Total number of protein in "GO:0008233" GO term: 87
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACE-202 | ACE | P12821 | Angiotensin-converting enzyme | chr17 | GO:0008233 | Not Cancer Driver | No | 152 | 0.116385911179173 | 87 | 5 | 0.0038284839203675 | 0 |
| ADAM17-201 | ADAM17 | P78536 | Disintegrin and metalloproteinase domain-containing protein 17 | chr2 | GO:0008233 | Not Cancer Driver | No | 63 | 0.0764563106796116 | 182 | 17 | 0.020631067961165 | 0 |
| ADAMTS4-202 | ADAMTS4 | O75173 | A disintegrin and metalloproteinase with thrombospondin motifs 4 | chr1 | GO:0008233 | Not Cancer Driver | No | 102 | 0.1218637992831541 | 160 | 19 | 0.022700119474313 | 0 |
| ADAMTS5-201 | ADAMTS5 | Q9UNA0 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | chr21 | GO:0008233 | Not Cancer Driver | No | 173 | 0.1860215053763441 | 148 | 23 | 0.0247311827956989 | 0 |
| AZU1-201 | AZU1 | P20160 | Azurocidin | chr19 | GO:0008233 | Not Cancer Driver | No | 34 | 0.1354581673306772 | 53 | 7 | 0.0278884462151394 | 0 |
| BACE1-201 | BACE1 | P56817 | Beta-secretase 1 | chr11 | GO:0008233 | Not Cancer Driver | No | 34 | 0.0678642714570858 | 53 | 2 | 0.0039920159680638 | 0 |
| BAP1-202 | BAP1 | Q92560 | Ubiquitin carboxyl-terminal hydrolase BAP1 | chr3 | GO:0008233 | Census, Compendium | Yes | 116 | 0.1591220850480109 | 419 | 42 | 0.0576131687242798 | 4 |
| BMP1-202 | BMP1 | P13497 | Bone morphogenetic protein 1 | chr8 | GO:0008233 | Not Cancer Driver | No | 93 | 0.0943204868154158 | 154 | 23 | 0.0233265720081135 | 3 |
| CAPN1-201 | CAPN1 | P07384 | Calpain-1 catalytic subunit | chr11 | GO:0008233 | Not Cancer Driver | No | 51 | 0.0714285714285714 | 32 | 0 | 0.0 | 1 |
| CAPN11-201 | CAPN11 | Q9UMQ6 | Calpain-11 | chr6 | GO:0008233 | Not Cancer Driver | No | 70 | 0.094722598105548 | 103 | 10 | 0.013531799729364 | 0 |
| CAPN3-205 | CAPN3 | P20807 | Calpain-3 | chr15 | GO:0008233 | Not Cancer Driver | No | 79 | 0.0962241169305724 | 169 | 8 | 0.0097442143727162 | 46 |
| CARD8-231 | CARD8 | Q9Y2G2 | Caspase recruitment domain-containing protein 8 | chr19 | GO:0008233 | Not Cancer Driver | No | 41 | 0.0763500931098696 | 130 | 5 | 0.0093109869646182 | 1 |
| CASP3-201 | CASP3 | P42574 | Caspase-3 | chr4 | GO:0008233 | Census | Yes | 19 | 0.0685920577617328 | 64 | 1 | 0.003610108303249 | 0 |
| CASP7-203 | CASP7 | P55210 | Caspase-7 | chr10 | GO:0008233 | Not Cancer Driver | No | 28 | 0.0924092409240924 | 75 | 7 | 0.0231023102310231 | 0 |
| CASP8-218 | CASP8 | Q14790 | Caspase-8 | chr2 | GO:0008233 | Census, Compendium | Yes | 116 | 0.2421711899791231 | 106 | 11 | 0.022964509394572 | 1 |
| CASP9-201 | CASP9 | P55211 | Caspase-9 | chr1 | GO:0008233 | Census | Yes | 26 | 0.0625 | 71 | 7 | 0.016826923076923 | 0 |
| CELA3B-201 | CELA3B | P08861 | Chymotrypsin-like elastase family member 3B | chr1 | GO:0008233 | Not Cancer Driver | No | 40 | 0.1481481481481481 | 21 | 7 | 0.0259259259259259 | 0 |
| CFAP44-202 | CFAP44 | Q96MT7 | Cilia- and flagella-associated protein 44 | chr3 | GO:0008233 | Not Cancer Driver | No | 135 | 0.0728155339805825 | 618 | 37 | 0.0199568500539374 | 0 |
| CIROP-201 | CIROP | A0A1B0GTW7 | Ciliated left-right organizer metallopeptidase | chr14 | GO:0008233 | Not Cancer Driver | No | 0 | 0.0 | 161 | 0 | 0.0 | 0 |
| CLPP-201 | CLPP | Q16740 | ATP-dependent Clp protease proteolytic subunit, mitochondrial | chr19 | GO:0008233 | Not Cancer Driver | No | 15 | 0.0541516245487364 | 83 | 7 | 0.0252707581227436 | 3 |
| COPS6-201 | COPS6 | Q7L5N1 | COP9 signalosome complex subunit 6 | chr7 | GO:0008233 | Not Cancer Driver | No | 23 | 0.0703363914373088 | 30 | 4 | 0.0122324159021406 | 0 |
| CTRC-202 | CTRC | Q99895 | Chymotrypsin-C | chr1 | GO:0008233 | Not Cancer Driver | No | 30 | 0.1119402985074626 | 1 | 0 | 0.0 | 9 |
| CTSB-202 | CTSB | P07858 | Cathepsin B | chr8 | GO:0008233 | Not Cancer Driver | No | 36 | 0.1061946902654867 | 7 | 2 | 0.0058997050147492 | 0 |
| CTSD-201 | CTSD | P07339 | Cathepsin D | chr11 | GO:0008233 | Not Cancer Driver | No | 49 | 0.1189320388349514 | 6 | 2 | 0.0048543689320388 | 2 |
| CTSE-201 | CTSE | P14091 | Cathepsin E | chr1 | GO:0008233 | Not Cancer Driver | No | 40 | 0.101010101010101 | 23 | 2 | 0.005050505050505 | 0 |
| CTSG-201 | CTSG | P08311 | Cathepsin G | chr14 | GO:0008233 | Not Cancer Driver | No | 56 | 0.2196078431372549 | 81 | 25 | 0.0980392156862745 | 0 |
| CTSH-201 | CTSH | P09668 | Pro-cathepsin H | chr15 | GO:0008233 | Not Cancer Driver | No | 35 | 0.1044776119402985 | 4 | 0 | 0.0 | 0 |
| DCD-201 | DCD | P81605 | Dermcidin | chr12 | GO:0008233 | Not Cancer Driver | No | 19 | 0.1727272727272727 | 67 | 15 | 0.1363636363636363 | 0 |
| DHH-201 | DHH | O43323 | Desert hedgehog protein | chr12 | GO:0008233 | Not Cancer Driver | No | 28 | 0.0707070707070707 | 57 | 5 | 0.0126262626262626 | 1 |
| ELANE-201 | ELANE | P08246 | Neutrophil elastase | chr19 | GO:0008233 | Not Cancer Driver | No | 31 | 0.1161048689138576 | 18 | 1 | 0.0037453183520599 | 65 |
| FAM111A-213 | FAM111A | Q96PZ2 | Serine protease FAM111A | chr11 | GO:0008233 | Not Cancer Driver | No | 53 | 0.0867430441898527 | 169 | 17 | 0.027823240589198 | 5 |
| FAM111B-201 | FAM111B | Q6SJ93 | Serine protease FAM111B | chr11 | GO:0008233 | Not Cancer Driver | No | 57 | 0.0776566757493188 | 190 | 11 | 0.0149863760217983 | 3 |
| FAP-201 | FAP | Q12884 | Prolyl endopeptidase FAP | chr2 | GO:0008233 | Not Cancer Driver | No | 127 | 0.1671052631578947 | 6 | 2 | 0.0026315789473684 | 0 |
| FOLH1-201 | FOLH1 | Q04609 | Glutamate carboxypeptidase 2 | chr11 | GO:0008233 | Not Cancer Driver | No | 161 | 0.2146666666666666 | 44 | 11 | 0.0146666666666666 | 0 |
| FURIN-201 | FURIN | P09958 | Furin | chr15 | GO:0008233 | Not Cancer Driver | No | 72 | 0.0906801007556675 | 283 | 30 | 0.0377833753148614 | 0 |
| HABP2-201 | HABP2 | Q14520 | Hyaluronan-binding protein 2 | chr10 | GO:0008233 | Not Cancer Driver | No | 62 | 0.1107142857142857 | 55 | 3 | 0.0053571428571428 | 1 |
| HM13-201 | HM13 | Q8TCT9 | Minor histocompatibility antigen H13 | chr20 | GO:0008233 | Not Cancer Driver | No | 30 | 0.0795755968169761 | 61 | 3 | 0.0079575596816976 | 0 |
| HMCES-201 | HMCES | Q96FZ2 | Abasic site processing protein HMCES | chr3 | GO:0008233 | Not Cancer Driver | No | 34 | 0.096045197740113 | 131 | 14 | 0.03954802259887 | 0 |
| HPN-210 | HPN | P05981 | Serine protease hepsin | chr19 | GO:0008233 | Not Cancer Driver | No | 49 | 0.1175059952038369 | 12 | 2 | 0.0047961630695443 | 0 |
| HTRA2-201 | HTRA2 | O43464 | Serine protease HTRA2, mitochondrial | chr2 | GO:0008233 | Compendium | Yes | 33 | 0.0720524017467248 | 127 | 7 | 0.0152838427947598 | 2 |
| IHH-201 | IHH | Q14623 | Indian hedgehog protein | chr2 | GO:0008233 | Not Cancer Driver | No | 50 | 0.121654501216545 | 111 | 14 | 0.0340632603406326 | 5 |
| IMMP2L-202 | IMMP2L | Q96T52 | Mitochondrial inner membrane protease subunit 2 | chr7 | GO:0008233 | Not Cancer Driver | No | 32 | 0.1828571428571428 | 29 | 6 | 0.0342857142857142 | 0 |
| KLK12-208 | KLK12 | Q9UKR0 | Kallikrein-12 | chr19 | GO:0008233 | Not Cancer Driver | No | 27 | 0.1088709677419354 | 0 | 0 | 0.0 | 0 |
| KLK5-201 | KLK5 | Q9Y337 | Kallikrein-5 | chr19 | GO:0008233 | Not Cancer Driver | No | 54 | 0.1843003412969283 | 75 | 14 | 0.0477815699658703 | 0 |
| KLK7-205 | KLK7 | P49862 | Kallikrein-7 | chr19 | GO:0008233 | Not Cancer Driver | No | 33 | 0.1304347826086956 | 38 | 5 | 0.0197628458498023 | 0 |
| KY-201 | KY | Q8NBH2 | Kyphoscoliosis peptidase | chr3 | GO:0008233 | Not Cancer Driver | No | 74 | 0.1119515885022692 | 140 | 20 | 0.0302571860816944 | 0 |
| LACTB-201 | LACTB | P83111 | Serine beta-lactamase-like protein LACTB, mitochondrial | chr15 | GO:0008233 | Not Cancer Driver | No | 29 | 0.053016453382084 | 123 | 2 | 0.0036563071297989 | 0 |
| LAP3-201 | LAP3 | P28838 | Cytosol aminopeptidase | chr4 | GO:0008233 | Not Cancer Driver | No | 39 | 0.0751445086705202 | 100 | 8 | 0.0154142581888246 | 0 |
| LGMN-201 | LGMN | Q99538 | Legumain | chr14 | GO:0008233 | Not Cancer Driver | No | 40 | 0.092378752886836 | 112 | 11 | 0.0254041570438799 | 0 |
| LMLN-204 | LMLN | Q96KR4 | Leishmanolysin-like peptidase | chr3 | GO:0008233 | Not Cancer Driver | No | 43 | 0.0628654970760233 | 46 | 3 | 0.0043859649122807 | 0 |
| LONP2-201 | LONP2 | Q86WA8 | Lon protease homolog 2, peroxisomal | chr16 | GO:0008233 | Not Cancer Driver | No | 85 | 0.0997652582159624 | 163 | 21 | 0.0246478873239436 | 0 |
| LTA4H-201 | LTA4H | P09960 | Leukotriene A-4 hydrolase | chr12 | GO:0008233 | Not Cancer Driver | No | 41 | 0.0671031096563011 | 39 | 4 | 0.0065466448445171 | 0 |
| MALT1-208 | MALT1 | Q9UDY8 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | chr18 | GO:0008233 | Census, Compendium | Yes | 55 | 0.0667475728155339 | 139 | 9 | 0.0109223300970873 | 1 |
| MASP1-203 | MASP1 | P48740 | Mannan-binding lectin serine protease 1 | chr3 | GO:0008233 | Not Cancer Driver | No | 98 | 0.1402002861230329 | 72 | 7 | 0.0100143061516452 | 0 |
| MASP2-201 | MASP2 | O00187 | Mannan-binding lectin serine protease 2 | chr1 | GO:0008233 | Not Cancer Driver | No | 76 | 0.1107871720116618 | 60 | 6 | 0.0087463556851311 | 2 |
| MMP1-201 | MMP1 | P03956 | Interstitial collagenase | chr11 | GO:0008233 | Not Cancer Driver | No | 65 | 0.138592750533049 | 114 | 16 | 0.0341151385927505 | 0 |
| MMP3-201 | MMP3 | P08254 | Stromelysin-1 | chr11 | GO:0008233 | Not Cancer Driver | No | 74 | 0.1551362683438155 | 66 | 13 | 0.0272536687631027 | 0 |
| MMP8-201 | MMP8 | P22894 | Neutrophil collagenase | chr11 | GO:0008233 | Not Cancer Driver | No | 62 | 0.1327623126338329 | 117 | 16 | 0.0342612419700214 | 0 |
| MMP9-201 | MMP9 | P14780 | Matrix metalloproteinase-9 | chr20 | GO:0008233 | Not Cancer Driver | No | 106 | 0.1499292786421499 | 124 | 24 | 0.0339462517680339 | 0 |
| MYRF-202 | MYRF | Q9Y2G1 | Myelin regulatory factor | chr11 | GO:0008233 | Not Cancer Driver | No | 86 | 0.0747176368375325 | 686 | 62 | 0.0538662033014769 | 2 |
| NAALADL1-204 | NAALADL1 | Q9UQQ1 | Aminopeptidase NAALADL1 | chr11 | GO:0008233 | Not Cancer Driver | No | 79 | 0.1067567567567567 | 136 | 11 | 0.0148648648648648 | 0 |
| NAPSA-201 | NAPSA | O96009 | Napsin-A | chr19 | GO:0008233 | Not Cancer Driver | No | 39 | 0.0928571428571428 | 14 | 0 | 0.0 | 0 |
| NLRP1-208 | NLRP1 | Q9C000 | NACHT, LRR and PYD domains-containing protein 1 | chr17 | GO:0008233 | Not Cancer Driver | No | 169 | 0.1147318397827562 | 341 | 45 | 0.0305498981670061 | 6 |
| NPEPL1-201 | NPEPL1 | Q8NDH3 | Probable aminopeptidase NPEPL1 | chr20 | GO:0008233 | Not Cancer Driver | No | 57 | 0.1089866156787763 | 26 | 2 | 0.0038240917782026 | 0 |
| PARK7-201 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | GO:0008233 | Not Cancer Driver | No | 8 | 0.0423280423280423 | 30 | 0 | 0.0 | 6 |
| PCSK5-205 | PCSK5 | Q92824 | Proprotein convertase subtilisin/kexin type 5 | chr9 | GO:0008233 | Not Cancer Driver | No | 259 | 0.139247311827957 | 170 | 20 | 0.010752688172043 | 0 |
| PCSK7-201 | PCSK7 | Q16549 | Proprotein convertase subtilisin/kexin type 7 | chr11 | GO:0008233 | Not Cancer Driver | No | 80 | 0.1019108280254777 | 267 | 24 | 0.0305732484076433 | 0 |
| PEPD-201 | PEPD | P12955 | Xaa-Pro dipeptidase | chr19 | GO:0008233 | Not Cancer Driver | No | 43 | 0.0872210953346856 | 18 | 1 | 0.0020283975659229 | 4 |
| PM20D1-201 | PM20D1 | Q6GTS8 | N-fatty-acyl-amino acid synthase/hydrolase PM20D1 | chr1 | GO:0008233 | Not Cancer Driver | No | 54 | 0.1075697211155378 | 43 | 7 | 0.0139442231075697 | 0 |
| PREPL-206 | PREPL | Q4J6C6 | Prolyl endopeptidase-like | chr2 | GO:0008233 | Not Cancer Driver | No | 89 | 0.1224209078404401 | 91 | 17 | 0.0233837689133425 | 0 |
| PRPF8-201 | PRPF8 | Q6P2Q9 | Pre-mRNA-processing-splicing factor 8 | chr17 | GO:0008233 | Not Cancer Driver | No | 202 | 0.086509635974304 | 226 | 24 | 0.0102783725910064 | 6 |
| PSMB11-201 | PSMB11 | A5LHX3 | Proteasome subunit beta type-11 | chr14 | GO:0008233 | Not Cancer Driver | No | 41 | 0.1366666666666666 | 71 | 10 | 0.0333333333333333 | 0 |
| PSMB5-202 | PSMB5 | P28074 | Proteasome subunit beta type-5 | chr14 | GO:0008233 | Not Cancer Driver | No | 31 | 0.11787072243346 | 9 | 0 | 0.0 | 0 |
| PSMD7-201 | PSMD7 | P51665 | 26S proteasome non-ATPase regulatory subunit 7 | chr16 | GO:0008233 | Not Cancer Driver | No | 24 | 0.074074074074074 | 70 | 3 | 0.0092592592592592 | 0 |
| REN-201 | REN | P00797 | Renin | chr1 | GO:0008233 | Not Cancer Driver | No | 46 | 0.1133004926108374 | 10 | 0 | 0.0 | 3 |
| SEC11A-201 | SEC11A | P67812 | Signal peptidase complex catalytic subunit SEC11A | chr15 | GO:0008233 | Not Cancer Driver | No | 15 | 0.0837988826815642 | 0 | 0 | 0.0 | 0 |
| SEC11C-204 | SEC11C | Q9BY50 | Signal peptidase complex catalytic subunit SEC11C | chr18 | GO:0008233 | Not Cancer Driver | No | 24 | 0.125 | 3 | 0 | 0.0 | 0 |
| SHH-201 | SHH | Q15465 | Sonic hedgehog protein | chr7 | GO:0008233 | Not Cancer Driver | No | 36 | 0.0779220779220779 | 139 | 11 | 0.0238095238095238 | 69 |
| SPG7-268 | SPG7 | Q9UQ90 | Paraplegin | chr16 | GO:0008233 | Not Cancer Driver | No | 76 | 0.0955974842767295 | 184 | 23 | 0.0289308176100628 | 4 |
| TGM2-201 | TGM2 | P21980 | Protein-glutamine gamma-glutamyltransferase 2 | chr20 | GO:0008233 | Not Cancer Driver | No | 82 | 0.1193595342066957 | 108 | 19 | 0.0276564774381368 | 0 |
| TMPRSS11D-201 | TMPRSS11D | O60235 | Transmembrane protease serine 11D | chr4 | GO:0008233 | Not Cancer Driver | No | 62 | 0.1483253588516746 | 26 | 3 | 0.0071770334928229 | 0 |
| TMPRSS5-201 | TMPRSS5 | Q9H3S3 | Transmembrane protease serine 5 | chr11 | GO:0008233 | Not Cancer Driver | No | 27 | 0.0590809628008752 | 33 | 1 | 0.0021881838074398 | 0 |
| TPP1-201 | TPP1 | O14773 | Tripeptidyl-peptidase 1 | chr11 | GO:0008233 | Not Cancer Driver | No | 56 | 0.0994671403197158 | 92 | 7 | 0.0124333925399644 | 34 |
| UCHL3-201 | UCHL3 | P15374 | Ubiquitin carboxyl-terminal hydrolase isozyme L3 | chr13 | GO:0008233 | Not Cancer Driver | No | 20 | 0.0869565217391304 | 61 | 1 | 0.0043478260869565 | 0 |
| UNC5CL-201 | UNC5CL | Q8IV45 | UNC5C-like protein | chr6 | GO:0008233 | Not Cancer Driver | No | 54 | 0.1042471042471042 | 70 | 10 | 0.0193050193050193 | 0 |
| USP1-201 | USP1 | O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | chr1 | GO:0008233 | Not Cancer Driver | No | 45 | 0.0573248407643312 | 405 | 20 | 0.0254777070063694 | 0 |
| USP25-201 | USP25 | Q9UHP3 | Ubiquitin carboxyl-terminal hydrolase 25 | chr21 | GO:0008233 | Not Cancer Driver | No | 89 | 0.0843601895734597 | 356 | 39 | 0.0369668246445497 | 0 |