Total number of protein in "GO:0008625" GO term: 40
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BAD-201 | BAD | Q92934 | Bcl2-associated agonist of cell death | chr11 | GO:0008625 | Not Cancer Driver | No | 10 | 0.0595238095238095 | 165 | 10 | 0.0595238095238095 | 0 |
BAG3-201 | BAG3 | O95817 | BAG family molecular chaperone regulator 3 | chr10 | GO:0008625 | Not Cancer Driver | No | 30 | 0.0521739130434782 | 572 | 30 | 0.0521739130434782 | 7 |
BAX-202 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0008625 | Census | Yes | 24 | 0.125 | 39 | 2 | 0.0104166666666666 | 0 |
BCL2-201 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:0008625 | Census, Compendium | Yes | 21 | 0.0878661087866108 | 73 | 5 | 0.0209205020920502 | 0 |
BEX3-203 | BEX3 | Q00994 | Protein BEX3 | chrX | GO:0008625 | Not Cancer Driver | No | 15 | 0.1351351351351351 | 98 | 13 | 0.1171171171171171 | 0 |
BID-211 | BID | P55957 | BH3-interacting domain death agonist | chr22 | GO:0008625 | Not Cancer Driver | No | 17 | 0.0871794871794871 | 75 | 5 | 0.0256410256410256 | 0 |
BLOC1S2-202 | BLOC1S2 | Q6QNY1 | Biogenesis of lysosome-related organelles complex 1 subunit 2 | chr10 | GO:0008625 | Not Cancer Driver | No | 9 | 0.0633802816901408 | 37 | 3 | 0.0211267605633802 | 0 |
CASP10-201 | CASP10 | Q92851 | Caspase-10 | chr2 | GO:0008625 | Not Cancer Driver | No | 37 | 0.0710172744721689 | 126 | 9 | 0.0172744721689059 | 3 |
CASP8-218 | CASP8 | Q14790 | Caspase-8 | chr2 | GO:0008625 | Census, Compendium | Yes | 116 | 0.2421711899791231 | 106 | 11 | 0.022964509394572 | 1 |
CASP8AP2-205 | CASP8AP2 | Q9UKL3 | CASP8-associated protein 2 | chr6 | GO:0008625 | Not Cancer Driver | No | 0 | 0.0 | 1508 | 0 | 0.0 | 0 |
CRADD-201 | CRADD | P78560 | Death domain-containing protein CRADD | chr12 | GO:0008625 | Not Cancer Driver | No | 30 | 0.1507537688442211 | 45 | 4 | 0.0201005025125628 | 1 |
DAB2IP-203 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:0008625 | Not Cancer Driver | No | 95 | 0.0798990748528175 | 682 | 49 | 0.04121110176619 | 0 |
DAPK1-202 | DAPK1 | P53355 | Death-associated protein kinase 1 | chr9 | GO:0008625 | Not Cancer Driver | No | 149 | 0.1041958041958042 | 116 | 12 | 0.0083916083916083 | 0 |
DAXX-202 | DAXX | Q9UER7 | Death domain-associated protein 6 | chr6 | GO:0008625 | Census, Compendium | Yes | 79 | 0.1067567567567567 | 549 | 57 | 0.077027027027027 | 0 |
DDX3X-244 | DDX3X | O00571 | ATP-dependent RNA helicase DDX3X | chrX | GO:0008625 | Census, Compendium | Yes | 91 | 0.1374622356495468 | 302 | 32 | 0.0483383685800604 | 18 |
DDX47-202 | DDX47 | Q9H0S4 | Probable ATP-dependent RNA helicase DDX47 | chr12 | GO:0008625 | Not Cancer Driver | No | 34 | 0.0747252747252747 | 98 | 6 | 0.0131868131868131 | 0 |
DEDD-202 | DEDD | O75618 | Death effector domain-containing protein | chr1 | GO:0008625 | Not Cancer Driver | No | 28 | 0.0880503144654088 | 90 | 2 | 0.0062893081761006 | 0 |
DEDD2-205 | DEDD2 | Q8WXF8 | DNA-binding death effector domain-containing protein 2 | chr19 | GO:0008625 | Not Cancer Driver | No | 27 | 0.0828220858895705 | 133 | 17 | 0.0521472392638036 | 0 |
DELE1-202 | DELE1 | Q14154 | DAP3-binding cell death enhancer 1 | chr5 | GO:0008625 | Not Cancer Driver | No | 45 | 0.087378640776699 | 197 | 18 | 0.0349514563106796 | 0 |
DIABLO-207 | DIABLO | Q9NR28 | Diablo IAP-binding mitochondrial protein | chr12 | GO:0008625 | Not Cancer Driver | No | 20 | 0.0836820083682008 | 54 | 2 | 0.00836820083682 | 1 |
FADD-201 | FADD | Q13158 | FAS-associated death domain protein | chr11 | GO:0008625 | Not Cancer Driver | No | 24 | 0.1153846153846153 | 45 | 9 | 0.0432692307692307 | 1 |
FASLG-202 | FASLG | P48023 | Tumor necrosis factor ligand superfamily member 6 | chr1 | GO:0008625 | Not Cancer Driver | No | 51 | 0.1814946619217081 | 94 | 15 | 0.0533807829181494 | 1 |
GABARAP-201 | GABARAP | O95166 | Gamma-aminobutyric acid receptor-associated protein | chr17 | GO:0008625 | Not Cancer Driver | No | 7 | 0.0598290598290598 | 12 | 0 | 0.0 | 0 |
HMGB2-201 | HMGB2 | P26583 | High mobility group protein B2 | chr4 | GO:0008625 | Not Cancer Driver | No | 26 | 0.124401913875598 | 207 | 26 | 0.124401913875598 | 0 |
ITPRIP-202 | ITPRIP | Q8IWB1 | Inositol 1,4,5-trisphosphate receptor-interacting protein | chr10 | GO:0008625 | Not Cancer Driver | No | 51 | 0.093235831809872 | 66 | 10 | 0.0182815356489945 | 0 |
MOAP1-201 | MOAP1 | Q96BY2 | Modulator of apoptosis 1 | chr14 | GO:0008625 | Not Cancer Driver | No | 37 | 0.1054131054131054 | 47 | 6 | 0.017094017094017 | 0 |
NF1-202 | NF1 | P21359 | Neurofibromin | chr17 | GO:0008625 | Census, Compendium | Yes | 285 | 0.1003874603733709 | 406 | 36 | 0.0126805213103205 | 75 |
NGF-201 | NGF | P01138 | Beta-nerve growth factor | chr1 | GO:0008625 | Not Cancer Driver | No | 56 | 0.2323651452282157 | 94 | 21 | 0.0871369294605809 | 1 |
PIDD1-201 | PIDD1 | Q9HB75 | p53-induced death domain-containing protein 1 | chr11 | GO:0008625 | Not Cancer Driver | No | 72 | 0.0791208791208791 | 140 | 9 | 0.0098901098901098 | 2 |
PIK3R1-211 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | GO:0008625 | Census, Compendium | Yes | 122 | 0.1685082872928177 | 271 | 50 | 0.0690607734806629 | 2 |
RAF1-201 | RAF1 | P04049 | RAF proto-oncogene serine/threonine-protein kinase | chr3 | GO:0008625 | Census, Compendium | Yes | 64 | 0.0987654320987654 | 169 | 30 | 0.0462962962962962 | 18 |
SKIL-201 | SKIL | P12757 | Ski-like protein | chr3 | GO:0008625 | Not Cancer Driver | No | 55 | 0.0804093567251462 | 359 | 24 | 0.0350877192982456 | 0 |
SORT1-201 | SORT1 | Q99523 | Sortilin | chr1 | GO:0008625 | Not Cancer Driver | No | 54 | 0.0649819494584837 | 110 | 0 | 0.0 | 0 |
STK3-201 | STK3 | Q13188 | Serine/threonine-protein kinase 3 | chr8 | GO:0008625 | Not Cancer Driver | No | 48 | 0.0977596741344195 | 241 | 22 | 0.0448065173116089 | 0 |
STK4-202 | STK4 | Q13043 | Serine/threonine-protein kinase 4 | chr20 | GO:0008625 | Not Cancer Driver | No | 49 | 0.1006160164271047 | 233 | 20 | 0.0410677618069815 | 0 |
TNF-208 | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0008625 | Not Cancer Driver | No | 22 | 0.0944206008583691 | 45 | 2 | 0.0085836909871244 | 0 |
TNFRSF10A-201 | TNFRSF10A | O00220 | Tumor necrosis factor receptor superfamily member 10A | chr8 | GO:0008625 | Not Cancer Driver | No | 39 | 0.0833333333333333 | 175 | 14 | 0.0299145299145299 | 0 |
TNFRSF10B-201 | TNFRSF10B | O14763 | Tumor necrosis factor receptor superfamily member 10B | chr8 | GO:0008625 | Not Cancer Driver | No | 36 | 0.0818181818181818 | 192 | 15 | 0.034090909090909 | 0 |
TNFRSF1A-201 | TNFRSF1A | P19438 | Tumor necrosis factor receptor superfamily member 1A | chr12 | GO:0008625 | Not Cancer Driver | No | 38 | 0.0835164835164835 | 111 | 14 | 0.0307692307692307 | 9 |
TRADD-201 | TRADD | Q15628 | Tumor necrosis factor receptor type 1-associated DEATH domain protein | chr16 | GO:0008625 | Not Cancer Driver | No | 18 | 0.0576923076923076 | 74 | 4 | 0.0128205128205128 | 0 |