Total number of protein in "GO:0007179" GO term: 96
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACVR1-207 | ACVR1 | Q04771 | Activin receptor type-1 | chr2 | GO:0007179 | Census, Compendium | Yes | 71 | 0.1394891944990176 | 21 | 8 | 0.0157170923379174 | 6 |
| ACVRL1-201 | ACVRL1 | P37023 | Serine/threonine-protein kinase receptor R3 | chr12 | GO:0007179 | Not Cancer Driver | No | 80 | 0.1590457256461232 | 60 | 10 | 0.0198807157057654 | 64 |
| ADAM9-209 | ADAM9 | Q13443 | Disintegrin and metalloproteinase domain-containing protein 9 | chr8 | GO:0007179 | Not Cancer Driver | No | 59 | 0.072039072039072 | 130 | 7 | 0.0085470085470085 | 0 |
| AMHR2-201 | AMHR2 | Q16671 | Anti-Muellerian hormone type-2 receptor | chr12 | GO:0007179 | Not Cancer Driver | No | 67 | 0.1169284467713787 | 118 | 9 | 0.0157068062827225 | 8 |
| APOA1-201 | APOA1 | P02647 | Apolipoprotein A-I | chr11 | GO:0007179 | Not Cancer Driver | No | 25 | 0.0936329588014981 | 131 | 9 | 0.0337078651685393 | 3 |
| APPL1-201 | APPL1 | Q9UKG1 | DCC-interacting protein 13-alpha | chr3 | GO:0007179 | Not Cancer Driver | No | 35 | 0.0493653032440056 | 293 | 18 | 0.0253878702397743 | 1 |
| APPL2-201 | APPL2 | Q8NEU8 | DCC-interacting protein 13-beta | chr12 | GO:0007179 | Not Cancer Driver | No | 49 | 0.0737951807228915 | 149 | 8 | 0.0120481927710843 | 0 |
| ARRB2-201 | ARRB2 | P32121 | Beta-arrestin-2 | chr17 | GO:0007179 | Not Cancer Driver | No | 39 | 0.0953545232273838 | 122 | 19 | 0.0464547677261613 | 0 |
| BAMBI-201 | BAMBI | Q13145 | BMP and activin membrane-bound inhibitor homolog | chr10 | GO:0007179 | Not Cancer Driver | No | 24 | 0.0923076923076923 | 31 | 5 | 0.0192307692307692 | 0 |
| BMPR1A-201 | BMPR1A | P36894 | Bone morphogenetic protein receptor type-1A | chr10 | GO:0007179 | Census, Compendium | Yes | 37 | 0.0695488721804511 | 21 | 0 | 0.0 | 8 |
| CAV2-201 | CAV2 | P51636 | Caveolin-2 | chr7 | GO:0007179 | Not Cancer Driver | No | 13 | 0.0802469135802469 | 5 | 2 | 0.0123456790123456 | 0 |
| CDH5-201 | CDH5 | P33151 | Cadherin-5 | chr16 | GO:0007179 | Not Cancer Driver | No | 121 | 0.1543367346938775 | 305 | 44 | 0.0561224489795918 | 0 |
| CHST11-201 | CHST11 | Q9NPF2 | Carbohydrate sulfotransferase 11 | chr12 | GO:0007179 | Census | Yes | 47 | 0.1335227272727272 | 46 | 10 | 0.0284090909090909 | 0 |
| CITED1-211 | CITED1 | Q99966 | Cbp/p300-interacting transactivator 1 | chrX | GO:0007179 | Not Cancer Driver | No | 16 | 0.082901554404145 | 167 | 15 | 0.077720207253886 | 0 |
| CITED2-201 | CITED2 | Q99967 | Cbp/p300-interacting transactivator 2 | chr6 | GO:0007179 | Not Cancer Driver | No | 22 | 0.0814814814814814 | 232 | 19 | 0.0703703703703703 | 0 |
| CLDN5-204 | CLDN5 | O00501 | Claudin-5 | chr22 | GO:0007179 | Not Cancer Driver | No | 17 | 0.0779816513761468 | 0 | 0 | 0.0 | 0 |
| COL1A2-201 | COL1A2 | P08123 | Collagen alpha-2(I) chain | chr7 | GO:0007179 | Not Cancer Driver | No | 84 | 0.0614934114202049 | 1160 | 50 | 0.0366032210834553 | 81 |
| COL3A1-201 | COL3A1 | P02461 | Collagen alpha-1(III) chain | chr2 | GO:0007179 | Census | Yes | 49 | 0.0334242837653478 | 1183 | 6 | 0.0040927694406548 | 86 |
| DAB2-201 | DAB2 | P98082 | Disabled homolog 2 | chr5 | GO:0007179 | Not Cancer Driver | No | 108 | 0.1402597402597402 | 684 | 94 | 0.122077922077922 | 0 |
| DUSP22-201 | DUSP22 | Q9NRW4 | Dual specificity protein phosphatase 22 | chr6 | GO:0007179 | Not Cancer Driver | No | 76 | 0.4130434782608695 | 0 | 0 | 0.0 | 0 |
| ENG-202 | ENG | P17813 | Endoglin | chr9 | GO:0007179 | Not Cancer Driver | No | 47 | 0.0714285714285714 | 114 | 11 | 0.0167173252279635 | 29 |
| FERMT2-201 | FERMT2 | Q96AC1 | Fermitin family homolog 2 | chr14 | GO:0007179 | Not Cancer Driver | No | 44 | 0.0647058823529411 | 102 | 8 | 0.0117647058823529 | 0 |
| FLCN-201 | FLCN | Q8NFG4 | Folliculin | chr17 | GO:0007179 | Census, Compendium | Yes | 49 | 0.0846286701208981 | 159 | 20 | 0.0345423143350604 | 6 |
| FNTA-201 | FNTA | P49354 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | chr8 | GO:0007179 | Not Cancer Driver | No | 29 | 0.0765171503957783 | 92 | 9 | 0.0237467018469656 | 0 |
| FOS-201 | FOS | P01100 | Protein c-Fos | chr14 | GO:0007179 | Not Cancer Driver | No | 37 | 0.0973684210526315 | 247 | 28 | 0.0736842105263157 | 0 |
| FOXH1-201 | FOXH1 | O75593 | Forkhead box protein H1 | chr8 | GO:0007179 | Not Cancer Driver | No | 38 | 0.1041095890410958 | 217 | 19 | 0.0520547945205479 | 0 |
| FSHB-203 | FSHB | P01225 | Follitropin subunit beta | chr11 | GO:0007179 | Not Cancer Driver | No | 31 | 0.2403100775193798 | 0 | 0 | 0.0 | 1 |
| FURIN-201 | FURIN | P09958 | Furin | chr15 | GO:0007179 | Not Cancer Driver | No | 72 | 0.0906801007556675 | 283 | 30 | 0.0377833753148614 | 0 |
| FUT8-216 | FUT8 | Q9BYC5 | Alpha-(1,6)-fucosyltransferase | chr14 | GO:0007179 | Not Cancer Driver | No | 55 | 0.0956521739130434 | 81 | 17 | 0.0295652173913043 | 1 |
| GCNT2-216 | GCNT2 | Q8N0V5 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase | chr6 | GO:0007179 | Not Cancer Driver | No | 27 | 0.0671641791044776 | 3 | 0 | 0.0 | 0 |
| GDF10-201 | GDF10 | P55107 | Growth/differentiation factor 10 | chr10 | GO:0007179 | Not Cancer Driver | No | 81 | 0.1694560669456067 | 254 | 54 | 0.1129707112970711 | 0 |
| GDF15-201 | GDF15 | Q99988 | Growth/differentiation factor 15 | chr19 | GO:0007179 | Not Cancer Driver | No | 28 | 0.0909090909090909 | 145 | 15 | 0.0487012987012987 | 0 |
| GDF5-201 | GDF5 | P43026 | Growth/differentiation factor 5 | chr20 | GO:0007179 | Not Cancer Driver | No | 89 | 0.1776447105788423 | 257 | 48 | 0.0958083832335329 | 23 |
| GDF9-207 | GDF9 | O60383 | Growth/differentiation factor 9 | chr5 | GO:0007179 | Not Cancer Driver | No | 50 | 0.1101321585903083 | 54 | 13 | 0.0286343612334801 | 0 |
| GLG1-202 | GLG1 | Q92896 | Golgi apparatus protein 1 | chr16 | GO:0007179 | Not Cancer Driver | No | 97 | 0.0822731128074639 | 103 | 4 | 0.003392705682782 | 0 |
| HIPK2-202 | HIPK2 | Q9H2X6 | Homeodomain-interacting protein kinase 2 | chr7 | GO:0007179 | Not Cancer Driver | No | 124 | 0.1035058430717863 | 686 | 76 | 0.0634390651085141 | 0 |
| HPGD-202 | HPGD | P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | chr4 | GO:0007179 | Not Cancer Driver | No | 19 | 0.0714285714285714 | 4 | 1 | 0.0037593984962406 | 2 |
| ID1-202 | ID1 | P41134 | DNA-binding protein inhibitor ID-1 | chr20 | GO:0007179 | Not Cancer Driver | No | 18 | 0.1161290322580645 | 17 | 6 | 0.0387096774193548 | 0 |
| ITGA8-201 | ITGA8 | P53708 | Integrin alpha-8 | chr10 | GO:0007179 | Not Cancer Driver | No | 224 | 0.2107243650047036 | 114 | 25 | 0.0235183443085606 | 1 |
| ITGB1-201 | ITGB1 | P05556 | Integrin beta-1 | chr10 | GO:0007179 | Not Cancer Driver | No | 73 | 0.0914786967418546 | 84 | 8 | 0.0100250626566416 | 0 |
| ITGB5-201 | ITGB5 | P18084 | Integrin beta-5 | chr3 | GO:0007179 | Not Cancer Driver | No | 62 | 0.0775969962453066 | 27 | 3 | 0.0037546933667083 | 0 |
| ITGB6-201 | ITGB6 | P18564 | Integrin beta-6 | chr2 | GO:0007179 | Not Cancer Driver | No | 89 | 0.1129441624365482 | 27 | 3 | 0.0038071065989847 | 3 |
| ITGB8-201 | ITGB8 | P26012 | Integrin beta-8 | chr7 | GO:0007179 | Not Cancer Driver | No | 89 | 0.1157347204161248 | 26 | 2 | 0.0026007802340702 | 0 |
| JUN-201 | JUN | P05412 | Transcription factor Jun | chr1 | GO:0007179 | Census | Yes | 26 | 0.0785498489425981 | 283 | 17 | 0.0513595166163142 | 0 |
| LEFTY1-201 | LEFTY1 | O75610 | Left-right determination factor 1 | chr1 | GO:0007179 | Not Cancer Driver | No | 38 | 0.1038251366120218 | 65 | 6 | 0.0163934426229508 | 0 |
| LPXN-201 | LPXN | O60711 | Leupaxin | chr11 | GO:0007179 | Not Cancer Driver | No | 30 | 0.077720207253886 | 135 | 10 | 0.0259067357512953 | 0 |
| LRRC32-201 | LRRC32 | Q14392 | Transforming growth factor beta activator LRRC32 | chr11 | GO:0007179 | Not Cancer Driver | No | 107 | 0.161631419939577 | 28 | 3 | 0.0045317220543806 | 0 |
| LTBP2-201 | LTBP2 | Q14767 | Latent-transforming growth factor beta-binding protein 2 | chr14 | GO:0007179 | Not Cancer Driver | No | 239 | 0.1312465678198792 | 634 | 84 | 0.0461285008237232 | 1 |
| LTBP3-201 | LTBP3 | Q9NS15 | Latent-transforming growth factor beta-binding protein 3 | chr11 | GO:0007179 | Not Cancer Driver | No | 87 | 0.066768994627782 | 356 | 20 | 0.0153491941673062 | 0 |
| LTBP4-203 | LTBP4 | Q8N2S1 | Latent-transforming growth factor beta-binding protein 4 | chr19 | GO:0007179 | Not Cancer Driver | No | 149 | 0.0917487684729064 | 435 | 32 | 0.0197044334975369 | 1 |
| MAP3K7-204 | MAP3K7 | O43318 | Mitogen-activated protein kinase kinase kinase 7 | chr6 | GO:0007179 | Not Cancer Driver | No | 74 | 0.1221122112211221 | 333 | 42 | 0.0693069306930693 | 6 |
| MSTN-201 | MSTN | O14793 | Growth/differentiation factor 8 | chr2 | GO:0007179 | Not Cancer Driver | No | 54 | 0.144 | 65 | 11 | 0.0293333333333333 | 0 |
| NDP-202 | NDP | Q00604 | Norrin | chrX | GO:0007179 | Not Cancer Driver | No | 11 | 0.0827067669172932 | 0 | 0 | 0.0 | 45 |
| NLK-201 | NLK | Q9UBE8 | Serine/threonine-protein kinase NLK | chr17 | GO:0007179 | Not Cancer Driver | No | 42 | 0.079696394686907 | 152 | 15 | 0.0284629981024667 | 0 |
| NODAL-201 | NODAL | Q96S42 | Nodal homolog | chr10 | GO:0007179 | Not Cancer Driver | No | 34 | 0.0979827089337175 | 34 | 9 | 0.0259365994236311 | 4 |
| NPNT-202 | NPNT | Q6UXI9 | Nephronectin | chr4 | GO:0007179 | Not Cancer Driver | No | 71 | 0.1256637168141593 | 218 | 26 | 0.0460176991150442 | 0 |
| NRROS-201 | NRROS | Q86YC3 | Transforming growth factor beta activator LRRC33 | chr3 | GO:0007179 | Not Cancer Driver | No | 86 | 0.1242774566473988 | 8 | 1 | 0.0014450867052023 | 0 |
| ONECUT1-201 | ONECUT1 | Q9UBC0 | Hepatocyte nuclear factor 6 | chr15 | GO:0007179 | Not Cancer Driver | No | 57 | 0.1225806451612903 | 409 | 47 | 0.1010752688172043 | 0 |
| ONECUT2-202 | ONECUT2 | O95948 | One cut domain family member 2 | chr18 | GO:0007179 | Not Cancer Driver | No | 58 | 0.115079365079365 | 409 | 39 | 0.0773809523809523 | 0 |
| PARP1-203 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | GO:0007179 | Not Cancer Driver | No | 88 | 0.0867850098619329 | 322 | 28 | 0.0276134122287968 | 0 |
| PML-201 | PML | P29590 | Protein PML | chr15 | GO:0007179 | Census, Compendium | Yes | 87 | 0.0986394557823129 | 312 | 28 | 0.0317460317460317 | 0 |
| PSG9-202 | PSG9 | Q00887 | Pregnancy-specific beta-1-glycoprotein 9 | chr19 | GO:0007179 | Not Cancer Driver | No | 96 | 0.2253521126760563 | 41 | 7 | 0.0164319248826291 | 0 |
| PTK2-228 | PTK2 | Q05397 | Focal adhesion kinase 1 | chr8 | GO:0007179 | Not Cancer Driver | No | 102 | 0.0969581749049429 | 426 | 45 | 0.0427756653992395 | 0 |
| PTPRK-206 | PTPRK | Q15262 | Receptor-type tyrosine-protein phosphatase kappa | chr6 | GO:0007179 | Census, Compendium | Yes | 233 | 0.1619179986101459 | 302 | 44 | 0.0305767894371091 | 0 |
| PXN-201 | PXN | P49023 | Paxillin | chr12 | GO:0007179 | Not Cancer Driver | No | 41 | 0.0693739424703891 | 342 | 14 | 0.0236886632825719 | 0 |
| SIRT1-201 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0007179 | Not Cancer Driver | No | 43 | 0.0575635876840696 | 435 | 19 | 0.0254350736278447 | 0 |
| SKI-201 | SKI | P12755 | Ski oncogene | chr1 | GO:0007179 | Census | Yes | 41 | 0.0563186813186813 | 434 | 27 | 0.037087912087912 | 8 |
| SKIL-201 | SKIL | P12757 | Ski-like protein | chr3 | GO:0007179 | Not Cancer Driver | No | 55 | 0.0804093567251462 | 359 | 24 | 0.0350877192982456 | 0 |
| SMAD1-201 | SMAD1 | Q15797 | Mothers against decapentaplegic homolog 1 | chr4 | GO:0007179 | Not Cancer Driver | No | 39 | 0.0838709677419354 | 162 | 19 | 0.0408602150537634 | 0 |
| SMAD2-201 | SMAD2 | Q15796 | Mothers against decapentaplegic homolog 2 | chr18 | GO:0007179 | Census, Compendium | Yes | 58 | 0.1241970021413276 | 137 | 11 | 0.0235546038543897 | 3 |
| SMAD3-201 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0007179 | Census, Compendium | Yes | 80 | 0.188235294117647 | 113 | 15 | 0.0352941176470588 | 5 |
| SMAD4-201 | SMAD4 | Q13485 | Mothers against decapentaplegic homolog 4 | chr18 | GO:0007179 | Census, Compendium | Yes | 172 | 0.3115942028985507 | 195 | 16 | 0.0289855072463768 | 6 |
| SMAD5-211 | SMAD5 | Q99717 | Mothers against decapentaplegic homolog 5 | chr5 | GO:0007179 | Not Cancer Driver | No | 25 | 0.053763440860215 | 172 | 6 | 0.0129032258064516 | 0 |
| SMAD6-201 | SMAD6 | O43541 | Mothers against decapentaplegic homolog 6 | chr15 | GO:0007179 | Not Cancer Driver | No | 29 | 0.0584677419354838 | 249 | 4 | 0.0080645161290322 | 7 |
| SMAD7-201 | SMAD7 | O15105 | Mothers against decapentaplegic homolog 7 | chr18 | GO:0007179 | Not Cancer Driver | No | 38 | 0.0892018779342723 | 140 | 0 | 0.0 | 0 |
| SMAD9-202 | SMAD9 | O15198 | Mothers against decapentaplegic homolog 9 | chr13 | GO:0007179 | Not Cancer Driver | No | 64 | 0.1370449678800856 | 132 | 14 | 0.0299785867237687 | 1 |
| SRC-204 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0007179 | Census | Yes | 40 | 0.0746268656716417 | 130 | 10 | 0.0186567164179104 | 1 |
| STAT3-201 | STAT3 | P40763 | Signal transducer and activator of transcription 3 | chr17 | GO:0007179 | Census, Compendium | Yes | 93 | 0.1207792207792207 | 152 | 16 | 0.0207792207792207 | 15 |
| TAB1-201 | TAB1 | Q15750 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 | chr22 | GO:0007179 | Not Cancer Driver | No | 62 | 0.123015873015873 | 233 | 23 | 0.0456349206349206 | 0 |
| TGFB1-201 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | GO:0007179 | Not Cancer Driver | No | 30 | 0.0769230769230769 | 44 | 3 | 0.0076923076923076 | 8 |
| TGFB2-202 | TGFB2 | P61812 | Transforming growth factor beta-2 proprotein | chr1 | GO:0007179 | Not Cancer Driver | No | 44 | 0.1062801932367149 | 47 | 5 | 0.0120772946859903 | 4 |
| TGFB3-201 | TGFB3 | P10600 | Transforming growth factor beta-3 proprotein | chr14 | GO:0007179 | Not Cancer Driver | No | 27 | 0.0655339805825242 | 97 | 6 | 0.0145631067961165 | 1 |
| TGFBR1-202 | TGFBR1 | P36897 | TGF-beta receptor type-1 | chr9 | GO:0007179 | Not Cancer Driver | No | 57 | 0.1133200795228628 | 23 | 3 | 0.0059642147117296 | 13 |
| TGFBR2-201 | TGFBR2 | P37173 | TGF-beta receptor type-2 | chr3 | GO:0007179 | Census, Compendium | Yes | 93 | 0.164021164021164 | 61 | 15 | 0.0264550264550264 | 21 |
| TGFBR3-201 | TGFBR3 | Q03167 | Transforming growth factor beta receptor type 3 | chr1 | GO:0007179 | Not Cancer Driver | No | 104 | 0.1222091656874265 | 268 | 36 | 0.0423031727379553 | 0 |
| TGFBRAP1-201 | TGFBRAP1 | Q8WUH2 | Transforming growth factor-beta receptor-associated protein 1 | chr2 | GO:0007179 | Not Cancer Driver | No | 108 | 0.1255813953488372 | 37 | 8 | 0.0093023255813953 | 0 |
| TP53-201 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0007179 | Census, Compendium | Yes | 2742 | 6.977099236641221 | 282 | 1364 | 3.470737913486005 | 60 |
| USP15-201 | USP15 | Q9Y4E8 | Ubiquitin carboxyl-terminal hydrolase 15 | chr12 | GO:0007179 | Not Cancer Driver | No | 103 | 0.1049949031600407 | 260 | 31 | 0.0316004077471967 | 0 |
| USP9X-202 | USP9X | Q93008 | Probable ubiquitin carboxyl-terminal hydrolase FAF-X | chrX | GO:0007179 | Census, Compendium | Yes | 243 | 0.0951448707909162 | 405 | 33 | 0.0129209083790133 | 1 |
| USP9Y-201 | USP9Y | O00507 | Probable ubiquitin carboxyl-terminal hydrolase FAF-Y | chrY | GO:0007179 | Not Cancer Driver | No | 60 | 0.0234833659491193 | 349 | 6 | 0.0023483365949119 | 0 |
| WFIKKN1-201 | WFIKKN1 | Q96NZ8 | WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 | chr16 | GO:0007179 | Not Cancer Driver | No | 28 | 0.0510948905109489 | 90 | 6 | 0.010948905109489 | 0 |
| WFIKKN2-201 | WFIKKN2 | Q8TEU8 | WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 | chr17 | GO:0007179 | Not Cancer Driver | No | 99 | 0.171875 | 95 | 28 | 0.0486111111111111 | 0 |
| ZFYVE9-201 | ZFYVE9 | O95405 | Zinc finger FYVE domain-containing protein 9 | chr1 | GO:0007179 | Not Cancer Driver | No | 123 | 0.0863157894736842 | 670 | 68 | 0.047719298245614 | 0 |
| ZMIZ1-201 | ZMIZ1 | Q9ULJ6 | Zinc finger MIZ domain-containing protein 1 | chr10 | GO:0007179 | Not Cancer Driver | No | 115 | 0.1077788191190253 | 764 | 83 | 0.077788191190253 | 4 |
| ZMIZ2-202 | ZMIZ2 | Q8NF64 | Zinc finger MIZ domain-containing protein 2 | chr7 | GO:0007179 | Not Cancer Driver | No | 86 | 0.0934782608695652 | 673 | 61 | 0.0663043478260869 | 0 |
| ZYX-201 | ZYX | Q15942 | Zyxin | chr7 | GO:0007179 | Not Cancer Driver | No | 49 | 0.0856643356643356 | 385 | 29 | 0.0506993006993006 | 0 |