Total number of protein in "GO:0008542" GO term: 49
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCA7-201 | ABCA7 | Q8IZY2 | Phospholipid-transporting ATPase ABCA7 | chr19 | GO:0008542 | Not Cancer Driver | No | 171 | 0.0796831314072693 | 405 | 22 | 0.0102516309412861 | 1 |
| ABCC8-202 | ABCC8 | Q09428 | ATP-binding cassette sub-family C member 8 | chr11 | GO:0008542 | Not Cancer Driver | No | 186 | 0.1176470588235294 | 136 | 18 | 0.0113851992409867 | 88 |
| ADAM2-201 | ADAM2 | Q99965 | Disintegrin and metalloproteinase domain-containing protein 2 | chr8 | GO:0008542 | Not Cancer Driver | No | 159 | 0.2163265306122449 | 18 | 0 | 0.0 | 0 |
| APP-201 | APP | P05067 | Amyloid-beta precursor protein | chr21 | GO:0008542 | Not Cancer Driver | No | 94 | 0.122077922077922 | 419 | 52 | 0.0675324675324675 | 12 |
| ATP1A2-201 | ATP1A2 | P50993 | Sodium/potassium-transporting ATPase subunit alpha-2 | chr1 | GO:0008542 | Not Cancer Driver | No | 162 | 0.1588235294117647 | 162 | 21 | 0.0205882352941176 | 14 |
| B3GAT1-201 | B3GAT1 | Q9P2W7 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 | chr11 | GO:0008542 | Not Cancer Driver | No | 59 | 0.1766467065868263 | 93 | 24 | 0.0718562874251497 | 0 |
| B4GALT2-203 | B4GALT2 | O60909 | Beta-1,4-galactosyltransferase 2 | chr1 | GO:0008542 | Not Cancer Driver | No | 34 | 0.0913978494623656 | 105 | 7 | 0.0188172043010752 | 0 |
| BRAF-220 | BRAF | P15056 | Serine/threonine-protein kinase B-raf | chr7 | GO:0008542 | Census, Compendium | Yes | 755 | 0.9856396866840732 | 311 | 30 | 0.0391644908616188 | 35 |
| CDK5-204 | CDK5 | Q00535 | Cyclin-dependent kinase 5 | chr7 | GO:0008542 | Not Cancer Driver | No | 38 | 0.1301369863013698 | 5 | 0 | 0.0 | 0 |
| CHRNB2-201 | CHRNB2 | P17787 | Neuronal acetylcholine receptor subunit beta-2 | chr1 | GO:0008542 | Not Cancer Driver | No | 72 | 0.1434262948207171 | 23 | 1 | 0.0019920318725099 | 1 |
| COMT-202 | COMT | P21964 | Catechol O-methyltransferase | chr22 | GO:0008542 | Not Cancer Driver | No | 16 | 0.059040590405904 | 5 | 0 | 0.0 | 0 |
| CTNS-201 | CTNS | O60931 | Cystinosin | chr17 | GO:0008542 | Not Cancer Driver | No | 25 | 0.0681198910081744 | 0 | 0 | 0.0 | 28 |
| DBH-202 | DBH | P09172 | Dopamine beta-hydroxylase | chr9 | GO:0008542 | Not Cancer Driver | No | 102 | 0.1653160453808752 | 72 | 18 | 0.0291734197730956 | 3 |
| DDHD2-201 | DDHD2 | O94830 | Phospholipase DDHD2 | chr8 | GO:0008542 | Not Cancer Driver | No | 64 | 0.090014064697609 | 169 | 12 | 0.0168776371308016 | 1 |
| DRD1-201 | DRD1 | P21728 | D(1A) dopamine receptor | chr5 | GO:0008542 | Not Cancer Driver | No | 49 | 0.1098654708520179 | 30 | 3 | 0.0067264573991031 | 0 |
| DRD2-202 | DRD2 | P14416 | D(2) dopamine receptor | chr11 | GO:0008542 | Not Cancer Driver | No | 91 | 0.2054176072234763 | 124 | 31 | 0.0699774266365688 | 0 |
| DRD3-202 | DRD3 | P35462 | D(3) dopamine receptor | chr3 | GO:0008542 | Not Cancer Driver | No | 67 | 0.1675 | 45 | 15 | 0.0375 | 0 |
| FOXB1-201 | FOXB1 | Q99853 | Forkhead box protein B1 | chr15 | GO:0008542 | Not Cancer Driver | No | 25 | 0.0769230769230769 | 114 | 4 | 0.0123076923076923 | 0 |
| GRIN1-208 | GRIN1 | Q05586 | Glutamate receptor ionotropic, NMDA 1 | chr9 | GO:0008542 | Not Cancer Driver | No | 71 | 0.0756929637526652 | 190 | 8 | 0.0085287846481876 | 12 |
| GRIN2A-201 | GRIN2A | Q12879 | Glutamate receptor ionotropic, NMDA 2A | chr16 | GO:0008542 | Census, Compendium | Yes | 439 | 0.2998633879781421 | 507 | 172 | 0.1174863387978142 | 32 |
| HIF1A-202 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:0008542 | Census | Yes | 54 | 0.0653753026634382 | 436 | 28 | 0.0338983050847457 | 0 |
| HMGCR-201 | HMGCR | P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | chr5 | GO:0008542 | Not Cancer Driver | No | 52 | 0.0585585585585585 | 112 | 9 | 0.0101351351351351 | 0 |
| HRH1-203 | HRH1 | P35367 | Histamine H1 receptor | chr3 | GO:0008542 | Not Cancer Driver | No | 65 | 0.1334702258726899 | 122 | 16 | 0.0328542094455852 | 0 |
| IFT20-203 | IFT20 | Q8IY31 | Intraflagellar transport protein 20 homolog | chr17 | GO:0008542 | Not Cancer Driver | No | 11 | 0.0833333333333333 | 0 | 0 | 0.0 | 0 |
| ITGB1-201 | ITGB1 | P05556 | Integrin beta-1 | chr10 | GO:0008542 | Not Cancer Driver | No | 73 | 0.0914786967418546 | 84 | 8 | 0.0100250626566416 | 0 |
| KIT-201 | KIT | P10721 | Mast/stem cell growth factor receptor Kit | chr4 | GO:0008542 | Census, Compendium | Yes | 186 | 0.1905737704918032 | 84 | 24 | 0.0245901639344262 | 15 |
| KMT2A-201 | KMT2A | Q03164 | Histone-lysine N-methyltransferase 2A | chr11 | GO:0008542 | Census, Compendium | Yes | 342 | 0.0861678004535147 | 3148 | 263 | 0.0662635424540186 | 0 |
| KRAS-201 | KRAS | P01116 | GTPase KRas | chr12 | GO:0008542 | Census, Compendium | Yes | 771 | 4.079365079365079 | 7 | 2 | 0.0105820105820105 | 22 |
| LRRN4-201 | LRRN4 | Q8WUT4 | Leucine-rich repeat neuronal protein 4 | chr20 | GO:0008542 | Not Cancer Driver | No | 53 | 0.0716216216216216 | 259 | 21 | 0.0283783783783783 | 0 |
| MECP2-201 | MECP2 | P51608 | Methyl-CpG-binding protein 2 | chrX | GO:0008542 | Not Cancer Driver | No | 44 | 0.0905349794238683 | 482 | 43 | 0.088477366255144 | 32 |
| MEIS2-221 | MEIS2 | O14770 | Homeobox protein Meis2 | chr15 | GO:0008542 | Not Cancer Driver | No | 78 | 0.1635220125786163 | 358 | 66 | 0.1383647798742138 | 0 |
| NDRG4-255 | NDRG4 | Q9ULP0 | Protein NDRG4 | chr16 | GO:0008542 | Not Cancer Driver | No | 34 | 0.096590909090909 | 90 | 10 | 0.0284090909090909 | 0 |
| NETO1-201 | NETO1 | Q8TDF5 | Neuropilin and tolloid-like protein 1 | chr18 | GO:0008542 | Not Cancer Driver | No | 157 | 0.2945590994371482 | 103 | 32 | 0.0600375234521576 | 0 |
| NF1-202 | NF1 | P21359 | Neurofibromin | chr17 | GO:0008542 | Census, Compendium | Yes | 285 | 0.1003874603733709 | 406 | 36 | 0.0126805213103205 | 75 |
| NOG-201 | NOG | Q13253 | Noggin | chr17 | GO:0008542 | Not Cancer Driver | No | 15 | 0.0646551724137931 | 87 | 5 | 0.021551724137931 | 17 |
| NPS-201 | NPS | P0C0P6 | Neuropeptide S | chr10 | GO:0008542 | Not Cancer Driver | No | 19 | 0.2134831460674157 | 5 | 1 | 0.0112359550561797 | 0 |
| PDE1B-201 | PDE1B | Q01064 | Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | chr12 | GO:0008542 | Not Cancer Driver | No | 81 | 0.1511194029850746 | 132 | 24 | 0.044776119402985 | 0 |
| PDE8B-201 | PDE8B | O95263 | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B | chr5 | GO:0008542 | Not Cancer Driver | No | 104 | 0.1175141242937853 | 208 | 14 | 0.015819209039548 | 1 |
| PIAS1-201 | PIAS1 | O75925 | E3 SUMO-protein ligase PIAS1 | chr15 | GO:0008542 | Not Cancer Driver | No | 48 | 0.0737327188940092 | 241 | 25 | 0.0384024577572964 | 0 |
| PPP1R1B-201 | PPP1R1B | Q9UD71 | Protein phosphatase 1 regulatory subunit 1B | chr17 | GO:0008542 | Not Cancer Driver | No | 23 | 0.1127450980392156 | 204 | 23 | 0.1127450980392156 | 0 |
| RAG1-201 | RAG1 | P15918 | V(D)J recombination-activating protein 1 | chr11 | GO:0008542 | Not Cancer Driver | No | 161 | 0.1543624161073825 | 209 | 34 | 0.0325982742090124 | 35 |
| RGS14-201 | RGS14 | O43566 | Regulator of G-protein signaling 14 | chr5 | GO:0008542 | Not Cancer Driver | No | 46 | 0.0812720848056537 | 309 | 27 | 0.0477031802120141 | 0 |
| RIC8A-203 | RIC8A | Q9NPQ8 | Synembryn-A | chr11 | GO:0008542 | Not Cancer Driver | No | 54 | 0.1016949152542373 | 163 | 20 | 0.0376647834274952 | 0 |
| SLC7A11-201 | SLC7A11 | Q9UPY5 | Cystine/glutamate transporter | chr4 | GO:0008542 | Not Cancer Driver | No | 55 | 0.1097804391217564 | 15 | 1 | 0.0019960079840319 | 0 |
| SYNGAP1-229 | SYNGAP1 | Q96PV0 | Ras/Rap GTPase-activating protein SynGAP | chr6 | GO:0008542 | Not Cancer Driver | No | 113 | 0.0841399851079672 | 833 | 66 | 0.0491437081161578 | 4 |
| TAFA2-201 | TAFA2 | Q8N3H0 | Chemokine-like protein TAFA-2 | chr12 | GO:0008542 | Not Cancer Driver | No | 43 | 0.3282442748091603 | 4 | 1 | 0.0076335877862595 | 0 |
| TANC1-201 | TANC1 | Q9C0D5 | Protein TANC1 | chr2 | GO:0008542 | Not Cancer Driver | No | 172 | 0.092423428264374 | 914 | 75 | 0.0403009134873723 | 0 |
| TTC36-201 | TTC36 | A6NLP5 | Tetratricopeptide repeat protein 36 | chr11 | GO:0008542 | Not Cancer Driver | No | 9 | 0.0476190476190476 | 98 | 8 | 0.0423280423280423 | 0 |
| TUBA1A-202 | TUBA1A | Q71U36 | Tubulin alpha-1A chain | chr12 | GO:0008542 | Not Cancer Driver | No | 45 | 0.0997782705099778 | 52 | 6 | 0.0133037694013303 | 6 |