Total number of protein in "GO:0008630" GO term: 47
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1-201 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0008630 | Census, Compendium | Yes | 106 | 0.0938053097345132 | 609 | 53 | 0.0469026548672566 | 2 |
| ATM-229 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0008630 | Census, Compendium | Yes | 358 | 0.1171465968586387 | 226 | 29 | 0.0094895287958115 | 41 |
| BAD-201 | BAD | Q92934 | Bcl2-associated agonist of cell death | chr11 | GO:0008630 | Not Cancer Driver | No | 10 | 0.0595238095238095 | 165 | 10 | 0.0595238095238095 | 0 |
| BAK1-201 | BAK1 | Q16611 | Bcl-2 homologous antagonist/killer | chr6 | GO:0008630 | Not Cancer Driver | No | 25 | 0.1184834123222748 | 58 | 5 | 0.0236966824644549 | 0 |
| BAX-202 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0008630 | Census | Yes | 24 | 0.125 | 39 | 2 | 0.0104166666666666 | 0 |
| BCL2-201 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:0008630 | Census, Compendium | Yes | 21 | 0.0878661087866108 | 73 | 5 | 0.0209205020920502 | 0 |
| BCL2A1-201 | BCL2A1 | Q16548 | Bcl-2-related protein A1 | chr15 | GO:0008630 | Not Cancer Driver | No | 18 | 0.1028571428571428 | 0 | 0 | 0.0 | 0 |
| BCL2L1-201 | BCL2L1 | Q07817 | Bcl-2-like protein 1 | chr20 | GO:0008630 | Not Cancer Driver | No | 22 | 0.0944206008583691 | 55 | 2 | 0.0085836909871244 | 0 |
| BCL2L10-201 | BCL2L10 | Q9HD36 | Bcl-2-like protein 10 | chr15 | GO:0008630 | Not Cancer Driver | No | 6 | 0.0294117647058823 | 35 | 0 | 0.0 | 0 |
| BCL2L11-204 | BCL2L11 | O43521 | Bcl-2-like protein 11 | chr2 | GO:0008630 | Not Cancer Driver | No | 37 | 0.1868686868686868 | 131 | 16 | 0.0808080808080808 | 0 |
| BCL2L2-201 | BCL2L2 | Q92843 | Bcl-2-like protein 2 | chr14 | GO:0008630 | Not Cancer Driver | No | 14 | 0.0725388601036269 | 34 | 2 | 0.0103626943005181 | 0 |
| BOK-201 | BOK | Q9UMX3 | Bcl-2-related ovarian killer protein | chr2 | GO:0008630 | Not Cancer Driver | No | 5 | 0.0235849056603773 | 0 | 0 | 0.0 | 0 |
| BRCA1-203 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | GO:0008630 | Census, Compendium | Yes | 167 | 0.0896403650026838 | 1466 | 127 | 0.0681696188942565 | 34 |
| CASP2-201 | CASP2 | P42575 | Caspase-2 | chr7 | GO:0008630 | Not Cancer Driver | No | 49 | 0.1084070796460177 | 42 | 11 | 0.0243362831858407 | 0 |
| CASP9-201 | CASP9 | P55211 | Caspase-9 | chr1 | GO:0008630 | Census | Yes | 26 | 0.0625 | 71 | 7 | 0.016826923076923 | 0 |
| CHEK2-206 | CHEK2 | O96017 | Serine/threonine-protein kinase Chk2 | chr22 | GO:0008630 | Census, Compendium | Yes | 72 | 0.1325966850828729 | 157 | 19 | 0.0349907918968692 | 11 |
| CIDEB-203 | CIDEB | Q9UHD4 | Lipid transferase CIDEB | chr14 | GO:0008630 | Not Cancer Driver | No | 17 | 0.0776255707762557 | 23 | 1 | 0.0045662100456621 | 0 |
| CRIP1-202 | CRIP1 | P50238 | Cysteine-rich protein 1 | chr14 | GO:0008630 | Not Cancer Driver | No | 2 | 0.0259740259740259 | 8 | 0 | 0.0 | 0 |
| E2F1-201 | E2F1 | Q01094 | Transcription factor E2F1 | chr20 | GO:0008630 | Not Cancer Driver | No | 39 | 0.0892448512585812 | 273 | 17 | 0.0389016018306636 | 0 |
| ENST00000477724 | CRIP1 | P50238 | Cysteine-rich protein 1 | chr14 | GO:0008630 | Not Cancer Driver | No | 2 | 0.0259740259740259 | 9 | 0 | 0.0 | 0 |
| EPHA2-201 | EPHA2 | P29317 | Ephrin type-A receptor 2 | chr1 | GO:0008630 | Compendium | Yes | 147 | 0.1506147540983606 | 188 | 33 | 0.033811475409836 | 3 |
| ERCC6-201 | ERCC6 | Q03468 | DNA excision repair protein ERCC-6 | chr10 | GO:0008630 | Not Cancer Driver | No | 142 | 0.0951105157401205 | 837 | 82 | 0.0549229738780977 | 9 |
| FNIP2-201 | FNIP2 | Q9P278 | Folliculin-interacting protein 2 | chr4 | GO:0008630 | Not Cancer Driver | No | 87 | 0.078096947935368 | 556 | 53 | 0.0475763016157989 | 0 |
| HIC1-201 | HIC1 | Q14526 | Hypermethylated in cancer 1 protein | chr17 | GO:0008630 | Not Cancer Driver | No | 22 | 0.0300136425648021 | 362 | 5 | 0.0068212824010914 | 0 |
| HTRA2-201 | HTRA2 | O43464 | Serine protease HTRA2, mitochondrial | chr2 | GO:0008630 | Compendium | Yes | 33 | 0.0720524017467248 | 127 | 7 | 0.0152838427947598 | 2 |
| IER3-201 | IER3 | P46695 | Radiation-inducible immediate-early gene IEX-1 | chr6 | GO:0008630 | Not Cancer Driver | No | 4 | 0.0256410256410256 | 106 | 3 | 0.0192307692307692 | 0 |
| IKBKE-203 | IKBKE | Q14164 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon | chr1 | GO:0008630 | Not Cancer Driver | No | 90 | 0.1256983240223463 | 76 | 10 | 0.0139664804469273 | 0 |
| MAEL-202 | MAEL | Q96JY0 | Protein maelstrom homolog | chr1 | GO:0008630 | Not Cancer Driver | No | 95 | 0.2188940092165898 | 116 | 26 | 0.0599078341013824 | 0 |
| MCL1-202 | MCL1 | Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | chr1 | GO:0008630 | Not Cancer Driver | No | 27 | 0.0771428571428571 | 204 | 19 | 0.0542857142857142 | 0 |
| MLH1-201 | MLH1 | P40692 | DNA mismatch repair protein Mlh1 | chr3 | GO:0008630 | Census | Yes | 65 | 0.0859788359788359 | 208 | 13 | 0.0171957671957671 | 77 |
| MOAP1-201 | MOAP1 | Q96BY2 | Modulator of apoptosis 1 | chr14 | GO:0008630 | Not Cancer Driver | No | 37 | 0.1054131054131054 | 47 | 6 | 0.017094017094017 | 0 |
| MSH6-201 | MSH6 | P52701 | DNA mismatch repair protein Msh6 | chr2 | GO:0008630 | Census | Yes | 92 | 0.0676470588235294 | 389 | 26 | 0.0191176470588235 | 6 |
| NFATC4-201 | NFATC4 | Q14934 | Nuclear factor of activated T-cells, cytoplasmic 4 | chr14 | GO:0008630 | Not Cancer Driver | No | 122 | 0.1352549889135255 | 685 | 92 | 0.1019955654101995 | 0 |
| PIK3R1-211 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | GO:0008630 | Census, Compendium | Yes | 122 | 0.1685082872928177 | 271 | 50 | 0.0690607734806629 | 2 |
| PML-201 | PML | P29590 | Protein PML | chr15 | GO:0008630 | Census, Compendium | Yes | 87 | 0.0986394557823129 | 312 | 28 | 0.0317460317460317 | 0 |
| POLB-201 | POLB | P06746 | DNA polymerase beta | chr8 | GO:0008630 | Not Cancer Driver | No | 32 | 0.0955223880597015 | 87 | 8 | 0.0238805970149253 | 0 |
| PRKDC-201 | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | GO:0008630 | Not Cancer Driver | No | 385 | 0.0932655038759689 | 421 | 43 | 0.0104166666666666 | 2 |
| RAD9A-201 | RAD9A | Q99638 | Cell cycle checkpoint control protein RAD9A | chr11 | GO:0008630 | Not Cancer Driver | No | 32 | 0.0818414322250639 | 136 | 7 | 0.0179028132992327 | 0 |
| SFN-201 | SFN | P31947 | 14-3-3 protein sigma | chr1 | GO:0008630 | Not Cancer Driver | No | 16 | 0.064516129032258 | 75 | 3 | 0.0120967741935483 | 0 |
| SKIL-201 | SKIL | P12757 | Ski-like protein | chr3 | GO:0008630 | Not Cancer Driver | No | 55 | 0.0804093567251462 | 359 | 24 | 0.0350877192982456 | 0 |
| SOD2-210 | SOD2 | P04179 | Superoxide dismutase [Mn], mitochondrial | chr6 | GO:0008630 | Not Cancer Driver | No | 21 | 0.0945945945945946 | 25 | 3 | 0.0135135135135135 | 0 |
| TNF-208 | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0008630 | Not Cancer Driver | No | 22 | 0.0944206008583691 | 45 | 2 | 0.0085836909871244 | 0 |
| TNFRSF1A-201 | TNFRSF1A | P19438 | Tumor necrosis factor receptor superfamily member 1A | chr12 | GO:0008630 | Not Cancer Driver | No | 38 | 0.0835164835164835 | 111 | 14 | 0.0307692307692307 | 9 |
| TNFRSF1B-201 | TNFRSF1B | P20333 | Tumor necrosis factor receptor superfamily member 1B | chr1 | GO:0008630 | Not Cancer Driver | No | 40 | 0.0867678958785249 | 231 | 21 | 0.0455531453362256 | 0 |
| TOPORS-201 | TOPORS | Q9NS56 | E3 ubiquitin-protein ligase Topors | chr9 | GO:0008630 | Not Cancer Driver | No | 62 | 0.0593301435406698 | 796 | 38 | 0.0363636363636363 | 0 |
| TP73-208 | TP73 | O15350 | Tumor protein p73 | chr1 | GO:0008630 | Not Cancer Driver | No | 67 | 0.1053459119496855 | 446 | 45 | 0.070754716981132 | 0 |
| USP47-203 | USP47 | Q96K76 | Ubiquitin carboxyl-terminal hydrolase 47 | chr11 | GO:0008630 | Not Cancer Driver | No | 86 | 0.0625454545454545 | 426 | 24 | 0.0174545454545454 | 0 |