Total number of protein in "GO:0010506" GO term: 71
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1-201 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0010506 | Census, Compendium | Yes | 106 | 0.0938053097345132 | 609 | 53 | 0.0469026548672566 | 2 |
| ABL2-203 | ABL2 | P42684 | Tyrosine-protein kinase ABL2 | chr1 | GO:0010506 | Census, Compendium | Yes | 125 | 0.1057529610829103 | 644 | 53 | 0.0448392554991539 | 0 |
| ACER2-201 | ACER2 | Q5QJU3 | Alkaline ceramidase 2 | chr9 | GO:0010506 | Not Cancer Driver | No | 24 | 0.0872727272727272 | 0 | 0 | 0.0 | 0 |
| ATM-229 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0010506 | Census, Compendium | Yes | 358 | 0.1171465968586387 | 226 | 29 | 0.0094895287958115 | 41 |
| BECN1-213 | BECN1 | Q14457 | Beclin-1 | chr17 | GO:0010506 | Not Cancer Driver | No | 36 | 0.08 | 190 | 15 | 0.0333333333333333 | 0 |
| BOK-201 | BOK | Q9UMX3 | Bcl-2-related ovarian killer protein | chr2 | GO:0010506 | Not Cancer Driver | No | 5 | 0.0235849056603773 | 0 | 0 | 0.0 | 0 |
| C9orf72-203 | C9orf72 | Q96LT7 | Guanine nucleotide exchange factor C9orf72 | chr9 | GO:0010506 | Not Cancer Driver | No | 41 | 0.0852390852390852 | 11 | 0 | 0.0 | 0 |
| CHMP4B-201 | CHMP4B | Q9H444 | Charged multivesicular body protein 4b | chr20 | GO:0010506 | Not Cancer Driver | No | 21 | 0.09375 | 201 | 20 | 0.0892857142857142 | 2 |
| CISD1-201 | CISD1 | Q9NZ45 | CDGSH iron-sulfur domain-containing protein 1 | chr10 | GO:0010506 | Not Cancer Driver | No | 4 | 0.037037037037037 | 18 | 0 | 0.0 | 0 |
| CISD2-201 | CISD2 | Q8N5K1 | CDGSH iron-sulfur domain-containing protein 2 | chr4 | GO:0010506 | Not Cancer Driver | No | 6 | 0.0444444444444444 | 7 | 0 | 0.0 | 0 |
| CRYBA1-201 | CRYBA1 | P05813 | Beta-crystallin A3 | chr17 | GO:0010506 | Not Cancer Driver | No | 18 | 0.0837209302325581 | 52 | 4 | 0.0186046511627906 | 0 |
| DAPK1-202 | DAPK1 | P53355 | Death-associated protein kinase 1 | chr9 | GO:0010506 | Not Cancer Driver | No | 149 | 0.1041958041958042 | 116 | 12 | 0.0083916083916083 | 0 |
| DAPK2-202 | DAPK2 | Q9UIK4 | Death-associated protein kinase 2 | chr15 | GO:0010506 | Not Cancer Driver | No | 40 | 0.1081081081081081 | 54 | 7 | 0.0189189189189189 | 0 |
| DAPK3-202 | DAPK3 | O43293 | Death-associated protein kinase 3 | chr19 | GO:0010506 | Not Cancer Driver | No | 45 | 0.0991189427312775 | 82 | 6 | 0.013215859030837 | 0 |
| DCAF12-201 | DCAF12 | Q5T6F0 | DDB1- and CUL4-associated factor 12 | chr9 | GO:0010506 | Not Cancer Driver | No | 46 | 0.1015452538631346 | 70 | 5 | 0.0110375275938189 | 0 |
| DDIT3-201 | DDIT3 | P35638 | DNA damage-inducible transcript 3 protein | chr12 | GO:0010506 | Census | Yes | 19 | 0.1124260355029585 | 161 | 17 | 0.1005917159763313 | 0 |
| DEPP1-201 | DEPP1 | Q9NTK1 | Protein DEPP1 | chr10 | GO:0010506 | Not Cancer Driver | No | 24 | 0.1132075471698113 | 201 | 24 | 0.1132075471698113 | 0 |
| DRAM1-201 | DRAM1 | Q8N682 | DNA damage-regulated autophagy modulator protein 1 | chr12 | GO:0010506 | Not Cancer Driver | No | 20 | 0.0840336134453781 | 0 | 0 | 0.0 | 0 |
| DRAM2-207 | DRAM2 | Q6UX65 | DNA damage-regulated autophagy modulator protein 2 | chr1 | GO:0010506 | Not Cancer Driver | No | 18 | 0.0676691729323308 | 0 | 0 | 0.0 | 3 |
| ENST00000481848 | SOGA3 | Q5TF21 | Protein SOGA3 | chr6 | GO:0010506 | Not Cancer Driver | No | 132 | 0.1393875395987328 | 797 | 107 | 0.1129883843717001 | 0 |
| ENST00000593731 | PIK3R2 | O00459 | Phosphatidylinositol 3-kinase regulatory subunit beta | chr19 | GO:0010506 | Not Cancer Driver | No | 83 | 0.114010989010989 | 418 | 40 | 0.0549450549450549 | 3 |
| EP300-201 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | GO:0010506 | Census, Compendium | Yes | 203 | 0.084092792046396 | 1792 | 84 | 0.0347970173985087 | 1 |
| ERCC4-201 | ERCC4 | Q92889 | DNA repair endonuclease XPF | chr16 | GO:0010506 | Census | Yes | 81 | 0.0884279475982532 | 226 | 19 | 0.0207423580786026 | 15 |
| FBXL2-216 | FBXL2 | Q9UKC9 | F-box/LRR-repeat protein 2 | chr3 | GO:0010506 | Not Cancer Driver | No | 31 | 0.0732860520094562 | 0 | 0 | 0.0 | 0 |
| GPR137-203 | GPR137 | Q96N19 | Integral membrane protein GPR137 | chr11 | GO:0010506 | Not Cancer Driver | No | 49 | 0.1175059952038369 | 41 | 7 | 0.0167865707434052 | 0 |
| GPR137B-202 | GPR137B | O60478 | Integral membrane protein GPR137B | chr1 | GO:0010506 | Not Cancer Driver | No | 39 | 0.0977443609022556 | 48 | 1 | 0.0025062656641604 | 0 |
| HDAC6-201 | HDAC6 | Q9UBN7 | Histone deacetylase 6 | chrX | GO:0010506 | Not Cancer Driver | No | 122 | 0.1004115226337448 | 409 | 35 | 0.0288065843621399 | 0 |
| HSPB1-201 | HSPB1 | P04792 | Heat shock protein beta-1 | chr7 | GO:0010506 | Not Cancer Driver | No | 10 | 0.048780487804878 | 118 | 8 | 0.0390243902439024 | 19 |
| IFI16-201 | IFI16 | Q16666 | Gamma-interferon-inducible protein 16 | chr1 | GO:0010506 | Not Cancer Driver | No | 102 | 0.129936305732484 | 422 | 61 | 0.0777070063694267 | 0 |
| ITPR1-237 | ITPR1 | Q14643 | Inositol 1,4,5-trisphosphate receptor type 1 | chr3 | GO:0010506 | Not Cancer Driver | No | 272 | 0.0986221899927483 | 581 | 56 | 0.0203045685279187 | 6 |
| KAT8-201 | KAT8 | Q9H7Z6 | Histone acetyltransferase KAT8 | chr16 | GO:0010506 | Not Cancer Driver | No | 57 | 0.1244541484716157 | 156 | 18 | 0.0393013100436681 | 4 |
| KEAP1-201 | KEAP1 | Q14145 | Kelch-like ECH-associated protein 1 | chr19 | GO:0010506 | Census, Compendium | Yes | 217 | 0.3477564102564102 | 57 | 7 | 0.0112179487179487 | 0 |
| LAMP3-201 | LAMP3 | Q9UQV4 | Lysosome-associated membrane glycoprotein 3 | chr3 | GO:0010506 | Not Cancer Driver | No | 57 | 0.1370192307692307 | 223 | 34 | 0.0817307692307692 | 0 |
| LRRK2-201 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | GO:0010506 | Not Cancer Driver | No | 402 | 0.1590819153146023 | 91 | 13 | 0.0051444400474871 | 20 |
| MAPK15-201 | MAPK15 | Q8TD08 | Mitogen-activated protein kinase 15 | chr8 | GO:0010506 | Not Cancer Driver | No | 66 | 0.1213235294117647 | 236 | 32 | 0.0588235294117647 | 0 |
| MAPT-212 | MAPT | P10636 | Microtubule-associated protein tau | chr17 | GO:0010506 | Not Cancer Driver | No | 100 | 0.1319261213720316 | 750 | 99 | 0.1306068601583113 | 17 |
| MFSD8-241 | MFSD8 | Q8NHS3 | Major facilitator superfamily domain-containing protein 8 | chr4 | GO:0010506 | Not Cancer Driver | No | 53 | 0.1023166023166023 | 15 | 3 | 0.0057915057915057 | 14 |
| MTCL1-201 | MTCL1 | Q9Y4B5 | Microtubule cross-linking factor 1 | chr18 | GO:0010506 | Not Cancer Driver | No | 199 | 0.1044619422572178 | 1695 | 169 | 0.0887139107611548 | 0 |
| MTMR3-204 | MTMR3 | Q13615 | Myotubularin-related protein 3 | chr22 | GO:0010506 | Not Cancer Driver | No | 101 | 0.0843071786310517 | 501 | 48 | 0.0400667779632721 | 0 |
| MTMR4-201 | MTMR4 | Q9NYA4 | Myotubularin-related protein 4 | chr17 | GO:0010506 | Not Cancer Driver | No | 104 | 0.0870292887029288 | 476 | 43 | 0.0359832635983263 | 0 |
| NLRP6-201 | NLRP6 | P59044 | NACHT, LRR and PYD domains-containing protein 6 | chr11 | GO:0010506 | Not Cancer Driver | No | 68 | 0.0762331838565022 | 205 | 11 | 0.0123318385650224 | 0 |
| NUPR1-201 | NUPR1 | O60356 | Nuclear protein 1 | chr16 | GO:0010506 | Not Cancer Driver | No | 10 | 0.1219512195121951 | 82 | 10 | 0.1219512195121951 | 0 |
| OSBPL7-201 | OSBPL7 | Q9BZF2 | Oxysterol-binding protein-related protein 7 | chr17 | GO:0010506 | Not Cancer Driver | No | 88 | 0.1045130641330166 | 396 | 37 | 0.0439429928741092 | 0 |
| PIK3C3-201 | PIK3C3 | Q8NEB9 | Phosphatidylinositol 3-kinase catalytic subunit type 3 | chr18 | GO:0010506 | Not Cancer Driver | No | 101 | 0.1138669673055242 | 192 | 28 | 0.0315670800450958 | 0 |
| PIK3R2-201 | PIK3R2 | O00459 | Phosphatidylinositol 3-kinase regulatory subunit beta | chr19 | GO:0010506 | Not Cancer Driver | No | 83 | 0.114010989010989 | 418 | 40 | 0.0549450549450549 | 3 |
| PIK3R4-201 | PIK3R4 | Q99570 | Phosphoinositide 3-kinase regulatory subunit 4 | chr3 | GO:0010506 | Not Cancer Driver | No | 133 | 0.0979381443298969 | 315 | 32 | 0.0235640648011782 | 0 |
| PIP4K2A-202 | PIP4K2A | P48426 | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha | chr10 | GO:0010506 | Not Cancer Driver | No | 41 | 0.1009852216748768 | 123 | 12 | 0.0295566502463054 | 0 |
| PIP4K2B-204 | PIP4K2B | P78356 | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | chr17 | GO:0010506 | Not Cancer Driver | No | 35 | 0.0841346153846153 | 112 | 12 | 0.0288461538461538 | 0 |
| PIP4K2C-201 | PIP4K2C | Q8TBX8 | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma | chr12 | GO:0010506 | Not Cancer Driver | No | 43 | 0.1021377672209026 | 112 | 16 | 0.0380047505938242 | 0 |
| PRKN-206 | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:0010506 | Not Cancer Driver | No | 96 | 0.2064516129032258 | 78 | 14 | 0.0301075268817204 | 30 |
| PSAP-201 | PSAP | P07602 | Prosaposin | chr10 | GO:0010506 | Not Cancer Driver | No | 46 | 0.0877862595419847 | 28 | 2 | 0.0038167938931297 | 7 |
| PYCARD-201 | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:0010506 | Not Cancer Driver | No | 12 | 0.0615384615384615 | 39 | 4 | 0.0205128205128205 | 0 |
| RAB39B-201 | RAB39B | Q96DA2 | Ras-related protein Rab-39B | chrX | GO:0010506 | Not Cancer Driver | No | 32 | 0.1502347417840375 | 0 | 0 | 0.0 | 2 |
| RAB8A-201 | RAB8A | P61006 | Ras-related protein Rab-8A | chr19 | GO:0010506 | Not Cancer Driver | No | 30 | 0.144927536231884 | 26 | 3 | 0.0144927536231884 | 0 |
| RMC1-201 | RMC1 | Q96DM3 | Regulator of MON1-CCZ1 complex | chr18 | GO:0010506 | Not Cancer Driver | No | 51 | 0.0776255707762557 | 12 | 0 | 0.0 | 0 |
| ROCK1-201 | ROCK1 | Q13464 | Rho-associated protein kinase 1 | chr18 | GO:0010506 | Not Cancer Driver | No | 116 | 0.0856720827178729 | 780 | 61 | 0.0450516986706056 | 0 |
| RPTOR-201 | RPTOR | Q8N122 | Regulatory-associated protein of mTOR | chr17 | GO:0010506 | Not Cancer Driver | No | 149 | 0.1116104868913857 | 242 | 18 | 0.0134831460674157 | 0 |
| SMCR8-201 | SMCR8 | Q8TEV9 | Guanine nucleotide exchange protein SMCR8 | chr17 | GO:0010506 | Not Cancer Driver | No | 76 | 0.0811099252934898 | 357 | 30 | 0.032017075773746 | 0 |
| SOGA3-203 | SOGA3 | Q5TF21 | Protein SOGA3 | chr6 | GO:0010506 | Not Cancer Driver | No | 132 | 0.1393875395987328 | 795 | 109 | 0.1151003167898627 | 0 |
| TPCN2-201 | TPCN2 | Q8NHX9 | Two pore channel protein 2 | chr11 | GO:0010506 | Not Cancer Driver | No | 43 | 0.0571808510638297 | 16 | 0 | 0.0 | 0 |
| TRIB3-201 | TRIB3 | Q96RU7 | Tribbles homolog 3 | chr20 | GO:0010506 | Not Cancer Driver | No | 45 | 0.1256983240223463 | 113 | 17 | 0.047486033519553 | 0 |
| ULK3-201 | ULK3 | Q6PHR2 | Serine/threonine-protein kinase ULK3 | chr15 | GO:0010506 | Not Cancer Driver | No | 26 | 0.0550847457627118 | 55 | 2 | 0.0042372881355932 | 0 |
| USP10-201 | USP10 | Q14694 | Ubiquitin carboxyl-terminal hydrolase 10 | chr16 | GO:0010506 | Not Cancer Driver | No | 65 | 0.081453634085213 | 423 | 34 | 0.0426065162907268 | 0 |
| USP13-201 | USP13 | Q92995 | Ubiquitin carboxyl-terminal hydrolase 13 | chr3 | GO:0010506 | Not Cancer Driver | No | 96 | 0.1112398609501738 | 224 | 34 | 0.0393974507531865 | 0 |
| USP33-203 | USP33 | Q8TEY7 | Ubiquitin carboxyl-terminal hydrolase 33 | chr1 | GO:0010506 | Not Cancer Driver | No | 95 | 0.1008492569002123 | 257 | 33 | 0.0350318471337579 | 0 |
| UVRAG-201 | UVRAG | Q9P2Y5 | UV radiation resistance-associated gene protein | chr11 | GO:0010506 | Not Cancer Driver | No | 58 | 0.0829756795422031 | 243 | 21 | 0.0300429184549356 | 0 |
| VPS29-206 | VPS29 | Q9UBQ0 | Vacuolar protein sorting-associated protein 29 | chr12 | GO:0010506 | Not Cancer Driver | No | 15 | 0.0824175824175824 | 0 | 0 | 0.0 | 0 |
| WAC-203 | WAC | Q9BTA9 | WW domain-containing adapter protein with coiled-coil | chr10 | GO:0010506 | Not Cancer Driver | No | 78 | 0.1205564142194745 | 572 | 70 | 0.1081916537867078 | 0 |
| WDR24-202 | WDR24 | Q96S15 | GATOR complex protein WDR24 | chr16 | GO:0010506 | Not Cancer Driver | No | 66 | 0.0835443037974683 | 151 | 12 | 0.0151898734177215 | 0 |
| WDR41-201 | WDR41 | Q9HAD4 | WD repeat-containing protein 41 | chr5 | GO:0010506 | Not Cancer Driver | No | 34 | 0.074074074074074 | 23 | 2 | 0.0043572984749455 | 0 |
| ZMPSTE24-201 | ZMPSTE24 | O75844 | CAAX prenyl protease 1 homolog | chr1 | GO:0010506 | Not Cancer Driver | No | 46 | 0.0968421052631579 | 23 | 0 | 0.0 | 3 |