Total number of protein in "GO:0010508" GO term: 81
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AMBRA1-213 | AMBRA1 | Q9C0C7 | Activating molecule in BECN1-regulated autophagy protein 1 | chr11 | GO:0010508 | Not Cancer Driver | No | 132 | 0.1016949152542373 | 790 | 80 | 0.061633281972265 | 0 |
| ATF6-201 | ATF6 | P18850 | Cyclic AMP-dependent transcription factor ATF-6 alpha | chr1 | GO:0010508 | Not Cancer Driver | No | 62 | 0.0925373134328358 | 474 | 43 | 0.0641791044776119 | 2 |
| ATG101-201 | ATG101 | Q9BSB4 | Autophagy-related protein 101 | chr12 | GO:0010508 | Not Cancer Driver | No | 16 | 0.073394495412844 | 5 | 0 | 0.0 | 0 |
| ATG13-201 | ATG13 | O75143 | Autophagy-related protein 13 | chr11 | GO:0010508 | Not Cancer Driver | No | 44 | 0.0851063829787234 | 205 | 20 | 0.0386847195357833 | 0 |
| ATG16L1-203 | ATG16L1 | Q676U5 | Autophagy-related protein 16-1 | chr2 | GO:0010508 | Not Cancer Driver | No | 54 | 0.0889621087314662 | 240 | 19 | 0.0313014827018121 | 1 |
| BAD-201 | BAD | Q92934 | Bcl2-associated agonist of cell death | chr11 | GO:0010508 | Not Cancer Driver | No | 10 | 0.0595238095238095 | 165 | 10 | 0.0595238095238095 | 0 |
| BECN1-213 | BECN1 | Q14457 | Beclin-1 | chr17 | GO:0010508 | Not Cancer Driver | No | 36 | 0.08 | 190 | 15 | 0.0333333333333333 | 0 |
| BNIP3-201 | BNIP3 | Q12983 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 | chr10 | GO:0010508 | Not Cancer Driver | No | 16 | 0.0824742268041237 | 131 | 11 | 0.056701030927835 | 0 |
| CCNY-203 | CCNY | Q8ND76 | Cyclin-Y | chr10 | GO:0010508 | Not Cancer Driver | No | 24 | 0.0703812316715542 | 94 | 5 | 0.0146627565982404 | 0 |
| CDK16-202 | CDK16 | Q00536 | Cyclin-dependent kinase 16 | chrX | GO:0010508 | Not Cancer Driver | No | 42 | 0.0846774193548387 | 140 | 21 | 0.0423387096774193 | 0 |
| DAPK1-202 | DAPK1 | P53355 | Death-associated protein kinase 1 | chr9 | GO:0010508 | Not Cancer Driver | No | 149 | 0.1041958041958042 | 116 | 12 | 0.0083916083916083 | 0 |
| DCN-201 | DCN | P07585 | Decorin | chr12 | GO:0010508 | Not Cancer Driver | No | 74 | 0.2061281337047353 | 81 | 21 | 0.0584958217270195 | 0 |
| DEPDC5-264 | DEPDC5 | O75140 | GATOR complex protein DEPDC5 | chr22 | GO:0010508 | Not Cancer Driver | No | 162 | 0.1010605115408608 | 580 | 66 | 0.0411728009981285 | 7 |
| DEPTOR-201 | DEPTOR | Q8TB45 | DEP domain-containing mTOR-interacting protein | chr8 | GO:0010508 | Not Cancer Driver | No | 42 | 0.1026894865525672 | 128 | 11 | 0.0268948655256723 | 0 |
| DHRSX-201 | DHRSX | Q8N5I4 | Dehydrogenase/reductase SDR family member on chromosome X | chrX | GO:0010508 | Not Cancer Driver | No | 34 | 0.103030303030303 | 5 | 0 | 0.0 | 0 |
| ENDOG-201 | ENDOG | Q14249 | Endonuclease G, mitochondrial | chr9 | GO:0010508 | Not Cancer Driver | No | 7 | 0.0235690235690235 | 61 | 0 | 0.0 | 0 |
| FLCN-201 | FLCN | Q8NFG4 | Folliculin | chr17 | GO:0010508 | Census, Compendium | Yes | 49 | 0.0846286701208981 | 159 | 20 | 0.0345423143350604 | 6 |
| FOXO1-201 | FOXO1 | Q12778 | Forkhead box protein O1 | chr13 | GO:0010508 | Census, Compendium | Yes | 52 | 0.0793893129770992 | 586 | 51 | 0.0778625954198473 | 0 |
| FOXO3-202 | FOXO3 | O43524 | Forkhead box protein O3 | chr6 | GO:0010508 | Census, Compendium | Yes | 54 | 0.0802377414561664 | 597 | 50 | 0.0742942050520059 | 0 |
| GSK3A-201 | GSK3A | P49840 | Glycogen synthase kinase-3 alpha | chr19 | GO:0010508 | Not Cancer Driver | No | 33 | 0.0683229813664596 | 180 | 5 | 0.010351966873706 | 0 |
| GSK3B-201 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | GO:0010508 | Not Cancer Driver | No | 34 | 0.0809523809523809 | 148 | 6 | 0.0142857142857142 | 0 |
| HMGB1-203 | HMGB1 | P09429 | High mobility group protein B1 | chr13 | GO:0010508 | Not Cancer Driver | No | 10 | 0.0465116279069767 | 202 | 7 | 0.0325581395348837 | 0 |
| IFNB1-201 | IFNB1 | P01574 | Interferon beta | chr9 | GO:0010508 | Not Cancer Driver | No | 29 | 0.1550802139037433 | 0 | 0 | 0.0 | 0 |
| IFNG-201 | IFNG | P01579 | Interferon gamma | chr12 | GO:0010508 | Not Cancer Driver | No | 34 | 0.2048192771084337 | 23 | 3 | 0.0180722891566265 | 0 |
| IRGM-202 | IRGM | A1A4Y4 | Immunity-related GTPase family M protein | chr5 | GO:0010508 | Not Cancer Driver | No | 7 | 0.0386740331491712 | 51 | 0 | 0.0 | 0 |
| KAT5-203 | KAT5 | Q92993 | Histone acetyltransferase KAT5 | chr11 | GO:0010508 | Not Cancer Driver | No | 45 | 0.087719298245614 | 174 | 16 | 0.0311890838206627 | 3 |
| LRRK2-201 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | GO:0010508 | Not Cancer Driver | No | 402 | 0.1590819153146023 | 91 | 13 | 0.0051444400474871 | 20 |
| MEFV-201 | MEFV | O15553 | Pyrin | chr16 | GO:0010508 | Not Cancer Driver | No | 152 | 0.1946222791293214 | 402 | 91 | 0.11651728553137 | 43 |
| MID2-201 | MID2 | Q9UJV3 | Probable E3 ubiquitin-protein ligase MID2 | chrX | GO:0010508 | Not Cancer Driver | No | 81 | 0.110204081632653 | 96 | 19 | 0.0258503401360544 | 1 |
| MTDH-201 | MTDH | Q86UE4 | Protein LYRIC | chr8 | GO:0010508 | Not Cancer Driver | No | 45 | 0.0773195876288659 | 518 | 44 | 0.0756013745704467 | 0 |
| NPRL2-201 | NPRL2 | Q8WTW4 | GATOR complex protein NPRL2 | chr3 | GO:0010508 | Compendium | Yes | 24 | 0.0631578947368421 | 10 | 2 | 0.0052631578947368 | 1 |
| NPRL3-211 | NPRL3 | Q12980 | GATOR complex protein NPRL3 | chr16 | GO:0010508 | Not Cancer Driver | No | 34 | 0.0597539543057996 | 160 | 18 | 0.031634446397188 | 0 |
| OPTN-202 | OPTN | Q96CV9 | Optineurin | chr10 | GO:0010508 | Not Cancer Driver | No | 47 | 0.0814558058925476 | 475 | 40 | 0.0693240901213171 | 6 |
| ORMDL3-201 | ORMDL3 | Q8N138 | ORM1-like protein 3 | chr17 | GO:0010508 | Not Cancer Driver | No | 15 | 0.0980392156862745 | 9 | 1 | 0.0065359477124183 | 0 |
| PIK3C2A-206 | PIK3C2A | O00443 | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | chr11 | GO:0010508 | Not Cancer Driver | No | 119 | 0.0705812574139976 | 351 | 24 | 0.0142348754448398 | 0 |
| PIK3CB-214 | PIK3CB | P42338 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | chr3 | GO:0010508 | Census, Compendium | Yes | 112 | 0.1046728971962616 | 42 | 3 | 0.002803738317757 | 0 |
| PIM2-201 | PIM2 | Q9P1W9 | Serine/threonine-protein kinase pim-2 | chrX | GO:0010508 | Not Cancer Driver | No | 37 | 0.1189710610932476 | 47 | 7 | 0.022508038585209 | 0 |
| PLEKHF1-201 | PLEKHF1 | Q96S99 | Pleckstrin homology domain-containing family F member 1 | chr19 | GO:0010508 | Not Cancer Driver | No | 22 | 0.078853046594982 | 65 | 6 | 0.021505376344086 | 0 |
| PLK2-201 | PLK2 | Q9NYY3 | Serine/threonine-protein kinase PLK2 | chr5 | GO:0010508 | Not Cancer Driver | No | 55 | 0.0802919708029197 | 180 | 18 | 0.0262773722627737 | 0 |
| PRKAA1-204 | PRKAA1 | Q13131 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | chr5 | GO:0010508 | Not Cancer Driver | No | 54 | 0.0966010733452593 | 124 | 13 | 0.0232558139534883 | 0 |
| PRKAA2-201 | PRKAA2 | P54646 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | chr1 | GO:0010508 | Not Cancer Driver | No | 90 | 0.1630434782608695 | 98 | 18 | 0.0326086956521739 | 0 |
| PRKD1-201 | PRKD1 | Q15139 | Serine/threonine-protein kinase D1 | chr14 | GO:0010508 | Census | Yes | 164 | 0.1798245614035087 | 190 | 31 | 0.0339912280701754 | 2 |
| RB1CC1-201 | RB1CC1 | Q8TDY2 | RB1-inducible coiled-coil protein 1 | chr8 | GO:0010508 | Not Cancer Driver | No | 150 | 0.0941028858218318 | 579 | 56 | 0.0351317440401505 | 0 |
| RFPL1-201 | RFPL1 | O75677 | Ret finger protein-like 1 | chr22 | GO:0010508 | Not Cancer Driver | No | 44 | 0.138801261829653 | 28 | 5 | 0.0157728706624605 | 0 |
| RFPL2-206 | RFPL2 | O75678 | Ret finger protein-like 2 | chr22 | GO:0010508 | Not Cancer Driver | No | 57 | 0.1507936507936507 | 73 | 11 | 0.0291005291005291 | 0 |
| RFPL3-201 | RFPL3 | O75679 | Ret finger protein-like 3 | chr22 | GO:0010508 | Not Cancer Driver | No | 62 | 0.195583596214511 | 30 | 2 | 0.0063091482649842 | 0 |
| RFPL4A-201 | RFPL4A | A6NLU0 | Ret finger protein-like 4A | chr19 | GO:0010508 | Not Cancer Driver | No | 23 | 0.0801393728222996 | 11 | 2 | 0.0069686411149825 | 0 |
| RFPL4AL1-201 | RFPL4AL1 | F8VTS6 | Ret finger protein-like 4A-like protein 1 | chr19 | GO:0010508 | Not Cancer Driver | No | 0 | 0.0 | 13 | 0 | 0.0 | 0 |
| RNF152-201 | RNF152 | Q8N8N0 | E3 ubiquitin-protein ligase RNF152 | chr18 | GO:0010508 | Not Cancer Driver | No | 57 | 0.2807881773399014 | 34 | 9 | 0.0443349753694581 | 0 |
| ROCK1-201 | ROCK1 | Q13464 | Rho-associated protein kinase 1 | chr18 | GO:0010508 | Not Cancer Driver | No | 116 | 0.0856720827178729 | 780 | 61 | 0.0450516986706056 | 0 |
| SETD2-202 | SETD2 | Q9BYW2 | Histone-lysine N-methyltransferase SETD2 | chr3 | GO:0010508 | Census, Compendium | Yes | 233 | 0.0908736349453978 | 1949 | 144 | 0.0561622464898595 | 4 |
| SH3BP4-202 | SH3BP4 | Q9P0V3 | SH3 domain-binding protein 4 | chr2 | GO:0010508 | Not Cancer Driver | No | 114 | 0.1183800623052959 | 243 | 36 | 0.0373831775700934 | 0 |
| SH3GLB1-201 | SH3GLB1 | Q9Y371 | Endophilin-B1 | chr1 | GO:0010508 | Not Cancer Driver | No | 30 | 0.0821917808219178 | 82 | 6 | 0.0164383561643835 | 0 |
| SLC35D3-201 | SLC35D3 | Q5M8T2 | Solute carrier family 35 member D3 | chr6 | GO:0010508 | Not Cancer Driver | No | 42 | 0.1009615384615384 | 89 | 13 | 0.03125 | 0 |
| SQSTM1-202 | SQSTM1 | Q13501 | Sequestosome-1 | chr5 | GO:0010508 | Not Cancer Driver | No | 41 | 0.0931818181818181 | 271 | 24 | 0.0545454545454545 | 30 |
| STK11-201 | STK11 | Q15831 | Serine/threonine-protein kinase STK11 | chr19 | GO:0010508 | Census, Compendium | Yes | 63 | 0.1454965357967667 | 135 | 12 | 0.0277136258660508 | 9 |
| SVIP-201 | SVIP | Q8NHG7 | Small VCP/p97-interacting protein | chr11 | GO:0010508 | Not Cancer Driver | No | 10 | 0.1298701298701298 | 78 | 11 | 0.1428571428571428 | 0 |
| TBK1-201 | TBK1 | Q9UHD2 | Serine/threonine-protein kinase TBK1 | chr12 | GO:0010508 | Not Cancer Driver | No | 68 | 0.093278463648834 | 42 | 4 | 0.0054869684499314 | 12 |
| TFEB-204 | TFEB | P19484 | Transcription factor EB | chr6 | GO:0010508 | Census | Yes | 46 | 0.0966386554621848 | 431 | 41 | 0.0861344537815126 | 0 |
| TICAM1-201 | TICAM1 | Q8IUC6 | TIR domain-containing adapter molecule 1 | chr19 | GO:0010508 | Not Cancer Driver | No | 75 | 0.1053370786516853 | 445 | 50 | 0.0702247191011236 | 1 |
| TLR9-201 | TLR9 | Q9NR96 | Toll-like receptor 9 | chr3 | GO:0010508 | Not Cancer Driver | No | 107 | 0.1036821705426356 | 35 | 3 | 0.002906976744186 | 0 |
| TMEM59-201 | TMEM59 | Q9BXS4 | Transmembrane protein 59 | chr1 | GO:0010508 | Not Cancer Driver | No | 25 | 0.0773993808049535 | 26 | 2 | 0.0061919504643962 | 0 |
| TP53INP1-201 | TP53INP1 | Q96A56 | Tumor protein p53-inducible nuclear protein 1 | chr8 | GO:0010508 | Not Cancer Driver | No | 21 | 0.0875 | 134 | 12 | 0.05 | 0 |
| TPCN1-201 | TPCN1 | Q9ULQ1 | Two pore channel protein 1 | chr12 | GO:0010508 | Not Cancer Driver | No | 83 | 0.1017156862745098 | 99 | 8 | 0.0098039215686274 | 0 |
| TRIM21-201 | TRIM21 | P19474 | E3 ubiquitin-protein ligase TRIM21 | chr11 | GO:0010508 | Not Cancer Driver | No | 63 | 0.1326315789473684 | 49 | 8 | 0.0168421052631578 | 0 |
| TRIM22-201 | TRIM22 | Q8IYM9 | E3 ubiquitin-protein ligase TRIM22 | chr11 | GO:0010508 | Not Cancer Driver | No | 64 | 0.1285140562248996 | 27 | 0 | 0.0 | 0 |
| TRIM23-201 | TRIM23 | P36406 | E3 ubiquitin-protein ligase TRIM23 | chr5 | GO:0010508 | Not Cancer Driver | No | 65 | 0.1132404181184669 | 39 | 2 | 0.0034843205574912 | 0 |
| TRIM32-203 | TRIM32 | Q13049 | E3 ubiquitin-protein ligase TRIM32 | chr9 | GO:0010508 | Not Cancer Driver | No | 62 | 0.0949464012251148 | 87 | 9 | 0.0137825421133231 | 3 |
| TRIM34-201 | TRIM34 | Q9BYJ4 | E3 ubiquitin-protein ligase TRIM34 | chr11 | GO:0010508 | Not Cancer Driver | No | 55 | 0.1127049180327868 | 32 | 2 | 0.0040983606557377 | 0 |
| TRIM38-201 | TRIM38 | O00635 | E3 ubiquitin-protein ligase TRIM38 | chr6 | GO:0010508 | Not Cancer Driver | No | 46 | 0.0989247311827957 | 49 | 5 | 0.010752688172043 | 0 |
| TRIM5-202 | TRIM5 | Q9C035 | Tripartite motif-containing protein 5 | chr11 | GO:0010508 | Not Cancer Driver | No | 38 | 0.0770791075050709 | 78 | 7 | 0.0141987829614604 | 0 |
| TRIM58-201 | TRIM58 | Q8NG06 | E3 ubiquitin-protein ligase TRIM58 | chr1 | GO:0010508 | Not Cancer Driver | No | 163 | 0.3353909465020576 | 84 | 32 | 0.0658436213991769 | 0 |
| TRIM6-201 | TRIM6 | Q9C030 | Tripartite motif-containing protein 6 | chr11 | GO:0010508 | Not Cancer Driver | No | 58 | 0.1188524590163934 | 48 | 12 | 0.0245901639344262 | 0 |
| TRIM65-201 | TRIM65 | Q6PJ69 | E3 ubiquitin-protein ligase TRIM65 | chr17 | GO:0010508 | Not Cancer Driver | No | 40 | 0.0773694390715667 | 128 | 11 | 0.0212765957446808 | 0 |
| TRIM68-201 | TRIM68 | Q6AZZ1 | E3 ubiquitin-protein ligase TRIM68 | chr11 | GO:0010508 | Not Cancer Driver | No | 56 | 0.1154639175257732 | 37 | 7 | 0.0144329896907216 | 0 |
| TRIM8-209 | TRIM8 | Q9BZR9 | E3 ubiquitin-protein ligase TRIM8 | chr10 | GO:0010508 | Not Cancer Driver | No | 52 | 0.0943738656987295 | 209 | 23 | 0.0417422867513611 | 0 |
| UFL1-201 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | GO:0010508 | Not Cancer Driver | No | 77 | 0.096977329974811 | 141 | 19 | 0.0239294710327455 | 0 |
| ULK1-201 | ULK1 | O75385 | Serine/threonine-protein kinase ULK1 | chr12 | GO:0010508 | Not Cancer Driver | No | 125 | 0.119047619047619 | 591 | 66 | 0.0628571428571428 | 0 |
| ULK2-202 | ULK2 | Q8IYT8 | Serine/threonine-protein kinase ULK2 | chr17 | GO:0010508 | Not Cancer Driver | No | 99 | 0.0955598455598455 | 520 | 70 | 0.0675675675675675 | 0 |
| USP20-203 | USP20 | Q9Y2K6 | Ubiquitin carboxyl-terminal hydrolase 20 | chr9 | GO:0010508 | Not Cancer Driver | No | 87 | 0.0951859956236323 | 296 | 30 | 0.0328227571115973 | 0 |
| ZC3H12A-201 | ZC3H12A | Q5D1E8 | Endoribonuclease ZC3H12A | chr1 | GO:0010508 | Not Cancer Driver | No | 77 | 0.1285475792988314 | 397 | 38 | 0.0634390651085141 | 0 |