Total number of protein in "GO:0008217" GO term: 72
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACE-202 | ACE | P12821 | Angiotensin-converting enzyme | chr17 | GO:0008217 | Not Cancer Driver | No | 152 | 0.116385911179173 | 87 | 5 | 0.0038284839203675 | 0 |
| ACSM3-201 | ACSM3 | Q53FZ2 | Acyl-coenzyme A synthetase ACSM3, mitochondrial | chr16 | GO:0008217 | Not Cancer Driver | No | 59 | 0.1006825938566552 | 80 | 4 | 0.0068259385665529 | 0 |
| ACTA2-201 | ACTA2 | P62736 | Actin, aortic smooth muscle | chr10 | GO:0008217 | Not Cancer Driver | No | 42 | 0.1114058355437665 | 39 | 3 | 0.0079575596816976 | 15 |
| ACVRL1-201 | ACVRL1 | P37023 | Serine/threonine-protein kinase receptor R3 | chr12 | GO:0008217 | Not Cancer Driver | No | 80 | 0.1590457256461232 | 60 | 10 | 0.0198807157057654 | 64 |
| AGT-201 | AGT | P01019 | Angiotensinogen | chr1 | GO:0008217 | Not Cancer Driver | No | 61 | 0.1281512605042016 | 33 | 3 | 0.0063025210084033 | 1 |
| AGTR2-201 | AGTR2 | P50052 | Type-2 angiotensin II receptor | chrX | GO:0008217 | Not Cancer Driver | No | 67 | 0.1845730027548209 | 0 | 0 | 0.0 | 0 |
| AGTRAP-201 | AGTRAP | Q6RW13 | Type-1 angiotensin II receptor-associated protein | chr1 | GO:0008217 | Not Cancer Driver | No | 15 | 0.0943396226415094 | 11 | 0 | 0.0 | 0 |
| ATP1A1-201 | ATP1A1 | P05023 | Sodium/potassium-transporting ATPase subunit alpha-1 | chr1 | GO:0008217 | Census | Yes | 76 | 0.0742913000977517 | 115 | 14 | 0.0136852394916911 | 6 |
| ATP1A2-201 | ATP1A2 | P50993 | Sodium/potassium-transporting ATPase subunit alpha-2 | chr1 | GO:0008217 | Not Cancer Driver | No | 162 | 0.1588235294117647 | 162 | 21 | 0.0205882352941176 | 14 |
| ATP2B1-202 | ATP2B1 | P20020 | Plasma membrane calcium-transporting ATPase 1 | chr12 | GO:0008217 | Not Cancer Driver | No | 103 | 0.0844262295081967 | 294 | 30 | 0.0245901639344262 | 9 |
| BRS3-201 | BRS3 | P32247 | Bombesin receptor subtype-3 | chrX | GO:0008217 | Not Cancer Driver | No | 52 | 0.1303258145363408 | 32 | 9 | 0.0225563909774436 | 0 |
| CHGA-201 | CHGA | P10645 | Chromogranin-A | chr14 | GO:0008217 | Not Cancer Driver | No | 36 | 0.0787746170678337 | 421 | 35 | 0.0765864332603938 | 0 |
| COL1A2-201 | COL1A2 | P08123 | Collagen alpha-2(I) chain | chr7 | GO:0008217 | Not Cancer Driver | No | 84 | 0.0614934114202049 | 1160 | 50 | 0.0366032210834553 | 81 |
| CORIN-201 | CORIN | Q9Y5Q5 | Atrial natriuretic peptide-converting enzyme | chr4 | GO:0008217 | Not Cancer Driver | No | 153 | 0.1468330134357005 | 60 | 11 | 0.010556621880998 | 2 |
| CYP11B1-201 | CYP11B1 | P15538 | Cytochrome P450 11B1, mitochondrial | chr8 | GO:0008217 | Not Cancer Driver | No | 154 | 0.3061630218687873 | 7 | 0 | 0.0 | 44 |
| CYP4F2-202 | CYP4F2 | P78329 | Cytochrome P450 4F2 | chr19 | GO:0008217 | Not Cancer Driver | No | 110 | 0.2115384615384615 | 17 | 2 | 0.0038461538461538 | 0 |
| DLL1-201 | DLL1 | O00548 | Delta-like protein 1 | chr6 | GO:0008217 | Not Cancer Driver | No | 81 | 0.1120331950207468 | 145 | 15 | 0.0207468879668049 | 1 |
| EDNRA-209 | EDNRA | P25101 | Endothelin-1 receptor | chr4 | GO:0008217 | Not Cancer Driver | No | 52 | 0.1217798594847775 | 21 | 5 | 0.0117096018735363 | 2 |
| EMILIN1-201 | EMILIN1 | Q9Y6C2 | EMILIN-1 | chr2 | GO:0008217 | Not Cancer Driver | No | 89 | 0.0875984251968503 | 671 | 50 | 0.0492125984251968 | 1 |
| EMILIN2-201 | EMILIN2 | Q9BXX0 | EMILIN-2 | chr18 | GO:0008217 | Not Cancer Driver | No | 128 | 0.1215574548907882 | 620 | 75 | 0.0712250712250712 | 0 |
| ENPEP-201 | ENPEP | Q07075 | Glutamyl aminopeptidase | chr4 | GO:0008217 | Compendium | Yes | 157 | 0.1640543364681295 | 130 | 29 | 0.0303030303030303 | 0 |
| ERAP1-202 | ERAP1 | Q9NZ08 | Endoplasmic reticulum aminopeptidase 1 | chr5 | GO:0008217 | Not Cancer Driver | No | 57 | 0.0605738575982996 | 70 | 1 | 0.0010626992561105 | 0 |
| ERAP2-202 | ERAP2 | Q6P179 | Endoplasmic reticulum aminopeptidase 2 | chr5 | GO:0008217 | Not Cancer Driver | No | 73 | 0.0760416666666666 | 23 | 4 | 0.0041666666666666 | 0 |
| EXT1-201 | EXT1 | Q16394 | Exostosin-1 | chr8 | GO:0008217 | Census | Yes | 75 | 0.1005361930294906 | 60 | 7 | 0.0093833780160857 | 8 |
| EXT2-208 | EXT2 | Q93063 | Exostosin-2 | chr11 | GO:0008217 | Census, Compendium | Yes | 69 | 0.096100278551532 | 12 | 1 | 0.0013927576601671 | 9 |
| GCGR-201 | GCGR | P47871 | Glucagon receptor | chr17 | GO:0008217 | Not Cancer Driver | No | 12 | 0.0251572327044025 | 56 | 2 | 0.0041928721174004 | 4 |
| GCH1-204 | GCH1 | P30793 | GTP cyclohydrolase 1 | chr14 | GO:0008217 | Not Cancer Driver | No | 14 | 0.056 | 102 | 3 | 0.012 | 35 |
| GNA11-201 | GNA11 | P29992 | Guanine nucleotide-binding protein subunit alpha-11 | chr19 | GO:0008217 | Census, Compendium | Yes | 74 | 0.2061281337047353 | 10 | 0 | 0.0 | 5 |
| GNA12-201 | GNA12 | Q03113 | Guanine nucleotide-binding protein subunit alpha-12 | chr7 | GO:0008217 | Not Cancer Driver | No | 30 | 0.0787401574803149 | 20 | 0 | 0.0 | 0 |
| GNA13-201 | GNA13 | Q14344 | Guanine nucleotide-binding protein subunit alpha-13 | chr17 | GO:0008217 | Compendium | Yes | 45 | 0.1193633952254641 | 32 | 4 | 0.0106100795755968 | 0 |
| GNB3-201 | GNB3 | P16520 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 | chr12 | GO:0008217 | Not Cancer Driver | No | 43 | 0.1264705882352941 | 13 | 1 | 0.0029411764705882 | 0 |
| GUCY1A1-205 | GUCY1A1 | Q02108 | Guanylate cyclase soluble subunit alpha-1 | chr4 | GO:0008217 | Not Cancer Driver | No | 147 | 0.2130434782608695 | 54 | 8 | 0.0115942028985507 | 0 |
| HBB-201 | HBB | P68871 | Hemoglobin subunit beta | chr11 | GO:0008217 | Not Cancer Driver | No | 32 | 0.2176870748299319 | 7 | 1 | 0.0068027210884353 | 5 |
| KCNJ8-201 | KCNJ8 | Q15842 | ATP-sensitive inward rectifier potassium channel 8 | chr12 | GO:0008217 | Not Cancer Driver | No | 78 | 0.1839622641509433 | 69 | 17 | 0.0400943396226415 | 1 |
| KCNQ1-201 | KCNQ1 | P51787 | Potassium voltage-gated channel subfamily KQT member 1 | chr11 | GO:0008217 | Not Cancer Driver | No | 55 | 0.0813609467455621 | 219 | 14 | 0.0207100591715976 | 109 |
| LEP-201 | LEP | P41159 | Leptin | chr7 | GO:0008217 | Not Cancer Driver | No | 20 | 0.1197604790419161 | 0 | 0 | 0.0 | 2 |
| LNPEP-201 | LNPEP | Q9UIQ6 | Leucyl-cystinyl aminopeptidase | chr5 | GO:0008217 | Not Cancer Driver | No | 80 | 0.0780487804878048 | 103 | 5 | 0.0048780487804878 | 0 |
| LRP5-201 | LRP5 | O75197 | Low-density lipoprotein receptor-related protein 5 | chr11 | GO:0008217 | Not Cancer Driver | No | 196 | 0.1213622291021671 | 189 | 24 | 0.014860681114551 | 54 |
| MC3R-201 | MC3R | P41968 | Melanocortin receptor 3 | chr20 | GO:0008217 | Not Cancer Driver | No | 83 | 0.2569659442724458 | 0 | 0 | 0.0 | 0 |
| MYH6-201 | MYH6 | P13533 | Myosin-6 | chr14 | GO:0008217 | Not Cancer Driver | No | 310 | 0.1598762248581743 | 1121 | 190 | 0.0979886539453326 | 7 |
| NOS3-201 | NOS3 | P29474 | Nitric oxide synthase 3 | chr7 | GO:0008217 | Not Cancer Driver | No | 143 | 0.1188694929343308 | 349 | 30 | 0.0249376558603491 | 0 |
| NOX1-204 | NOX1 | Q9Y5S8 | NADPH oxidase 1 | chrX | GO:0008217 | Not Cancer Driver | No | 76 | 0.1347517730496454 | 18 | 5 | 0.0088652482269503 | 0 |
| NPPA-202 | NPPA | P01160 | Natriuretic peptides A | chr1 | GO:0008217 | Not Cancer Driver | No | 21 | 0.1390728476821192 | 72 | 13 | 0.086092715231788 | 1 |
| NPPB-201 | NPPB | P16860 | Natriuretic peptides B | chr1 | GO:0008217 | Not Cancer Driver | No | 25 | 0.1865671641791045 | 104 | 22 | 0.1641791044776119 | 0 |
| NPR1-202 | NPR1 | P16066 | Atrial natriuretic peptide receptor 1 | chr1 | GO:0008217 | Not Cancer Driver | No | 105 | 0.0989632422243166 | 78 | 16 | 0.0150801131008482 | 0 |
| NPR2-201 | NPR2 | P20594 | Atrial natriuretic peptide receptor 2 | chr9 | GO:0008217 | Not Cancer Driver | No | 106 | 0.1012416427889207 | 91 | 9 | 0.0085959885386819 | 20 |
| NPR3-201 | NPR3 | P17342 | Atrial natriuretic peptide receptor 3 | chr5 | GO:0008217 | Not Cancer Driver | No | 79 | 0.1460258780036968 | 58 | 7 | 0.0129390018484288 | 2 |
| NPY-201 | NPY | P01303 | Pro-neuropeptide Y | chr7 | GO:0008217 | Not Cancer Driver | No | 29 | 0.2989690721649484 | 46 | 20 | 0.2061855670103092 | 0 |
| NPY1R-201 | NPY1R | P25929 | Neuropeptide Y receptor type 1 | chr4 | GO:0008217 | Not Cancer Driver | No | 89 | 0.2317708333333333 | 4 | 0 | 0.0 | 0 |
| P2RX1-201 | P2RX1 | P51575 | P2X purinoceptor 1 | chr17 | GO:0008217 | Not Cancer Driver | No | 42 | 0.1052631578947368 | 14 | 0 | 0.0 | 0 |
| P2RX4-202 | P2RX4 | Q99571 | P2X purinoceptor 4 | chr12 | GO:0008217 | Not Cancer Driver | No | 20 | 0.0515463917525773 | 0 | 0 | 0.0 | 0 |
| POMC-203 | POMC | P01189 | Pro-opiomelanocortin | chr2 | GO:0008217 | Not Cancer Driver | No | 28 | 0.1048689138576779 | 200 | 23 | 0.0861423220973782 | 0 |
| PPARG-201 | PPARG | P37231 | Peroxisome proliferator-activated receptor gamma | chr3 | GO:0008217 | Census | Yes | 60 | 0.1188118811881188 | 44 | 3 | 0.0059405940594059 | 3 |
| PTGS1-202 | PTGS1 | P23219 | Prostaglandin G/H synthase 1 | chr9 | GO:0008217 | Not Cancer Driver | No | 92 | 0.1535893155258764 | 28 | 3 | 0.005008347245409 | 0 |
| PTGS2-201 | PTGS2 | P35354 | Prostaglandin G/H synthase 2 | chr1 | GO:0008217 | Not Cancer Driver | No | 68 | 0.1125827814569536 | 31 | 4 | 0.0066225165562913 | 0 |
| RAMP2-201 | RAMP2 | O60895 | Receptor activity-modifying protein 2 | chr17 | GO:0008217 | Not Cancer Driver | No | 13 | 0.0742857142857142 | 34 | 4 | 0.0228571428571428 | 0 |
| REN-201 | REN | P00797 | Renin | chr1 | GO:0008217 | Not Cancer Driver | No | 46 | 0.1133004926108374 | 10 | 0 | 0.0 | 3 |
| RENBP-202 | RENBP | P51606 | N-acylglucosamine 2-epimerase | chrX | GO:0008217 | Not Cancer Driver | No | 53 | 0.1241217798594847 | 65 | 8 | 0.018735362997658 | 0 |
| SCNN1A-201 | SCNN1A | P37088 | Amiloride-sensitive sodium channel subunit alpha | chr12 | GO:0008217 | Not Cancer Driver | No | 66 | 0.0986547085201793 | 148 | 17 | 0.0254110612855007 | 5 |
| SCNN1B-202 | SCNN1B | P51168 | Amiloride-sensitive sodium channel subunit beta | chr16 | GO:0008217 | Not Cancer Driver | No | 64 | 0.1 | 62 | 4 | 0.00625 | 12 |
| SCNN1D-205 | SCNN1D | P51172 | Amiloride-sensitive sodium channel subunit delta | chr1 | GO:0008217 | Not Cancer Driver | No | 50 | 0.0623441396508728 | 212 | 9 | 0.0112219451371571 | 0 |
| SCNN1G-201 | SCNN1G | P51170 | Amiloride-sensitive sodium channel subunit gamma | chr16 | GO:0008217 | Not Cancer Driver | No | 105 | 0.1617873651771957 | 57 | 8 | 0.012326656394453 | 0 |
| SGK1-201 | SGK1 | O00141 | Serine/threonine-protein kinase Sgk1 | chr6 | GO:0008217 | Census, Compendium | Yes | 43 | 0.099767981438515 | 86 | 13 | 0.0301624129930394 | 0 |
| SOD1-201 | SOD1 | P00441 | Superoxide dismutase [Cu-Zn] | chr21 | GO:0008217 | Not Cancer Driver | No | 14 | 0.0909090909090909 | 94 | 9 | 0.0584415584415584 | 57 |
| SOD2-210 | SOD2 | P04179 | Superoxide dismutase [Mn], mitochondrial | chr6 | GO:0008217 | Not Cancer Driver | No | 21 | 0.0945945945945946 | 25 | 3 | 0.0135135135135135 | 0 |
| STK39-201 | STK39 | Q9UEW8 | STE20/SPS1-related proline-alanine-rich protein kinase | chr2 | GO:0008217 | Not Cancer Driver | No | 42 | 0.0770642201834862 | 183 | 13 | 0.0238532110091743 | 0 |
| TAC4-202 | TAC4 | Q86UU9 | Tachykinin-4 | chr17 | GO:0008217 | Not Cancer Driver | No | 11 | 0.0973451327433628 | 27 | 5 | 0.0442477876106194 | 0 |
| UMOD-202 | UMOD | P07911 | Uromodulin | chr16 | GO:0008217 | Not Cancer Driver | No | 102 | 0.159375 | 12 | 0 | 0.0 | 33 |
| UTS2-202 | UTS2 | O95399 | Urotensin-2 | chr1 | GO:0008217 | Not Cancer Driver | No | 10 | 0.0806451612903225 | 0 | 0 | 0.0 | 0 |
| UTS2B-201 | UTS2B | Q765I0 | Urotensin-2B | chr3 | GO:0008217 | Not Cancer Driver | No | 13 | 0.1092436974789916 | 2 | 0 | 0.0 | 0 |
| UTS2R-201 | UTS2R | Q9UKP6 | Urotensin-2 receptor | chr17 | GO:0008217 | Not Cancer Driver | No | 38 | 0.0976863753213367 | 74 | 4 | 0.0102827763496143 | 0 |
| WNK4-201 | WNK4 | Q96J92 | Serine/threonine-protein kinase WNK4 | chr17 | GO:0008217 | Compendium | Yes | 134 | 0.1078037007240547 | 921 | 98 | 0.078841512469831 | 4 |