | 0.04177545691906 | 0 |
| TLK2-201 | TLK2 | Q86UE8 | Serine/threonine-protein kinase tousled-like 2 | chr17 | GO:0007059 | Not Cancer Driver | No | 73 | 0.0945595854922279 | 436 | 31 | 0.0401554404145077 | 6 |
| TOP1-201 | TOP1 | P11387 | DNA topoisomerase 1 | chr20 | GO:0007059 | Census, Compendium | Yes | 50 | 0.065359477124183 | 391 | 19 | 0.0248366013071895 | 0 |
| TOP2A-201 | TOP2A | P11388 | DNA topoisomerase 2-alpha | chr17 | GO:0007059 | Compendium | Yes | 115 | 0.0751143043762246 | 509 | 46 | 0.0300457217504898 | 0 |
| TOP3B-201 | TOP3B | O95985 | DNA topoisomerase 3-beta-1 | chr22 | GO:0007059 | Not Cancer Driver | No | 76 | 0.0881670533642691 | 151 | 11 | 0.0127610208816705 | 0 |
| TTK-202 | TTK | P33981 | Dual specificity protein kinase TTK | chr6 | GO:0007059 | Not Cancer Driver | No | 106 | 0.1236872812135355 | 354 | 40 | 0.0466744457409568 | 0 |
| UBE2I-203 | UBE2I | P63279 | SUMO-conjugating enzyme UBC9 | chr16 | GO:0007059 | Not Cancer Driver | No | 16 | 0.1012658227848101 | 16 | 3 | 0.0189873417721519 | 0 |
| USP44-201 | USP44 | Q9H0E7 | Ubiquitin carboxyl-terminal hydrolase 44 | chr12 | GO:0007059 | Census, Compendium | Yes | 58 | 0.0814606741573033 | 115 | 5 | 0.0070224719101123 | 0 |
| USP9X-202 | USP9X | Q93008 | Probable ubiquitin carboxyl-terminal hydrolase FAF-X | chrX | GO:0007059 | Census, Compendium | Yes | 243 | 0.0951448707909162 | 405 | 33 | 0.0129209083790133 | 1 |
| UVRAG-201 | UVRAG | Q9P2Y5 | UV radiation resistance-associated gene protein | chr11 | GO:0007059 | Not Cancer Driver | No | 58 | 0.0829756795422031 | 243 | 21 | 0.0300429184549356 | 0 |