Total number of protein in "GO:0007265" GO term: 82
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADRA2A-201 | ADRA2A | P08913 | Alpha-2A adrenergic receptor | chr10 | GO:0007265 | Not Cancer Driver | No | 46 | 0.0989247311827957 | 162 | 9 | 0.0193548387096774 | 0 |
| BRAP-202 | BRAP | Q7Z569 | BRCA1-associated protein | chr12 | GO:0007265 | Not Cancer Driver | No | 54 | 0.0912162162162162 | 193 | 16 | 0.027027027027027 | 0 |
| CCNA2-201 | CCNA2 | P20248 | Cyclin-A2 | chr4 | GO:0007265 | Not Cancer Driver | No | 34 | 0.0787037037037037 | 187 | 14 | 0.0324074074074074 | 0 |
| CDK2-201 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | GO:0007265 | Not Cancer Driver | No | 17 | 0.0570469798657718 | 0 | 0 | 0.0 | 0 |
| CDKN1A-201 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | GO:0007265 | Census, Compendium | Yes | 38 | 0.2317073170731707 | 121 | 25 | 0.1524390243902439 | 0 |
| CDKN2A-201 | CDKN2A | P42771 | Cyclin-dependent kinase inhibitor 2A | chr9 | GO:0007265 | Census, Compendium | Yes | 151 | 0.967948717948718 | 83 | 81 | 0.5192307692307693 | 30 |
| CRKL-201 | CRKL | P46109 | Crk-like protein | chr22 | GO:0007265 | Not Cancer Driver | No | 24 | 0.0792079207920792 | 160 | 17 | 0.0561056105610561 | 0 |
| CSF1-201 | CSF1 | P09603 | Macrophage colony-stimulating factor 1 | chr1 | GO:0007265 | Not Cancer Driver | No | 56 | 0.1010830324909747 | 342 | 38 | 0.0685920577617328 | 0 |
| DHCR24-201 | DHCR24 | Q15392 | Delta(24)-sterol reductase | chr1 | GO:0007265 | Not Cancer Driver | No | 36 | 0.0697674418604651 | 0 | 0 | 0.0 | 6 |
| DOK1-201 | DOK1 | Q99704 | Docking protein 1 | chr2 | GO:0007265 | Not Cancer Driver | No | 47 | 0.0977130977130977 | 294 | 31 | 0.0644490644490644 | 0 |
| DOK2-201 | DOK2 | O60496 | Docking protein 2 | chr8 | GO:0007265 | Not Cancer Driver | No | 40 | 0.0970873786407767 | 255 | 21 | 0.0509708737864077 | 0 |
| DOK4-201 | DOK4 | Q8TEW6 | Docking protein 4 | chr16 | GO:0007265 | Not Cancer Driver | No | 31 | 0.0950920245398773 | 45 | 0 | 0.0 | 0 |
| DOK5-201 | DOK5 | Q9P104 | Docking protein 5 | chr20 | GO:0007265 | Not Cancer Driver | No | 64 | 0.2091503267973856 | 15 | 4 | 0.0130718954248366 | 0 |
| DOK6-201 | DOK6 | Q6PKX4 | Docking protein 6 | chr18 | GO:0007265 | Not Cancer Driver | No | 77 | 0.2326283987915408 | 48 | 8 | 0.0241691842900302 | 0 |
| ENST00000514667 | RAPGEF6 | Q8TEU7 | Rap guanine nucleotide exchange factor 6 | chr5 | GO:0007265 | Not Cancer Driver | No | 148 | 0.0896426408237431 | 769 | 68 | 0.0411871592973955 | 0 |
| ERAS-202 | ERAS | Q7Z444 | GTPase ERas | chrX | GO:0007265 | Not Cancer Driver | No | 33 | 0.1416309012875536 | 29 | 2 | 0.0085836909871244 | 0 |
| FGF2-201 | FGF2 | P09038 | Fibroblast growth factor 2 | chr4 | GO:0007265 | Not Cancer Driver | No | 17 | 0.0590277777777777 | 183 | 5 | 0.0173611111111111 | 0 |
| G3BP1-201 | G3BP1 | Q13283 | Ras GTPase-activating protein-binding protein 1 | chr5 | GO:0007265 | Not Cancer Driver | No | 55 | 0.1180257510729613 | 352 | 38 | 0.0815450643776824 | 0 |
| G3BP2-202 | G3BP2 | Q9UN86 | Ras GTPase-activating protein-binding protein 2 | chr4 | GO:0007265 | Not Cancer Driver | No | 41 | 0.0850622406639004 | 384 | 34 | 0.0705394190871369 | 0 |
| GNB1-201 | GNB1 | P62873 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | chr1 | GO:0007265 | Not Cancer Driver | No | 42 | 0.1235294117647058 | 24 | 2 | 0.0058823529411764 | 14 |
| GRAP-201 | GRAP | Q13588 | GRB2-related adapter protein | chr17 | GO:0007265 | Not Cancer Driver | No | 9 | 0.0414746543778801 | 0 | 0 | 0.0 | 1 |
| GRAP2-201 | GRAP2 | O75791 | GRB2-related adapter protein 2 | chr22 | GO:0007265 | Not Cancer Driver | No | 49 | 0.1484848484848485 | 151 | 16 | 0.0484848484848484 | 0 |
| GRB2-202 | GRB2 | P62993 | Growth factor receptor-bound protein 2 | chr17 | GO:0007265 | Not Cancer Driver | No | 21 | 0.0967741935483871 | 10 | 0 | 0.0 | 0 |
| HRAS-201 | HRAS | P01112 | GTPase HRas | chr11 | GO:0007265 | Census, Compendium | Yes | 129 | 0.6825396825396826 | 16 | 2 | 0.0105820105820105 | 10 |
| IGF1-201 | IGF1 | P05019 | Insulin-like growth factor I | chr12 | GO:0007265 | Not Cancer Driver | No | 30 | 0.1538461538461538 | 87 | 18 | 0.0923076923076923 | 0 |
| IQGAP3-201 | IQGAP3 | Q86VI3 | Ras GTPase-activating-like protein IQGAP3 | chr1 | GO:0007265 | Not Cancer Driver | No | 169 | 0.1036174126302881 | 259 | 26 | 0.0159411404046597 | 0 |
| KITLG-205 | KITLG | P21583 | Kit ligand | chr12 | GO:0007265 | Not Cancer Driver | No | 38 | 0.1391941391941392 | 61 | 6 | 0.0219780219780219 | 1 |
| KRAS-201 | KRAS | P01116 | GTPase KRas | chr12 | GO:0007265 | Census, Compendium | Yes | 771 | 4.079365079365079 | 7 | 2 | 0.0105820105820105 | 22 |
| KSR1-219 | KSR1 | Q8IVT5 | Kinase suppressor of Ras 1 | chr17 | GO:0007265 | Not Cancer Driver | No | 88 | 0.0948275862068965 | 408 | 46 | 0.0495689655172413 | 0 |
| KSR2-201 | KSR2 | Q6VAB6 | Kinase suppressor of Ras 2 | chr12 | GO:0007265 | Not Cancer Driver | No | 192 | 0.2021052631578947 | 428 | 102 | 0.1073684210526315 | 0 |
| LAT-201 | LAT | O43561 | Linker for activation of T-cells family member 1 | chr16 | GO:0007265 | Not Cancer Driver | No | 20 | 0.0763358778625954 | 213 | 19 | 0.0725190839694656 | 0 |
| MAPKAPK5-207 | MAPKAPK5 | Q8IW41 | MAP kinase-activated protein kinase 5 | chr12 | GO:0007265 | Not Cancer Driver | No | 38 | 0.080338266384778 | 101 | 6 | 0.0126849894291754 | 0 |
| MRAS-202 | MRAS | O14807 | Ras-related protein M-Ras | chr3 | GO:0007265 | Not Cancer Driver | No | 17 | 0.0817307692307692 | 50 | 10 | 0.048076923076923 | 3 |
| NF1-202 | NF1 | P21359 | Neurofibromin | chr17 | GO:0007265 | Census, Compendium | Yes | 285 | 0.1003874603733709 | 406 | 36 | 0.0126805213103205 | 75 |
| NRAS-201 | NRAS | P01111 | GTPase NRas | chr1 | GO:0007265 | Census, Compendium | Yes | 272 | 1.439153439153439 | 10 | 0 | 0.0 | 12 |
| NTN1-201 | NTN1 | O95631 | Netrin-1 | chr17 | GO:0007265 | Not Cancer Driver | No | 43 | 0.0711920529801324 | 66 | 2 | 0.0033112582781456 | 1 |
| PARK7-201 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | GO:0007265 | Not Cancer Driver | No | 8 | 0.0423280423280423 | 30 | 0 | 0.0 | 6 |
| PLCE1-202 | PLCE1 | Q9P212 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 | chr10 | GO:0007265 | Not Cancer Driver | No | 267 | 0.1159860990443093 | 785 | 79 | 0.0343179843614248 | 1 |
| PLD1-201 | PLD1 | Q13393 | Phospholipase D1 | chr3 | GO:0007265 | Not Cancer Driver | No | 126 | 0.1173184357541899 | 133 | 21 | 0.0195530726256983 | 1 |
| PLK2-201 | PLK2 | Q9NYY3 | Serine/threonine-protein kinase PLK2 | chr5 | GO:0007265 | Not Cancer Driver | No | 55 | 0.0802919708029197 | 180 | 18 | 0.0262773722627737 | 0 |
| RABGEF1-201 | RABGEF1 | Q9UJ41 | Rab5 GDP/GTP exchange factor | chr7 | GO:0007265 | Not Cancer Driver | No | 59 | 0.120162932790224 | 175 | 27 | 0.054989816700611 | 0 |
| RALA-201 | RALA | P11233 | Ras-related protein Ral-A | chr7 | GO:0007265 | Not Cancer Driver | No | 29 | 0.1407766990291262 | 34 | 3 | 0.0145631067961165 | 4 |
| RALB-201 | RALB | P11234 | Ras-related protein Ral-B | chr2 | GO:0007265 | Not Cancer Driver | No | 29 | 0.1407766990291262 | 35 | 4 | 0.0194174757281553 | 0 |
| RALGDS-202 | RALGDS | Q12967 | Ral guanine nucleotide dissociation stimulator | chr9 | GO:0007265 | Census, Compendium | Yes | 72 | 0.0787746170678337 | 382 | 28 | 0.0306345733041575 | 0 |
| RALGPS1-201 | RALGPS1 | Q5JS13 | Ras-specific guanine nucleotide-releasing factor RalGPS1 | chr9 | GO:0007265 | Not Cancer Driver | No | 40 | 0.0718132854578097 | 219 | 19 | 0.0341113105924596 | 0 |
| RALGPS2-204 | RALGPS2 | Q86X27 | Ras-specific guanine nucleotide-releasing factor RalGPS2 | chr1 | GO:0007265 | Not Cancer Driver | No | 67 | 0.1149228130360205 | 184 | 17 | 0.0291595197255574 | 0 |
| RAPGEF1-201 | RAPGEF1 | Q13905 | Rap guanine nucleotide exchange factor 1 | chr9 | GO:0007265 | Not Cancer Driver | No | 119 | 0.1104921077065923 | 588 | 66 | 0.0612813370473537 | 0 |
| RAPGEF2-201 | RAPGEF2 | Q9Y4G8 | Rap guanine nucleotide exchange factor 2 | chr4 | GO:0007265 | Not Cancer Driver | No | 132 | 0.0880587058038692 | 805 | 72 | 0.048032021347565 | 0 |
| RAPGEF3-205 | RAPGEF3 | O95398 | Rap guanine nucleotide exchange factor 3 | chr12 | GO:0007265 | Not Cancer Driver | No | 79 | 0.085590465872156 | 197 | 18 | 0.0195016251354279 | 0 |
| RAPGEF4-201 | RAPGEF4 | Q8WZA2 | Rap guanine nucleotide exchange factor 4 | chr2 | GO:0007265 | Not Cancer Driver | No | 113 | 0.1117705242334322 | 192 | 16 | 0.0158259149357072 | 0 |
| RAPGEF5-202 | RAPGEF5 | Q92565 | Rap guanine nucleotide exchange factor 5 | chr7 | GO:0007265 | Not Cancer Driver | No | 50 | 0.0862068965517241 | 56 | 9 | 0.0155172413793103 | 0 |
| RAPGEF6-208 | RAPGEF6 | Q8TEU7 | Rap guanine nucleotide exchange factor 6 | chr5 | GO:0007265 | Not Cancer Driver | No | 143 | 0.0893191755153029 | 790 | 72 | 0.0449718925671455 | 0 |
| RAPGEFL1-211 | RAPGEFL1 | Q9UHV5 | Rap guanine nucleotide exchange factor-like 1 | chr17 | GO:0007265 | Not Cancer Driver | No | 36 | 0.0543806646525679 | 201 | 2 | 0.0030211480362537 | 0 |
| RASGEF1A-204 | RASGEF1A | Q8N9B8 | Ras-GEF domain-containing family member 1A | chr10 | GO:0007265 | Not Cancer Driver | No | 48 | 0.0997920997920998 | 67 | 10 | 0.0207900207900207 | 0 |
| RASGEF1B-201 | RASGEF1B | Q0VAM2 | Ras-GEF domain-containing family member 1B | chr4 | GO:0007265 | Not Cancer Driver | No | 43 | 0.0909090909090909 | 27 | 3 | 0.0063424947145877 | 0 |
| RASGEF1C-201 | RASGEF1C | Q8N431 | Ras-GEF domain-containing family member 1C | chr5 | GO:0007265 | Not Cancer Driver | No | 65 | 0.1394849785407725 | 62 | 9 | 0.01931330472103 | 0 |
| RASGRF1-202 | RASGRF1 | Q13972 | Ras-specific guanine nucleotide-releasing factor 1 | chr15 | GO:0007265 | Not Cancer Driver | No | 169 | 0.1327572663000785 | 333 | 53 | 0.0416339355852317 | 0 |
| RASGRF2-201 | RASGRF2 | O14827 | Ras-specific guanine nucleotide-releasing factor 2 | chr5 | GO:0007265 | Not Cancer Driver | No | 158 | 0.1277283751010509 | 276 | 42 | 0.0339531123686337 | 0 |
| RASGRP1-201 | RASGRP1 | O95267 | RAS guanyl-releasing protein 1 | chr15 | GO:0007265 | Not Cancer Driver | No | 70 | 0.0878293601003764 | 192 | 11 | 0.013801756587202 | 1 |
| RASGRP2-211 | RASGRP2 | Q7LDG7 | RAS guanyl-releasing protein 2 | chr11 | GO:0007265 | Not Cancer Driver | No | 76 | 0.1247947454844006 | 88 | 11 | 0.0180623973727422 | 4 |
| RASGRP3-202 | RASGRP3 | Q8IV61 | Ras guanyl-releasing protein 3 | chr2 | GO:0007265 | Not Cancer Driver | No | 89 | 0.1289855072463768 | 148 | 14 | 0.0202898550724637 | 0 |
| RASGRP4-214 | RASGRP4 | Q8TDF6 | RAS guanyl-releasing protein 4 | chr19 | GO:0007265 | Not Cancer Driver | No | 70 | 0.1040118870728083 | 180 | 34 | 0.050520059435364 | 0 |
| RASSF1-202 | RASSF1 | Q9NS23 | Ras association domain-containing protein 1 | chr3 | GO:0007265 | Not Cancer Driver | No | 21 | 0.0610465116279069 | 79 | 2 | 0.005813953488372 | 0 |
| RB1-201 | RB1 | P06400 | Retinoblastoma-associated protein | chr13 | GO:0007265 | Census, Compendium | Yes | 89 | 0.0959051724137931 | 282 | 26 | 0.0280172413793103 | 21 |
| RFXANK-201 | RFXANK | O14593 | DNA-binding protein RFXANK | chr19 | GO:0007265 | Not Cancer Driver | No | 13 | 0.05 | 122 | 4 | 0.0153846153846153 | 1 |
| RGL1-202 | RGL1 | Q9NZL6 | Ral guanine nucleotide dissociation stimulator-like 1 | chr1 | GO:0007265 | Not Cancer Driver | No | 81 | 0.10546875 | 296 | 34 | 0.0442708333333333 | 0 |
| RGL2-247 | RGL2 | O15211 | Ral guanine nucleotide dissociation stimulator-like 2 | chr6 | GO:0007265 | Not Cancer Driver | No | 67 | 0.0862290862290862 | 461 | 38 | 0.0489060489060489 | 0 |
| RGL3-201 | RGL3 | Q3MIN7 | Ral guanine nucleotide dissociation stimulator-like 3 | chr19 | GO:0007265 | Compendium | Yes | 42 | 0.0591549295774647 | 401 | 22 | 0.0309859154929577 | 0 |
| RGL4-201 | RGL4 | Q8IZJ4 | Ral-GDS-related protein | chr22 | GO:0007265 | Not Cancer Driver | No | 46 | 0.0972515856236786 | 177 | 18 | 0.0380549682875264 | 0 |
| RIT1-202 | RIT1 | Q92963 | GTP-binding protein Rit1 | chr1 | GO:0007265 | Not Cancer Driver | No | 30 | 0.136986301369863 | 44 | 2 | 0.0091324200913242 | 9 |
| RIT2-201 | RIT2 | Q99578 | GTP-binding protein Rit2 | chr18 | GO:0007265 | Not Cancer Driver | No | 61 | 0.2811059907834101 | 31 | 13 | 0.0599078341013824 | 0 |
| RRAS-201 | RRAS | P10301 | Ras-related protein R-Ras | chr19 | GO:0007265 | Not Cancer Driver | No | 19 | 0.0871559633027523 | 71 | 4 | 0.018348623853211 | 0 |
| RRAS2-201 | RRAS2 | P62070 | Ras-related protein R-Ras2 | chr11 | GO:0007265 | Compendium | Yes | 27 | 0.1323529411764706 | 37 | 1 | 0.0049019607843137 | 3 |
| SDCBP-201 | SDCBP | O00560 | Syntenin-1 | chr8 | GO:0007265 | Not Cancer Driver | No | 23 | 0.0771812080536912 | 17 | 1 | 0.0033557046979865 | 0 |
| SHOC2-202 | SHOC2 | Q9UQ13 | Leucine-rich repeat protein SHOC-2 | chr10 | GO:0007265 | Not Cancer Driver | No | 38 | 0.0652920962199312 | 110 | 9 | 0.0154639175257731 | 2 |
| SHTN1-202 | SHTN1 | A0MZ66 | Shootin-1 | chr10 | GO:0007265 | Census | Yes | 52 | 0.0824088748019017 | 471 | 42 | 0.0665610142630744 | 0 |
| SOS1-202 | SOS1 | Q07889 | Son of sevenless homolog 1 | chr2 | GO:0007265 | Compendium | Yes | 155 | 0.1162790697674418 | 459 | 47 | 0.0352588147036759 | 32 |
| SOS2-201 | SOS2 | Q07890 | Son of sevenless homolog 2 | chr14 | GO:0007265 | Not Cancer Driver | No | 123 | 0.0923423423423423 | 362 | 44 | 0.033033033033033 | 2 |
| SYNGAP1-229 | SYNGAP1 | Q96PV0 | Ras/Rap GTPase-activating protein SynGAP | chr6 | GO:0007265 | Not Cancer Driver | No | 113 | 0.0841399851079672 | 833 | 66 | 0.0491437081161578 | 4 |
| TP53-201 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0007265 | Census, Compendium | Yes | 2742 | 6.977099236641221 | 282 | 1364 | 3.470737913486005 | 60 |
| USP50-203 | USP50 | Q70EL3 | Inactive ubiquitin carboxyl-terminal hydrolase 50 | chr15 | GO:0007265 | Not Cancer Driver | No | 24 | 0.0718562874251497 | 2 | 0 | 0.0 | 0 |
| USP8-201 | USP8 | P40818 | Ubiquitin carboxyl-terminal hydrolase 8 | chr15 | GO:0007265 | Census, Compendium | Yes | 82 | 0.073345259391771 | 603 | 49 | 0.0438282647584973 | 0 |