Total number of protein in "GO:0008013" GO term: 87
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ADNP-205 | ADNP | Q9H2P0 | Activity-dependent neuroprotector homeobox protein | chr20 | GO:0008013 | Not Cancer Driver | No | 96 | 0.087114337568058 | 615 | 52 | 0.0471869328493647 | 0 |
AJAP1-202 | AJAP1 | Q9UKB5 | Adherens junction-associated protein 1 | chr1 | GO:0008013 | Not Cancer Driver | No | 83 | 0.2019464720194647 | 274 | 54 | 0.1313868613138686 | 0 |
AMER1-201 | AMER1 | Q5JTC6 | APC membrane recruitment protein 1 | chrX | GO:0008013 | Census, Compendium | Yes | 196 | 0.1726872246696035 | 1041 | 185 | 0.1629955947136563 | 0 |
AMER2-202 | AMER2 | Q8N7J2 | APC membrane recruitment protein 2 | chr13 | GO:0008013 | Not Cancer Driver | No | 90 | 0.1341281669150521 | 663 | 88 | 0.1311475409836065 | 0 |
AMER3-201 | AMER3 | Q8N944 | APC membrane recruitment protein 3 | chr2 | GO:0008013 | Not Cancer Driver | No | 198 | 0.229965156794425 | 737 | 173 | 0.2009291521486643 | 0 |
APC-201 | APC | P25054 | Adenomatous polyposis coli protein | chr5 | GO:0008013 | Census, Compendium | Yes | 295 | 0.1037636299683433 | 2412 | 248 | 0.0872317973971157 | 22 |
APC2-206 | APC2 | O95996 | Adenomatous polyposis coli protein 2 | chr19 | GO:0008013 | Not Cancer Driver | No | 86 | 0.0373425966131133 | 1739 | 61 | 0.0264871906209292 | 0 |
AR-201 | AR | P10275 | Androgen receptor | chrX | GO:0008013 | Census, Compendium | Yes | 116 | 0.1260869565217391 | 443 | 38 | 0.0413043478260869 | 144 |
ASH2L-201 | ASH2L | Q9UBL3 | Set1/Ash2 histone methyltransferase complex subunit ASH2 | chr8 | GO:0008013 | Not Cancer Driver | No | 71 | 0.1130573248407643 | 294 | 33 | 0.0525477707006369 | 0 |
AXIN1-201 | AXIN1 | O15169 | Axin-1 | chr16 | GO:0008013 | Census, Compendium | Yes | 91 | 0.105568445475638 | 623 | 69 | 0.0800464037122969 | 4 |
AXIN2-201 | AXIN2 | Q9Y2T1 | Axin-2 | chr17 | GO:0008013 | Census, Compendium | Yes | 82 | 0.0972716488730723 | 551 | 51 | 0.0604982206405693 | 0 |
BCL9-201 | BCL9 | O00512 | B-cell CLL/lymphoma 9 protein | chr1 | GO:0008013 | Census, Compendium | Yes | 164 | 0.1150070126227209 | 1431 | 164 | 0.1150070126227209 | 0 |
BCL9L-205 | BCL9L | Q86UU0 | B-cell CLL/lymphoma 9-like protein | chr11 | GO:0008013 | Census, Compendium | Yes | 166 | 0.1107404936624416 | 1501 | 166 | 0.1107404936624416 | 0 |
BTRC-202 | BTRC | Q9Y297 | F-box/WD repeat-containing protein 1A | chr10 | GO:0008013 | Not Cancer Driver | No | 57 | 0.0942148760330578 | 45 | 3 | 0.0049586776859504 | 0 |
CALCOCO1-218 | CALCOCO1 | Q9P1Z2 | Calcium-binding and coiled-coil domain-containing protein 1 | chr12 | GO:0008013 | Not Cancer Driver | No | 74 | 0.1070911722141823 | 489 | 48 | 0.0694645441389291 | 0 |
CARM1-201 | CARM1 | Q86X55 | Histone-arginine methyltransferase CARM1 | chr19 | GO:0008013 | Not Cancer Driver | No | 47 | 0.0773026315789473 | 102 | 7 | 0.0115131578947368 | 0 |
CBY1-201 | CBY1 | Q9Y3M2 | Protein chibby homolog 1 | chr22 | GO:0008013 | Not Cancer Driver | No | 9 | 0.0714285714285714 | 98 | 7 | 0.0555555555555555 | 0 |
CDH1-201 | CDH1 | P12830 | Cadherin-1 | chr16 | GO:0008013 | Census, Compendium | Yes | 125 | 0.1417233560090703 | 401 | 70 | 0.0793650793650793 | 5 |
CDH2-201 | CDH2 | P19022 | Cadherin-2 | chr18 | GO:0008013 | Not Cancer Driver | No | 182 | 0.2008830022075055 | 464 | 107 | 0.1181015452538631 | 7 |
CDH26-202 | CDH26 | Q8IXH8 | Cadherin-like protein 26 | chr20 | GO:0008013 | Not Cancer Driver | No | 124 | 0.1490384615384615 | 299 | 45 | 0.0540865384615384 | 0 |
CDH5-201 | CDH5 | P33151 | Cadherin-5 | chr16 | GO:0008013 | Not Cancer Driver | No | 121 | 0.1543367346938775 | 305 | 44 | 0.0561224489795918 | 0 |
CDHR5-203 | CDHR5 | Q9HBB8 | Cadherin-related family member 5 | chr11 | GO:0008013 | Not Cancer Driver | No | 78 | 0.0923076923076923 | 511 | 41 | 0.0485207100591716 | 0 |
CHD8-224 | CHD8 | Q9HCK8 | Chromodomain-helicase-DNA-binding protein 8 | chr14 | GO:0008013 | Not Cancer Driver | No | 234 | 0.0906625339015885 | 1413 | 107 | 0.0414567996900426 | 0 |
CTNNA1-201 | CTNNA1 | P35221 | Catenin alpha-1 | chr5 | GO:0008013 | Census | Yes | 90 | 0.0993377483443708 | 268 | 25 | 0.0275938189845474 | 4 |
CTNNA2-203 | CTNNA2 | P26232 | Catenin alpha-2 | chr2 | GO:0008013 | Census | Yes | 328 | 0.3441762854144806 | 308 | 108 | 0.1133263378803777 | 0 |
CTNNA3-203 | CTNNA3 | Q9UI47 | Catenin alpha-3 | chr10 | GO:0008013 | Not Cancer Driver | No | 225 | 0.2513966480446927 | 187 | 37 | 0.041340782122905 | 1 |
CTNNBIP1-203 | CTNNBIP1 | Q9NSA3 | Beta-catenin-interacting protein 1 | chr1 | GO:0008013 | Not Cancer Driver | No | 8 | 0.0987654320987654 | 64 | 7 | 0.0864197530864197 | 0 |
CTNND1-205 | CTNND1 | O60716 | Catenin delta-1 | chr11 | GO:0008013 | Census | Yes | 108 | 0.1115702479338843 | 571 | 63 | 0.0650826446280991 | 0 |
CTNND2-201 | CTNND2 | Q9UQB3 | Catenin delta-2 | chr5 | GO:0008013 | Census | Yes | 338 | 0.2759183673469387 | 841 | 228 | 0.1861224489795918 | 6 |
CXADR-201 | CXADR | P78310 | Coxsackievirus and adenovirus receptor | chr21 | GO:0008013 | Not Cancer Driver | No | 40 | 0.1095890410958904 | 99 | 15 | 0.0410958904109589 | 0 |
DACT1-201 | DACT1 | Q9NYF0 | Dapper homolog 1 | chr14 | GO:0008013 | Not Cancer Driver | No | 131 | 0.1566985645933014 | 604 | 104 | 0.124401913875598 | 1 |
DACT2-201 | DACT2 | Q5SW24 | Dapper homolog 2 | chr6 | GO:0008013 | Not Cancer Driver | No | 23 | 0.0297157622739018 | 662 | 19 | 0.024547803617571 | 0 |
DLG5-201 | DLG5 | Q8TDM6 | Disks large homolog 5 | chr10 | GO:0008013 | Not Cancer Driver | No | 184 | 0.09588327253778 | 1119 | 107 | 0.0557582073996873 | 0 |
DVL1-201 | DVL1 | O14640 | Segment polarity protein dishevelled homolog DVL-1 | chr1 | GO:0008013 | Not Cancer Driver | No | 42 | 0.0604316546762589 | 434 | 16 | 0.0230215827338129 | 0 |
DVL3-201 | DVL3 | Q92997 | Segment polarity protein dishevelled homolog DVL-3 | chr3 | GO:0008013 | Not Cancer Driver | No | 58 | 0.0810055865921787 | 437 | 31 | 0.0432960893854748 | 0 |
EP300-201 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | GO:0008013 | Census, Compendium | Yes | 203 | 0.084092792046396 | 1792 | 84 | 0.0347970173985087 | 1 |
ESR1-201 | ESR1 | P03372 | Estrogen receptor | chr6 | GO:0008013 | Census, Compendium | Yes | 92 | 0.1546218487394958 | 198 | 19 | 0.0319327731092436 | 2 |
FOXO1-201 | FOXO1 | Q12778 | Forkhead box protein O1 | chr13 | GO:0008013 | Census, Compendium | Yes | 52 | 0.0793893129770992 | 586 | 51 | 0.0778625954198473 | 0 |
FOXO3-202 | FOXO3 | O43524 | Forkhead box protein O3 | chr6 | GO:0008013 | Census, Compendium | Yes | 54 | 0.0802377414561664 | 597 | 50 | 0.0742942050520059 | 0 |
FOXO4-202 | FOXO4 | P98177 | Forkhead box protein O4 | chrX | GO:0008013 | Census | Yes | 56 | 0.1108910891089108 | 441 | 45 | 0.0891089108910891 | 0 |
GJA1-201 | GJA1 | P17302 | Gap junction alpha-1 protein | chr6 | GO:0008013 | Not Cancer Driver | No | 62 | 0.1623036649214659 | 111 | 20 | 0.0523560209424083 | 43 |
GLI3-201 | GLI3 | P10071 | Transcriptional activator GLI3 | chr7 | GO:0008013 | Not Cancer Driver | No | 308 | 0.1949367088607595 | 1362 | 270 | 0.170886075949367 | 7 |
GRIP1-201 | GRIP1 | Q9Y3R0 | Glutamate receptor-interacting protein 1 | chr12 | GO:0008013 | Not Cancer Driver | No | 162 | 0.1436170212765957 | 569 | 84 | 0.0744680851063829 | 0 |
GSK3B-201 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | GO:0008013 | Not Cancer Driver | No | 34 | 0.0809523809523809 | 148 | 6 | 0.0142857142857142 | 0 |
GSKIP-205 | GSKIP | Q9P0R6 | GSK3B-interacting protein | chr14 | GO:0008013 | Not Cancer Driver | No | 9 | 0.0647482014388489 | 32 | 1 | 0.0071942446043165 | 0 |
HDAC6-201 | HDAC6 | Q9UBN7 | Histone deacetylase 6 | chrX | GO:0008013 | Not Cancer Driver | No | 122 | 0.1004115226337448 | 409 | 35 | 0.0288065843621399 | 0 |
KANK1-205 | KANK1 | Q14678 | KN motif and ankyrin repeat domain-containing protein 1 | chr9 | GO:0008013 | Not Cancer Driver | No | 123 | 0.0909763313609467 | 803 | 74 | 0.0547337278106508 | 0 |
KDM6B-202 | KDM6B | O15054 | Lysine-specific demethylase 6B | chr17 | GO:0008013 | Not Cancer Driver | No | 151 | 0.0919050517346317 | 1288 | 116 | 0.0706025562994522 | 2 |
KLF4-201 | KLF4 | O43474 | Krueppel-like factor 4 | chr9 | GO:0008013 | Census, Compendium | Yes | 41 | 0.0855949895615866 | 417 | 25 | 0.0521920668058455 | 0 |
LEF1-201 | LEF1 | Q9UJU2 | Lymphoid enhancer-binding factor 1 | chr4 | GO:0008013 | Census | Yes | 51 | 0.1278195488721804 | 372 | 47 | 0.1177944862155388 | 0 |
LZIC-202 | LZIC | Q8WZA0 | Protein LZIC | chr1 | GO:0008013 | Not Cancer Driver | No | 13 | 0.0684210526315789 | 66 | 5 | 0.0263157894736842 | 0 |
MED12-202 | MED12 | Q93074 | Mediator of RNA polymerase II transcription subunit 12 | chrX | GO:0008013 | Census, Compendium | Yes | 300 | 0.1378043178686265 | 975 | 129 | 0.0592558566835094 | 5 |
MED12L-206 | MED12L | Q86YW9 | Mediator of RNA polymerase II transcription subunit 12-like protein | chr3 | GO:0008013 | Not Cancer Driver | No | 287 | 0.1337995337995338 | 825 | 123 | 0.0573426573426573 | 0 |
NHERF1-201 | NHERF1 | O14745 | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | chr17 | GO:0008013 | Not Cancer Driver | No | 15 | 0.0418994413407821 | 319 | 12 | 0.0335195530726257 | 4 |
NHERF2-201 | NHERF2 | Q15599 | Na(+)/H(+) exchange regulatory cofactor NHE-RF2 | chr16 | GO:0008013 | Not Cancer Driver | No | 21 | 0.0623145400593471 | 331 | 21 | 0.0623145400593471 | 0 |
NR4A2-201 | NR4A2 | P43354 | Nuclear receptor subfamily 4 group A member 2 | chr2 | GO:0008013 | Not Cancer Driver | No | 84 | 0.1404682274247491 | 262 | 32 | 0.0535117056856187 | 3 |
NUMB-213 | NUMB | P49757 | Protein numb homolog | chr14 | GO:0008013 | Not Cancer Driver | No | 50 | 0.0768049155145929 | 489 | 42 | 0.064516129032258 | 0 |
PIN1-201 | PIN1 | Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | chr19 | GO:0008013 | Not Cancer Driver | No | 13 | 0.0797546012269938 | 116 | 11 | 0.0674846625766871 | 0 |
PRKN-206 | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:0008013 | Not Cancer Driver | No | 96 | 0.2064516129032258 | 78 | 14 | 0.0301075268817204 | 30 |
PROP1-201 | PROP1 | O75360 | Homeobox protein prophet of Pit-1 | chr5 | GO:0008013 | Not Cancer Driver | No | 28 | 0.1238938053097345 | 195 | 27 | 0.1194690265486725 | 6 |
PSEN1-201 | PSEN1 | P49768 | Presenilin-1 | chr14 | GO:0008013 | Not Cancer Driver | No | 43 | 0.0920770877944325 | 134 | 18 | 0.038543897216274 | 69 |
PTPRJ-201 | PTPRJ | Q12913 | Receptor-type tyrosine-protein phosphatase eta | chr11 | GO:0008013 | Not Cancer Driver | No | 130 | 0.0972326103216155 | 403 | 39 | 0.0291697830964846 | 0 |
PTPRK-206 | PTPRK | Q15262 | Receptor-type tyrosine-protein phosphatase kappa | chr6 | GO:0008013 | Census, Compendium | Yes | 233 | 0.1619179986101459 | 302 | 44 | 0.0305767894371091 | 0 |
PTPRT-203 | PTPRT | O14522 | Receptor-type tyrosine-protein phosphatase T | chr20 | GO:0008013 | Census, Compendium | Yes | 460 | 0.3192227619708536 | 298 | 104 | 0.0721721027064538 | 0 |
PTPRU-201 | PTPRU | Q92729 | Receptor-type tyrosine-protein phosphatase U | chr1 | GO:0008013 | Not Cancer Driver | No | 186 | 0.1286307053941908 | 325 | 48 | 0.0331950207468879 | 0 |
PXN-201 | PXN | P49023 | Paxillin | chr12 | GO:0008013 | Not Cancer Driver | No | 41 | 0.0693739424703891 | 342 | 14 | 0.0236886632825719 | 0 |
RNF220-203 | RNF220 | Q5VTB9 | E3 ubiquitin-protein ligase RNF220 | chr1 | GO:0008013 | Not Cancer Driver | No | 72 | 0.127208480565371 | 402 | 48 | 0.0848056537102473 | 2 |
RORA-203 | RORA | P35398 | Nuclear receptor ROR-alpha | chr15 | GO:0008013 | Not Cancer Driver | No | 43 | 0.0822179732313575 | 181 | 11 | 0.0210325047801147 | 4 |
RUVBL2-206 | RUVBL2 | Q9Y230 | RuvB-like 2 | chr19 | GO:0008013 | Not Cancer Driver | No | 52 | 0.1123110151187904 | 100 | 11 | 0.0237580993520518 | 0 |
SALL1-201 | SALL1 | Q9NSC2 | Sal-like protein 1 | chr16 | GO:0008013 | Not Cancer Driver | No | 372 | 0.2809667673716012 | 952 | 270 | 0.2039274924471299 | 0 |
SETD1A-201 | SETD1A | O15047 | Histone-lysine N-methyltransferase SETD1A | chr16 | GO:0008013 | Not Cancer Driver | No | 111 | 0.0650263620386643 | 1329 | 99 | 0.0579964850615114 | 5 |
SHROOM2-201 | SHROOM2 | Q13796 | Protein Shroom2 | chrX | GO:0008013 | Not Cancer Driver | No | 182 | 0.1126237623762376 | 1387 | 158 | 0.0977722772277227 | 0 |
SKP1-202 | SKP1 | P63208 | S-phase kinase-associated protein 1 | chr5 | GO:0008013 | Not Cancer Driver | No | 20 | 0.1226993865030674 | 96 | 19 | 0.1165644171779141 | 0 |
SMAD3-201 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0008013 | Census, Compendium | Yes | 80 | 0.188235294117647 | 113 | 15 | 0.0352941176470588 | 5 |
SMAD7-201 | SMAD7 | O15105 | Mothers against decapentaplegic homolog 7 | chr18 | GO:0008013 | Not Cancer Driver | No | 38 | 0.0892018779342723 | 140 | 0 | 0.0 | 0 |
SOX17-201 | SOX17 | Q9H6I2 | Transcription factor SOX-17 | chr8 | GO:0008013 | Compendium | Yes | 64 | 0.1545893719806763 | 379 | 45 | 0.108695652173913 | 2 |
SOX30-201 | SOX30 | O94993 | Transcription factor SOX-30 | chr5 | GO:0008013 | Not Cancer Driver | No | 79 | 0.1049136786188579 | 664 | 70 | 0.0929614873837981 | 0 |
SOX9-201 | SOX9 | P48436 | Transcription factor SOX-9 | chr17 | GO:0008013 | Compendium | Yes | 69 | 0.1355599214145383 | 497 | 66 | 0.1296660117878192 | 13 |
SUFU-202 | SUFU | Q9UMX1 | Suppressor of fused homolog | chr10 | GO:0008013 | Census | Yes | 48 | 0.0991735537190082 | 200 | 15 | 0.03099173553719 | 2 |
TAX1BP3-201 | TAX1BP3 | O14907 | Tax1-binding protein 3 | chr17 | GO:0008013 | Not Cancer Driver | No | 12 | 0.0967741935483871 | 52 | 5 | 0.0403225806451612 | 0 |
TBL1XR1-214 | TBL1XR1 | Q9BZK7 | F-box-like/WD repeat-containing protein TBL1XR1 | chr3 | GO:0008013 | Census, Compendium | Yes | 68 | 0.1322957198443579 | 136 | 14 | 0.0272373540856031 | 4 |
TCF4-202 | TCF4 | P15884 | Transcription factor 4 | chr18 | GO:0008013 | Compendium | Yes | 105 | 0.1574212893553223 | 662 | 104 | 0.1559220389805097 | 10 |
TCF7-201 | TCF7 | P36402 | Transcription factor 7 | chr5 | GO:0008013 | Not Cancer Driver | No | 26 | 0.0677083333333333 | 307 | 23 | 0.0598958333333333 | 0 |
TCF7L2-206 | TCF7L2 | Q9NQB0 | Transcription factor 7-like 2 | chr10 | GO:0008013 | Census, Compendium | Yes | 76 | 0.122778675282714 | 517 | 62 | 0.1001615508885298 | 0 |
TREM2-202 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:0008013 | Not Cancer Driver | No | 31 | 0.1347826086956521 | 27 | 2 | 0.008695652173913 | 1 |
TRPC4-206 | TRPC4 | Q9UBN4 | Short transient receptor potential channel 4 | chr13 | GO:0008013 | Not Cancer Driver | No | 226 | 0.2313203684749232 | 196 | 42 | 0.0429887410440122 | 0 |
VCL-201 | VCL | P18206 | Vinculin | chr10 | GO:0008013 | Not Cancer Driver | No | 83 | 0.0731922398589065 | 680 | 60 | 0.0529100529100529 | 2 |