Filter in search result
Please select a valid state.

Total number of protein in "GO:0007219" GO term:  113

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADAM10-201 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 GO:0007219 Not Cancer Driver No 73 0.0975935828877005 156 18 0.0240641711229946 4
ADAM17-201 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0007219 Not Cancer Driver No 63 0.0764563106796116 182 17 0.020631067961165 0
AGXT-201 AGXT P21549 Alanine--glyoxylate aminotransferase chr2 GO:0007219 Not Cancer Driver No 47 0.1198979591836734 20 0 0.0 33
ANGPT4-201 ANGPT4 Q9Y264 Angiopoietin-4 chr20 GO:0007219 Not Cancer Driver No 87 0.172962226640159 152 31 0.0616302186878727 0
ANXA4-201 ANXA4 P09525 Annexin A4 chr2 GO:0007219 Not Cancer Driver No 35 0.1090342679127725 36 3 0.0093457943925233 0
APH1A-203 APH1A Q96BI3 Gamma-secretase subunit APH-1A chr1 GO:0007219 Not Cancer Driver No 29 0.1094339622641509 0 0 0.0 0
APH1B-201 APH1B Q8WW43 Gamma-secretase subunit APH-1B chr15 GO:0007219 Not Cancer Driver No 15 0.0583657587548638 0 0 0.0 0
APP-201 APP P05067 Amyloid-beta precursor protein chr21 GO:0007219 Not Cancer Driver No 94 0.122077922077922 419 52 0.0675324675324675 12
ASCL1-201 ASCL1 P50553 Achaete-scute homolog 1 chr12 GO:0007219 Not Cancer Driver No 26 0.1101694915254237 183 18 0.0762711864406779 0
ATOH1-201 ATOH1 Q92858 Transcription factor ATOH1 chr4 GO:0007219 Not Cancer Driver No 54 0.1525423728813559 329 46 0.1299435028248587 0
BMP2-201 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0007219 Not Cancer Driver No 54 0.1363636363636363 140 22 0.0555555555555555 0
CDH6-201 CDH6 P55285 Cadherin-6 chr5 GO:0007219 Not Cancer Driver No 216 0.2734177215189873 339 94 0.1189873417721519 0
CDK6-202 CDK6 Q00534 Cyclin-dependent kinase 6 chr7 GO:0007219 Census Yes 25 0.0766871165644171 24 3 0.00920245398773 1
CDKN1B-201 CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0007219 Census, Compendium Yes 14 0.0707070707070707 199 14 0.0707070707070707 0
CEBPA-201 CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 GO:0007219 Census, Compendium Yes 10 0.0279329608938547 343 10 0.0279329608938547 1
CFAP58-202 CFAP58 Q5T655 Cilia- and flagella-associated protein 58 chr10 GO:0007219 Not Cancer Driver No 149 0.1708715596330275 393 58 0.0665137614678899 0
CHAC1-203 CHAC1 Q9BUX1 Glutathione-specific gamma-glutamylcyclotransferase 1 chr15 GO:0007219 Not Cancer Driver No 20 0.09009009009009 49 4 0.018018018018018 0
CNTN1-208 CNTN1 Q12860 Contactin-1 chr12 GO:0007219 Not Cancer Driver No 210 0.206286836935167 221 39 0.0383104125736738 0
CNTN6-205 CNTN6 Q9UQ52 Contactin-6 chr3 GO:0007219 Not Cancer Driver No 239 0.2324902723735408 175 45 0.0437743190661478 0
DLL1-201 DLL1 O00548 Delta-like protein 1 chr6 GO:0007219 Not Cancer Driver No 81 0.1120331950207468 145 15 0.0207468879668049 1
DLL3-201 DLL3 Q9NYJ7 Delta-like protein 3 chr19 GO:0007219 Not Cancer Driver No 49 0.0792880258899676 119 4 0.0064724919093851 1
DLL4-201 DLL4 Q9NR61 Delta-like protein 4 chr15 GO:0007219 Not Cancer Driver No 64 0.0934306569343065 73 11 0.0160583941605839 6
DLX1-203 DLX1 P56177 Homeobox protein DLX-1 chr2 GO:0007219 Not Cancer Driver No 21 0.0823529411764705 183 17 0.0666666666666666 0
DLX2-201 DLX2 Q07687 Homeobox protein DLX-2 chr2 GO:0007219 Not Cancer Driver No 33 0.1006097560975609 264 24 0.073170731707317 0
DNER-201 DNER Q8NFT8 Delta and Notch-like epidermal growth factor-related receptor chr2 GO:0007219 Not Cancer Driver No 131 0.1777476255088195 106 17 0.0230664857530529 0
DTX1-204 DTX1 Q86Y01 E3 ubiquitin-protein ligase DTX1 chr12 GO:0007219 Compendium Yes 78 0.1258064516129032 304 34 0.0548387096774193 0
DTX2-206 DTX2 Q86UW9 Probable E3 ubiquitin-protein ligase DTX2 chr7 GO:0007219 Not Cancer Driver No 59 0.0948553054662379 295 26 0.0418006430868167 0
DTX3-201 DTX3 Q8N9I9 Probable E3 ubiquitin-protein ligase DTX3 chr12 GO:0007219 Not Cancer Driver No 47 0.1354466858789625 182 25 0.0720461095100864 0
DTX3L-201 DTX3L Q8TDB6 E3 ubiquitin-protein ligase DTX3L chr3 GO:0007219 Not Cancer Driver No 60 0.081081081081081 260 19 0.0256756756756756 0
DTX4-201 DTX4 Q9Y2E6 E3 ubiquitin-protein ligase DTX4 chr11 GO:0007219 Not Cancer Driver No 59 0.0953150242326332 326 39 0.0630048465266559 0
ENST00000676884 PSEN2 P49810 Presenilin-2 chr1 GO:0007219 Not Cancer Driver No 0 0.0 0 0 0.0 0
EPN1-202 EPN1 Q9Y6I3 Epsin-1 chr19 GO:0007219 Not Cancer Driver No 62 0.1076388888888889 494 52 0.0902777777777777 0
ETV2-203 ETV2 O00321 ETS translocation variant 2 chr19 GO:0007219 Not Cancer Driver No 21 0.0614035087719298 228 14 0.0409356725146198 0
FBXW7-201 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:0007219 Census, Compendium Yes 289 0.4087694483734088 232 15 0.0212164073550212 17
FOXA1-201 FOXA1 P55317 Hepatocyte nuclear factor 3-alpha chr14 GO:0007219 Census, Compendium Yes 85 0.1800847457627118 295 44 0.0932203389830508 0
FOXC1-201 FOXC1 Q12948 Forkhead box protein C1 chr6 GO:0007219 Not Cancer Driver No 23 0.0415913200723327 409 14 0.0253164556962025 25
FOXC2-201 FOXC2 Q99958 Forkhead box protein C2 chr16 GO:0007219 Not Cancer Driver No 52 0.1037924151696606 370 31 0.06187624750499 1
GMDS-202 GMDS O60547 GDP-mannose 4,6 dehydratase chr6 GO:0007219 Not Cancer Driver No 42 0.1129032258064516 53 6 0.0161290322580645 0
GOT1-201 GOT1 P17174 Aspartate aminotransferase, cytoplasmic chr10 GO:0007219 Not Cancer Driver No 36 0.0871670702179176 35 5 0.0121065375302663 0
GRIP2-205 GRIP2 Q9C0E4 Glutamate receptor-interacting protein 2 chr3 GO:0007219 Not Cancer Driver No 0 0.0 590 0 0.0 0
GSX2-201 GSX2 Q9BZM3 GS homeobox 2 chr4 GO:0007219 Not Cancer Driver No 34 0.1118421052631579 211 21 0.069078947368421 1
HES1-201 HES1 Q14469 Transcription factor HES-1 chr3 GO:0007219 Not Cancer Driver No 35 0.125 227 30 0.1071428571428571 0
HES5-201 HES5 Q5TA89 Transcription factor HES-5 chr1 GO:0007219 Not Cancer Driver No 1 0.0060240963855421 73 0 0.0 0
HES7-201 HES7 Q9BYE0 Transcription factor HES-7 chr17 GO:0007219 Not Cancer Driver No 4 0.0177777777777777 167 4 0.0177777777777777 3
HEY1-202 HEY1 Q9Y5J3 Hairy/enhancer-of-split related with YRPW motif protein 1 chr8 GO:0007219 Census Yes 26 0.0855263157894736 172 12 0.0394736842105263 0
HEY2-201 HEY2 Q9UBP5 Hairy/enhancer-of-split related with YRPW motif protein 2 chr6 GO:0007219 Not Cancer Driver No 50 0.1483679525222551 181 21 0.0623145400593471 0
HEYL-201 HEYL Q9NQ87 Hairy/enhancer-of-split related with YRPW motif-like protein chr1 GO:0007219 Not Cancer Driver No 29 0.0884146341463414 199 13 0.0396341463414634 0
HNF1B-203 HNF1B P35680 Hepatocyte nuclear factor 1-beta chr17 GO:0007219 Not Cancer Driver No 68 0.1220825852782764 476 57 0.1023339317773788 19
HOXD3-205 HOXD3 P31249 Homeobox protein Hox-D3 chr2 GO:0007219 Not Cancer Driver No 54 0.125 358 52 0.1203703703703703 0
IFT172-201 IFT172 Q9UG01 Intraflagellar transport protein 172 homolog chr2 GO:0007219 Not Cancer Driver No 154 0.0880503144654088 96 4 0.0022870211549456 8
IFT74-201 IFT74 Q96LB3 Intraflagellar transport protein 74 homolog chr9 GO:0007219 Not Cancer Driver No 32 0.0533333333333333 492 26 0.0433333333333333 2
IL17A-201 IL17A Q16552 Interleukin-17A chr6 GO:0007219 Not Cancer Driver No 45 0.2903225806451613 56 16 0.1032258064516129 0
IL2RA-203 IL2RA P01589 Interleukin-2 receptor subunit alpha chr10 GO:0007219 Not Cancer Driver No 37 0.1360294117647058 132 19 0.0698529411764705 2
ITGB1BP1-202 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0007219 Not Cancer Driver No 13 0.065 58 1 0.005 0
JAG1-201 JAG1 P78504 Protein jagged-1 chr20 GO:0007219 Not Cancer Driver No 133 0.1091954022988505 172 14 0.0114942528735632 45
JAG2-201 JAG2 Q9Y219 Protein jagged-2 chr14 GO:0007219 Not Cancer Driver No 109 0.0880452342487883 159 22 0.0177705977382875 1
KCNA5-201 KCNA5 P22460 Potassium voltage-gated channel subfamily A member 5 chr12 GO:0007219 Not Cancer Driver No 185 0.3017944535073409 221 51 0.0831973898858075 0
KRT19-201 KRT19 P08727 Keratin, type I cytoskeletal 19 chr17 GO:0007219 Not Cancer Driver No 42 0.105 165 18 0.045 0
MAML1-201 MAML1 Q92585 Mastermind-like protein 1 chr5 GO:0007219 Not Cancer Driver No 77 0.0757874015748031 1010 77 0.0757874015748031 0
MAML2-201 MAML2 Q8IZL2 Mastermind-like protein 2 chr11 GO:0007219 Census, Compendium Yes 52 0.0449826989619377 1159 54 0.046712802768166 0
MAML3-202 MAML3 Q96JK9 Mastermind-like protein 3 chr4 GO:0007219 Not Cancer Driver No 85 0.0746924428822495 1128 85 0.0746924428822495 0
MECP2-201 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0007219 Not Cancer Driver No 44 0.0905349794238683 482 43 0.088477366255144 32
MESP1-201 MESP1 Q9BRJ9 Mesoderm posterior protein 1 chr15 GO:0007219 Not Cancer Driver No 8 0.0298507462686567 250 7 0.0261194029850746 0
MESP2-201 MESP2 Q0VG99 Mesoderm posterior protein 2 chr15 GO:0007219 Not Cancer Driver No 30 0.0755667506297229 345 23 0.0579345088161209 0
MIB1-201 MIB1 Q86YT6 E3 ubiquitin-protein ligase MIB1 chr18 GO:0007219 Not Cancer Driver No 96 0.0954274353876739 284 26 0.025844930417495 1
MIB2-201 MIB2 Q96AX9 E3 ubiquitin-protein ligase MIB2 chr1 GO:0007219 Not Cancer Driver No 64 0.0670157068062827 309 14 0.0146596858638743 0
NCSTN-201 NCSTN Q92542 Nicastrin chr1 GO:0007219 Not Cancer Driver No 69 0.0973201692524682 72 10 0.0141043723554301 1
NEURL1-201 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0007219 Not Cancer Driver No 50 0.0871080139372822 153 10 0.0174216027874564 0
NEURL1B-201 NEURL1B A8MQ27 E3 ubiquitin-protein ligase NEURL1B chr5 GO:0007219 Not Cancer Driver No 7 0.0126126126126126 250 3 0.0054054054054054 0
NEUROD4-201 NEUROD4 Q9HD90 Neurogenic differentiation factor 4 chr12 GO:0007219 Not Cancer Driver No 89 0.2688821752265861 237 62 0.1873111782477341 0
NFKBIA-201 NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 GO:0007219 Compendium Yes 34 0.1072555205047318 102 10 0.0315457413249211 1
NKAP-201 NKAP Q8N5F7 NF-kappa-B-activating protein chrX GO:0007219 Not Cancer Driver No 58 0.1397590361445783 409 57 0.1373493975903614 2
NLE1-202 NLE1 Q9NVX2 Notchless protein homolog 1 chr17 GO:0007219 Not Cancer Driver No 43 0.088659793814433 21 2 0.0041237113402061 0
NOTCH1-204 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0007219 Census, Compendium Yes 312 0.1221135029354207 690 71 0.0277886497064579 3
NOTCH2-201 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0007219 Census, Compendium Yes 191 0.0772966410360178 631 61 0.0246863617968433 1
NOTCH2NLA-201 NOTCH2NLA Q7Z3S9 Notch homolog 2 N-terminal-like protein A chr1 GO:0007219 Not Cancer Driver No 49 0.2076271186440678 17 1 0.0042372881355932 0
NOTCH2NLB-201 NOTCH2NLA Q7Z3S9 Notch homolog 2 N-terminal-like protein A chr1 GO:0007219 Not Cancer Driver No 0 0.0 16 0 0.0 0
NOTCH2NLC-202 NOTCH2NLC P0DPK4 Notch homolog 2 N-terminal-like protein C chr1 GO:0007219 Not Cancer Driver No 0 0.0 24 0 0.0 0
NOTCH3-201 NOTCH3 Q9UM47 Neurogenic locus notch homolog protein 3 chr19 GO:0007219 Not Cancer Driver No 241 0.1038345540715209 560 61 0.0262817750969409 89
NR0B2-201 NR0B2 Q15466 Nuclear receptor subfamily 0 group B member 2 chr1 GO:0007219 Not Cancer Driver No 30 0.1167315175097276 10 2 0.0077821011673151 0
NR1H4-209 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0007219 Not Cancer Driver No 82 0.1687242798353909 78 13 0.0267489711934156 0
NRARP-201 NRARP Q7Z6K4 Notch-regulated ankyrin repeat-containing protein chr9 GO:0007219 Not Cancer Driver No 10 0.087719298245614 11 1 0.0087719298245614 0
NRIP2-201 NRIP2 Q9BQI9 Nuclear receptor-interacting protein 2 chr12 GO:0007219 Not Cancer Driver No 26 0.092526690391459 160 13 0.0462633451957295 0
ONECUT1-201 ONECUT1 Q9UBC0 Hepatocyte nuclear factor 6 chr15 GO:0007219 Not Cancer Driver No 57 0.1225806451612903 409 47 0.1010752688172043 0
PERP-201 PERP Q96FX8 p53 apoptosis effector related to PMP-22 chr6 GO:0007219 Not Cancer Driver No 25 0.1295336787564766 0 0 0.0 1
PGAM2-201 PGAM2 P15259 Phosphoglycerate mutase 2 chr7 GO:0007219 Not Cancer Driver No 38 0.150197628458498 83 12 0.0474308300395256 4
PLN-201 PLN P26678 Cardiac phospholamban chr6 GO:0007219 Not Cancer Driver No 5 0.0961538461538461 0 0 0.0 1
POFUT1-202 POFUT1 Q9H488 GDP-fucose protein O-fucosyltransferase 1 chr20 GO:0007219 Not Cancer Driver No 37 0.095360824742268 17 0 0.0 0
PSEN1-201 PSEN1 P49768 Presenilin-1 chr14 GO:0007219 Not Cancer Driver No 43 0.0920770877944325 134 18 0.038543897216274 69
PSEN2-202 PSEN2 P49810 Presenilin-2 chr1 GO:0007219 Not Cancer Driver No 58 0.1294642857142857 91 13 0.0290178571428571 4
PSENEN-202 PSENEN Q9NZ42 Gamma-secretase subunit PEN-2 chr19 GO:0007219 Not Cancer Driver No 14 0.1386138613861386 0 0 0.0 0
PTP4A3-204 PTP4A3 O75365 Protein tyrosine phosphatase type IVA 3 chr8 GO:0007219 Not Cancer Driver No 27 0.1560693641618497 3 0 0.0 0
RBPJ-206 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0007219 Not Cancer Driver No 32 0.064 151 10 0.02 2
RIPPLY2-202 RIPPLY2 Q5TAB7 Protein ripply2 chr6 GO:0007219 Not Cancer Driver No 20 0.15625 83 12 0.09375 0
RITA1-201 RITA1 Q96K30 RBPJ-interacting and tubulin-associated protein 1 chr12 GO:0007219 Not Cancer Driver No 22 0.0817843866171003 270 22 0.0817843866171003 0
S1PR3-202 S1PR3 Q99500 Sphingosine 1-phosphate receptor 3 chr9 GO:0007219 Not Cancer Driver No 53 0.1402116402116402 29 4 0.0105820105820105 0
SEL1L-201 SEL1L Q9UBV2 Protein sel-1 homolog 1 chr14 GO:0007219 Not Cancer Driver No 64 0.0806045340050377 188 10 0.0125944584382871 0
SIX1-205 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0007219 Census, Compendium Yes 27 0.0950704225352112 144 16 0.056338028169014 7
SNAI1-201 SNAI1 O95863 Zinc finger protein SNAI1 chr20 GO:0007219 Not Cancer Driver No 41 0.1553030303030303 98 8 0.0303030303030303 0
SNAI2-201 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0007219 Not Cancer Driver No 43 0.1604477611940298 52 8 0.0298507462686567 0
SORBS2-201 SORBS2 O94875 Sorbin and SH3 domain-containing protein 2 chr4 GO:0007219 Not Cancer Driver No 122 0.1109090909090909 857 98 0.0890909090909091 0
SOX9-201 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0007219 Compendium Yes 69 0.1355599214145383 497 66 0.1296660117878192 13
SPEN-201 SPEN Q96T58 Msx2-interacting protein chr1 GO:0007219 Census, Compendium Yes 341 0.0930676855895196 3072 297 0.0810589519650655 0
SUSD5-201 SUSD5 O60279 Sushi domain-containing protein 5 chr3 GO:0007219 Not Cancer Driver No 60 0.095389507154213 360 48 0.0763116057233704 0
TBX2-201 TBX2 Q13207 T-box transcription factor TBX2 chr17 GO:0007219 Not Cancer Driver No 64 0.0898876404494382 401 30 0.0421348314606741 1
TGFBR2-201 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0007219 Census, Compendium Yes 93 0.164021164021164 61 15 0.0264550264550264 21
TIMP4-201 TIMP4 Q99727 Metalloproteinase inhibitor 4 chr3 GO:0007219 Not Cancer Driver No 23 0.1026785714285714 8 0 0.0 0
TMEM100-201 TMEM100 Q9NV29 Transmembrane protein 100 chr17 GO:0007219 Not Cancer Driver No 22 0.1641791044776119 0 0 0.0 0
TP63-201 TP63 Q9H3D4 Tumor protein 63 chr3 GO:0007219 Census, Compendium Yes 198 0.2911764705882353 398 120 0.1764705882352941 21
TRAF7-201 TRAF7 Q6Q0C0 E3 ubiquitin-protein ligase TRAF7 chr16 GO:0007219 Census Yes 65 0.0970149253731343 121 13 0.0194029850746268 4
TSPEAR-201 TSPEAR Q8WU66 Thrombospondin-type laminin G domain and EAR repeat-containing protein chr21 GO:0007219 Not Cancer Driver No 113 0.1689088191330343 7 1 0.0014947683109118 0
WDR12-201 WDR12 Q9GZL7 Ribosome biogenesis protein WDR12 chr2 GO:0007219 Not Cancer Driver No 29 0.0685579196217494 36 0 0.0 0
ZNF423-202 ZNF423 Q2M1K9 Zinc finger protein 423 chr16 GO:0007219 Not Cancer Driver No 282 0.219626168224299 418 86 0.0669781931464174 2