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Total number of protein in "GO:0010629" GO term:  241

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCC2-203 ABCC2 Q92887 ATP-binding cassette sub-family C member 2 chr10 GO:0010629 Not Cancer Driver No 124 0.0802588996763754 102 16 0.0103559870550161 4
ACACB-201 ACACB O00763 Acetyl-CoA carboxylase 2 chr12 GO:0010629 Not Cancer Driver No 281 0.114320585842148 345 50 0.0203417412530512 0
ACE-202 ACE P12821 Angiotensin-converting enzyme chr17 GO:0010629 Not Cancer Driver No 152 0.116385911179173 87 5 0.0038284839203675 0
ACVR1B-201 ACVR1B P36896 Activin receptor type-1B chr12 GO:0010629 Census Yes 95 0.1881188118811881 0 0 0.0 0
ACVRL1-201 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0010629 Not Cancer Driver No 80 0.1590457256461232 60 10 0.0198807157057654 64
ADAM10-201 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 GO:0010629 Not Cancer Driver No 73 0.0975935828877005 156 18 0.0240641711229946 4
ADNP-205 ADNP Q9H2P0 Activity-dependent neuroprotector homeobox protein chr20 GO:0010629 Not Cancer Driver No 96 0.087114337568058 615 52 0.0471869328493647 0
AFF2-205 AFF2 P51816 AF4/FMR2 family member 2 chrX GO:0010629 Not Cancer Driver No 322 0.2456140350877192 1004 245 0.186880244088482 0
AKIRIN2-201 AKIRIN2 Q53H80 Akirin-2 chr6 GO:0010629 Not Cancer Driver No 19 0.0935960591133004 124 11 0.0541871921182266 0
AKT1-218 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0010629 Census, Compendium Yes 99 0.20625 158 19 0.0395833333333333 4
ANAPC2-201 ANAPC2 Q9UJX6 Anaphase-promoting complex subunit 2 chr9 GO:0010629 Not Cancer Driver No 81 0.0985401459854014 147 22 0.0267639902676399 0
ANXA7-201 ANXA7 P20073 Annexin A7 chr10 GO:0010629 Not Cancer Driver No 0 0.0 0 0 0.0 0
APLN-201 APLN Q9ULZ1 Apelin chrX GO:0010629 Not Cancer Driver No 6 0.0779220779220779 52 7 0.0909090909090909 0
APLNR-202 APLNR P35414 Apelin receptor chr11 GO:0010629 Not Cancer Driver No 76 0.2 29 7 0.0184210526315789 0
APOE-201 APOE P02649 Apolipoprotein E chr19 GO:0010629 Not Cancer Driver No 20 0.0630914826498422 124 5 0.0157728706624605 10
APP-201 APP P05067 Amyloid-beta precursor protein chr21 GO:0010629 Not Cancer Driver No 94 0.122077922077922 419 52 0.0675324675324675 12
ATOH8-201 ATOH8 Q96SQ7 Transcription factor ATOH8 chr2 GO:0010629 Not Cancer Driver No 24 0.0747663551401869 257 18 0.0560747663551401 0
ATP2B4-203 ATP2B4 P23634 Plasma membrane calcium-transporting ATPase 4 chr1 GO:0010629 Not Cancer Driver No 113 0.0937759336099585 264 20 0.0165975103734439 0
AURKA-208 AURKA O14965 Aurora kinase A chr20 GO:0010629 Not Cancer Driver No 25 0.0620347394540942 180 17 0.0421836228287841 0
AXIN1-201 AXIN1 O15169 Axin-1 chr16 GO:0010629 Census, Compendium Yes 91 0.105568445475638 623 69 0.0800464037122969 4
BAK1-201 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0010629 Not Cancer Driver No 25 0.1184834123222748 58 5 0.0236966824644549 0
BBS2-201 BBS2 Q9BXC9 Bardet-Biedl syndrome 2 protein chr16 GO:0010629 Not Cancer Driver No 60 0.0832177531206657 76 8 0.0110957004160887 20
BBS4-201 BBS4 Q96RK4 Bardet-Biedl syndrome 4 protein chr15 GO:0010629 Not Cancer Driver No 44 0.0847784200385356 111 14 0.0269749518304431 9
BMP2-201 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0010629 Not Cancer Driver No 54 0.1363636363636363 140 22 0.0555555555555555 0
BMP4-201 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0010629 Not Cancer Driver No 69 0.1691176470588235 142 20 0.0490196078431372 5
BMPR1A-201 BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0010629 Census, Compendium Yes 37 0.0695488721804511 21 0 0.0 8
BRIP1-201 BRIP1 Q9BX63 Fanconi anemia group J protein chr17 GO:0010629 Census Yes 118 0.0944755804643715 399 41 0.032826261008807 6
CCDC3-201 CCDC3 Q9BQI4 Coiled-coil domain-containing protein 3 chr10 GO:0010629 Not Cancer Driver No 36 0.1333333333333333 68 18 0.0666666666666666 0
CCL3-204 CCL3 P10147 C-C motif chemokine 3 chr17 GO:0010629 Not Cancer Driver No 13 0.1413043478260869 0 0 0.0 0
CCN2-201 CCN2 P29279 CCN family member 2 chr6 GO:0010629 Not Cancer Driver No 37 0.1060171919770773 0 0 0.0 0
CCR1-201 CCR1 P32246 C-C chemokine receptor type 1 chr3 GO:0010629 Not Cancer Driver No 47 0.1323943661971831 14 0 0.0 0
CD28-201 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0010629 Census Yes 26 0.1181818181818181 18 6 0.0272727272727272 0
CD34-201 CD34 P28906 Hematopoietic progenitor cell antigen CD34 chr1 GO:0010629 Not Cancer Driver No 48 0.1246753246753246 221 24 0.0623376623376623 0
CD36-214 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0010629 Not Cancer Driver No 48 0.1016949152542373 12 3 0.0063559322033898 3
CD3E-201 CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 GO:0010629 Not Cancer Driver No 16 0.0772946859903381 72 6 0.0289855072463768 0
CD46-205 CD46 P15529 Membrane cofactor protein chr1 GO:0010629 Not Cancer Driver No 40 0.1020408163265306 52 4 0.010204081632653 5
CDK1-203 CDK1 P06493 Cyclin-dependent kinase 1 chr10 GO:0010629 Not Cancer Driver No 26 0.0875420875420875 1 0 0.0 0
CDKN1A-201 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:0010629 Census, Compendium Yes 38 0.2317073170731707 121 25 0.1524390243902439 0
CELF1-202 CELF1 Q92879 CUGBP Elav-like family member 1 chr11 GO:0010629 Not Cancer Driver No 50 0.102880658436214 166 14 0.0288065843621399 0
CHD4-206 CHD4 Q14839 Chromodomain-helicase-DNA-binding protein 4 chr12 GO:0010629 Census, Compendium Yes 312 0.1631799163179916 978 118 0.0617154811715481 6
CHMP1A-201 CHMP1A Q9HD42 Charged multivesicular body protein 1a chr16 GO:0010629 Not Cancer Driver No 14 0.0714285714285714 111 5 0.0255102040816326 0
CILP-201 CILP O75339 Cartilage intermediate layer protein 1 chr15 GO:0010629 Not Cancer Driver No 157 0.1326013513513513 278 34 0.0287162162162162 0
CITED2-201 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0010629 Not Cancer Driver No 22 0.0814814814814814 232 19 0.0703703703703703 0
CLDN19-201 CLDN19 Q8N6F1 Claudin-19 chr1 GO:0010629 Not Cancer Driver No 21 0.09375 20 2 0.0089285714285714 3
CLDN3-201 CLDN3 O15551 Claudin-3 chr7 GO:0010629 Not Cancer Driver No 12 0.0545454545454545 0 0 0.0 0
CLDN5-204 CLDN5 O00501 Claudin-5 chr22 GO:0010629 Not Cancer Driver No 17 0.0779816513761468 0 0 0.0 0
CNOT7-201 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 GO:0010629 Not Cancer Driver No 20 0.0701754385964912 21 0 0.0 0
CNPY2-201 CNPY2 Q9Y2B0 Protein canopy homolog 2 chr12 GO:0010629 Not Cancer Driver No 22 0.1208791208791208 24 5 0.0274725274725274 0
CPNE1-204 CPNE1 Q99829 Copine-1 chr20 GO:0010629 Not Cancer Driver No 59 0.1098696461824953 81 9 0.0167597765363128 0
CREB3L1-206 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:0010629 Census Yes 54 0.1040462427745664 373 39 0.0751445086705202 0
CRH-201 CRH P06850 Corticoliberin chr8 GO:0010629 Not Cancer Driver No 9 0.0459183673469387 131 9 0.0459183673469387 0
CRKL-201 CRKL P46109 Crk-like protein chr22 GO:0010629 Not Cancer Driver No 24 0.0792079207920792 160 17 0.0561056105610561 0
CRYAB-217 CRYAB P02511 Alpha-crystallin B chain chr11 GO:0010629 Not Cancer Driver No 17 0.0971428571428571 59 7 0.04 5
CTNNB1-201 CTNNB1 P35222 Catenin beta-1 chr3 GO:0010629 Census, Compendium Yes 363 0.4647887323943662 288 291 0.3725992317541613 11
CXCL8-201 CXCL8 P10145 Interleukin-8 chr4 GO:0010629 Not Cancer Driver No 12 0.1212121212121212 0 0 0.0 0
DAXX-202 DAXX Q9UER7 Death domain-associated protein 6 chr6 GO:0010629 Census, Compendium Yes 79 0.1067567567567567 549 57 0.077027027027027 0
DDRGK1-201 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 GO:0010629 Not Cancer Driver No 26 0.0828025477707006 181 19 0.0605095541401273 0
DDX3X-244 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0010629 Census, Compendium Yes 91 0.1374622356495468 302 32 0.0483383685800604 18
DDX3Y-201 DDX3Y O15523 ATP-dependent RNA helicase DDX3Y chrY GO:0010629 Not Cancer Driver No 27 0.0409090909090909 289 16 0.0242424242424242 0
DGKQ-201 DGKQ P52824 Diacylglycerol kinase theta chr4 GO:0010629 Not Cancer Driver No 53 0.0562632696390658 268 11 0.0116772823779193 0
DICER1-201 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 GO:0010629 Census, Compendium Yes 183 0.0952133194588969 363 31 0.0161290322580645 4
DIP2A-202 DIP2A Q14689 Disco-interacting protein 2 homolog A chr21 GO:0010629 Not Cancer Driver No 139 0.0884786760025461 399 36 0.022915340547422 0
DLL4-201 DLL4 Q9NR61 Delta-like protein 4 chr15 GO:0010629 Not Cancer Driver No 64 0.0934306569343065 73 11 0.0160583941605839 6
DNMT1-201 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 GO:0010629 Not Cancer Driver No 135 0.083539603960396 706 52 0.0321782178217821 4
EDN1-201 EDN1 P05305 Endothelin-1 chr6 GO:0010629 Not Cancer Driver No 27 0.1273584905660377 98 16 0.0754716981132075 3
EMILIN1-201 EMILIN1 Q9Y6C2 EMILIN-1 chr2 GO:0010629 Not Cancer Driver No 89 0.0875984251968503 671 50 0.0492125984251968 1
ENG-202 ENG P17813 Endoglin chr9 GO:0010629 Not Cancer Driver No 47 0.0714285714285714 114 11 0.0167173252279635 29
ENST00000647725 FOXP1 Q9H334 Forkhead box protein P1 chr3 GO:0010629 Census, Compendium Yes 83 0.1225997045790251 449 54 0.0797636632200886 3
ERP29-201 ERP29 P30040 Endoplasmic reticulum resident protein 29 chr12 GO:0010629 Not Cancer Driver No 24 0.0919540229885057 34 4 0.0153256704980842 0
ESR1-201 ESR1 P03372 Estrogen receptor chr6 GO:0010629 Census, Compendium Yes 92 0.1546218487394958 198 19 0.0319327731092436 2
FBXW7-201 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:0010629 Census, Compendium Yes 289 0.4087694483734088 232 15 0.0212164073550212 17
FERMT1-201 FERMT1 Q9BQL6 Fermitin family homolog 1 chr20 GO:0010629 Not Cancer Driver No 75 0.1107828655834564 65 6 0.0088626292466765 2
FGF19-201 FGF19 O95750 Fibroblast growth factor 19 chr11 GO:0010629 Not Cancer Driver No 18 0.0833333333333333 36 5 0.0231481481481481 0
FGF2-201 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0010629 Not Cancer Driver No 17 0.0590277777777777 183 5 0.0173611111111111 0
FLCN-201 FLCN Q8NFG4 Folliculin chr17 GO:0010629 Census, Compendium Yes 49 0.0846286701208981 159 20 0.0345423143350604 6
FLOT2-202 FLOT2 Q14254 Flotillin-2 chr17 GO:0010629 Not Cancer Driver No 52 0.1214953271028037 20 2 0.0046728971962616 0
FOXP1-254 FOXP1 Q9H334 Forkhead box protein P1 chr3 GO:0010629 Census, Compendium Yes 83 0.1225997045790251 449 54 0.0797636632200886 3
FYN-202 FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0010629 Not Cancer Driver No 64 0.1191806331471136 71 11 0.0204841713221601 0
GATA2-201 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:0010629 Census, Compendium Yes 60 0.125 372 43 0.0895833333333333 6
GATA5-201 GATA5 Q9BWX5 Transcription factor GATA-5 chr20 GO:0010629 Not Cancer Driver No 26 0.0654911838790932 268 16 0.0403022670025188 9
GGNBP2-212 GGNBP2 Q9H3C7 Gametogenetin-binding protein 2 chr17 GO:0010629 Not Cancer Driver No 73 0.1047345767575322 156 11 0.0157819225251076 0
GJA1-201 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0010629 Not Cancer Driver No 62 0.1623036649214659 111 20 0.0523560209424083 43
GPER1-202 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0010629 Not Cancer Driver No 47 0.1253333333333333 13 4 0.0106666666666666 0
GSK3B-201 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0010629 Not Cancer Driver No 34 0.0809523809523809 148 6 0.0142857142857142 0
HAND2-201 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0010629 Not Cancer Driver No 39 0.1797235023041474 124 24 0.1105990783410138 0
HAVCR2-201 HAVCR2 Q8TDQ0 Hepatitis A virus cellular receptor 2 chr5 GO:0010629 Not Cancer Driver No 45 0.1495016611295681 17 1 0.0033222591362126 3
HDAC1-201 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:0010629 Not Cancer Driver No 30 0.0622406639004149 135 5 0.0103734439834024 0
HES1-201 HES1 Q14469 Transcription factor HES-1 chr3 GO:0010629 Not Cancer Driver No 35 0.125 227 30 0.1071428571428571 0
HEY2-201 HEY2 Q9UBP5 Hairy/enhancer-of-split related with YRPW motif protein 2 chr6 GO:0010629 Not Cancer Driver No 50 0.1483679525222551 181 21 0.0623145400593471 0
HEYL-201 HEYL Q9NQ87 Hairy/enhancer-of-split related with YRPW motif-like protein chr1 GO:0010629 Not Cancer Driver No 29 0.0884146341463414 199 13 0.0396341463414634 0
HIF1A-202 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0010629 Census Yes 54 0.0653753026634382 436 28 0.0338983050847457 0
HINFP-201 HINFP Q9BQA5 Histone H4 transcription factor chr11 GO:0010629 Not Cancer Driver No 49 0.0947775628626692 156 20 0.0386847195357833 0
HMGB2-201 HMGB2 P26583 High mobility group protein B2 chr4 GO:0010629 Not Cancer Driver No 26 0.124401913875598 207 26 0.124401913875598 0
HNRNPD-201 HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0010629 Not Cancer Driver No 28 0.0788732394366197 206 12 0.0338028169014084 0
HRAS-201 HRAS P01112 GTPase HRas chr11 GO:0010629 Census, Compendium Yes 129 0.6825396825396826 16 2 0.0105820105820105 10
HSF1-204 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0010629 Not Cancer Driver No 49 0.0926275992438563 336 30 0.0567107750472589 0
ID2-203 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0010629 Not Cancer Driver No 13 0.0970149253731343 52 6 0.044776119402985 0
ID3-201 ID3 Q02535 DNA-binding protein inhibitor ID-3 chr1 GO:0010629 Census, Compendium Yes 10 0.0840336134453781 34 3 0.0252100840336134 0
IFNA2-201 IFNA2 P01563 Interferon alpha-2 chr9 GO:0010629 Not Cancer Driver No 24 0.1276595744680851 2 0 0.0 0
IFNG-201 IFNG P01579 Interferon gamma chr12 GO:0010629 Not Cancer Driver No 34 0.2048192771084337 23 3 0.0180722891566265 0
IGF1-201 IGF1 P05019 Insulin-like growth factor I chr12 GO:0010629 Not Cancer Driver No 30 0.1538461538461538 87 18 0.0923076923076923 0
INPPL1-201 INPPL1 O15357 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 chr11 GO:0010629 Not Cancer Driver No 146 0.1160572337042925 567 66 0.0524642289348171 4
INS-202 INS P01308 Insulin chr11 GO:0010629 Not Cancer Driver No 7 0.0636363636363636 5 1 0.009090909090909 19
IQGAP3-201 IQGAP3 Q86VI3 Ras GTPase-activating-like protein IQGAP3 chr1 GO:0010629 Not Cancer Driver No 169 0.1036174126302881 259 26 0.0159411404046597 0
ITGB8-201 ITGB8 P26012 Integrin beta-8 chr7 GO:0010629 Not Cancer Driver No 89 0.1157347204161248 26 2 0.0026007802340702 0
KDM4A-201 KDM4A O75164 Lysine-specific demethylase 4A chr1 GO:0010629 Not Cancer Driver No 90 0.0845864661654135 341 35 0.0328947368421052 0
KDR-201 KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0010629 Census, Compendium Yes 276 0.2035398230088495 276 40 0.0294985250737463 2
KLF4-201 KLF4 O43474 Krueppel-like factor 4 chr9 GO:0010629 Census, Compendium Yes 41 0.0855949895615866 417 25 0.0521920668058455 0
KPNA7-201 KPNA7 A9QM74 Importin subunit alpha-8 chr7 GO:0010629 Not Cancer Driver No 19 0.0368217054263565 66 3 0.005813953488372 0
LDLR-208 LDLR P01130 Low-density lipoprotein receptor chr19 GO:0010629 Not Cancer Driver No 94 0.1093023255813953 63 3 0.0034883720930232 87
LGALS9-203 LGALS9 O00182 Galectin-9 chr17 GO:0010629 Not Cancer Driver No 46 0.1295774647887324 65 13 0.0366197183098591 0
LGMN-201 LGMN Q99538 Legumain chr14 GO:0010629 Not Cancer Driver No 40 0.092378752886836 112 11 0.0254041570438799 0
LRP1-201 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 GO:0010629 Not Cancer Driver No 512 0.1126760563380281 319 38 0.008362676056338 1
LRP3-201 LRP3 O75074 Low-density lipoprotein receptor-related protein 3 chr19 GO:0010629 Not Cancer Driver No 57 0.074025974025974 214 12 0.0155844155844155 0
MAP3K7-204 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0010629 Not Cancer Driver No 74 0.1221122112211221 333 42 0.0693069306930693 6
MAPT-212 MAPT P10636 Microtubule-associated protein tau chr17 GO:0010629 Not Cancer Driver No 100 0.1319261213720316 750 99 0.1306068601583113 17
MARK1-201 MARK1 Q9P0L2 Serine/threonine-protein kinase MARK1 chr1 GO:0010629 Not Cancer Driver No 129 0.1622641509433962 454 81 0.1018867924528302 0
MBD1-201 MBD1 Q9UIS9 Methyl-CpG-binding domain protein 1 chr18 GO:0010629 Not Cancer Driver No 77 0.1272727272727272 323 30 0.0495867768595041 0
MECP2-201 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0010629 Not Cancer Driver No 44 0.0905349794238683 482 43 0.088477366255144 32
MEF2C-209 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0010629 Not Cancer Driver No 54 0.1141649048625792 408 51 0.1078224101479915 2
MIF-201 MIF P14174 Macrophage migration inhibitory factor chr22 GO:0010629 Not Cancer Driver No 4 0.0347826086956521 0 0 0.0 0
MKKS-201 MKKS Q9NPJ1 Molecular chaperone MKKS chr20 GO:0010629 Not Cancer Driver No 35 0.0614035087719298 7 0 0.0 22
MSR1-201 MSR1 P21757 Macrophage scavenger receptor types I and II chr8 GO:0010629 Not Cancer Driver No 136 0.3015521064301552 244 90 0.1995565410199556 0
MSX1-201 MSX1 P28360 Homeobox protein MSX-1 chr4 GO:0010629 Not Cancer Driver No 32 0.1056105610561056 199 12 0.0396039603960396 7
MYADM-204 MYADM Q96S97 Myeloid-associated differentiation marker chr19 GO:0010629 Not Cancer Driver No 50 0.15527950310559 0 0 0.0 0
MYCN-201 MYCN P04198 N-myc proto-oncogene protein chr2 GO:0010629 Census, Compendium Yes 65 0.1400862068965517 415 59 0.1271551724137931 2
NDFIP1-201 NDFIP1 Q9BT67 NEDD4 family-interacting protein 1 chr5 GO:0010629 Not Cancer Driver No 17 0.0769230769230769 45 3 0.0135746606334841 0
NDFIP2-201 NDFIP2 Q9NV92 NEDD4 family-interacting protein 2 chr13 GO:0010629 Not Cancer Driver No 21 0.0625 198 11 0.0327380952380952 0
NFKB1-205 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0010629 Not Cancer Driver No 62 0.0640495867768595 345 30 0.03099173553719 0
NKX3-1-201 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0010629 Not Cancer Driver No 26 0.1111111111111111 175 12 0.0512820512820512 0
NOCT-201 NOCT Q9UK39 Nocturnin chr4 GO:0010629 Not Cancer Driver No 22 0.0510440835266821 90 2 0.0046403712296983 0
NOG-201 NOG Q13253 Noggin chr17 GO:0010629 Not Cancer Driver No 15 0.0646551724137931 87 5 0.021551724137931 17
NOS2-201 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0010629 Not Cancer Driver No 147 0.1274934952298352 201 26 0.0225498699045967 0
NOTCH1-204 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0010629 Census, Compendium Yes 312 0.1221135029354207 690 71 0.0277886497064579 3
NOTCH2-201 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0010629 Census, Compendium Yes 191 0.0772966410360178 631 61 0.0246863617968433 1
NR0B2-201 NR0B2 Q15466 Nuclear receptor subfamily 0 group B member 2 chr1 GO:0010629 Not Cancer Driver No 30 0.1167315175097276 10 2 0.0077821011673151 0
NTS-201 NTS P30990 Neurotensin/neuromedin N chr12 GO:0010629 Not Cancer Driver No 15 0.088235294117647 23 2 0.0117647058823529 0
OCLN-202 OCLN Q16625 Occludin chr5 GO:0010629 Not Cancer Driver No 44 0.0842911877394636 244 18 0.0344827586206896 1
OLFM1-204 OLFM1 Q99784 Noelin chr9 GO:0010629 Not Cancer Driver No 67 0.1381443298969072 84 11 0.022680412371134 0
OPRD1-201 OPRD1 P41143 Delta-type opioid receptor chr1 GO:0010629 Not Cancer Driver No 53 0.1424731182795699 30 2 0.0053763440860215 0
OVOL2-201 OVOL2 Q9BRP0 Transcription factor Ovo-like 2 chr20 GO:0010629 Not Cancer Driver No 28 0.1018181818181818 141 5 0.0181818181818181 0
PARK7-201 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0010629 Not Cancer Driver No 8 0.0423280423280423 30 0 0.0 6
PARP10-201 PARP10 Q53GL7 Protein mono-ADP-ribosyltransferase PARP10 chr8 GO:0010629 Not Cancer Driver No 87 0.0848780487804878 549 48 0.0468292682926829 0
PARP14-202 PARP14 Q460N5 Protein mono-ADP-ribosyltransferase PARP14 chr3 GO:0010629 Not Cancer Driver No 154 0.0855080510827318 301 42 0.0233203775680177 0
PARP15-202 PARP15 Q460N3 Protein mono-ADP-ribosyltransferase PARP15 chr3 GO:0010629 Not Cancer Driver No 60 0.0884955752212389 147 18 0.0265486725663716 0
PARP9-201 PARP9 Q8IXQ6 Protein mono-ADP-ribosyltransferase PARP9 chr3 GO:0010629 Not Cancer Driver No 85 0.0995316159250585 45 3 0.0035128805620608 0
PAWR-201 PAWR Q96IZ0 PRKC apoptosis WT1 regulator protein chr12 GO:0010629 Not Cancer Driver No 23 0.0676470588235294 328 22 0.0647058823529411 0
PC-203 PC P11498 Pyruvate carboxylase, mitochondrial chr11 GO:0010629 Not Cancer Driver No 144 0.1222410865874363 172 20 0.0169779286926994 9
PDCD10-201 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 GO:0010629 Not Cancer Driver No 25 0.1179245283018868 25 3 0.0141509433962264 0
PDGFB-201 PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0010629 Census Yes 30 0.1244813278008298 99 16 0.0663900414937759 2
PGR-202 PGR P06401 Progesterone receptor chr11 GO:0010629 Not Cancer Driver No 136 0.1457663451232583 482 54 0.0578778135048231 0
PIAS3-203 PIAS3 Q9Y6X2 E3 SUMO-protein ligase PIAS3 chr1 GO:0010629 Not Cancer Driver No 51 0.0812101910828025 266 23 0.036624203821656 0
PICALM-202 PICALM Q13492 Phosphatidylinositol-binding clathrin assembly protein chr11 GO:0010629 Census Yes 64 0.0981595092024539 320 31 0.0475460122699386 0
PIK3CA-201 PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0010629 Census, Compendium Yes 1425 1.3342696629213484 38 9 0.0084269662921348 44
PINK1-201 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0010629 Not Cancer Driver No 46 0.0791738382099827 99 8 0.0137693631669535 24
PLA2G3-201 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0010629 Not Cancer Driver No 70 0.137524557956778 177 26 0.0510805500982318 0
PLAG1-201 PLAG1 Q6DJT9 Zinc finger protein PLAG1 chr8 GO:0010629 Census, Compendium Yes 77 0.154 209 34 0.068 0
POU3F2-201 POU3F2 P20265 POU domain, class 3, transcription factor 2 chr6 GO:0010629 Not Cancer Driver No 42 0.0948081264108352 361 31 0.0699774266365688 0
POU4F1-201 POU4F1 Q01851 POU domain, class 4, transcription factor 1 chr13 GO:0010629 Not Cancer Driver No 33 0.0787589498806682 274 20 0.0477326968973747 1
PPARG-201 PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0010629 Census Yes 60 0.1188118811881188 44 3 0.0059405940594059 3
PPP2CB-201 PPP2CB P62714 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform chr8 GO:0010629 Not Cancer Driver No 27 0.087378640776699 12 0 0.0 0
PPP3CA-203 PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0010629 Compendium Yes 63 0.1209213051823416 140 24 0.0460652591170825 7
PRDM1-203 PRDM1 O75626 PR domain zinc finger protein 1 chr6 GO:0010629 Census, Compendium Yes 122 0.1478787878787879 339 56 0.0678787878787878 0
PRKAA1-204 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0010629 Not Cancer Driver No 54 0.0966010733452593 124 13 0.0232558139534883 0
PRKAA2-201 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 GO:0010629 Not Cancer Driver No 90 0.1630434782608695 98 18 0.0326086956521739 0
PRKAR1A-216 PRKAR1A P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit chr17 GO:0010629 Census, Compendium Yes 26 0.0682414698162729 66 5 0.0131233595800524 15
PRKN-206 PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0010629 Not Cancer Driver No 96 0.2064516129032258 78 14 0.0301075268817204 30
PSEN1-201 PSEN1 P49768 Presenilin-1 chr14 GO:0010629 Not Cancer Driver No 43 0.0920770877944325 134 18 0.038543897216274 69
PTH-201 PTH P01270 Parathyroid hormone chr11 GO:0010629 Not Cancer Driver No 17 0.1478260869565217 61 10 0.0869565217391304 2
PTPN22-201 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0010629 Not Cancer Driver No 107 0.1325898389095415 344 44 0.0545229244114002 4
PTRH2-201 PTRH2 Q9Y3E5 Peptidyl-tRNA hydrolase 2, mitochondrial chr17 GO:0010629 Not Cancer Driver No 7 0.0391061452513966 19 1 0.0055865921787709 1
RACK1-227 RACK1 P63244 Small ribosomal subunit protein RACK1 chr5 GO:0010629 Not Cancer Driver No 27 0.085173501577287 13 0 0.0 0
RB1-201 RB1 P06400 Retinoblastoma-associated protein chr13 GO:0010629 Census, Compendium Yes 89 0.0959051724137931 282 26 0.0280172413793103 21
RBL1-202 RBL1 P28749 Retinoblastoma-like protein 1 chr20 GO:0010629 Not Cancer Driver No 102 0.095505617977528 335 29 0.0271535580524344 0
RBL2-201 RBL2 Q08999 Retinoblastoma-like protein 2 chr16 GO:0010629 Not Cancer Driver No 78 0.0684811237928007 506 38 0.0333625987708516 0
RBMS3-203 RBMS3 Q6XE24 RNA-binding motif, single-stranded-interacting protein 3 chr3 GO:0010629 Not Cancer Driver No 63 0.1441647597254004 280 42 0.0961098398169336 0
RCOR1-201 RCOR1 Q9UKL0 REST corepressor 1 chr14 GO:0010629 Not Cancer Driver No 31 0.0639175257731958 325 17 0.0350515463917525 0
REL-201 REL Q04864 Proto-oncogene c-Rel chr2 GO:0010629 Census Yes 53 0.08562197092084 365 35 0.0565428109854604 0
REST-201 REST Q13127 RE1-silencing transcription factor chr4 GO:0010629 Not Cancer Driver No 86 0.0783956244302643 872 68 0.0619872379216043 4
RNASEH2B-201 RNASEH2B Q5TBB1 Ribonuclease H2 subunit B chr13 GO:0010629 Not Cancer Driver No 24 0.0769230769230769 84 8 0.0256410256410256 15
ROBO1-202 ROBO1 Q9Y6N7 Roundabout homolog 1 chr3 GO:0010629 Not Cancer Driver No 245 0.1483949121744397 1125 158 0.0956995760145366 0
ROCK2-202 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0010629 Not Cancer Driver No 110 0.0792507204610951 734 61 0.0439481268011527 0
SERPINF1-201 SERPINF1 P36955 Pigment epithelium-derived factor chr17 GO:0010629 Not Cancer Driver No 37 0.0885167464114832 57 5 0.0119617224880382 0
SETDB1-201 SETDB1 Q15047 Histone-lysine N-methyltransferase SETDB1 chr1 GO:0010629 Census, Compendium Yes 133 0.1030209140201394 598 62 0.0480247869868319 0
SETDB2-202 SETDB2 Q96T68 Histone-lysine N-methyltransferase SETDB2 chr13 GO:0010629 Not Cancer Driver No 51 0.0709318497913769 255 20 0.0278164116828929 0
SFMBT2-204 SFMBT2 Q5VUG0 Scm-like with four MBT domains protein 2 chr10 GO:0010629 Compendium Yes 172 0.192393736017897 241 59 0.0659955257270693 0
SFRP1-201 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0010629 Not Cancer Driver No 31 0.0987261146496815 39 4 0.0127388535031847 0
SFRP2-201 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0010629 Not Cancer Driver No 37 0.1254237288135593 1 0 0.0 0
SH3GL2-201 SH3GL2 Q99962 Endophilin-A1 chr9 GO:0010629 Not Cancer Driver No 58 0.1647727272727272 215 36 0.1022727272727272 0
SHH-201 SHH Q15465 Sonic hedgehog protein chr7 GO:0010629 Not Cancer Driver No 36 0.0779220779220779 139 11 0.0238095238095238 69
SIRT1-201 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0010629 Not Cancer Driver No 43 0.0575635876840696 435 19 0.0254350736278447 0
SLC24A3-201 SLC24A3 Q9HC58 Sodium/potassium/calcium exchanger 3 chr20 GO:0010629 Not Cancer Driver No 92 0.1428571428571428 120 37 0.0574534161490683 0
SLC2A10-201 SLC2A10 O95528 Solute carrier family 2, facilitated glucose transporter member 10 chr20 GO:0010629 Not Cancer Driver No 79 0.1460258780036968 72 10 0.0184842883548983 8
SLC35C2-204 SLC35C2 Q9NQQ7 Solute carrier family 35 member C2 chr20 GO:0010629 Not Cancer Driver No 37 0.1013698630136986 15 2 0.0054794520547945 0
SLC7A5-201 SLC7A5 Q01650 Large neutral amino acids transporter small subunit 1 chr16 GO:0010629 Not Cancer Driver No 48 0.0946745562130177 35 0 0.0 0
SLIT3-205 SLIT3 O75094 Slit homolog 3 protein chr5 GO:0010629 Not Cancer Driver No 292 0.1917268548916612 39 9 0.0059093893630991 0
SMAD3-201 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0010629 Census, Compendium Yes 80 0.188235294117647 113 15 0.0352941176470588 5
SMAD5-211 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 GO:0010629 Not Cancer Driver No 25 0.053763440860215 172 6 0.0129032258064516 0
SMCR8-201 SMCR8 Q8TEV9 Guanine nucleotide exchange protein SMCR8 chr17 GO:0010629 Not Cancer Driver No 76 0.0811099252934898 357 30 0.032017075773746 0
SMO-201 SMO Q99835 Protein smoothened chr7 GO:0010629 Census, Compendium Yes 88 0.1118170266836086 242 20 0.025412960609911 1
SNX12-202 SNX12 Q9UMY4 Sorting nexin-12 chrX GO:0010629 Not Cancer Driver No 17 0.1049382716049382 28 3 0.0185185185185185 0
SOX11-201 SOX11 P35716 Transcription factor SOX-11 chr2 GO:0010629 Not Cancer Driver No 54 0.1224489795918367 370 47 0.1065759637188208 23
SOX9-201 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0010629 Compendium Yes 69 0.1355599214145383 497 66 0.1296660117878192 13
SPI1-202 SPI1 P17947 Transcription factor PU.1 chr11 GO:0010629 Not Cancer Driver No 38 0.1407407407407407 187 28 0.1037037037037037 2
SRC-204 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0010629 Census Yes 40 0.0746268656716417 130 10 0.0186567164179104 1
STAT3-201 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0010629 Census, Compendium Yes 93 0.1207792207792207 152 16 0.0207792207792207 15
STC2-201 STC2 O76061 Stanniocalcin-2 chr5 GO:0010629 Not Cancer Driver No 60 0.1986754966887417 112 28 0.0927152317880794 0
STOX1-201 STOX1 Q6ZVD7 Storkhead-box protein 1 chr10 GO:0010629 Not Cancer Driver No 79 0.0798786653185035 660 54 0.0546006066734074 2
TAF1-204 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0010629 Not Cancer Driver No 278 0.1484249866524292 1174 156 0.0832888414308595 5
TARDBP-201 TARDBP Q13148 TAR DNA-binding protein 43 chr1 GO:0010629 Not Cancer Driver No 36 0.0869565217391304 202 12 0.0289855072463768 21
TBK1-201 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 GO:0010629 Not Cancer Driver No 68 0.093278463648834 42 4 0.0054869684499314 12
TCEAL1-202 TCEAL1 Q15170 Transcription elongation factor A protein-like 1 chrX GO:0010629 Not Cancer Driver No 13 0.0817610062893081 147 13 0.0817610062893081 1
TERF2-201 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 GO:0010629 Not Cancer Driver No 26 0.047970479704797 361 15 0.0276752767527675 0
TERT-201 TERT O14746 Telomerase reverse transcriptase chr5 GO:0010629 Census Yes 86 0.0759717314487632 213 11 0.0097173144876325 32
TFAP4-201 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:0010629 Compendium Yes 49 0.1449704142011834 287 41 0.1213017751479289 0
TGFB1-201 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0010629 Not Cancer Driver No 30 0.0769230769230769 44 3 0.0076923076923076 8
TGFB2-202 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0010629 Not Cancer Driver No 44 0.1062801932367149 47 5 0.0120772946859903 4
TIPARP-201 TIPARP Q7Z3E1 Protein mono-ADP-ribosyltransferase TIPARP chr3 GO:0010629 Not Cancer Driver No 44 0.0669710806697108 202 16 0.0243531202435312 0
TLE5-202 TLE5 Q08117 TLE family member 5 chr19 GO:0010629 Not Cancer Driver No 14 0.0710659898477157 77 8 0.0406091370558375 0
TMF1-201 TMF1 P82094 TATA element modulatory factor chr3 GO:0010629 Not Cancer Driver No 76 0.0695333943275388 950 70 0.0640439158279963 0
TNF-208 TNF P01375 Tumor necrosis factor chr6 GO:0010629 Not Cancer Driver No 22 0.0944206008583691 45 2 0.0085836909871244 0
TP53INP1-201 TP53INP1 Q96A56 Tumor protein p53-inducible nuclear protein 1 chr8 GO:0010629 Not Cancer Driver No 21 0.0875 134 12 0.05 0
TRIM6-201 TRIM6 Q9C030 Tripartite motif-containing protein 6 chr11 GO:0010629 Not Cancer Driver No 58 0.1188524590163934 48 12 0.0245901639344262 0
TTBK1-201 TTBK1 Q5TCY1 Tau-tubulin kinase 1 chr6 GO:0010629 Not Cancer Driver No 151 0.1143073429220287 1047 114 0.0862982588947766 0
UCN-201 UCN P55089 Urocortin chr2 GO:0010629 Not Cancer Driver No 7 0.0564516129032258 61 4 0.032258064516129 0
UPK3B-201 UPK3B Q9BT76 Uroplakin-3b chr7 GO:0010629 Not Cancer Driver No 21 0.065625 186 14 0.04375 0
VEGFA-226 VEGFA P15692 Vascular endothelial growth factor A, long form chr6 GO:0010629 Not Cancer Driver No 24 0.060759493670886 215 9 0.0227848101265822 0
VHL-201 VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 GO:0010629 Census, Compendium Yes 85 0.3990610328638497 117 15 0.0704225352112676 84
VPS35-201 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 GO:0010629 Not Cancer Driver No 55 0.0690954773869346 99 7 0.0087939698492462 1
WNT4-201 WNT4 P56705 Protein Wnt-4 chr1 GO:0010629 Not Cancer Driver No 25 0.0712250712250712 39 2 0.0056980056980056 5
WWP2-202 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 GO:0010629 Not Cancer Driver No 87 0.1 423 46 0.0528735632183908 0
XDH-201 XDH P47989 Xanthine dehydrogenase/oxidase chr2 GO:0010629 Not Cancer Driver No 227 0.1702925731432858 136 20 0.0150037509377344 1
YAP1-201 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0010629 Not Cancer Driver No 41 0.0813492063492063 491 41 0.0813492063492063 0
YY1-201 YY1 P25490 Transcriptional repressor protein YY1 chr14 GO:0010629 Not Cancer Driver No 29 0.0700483091787439 337 21 0.0507246376811594 2
ZBTB20-220 ZBTB20 Q9HC78 Zinc finger and BTB domain-containing protein 20 chr3 GO:0010629 Compendium Yes 135 0.1821862348178137 433 66 0.0890688259109311 4
ZBTB7B-205 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0010629 Compendium Yes 100 0.1855287569573283 355 65 0.1205936920222634 0
ZC3H12A-201 ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0010629 Not Cancer Driver No 77 0.1285475792988314 397 38 0.0634390651085141 0
ZNF148-201 ZNF148 Q9UQR1 Zinc finger protein 148 chr3 GO:0010629 Compendium Yes 84 0.105793450881612 601 59 0.0743073047858942 0
ZNF281-203 ZNF281 Q9Y2X9 Zinc finger protein 281 chr1 GO:0010629 Not Cancer Driver No 62 0.0692737430167597 710 44 0.0491620111731843 0
ZNF410-211 ZNF410 Q86VK4 Zinc finger protein 410 chr14 GO:0010629 Not Cancer Driver No 34 0.0711297071129707 309 17 0.0355648535564853 0
ZNF503-201 ZNF503 Q96F45 Zinc finger protein 503 chr10 GO:0010629 Not Cancer Driver No 27 0.0417956656346749 447 16 0.0247678018575851 0