Total number of protein in "GO:0009952" GO term: 91
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACVR2A-201 | ACVR2A | P27037 | Activin receptor type-2A | chr2 | GO:0009952 | Census, Compendium | Yes | 64 | 0.124756335282651 | 56 | 4 | 0.0077972709551656 | 0 |
| ACVR2B-201 | ACVR2B | Q13705 | Activin receptor type-2B | chr3 | GO:0009952 | Not Cancer Driver | No | 55 | 0.107421875 | 70 | 11 | 0.021484375 | 2 |
| ALX4-201 | ALX4 | Q9H161 | Homeobox protein aristaless-like 4 | chr11 | GO:0009952 | Not Cancer Driver | No | 72 | 0.1751824817518248 | 325 | 56 | 0.1362530413625304 | 4 |
| ARC-201 | ARC | Q7LC44 | Activity-regulated cytoskeleton-associated protein | chr8 | GO:0009952 | Not Cancer Driver | No | 57 | 0.1439393939393939 | 199 | 30 | 0.0757575757575757 | 0 |
| BARX1-201 | BARX1 | Q9HBU1 | Homeobox protein BarH-like 1 | chr9 | GO:0009952 | Not Cancer Driver | No | 9 | 0.0354330708661417 | 165 | 7 | 0.0275590551181102 | 0 |
| BHLHE40-201 | BHLHE40 | O14503 | Class E basic helix-loop-helix protein 40 | chr3 | GO:0009952 | Not Cancer Driver | No | 35 | 0.0849514563106796 | 243 | 20 | 0.0485436893203883 | 0 |
| BHLHE41-201 | BHLHE41 | Q9C0J9 | Class E basic helix-loop-helix protein 41 | chr12 | GO:0009952 | Not Cancer Driver | No | 11 | 0.0228215767634854 | 213 | 7 | 0.0145228215767634 | 0 |
| BMPR2-202 | BMPR2 | Q13873 | Bone morphogenetic protein receptor type-2 | chr2 | GO:0009952 | Compendium | Yes | 100 | 0.0963391136801541 | 601 | 49 | 0.0472061657032755 | 17 |
| BPTF-202 | BPTF | Q12830 | Nucleosome-remodeling factor subunit BPTF | chr17 | GO:0009952 | Not Cancer Driver | No | 207 | 0.0679579776756401 | 2190 | 143 | 0.0469468154957321 | 2 |
| BTG2-201 | BTG2 | P78543 | Protein BTG2 | chr1 | GO:0009952 | Census | Yes | 30 | 0.189873417721519 | 7 | 2 | 0.0126582278481012 | 0 |
| CDON-216 | CDON | Q4KMG0 | Cell adhesion molecule-related/down-regulated by oncogenes | chr11 | GO:0009952 | Not Cancer Driver | No | 120 | 0.0932400932400932 | 444 | 42 | 0.0326340326340326 | 5 |
| CER1-201 | CER1 | O95813 | Cerberus | chr9 | GO:0009952 | Not Cancer Driver | No | 53 | 0.198501872659176 | 121 | 19 | 0.0711610486891385 | 0 |
| CFC1-201 | CFC1 | P0CG37 | Cryptic protein | chr2 | GO:0009952 | Not Cancer Driver | No | 22 | 0.0986547085201793 | 68 | 20 | 0.0896860986547085 | 1 |
| CFC1B-201 | CFC1B | P0CG36 | Cryptic family protein 1B | chr2 | GO:0009952 | Not Cancer Driver | No | 0 | 0.0 | 55 | 0 | 0.0 | 0 |
| CRKL-201 | CRKL | P46109 | Crk-like protein | chr22 | GO:0009952 | Not Cancer Driver | No | 24 | 0.0792079207920792 | 160 | 17 | 0.0561056105610561 | 0 |
| CTNNBIP1-203 | CTNNBIP1 | Q9NSA3 | Beta-catenin-interacting protein 1 | chr1 | GO:0009952 | Not Cancer Driver | No | 8 | 0.0987654320987654 | 64 | 7 | 0.0864197530864197 | 0 |
| CYP26C1-202 | CYP26C1 | Q6V0L0 | Cytochrome P450 26C1 | chr10 | GO:0009952 | Not Cancer Driver | No | 26 | 0.0498084291187739 | 56 | 4 | 0.0076628352490421 | 0 |
| EMX2-203 | EMX2 | Q04743 | Homeobox protein EMX2 | chr10 | GO:0009952 | Not Cancer Driver | No | 25 | 0.0992063492063492 | 147 | 18 | 0.0714285714285714 | 0 |
| GLI3-201 | GLI3 | P10071 | Transcriptional activator GLI3 | chr7 | GO:0009952 | Not Cancer Driver | No | 308 | 0.1949367088607595 | 1362 | 270 | 0.170886075949367 | 7 |
| GRSF1-201 | GRSF1 | Q12849 | G-rich sequence factor 1 | chr4 | GO:0009952 | Not Cancer Driver | No | 33 | 0.06875 | 147 | 15 | 0.03125 | 0 |
| HELT-204 | HELT | A6NFD8 | Hairy and enhancer of split-related protein HELT | chr4 | GO:0009952 | Not Cancer Driver | No | 22 | 0.0909090909090909 | 132 | 13 | 0.0537190082644628 | 0 |
| HES1-201 | HES1 | Q14469 | Transcription factor HES-1 | chr3 | GO:0009952 | Not Cancer Driver | No | 35 | 0.125 | 227 | 30 | 0.1071428571428571 | 0 |
| HES2-201 | HES2 | Q9Y543 | Transcription factor HES-2 | chr1 | GO:0009952 | Not Cancer Driver | No | 5 | 0.0289017341040462 | 59 | 1 | 0.0057803468208092 | 0 |
| HES3-201 | HES3 | Q5TGS1 | Transcription factor HES-3 | chr1 | GO:0009952 | Not Cancer Driver | No | 8 | 0.043010752688172 | 131 | 7 | 0.0376344086021505 | 0 |
| HES4-201 | HES4 | Q9HCC6 | Transcription factor HES-4 | chr1 | GO:0009952 | Not Cancer Driver | No | 6 | 0.0271493212669683 | 125 | 4 | 0.0180995475113122 | 0 |
| HES5-201 | HES5 | Q5TA89 | Transcription factor HES-5 | chr1 | GO:0009952 | Not Cancer Driver | No | 1 | 0.0060240963855421 | 73 | 0 | 0.0 | 0 |
| HES6-201 | HES6 | Q96HZ4 | Transcription cofactor HES-6 | chr2 | GO:0009952 | Not Cancer Driver | No | 7 | 0.03125 | 131 | 4 | 0.0178571428571428 | 0 |
| HES7-201 | HES7 | Q9BYE0 | Transcription factor HES-7 | chr17 | GO:0009952 | Not Cancer Driver | No | 4 | 0.0177777777777777 | 167 | 4 | 0.0177777777777777 | 3 |
| HEY1-202 | HEY1 | Q9Y5J3 | Hairy/enhancer-of-split related with YRPW motif protein 1 | chr8 | GO:0009952 | Census | Yes | 26 | 0.0855263157894736 | 172 | 12 | 0.0394736842105263 | 0 |
| HEY2-201 | HEY2 | Q9UBP5 | Hairy/enhancer-of-split related with YRPW motif protein 2 | chr6 | GO:0009952 | Not Cancer Driver | No | 50 | 0.1483679525222551 | 181 | 21 | 0.0623145400593471 | 0 |
| HEYL-201 | HEYL | Q9NQ87 | Hairy/enhancer-of-split related with YRPW motif-like protein | chr1 | GO:0009952 | Not Cancer Driver | No | 29 | 0.0884146341463414 | 199 | 13 | 0.0396341463414634 | 0 |
| HHEX-201 | HHEX | Q03014 | Hematopoietically-expressed homeobox protein HHEX | chr10 | GO:0009952 | Not Cancer Driver | No | 13 | 0.0481481481481481 | 193 | 12 | 0.0444444444444444 | 0 |
| HIPK1-208 | HIPK1 | Q86Z02 | Homeodomain-interacting protein kinase 1 | chr1 | GO:0009952 | Not Cancer Driver | No | 104 | 0.0859504132231405 | 567 | 58 | 0.0479338842975206 | 0 |
| HIPK2-202 | HIPK2 | Q9H2X6 | Homeodomain-interacting protein kinase 2 | chr7 | GO:0009952 | Not Cancer Driver | No | 124 | 0.1035058430717863 | 686 | 76 | 0.0634390651085141 | 0 |
| HNF1B-203 | HNF1B | P35680 | Hepatocyte nuclear factor 1-beta | chr17 | GO:0009952 | Not Cancer Driver | No | 68 | 0.1220825852782764 | 476 | 57 | 0.1023339317773788 | 19 |
| HOXA10-201 | HOXA10 | P31260 | Homeobox protein Hox-A10 | chr7 | GO:0009952 | Not Cancer Driver | No | 30 | 0.073170731707317 | 339 | 22 | 0.0536585365853658 | 0 |
| HOXA11-201 | HOXA11 | P31270 | Homeobox protein Hox-A11 | chr7 | GO:0009952 | Census, Compendium | Yes | 25 | 0.0798722044728434 | 205 | 16 | 0.0511182108626198 | 0 |
| HOXA2-201 | HOXA2 | O43364 | Homeobox protein Hox-A2 | chr7 | GO:0009952 | Not Cancer Driver | No | 49 | 0.1303191489361702 | 281 | 39 | 0.1037234042553191 | 1 |
| HOXA3-206 | HOXA3 | O43365 | Homeobox protein Hox-A3 | chr7 | GO:0009952 | Not Cancer Driver | No | 64 | 0.1444695259593679 | 418 | 64 | 0.1444695259593679 | 0 |
| HOXA4-201 | HOXA4 | Q00056 | Homeobox protein Hox-A4 | chr7 | GO:0009952 | Not Cancer Driver | No | 24 | 0.075 | 258 | 12 | 0.0375 | 0 |
| HOXA5-201 | HOXA5 | P20719 | Homeobox protein Hox-A5 | chr7 | GO:0009952 | Not Cancer Driver | No | 40 | 0.1481481481481481 | 209 | 33 | 0.1222222222222222 | 0 |
| HOXA6-201 | HOXA6 | P31267 | Homeobox protein Hox-A6 | chr7 | GO:0009952 | Not Cancer Driver | No | 36 | 0.1545064377682403 | 91 | 16 | 0.0686695278969957 | 0 |
| HOXA7-201 | HOXA7 | P31268 | Homeobox protein Hox-A7 | chr7 | GO:0009952 | Not Cancer Driver | No | 41 | 0.1782608695652174 | 71 | 4 | 0.017391304347826 | 0 |
| HOXA9-201 | HOXA9 | P31269 | Homeobox protein Hox-A9 | chr7 | GO:0009952 | Census | Yes | 41 | 0.150735294117647 | 189 | 30 | 0.1102941176470588 | 0 |
| HOXB1-201 | HOXB1 | P14653 | Homeobox protein Hox-B1 | chr17 | GO:0009952 | Not Cancer Driver | No | 61 | 0.2026578073089701 | 280 | 60 | 0.1993355481727574 | 1 |
| HOXB2-201 | HOXB2 | P14652 | Homeobox protein Hox-B2 | chr17 | GO:0009952 | Not Cancer Driver | No | 39 | 0.1095505617977528 | 269 | 29 | 0.0814606741573033 | 0 |
| HOXB3-212 | HOXB3 | P14651 | Homeobox protein Hox-B3 | chr17 | GO:0009952 | Not Cancer Driver | No | 59 | 0.1368909512761021 | 399 | 53 | 0.1229698375870069 | 0 |
| HOXB4-201 | HOXB4 | P17483 | Homeobox protein Hox-B4 | chr17 | GO:0009952 | Not Cancer Driver | No | 29 | 0.1155378486055776 | 211 | 22 | 0.0876494023904382 | 0 |
| HOXB5-201 | HOXB5 | P09067 | Homeobox protein Hox-B5 | chr17 | GO:0009952 | Not Cancer Driver | No | 34 | 0.1263940520446096 | 203 | 26 | 0.0966542750929368 | 0 |
| HOXB6-201 | HOXB6 | P17509 | Homeobox protein Hox-B6 | chr17 | GO:0009952 | Not Cancer Driver | No | 24 | 0.1071428571428571 | 103 | 15 | 0.0669642857142857 | 0 |
| HOXB7-201 | HOXB7 | P09629 | Homeobox protein Hox-B7 | chr17 | GO:0009952 | Not Cancer Driver | No | 19 | 0.0875576036866359 | 84 | 8 | 0.0368663594470046 | 0 |
| HOXB8-201 | HOXB8 | P17481 | Homeobox protein Hox-B8 | chr17 | GO:0009952 | Not Cancer Driver | No | 28 | 0.1152263374485596 | 121 | 13 | 0.0534979423868312 | 0 |
| HOXB9-201 | HOXB9 | P17482 | Homeobox protein Hox-B9 | chr17 | GO:0009952 | Not Cancer Driver | No | 23 | 0.092 | 191 | 22 | 0.088 | 0 |
| HOXC10-201 | HOXC10 | Q9NYD6 | Homeobox protein Hox-C10 | chr12 | GO:0009952 | Not Cancer Driver | No | 42 | 0.1228070175438596 | 267 | 32 | 0.0935672514619883 | 0 |
| HOXC11-202 | HOXC11 | O43248 | Homeobox protein Hox-C11 | chr12 | GO:0009952 | Census | Yes | 31 | 0.1019736842105263 | 157 | 16 | 0.0526315789473684 | 0 |
| HOXC13-201 | HOXC13 | P31276 | Homeobox protein Hox-C13 | chr12 | GO:0009952 | Census, Compendium | Yes | 42 | 0.1272727272727272 | 203 | 30 | 0.0909090909090909 | 0 |
| HOXC4-202 | HOXC4 | P09017 | Homeobox protein Hox-C4 | chr12 | GO:0009952 | Not Cancer Driver | No | 32 | 0.1212121212121212 | 228 | 25 | 0.0946969696969697 | 0 |
| HOXC5-201 | HOXC5 | Q00444 | Homeobox protein Hox-C5 | chr12 | GO:0009952 | Not Cancer Driver | No | 31 | 0.1396396396396396 | 142 | 19 | 0.0855855855855855 | 0 |
| HOXC6-201 | HOXC6 | P09630 | Homeobox protein Hox-C6 | chr12 | GO:0009952 | Not Cancer Driver | No | 27 | 0.1148936170212766 | 111 | 16 | 0.0680851063829787 | 0 |
| HOXC8-201 | HOXC8 | P31273 | Homeobox protein Hox-C8 | chr12 | GO:0009952 | Not Cancer Driver | No | 26 | 0.1074380165289256 | 139 | 12 | 0.0495867768595041 | 0 |
| HOXC9-201 | HOXC9 | P31274 | Homeobox protein Hox-C9 | chr12 | GO:0009952 | Not Cancer Driver | No | 25 | 0.0961538461538461 | 144 | 12 | 0.0461538461538461 | 0 |
| HOXD10-201 | HOXD10 | P28358 | Homeobox protein Hox-D10 | chr2 | GO:0009952 | Not Cancer Driver | No | 62 | 0.1823529411764705 | 230 | 46 | 0.1352941176470588 | 1 |
| HOXD13-201 | HOXD13 | P35453 | Homeobox protein Hox-D13 | chr2 | GO:0009952 | Census, Compendium | Yes | 34 | 0.0991253644314868 | 114 | 11 | 0.032069970845481 | 7 |
| HOXD3-205 | HOXD3 | P31249 | Homeobox protein Hox-D3 | chr2 | GO:0009952 | Not Cancer Driver | No | 54 | 0.125 | 358 | 52 | 0.1203703703703703 | 0 |
| HOXD4-201 | HOXD4 | P09016 | Homeobox protein Hox-D4 | chr2 | GO:0009952 | Not Cancer Driver | No | 49 | 0.192156862745098 | 212 | 33 | 0.1294117647058823 | 0 |
| HOXD9-201 | HOXD9 | P28356 | Homeobox protein Hox-D9 | chr2 | GO:0009952 | Not Cancer Driver | No | 31 | 0.0880681818181818 | 277 | 18 | 0.0511363636363636 | 0 |
| KMT2A-201 | KMT2A | Q03164 | Histone-lysine N-methyltransferase 2A | chr11 | GO:0009952 | Census, Compendium | Yes | 342 | 0.0861678004535147 | 3148 | 263 | 0.0662635424540186 | 0 |
| LHX1-201 | LHX1 | P48742 | LIM/homeobox protein Lhx1 | chr17 | GO:0009952 | Not Cancer Driver | No | 37 | 0.0911330049261083 | 268 | 23 | 0.0566502463054187 | 0 |
| LRP5-201 | LRP5 | O75197 | Low-density lipoprotein receptor-related protein 5 | chr11 | GO:0009952 | Not Cancer Driver | No | 196 | 0.1213622291021671 | 189 | 24 | 0.014860681114551 | 54 |
| MLLT3-202 | MLLT3 | P42568 | Protein AF-9 | chr9 | GO:0009952 | Census, Compendium | Yes | 57 | 0.1003521126760563 | 414 | 48 | 0.0845070422535211 | 0 |
| MSX1-201 | MSX1 | P28360 | Homeobox protein MSX-1 | chr4 | GO:0009952 | Not Cancer Driver | No | 32 | 0.1056105610561056 | 199 | 12 | 0.0396039603960396 | 7 |
| MSX2-201 | MSX2 | P35548 | Homeobox protein MSX-2 | chr5 | GO:0009952 | Not Cancer Driver | No | 21 | 0.0786516853932584 | 170 | 10 | 0.0374531835205992 | 3 |
| NEUROD1-201 | NEUROD1 | Q13562 | Neurogenic differentiation factor 1 | chr2 | GO:0009952 | Not Cancer Driver | No | 68 | 0.1910112359550561 | 203 | 42 | 0.1179775280898876 | 2 |
| NR2F2-201 | NR2F2 | P24468 | COUP transcription factor 2 | chr15 | GO:0009952 | Not Cancer Driver | No | 53 | 0.1280193236714976 | 102 | 1 | 0.002415458937198 | 6 |
| OTX1-201 | OTX1 | P32242 | Homeobox protein OTX1 | chr2 | GO:0009952 | Not Cancer Driver | No | 12 | 0.0338983050847457 | 248 | 10 | 0.0282485875706214 | 0 |
| PBX1-203 | PBX1 | P40424 | Pre-B-cell leukemia transcription factor 1 | chr1 | GO:0009952 | Census | Yes | 64 | 0.1488372093023255 | 291 | 44 | 0.1023255813953488 | 0 |
| PCGF2-207 | PCGF2 | P35227 | Polycomb group RING finger protein 2 | chr17 | GO:0009952 | Not Cancer Driver | No | 36 | 0.1046511627906976 | 161 | 10 | 0.0290697674418604 | 1 |
| PCSK5-205 | PCSK5 | Q92824 | Proprotein convertase subtilisin/kexin type 5 | chr9 | GO:0009952 | Not Cancer Driver | No | 259 | 0.139247311827957 | 170 | 20 | 0.010752688172043 | 0 |
| RARG-203 | RARG | P13631 | Retinoic acid receptor gamma | chr12 | GO:0009952 | Not Cancer Driver | No | 69 | 0.1519823788546255 | 164 | 24 | 0.052863436123348 | 0 |
| RING1-201 | RING1 | Q06587 | E3 ubiquitin-protein ligase RING1 | chr6 | GO:0009952 | Not Cancer Driver | No | 47 | 0.1157635467980295 | 302 | 38 | 0.0935960591133004 | 0 |
| SMAD2-201 | SMAD2 | Q15796 | Mothers against decapentaplegic homolog 2 | chr18 | GO:0009952 | Census, Compendium | Yes | 58 | 0.1241970021413276 | 137 | 11 | 0.0235546038543897 | 3 |
| SMO-201 | SMO | Q99835 | Protein smoothened | chr7 | GO:0009952 | Census, Compendium | Yes | 88 | 0.1118170266836086 | 242 | 20 | 0.025412960609911 | 1 |
| TBX1-201 | TBX1 | O43435 | T-box transcription factor TBX1 | chr22 | GO:0009952 | Not Cancer Driver | No | 13 | 0.0326633165829145 | 198 | 1 | 0.0025125628140703 | 4 |
| TDGF1-201 | TDGF1 | P13385 | Teratocarcinoma-derived growth factor 1 | chr3 | GO:0009952 | Not Cancer Driver | No | 34 | 0.1808510638297872 | 25 | 2 | 0.0106382978723404 | 0 |
| TDGF1P3-201 | TDGF1P3 | P51864 | Putative teratocarcinoma-derived growth factor 3 | chrX | GO:0009952 | Not Cancer Driver | No | 0 | 0.0 | 24 | 0 | 0.0 | 0 |
| TGFBR1-202 | TGFBR1 | P36897 | TGF-beta receptor type-1 | chr9 | GO:0009952 | Not Cancer Driver | No | 57 | 0.1133200795228628 | 23 | 3 | 0.0059642147117296 | 13 |
| TSHZ1-204 | TSHZ1 | Q6ZSZ6 | Teashirt homolog 1 | chr18 | GO:0009952 | Not Cancer Driver | No | 115 | 0.10677808727948 | 804 | 93 | 0.0863509749303621 | 0 |
| TULP3-202 | TULP3 | O75386 | Tubby-related protein 3 | chr12 | GO:0009952 | Not Cancer Driver | No | 54 | 0.1221719457013574 | 218 | 26 | 0.0588235294117647 | 1 |
| WIF1-201 | WIF1 | Q9Y5W5 | Wnt inhibitory factor 1 | chr12 | GO:0009952 | Census | Yes | 62 | 0.1635883905013192 | 30 | 4 | 0.0105540897097625 | 0 |
| YY1-201 | YY1 | P25490 | Transcriptional repressor protein YY1 | chr14 | GO:0009952 | Not Cancer Driver | No | 29 | 0.0700483091787439 | 337 | 21 | 0.0507246376811594 | 2 |
| ZBTB16-201 | ZBTB16 | Q05516 | Zinc finger and BTB domain-containing protein 16 | chr11 | GO:0009952 | Census, Compendium | Yes | 105 | 0.1560178306092124 | 268 | 42 | 0.0624071322436849 | 1 |