Total number of protein in "GO:0007409" GO term: 96
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACTB-217 | ACTB | P60709 | Actin, cytoplasmic 1 | chr7 | GO:0007409 | Not Cancer Driver | No | 96 | 0.256 | 43 | 5 | 0.0133333333333333 | 4 |
ACTBL2-201 | ACTBL2 | Q562R1 | Beta-actin-like protein 2 | chr5 | GO:0007409 | Not Cancer Driver | No | 60 | 0.1595744680851064 | 29 | 3 | 0.0079787234042553 | 0 |
ACTG1-205 | ACTG1 | P63261 | Actin, cytoplasmic 2 | chr17 | GO:0007409 | Not Cancer Driver | No | 67 | 0.1786666666666666 | 42 | 11 | 0.0293333333333333 | 15 |
ACTL9-201 | ACTL9 | Q8TC94 | Actin-like protein 9 | chr19 | GO:0007409 | Not Cancer Driver | No | 97 | 0.2331730769230769 | 101 | 14 | 0.0336538461538461 | 0 |
ADCY1-201 | ADCY1 | Q08828 | Adenylate cyclase type 1 | chr7 | GO:0007409 | Not Cancer Driver | No | 176 | 0.1572832886505809 | 100 | 16 | 0.0142984807864164 | 0 |
ADGRB1-201 | ADGRB1 | O14514 | Adhesion G protein-coupled receptor B1 | chr8 | GO:0007409 | Compendium | Yes | 170 | 0.1073232323232323 | 487 | 39 | 0.0246212121212121 | 0 |
AFG3L2-201 | AFG3L2 | Q9Y4W6 | AFG3-like protein 2 | chr18 | GO:0007409 | Not Cancer Driver | No | 38 | 0.0476787954830614 | 162 | 5 | 0.0062735257214554 | 17 |
AMIGO1-202 | AMIGO1 | Q86WK6 | Amphoterin-induced protein 1 | chr1 | GO:0007409 | Not Cancer Driver | No | 37 | 0.075050709939148 | 85 | 5 | 0.0101419878296146 | 0 |
ANK3-201 | ANK3 | Q12955 | Ankyrin-3 | chr10 | GO:0007409 | Not Cancer Driver | No | 652 | 0.1489604752113319 | 3069 | 442 | 0.1009824080420379 | 0 |
APBB1-220 | APBB1 | O00213 | Amyloid beta precursor protein binding family B member 1 | chr11 | GO:0007409 | Not Cancer Driver | No | 80 | 0.1126760563380281 | 400 | 43 | 0.0605633802816901 | 0 |
APLP1-212 | APLP1 | P51693 | Amyloid beta precursor like protein 1 | chr19 | GO:0007409 | Not Cancer Driver | No | 112 | 0.1723076923076923 | 455 | 77 | 0.1184615384615384 | 0 |
APLP2-226 | APLP2 | Q06481 | Amyloid beta precursor like protein 2 | chr11 | GO:0007409 | Not Cancer Driver | No | 68 | 0.0891218872870249 | 393 | 32 | 0.0419397116644823 | 0 |
APP-201 | APP | P05067 | Amyloid-beta precursor protein | chr21 | GO:0007409 | Not Cancer Driver | No | 94 | 0.122077922077922 | 419 | 52 | 0.0675324675324675 | 12 |
ATL1-201 | ATL1 | Q8WXF7 | Atlastin-1 | chr14 | GO:0007409 | Not Cancer Driver | No | 45 | 0.0806451612903225 | 55 | 7 | 0.0125448028673835 | 18 |
ATP8A2-203 | ATP8A2 | Q9NTI2 | Phospholipid-transporting ATPase IB | chr13 | GO:0007409 | Not Cancer Driver | No | 165 | 0.1388888888888889 | 78 | 8 | 0.0067340067340067 | 1 |
BAIAP2-202 | BAIAP2 | Q9UQB8 | Brain-specific angiogenesis inhibitor 1-associated protein 2 | chr17 | GO:0007409 | Not Cancer Driver | No | 60 | 0.108695652173913 | 332 | 43 | 0.0778985507246376 | 0 |
BCL2-201 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:0007409 | Census, Compendium | Yes | 21 | 0.0878661087866108 | 73 | 5 | 0.0209205020920502 | 0 |
BRSK1-201 | BRSK1 | Q8TDC3 | Serine/threonine-protein kinase BRSK1 | chr19 | GO:0007409 | Not Cancer Driver | No | 92 | 0.1182519280205655 | 461 | 53 | 0.0681233933161953 | 0 |
BRSK2-208 | BRSK2 | Q8IWQ3 | Serine/threonine-protein kinase BRSK2 | chr11 | GO:0007409 | Not Cancer Driver | No | 58 | 0.0788043478260869 | 321 | 23 | 0.03125 | 0 |
CCK-202 | CCK | P06307 | Cholecystokinin | chr3 | GO:0007409 | Not Cancer Driver | No | 23 | 0.2 | 68 | 10 | 0.0869565217391304 | 0 |
CCKAR-201 | CCKAR | P32238 | Cholecystokinin receptor type A | chr4 | GO:0007409 | Not Cancer Driver | No | 84 | 0.1962616822429906 | 49 | 11 | 0.0257009345794392 | 0 |
CDK5-204 | CDK5 | Q00535 | Cyclin-dependent kinase 5 | chr7 | GO:0007409 | Not Cancer Driver | No | 38 | 0.1301369863013698 | 5 | 0 | 0.0 | 0 |
CNP-202 | CNP | P09543 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | chr17 | GO:0007409 | Not Cancer Driver | No | 21 | 0.0498812351543943 | 71 | 1 | 0.002375296912114 | 0 |
CNTN4-203 | CNTN4 | Q8IWV2 | Contactin-4 | chr3 | GO:0007409 | Not Cancer Driver | No | 247 | 0.2407407407407407 | 303 | 72 | 0.0701754385964912 | 0 |
CNTNAP1-201 | CNTNAP1 | P78357 | Contactin-associated protein 1 | chr17 | GO:0007409 | Not Cancer Driver | No | 131 | 0.0946531791907514 | 141 | 15 | 0.0108381502890173 | 6 |
CREB1-201 | CREB1 | P16220 | Cyclic AMP-responsive element-binding protein 1 | chr2 | GO:0007409 | Census | Yes | 14 | 0.0428134556574923 | 278 | 13 | 0.0397553516819571 | 0 |
CTNNA2-203 | CTNNA2 | P26232 | Catenin alpha-2 | chr2 | GO:0007409 | Census | Yes | 328 | 0.3441762854144806 | 308 | 108 | 0.1133263378803777 | 0 |
DAB1-203 | DAB1 | O75553 | Disabled homolog 1 | chr1 | GO:0007409 | Not Cancer Driver | No | 158 | 0.2687074829931973 | 393 | 111 | 0.1887755102040816 | 0 |
DCC-202 | DCC | P43146 | Netrin receptor DCC | chr18 | GO:0007409 | Census, Compendium | Yes | 447 | 0.308914996544575 | 632 | 192 | 0.1326883206634416 | 2 |
DOCK7-219 | DOCK7 | Q96N67 | Dedicator of cytokinesis protein 7 | chr1 | GO:0007409 | Not Cancer Driver | No | 183 | 0.0855140186915887 | 455 | 33 | 0.0154205607476635 | 0 |
DRD2-202 | DRD2 | P14416 | D(2) dopamine receptor | chr11 | GO:0007409 | Not Cancer Driver | No | 91 | 0.2054176072234763 | 124 | 31 | 0.0699774266365688 | 0 |
DSCAML1-205 | DSCAML1 | Q8TD84 | Cell adhesion molecule DSCAML1 | chr11 | GO:0007409 | Not Cancer Driver | No | 358 | 0.1743789576229907 | 742 | 138 | 0.0672187043351193 | 0 |
FGFR2-206 | FGFR2 | P21802 | Fibroblast growth factor receptor 2 | chr10 | GO:0007409 | Census, Compendium | Yes | 193 | 0.2350791717417783 | 229 | 34 | 0.0414129110840438 | 57 |
FLOT1-201 | FLOT1 | O75955 | Flotillin-1 | chr6 | GO:0007409 | Not Cancer Driver | No | 31 | 0.072599531615925 | 122 | 10 | 0.0234192037470726 | 0 |
IGF1R-217 | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | GO:0007409 | Not Cancer Driver | No | 143 | 0.1046086320409656 | 265 | 30 | 0.021945866861741 | 6 |
ISL1-201 | ISL1 | P61371 | Insulin gene enhancer protein ISL-1 | chr5 | GO:0007409 | Not Cancer Driver | No | 73 | 0.2091690544412607 | 181 | 41 | 0.1174785100286533 | 0 |
ISL2-201 | ISL2 | Q96A47 | Insulin gene enhancer protein ISL-2 | chr15 | GO:0007409 | Not Cancer Driver | No | 20 | 0.0557103064066852 | 168 | 10 | 0.0278551532033426 | 0 |
KLF7-201 | KLF7 | O75840 | Krueppel-like factor 7 | chr2 | GO:0007409 | Not Cancer Driver | No | 36 | 0.119205298013245 | 72 | 4 | 0.0132450331125827 | 0 |
LLGL1-201 | LLGL1 | Q15334 | Lethal(2) giant larvae protein homolog 1 | chr17 | GO:0007409 | Not Cancer Driver | No | 78 | 0.0733082706766917 | 266 | 9 | 0.0084586466165413 | 0 |
MAP1A-201 | MAP1A | P78559 | Microtubule-associated protein 1A | chr15 | GO:0007409 | Not Cancer Driver | No | 273 | 0.0973956475205137 | 2451 | 234 | 0.0834819835890117 | 0 |
MAP1B-201 | MAP1B | P46821 | Microtubule-associated protein 1B | chr5 | GO:0007409 | Not Cancer Driver | No | 169 | 0.0684764991896272 | 1949 | 166 | 0.0672609400324149 | 0 |
MAP1S-201 | MAP1S | Q66K74 | Microtubule-associated protein 1S | chr19 | GO:0007409 | Not Cancer Driver | No | 85 | 0.0802644003777148 | 529 | 43 | 0.040604343720491 | 0 |
METRN-204 | METRN | Q9UJH8 | Meteorin | chr16 | GO:0007409 | Not Cancer Driver | No | 8 | 0.0273037542662116 | 40 | 1 | 0.0034129692832764 | 0 |
NEFH-201 | NEFH | P12036 | Neurofilament heavy polypeptide | chr22 | GO:0007409 | Compendium | Yes | 16 | 0.0156862745098039 | 866 | 10 | 0.0098039215686274 | 0 |
NEFL-201 | NEFL | P07196 | Neurofilament light polypeptide | chr8 | GO:0007409 | Not Cancer Driver | No | 0 | 0.0 | 285 | 0 | 0.0 | 10 |
NKX2-8-201 | NKX2-8 | O15522 | Homeobox protein Nkx-2.8 | chr14 | GO:0007409 | Not Cancer Driver | No | 13 | 0.0543933054393305 | 163 | 13 | 0.0543933054393305 | 0 |
NRCAM-203 | NRCAM | Q92823 | Neuronal cell adhesion molecule | chr7 | GO:0007409 | Not Cancer Driver | No | 156 | 0.1196319018404908 | 473 | 60 | 0.0460122699386503 | 0 |
NTNG1-205 | NTNG1 | Q9Y2I2 | Netrin-G1 | chr1 | GO:0007409 | Not Cancer Driver | No | 124 | 0.2300556586270872 | 1 | 0 | 0.0 | 0 |
NTNG2-201 | NTNG2 | Q96CW9 | Netrin-G2 | chr9 | GO:0007409 | Not Cancer Driver | No | 73 | 0.1377358490566037 | 8 | 3 | 0.0056603773584905 | 8 |
NUMB-213 | NUMB | P49757 | Protein numb homolog | chr14 | GO:0007409 | Not Cancer Driver | No | 50 | 0.0768049155145929 | 489 | 42 | 0.064516129032258 | 0 |
NUMBL-201 | NUMBL | Q9Y6R0 | Numb-like protein | chr19 | GO:0007409 | Not Cancer Driver | No | 34 | 0.0558292282430213 | 468 | 20 | 0.0328407224958949 | 0 |
PAK3-201 | PAK3 | O75914 | Serine/threonine-protein kinase PAK 3 | chrX | GO:0007409 | Not Cancer Driver | No | 95 | 0.1699463327370304 | 286 | 48 | 0.0858676207513416 | 2 |
PARD3-208 | PARD3 | Q8TEW0 | Partitioning defective 3 homolog | chr10 | GO:0007409 | Not Cancer Driver | No | 148 | 0.1091445427728613 | 1147 | 128 | 0.0943952802359882 | 2 |
PARD6B-201 | PARD6B | Q9BYG5 | Partitioning defective 6 homolog beta | chr20 | GO:0007409 | Not Cancer Driver | No | 41 | 0.1102150537634408 | 166 | 18 | 0.0483870967741935 | 0 |
PAX2-205 | PAX2 | Q02962 | Paired box protein Pax-2 | chr10 | GO:0007409 | Not Cancer Driver | No | 49 | 0.1175059952038369 | 294 | 39 | 0.0935251798561151 | 22 |
PICALM-202 | PICALM | Q13492 | Phosphatidylinositol-binding clathrin assembly protein | chr11 | GO:0007409 | Census | Yes | 64 | 0.0981595092024539 | 320 | 31 | 0.0475460122699386 | 0 |
PITPNA-201 | PITPNA | Q00169 | Phosphatidylinositol transfer protein alpha isoform | chr17 | GO:0007409 | Not Cancer Driver | No | 17 | 0.0629629629629629 | 82 | 6 | 0.0222222222222222 | 0 |
PLPPR4-202 | PLPPR4 | Q7Z2D5 | Phospholipid phosphatase-related protein type 4 | chr1 | GO:0007409 | Not Cancer Driver | No | 156 | 0.2181818181818181 | 419 | 103 | 0.144055944055944 | 0 |
POTEE-205 | POTEE | Q6S8J3 | POTE ankyrin domain family member E | chr2 | GO:0007409 | Not Cancer Driver | No | 228 | 0.2120930232558139 | 465 | 75 | 0.0697674418604651 | 0 |
POTEF-202 | POTEF | A5A3E0 | POTE ankyrin domain family member F | chr2 | GO:0007409 | Not Cancer Driver | No | 174 | 0.161860465116279 | 456 | 63 | 0.0586046511627907 | 0 |
POTEI-201 | POTEI | P0CG38 | POTE ankyrin domain family member I | chr2 | GO:0007409 | Not Cancer Driver | No | 0 | 0.0 | 452 | 0 | 0.0 | 0 |
POTEJ-201 | POTEJ | P0CG39 | POTE ankyrin domain family member J | chr2 | GO:0007409 | Not Cancer Driver | No | 0 | 0.0 | 426 | 0 | 0.0 | 0 |
POU4F1-201 | POU4F1 | Q01851 | POU domain, class 4, transcription factor 1 | chr13 | GO:0007409 | Not Cancer Driver | No | 33 | 0.0787589498806682 | 274 | 20 | 0.0477326968973747 | 1 |
PRICKLE1-201 | PRICKLE1 | Q96MT3 | Prickle-like protein 1 | chr12 | GO:0007409 | Not Cancer Driver | No | 118 | 0.1419975932611311 | 485 | 71 | 0.0854392298435619 | 3 |
PTPN11-201 | PTPN11 | Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | chr12 | GO:0007409 | Census, Compendium | Yes | 92 | 0.1551433389544688 | 260 | 27 | 0.0455311973018549 | 44 |
PTPRZ1-201 | PTPRZ1 | P23471 | Receptor-type tyrosine-protein phosphatase zeta | chr7 | GO:0007409 | Not Cancer Driver | No | 321 | 0.1386609071274298 | 980 | 142 | 0.0613390928725701 | 0 |
RAB10-201 | RAB10 | P61026 | Ras-related protein Rab-10 | chr2 | GO:0007409 | Not Cancer Driver | No | 12 | 0.06 | 28 | 1 | 0.005 | 0 |
RAB3A-201 | RAB3A | P20336 | Ras-related protein Rab-3A | chr19 | GO:0007409 | Not Cancer Driver | No | 19 | 0.0863636363636363 | 43 | 3 | 0.0136363636363636 | 0 |
RAB8A-201 | RAB8A | P61006 | Ras-related protein Rab-8A | chr19 | GO:0007409 | Not Cancer Driver | No | 30 | 0.144927536231884 | 26 | 3 | 0.0144927536231884 | 0 |
RTN4R-201 | RTN4R | Q9BZR6 | Reticulon-4 receptor | chr22 | GO:0007409 | Not Cancer Driver | No | 34 | 0.0718816067653276 | 148 | 17 | 0.0359408033826638 | 4 |
RYK-208 | RYK | P34925 | Tyrosine-protein kinase RYK | chr3 | GO:0007409 | Not Cancer Driver | No | 38 | 0.0626029654036243 | 85 | 3 | 0.0049423393739703 | 0 |
S100A6-201 | S100A6 | P06703 | Protein S100-A6 | chr1 | GO:0007409 | Not Cancer Driver | No | 5 | 0.0555555555555555 | 4 | 0 | 0.0 | 0 |
S100B-201 | S100B | P04271 | Protein S100-B | chr21 | GO:0007409 | Not Cancer Driver | No | 8 | 0.0869565217391304 | 14 | 0 | 0.0 | 0 |
SCN11A-201 | SCN11A | Q9UI33 | Sodium channel protein type 11 subunit alpha | chr3 | GO:0007409 | Not Cancer Driver | No | 373 | 0.2082635399218314 | 200 | 45 | 0.0251256281407035 | 8 |
SHTN1-202 | SHTN1 | A0MZ66 | Shootin-1 | chr10 | GO:0007409 | Census | Yes | 52 | 0.0824088748019017 | 471 | 42 | 0.0665610142630744 | 0 |
SLITRK1-202 | SLITRK1 | Q96PX8 | SLIT and NTRK-like protein 1 | chr13 | GO:0007409 | Not Cancer Driver | No | 242 | 0.3477011494252873 | 126 | 50 | 0.0718390804597701 | 2 |
SLITRK2-201 | SLITRK2 | Q9H156 | SLIT and NTRK-like protein 2 | chrX | GO:0007409 | Not Cancer Driver | No | 226 | 0.2674556213017751 | 245 | 67 | 0.0792899408284023 | 0 |
SLITRK3-202 | SLITRK3 | O94933 | SLIT and NTRK-like protein 3 | chr3 | GO:0007409 | Not Cancer Driver | No | 256 | 0.2620266120777891 | 322 | 103 | 0.1054247697031729 | 0 |
SLITRK4-202 | SLITRK4 | Q8IW52 | SLIT and NTRK-like protein 4 | chrX | GO:0007409 | Not Cancer Driver | No | 201 | 0.2401433691756272 | 172 | 35 | 0.041816009557945 | 0 |
SLITRK5-202 | SLITRK5 | O94991 | SLIT and NTRK-like protein 5 | chr13 | GO:0007409 | Not Cancer Driver | No | 203 | 0.2118997912317327 | 346 | 77 | 0.080375782881002 | 0 |
SLITRK6-203 | SLITRK6 | Q9H5Y7 | SLIT and NTRK-like protein 6 | chr13 | GO:0007409 | Not Cancer Driver | No | 184 | 0.2187871581450653 | 226 | 44 | 0.0523186682520808 | 0 |
SNAP25-201 | SNAP25 | P60880 | Synaptosomal-associated protein 25 | chr20 | GO:0007409 | Not Cancer Driver | No | 46 | 0.2233009708737864 | 178 | 38 | 0.1844660194174757 | 1 |
SPAST-201 | SPAST | Q9UBP0 | Spastin | chr2 | GO:0007409 | Not Cancer Driver | No | 52 | 0.0844155844155844 | 270 | 16 | 0.0259740259740259 | 62 |
SPTBN4-210 | SPTBN4 | Q9H254 | Spectrin beta chain, non-erythrocytic 4 | chr19 | GO:0007409 | Not Cancer Driver | No | 264 | 0.1029641185647426 | 871 | 75 | 0.0292511700468018 | 0 |
SSNA1-201 | SSNA1 | O43805 | Microtubule nucleation factor SSNA1 | chr9 | GO:0007409 | Not Cancer Driver | No | 9 | 0.0756302521008403 | 74 | 8 | 0.0672268907563025 | 0 |
STK11-201 | STK11 | Q15831 | Serine/threonine-protein kinase STK11 | chr19 | GO:0007409 | Census, Compendium | Yes | 63 | 0.1454965357967667 | 135 | 12 | 0.0277136258660508 | 9 |
STK25-201 | STK25 | O00506 | Serine/threonine-protein kinase 25 | chr2 | GO:0007409 | Not Cancer Driver | No | 34 | 0.0798122065727699 | 171 | 13 | 0.0305164319248826 | 0 |
STMN1-206 | STMN1 | P16949 | Stathmin | chr1 | GO:0007409 | Not Cancer Driver | No | 8 | 0.0536912751677852 | 149 | 8 | 0.0536912751677852 | 0 |
SYNGAP1-229 | SYNGAP1 | Q96PV0 | Ras/Rap GTPase-activating protein SynGAP | chr6 | GO:0007409 | Not Cancer Driver | No | 113 | 0.0841399851079672 | 833 | 66 | 0.0491437081161578 | 4 |
TAOK2-202 | TAOK2 | Q9UL54 | Serine/threonine-protein kinase TAO2 | chr16 | GO:0007409 | Not Cancer Driver | No | 129 | 0.1044534412955465 | 668 | 68 | 0.0550607287449392 | 0 |
TNN-201 | TNN | Q9UQP3 | Tenascin-N | chr1 | GO:0007409 | Not Cancer Driver | No | 357 | 0.2748267898383372 | 642 | 199 | 0.153194765204003 | 0 |
TOP2B-201 | TOP2B | Q02880 | DNA topoisomerase 2-beta | chr3 | GO:0007409 | Not Cancer Driver | No | 82 | 0.050430504305043 | 545 | 27 | 0.0166051660516605 | 4 |
TRIM46-201 | TRIM46 | Q7Z4K8 | Tripartite motif-containing protein 46 | chr1 | GO:0007409 | Not Cancer Driver | No | 85 | 0.1119894598155467 | 174 | 25 | 0.0329380764163372 | 0 |
VAX2-201 | VAX2 | Q9UIW0 | Ventral anterior homeobox 2 | chr2 | GO:0007409 | Not Cancer Driver | No | 27 | 0.093103448275862 | 211 | 16 | 0.0551724137931034 | 0 |
WNT7A-201 | WNT7A | O00755 | Protein Wnt-7a | chr3 | GO:0007409 | Not Cancer Driver | No | 68 | 0.1948424068767908 | 18 | 6 | 0.0171919770773638 | 4 |
ZDHHC17-201 | ZDHHC17 | Q8IUH5 | Palmitoyltransferase ZDHHC17 | chr12 | GO:0007409 | Not Cancer Driver | No | 61 | 0.0965189873417721 | 50 | 6 | 0.0094936708860759 | 0 |