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Total number of protein in "GO:0009653" GO term:  122

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ARMC5-201 ARMC5 Q96C12 Armadillo repeat-containing protein 5 chr16 GO:0009653 Not Cancer Driver No 96 0.1026737967914438 268 22 0.0235294117647058 14
ATOH8-201 ATOH8 Q96SQ7 Transcription factor ATOH8 chr2 GO:0009653 Not Cancer Driver No 24 0.0747663551401869 257 18 0.0560747663551401 0
BICD1-210 BICD1 Q96G01 Protein bicaudal D homolog 1 chr12 GO:0009653 Not Cancer Driver No 105 0.1076923076923077 661 70 0.0717948717948717 0
CASR-205 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0009653 Not Cancer Driver No 234 0.2170686456400742 189 46 0.0426716141001855 100
CHUK-201 CHUK O15111 Inhibitor of nuclear factor kappa-B kinase subunit alpha chr10 GO:0009653 Not Cancer Driver No 49 0.0657718120805369 116 7 0.0093959731543624 0
CLTCL1-202 CLTCL1 P53675 Clathrin heavy chain 2 chr22 GO:0009653 Census, Compendium Yes 160 0.0975609756097561 10 1 0.0006097560975609 0
CPM-211 CPM P14384 Carboxypeptidase M chr12 GO:0009653 Not Cancer Driver No 48 0.1083521444695259 16 1 0.0022573363431151 0
CST6-201 CST6 Q15828 Cystatin-M chr11 GO:0009653 Not Cancer Driver No 16 0.1073825503355704 29 1 0.0067114093959731 0
DEAF1-201 DEAF1 O75398 Deformed epidermal autoregulatory factor 1 homolog chr11 GO:0009653 Not Cancer Driver No 60 0.1061946902654867 371 40 0.0707964601769911 4
DKK3-217 DKK3 Q9UBP4 Dickkopf-related protein 3 chr11 GO:0009653 Not Cancer Driver No 35 0.1 162 14 0.04 0
DKKL1-201 DKKL1 Q9UK85 Dickkopf-like protein 1 chr19 GO:0009653 Not Cancer Driver No 36 0.1487603305785124 138 24 0.0991735537190082 0
EFNB2-202 EFNB2 P52799 Ephrin-B2 chr13 GO:0009653 Not Cancer Driver No 37 0.1111111111111111 99 11 0.033033033033033 0
EN1-201 EN1 Q05925 Homeobox protein engrailed-1 chr2 GO:0009653 Not Cancer Driver No 29 0.0739795918367346 358 20 0.0510204081632653 0
EREG-201 EREG O14944 Proepiregulin chr4 GO:0009653 Not Cancer Driver No 19 0.1124260355029585 10 2 0.0118343195266272 0
ERVW-1-202 ERVW-1 Q9UQF0 Syncytin-1 chr7 GO:0009653 Not Cancer Driver No 45 0.0836431226765799 91 9 0.0167286245353159 0
EYA1-202 EYA1 Q99502 Eyes absent homolog 1 chr8 GO:0009653 Not Cancer Driver No 128 0.2162162162162162 342 75 0.1266891891891892 15
EYA3-203 EYA3 Q99504 Eyes absent homolog 3 chr1 GO:0009653 Not Cancer Driver No 44 0.0767888307155322 310 30 0.0523560209424083 0
EYA4-202 EYA4 O95677 Eyes absent homolog 4 chr6 GO:0009653 Not Cancer Driver No 142 0.2222222222222222 339 81 0.1267605633802817 2
EZH1-202 EZH1 Q92800 Histone-lysine N-methyltransferase EZH1 chr17 GO:0009653 Not Cancer Driver No 60 0.0803212851405622 213 18 0.0240963855421686 0
F2R-201 F2R P25116 Proteinase-activated receptor 1 chr5 GO:0009653 Not Cancer Driver No 55 0.1294117647058823 19 2 0.0047058823529411 0
FAT1-201 FAT1 Q14517 Protocadherin Fat 1 chr4 GO:0009653 Census, Compendium Yes 432 0.094158674803836 1060 85 0.0185265911072362 0
FBN1-201 FBN1 P35555 Fibrillin-1 chr15 GO:0009653 Not Cancer Driver No 358 0.124695228143504 110 13 0.0045280390107976 340
FBN2-201 FBN2 P35556 Fibrillin-2 chr5 GO:0009653 Compendium Yes 476 0.1634615384615384 137 21 0.0072115384615384 27
FBN3-205 FBN3 Q75N90 Fibrillin-3 chr19 GO:0009653 Not Cancer Driver No 367 0.1306514773940904 104 22 0.0078319686721253 0
FGF1-201 FGF1 P05230 Fibroblast growth factor 1 chr5 GO:0009653 Not Cancer Driver No 21 0.1354838709677419 29 2 0.0129032258064516 0
FGF18-201 FGF18 O76093 Fibroblast growth factor 18 chr5 GO:0009653 Not Cancer Driver No 29 0.1400966183574879 57 8 0.038647342995169 0
FGF3-201 FGF3 P11487 Fibroblast growth factor 3 chr11 GO:0009653 Not Cancer Driver No 31 0.1297071129707113 105 19 0.0794979079497908 2
FGF8-202 FGF8 P55075 Fibroblast growth factor 8 chr10 GO:0009653 Not Cancer Driver No 27 0.1158798283261802 79 8 0.0343347639484978 6
FOXA1-201 FOXA1 P55317 Hepatocyte nuclear factor 3-alpha chr14 GO:0009653 Census, Compendium Yes 85 0.1800847457627118 295 44 0.0932203389830508 0
FOXA2-201 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 GO:0009653 Compendium Yes 60 0.1312910284463894 260 29 0.0634573304157549 0
FOXA3-201 FOXA3 P55318 Hepatocyte nuclear factor 3-gamma chr19 GO:0009653 Not Cancer Driver No 50 0.1428571428571428 233 30 0.0857142857142857 0
FOXB1-201 FOXB1 Q99853 Forkhead box protein B1 chr15 GO:0009653 Not Cancer Driver No 25 0.0769230769230769 114 4 0.0123076923076923 0
FOXB2-201 FOXB2 Q5VYV0 Forkhead box protein B2 chr9 GO:0009653 Not Cancer Driver No 49 0.1134259259259259 264 31 0.0717592592592592 0
FOXC1-201 FOXC1 Q12948 Forkhead box protein C1 chr6 GO:0009653 Not Cancer Driver No 23 0.0415913200723327 409 14 0.0253164556962025 25
FOXC2-201 FOXC2 Q99958 Forkhead box protein C2 chr16 GO:0009653 Not Cancer Driver No 52 0.1037924151696606 370 31 0.06187624750499 1
FOXD1-202 FOXD1 Q16676 Forkhead box protein D1 chr5 GO:0009653 Not Cancer Driver No 7 0.0150537634408602 262 5 0.010752688172043 0
FOXD2-201 FOXD2 O60548 Forkhead box protein D2 chr1 GO:0009653 Not Cancer Driver No 15 0.0303030303030303 330 6 0.0121212121212121 0
FOXD3-201 FOXD3 Q9UJU5 Forkhead box protein D3 chr1 GO:0009653 Not Cancer Driver No 22 0.0460251046025104 263 12 0.0251046025104602 0
FOXD4-201 FOXD4 Q12950 Forkhead box protein D4 chr9 GO:0009653 Not Cancer Driver No 54 0.123006833712984 336 44 0.1002277904328018 0
FOXD4L1-201 FOXD4L1 Q9NU39 Forkhead box protein D4-like 1 chr2 GO:0009653 Compendium Yes 37 0.0906862745098039 296 25 0.0612745098039215 0
FOXD4L3-201 FOXD4L3 Q6VB84 Forkhead box protein D4-like 3 chr9 GO:0009653 Not Cancer Driver No 21 0.0503597122302158 212 9 0.0215827338129496 0
FOXD4L4-201 FOXD4L4 Q8WXT5 Forkhead box protein D4-like 4 chr9 GO:0009653 Not Cancer Driver No 0 0.0 210 0 0.0 0
FOXD4L5-201 FOXD4L5 Q5VV16 Forkhead box protein D4-like 5 chr9 GO:0009653 Not Cancer Driver No 52 0.125 202 30 0.0721153846153846 0
FOXD4L6-201 FOXD4L6 Q3SYB3 Forkhead box protein D4-like 6 chr9 GO:0009653 Not Cancer Driver No 6 0.014388489208633 217 2 0.0047961630695443 0
FOXE1-201 FOXE1 O00358 Forkhead box protein E1 chr9 GO:0009653 Not Cancer Driver No 30 0.0804289544235924 134 3 0.0080428954423592 4
FOXE3-201 FOXE3 Q13461 Forkhead box protein E3 chr1 GO:0009653 Not Cancer Driver No 11 0.0344827586206896 188 3 0.0094043887147335 6
FOXI1-201 FOXI1 Q12951 Forkhead box protein I1 chr5 GO:0009653 Not Cancer Driver No 74 0.1957671957671957 254 56 0.1481481481481481 0
FOXI2-201 FOXI2 Q6ZQN5 Forkhead box protein I2 chr10 GO:0009653 Not Cancer Driver No 28 0.0880503144654088 166 20 0.0628930817610062 0
FOXI3-201 FOXI3 A8MTJ6 Forkhead box protein I3 chr2 GO:0009653 Not Cancer Driver No 0 0.0 286 0 0.0 0
FOXL1-201 FOXL1 Q12952 Forkhead box protein L1 chr16 GO:0009653 Not Cancer Driver No 41 0.1188405797101449 213 18 0.0521739130434782 0
FOXL2-201 FOXL2 P58012 Forkhead box protein L2 chr3 GO:0009653 Census, Compendium Yes 33 0.0877659574468085 258 16 0.0425531914893617 22
FOXL3-201 FOXL3 A0A1W2PRP0 Forkhead box protein L3 chr7 GO:0009653 Not Cancer Driver No 0 0.0 141 0 0.0 0
FOXQ1-201 FOXQ1 Q9C009 Forkhead box protein Q1 chr6 GO:0009653 Not Cancer Driver No 22 0.0545905707196029 248 5 0.0124069478908188 0
FOXS1-201 FOXS1 O43638 Forkhead box protein S1 chr20 GO:0009653 Not Cancer Driver No 51 0.1545454545454545 229 34 0.103030303030303 0
FRAS1-206 FRAS1 Q86XX4 Extracellular matrix organizing protein FRAS1 chr4 GO:0009653 Not Cancer Driver No 475 0.1183948155533399 774 99 0.0246759720837487 0
FREM1-202 FREM1 Q5H8C1 FRAS1-related extracellular matrix protein 1 chr9 GO:0009653 Not Cancer Driver No 326 0.1496099128040385 303 37 0.0169802661771454 6
FREM2-201 FREM2 Q5SZK8 FRAS1-related extracellular matrix protein 2 chr13 GO:0009653 Not Cancer Driver No 435 0.1372672767434521 787 121 0.0381823919217418 3
FREM3-201 FREM3 P0C091 FRAS1-related extracellular matrix protein 3 chr4 GO:0009653 Not Cancer Driver No 0 0.0 532 0 0.0 0
FSCN2-202 FSCN2 O14926 Fascin-2 chr17 GO:0009653 Not Cancer Driver No 29 0.0589430894308943 48 3 0.0060975609756097 0
GATA3-201 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0009653 Census, Compendium Yes 99 0.2234762979683973 368 79 0.1783295711060948 2
GCM1-201 GCM1 Q9NP62 Chorion-specific transcription factor GCMa chr6 GO:0009653 Not Cancer Driver No 58 0.1330275229357798 197 31 0.0711009174311926 0
GPC3-201 GPC3 P51654 Glypican-3 chrX GO:0009653 Census Yes 55 0.0948275862068965 87 7 0.0120689655172413 1
GSC2-201 GSC2 O15499 Homeobox protein goosecoid-2 chr22 GO:0009653 Not Cancer Driver No 7 0.0341463414634146 116 5 0.024390243902439 0
HIRA-201 HIRA P54198 Protein HIRA chr22 GO:0009653 Not Cancer Driver No 104 0.1022615535889872 289 30 0.0294985250737463 0
HOXA1-202 HOXA1 P49639 Homeobox protein Hox-A1 chr7 GO:0009653 Not Cancer Driver No 62 0.1850746268656716 261 44 0.1313432835820895 0
HOXA11-201 HOXA11 P31270 Homeobox protein Hox-A11 chr7 GO:0009653 Census, Compendium Yes 25 0.0798722044728434 205 16 0.0511182108626198 0
HOXA4-201 HOXA4 Q00056 Homeobox protein Hox-A4 chr7 GO:0009653 Not Cancer Driver No 24 0.075 258 12 0.0375 0
HOXB5-201 HOXB5 P09067 Homeobox protein Hox-B5 chr17 GO:0009653 Not Cancer Driver No 34 0.1263940520446096 203 26 0.0966542750929368 0
HOXC13-201 HOXC13 P31276 Homeobox protein Hox-C13 chr12 GO:0009653 Census, Compendium Yes 42 0.1272727272727272 203 30 0.0909090909090909 0
IER3-201 IER3 P46695 Radiation-inducible immediate-early gene IEX-1 chr6 GO:0009653 Not Cancer Driver No 4 0.0256410256410256 106 3 0.0192307692307692 0
IGF2BP2-202 IGF2BP2 Q9Y6M1 Insulin-like growth factor 2 mRNA-binding protein 2 chr3 GO:0009653 Census Yes 51 0.0851419031719532 237 23 0.0383973288814691 0
IGF2BP3-201 IGF2BP3 O00425 Insulin-like growth factor 2 mRNA-binding protein 3 chr7 GO:0009653 Not Cancer Driver No 61 0.1053540587219343 267 31 0.0535405872193437 0
KRT18-201 KRT18 P05783 Keratin, type I cytoskeletal 18 chr12 GO:0009653 Not Cancer Driver No 46 0.1069767441860465 179 17 0.0395348837209302 4
KRT35-201 KRT35 Q92764 Keratin, type I cuticular Ha5 chr17 GO:0009653 Not Cancer Driver No 66 0.145054945054945 66 6 0.0131868131868131 0
LBX1-201 LBX1 P52954 Transcription factor LBX1 chr10 GO:0009653 Not Cancer Driver No 20 0.0711743772241993 181 14 0.0498220640569395 0
LHX1-201 LHX1 P48742 LIM/homeobox protein Lhx1 chr17 GO:0009653 Not Cancer Driver No 37 0.0911330049261083 268 23 0.0566502463054187 0
LIG1-201 LIG1 P18858 DNA ligase 1 chr19 GO:0009653 Not Cancer Driver No 99 0.1077257889009793 400 50 0.0544069640914037 3
LST1-217 LST1 O00453 Leukocyte-specific transcript 1 protein chr6 GO:0009653 Not Cancer Driver No 3 0.0309278350515463 36 2 0.0206185567010309 0
LYVE1-201 LYVE1 Q9Y5Y7 Lymphatic vessel endothelial hyaluronic acid receptor 1 chr11 GO:0009653 Not Cancer Driver No 23 0.0714285714285714 77 9 0.0279503105590062 0
MAB21L1-201 MAB21L1 Q13394 Putative nucleotidyltransferase MAB21L1 chr13 GO:0009653 Not Cancer Driver No 75 0.2089136490250696 0 0 0.0 0
MCAM-201 MCAM P43121 Cell surface glycoprotein MUC18 chr11 GO:0009653 Not Cancer Driver No 63 0.0975232198142414 310 29 0.044891640866873 0
MLXIPL-201 MLXIPL Q9NP71 Carbohydrate-responsive element-binding protein chr7 GO:0009653 Not Cancer Driver No 86 0.1009389671361502 557 54 0.0633802816901408 0
MPZL2-201 MPZL2 O60487 Myelin protein zero-like protein 2 chr11 GO:0009653 Not Cancer Driver No 22 0.1023255813953488 0 0 0.0 0
MRPL40-201 MRPL40 Q9NQ50 Large ribosomal subunit protein mL40 chr22 GO:0009653 Not Cancer Driver No 17 0.0825242718446602 105 10 0.0485436893203883 0
NEDD8-201 NEDD8 Q15843 NEDD8 chr14 GO:0009653 Not Cancer Driver No 9 0.1111111111111111 36 4 0.0493827160493827 0
NFE2L1-203 NFE2L1 Q14494 Endoplasmic reticulum membrane sensor NFE2L1 chr17 GO:0009653 Not Cancer Driver No 49 0.0634715025906735 512 21 0.0272020725388601 0
ONECUT1-201 ONECUT1 Q9UBC0 Hepatocyte nuclear factor 6 chr15 GO:0009653 Not Cancer Driver No 57 0.1225806451612903 409 47 0.1010752688172043 0
PAX7-203 PAX7 P23759 Paired box protein Pax-7 chr1 GO:0009653 Census Yes 78 0.1544554455445544 396 61 0.1207920792079207 1
PAX8-205 PAX8 Q06710 Paired box protein Pax-8 chr2 GO:0009653 Census Yes 60 0.1333333333333333 291 34 0.0755555555555555 4
PHLDA3-202 PHLDA3 Q9Y5J5 Pleckstrin homology-like domain family A member 3 chr1 GO:0009653 Not Cancer Driver No 14 0.1102362204724409 0 0 0.0 0
PITX1-201 PITX1 P78337 Pituitary homeobox 1 chr5 GO:0009653 Not Cancer Driver No 24 0.0764331210191082 193 11 0.0350318471337579 1
PITX2-201 PITX2 Q99697 Pituitary homeobox 2 chr4 GO:0009653 Not Cancer Driver No 68 0.2145110410094637 186 41 0.1293375394321766 12
PITX3-201 PITX3 O75364 Pituitary homeobox 3 chr10 GO:0009653 Not Cancer Driver No 21 0.0695364238410596 155 11 0.0364238410596026 1
PKD1-201 PKD1 P98161 Polycystin-1 chr16 GO:0009653 Not Cancer Driver No 299 0.0694864048338368 695 50 0.0116198001394376 91
POU5F1-201 POU5F1 Q01860 POU domain, class 5, transcription factor 1 chr6 GO:0009653 Census Yes 27 0.075 186 8 0.0222222222222222 0
PTBP3-204 PTBP3 O95758 Polypyrimidine tract-binding protein 3 chr9 GO:0009653 Not Cancer Driver No 39 0.0706521739130434 114 8 0.0144927536231884 0
RAC1-201 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0009653 Census, Compendium Yes 61 0.3177083333333333 2 0 0.0 6
RCAN3-202 RCAN3 Q9UKA8 Calcipressin-3 chr1 GO:0009653 Not Cancer Driver No 24 0.0995850622406639 122 13 0.0539419087136929 0
S1PR3-202 S1PR3 Q99500 Sphingosine 1-phosphate receptor 3 chr9 GO:0009653 Not Cancer Driver No 53 0.1402116402116402 29 4 0.0105820105820105 0
SCML2-201 SCML2 Q9UQR0 Sex comb on midleg-like protein 2 chrX GO:0009653 Not Cancer Driver No 84 0.12 411 50 0.0714285714285714 0
SFRP5-201 SFRP5 Q5T4F7 Secreted frizzled-related protein 5 chr10 GO:0009653 Not Cancer Driver No 16 0.0504731861198738 7 2 0.0063091482649842 0
SIAH1-203 SIAH1 Q8IUQ4 E3 ubiquitin-protein ligase SIAH1 chr16 GO:0009653 Not Cancer Driver No 22 0.0780141843971631 28 2 0.0070921985815602 5
SIX2-201 SIX2 Q9NPC8 Homeobox protein SIX2 chr2 GO:0009653 Census Yes 38 0.1305841924398625 151 16 0.0549828178694158 0
SIX4-201 SIX4 Q9UIU6 Homeobox protein SIX4 chr14 GO:0009653 Not Cancer Driver No 81 0.1037131882202304 462 48 0.0614596670934699 0
SMAD1-201 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 GO:0009653 Not Cancer Driver No 39 0.0838709677419354 162 19 0.0408602150537634 0
SMAD2-201 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:0009653 Census, Compendium Yes 58 0.1241970021413276 137 11 0.0235546038543897 3
SMAD3-201 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0009653 Census, Compendium Yes 80 0.188235294117647 113 15 0.0352941176470588 5
SMAD4-201 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0009653 Census, Compendium Yes 172 0.3115942028985507 195 16 0.0289855072463768 6
SMAD5-211 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 GO:0009653 Not Cancer Driver No 25 0.053763440860215 172 6 0.0129032258064516 0
SMAD6-201 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 GO:0009653 Not Cancer Driver No 29 0.0584677419354838 249 4 0.0080645161290322 7
SMAD7-201 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0009653 Not Cancer Driver No 38 0.0892018779342723 140 0 0.0 0
SMAD9-202 SMAD9 O15198 Mothers against decapentaplegic homolog 9 chr13 GO:0009653 Not Cancer Driver No 64 0.1370449678800856 132 14 0.0299785867237687 1
SOX10-202 SOX10 P56693 Transcription factor SOX-10 chr22 GO:0009653 Not Cancer Driver No 58 0.1244635193133047 424 55 0.1180257510729613 12
SOX13-203 SOX13 Q9UN79 Transcription factor SOX-13 chr1 GO:0009653 Not Cancer Driver No 67 0.107717041800643 566 59 0.0948553054662379 0
TBX10-201 TBX10 O75333 T-box transcription factor TBX10 chr11 GO:0009653 Not Cancer Driver No 41 0.1064935064935064 152 13 0.0337662337662337 0
TBX19-201 TBX19 O60806 T-box transcription factor TBX19 chr1 GO:0009653 Not Cancer Driver No 52 0.1160714285714285 233 21 0.046875 1
TBX6-202 TBX6 O95947 T-box transcription factor TBX6 chr16 GO:0009653 Not Cancer Driver No 34 0.0779816513761468 253 17 0.0389908256880734 0
TH-206 TH P07101 Tyrosine 3-monooxygenase chr11 GO:0009653 Not Cancer Driver No 48 0.0909090909090909 151 17 0.0321969696969696 38
TPD52-202 TPD52 P55327 Tumor protein D52 chr8 GO:0009653 Not Cancer Driver No 18 0.0803571428571428 176 14 0.0625 0
TRIM13-202 TRIM13 O60858 E3 ubiquitin-protein ligase TRIM13 chr13 GO:0009653 Not Cancer Driver No 41 0.1007371007371007 1 0 0.0 0
TSHB-201 TSHB P01222 Thyrotropin subunit beta chr1 GO:0009653 Not Cancer Driver No 25 0.181159420289855 0 0 0.0 1
ZNF141-201 ZNF141 Q15928 Zinc finger protein 141 chr4 GO:0009653 Not Cancer Driver No 37 0.0780590717299578 64 11 0.0232067510548523 1