Total number of protein in "GO:0007173" GO term: 49
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1-201 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0007173 | Census, Compendium | Yes | 106 | 0.0938053097345132 | 609 | 53 | 0.0469026548672566 | 2 |
| ABL2-203 | ABL2 | P42684 | Tyrosine-protein kinase ABL2 | chr1 | GO:0007173 | Census, Compendium | Yes | 125 | 0.1057529610829103 | 644 | 53 | 0.0448392554991539 | 0 |
| AKT1-218 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0007173 | Census, Compendium | Yes | 99 | 0.20625 | 158 | 19 | 0.0395833333333333 | 4 |
| AREG-201 | AREG | P15514 | Amphiregulin | chr4 | GO:0007173 | Not Cancer Driver | No | 33 | 0.1309523809523809 | 152 | 26 | 0.1031746031746031 | 0 |
| BCAR1-201 | BCAR1 | P56945 | Breast cancer anti-estrogen resistance protein 1 | chr16 | GO:0007173 | Not Cancer Driver | No | 88 | 0.1011494252873563 | 681 | 64 | 0.0735632183908046 | 0 |
| BCAR3-201 | BCAR3 | O75815 | Breast cancer anti-estrogen resistance protein 3 | chr1 | GO:0007173 | Not Cancer Driver | No | 74 | 0.0896969696969696 | 397 | 34 | 0.0412121212121212 | 0 |
| BRAF-220 | BRAF | P15056 | Serine/threonine-protein kinase B-raf | chr7 | GO:0007173 | Census, Compendium | Yes | 755 | 0.9856396866840732 | 311 | 30 | 0.0391644908616188 | 35 |
| BTC-201 | BTC | P35070 | Probetacellulin | chr4 | GO:0007173 | Not Cancer Driver | No | 23 | 0.1292134831460674 | 12 | 5 | 0.0280898876404494 | 0 |
| CAMLG-201 | CAMLG | P49069 | Guided entry of tail-anchored proteins factor CAMLG | chr5 | GO:0007173 | Not Cancer Driver | No | 23 | 0.0777027027027027 | 158 | 13 | 0.0439189189189189 | 0 |
| EFEMP1-201 | EFEMP1 | Q12805 | EGF-containing fibulin-like extracellular matrix protein 1 | chr2 | GO:0007173 | Not Cancer Driver | No | 75 | 0.152129817444219 | 73 | 18 | 0.0365111561866125 | 1 |
| EGF-201 | EGF | P01133 | Pro-epidermal growth factor | chr4 | GO:0007173 | Not Cancer Driver | No | 149 | 0.1234465617232808 | 193 | 22 | 0.0182270091135045 | 1 |
| EGFR-201 | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:0007173 | Census, Compendium | Yes | 346 | 0.2859504132231405 | 223 | 30 | 0.024793388429752 | 1 |
| EPGN-202 | EPGN | Q6UW88 | Epigen | chr4 | GO:0007173 | Not Cancer Driver | No | 11 | 0.0714285714285714 | 0 | 0 | 0.0 | 0 |
| ERBB4-202 | ERBB4 | Q15303 | Receptor tyrosine-protein kinase erbB-4 | chr2 | GO:0007173 | Census, Compendium | Yes | 376 | 0.2874617737003058 | 324 | 95 | 0.0726299694189602 | 2 |
| ERBIN-201 | ERBIN | Q96RT1 | Erbin | chr5 | GO:0007173 | Not Cancer Driver | No | 113 | 0.080028328611898 | 971 | 78 | 0.0552407932011331 | 0 |
| EREG-201 | EREG | O14944 | Proepiregulin | chr4 | GO:0007173 | Not Cancer Driver | No | 19 | 0.1124260355029585 | 10 | 2 | 0.0118343195266272 | 0 |
| ERRFI1-201 | ERRFI1 | Q9UJM3 | ERBB receptor feedback inhibitor 1 | chr1 | GO:0007173 | Not Cancer Driver | No | 36 | 0.0779220779220779 | 299 | 23 | 0.0497835497835497 | 0 |
| FAM83A-209 | FAM83A | Q86UY5 | Protein FAM83A | chr8 | GO:0007173 | Not Cancer Driver | No | 52 | 0.1198156682027649 | 201 | 17 | 0.0391705069124423 | 0 |
| FAM83C-201 | FAM83C | Q9BQN1 | Protein FAM83C | chr20 | GO:0007173 | Not Cancer Driver | No | 111 | 0.1485943775100401 | 483 | 80 | 0.107095046854083 | 0 |
| GAB1-201 | GAB1 | Q13480 | GRB2-associated-binding protein 1 | chr4 | GO:0007173 | Not Cancer Driver | No | 54 | 0.0778097982708933 | 570 | 46 | 0.0662824207492795 | 1 |
| GAREM1-201 | GAREM1 | Q9H706 | GRB2-associated and regulator of MAPK protein 1 | chr18 | GO:0007173 | Not Cancer Driver | No | 95 | 0.1084474885844748 | 411 | 37 | 0.0422374429223744 | 0 |
| GRB2-202 | GRB2 | P62993 | Growth factor receptor-bound protein 2 | chr17 | GO:0007173 | Not Cancer Driver | No | 21 | 0.0967741935483871 | 10 | 0 | 0.0 | 0 |
| GRB7-201 | GRB7 | Q14451 | Growth factor receptor-bound protein 7 | chr17 | GO:0007173 | Not Cancer Driver | No | 61 | 0.1146616541353383 | 134 | 18 | 0.0338345864661654 | 0 |
| HBEGF-201 | HBEGF | Q99075 | Proheparin-binding EGF-like growth factor | chr5 | GO:0007173 | Not Cancer Driver | No | 11 | 0.0528846153846153 | 63 | 2 | 0.0096153846153846 | 0 |
| IQGAP1-201 | IQGAP1 | P46940 | Ras GTPase-activating-like protein IQGAP1 | chr15 | GO:0007173 | Not Cancer Driver | No | 137 | 0.0826795413397706 | 351 | 25 | 0.0150875075437537 | 0 |
| KIF16B-201 | KIF16B | Q96L93 | Kinesin-like protein KIF16B | chr20 | GO:0007173 | Not Cancer Driver | No | 158 | 0.119969627942293 | 437 | 42 | 0.0318906605922551 | 0 |
| NCK2-201 | NCK2 | O43639 | Cytoplasmic protein NCK2 | chr2 | GO:0007173 | Not Cancer Driver | No | 66 | 0.1736842105263158 | 88 | 15 | 0.0394736842105263 | 0 |
| NPR2-201 | NPR2 | P20594 | Atrial natriuretic peptide receptor 2 | chr9 | GO:0007173 | Not Cancer Driver | No | 106 | 0.1012416427889207 | 91 | 9 | 0.0085959885386819 | 20 |
| PDPK1-202 | PDPK1 | O15530 | 3-phosphoinositide-dependent protein kinase 1 | chr16 | GO:0007173 | Not Cancer Driver | No | 23 | 0.0413669064748201 | 121 | 9 | 0.0161870503597122 | 0 |
| PIGR-201 | PIGR | P01833 | Polymeric immunoglobulin receptor | chr1 | GO:0007173 | Not Cancer Driver | No | 97 | 0.1269633507853403 | 178 | 27 | 0.0353403141361256 | 0 |
| PIK3C2A-206 | PIK3C2A | O00443 | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | chr11 | GO:0007173 | Not Cancer Driver | No | 119 | 0.0705812574139976 | 351 | 24 | 0.0142348754448398 | 0 |
| PIK3CA-201 | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0007173 | Census, Compendium | Yes | 1425 | 1.3342696629213484 | 38 | 9 | 0.0084269662921348 | 44 |
| PLCE1-202 | PLCE1 | Q9P212 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 | chr10 | GO:0007173 | Not Cancer Driver | No | 267 | 0.1159860990443093 | 785 | 79 | 0.0343179843614248 | 1 |
| PLCG1-202 | PLCG1 | P19174 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | chr20 | GO:0007173 | Census, Compendium | Yes | 129 | 0.1 | 187 | 15 | 0.0116279069767441 | 0 |
| PRICKLE1-201 | PRICKLE1 | Q96MT3 | Prickle-like protein 1 | chr12 | GO:0007173 | Not Cancer Driver | No | 118 | 0.1419975932611311 | 485 | 71 | 0.0854392298435619 | 3 |
| PTK2-228 | PTK2 | Q05397 | Focal adhesion kinase 1 | chr8 | GO:0007173 | Not Cancer Driver | No | 102 | 0.0969581749049429 | 426 | 45 | 0.0427756653992395 | 0 |
| PTK2B-201 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0007173 | Not Cancer Driver | No | 117 | 0.1159563924677899 | 263 | 23 | 0.0227948463825569 | 0 |
| PTPN11-201 | PTPN11 | Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | chr12 | GO:0007173 | Census, Compendium | Yes | 92 | 0.1551433389544688 | 260 | 27 | 0.0455311973018549 | 44 |
| REPS2-202 | REPS2 | Q8NFH8 | RalBP1-associated Eps domain-containing protein 2 | chrX | GO:0007173 | Not Cancer Driver | No | 60 | 0.0909090909090909 | 464 | 47 | 0.0712121212121212 | 0 |
| SHC1-202 | SHC1 | P29353 | SHC-transforming protein 1 | chr1 | GO:0007173 | Not Cancer Driver | No | 58 | 0.0994854202401372 | 400 | 41 | 0.0703259005145797 | 0 |
| SHC3-202 | SHC3 | Q92529 | SHC-transforming protein 3 | chr9 | GO:0007173 | Not Cancer Driver | No | 68 | 0.1144781144781144 | 433 | 48 | 0.0808080808080808 | 0 |
| SLC30A10-202 | SLC30A10 | Q6XR72 | Calcium/manganese antiporter SLC30A10 | chr1 | GO:0007173 | Not Cancer Driver | No | 57 | 0.1175257731958762 | 61 | 4 | 0.0082474226804123 | 2 |
| SOCS5-202 | SOCS5 | O75159 | Suppressor of cytokine signaling 5 | chr2 | GO:0007173 | Not Cancer Driver | No | 63 | 0.1175373134328358 | 298 | 30 | 0.0559701492537313 | 0 |
| SOS1-202 | SOS1 | Q07889 | Son of sevenless homolog 1 | chr2 | GO:0007173 | Compendium | Yes | 155 | 0.1162790697674418 | 459 | 47 | 0.0352588147036759 | 32 |
| SOX9-201 | SOX9 | P48436 | Transcription factor SOX-9 | chr17 | GO:0007173 | Compendium | Yes | 69 | 0.1355599214145383 | 497 | 66 | 0.1296660117878192 | 13 |
| SRC-204 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0007173 | Census | Yes | 40 | 0.0746268656716417 | 130 | 10 | 0.0186567164179104 | 1 |
| TDGF1-201 | TDGF1 | P13385 | Teratocarcinoma-derived growth factor 1 | chr3 | GO:0007173 | Not Cancer Driver | No | 34 | 0.1808510638297872 | 25 | 2 | 0.0106382978723404 | 0 |
| TGFA-201 | TGFA | P01135 | Protransforming growth factor alpha | chr2 | GO:0007173 | Not Cancer Driver | No | 17 | 0.10625 | 0 | 0 | 0.0 | 0 |
| VIL1-201 | VIL1 | P09327 | Villin-1 | chr2 | GO:0007173 | Not Cancer Driver | No | 90 | 0.1088270858524788 | 222 | 26 | 0.0314389359129383 | 0 |