Total number of protein in "GO:0010507" GO term: 58
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADRA1A-204 | ADRA1A | P35348 | Alpha-1A adrenergic receptor | chr8 | GO:0010507 | Not Cancer Driver | No | 90 | 0.1931330472103004 | 40 | 1 | 0.0021459227467811 | 0 |
| AKT1-218 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0010507 | Census, Compendium | Yes | 99 | 0.20625 | 158 | 19 | 0.0395833333333333 | 4 |
| BCL2-201 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:0010507 | Census, Compendium | Yes | 21 | 0.0878661087866108 | 73 | 5 | 0.0209205020920502 | 0 |
| BMF-201 | BMF | Q96LC9 | Bcl-2-modifying factor | chr15 | GO:0010507 | Not Cancer Driver | No | 16 | 0.0869565217391304 | 94 | 7 | 0.0380434782608695 | 0 |
| CPTP-201 | CPTP | Q5TA50 | Ceramide-1-phosphate transfer protein | chr1 | GO:0010507 | Not Cancer Driver | No | 12 | 0.0560747663551401 | 4 | 0 | 0.0 | 0 |
| DAP-201 | DAP | P51397 | Death-associated protein 1 | chr5 | GO:0010507 | Not Cancer Driver | No | 8 | 0.0784313725490196 | 102 | 8 | 0.0784313725490196 | 0 |
| DAPL1-201 | DAPL1 | A0PJW8 | Death-associated protein-like 1 | chr2 | GO:0010507 | Not Cancer Driver | No | 7 | 0.0654205607476635 | 69 | 3 | 0.02803738317757 | 0 |
| EIF4E-203 | EIF4E | P06730 | Eukaryotic translation initiation factor 4E | chr4 | GO:0010507 | Not Cancer Driver | No | 18 | 0.0829493087557603 | 54 | 4 | 0.0184331797235023 | 0 |
| EIF4G1-202 | EIF4G1 | Q04637 | Eukaryotic translation initiation factor 4 gamma 1 | chr3 | GO:0010507 | Not Cancer Driver | No | 157 | 0.0981863664790494 | 1080 | 103 | 0.0644152595372107 | 2 |
| EIF4G2-201 | EIF4G2 | P78344 | Eukaryotic translation initiation factor 4 gamma 2 | chr11 | GO:0010507 | Not Cancer Driver | No | 80 | 0.0882028665931642 | 382 | 38 | 0.041896361631753 | 0 |
| EIF4G3-201 | EIF4G3 | O43432 | Eukaryotic translation initiation factor 4 gamma 3 | chr1 | GO:0010507 | Not Cancer Driver | No | 157 | 0.0990536277602523 | 1018 | 96 | 0.0605678233438485 | 0 |
| EP300-201 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | GO:0010507 | Census, Compendium | Yes | 203 | 0.084092792046396 | 1792 | 84 | 0.0347970173985087 | 1 |
| ERFE-207 | ERFE | Q4G0M1 | Erythroferrone | chr2 | GO:0010507 | Not Cancer Driver | No | 3 | 0.0084745762711864 | 180 | 0 | 0.0 | 0 |
| FOXK1-201 | FOXK1 | P85037 | Forkhead box protein K1 | chr7 | GO:0010507 | Not Cancer Driver | No | 68 | 0.0927694406548431 | 514 | 46 | 0.0627557980900409 | 0 |
| FOXK2-201 | FOXK2 | Q01167 | Forkhead box protein K2 | chr17 | GO:0010507 | Not Cancer Driver | No | 65 | 0.0984848484848484 | 550 | 55 | 0.0833333333333333 | 0 |
| GATA4-201 | GATA4 | P43694 | Transcription factor GATA-4 | chr8 | GO:0010507 | Not Cancer Driver | No | 34 | 0.0769230769230769 | 297 | 23 | 0.0520361990950226 | 21 |
| GOLGA2-201 | GOLGA2 | Q08379 | Golgin subfamily A member 2 | chr9 | GO:0010507 | Not Cancer Driver | No | 84 | 0.0838323353293413 | 859 | 71 | 0.0708582834331337 | 0 |
| HERC1-201 | HERC1 | Q15751 | Probable E3 ubiquitin-protein ligase HERC1 | chr15 | GO:0010507 | Not Cancer Driver | No | 350 | 0.0720016457519029 | 1353 | 102 | 0.0209833367619831 | 1 |
| HGF-201 | HGF | P14210 | Hepatocyte growth factor | chr7 | GO:0010507 | Compendium | Yes | 196 | 0.2692307692307692 | 43 | 16 | 0.0219780219780219 | 0 |
| IL10-202 | IL10 | P22301 | Interleukin-10 | chr1 | GO:0010507 | Not Cancer Driver | No | 17 | 0.095505617977528 | 23 | 1 | 0.0056179775280898 | 0 |
| IL10RA-201 | IL10RA | Q13651 | Interleukin-10 receptor subunit alpha | chr11 | GO:0010507 | Not Cancer Driver | No | 64 | 0.1107266435986159 | 223 | 26 | 0.0449826989619377 | 7 |
| KDM4A-201 | KDM4A | O75164 | Lysine-specific demethylase 4A | chr1 | GO:0010507 | Not Cancer Driver | No | 90 | 0.0845864661654135 | 341 | 35 | 0.0328947368421052 | 0 |
| KIF25-205 | KIF25 | Q9UIL4 | Kinesin-like protein KIF25 | chr6 | GO:0010507 | Not Cancer Driver | No | 58 | 0.1510416666666666 | 139 | 22 | 0.0572916666666666 | 0 |
| KLHL22-201 | KLHL22 | Q53GT1 | Kelch-like protein 22 | chr22 | GO:0010507 | Not Cancer Driver | No | 75 | 0.1182965299684542 | 50 | 7 | 0.0110410094637223 | 0 |
| LEP-201 | LEP | P41159 | Leptin | chr7 | GO:0010507 | Not Cancer Driver | No | 20 | 0.1197604790419161 | 0 | 0 | 0.0 | 2 |
| LEPR-202 | LEPR | P48357 | Leptin receptor | chr1 | GO:0010507 | Not Cancer Driver | No | 178 | 0.1527896995708154 | 57 | 10 | 0.0085836909871244 | 0 |
| MAGEA3-201 | MAGEA3 | P43357 | Melanoma-associated antigen 3 | chrX | GO:0010507 | Not Cancer Driver | No | 74 | 0.2356687898089172 | 104 | 16 | 0.0509554140127388 | 0 |
| MAGEA6-201 | MAGEA6 | P43360 | Melanoma-associated antigen 6 | chrX | GO:0010507 | Not Cancer Driver | No | 56 | 0.1783439490445859 | 104 | 15 | 0.0477707006369426 | 0 |
| MCL1-202 | MCL1 | Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | chr1 | GO:0010507 | Not Cancer Driver | No | 27 | 0.0771428571428571 | 204 | 19 | 0.0542857142857142 | 0 |
| MET-202 | MET | P08581 | Hepatocyte growth factor receptor | chr7 | GO:0010507 | Census, Compendium | Yes | 161 | 0.1158273381294964 | 62 | 10 | 0.0071942446043165 | 16 |
| MLST8-232 | MLST8 | Q9BVC4 | Target of rapamycin complex subunit LST8 | chr16 | GO:0010507 | Not Cancer Driver | No | 24 | 0.0736196319018405 | 45 | 3 | 0.00920245398773 | 0 |
| MTMR9-201 | MTMR9 | Q96QG7 | Myotubularin-related protein 9 | chr8 | GO:0010507 | Not Cancer Driver | No | 38 | 0.0692167577413479 | 45 | 4 | 0.0072859744990892 | 0 |
| MTOR-201 | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | GO:0010507 | Census, Compendium | Yes | 298 | 0.1169085916045508 | 298 | 28 | 0.0109846998823067 | 15 |
| NUPR1-201 | NUPR1 | O60356 | Nuclear protein 1 | chr16 | GO:0010507 | Not Cancer Driver | No | 10 | 0.1219512195121951 | 82 | 10 | 0.1219512195121951 | 0 |
| PTPN22-201 | PTPN22 | Q9Y2R2 | Tyrosine-protein phosphatase non-receptor type 22 | chr1 | GO:0010507 | Not Cancer Driver | No | 107 | 0.1325898389095415 | 344 | 44 | 0.0545229244114002 | 4 |
| RASIP1-201 | RASIP1 | Q5U651 | Ras-interacting protein 1 | chr19 | GO:0010507 | Not Cancer Driver | No | 59 | 0.0612668743509865 | 506 | 39 | 0.0404984423676012 | 0 |
| RNF5-203 | RNF5 | Q99942 | E3 ubiquitin-protein ligase RNF5 | chr6 | GO:0010507 | Not Cancer Driver | No | 12 | 0.0666666666666666 | 69 | 1 | 0.0055555555555555 | 0 |
| RPTOR-201 | RPTOR | Q8N122 | Regulatory-associated protein of mTOR | chr17 | GO:0010507 | Not Cancer Driver | No | 149 | 0.1116104868913857 | 242 | 18 | 0.0134831460674157 | 0 |
| RRAGA-201 | RRAGA | Q7L523 | Ras-related GTP-binding protein A | chr9 | GO:0010507 | Not Cancer Driver | No | 22 | 0.0702875399361022 | 0 | 0 | 0.0 | 0 |
| RRAGB-201 | RRAGB | Q5VZM2 | Ras-related GTP-binding protein B | chrX | GO:0010507 | Not Cancer Driver | No | 42 | 0.1122994652406417 | 37 | 2 | 0.0053475935828877 | 0 |
| RRAGC-201 | RRAGC | Q9HB90 | Ras-related GTP-binding protein C | chr1 | GO:0010507 | Compendium | Yes | 20 | 0.050125313283208 | 61 | 1 | 0.0025062656641604 | 0 |
| RRAGD-202 | RRAGD | Q9NQL2 | Ras-related GTP-binding protein D | chr6 | GO:0010507 | Not Cancer Driver | No | 25 | 0.0625 | 84 | 2 | 0.005 | 4 |
| RUBCN-202 | RUBCN | Q92622 | Run domain Beclin-1-interacting and cysteine-rich domain-containing protein | chr3 | GO:0010507 | Not Cancer Driver | No | 103 | 0.1059670781893004 | 404 | 42 | 0.0432098765432098 | 0 |
| SIRT2-201 | SIRT2 | Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2 | chr19 | GO:0010507 | Not Cancer Driver | No | 40 | 0.1028277634961439 | 85 | 13 | 0.0334190231362467 | 0 |
| SLC7A5-201 | SLC7A5 | Q01650 | Large neutral amino acids transporter small subunit 1 | chr16 | GO:0010507 | Not Cancer Driver | No | 48 | 0.0946745562130177 | 35 | 0 | 0.0 | 0 |
| STAT3-201 | STAT3 | P40763 | Signal transducer and activator of transcription 3 | chr17 | GO:0010507 | Census, Compendium | Yes | 93 | 0.1207792207792207 | 152 | 16 | 0.0207792207792207 | 15 |
| STK38L-201 | STK38L | Q9Y2H1 | Serine/threonine-protein kinase 38-like | chr12 | GO:0010507 | Not Cancer Driver | No | 31 | 0.0668103448275862 | 86 | 6 | 0.0129310344827586 | 0 |
| TAB2-208 | TAB2 | Q9NYJ8 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 | chr6 | GO:0010507 | Not Cancer Driver | No | 61 | 0.088023088023088 | 573 | 51 | 0.0735930735930736 | 2 |
| TAB3-201 | TAB3 | Q8N5C8 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 | chrX | GO:0010507 | Not Cancer Driver | No | 100 | 0.1404494382022472 | 654 | 88 | 0.1235955056179775 | 0 |
| TBC1D14-201 | TBC1D14 | Q9P2M4 | TBC1 domain family member 14 | chr4 | GO:0010507 | Not Cancer Driver | No | 60 | 0.0865800865800865 | 313 | 29 | 0.0418470418470418 | 0 |
| TLK2-201 | TLK2 | Q86UE8 | Serine/threonine-protein kinase tousled-like 2 | chr17 | GO:0010507 | Not Cancer Driver | No | 73 | 0.0945595854922279 | 436 | 31 | 0.0401554404145077 | 6 |
| TREM2-202 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:0010507 | Not Cancer Driver | No | 31 | 0.1347826086956521 | 27 | 2 | 0.008695652173913 | 1 |
| TRIM27-202 | TRIM27 | P14373 | Zinc finger protein RFP | chr6 | GO:0010507 | Census | Yes | 46 | 0.0896686159844054 | 87 | 9 | 0.0175438596491228 | 0 |
| VHL-201 | VHL | P40337 | von Hippel-Lindau disease tumor suppressor | chr3 | GO:0010507 | Census, Compendium | Yes | 85 | 0.3990610328638497 | 117 | 15 | 0.0704225352112676 | 84 |
| WASHC1-203 | WASHC1 | A8K0Z3 | WASH complex subunit 1 | chr9 | GO:0010507 | Not Cancer Driver | No | 0 | 0.0 | 340 | 0 | 0.0 | 0 |
| WDR6-220 | WDR6 | Q9NNW5 | WD repeat-containing protein 6 | chr3 | GO:0010507 | Not Cancer Driver | No | 128 | 0.1141837644959857 | 105 | 9 | 0.0080285459411239 | 0 |
| WNK1-201 | WNK1 | Q9H4A3 | Serine/threonine-protein kinase WNK1 | chr12 | GO:0010507 | Not Cancer Driver | No | 129 | 0.0541561712846347 | 1948 | 115 | 0.0482787573467674 | 0 |
| ZKSCAN3-201 | ZKSCAN3 | Q9BRR0 | Zinc finger protein with KRAB and SCAN domains 3 | chr6 | GO:0010507 | Not Cancer Driver | No | 50 | 0.0929368029739776 | 270 | 24 | 0.0446096654275092 | 0 |