Total number of protein in "GO:0007275" GO term: 79
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ALK-201 | ALK | Q9UM73 | ALK tyrosine kinase receptor | chr2 | GO:0007275 | Census, Compendium | Yes | 233 | 0.1438271604938271 | 577 | 79 | 0.0487654320987654 | 12 |
AXL-201 | AXL | P30530 | Tyrosine-protein kinase receptor UFO | chr19 | GO:0007275 | Not Cancer Driver | No | 131 | 0.1465324384787472 | 342 | 51 | 0.0570469798657718 | 0 |
CDH1-201 | CDH1 | P12830 | Cadherin-1 | chr16 | GO:0007275 | Census, Compendium | Yes | 125 | 0.1417233560090703 | 401 | 70 | 0.0793650793650793 | 5 |
CDH10-201 | CDH10 | Q9Y6N8 | Cadherin-10 | chr5 | GO:0007275 | Census, Compendium | Yes | 410 | 0.5203045685279187 | 287 | 149 | 0.1890862944162436 | 0 |
CDH11-201 | CDH11 | P55287 | Cadherin-11 | chr16 | GO:0007275 | Census, Compendium | Yes | 220 | 0.2763819095477386 | 401 | 102 | 0.1281407035175879 | 8 |
CDH12-201 | CDH12 | P55289 | Cadherin-12 | chr5 | GO:0007275 | Not Cancer Driver | No | 299 | 0.3765743073047859 | 265 | 80 | 0.1007556675062972 | 0 |
CDH13-209 | CDH13 | P55290 | Cadherin-13 | chr16 | GO:0007275 | Not Cancer Driver | No | 128 | 0.1795231416549789 | 236 | 47 | 0.0659186535764375 | 0 |
CDH15-201 | CDH15 | P55291 | Cadherin-15 | chr16 | GO:0007275 | Not Cancer Driver | No | 86 | 0.1056511056511056 | 405 | 48 | 0.0589680589680589 | 3 |
CDH17-201 | CDH17 | Q12864 | Cadherin-17 | chr8 | GO:0007275 | Census | Yes | 131 | 0.157451923076923 | 188 | 27 | 0.032451923076923 | 0 |
CDH18-202 | CDH18 | Q13634 | Cadherin-18 | chr5 | GO:0007275 | Not Cancer Driver | No | 309 | 0.3911392405063291 | 325 | 133 | 0.1683544303797468 | 0 |
CDH19-201 | CDH19 | Q9H159 | Cadherin-19 | chr18 | GO:0007275 | Not Cancer Driver | No | 157 | 0.2033678756476684 | 176 | 35 | 0.0453367875647668 | 0 |
CDH2-201 | CDH2 | P19022 | Cadherin-2 | chr18 | GO:0007275 | Not Cancer Driver | No | 182 | 0.2008830022075055 | 464 | 107 | 0.1181015452538631 | 7 |
CDH20-201 | CDH20 | Q9HBT6 | Cadherin-20 | chr18 | GO:0007275 | Not Cancer Driver | No | 170 | 0.212234706616729 | 216 | 44 | 0.0549313358302122 | 0 |
CDH22-202 | CDH22 | Q9UJ99 | Cadherin-22 | chr20 | GO:0007275 | Not Cancer Driver | No | 120 | 0.144927536231884 | 410 | 43 | 0.0519323671497584 | 0 |
CDH24-201 | CDH24 | Q86UP0 | Cadherin-24 | chr14 | GO:0007275 | Not Cancer Driver | No | 74 | 0.0903540903540903 | 439 | 39 | 0.0476190476190476 | 0 |
CDH26-202 | CDH26 | Q8IXH8 | Cadherin-like protein 26 | chr20 | GO:0007275 | Not Cancer Driver | No | 124 | 0.1490384615384615 | 299 | 45 | 0.0540865384615384 | 0 |
CDH3-201 | CDH3 | P22223 | Cadherin-3 | chr16 | GO:0007275 | Not Cancer Driver | No | 65 | 0.0784077201447527 | 493 | 40 | 0.0482509047044632 | 2 |
CDH4-203 | CDH4 | P55283 | Cadherin-4 | chr20 | GO:0007275 | Not Cancer Driver | No | 222 | 0.2423580786026201 | 443 | 130 | 0.1419213973799126 | 0 |
CDH5-201 | CDH5 | P33151 | Cadherin-5 | chr16 | GO:0007275 | Not Cancer Driver | No | 121 | 0.1543367346938775 | 305 | 44 | 0.0561224489795918 | 0 |
CDH6-201 | CDH6 | P55285 | Cadherin-6 | chr5 | GO:0007275 | Not Cancer Driver | No | 216 | 0.2734177215189873 | 339 | 94 | 0.1189873417721519 | 0 |
CDH7-202 | CDH7 | Q9ULB5 | Cadherin-7 | chr18 | GO:0007275 | Not Cancer Driver | No | 227 | 0.289171974522293 | 263 | 80 | 0.1019108280254777 | 0 |
CDH8-203 | CDH8 | P55286 | Cadherin-8 | chr16 | GO:0007275 | Not Cancer Driver | No | 291 | 0.3642052565707134 | 244 | 83 | 0.1038798498122653 | 0 |
CDH9-201 | CDH9 | Q9ULB4 | Cadherin-9 | chr5 | GO:0007275 | Not Cancer Driver | No | 346 | 0.4385297845373891 | 298 | 149 | 0.1888466413181242 | 0 |
CDHR3-201 | CDHR3 | Q6ZTQ4 | Cadherin-related family member 3 | chr7 | GO:0007275 | Not Cancer Driver | No | 109 | 0.1231638418079096 | 206 | 25 | 0.0282485875706214 | 0 |
CSF1R-210 | CSF1R | P07333 | Macrophage colony-stimulating factor 1 receptor | chr5 | GO:0007275 | Census | Yes | 101 | 0.1039094650205761 | 124 | 12 | 0.0123456790123456 | 20 |
DDR1-225 | DDR1 | Q08345 | Epithelial discoidin domain-containing receptor 1 | chr6 | GO:0007275 | Not Cancer Driver | No | 98 | 0.1073384446878422 | 253 | 41 | 0.044906900328587 | 0 |
DDR2-201 | DDR2 | Q16832 | Discoidin domain-containing receptor 2 | chr1 | GO:0007275 | Census | Yes | 129 | 0.1508771929824561 | 120 | 25 | 0.0292397660818713 | 7 |
EGFR-201 | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:0007275 | Census, Compendium | Yes | 346 | 0.2859504132231405 | 223 | 30 | 0.024793388429752 | 1 |
EPHA1-201 | EPHA1 | P21709 | Ephrin type-A receptor 1 | chr7 | GO:0007275 | Not Cancer Driver | No | 109 | 0.1116803278688524 | 211 | 29 | 0.0297131147540983 | 0 |
EPHA2-201 | EPHA2 | P29317 | Ephrin type-A receptor 2 | chr1 | GO:0007275 | Compendium | Yes | 147 | 0.1506147540983606 | 188 | 33 | 0.033811475409836 | 3 |
EPHB4-201 | EPHB4 | P54760 | Ephrin type-B receptor 4 | chr7 | GO:0007275 | Not Cancer Driver | No | 101 | 0.1023302938196555 | 186 | 18 | 0.0182370820668693 | 11 |
ERBB2-201 | ERBB2 | P04626 | Receptor tyrosine-protein kinase erbB-2 | chr17 | GO:0007275 | Census, Compendium | Yes | 249 | 0.198406374501992 | 315 | 32 | 0.0254980079681274 | 1 |
ERBB3-201 | ERBB3 | P21860 | Receptor tyrosine-protein kinase erbB-3 | chr12 | GO:0007275 | Census, Compendium | Yes | 265 | 0.1974664679582712 | 398 | 59 | 0.0439642324888226 | 3 |
ERBB4-202 | ERBB4 | Q15303 | Receptor tyrosine-protein kinase erbB-4 | chr2 | GO:0007275 | Census, Compendium | Yes | 376 | 0.2874617737003058 | 324 | 95 | 0.0726299694189602 | 2 |
FGFR1-214 | FGFR1 | P11362 | Fibroblast growth factor receptor 1 | chr8 | GO:0007275 | Census, Compendium | Yes | 92 | 0.1119221411192214 | 231 | 26 | 0.0316301703163017 | 69 |
FGFR2-206 | FGFR2 | P21802 | Fibroblast growth factor receptor 2 | chr10 | GO:0007275 | Census, Compendium | Yes | 193 | 0.2350791717417783 | 229 | 34 | 0.0414129110840438 | 57 |
FGFR3-205 | FGFR3 | P22607 | Fibroblast growth factor receptor 3 | chr4 | GO:0007275 | Census, Compendium | Yes | 134 | 0.1662531017369727 | 241 | 18 | 0.0223325062034739 | 32 |
FGFR4-201 | FGFR4 | P22455 | Fibroblast growth factor receptor 4 | chr5 | GO:0007275 | Census, Compendium | Yes | 101 | 0.1259351620947631 | 163 | 27 | 0.0336658354114713 | 0 |
FLT1-201 | FLT1 | P17948 | Vascular endothelial growth factor receptor 1 | chr13 | GO:0007275 | Not Cancer Driver | No | 212 | 0.1584454409566517 | 103 | 17 | 0.0127055306427503 | 0 |
FLT3-201 | FLT3 | P36888 | Receptor-type tyrosine-protein kinase FLT3 | chr13 | GO:0007275 | Census, Compendium | Yes | 153 | 0.1540785498489426 | 64 | 19 | 0.0191339375629405 | 0 |
FLT4-201 | FLT4 | P35916 | Vascular endothelial growth factor receptor 3 | chr5 | GO:0007275 | Census, Compendium | Yes | 203 | 0.1489361702127659 | 259 | 33 | 0.0242112986060161 | 14 |
FST-201 | FST | P19883 | Follistatin | chr5 | GO:0007275 | Not Cancer Driver | No | 33 | 0.0959302325581395 | 20 | 3 | 0.0087209302325581 | 0 |
FSTL1-201 | FSTL1 | Q12841 | Follistatin-related protein 1 | chr3 | GO:0007275 | Not Cancer Driver | No | 36 | 0.1168831168831168 | 51 | 5 | 0.0162337662337662 | 0 |
FSTL3-201 | FSTL3 | O95633 | Follistatin-related protein 3 | chr19 | GO:0007275 | Census | Yes | 15 | 0.0570342205323193 | 28 | 1 | 0.0038022813688212 | 0 |
FSTL4-201 | FSTL4 | Q6MZW2 | Follistatin-related protein 4 | chr5 | GO:0007275 | Not Cancer Driver | No | 100 | 0.1187648456057007 | 96 | 9 | 0.010688836104513 | 0 |
FSTL5-201 | FSTL5 | Q8N475 | Follistatin-related protein 5 | chr4 | GO:0007275 | Not Cancer Driver | No | 266 | 0.3140495867768595 | 46 | 15 | 0.0177095631641086 | 0 |
GCNT2-216 | GCNT2 | Q8N0V5 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase | chr6 | GO:0007275 | Not Cancer Driver | No | 27 | 0.0671641791044776 | 3 | 0 | 0.0 | 0 |
GREB1-204 | GREB1 | Q4ZG55 | Protein GREB1 | chr2 | GO:0007275 | Not Cancer Driver | No | 251 | 0.1287839917906618 | 375 | 54 | 0.0277065161621344 | 0 |
GREB1L-202 | GREB1L | Q9C091 | GREB1-like protein | chr18 | GO:0007275 | Not Cancer Driver | No | 57 | 0.0296411856474258 | 480 | 13 | 0.0067602704108164 | 24 |
IGF1R-217 | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | GO:0007275 | Not Cancer Driver | No | 143 | 0.1046086320409656 | 265 | 30 | 0.021945866861741 | 6 |
INSR-201 | INSR | P06213 | Insulin receptor | chr19 | GO:0007275 | Not Cancer Driver | No | 139 | 0.1005788712011577 | 282 | 37 | 0.0267727930535455 | 63 |
INSRR-201 | INSRR | P14616 | Insulin receptor-related protein | chr1 | GO:0007275 | Not Cancer Driver | No | 213 | 0.164225134926754 | 229 | 34 | 0.0262143407864302 | 0 |
KDR-201 | KDR | P35968 | Vascular endothelial growth factor receptor 2 | chr4 | GO:0007275 | Census, Compendium | Yes | 276 | 0.2035398230088495 | 276 | 40 | 0.0294985250737463 | 2 |
KIT-201 | KIT | P10721 | Mast/stem cell growth factor receptor Kit | chr4 | GO:0007275 | Census, Compendium | Yes | 186 | 0.1905737704918032 | 84 | 24 | 0.0245901639344262 | 15 |
KREMEN1-203 | KREMEN1 | Q96MU8 | Kremen protein 1 | chr22 | GO:0007275 | Not Cancer Driver | No | 55 | 0.1162790697674418 | 73 | 6 | 0.0126849894291754 | 1 |
KREMEN2-201 | KREMEN2 | Q8NCW0 | Kremen protein 2 | chr16 | GO:0007275 | Not Cancer Driver | No | 17 | 0.0367965367965368 | 139 | 2 | 0.0043290043290043 | 0 |
LEPR-202 | LEPR | P48357 | Leptin receptor | chr1 | GO:0007275 | Not Cancer Driver | No | 178 | 0.1527896995708154 | 57 | 10 | 0.0085836909871244 | 0 |
LTK-201 | LTK | P29376 | Leukocyte tyrosine kinase receptor | chr15 | GO:0007275 | Not Cancer Driver | No | 63 | 0.0729166666666666 | 301 | 17 | 0.0196759259259259 | 0 |
MERTK-201 | MERTK | Q12866 | Tyrosine-protein kinase Mer | chr2 | GO:0007275 | Not Cancer Driver | No | 134 | 0.1341341341341341 | 161 | 25 | 0.025025025025025 | 3 |
MET-202 | MET | P08581 | Hepatocyte growth factor receptor | chr7 | GO:0007275 | Census, Compendium | Yes | 161 | 0.1158273381294964 | 62 | 10 | 0.0071942446043165 | 16 |
MST1R-201 | MST1R | Q04912 | Macrophage-stimulating protein receptor | chr3 | GO:0007275 | Not Cancer Driver | No | 147 | 0.105 | 183 | 24 | 0.0171428571428571 | 1 |
MUSK-204 | MUSK | O15146 | Muscle, skeletal receptor tyrosine-protein kinase | chr9 | GO:0007275 | Not Cancer Driver | No | 145 | 0.1668584579976985 | 35 | 7 | 0.0080552359033371 | 7 |
NTRK1-206 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | GO:0007275 | Census, Compendium | Yes | 133 | 0.1670854271356784 | 57 | 8 | 0.0100502512562814 | 23 |
NTRK2-246 | NTRK2 | Q16620 | BDNF/NT-3 growth factors receptor | chr9 | GO:0007275 | Not Cancer Driver | No | 103 | 0.1253041362530413 | 117 | 14 | 0.0170316301703163 | 1 |
NTRK3-217 | NTRK3 | Q16288 | NT-3 growth factor receptor | chr15 | GO:0007275 | Census, Compendium | Yes | 214 | 0.2550655542312277 | 56 | 15 | 0.0178784266984505 | 3 |
PDGFRA-201 | PDGFRA | P16234 | Platelet-derived growth factor receptor alpha | chr4 | GO:0007275 | Census, Compendium | Yes | 213 | 0.1955922865013774 | 173 | 36 | 0.0330578512396694 | 2 |
PDGFRB-201 | PDGFRB | P09619 | Platelet-derived growth factor receptor beta | chr5 | GO:0007275 | Census, Compendium | Yes | 134 | 0.1211573236889692 | 233 | 40 | 0.0361663652802893 | 7 |
PTCD2-202 | PTCD2 | Q8WV60 | Pentatricopeptide repeat-containing protein 2, mitochondrial | chr5 | GO:0007275 | Not Cancer Driver | No | 31 | 0.0798969072164948 | 9 | 0 | 0.0 | 0 |
RET-202 | RET | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret | chr10 | GO:0007275 | Census, Compendium | Yes | 176 | 0.1579892280071813 | 108 | 11 | 0.0098743267504488 | 91 |
ROR1-201 | ROR1 | Q01973 | Inactive tyrosine-protein kinase transmembrane receptor ROR1 | chr1 | GO:0007275 | Not Cancer Driver | No | 113 | 0.1205976520811099 | 281 | 37 | 0.03948772678762 | 1 |
ROR2-201 | ROR2 | Q01974 | Tyrosine-protein kinase transmembrane receptor ROR2 | chr9 | GO:0007275 | Not Cancer Driver | No | 164 | 0.1739130434782608 | 304 | 58 | 0.0615058324496288 | 5 |
ROS1-202 | ROS1 | P08922 | Proto-oncogene tyrosine-protein kinase ROS | chr6 | GO:0007275 | Census | Yes | 356 | 0.1516829995739241 | 197 | 45 | 0.0191734128674904 | 0 |
RYK-208 | RYK | P34925 | Tyrosine-protein kinase RYK | chr3 | GO:0007275 | Not Cancer Driver | No | 38 | 0.0626029654036243 | 85 | 3 | 0.0049423393739703 | 0 |
SPINK5-201 | SPINK5 | Q9NQ38 | Serine protease inhibitor Kazal-type 5 | chr5 | GO:0007275 | Not Cancer Driver | No | 129 | 0.1212406015037594 | 601 | 90 | 0.0845864661654135 | 0 |
TEK-201 | TEK | Q02763 | Angiopoietin-1 receptor | chr9 | GO:0007275 | Not Cancer Driver | No | 145 | 0.1290035587188612 | 126 | 13 | 0.0115658362989323 | 9 |
TIE1-201 | TIE1 | P35590 | Tyrosine-protein kinase receptor Tie-1 | chr1 | GO:0007275 | Not Cancer Driver | No | 156 | 0.1370826010544815 | 223 | 36 | 0.031634446397188 | 0 |
TMEFF2-201 | TMEFF2 | Q9UIK5 | Tomoregulin-2 | chr2 | GO:0007275 | Not Cancer Driver | No | 64 | 0.1711229946524064 | 68 | 5 | 0.0133689839572192 | 0 |
TYRO3-201 | TYRO3 | Q06418 | Tyrosine-protein kinase receptor TYRO3 | chr15 | GO:0007275 | Not Cancer Driver | No | 86 | 0.096629213483146 | 197 | 18 | 0.0202247191011235 | 0 |
VDR-206 | VDR | P11473 | Vitamin D3 receptor | chr12 | GO:0007275 | Not Cancer Driver | No | 36 | 0.0843091334894613 | 102 | 7 | 0.0163934426229508 | 14 |