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Total number of protein in "GO:0007169" GO term:  103

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABI1-207 ABI1 Q8IZP0 Abl interactor 1 chr10 GO:0007169 Census, Compendium Yes 37 0.0728346456692913 360 28 0.0551181102362204 0
AHI1-201 AHI1 Q8N157 Jouberin chr6 GO:0007169 Not Cancer Driver No 74 0.0618729096989966 503 29 0.0242474916387959 6
ALK-201 ALK Q9UM73 ALK tyrosine kinase receptor chr2 GO:0007169 Census, Compendium Yes 233 0.1438271604938271 577 79 0.0487654320987654 12
ALKAL1-201 ALKAL1 Q6UXT8 ALK and LTK ligand 1 chr8 GO:0007169 Not Cancer Driver No 11 0.0852713178294573 49 1 0.0077519379844961 0
ALKAL2-204 ALKAL2 Q6UX46 ALK and LTK ligand 2 chr2 GO:0007169 Not Cancer Driver No 6 0.0394736842105263 31 0 0.0 0
ANGPTL1-201 ANGPTL1 O95841 Angiopoietin-related protein 1 chr1 GO:0007169 Not Cancer Driver No 47 0.0957230142566191 95 7 0.0142566191446028 0
AXL-201 AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0007169 Not Cancer Driver No 131 0.1465324384787472 342 51 0.0570469798657718 0
BCAR1-201 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 GO:0007169 Not Cancer Driver No 88 0.1011494252873563 681 64 0.0735632183908046 0
BDKRB2-203 BDKRB2 P30411 B2 bradykinin receptor chr14 GO:0007169 Not Cancer Driver No 60 0.1534526854219949 0 0 0.0 0
BDNF-202 BDNF P23560 Brain-derived neurotrophic factor chr11 GO:0007169 Not Cancer Driver No 33 0.1336032388663967 80 12 0.048582995951417 0
BLK-201 BLK P51451 Tyrosine-protein kinase Blk chr8 GO:0007169 Not Cancer Driver No 78 0.1544554455445544 75 17 0.0336633663366336 0
BLNK-201 BLNK Q8WV28 B-cell linker protein chr10 GO:0007169 Not Cancer Driver No 54 0.1184210526315789 380 48 0.1052631578947368 0
CASS4-205 CASS4 Q9NQ75 Cas scaffolding protein family member 4 chr20 GO:0007169 Not Cancer Driver No 160 0.2035623409669211 498 108 0.1374045801526717 0
CD3E-201 CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 GO:0007169 Not Cancer Driver No 16 0.0772946859903381 72 6 0.0289855072463768 0
CD4-201 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:0007169 Not Cancer Driver No 50 0.1091703056768559 56 7 0.0152838427947598 0
CD7-201 CD7 P09564 T-cell antigen CD7 chr17 GO:0007169 Not Cancer Driver No 21 0.0875 74 6 0.025 0
CD8A-201 CD8A P01732 T-cell surface glycoprotein CD8 alpha chain chr2 GO:0007169 Not Cancer Driver No 27 0.1148936170212766 28 2 0.0085106382978723 1
CD8B-203 CD8B P10966 T-cell surface glycoprotein CD8 beta chain chr2 GO:0007169 Not Cancer Driver No 33 0.1571428571428571 10 0 0.0 0
CLNK-201 CLNK Q7Z7G1 Cytokine-dependent hematopoietic cell linker chr4 GO:0007169 Not Cancer Driver No 53 0.1238317757009345 322 46 0.1074766355140186 0
CNKSR1-202 CNKSR1 Q969H4 Connector enhancer of kinase suppressor of ras 1 chr1 GO:0007169 Not Cancer Driver No 96 0.1333333333333333 408 54 0.075 0
CSF1-201 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0007169 Not Cancer Driver No 56 0.1010830324909747 342 38 0.0685920577617328 0
CSF1R-210 CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0007169 Census Yes 101 0.1039094650205761 124 12 0.0123456790123456 20
DDR1-225 DDR1 Q08345 Epithelial discoidin domain-containing receptor 1 chr6 GO:0007169 Not Cancer Driver No 98 0.1073384446878422 253 41 0.044906900328587 0
DDR2-201 DDR2 Q16832 Discoidin domain-containing receptor 2 chr1 GO:0007169 Census Yes 129 0.1508771929824561 120 25 0.0292397660818713 7
DOK1-201 DOK1 Q99704 Docking protein 1 chr2 GO:0007169 Not Cancer Driver No 47 0.0977130977130977 294 31 0.0644490644490644 0
DOK2-201 DOK2 O60496 Docking protein 2 chr8 GO:0007169 Not Cancer Driver No 40 0.0970873786407767 255 21 0.0509708737864077 0
DOK4-201 DOK4 Q8TEW6 Docking protein 4 chr16 GO:0007169 Not Cancer Driver No 31 0.0950920245398773 45 0 0.0 0
DOK5-201 DOK5 Q9P104 Docking protein 5 chr20 GO:0007169 Not Cancer Driver No 64 0.2091503267973856 15 4 0.0130718954248366 0
DOK6-201 DOK6 Q6PKX4 Docking protein 6 chr18 GO:0007169 Not Cancer Driver No 77 0.2326283987915408 48 8 0.0241691842900302 0
EFS-201 EFS O43281 Embryonal Fyn-associated substrate chr14 GO:0007169 Not Cancer Driver No 52 0.0926916221033868 416 36 0.0641711229946524 0
EGFR-201 EGFR P00533 Epidermal growth factor receptor chr7 GO:0007169 Census, Compendium Yes 346 0.2859504132231405 223 30 0.024793388429752 1
EPHA2-201 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0007169 Compendium Yes 147 0.1506147540983606 188 33 0.033811475409836 3
ERBB2-201 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0007169 Census, Compendium Yes 249 0.198406374501992 315 32 0.0254980079681274 1
ERBB3-201 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:0007169 Census, Compendium Yes 265 0.1974664679582712 398 59 0.0439642324888226 3
ERBB4-202 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 GO:0007169 Census, Compendium Yes 376 0.2874617737003058 324 95 0.0726299694189602 2
FGFR1-214 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 GO:0007169 Census, Compendium Yes 92 0.1119221411192214 231 26 0.0316301703163017 69
FGFR2-206 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0007169 Census, Compendium Yes 193 0.2350791717417783 229 34 0.0414129110840438 57
FGFR3-205 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 GO:0007169 Census, Compendium Yes 134 0.1662531017369727 241 18 0.0223325062034739 32
FGFR4-201 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 GO:0007169 Census, Compendium Yes 101 0.1259351620947631 163 27 0.0336658354114713 0
FGR-203 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:0007169 Not Cancer Driver No 67 0.1266540642722117 52 6 0.0113421550094517 0
FLT1-201 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:0007169 Not Cancer Driver No 212 0.1584454409566517 103 17 0.0127055306427503 0
FLT3-201 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0007169 Census, Compendium Yes 153 0.1540785498489426 64 19 0.0191339375629405 0
FLT4-201 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 GO:0007169 Census, Compendium Yes 203 0.1489361702127659 259 33 0.0242112986060161 14
FRK-201 FRK P42685 Tyrosine-protein kinase FRK chr6 GO:0007169 Not Cancer Driver No 59 0.1168316831683168 18 2 0.0039603960396039 0
FYN-202 FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0007169 Not Cancer Driver No 64 0.1191806331471136 71 11 0.0204841713221601 0
GAB2-202 GAB2 Q9UQC2 GRB2-associated-binding protein 2 chr11 GO:0007169 Not Cancer Driver No 63 0.0931952662721893 540 53 0.0784023668639053 0
GAB4-201 GAB4 Q2WGN9 GRB2-associated-binding protein 4 chr22 GO:0007169 Not Cancer Driver No 115 0.2003484320557491 431 78 0.1358885017421602 0
GFRA2-208 GFRA2 O00451 GDNF family receptor alpha-2 chr8 GO:0007169 Not Cancer Driver No 45 0.0969827586206896 71 20 0.043103448275862 0
HCK-202 HCK P08631 Tyrosine-protein kinase HCK chr20 GO:0007169 Not Cancer Driver No 89 0.1692015209125475 124 22 0.0418250950570342 0
IL31RA-212 IL31RA Q8NI17 Interleukin-31 receptor subunit alpha chr5 GO:0007169 Not Cancer Driver No 85 0.1112565445026178 162 26 0.0340314136125654 1
INSR-201 INSR P06213 Insulin receptor chr19 GO:0007169 Not Cancer Driver No 139 0.1005788712011577 282 37 0.0267727930535455 63
INSRR-201 INSRR P14616 Insulin receptor-related protein chr1 GO:0007169 Not Cancer Driver No 213 0.164225134926754 229 34 0.0262143407864302 0
KDR-201 KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0007169 Census, Compendium Yes 276 0.2035398230088495 276 40 0.0294985250737463 2
LCK-202 LCK P06239 Tyrosine-protein kinase Lck chr1 GO:0007169 Census Yes 76 0.1493123772102161 95 12 0.0235756385068762 1
LCP2-201 LCP2 Q13094 Lymphocyte cytosolic protein 2 chr5 GO:0007169 Not Cancer Driver No 75 0.1407129455909943 393 57 0.1069418386491557 0
LTK-201 LTK P29376 Leukocyte tyrosine kinase receptor chr15 GO:0007169 Not Cancer Driver No 63 0.0729166666666666 301 17 0.0196759259259259 0
LYN-202 LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0007169 Census Yes 78 0.15234375 85 10 0.01953125 0
MERTK-201 MERTK Q12866 Tyrosine-protein kinase Mer chr2 GO:0007169 Not Cancer Driver No 134 0.1341341341341341 161 25 0.025025025025025 3
MET-202 MET P08581 Hepatocyte growth factor receptor chr7 GO:0007169 Census, Compendium Yes 161 0.1158273381294964 62 10 0.0071942446043165 16
MPZL1-201 MPZL1 O95297 Myelin protein zero-like protein 1 chr1 GO:0007169 Not Cancer Driver No 33 0.1226765799256505 56 6 0.0223048327137546 0
MST1R-201 MST1R Q04912 Macrophage-stimulating protein receptor chr3 GO:0007169 Not Cancer Driver No 147 0.105 183 24 0.0171428571428571 1
MTSS1-205 MTSS1 O43312 Protein MTSS 1 chr8 GO:0007169 Not Cancer Driver No 82 0.1086092715231788 583 68 0.0900662251655629 0
MUSK-204 MUSK O15146 Muscle, skeletal receptor tyrosine-protein kinase chr9 GO:0007169 Not Cancer Driver No 145 0.1668584579976985 35 7 0.0080552359033371 7
NEDD9-202 NEDD9 Q14511 Enhancer of filamentation 1 chr6 GO:0007169 Not Cancer Driver No 80 0.0959232613908872 520 55 0.065947242206235 0
NGF-201 NGF P01138 Beta-nerve growth factor chr1 GO:0007169 Not Cancer Driver No 56 0.2323651452282157 94 21 0.0871369294605809 1
NRTN-201 NRTN Q99748 Neurturin chr19 GO:0007169 Not Cancer Driver No 6 0.0304568527918781 26 0 0.0 0
NTF3-201 NTF3 P20783 Neurotrophin-3 chr12 GO:0007169 Not Cancer Driver No 49 0.1906614785992217 102 23 0.0894941634241245 0
NTF4-201 NTF4 P34130 Neurotrophin-4 chr19 GO:0007169 Not Cancer Driver No 18 0.0857142857142857 56 3 0.0142857142857142 0
NTRK1-206 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0007169 Census, Compendium Yes 133 0.1670854271356784 57 8 0.0100502512562814 23
NTRK2-246 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0007169 Not Cancer Driver No 103 0.1253041362530413 117 14 0.0170316301703163 1
NTRK3-217 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0007169 Census, Compendium Yes 214 0.2550655542312277 56 15 0.0178784266984505 3
PDGFRA-201 PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0007169 Census, Compendium Yes 213 0.1955922865013774 173 36 0.0330578512396694 2
PDGFRB-201 PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0007169 Census, Compendium Yes 134 0.1211573236889692 233 40 0.0361663652802893 7
PIK3CB-214 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:0007169 Census, Compendium Yes 112 0.1046728971962616 42 3 0.002803738317757 0
PILRB-213 PILRB Q9UKJ0 Paired immunoglobulin-like type 2 receptor beta chr7 GO:0007169 Not Cancer Driver No 20 0.0881057268722467 26 1 0.0044052863436123 0
POLR1G-201 POLR1G O15446 DNA-directed RNA polymerase I subunit RPA34 chr19 GO:0007169 Not Cancer Driver No 37 0.0725490196078431 493 36 0.0705882352941176 0
PTK6-202 PTK6 Q13882 Protein-tyrosine kinase 6 chr20 GO:0007169 Census Yes 31 0.0687361419068736 12 0 0.0 0
PTPRG-203 PTPRG P23470 Receptor-type tyrosine-protein phosphatase gamma chr3 GO:0007169 Not Cancer Driver No 153 0.1058823529411764 466 44 0.0304498269896193 0
PTPRT-203 PTPRT O14522 Receptor-type tyrosine-protein phosphatase T chr20 GO:0007169 Census, Compendium Yes 460 0.3192227619708536 298 104 0.0721721027064538 0
RAPGEF1-201 RAPGEF1 Q13905 Rap guanine nucleotide exchange factor 1 chr9 GO:0007169 Not Cancer Driver No 119 0.1104921077065923 588 66 0.0612813370473537 0
RASGRP4-214 RASGRP4 Q8TDF6 RAS guanyl-releasing protein 4 chr19 GO:0007169 Not Cancer Driver No 70 0.1040118870728083 180 34 0.050520059435364 0
RET-202 RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0007169 Census, Compendium Yes 176 0.1579892280071813 108 11 0.0098743267504488 91
ROR1-201 ROR1 Q01973 Inactive tyrosine-protein kinase transmembrane receptor ROR1 chr1 GO:0007169 Not Cancer Driver No 113 0.1205976520811099 281 37 0.03948772678762 1
ROR2-201 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0007169 Not Cancer Driver No 164 0.1739130434782608 304 58 0.0615058324496288 5
ROS1-202 ROS1 P08922 Proto-oncogene tyrosine-protein kinase ROS chr6 GO:0007169 Census Yes 356 0.1516829995739241 197 45 0.0191734128674904 0
RYK-208 RYK P34925 Tyrosine-protein kinase RYK chr3 GO:0007169 Not Cancer Driver No 38 0.0626029654036243 85 3 0.0049423393739703 0
SAMD10-201 SAMD10 Q9BYL1 Sterile alpha motif domain-containing protein 10 chr20 GO:0007169 Not Cancer Driver No 16 0.0792079207920792 80 3 0.0148514851485148 0
SAMD12-201 SAMD12 Q8N8I0 Sterile alpha motif domain-containing protein 12 chr8 GO:0007169 Not Cancer Driver No 34 0.1691542288557214 60 7 0.0348258706467661 0
SH2B1-217 SH2B1 Q9NRF2 SH2B adapter protein 1 chr16 GO:0007169 Not Cancer Driver No 73 0.0965608465608465 615 58 0.0767195767195767 0
SH2B3-201 SH2B3 Q9UQQ2 SH2B adapter protein 3 chr12 GO:0007169 Census, Compendium Yes 39 0.0678260869565217 336 15 0.0260869565217391 0
SHC2-201 SHC2 P98077 SHC-transforming protein 2 chr19 GO:0007169 Not Cancer Driver No 50 0.0859106529209622 367 37 0.063573883161512 0
SHC3-202 SHC3 Q92529 SHC-transforming protein 3 chr9 GO:0007169 Not Cancer Driver No 68 0.1144781144781144 433 48 0.0808080808080808 0
SHC4-201 SHC4 Q6S5L8 SHC-transforming protein 4 chr15 GO:0007169 Not Cancer Driver No 59 0.0936507936507936 327 38 0.0603174603174603 0
SRMS-201 SRMS Q9H3Y6 Tyrosine-protein kinase Srms chr20 GO:0007169 Not Cancer Driver No 56 0.1147540983606557 48 7 0.0143442622950819 0
STAP1-201 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 GO:0007169 Not Cancer Driver No 46 0.1559322033898305 105 12 0.0406779661016949 0
SYK-204 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0007169 Census Yes 75 0.1181102362204724 131 20 0.0314960629921259 4
TEK-201 TEK Q02763 Angiopoietin-1 receptor chr9 GO:0007169 Not Cancer Driver No 145 0.1290035587188612 126 13 0.0115658362989323 9
TIE1-201 TIE1 P35590 Tyrosine-protein kinase receptor Tie-1 chr1 GO:0007169 Not Cancer Driver No 156 0.1370826010544815 223 36 0.031634446397188 0
TRADD-201 TRADD Q15628 Tumor necrosis factor receptor type 1-associated DEATH domain protein chr16 GO:0007169 Not Cancer Driver No 18 0.0576923076923076 74 4 0.0128205128205128 0
TRAT1-201 TRAT1 Q6PIZ9 T-cell receptor-associated transmembrane adapter 1 chr3 GO:0007169 Not Cancer Driver No 68 0.3655913978494624 131 56 0.3010752688172043 0
TYRO3-201 TYRO3 Q06418 Tyrosine-protein kinase receptor TYRO3 chr15 GO:0007169 Not Cancer Driver No 86 0.096629213483146 197 18 0.0202247191011235 0
YES1-201 YES1 P07947 Tyrosine-protein kinase Yes chr18 GO:0007169 Not Cancer Driver No 48 0.0883977900552486 63 9 0.0165745856353591 0
ZAP70-201 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 GO:0007169 Not Cancer Driver No 90 0.1453957996768982 119 13 0.0210016155088853 7