Total number of protein in "GO:0008340" GO term: 35
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ATM-229 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0008340 | Census, Compendium | Yes | 358 | 0.1171465968586387 | 226 | 29 | 0.0094895287958115 | 41 |
| ATN1-202 | ATN1 | P54259 | Atrophin-1 | chr12 | GO:0008340 | Not Cancer Driver | No | 111 | 0.0932773109243697 | 1176 | 109 | 0.0915966386554621 | 5 |
| ATP8A2-203 | ATP8A2 | Q9NTI2 | Phospholipid-transporting ATPase IB | chr13 | GO:0008340 | Not Cancer Driver | No | 165 | 0.1388888888888889 | 78 | 8 | 0.0067340067340067 | 1 |
| B4GALNT1-201 | B4GALNT1 | Q00973 | Beta-1,4 N-acetylgalactosaminyltransferase 1 | chr12 | GO:0008340 | Not Cancer Driver | No | 63 | 0.1181988742964352 | 74 | 9 | 0.0168855534709193 | 2 |
| CGAS-201 | CGAS | Q8N884 | Cyclic GMP-AMP synthase | chr6 | GO:0008340 | Not Cancer Driver | No | 33 | 0.0632183908045977 | 175 | 6 | 0.0114942528735632 | 0 |
| COQ7-201 | COQ7 | Q99807 | 5-demethoxyubiquinone hydroxylase, mitochondrial | chr16 | GO:0008340 | Not Cancer Driver | No | 16 | 0.0737327188940092 | 5 | 0 | 0.0 | 1 |
| ERCC1-202 | ERCC1 | P07992 | DNA excision repair protein ERCC-1 | chr19 | GO:0008340 | Not Cancer Driver | No | 36 | 0.1212121212121212 | 107 | 14 | 0.0471380471380471 | 1 |
| ERCC2-204 | ERCC2 | P18074 | General transcription and DNA repair factor IIH helicase subunit XPD | chr19 | GO:0008340 | Census, Compendium | Yes | 103 | 0.1355263157894737 | 5 | 0 | 0.0 | 30 |
| GBA1-202 | GBA1 | P04062 | Lysosomal acid glucosylceramidase | chr1 | GO:0008340 | Not Cancer Driver | No | 60 | 0.1119402985074626 | 38 | 6 | 0.0111940298507462 | 157 |
| GHRHR-201 | GHRHR | Q02643 | Growth hormone-releasing hormone receptor | chr7 | GO:0008340 | Not Cancer Driver | No | 30 | 0.0709219858156028 | 3 | 0 | 0.0 | 5 |
| INPP5D-204 | INPP5D | Q92835 | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 | chr2 | GO:0008340 | Not Cancer Driver | No | 140 | 0.1177460050462573 | 579 | 75 | 0.0630782169890664 | 0 |
| KCNJ11-201 | KCNJ11 | Q14654 | ATP-sensitive inward rectifier potassium channel 11 | chr11 | GO:0008340 | Not Cancer Driver | No | 34 | 0.0871794871794871 | 20 | 1 | 0.0025641025641025 | 37 |
| KCNJ8-201 | KCNJ8 | Q15842 | ATP-sensitive inward rectifier potassium channel 8 | chr12 | GO:0008340 | Not Cancer Driver | No | 78 | 0.1839622641509433 | 69 | 17 | 0.0400943396226415 | 1 |
| KL-201 | KL | Q9UEF7 | Klotho | chr13 | GO:0008340 | Not Cancer Driver | No | 131 | 0.1294466403162055 | 105 | 4 | 0.0039525691699604 | 1 |
| LARGE1-202 | LARGE1 | O95461 | Xylosyl- and glucuronyltransferase LARGE1 | chr22 | GO:0008340 | Not Cancer Driver | No | 109 | 0.1441798941798941 | 92 | 16 | 0.0211640211640211 | 4 |
| LEP-201 | LEP | P41159 | Leptin | chr7 | GO:0008340 | Not Cancer Driver | No | 20 | 0.1197604790419161 | 0 | 0 | 0.0 | 2 |
| LIPA-202 | LIPA | P38571 | Lysosomal acid lipase/cholesteryl ester hydrolase | chr10 | GO:0008340 | Not Cancer Driver | No | 30 | 0.075187969924812 | 13 | 1 | 0.0025062656641604 | 3 |
| LRRK2-201 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | GO:0008340 | Not Cancer Driver | No | 402 | 0.1590819153146023 | 91 | 13 | 0.0051444400474871 | 20 |
| MSH2-201 | MSH2 | P43246 | DNA mismatch repair protein Msh2 | chr2 | GO:0008340 | Census | Yes | 55 | 0.0588865096359743 | 37 | 1 | 0.0010706638115631 | 63 |
| MSH6-201 | MSH6 | P52701 | DNA mismatch repair protein Msh6 | chr2 | GO:0008340 | Census | Yes | 92 | 0.0676470588235294 | 389 | 26 | 0.0191176470588235 | 6 |
| NAGLU-201 | NAGLU | P54802 | Alpha-N-acetylglucosaminidase | chr17 | GO:0008340 | Not Cancer Driver | No | 57 | 0.0767160161507402 | 18 | 0 | 0.0 | 61 |
| PRDM2-202 | PRDM2 | Q13029 | PR domain zinc finger protein 2 | chr1 | GO:0008340 | Census, Compendium | Yes | 93 | 0.0541327124563445 | 1347 | 79 | 0.0459837019790454 | 0 |
| RAD54B-202 | RAD54B | Q9Y620 | DNA repair and recombination protein RAD54B | chr8 | GO:0008340 | Not Cancer Driver | No | 73 | 0.0802197802197802 | 122 | 9 | 0.0098901098901098 | 0 |
| RAD54L-201 | RAD54L | Q92698 | DNA repair and recombination protein RAD54-like | chr1 | GO:0008340 | Not Cancer Driver | No | 62 | 0.0829986613119143 | 125 | 11 | 0.0147255689424364 | 0 |
| SCN1A-224 | SCN1A | P35498 | Sodium channel protein type 1 subunit alpha | chr2 | GO:0008340 | Not Cancer Driver | No | 403 | 0.2005973120955699 | 457 | 104 | 0.0517670482827277 | 350 |
| SCN2A-202 | SCN2A | Q99250 | Sodium channel protein type 2 subunit alpha | chr2 | GO:0008340 | Not Cancer Driver | No | 363 | 0.1810473815461346 | 436 | 92 | 0.0458852867830423 | 73 |
| SGSH-201 | SGSH | P51688 | N-sulphoglucosamine sulphohydrolase | chr17 | GO:0008340 | Not Cancer Driver | No | 40 | 0.0796812749003984 | 44 | 2 | 0.0039840637450199 | 49 |
| SIRT6-202 | SIRT6 | Q8N6T7 | NAD-dependent protein deacylase sirtuin-6 | chr19 | GO:0008340 | Not Cancer Driver | No | 24 | 0.0676056338028169 | 165 | 6 | 0.0169014084507042 | 0 |
| SOD1-201 | SOD1 | P00441 | Superoxide dismutase [Cu-Zn] | chr21 | GO:0008340 | Not Cancer Driver | No | 14 | 0.0909090909090909 | 94 | 9 | 0.0584415584415584 | 57 |
| TFCP2L1-201 | TFCP2L1 | Q9NZI6 | Transcription factor CP2-like protein 1 | chr2 | GO:0008340 | Not Cancer Driver | No | 50 | 0.104384133611691 | 141 | 19 | 0.0396659707724425 | 0 |
| TP53-201 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0008340 | Census, Compendium | Yes | 2742 | 6.977099236641221 | 282 | 1364 | 3.470737913486005 | 60 |
| TP63-201 | TP63 | Q9H3D4 | Tumor protein 63 | chr3 | GO:0008340 | Census, Compendium | Yes | 198 | 0.2911764705882353 | 398 | 120 | 0.1764705882352941 | 21 |
| TREX1-205 | TREX1 | Q9NSU2 | Three-prime repair exonuclease 1 | chr3 | GO:0008340 | Not Cancer Driver | No | 24 | 0.0764331210191082 | 98 | 7 | 0.0222929936305732 | 17 |
| WRN-201 | WRN | Q14191 | Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN | chr8 | GO:0008340 | Census, Compendium | Yes | 133 | 0.092877094972067 | 374 | 29 | 0.0202513966480446 | 2 |
| ZMPSTE24-201 | ZMPSTE24 | O75844 | CAAX prenyl protease 1 homolog | chr1 | GO:0008340 | Not Cancer Driver | No | 46 | 0.0968421052631579 | 23 | 0 | 0.0 | 3 |