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Total number of protein in "GO:0008584" GO term:  105

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACE-202 ACE P12821 Angiotensin-converting enzyme chr17 GO:0008584 Not Cancer Driver No 152 0.116385911179173 87 5 0.0038284839203675 0
ADAM15-203 ADAM15 Q13444 Disintegrin and metalloproteinase domain-containing protein 15 chr1 GO:0008584 Not Cancer Driver No 76 0.0880648899188876 215 23 0.0266512166859791 0
ADAM18-201 ADAM18 Q9Y3Q7 Disintegrin and metalloproteinase domain-containing protein 18 chr8 GO:0008584 Not Cancer Driver No 184 0.2489851150202977 4 1 0.0013531799729364 0
ADAM2-201 ADAM2 Q99965 Disintegrin and metalloproteinase domain-containing protein 2 chr8 GO:0008584 Not Cancer Driver No 159 0.2163265306122449 18 0 0.0 0
ADAM20-201 ADAM20 O43506 Disintegrin and metalloproteinase domain-containing protein 20 chr14 GO:0008584 Not Cancer Driver No 69 0.0950413223140495 22 3 0.0041322314049586 0
ADAM21-201 ADAM21 Q9UKJ8 Disintegrin and metalloproteinase domain-containing protein 21 chr14 GO:0008584 Not Cancer Driver No 117 0.1620498614958448 4 0 0.0 0
ADAM29-201 ADAM29 Q9UKF5 Disintegrin and metalloproteinase domain-containing protein 29 chr4 GO:0008584 Not Cancer Driver No 180 0.2195121951219512 124 10 0.0121951219512195 0
ADAM30-201 ADAM30 Q9UKF2 Disintegrin and metalloproteinase domain-containing protein 30 chr1 GO:0008584 Not Cancer Driver No 101 0.1278481012658227 73 12 0.0151898734177215 0
ADAM32-201 ADAM32 Q8TC27 Disintegrin and metalloproteinase domain-containing protein 32 chr8 GO:0008584 Not Cancer Driver No 92 0.1168996188055908 88 10 0.0127064803049555 0
AGO4-201 AGO4 Q9HCK5 Protein argonaute-4 chr1 GO:0008584 Not Cancer Driver No 83 0.0963995354239256 183 22 0.0255516840882694 0
AKR1C3-201 AKR1C3 P42330 Aldo-keto reductase family 1 member C3 chr10 GO:0008584 Not Cancer Driver No 41 0.1269349845201238 11 1 0.0030959752321981 0
AMHR2-201 AMHR2 Q16671 Anti-Muellerian hormone type-2 receptor chr12 GO:0008584 Not Cancer Driver No 67 0.1169284467713787 118 9 0.0157068062827225 8
AR-201 AR P10275 Androgen receptor chrX GO:0008584 Census, Compendium Yes 116 0.1260869565217391 443 38 0.0413043478260869 144
ARID5B-201 ARID5B Q14865 AT-rich interactive domain-containing protein 5B chr10 GO:0008584 Not Cancer Driver No 133 0.1119528619528619 770 82 0.069023569023569 0
ASPM-203 ASPM Q8IZT6 Abnormal spindle-like microcephaly-associated protein chr1 GO:0008584 Not Cancer Driver No 380 0.1092896174863388 427 47 0.0135174000575208 0
ATN1-202 ATN1 P54259 Atrophin-1 chr12 GO:0008584 Not Cancer Driver No 111 0.0932773109243697 1176 109 0.0915966386554621 5
BCL2-201 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0008584 Census, Compendium Yes 21 0.0878661087866108 73 5 0.0209205020920502 0
BCL2L1-201 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 GO:0008584 Not Cancer Driver No 22 0.0944206008583691 55 2 0.0085836909871244 0
BCL2L11-204 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0008584 Not Cancer Driver No 37 0.1868686868686868 131 16 0.0808080808080808 0
BIK-201 BIK Q13323 Bcl-2-interacting killer chr22 GO:0008584 Not Cancer Driver No 10 0.0625 21 3 0.01875 0
BOK-201 BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:0008584 Not Cancer Driver No 5 0.0235849056603773 0 0 0.0 0
CBL-201 CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0008584 Census, Compendium Yes 84 0.0927152317880794 513 44 0.0485651214128035 4
CD2AP-201 CD2AP Q9Y5K6 CD2-associated protein chr6 GO:0008584 Not Cancer Driver No 51 0.0798122065727699 458 38 0.0594679186228482 0
CITED2-201 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0008584 Not Cancer Driver No 22 0.0814814814814814 232 19 0.0703703703703703 0
CRKL-201 CRKL P46109 Crk-like protein chr22 GO:0008584 Not Cancer Driver No 24 0.0792079207920792 160 17 0.0561056105610561 0
CSDE1-203 CSDE1 O75534 Cold shock domain-containing protein E1 chr1 GO:0008584 Not Cancer Driver No 82 0.1027568922305764 204 24 0.0300751879699248 0
CSMD1-217 CSMD1 Q96PZ7 CUB and sushi domain-containing protein 1 chr8 GO:0008584 Not Cancer Driver No 990 0.2777777777777778 234 63 0.0176767676767676 0
CTNNA1-201 CTNNA1 P35221 Catenin alpha-1 chr5 GO:0008584 Census Yes 90 0.0993377483443708 268 25 0.0275938189845474 4
CYP1B1-205 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0008584 Not Cancer Driver No 41 0.0755064456721915 33 3 0.005524861878453 39
DNAAF11-212 DNAAF11 Q86X45 Dynein axonemal assembly factor 11 chr8 GO:0008584 Not Cancer Driver No 83 0.1781115879828326 235 47 0.1008583690987124 2
EIF2S2-201 EIF2S2 P20042 Eukaryotic translation initiation factor 2 subunit 2 chr20 GO:0008584 Not Cancer Driver No 24 0.072072072072072 185 6 0.018018018018018 0
ERCC1-202 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0008584 Not Cancer Driver No 36 0.1212121212121212 107 14 0.0471380471380471 1
ESR1-201 ESR1 P03372 Estrogen receptor chr6 GO:0008584 Census, Compendium Yes 92 0.1546218487394958 198 19 0.0319327731092436 2
FANCA-202 FANCA O15360 Fanconi anemia group A protein chr16 GO:0008584 Census, Compendium Yes 121 0.0831615120274914 157 13 0.00893470790378 26
FGF9-201 FGF9 P31371 Fibroblast growth factor 9 chr13 GO:0008584 Not Cancer Driver No 33 0.1586538461538461 43 8 0.0384615384615384 1
FSHR-202 FSHR P23945 Follicle-stimulating hormone receptor chr2 GO:0008584 Not Cancer Driver No 177 0.2546762589928057 28 8 0.0115107913669064 15
GATA1-202 GATA1 P15976 Erythroid transcription factor chrX GO:0008584 Census, Compendium Yes 57 0.1380145278450363 242 34 0.0823244552058111 5
GATA3-201 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0008584 Census, Compendium Yes 99 0.2234762979683973 368 79 0.1783295711060948 2
GATA4-201 GATA4 P43694 Transcription factor GATA-4 chr8 GO:0008584 Not Cancer Driver No 34 0.0769230769230769 297 23 0.0520361990950226 21
GATA6-201 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0008584 Not Cancer Driver No 45 0.0756302521008403 478 39 0.0655462184873949 15
GFRA1-201 GFRA1 P56159 GDNF family receptor alpha-1 chr10 GO:0008584 Not Cancer Driver No 99 0.2129032258064516 43 9 0.0193548387096774 0
GJA1-201 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0008584 Not Cancer Driver No 62 0.1623036649214659 111 20 0.0523560209424083 43
HMGB2-201 HMGB2 P26583 High mobility group protein B2 chr4 GO:0008584 Not Cancer Driver No 26 0.124401913875598 207 26 0.124401913875598 0
HOXA10-201 HOXA10 P31260 Homeobox protein Hox-A10 chr7 GO:0008584 Not Cancer Driver No 30 0.073170731707317 339 22 0.0536585365853658 0
HOXA11-201 HOXA11 P31270 Homeobox protein Hox-A11 chr7 GO:0008584 Census, Compendium Yes 25 0.0798722044728434 205 16 0.0511182108626198 0
HOXA9-201 HOXA9 P31269 Homeobox protein Hox-A9 chr7 GO:0008584 Census Yes 41 0.150735294117647 189 30 0.1102941176470588 0
INHA-201 INHA P05111 Inhibin alpha chain chr2 GO:0008584 Not Cancer Driver No 43 0.1174863387978142 144 13 0.0355191256830601 0
INHBA-201 INHBA P08476 Inhibin beta A chain chr7 GO:0008584 Not Cancer Driver No 121 0.284037558685446 154 54 0.1267605633802817 0
INSL3-201 INSL3 P51460 Insulin-like 3 chr19 GO:0008584 Not Cancer Driver No 0 0.0 35 0 0.0 3
INSR-201 INSR P06213 Insulin receptor chr19 GO:0008584 Not Cancer Driver No 139 0.1005788712011577 282 37 0.0267727930535455 63
KCNE1-203 KCNE1 P15382 Potassium voltage-gated channel subfamily E member 1 chr21 GO:0008584 Not Cancer Driver No 24 0.1860465116279069 25 8 0.0620155038759689 9
KIT-201 KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0008584 Census, Compendium Yes 186 0.1905737704918032 84 24 0.0245901639344262 15
KITLG-205 KITLG P21583 Kit ligand chr12 GO:0008584 Not Cancer Driver No 38 0.1391941391941392 61 6 0.0219780219780219 1
KLHL10-201 KLHL10 Q6JEL2 Kelch-like protein 10 chr17 GO:0008584 Not Cancer Driver No 47 0.0773026315789473 24 1 0.0016447368421052 2
LHB-201 LHB P01229 Lutropin subunit beta chr19 GO:0008584 Not Cancer Driver No 14 0.0992907801418439 0 0 0.0 1
LHCGR-201 LHCGR P22888 Lutropin-choriogonadotropic hormone receptor chr2 GO:0008584 Not Cancer Driver No 140 0.2002861230329041 12 7 0.0100143061516452 24
LHX9-201 LHX9 Q9NQ69 LIM/homeobox protein Lhx9 chr1 GO:0008584 Not Cancer Driver No 75 0.1889168765743073 192 39 0.0982367758186398 0
LRP2-205 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0008584 Not Cancer Driver No 740 0.158968850698174 209 26 0.0055853920515574 1
MAMLD1-203 MAMLD1 Q13495 Mastermind-like domain-containing protein 1 chrX GO:0008584 Not Cancer Driver No 76 0.0981912144702842 745 71 0.0917312661498708 0
MAS1-202 MAS1 P04201 Proto-oncogene Mas chr6 GO:0008584 Not Cancer Driver No 36 0.1107692307692307 5 2 0.0061538461538461 0
MEA1-201 MEA1 Q16626 Male-enhanced antigen 1 chr6 GO:0008584 Not Cancer Driver No 14 0.0756756756756756 185 14 0.0756756756756756 0
MMP14-201 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0008584 Not Cancer Driver No 50 0.0859106529209622 120 6 0.0103092783505154 1
MSH2-201 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0008584 Census Yes 55 0.0588865096359743 37 1 0.0010706638115631 63
NASP-201 NASP P49321 Nuclear autoantigenic sperm protein chr1 GO:0008584 Not Cancer Driver No 61 0.0774111675126903 618 53 0.0672588832487309 0
NCOA1-202 NCOA1 Q15788 Nuclear receptor coactivator 1 chr2 GO:0008584 Census, Compendium Yes 135 0.0936849410131853 1217 107 0.0742539902845246 0
NCOA4-204 NCOA4 Q13772 Nuclear receptor coactivator 4 chr10 GO:0008584 Census Yes 60 0.0977198697068403 239 21 0.0342019543973941 0
NHLH2-201 NHLH2 Q02577 Helix-loop-helix protein 2 chr1 GO:0008584 Not Cancer Driver No 15 0.1111111111111111 83 7 0.0518518518518518 0
NKX3-1-201 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0008584 Not Cancer Driver No 26 0.1111111111111111 175 12 0.0512820512820512 0
NR0B1-202 NR0B1 P51843 Nuclear receptor subfamily 0 group B member 1 chrX GO:0008584 Not Cancer Driver No 74 0.1574468085106383 97 15 0.0319148936170212 16
NR5A1-202 NR5A1 Q13285 Steroidogenic factor 1 chr9 GO:0008584 Not Cancer Driver No 42 0.0911062906724512 135 18 0.0390455531453362 23
NUDT1-203 NUDT1 P36639 Oxidized purine nucleoside triphosphate hydrolase chr7 GO:0008584 Not Cancer Driver No 23 0.1474358974358974 17 4 0.0256410256410256 0
NUPR1-201 NUPR1 O60356 Nuclear protein 1 chr16 GO:0008584 Not Cancer Driver No 10 0.1219512195121951 82 10 0.1219512195121951 0
PATZ1-202 PATZ1 Q9HBE1 POZ-, AT hook-, and zinc finger-containing protein 1 chr22 GO:0008584 Census Yes 80 0.1164483260553129 301 34 0.049490538573508 0
PRDX4-202 PRDX4 Q13162 Peroxiredoxin-4 chrX GO:0008584 Not Cancer Driver No 31 0.1143911439114391 29 2 0.007380073800738 0
PRKACG-201 PRKACG P22612 cAMP-dependent protein kinase catalytic subunit gamma chr9 GO:0008584 Not Cancer Driver No 56 0.1595441595441595 23 6 0.017094017094017 1
PRPS1L1-201 PRPS1L1 P21108 Ribose-phosphate pyrophosphokinase 3 chr7 GO:0008584 Not Cancer Driver No 62 0.1949685534591195 0 0 0.0 0
RBMY1B-202 RBMY1B A6NDE4 RNA-binding motif protein, Y chromosome, family 1 member B chrY GO:0008584 Not Cancer Driver No 6 0.0120967741935483 459 6 0.0120967741935483 0
REN-201 REN P00797 Renin chr1 GO:0008584 Not Cancer Driver No 46 0.1133004926108374 10 0 0.0 3
RHOBTB3-201 RHOBTB3 O94955 Rho-related BTB domain-containing protein 3 chr5 GO:0008584 Not Cancer Driver No 46 0.0752864157119476 34 1 0.0016366612111292 0
RNF38-201 RNF38 Q9H0F5 E3 ubiquitin-protein ligase RNF38 chr9 GO:0008584 Not Cancer Driver No 47 0.0912621359223301 349 30 0.058252427184466 0
RRM1-201 RRM1 P23921 Ribonucleoside-diphosphate reductase large subunit chr11 GO:0008584 Not Cancer Driver No 54 0.0681818181818181 41 5 0.0063131313131313 0
RXFP2-201 RXFP2 Q8WXD0 Relaxin receptor 2 chr13 GO:0008584 Not Cancer Driver No 94 0.1246684350132626 0 0 0.0 1
SFRP1-201 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0008584 Not Cancer Driver No 31 0.0987261146496815 39 4 0.0127388535031847 0
SFRP2-201 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0008584 Not Cancer Driver No 37 0.1254237288135593 1 0 0.0 0
SIX4-201 SIX4 Q9UIU6 Homeobox protein SIX4 chr14 GO:0008584 Not Cancer Driver No 81 0.1037131882202304 462 48 0.0614596670934699 0
SOX15-201 SOX15 O60248 Protein SOX-15 chr17 GO:0008584 Not Cancer Driver No 13 0.055793991416309 228 13 0.055793991416309 0
SOX8-201 SOX8 P57073 Transcription factor SOX-8 chr16 GO:0008584 Not Cancer Driver No 38 0.085201793721973 403 35 0.0784753363228699 0
SOX9-201 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0008584 Compendium Yes 69 0.1355599214145383 497 66 0.1296660117878192 13
SRD5A1-201 SRD5A1 P18405 3-oxo-5-alpha-steroid 4-dehydrogenase 1 chr5 GO:0008584 Not Cancer Driver No 26 0.1003861003861003 0 0 0.0 0
SRD5A2-201 SRD5A2 P31213 3-oxo-5-alpha-steroid 4-dehydrogenase 2 chr2 GO:0008584 Not Cancer Driver No 0 0.0 0 0 0.0 20
TEX11-201 TEX11 Q8IYF3 Testis-expressed protein 11 chrX GO:0008584 Not Cancer Driver No 111 0.1180851063829787 30 3 0.0031914893617021 2
TEX19-201 TEX19 Q8NA77 Testis-expressed protein 19 chr17 GO:0008584 Not Cancer Driver No 22 0.1341463414634146 96 13 0.0792682926829268 0
TFAP2C-201 TFAP2C Q92754 Transcription factor AP-2 gamma chr20 GO:0008584 Not Cancer Driver No 57 0.1266666666666666 283 33 0.0733333333333333 0
TFPT-203 TFPT P0C1Z6 TCF3 fusion partner chr19 GO:0008584 Census Yes 32 0.1264822134387351 237 31 0.1225296442687747 0
TGFB2-202 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0008584 Not Cancer Driver No 44 0.1062801932367149 47 5 0.0120772946859903 4
TGFBR1-202 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0008584 Not Cancer Driver No 57 0.1133200795228628 23 3 0.0059642147117296 13
TLR3-201 TLR3 O15455 Toll-like receptor 3 chr4 GO:0008584 Not Cancer Driver No 89 0.0984513274336283 0 0 0.0 1
TLR9-201 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0008584 Not Cancer Driver No 107 0.1036821705426356 35 3 0.002906976744186 0
TNFSF10-201 TNFSF10 P50591 Tumor necrosis factor ligand superfamily member 10 chr3 GO:0008584 Not Cancer Driver No 38 0.1352313167259786 61 7 0.0249110320284697 0
UTF1-201 UTF1 Q5T230 Undifferentiated embryonic cell transcription factor 1 chr10 GO:0008584 Not Cancer Driver No 2 0.0058651026392961 318 2 0.0058651026392961 0
WNT2B-202 WNT2B Q93097 Protein Wnt-2b chr1 GO:0008584 Not Cancer Driver No 49 0.1253196930946291 27 1 0.0025575447570332 0
WNT4-201 WNT4 P56705 Protein Wnt-4 chr1 GO:0008584 Not Cancer Driver No 25 0.0712250712250712 39 2 0.0056980056980056 5
WNT5A-201 WNT5A P41221 Protein Wnt-5a chr3 GO:0008584 Not Cancer Driver No 42 0.1105263157894736 0 0 0.0 2
YBX3-201 YBX3 P16989 Y-box-binding protein 3 chr12 GO:0008584 Not Cancer Driver No 34 0.0913978494623656 362 33 0.0887096774193548 0
ZFP42-201 ZFP42 Q96MM3 Zinc finger protein 42 homolog chr4 GO:0008584 Not Cancer Driver No 111 0.3580645161290323 77 23 0.0741935483870967 0