Total number of protein in "GO:0008286" GO term: 70
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKT1-218 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0008286 | Census, Compendium | Yes | 99 | 0.20625 | 158 | 19 | 0.0395833333333333 | 4 |
| AKT2-206 | AKT2 | P31751 | RAC-beta serine/threonine-protein kinase | chr19 | GO:0008286 | Census | Yes | 57 | 0.1185031185031185 | 84 | 9 | 0.0187110187110187 | 2 |
| AP3S1-201 | AP3S1 | Q92572 | AP-3 complex subunit sigma-1 | chr5 | GO:0008286 | Not Cancer Driver | No | 20 | 0.1036269430051813 | 0 | 0 | 0.0 | 0 |
| APC-201 | APC | P25054 | Adenomatous polyposis coli protein | chr5 | GO:0008286 | Census, Compendium | Yes | 295 | 0.1037636299683433 | 2412 | 248 | 0.0872317973971157 | 22 |
| APPL1-201 | APPL1 | Q9UKG1 | DCC-interacting protein 13-alpha | chr3 | GO:0008286 | Not Cancer Driver | No | 35 | 0.0493653032440056 | 293 | 18 | 0.0253878702397743 | 1 |
| BAIAP2-202 | BAIAP2 | Q9UQB8 | Brain-specific angiogenesis inhibitor 1-associated protein 2 | chr17 | GO:0008286 | Not Cancer Driver | No | 60 | 0.108695652173913 | 332 | 43 | 0.0778985507246376 | 0 |
| BCAR1-201 | BCAR1 | P56945 | Breast cancer anti-estrogen resistance protein 1 | chr16 | GO:0008286 | Not Cancer Driver | No | 88 | 0.1011494252873563 | 681 | 64 | 0.0735632183908046 | 0 |
| BCAR3-201 | BCAR3 | O75815 | Breast cancer anti-estrogen resistance protein 3 | chr1 | GO:0008286 | Not Cancer Driver | No | 74 | 0.0896969696969696 | 397 | 34 | 0.0412121212121212 | 0 |
| C2CD5-201 | C2CD5 | Q86YS7 | C2 domain-containing protein 5 | chr12 | GO:0008286 | Not Cancer Driver | No | 82 | 0.082 | 251 | 21 | 0.021 | 0 |
| CAV2-201 | CAV2 | P51636 | Caveolin-2 | chr7 | GO:0008286 | Not Cancer Driver | No | 13 | 0.0802469135802469 | 5 | 2 | 0.0123456790123456 | 0 |
| COL6A1-201 | COL6A1 | P12109 | Collagen alpha-1(VI) chain | chr21 | GO:0008286 | Not Cancer Driver | No | 68 | 0.0661478599221789 | 436 | 23 | 0.0223735408560311 | 12 |
| CSRP3-201 | CSRP3 | P50461 | Cysteine and glycine-rich protein 3 | chr11 | GO:0008286 | Not Cancer Driver | No | 23 | 0.1185567010309278 | 31 | 1 | 0.0051546391752577 | 2 |
| DNAI1-201 | DNAI1 | Q9UI46 | Dynein axonemal intermediate chain 1 | chr9 | GO:0008286 | Not Cancer Driver | No | 82 | 0.117310443490701 | 296 | 34 | 0.0486409155937052 | 1 |
| EIF4EBP2-201 | EIF4EBP2 | Q13542 | Eukaryotic translation initiation factor 4E-binding protein 2 | chr10 | GO:0008286 | Not Cancer Driver | No | 13 | 0.1083333333333333 | 119 | 12 | 0.1 | 0 |
| ENST00000593731 | PIK3R2 | O00459 | Phosphatidylinositol 3-kinase regulatory subunit beta | chr19 | GO:0008286 | Not Cancer Driver | No | 83 | 0.114010989010989 | 418 | 40 | 0.0549450549450549 | 3 |
| FER-201 | FER | P16591 | Tyrosine-protein kinase Fer | chr5 | GO:0008286 | Not Cancer Driver | No | 70 | 0.0851581508515815 | 145 | 13 | 0.0158150851581508 | 0 |
| FOXC2-201 | FOXC2 | Q99958 | Forkhead box protein C2 | chr16 | GO:0008286 | Not Cancer Driver | No | 52 | 0.1037924151696606 | 370 | 31 | 0.06187624750499 | 1 |
| FOXO1-201 | FOXO1 | Q12778 | Forkhead box protein O1 | chr13 | GO:0008286 | Census, Compendium | Yes | 52 | 0.0793893129770992 | 586 | 51 | 0.0778625954198473 | 0 |
| FOXO4-202 | FOXO4 | P98177 | Forkhead box protein O4 | chrX | GO:0008286 | Census | Yes | 56 | 0.1108910891089108 | 441 | 45 | 0.0891089108910891 | 0 |
| GAB1-201 | GAB1 | Q13480 | GRB2-associated-binding protein 1 | chr4 | GO:0008286 | Not Cancer Driver | No | 54 | 0.0778097982708933 | 570 | 46 | 0.0662824207492795 | 1 |
| GPLD1-201 | GPLD1 | P80108 | Phosphatidylinositol-glycan-specific phospholipase D | chr6 | GO:0008286 | Not Cancer Driver | No | 117 | 0.1392857142857143 | 37 | 7 | 0.0083333333333333 | 0 |
| GPR21-201 | GPR21 | Q99679 | Probable G-protein coupled receptor 21 | chr9 | GO:0008286 | Not Cancer Driver | No | 24 | 0.0687679083094555 | 2 | 0 | 0.0 | 0 |
| GRB10-205 | GRB10 | Q13322 | Growth factor receptor-bound protein 10 | chr7 | GO:0008286 | Not Cancer Driver | No | 67 | 0.1127946127946128 | 222 | 30 | 0.0505050505050505 | 0 |
| GRB14-201 | GRB14 | Q14449 | Growth factor receptor-bound protein 14 | chr2 | GO:0008286 | Not Cancer Driver | No | 58 | 0.1074074074074074 | 117 | 7 | 0.0129629629629629 | 0 |
| GRB2-202 | GRB2 | P62993 | Growth factor receptor-bound protein 2 | chr17 | GO:0008286 | Not Cancer Driver | No | 21 | 0.0967741935483871 | 10 | 0 | 0.0 | 0 |
| GRB7-201 | GRB7 | Q14451 | Growth factor receptor-bound protein 7 | chr17 | GO:0008286 | Not Cancer Driver | No | 61 | 0.1146616541353383 | 134 | 18 | 0.0338345864661654 | 0 |
| GSK3A-201 | GSK3A | P49840 | Glycogen synthase kinase-3 alpha | chr19 | GO:0008286 | Not Cancer Driver | No | 33 | 0.0683229813664596 | 180 | 5 | 0.010351966873706 | 0 |
| GSK3B-201 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | GO:0008286 | Not Cancer Driver | No | 34 | 0.0809523809523809 | 148 | 6 | 0.0142857142857142 | 0 |
| HRAS-201 | HRAS | P01112 | GTPase HRas | chr11 | GO:0008286 | Census, Compendium | Yes | 129 | 0.6825396825396826 | 16 | 2 | 0.0105820105820105 | 10 |
| IDE-201 | IDE | P14735 | Insulin-degrading enzyme | chr10 | GO:0008286 | Not Cancer Driver | No | 65 | 0.0637880274779195 | 96 | 6 | 0.0058881256133464 | 0 |
| IGF1R-217 | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | GO:0008286 | Not Cancer Driver | No | 143 | 0.1046086320409656 | 265 | 30 | 0.021945866861741 | 6 |
| IGF2-205 | IGF2 | P01344 | Insulin-like growth factor II | chr11 | GO:0008286 | Not Cancer Driver | No | 32 | 0.1777777777777777 | 44 | 10 | 0.0555555555555555 | 0 |
| IGFBP1-201 | IGFBP1 | P08833 | Insulin-like growth factor-binding protein 1 | chr7 | GO:0008286 | Not Cancer Driver | No | 29 | 0.1119691119691119 | 42 | 7 | 0.027027027027027 | 0 |
| INS-202 | INS | P01308 | Insulin | chr11 | GO:0008286 | Not Cancer Driver | No | 7 | 0.0636363636363636 | 5 | 1 | 0.009090909090909 | 19 |
| INSR-201 | INSR | P06213 | Insulin receptor | chr19 | GO:0008286 | Not Cancer Driver | No | 139 | 0.1005788712011577 | 282 | 37 | 0.0267727930535455 | 63 |
| INSRR-201 | INSRR | P14616 | Insulin receptor-related protein | chr1 | GO:0008286 | Not Cancer Driver | No | 213 | 0.164225134926754 | 229 | 34 | 0.0262143407864302 | 0 |
| IRS1-201 | IRS1 | P35568 | Insulin receptor substrate 1 | chr2 | GO:0008286 | Not Cancer Driver | No | 118 | 0.0950080515297906 | 1075 | 104 | 0.0837359098228663 | 2 |
| IRS2-201 | IRS2 | Q9Y4H2 | Insulin receptor substrate 2 | chr13 | GO:0008286 | Not Cancer Driver | No | 44 | 0.0328849028400597 | 1117 | 34 | 0.0254110612855007 | 0 |
| IRS4-202 | IRS4 | O14654 | Insulin receptor substrate 4 | chrX | GO:0008286 | Census, Compendium | Yes | 98 | 0.0779634049323786 | 801 | 80 | 0.0636435958631662 | 0 |
| MAPK1-201 | MAPK1 | P28482 | Mitogen-activated protein kinase 1 | chr22 | GO:0008286 | Census, Compendium | Yes | 52 | 0.1444444444444444 | 2 | 0 | 0.0 | 6 |
| MAPK3-201 | MAPK3 | P27361 | Mitogen-activated protein kinase 3 | chr16 | GO:0008286 | Not Cancer Driver | No | 32 | 0.0844327176781002 | 49 | 3 | 0.0079155672823219 | 0 |
| NAMPT-201 | NAMPT | P43490 | Nicotinamide phosphoribosyltransferase | chr7 | GO:0008286 | Not Cancer Driver | No | 39 | 0.0794297352342158 | 27 | 5 | 0.010183299389002 | 0 |
| NCOA5-201 | NCOA5 | Q9HCD5 | Nuclear receptor coactivator 5 | chr20 | GO:0008286 | Not Cancer Driver | No | 42 | 0.0725388601036269 | 482 | 31 | 0.0535405872193437 | 0 |
| NDEL1-201 | NDEL1 | Q9GZM8 | Nuclear distribution protein nudE-like 1 | chr17 | GO:0008286 | Not Cancer Driver | No | 23 | 0.0666666666666666 | 203 | 13 | 0.0376811594202898 | 0 |
| PDK2-203 | PDK2 | Q15119 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | chr17 | GO:0008286 | Not Cancer Driver | No | 32 | 0.0786240786240786 | 35 | 1 | 0.0024570024570024 | 0 |
| PDK4-201 | PDK4 | Q16654 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | chr7 | GO:0008286 | Not Cancer Driver | No | 45 | 0.1094890510948905 | 14 | 1 | 0.0024330900243309 | 0 |
| PDPK1-202 | PDPK1 | O15530 | 3-phosphoinositide-dependent protein kinase 1 | chr16 | GO:0008286 | Not Cancer Driver | No | 23 | 0.0413669064748201 | 121 | 9 | 0.0161870503597122 | 0 |
| PHIP-201 | PHIP | Q8WWQ0 | PH-interacting protein | chr6 | GO:0008286 | Not Cancer Driver | No | 152 | 0.0834706205381658 | 838 | 74 | 0.0406370126304228 | 0 |
| PIK3C2A-206 | PIK3C2A | O00443 | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | chr11 | GO:0008286 | Not Cancer Driver | No | 119 | 0.0705812574139976 | 351 | 24 | 0.0142348754448398 | 0 |
| PIK3CA-201 | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0008286 | Census, Compendium | Yes | 1425 | 1.3342696629213484 | 38 | 9 | 0.0084269662921348 | 44 |
| PIK3R1-211 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | GO:0008286 | Census, Compendium | Yes | 122 | 0.1685082872928177 | 271 | 50 | 0.0690607734806629 | 2 |
| PIK3R2-201 | PIK3R2 | O00459 | Phosphatidylinositol 3-kinase regulatory subunit beta | chr19 | GO:0008286 | Not Cancer Driver | No | 83 | 0.114010989010989 | 418 | 40 | 0.0549450549450549 | 3 |
| PIK3R3-201 | PIK3R3 | Q92569 | Phosphatidylinositol 3-kinase regulatory subunit gamma | chr1 | GO:0008286 | Not Cancer Driver | No | 42 | 0.0911062906724512 | 149 | 17 | 0.0368763557483731 | 0 |
| PTPN1-201 | PTPN1 | P18031 | Tyrosine-protein phosphatase non-receptor type 1 | chr20 | GO:0008286 | Not Cancer Driver | No | 36 | 0.0827586206896551 | 141 | 17 | 0.0390804597701149 | 0 |
| PTPN2-201 | PTPN2 | P17706 | Tyrosine-protein phosphatase non-receptor type 2 | chr18 | GO:0008286 | Not Cancer Driver | No | 39 | 0.0939759036144578 | 120 | 10 | 0.0240963855421686 | 0 |
| PTPRA-204 | PTPRA | P18433 | Receptor-type tyrosine-protein phosphatase alpha | chr20 | GO:0008286 | Not Cancer Driver | No | 72 | 0.0897755610972568 | 208 | 17 | 0.0211970074812967 | 0 |
| RAF1-201 | RAF1 | P04049 | RAF proto-oncogene serine/threonine-protein kinase | chr3 | GO:0008286 | Census, Compendium | Yes | 64 | 0.0987654320987654 | 169 | 30 | 0.0462962962962962 | 18 |
| RARRES2-201 | RARRES2 | Q99969 | Retinoic acid receptor responder protein 2 | chr7 | GO:0008286 | Not Cancer Driver | No | 10 | 0.0613496932515337 | 14 | 1 | 0.0061349693251533 | 0 |
| RHOQ-201 | RHOQ | P17081 | Rho-related GTP-binding protein RhoQ | chr2 | GO:0008286 | Not Cancer Driver | No | 19 | 0.0926829268292682 | 0 | 0 | 0.0 | 0 |
| SH2B2-201 | SH2B2 | O14492 | SH2B adapter protein 2 | chr7 | GO:0008286 | Not Cancer Driver | No | 32 | 0.050632911392405 | 356 | 12 | 0.0189873417721519 | 0 |
| SHC1-202 | SHC1 | P29353 | SHC-transforming protein 1 | chr1 | GO:0008286 | Not Cancer Driver | No | 58 | 0.0994854202401372 | 400 | 41 | 0.0703259005145797 | 0 |
| SLC2A8-203 | SLC2A8 | Q9NY64 | Solute carrier family 2, facilitated glucose transporter member 8 | chr9 | GO:0008286 | Not Cancer Driver | No | 22 | 0.0461215932914046 | 20 | 0 | 0.0 | 0 |
| SLC39A14-204 | SLC39A14 | Q15043 | Metal cation symporter ZIP14 | chr8 | GO:0008286 | Not Cancer Driver | No | 27 | 0.0548780487804878 | 42 | 3 | 0.0060975609756097 | 4 |
| SMARCC1-201 | SMARCC1 | Q92922 | SWI/SNF complex subunit SMARCC1 | chr3 | GO:0008286 | Not Cancer Driver | No | 80 | 0.0723981900452488 | 721 | 50 | 0.0452488687782805 | 2 |
| SORBS1-211 | SORBS1 | Q9BX66 | Sorbin and SH3 domain-containing protein 1 | chr10 | GO:0008286 | Not Cancer Driver | No | 123 | 0.0952012383900928 | 1116 | 101 | 0.0781733746130031 | 0 |
| SOS1-202 | SOS1 | Q07889 | Son of sevenless homolog 1 | chr2 | GO:0008286 | Compendium | Yes | 155 | 0.1162790697674418 | 459 | 47 | 0.0352588147036759 | 32 |
| SOS2-201 | SOS2 | Q07890 | Son of sevenless homolog 2 | chr14 | GO:0008286 | Not Cancer Driver | No | 123 | 0.0923423423423423 | 362 | 44 | 0.033033033033033 | 2 |
| SREBF1-201 | SREBF1 | P36956 | Sterol regulatory element-binding protein 1 | chr17 | GO:0008286 | Not Cancer Driver | No | 87 | 0.075850043591979 | 530 | 42 | 0.036617262423714 | 3 |
| STXBP4-201 | STXBP4 | Q6ZWJ1 | Syntaxin-binding protein 4 | chr17 | GO:0008286 | Not Cancer Driver | No | 58 | 0.104882459312839 | 212 | 20 | 0.0361663652802893 | 0 |
| ZNF106-201 | ZNF106 | Q9H2Y7 | Zinc finger protein 106 | chr15 | GO:0008286 | Not Cancer Driver | No | 115 | 0.0610727562400424 | 1494 | 87 | 0.046202867764206 | 0 |