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Total number of protein in "GO:0016241" GO term:  55

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ATG14-201 ATG14 Q6ZNE5 Beclin 1-associated autophagy-related key regulator chr14 GO:0016241 Not Cancer Driver No 43 0.0873983739837398 209 23 0.0467479674796747 0
ATP13A2-201 ATP13A2 Q9NQ11 Polyamine-transporting ATPase 13A2 chr1 GO:0016241 Not Cancer Driver No 125 0.1059322033898305 121 9 0.0076271186440677 9
ATP6V0A1-202 ATP6V0A1 Q93050 V-type proton ATPase 116 kDa subunit a 1 chr17 GO:0016241 Not Cancer Driver No 73 0.087216248506571 86 12 0.014336917562724 3
ATP6V0A2-201 ATP6V0A2 Q9Y487 V-type proton ATPase 116 kDa subunit a 2 chr12 GO:0016241 Not Cancer Driver No 65 0.0759345794392523 36 5 0.0058411214953271 0
ATP6V0B-205 ATP6V0B Q99437 V-type proton ATPase 21 kDa proteolipid subunit c'' chr1 GO:0016241 Not Cancer Driver No 18 0.0878048780487804 0 0 0.0 0
ATP6V0C-201 ATP6V0C P27449 V-type proton ATPase 16 kDa proteolipid subunit c chr16 GO:0016241 Not Cancer Driver No 10 0.064516129032258 1 0 0.0 0
ATP6V0D1-201 ATP6V0D1 P61421 V-type proton ATPase subunit d 1 chr16 GO:0016241 Not Cancer Driver No 28 0.0797720797720797 0 0 0.0 0
ATP6V0D2-201 ATP6V0D2 Q8N8Y2 V-type proton ATPase subunit d 2 chr8 GO:0016241 Not Cancer Driver No 63 0.18 0 0 0.0 0
ATP6V0E1-203 ATP6V0E1 O15342 V-type proton ATPase subunit e 1 chr5 GO:0016241 Not Cancer Driver No 6 0.074074074074074 0 0 0.0 0
ATP6V0E2-202 ATP6V0E2 Q8NHE4 V-type proton ATPase subunit e 2 chr7 GO:0016241 Not Cancer Driver No 1 0.0123456790123456 0 0 0.0 0
ATP6V1A-201 ATP6V1A P38606 V-type proton ATPase catalytic subunit A chr3 GO:0016241 Not Cancer Driver No 65 0.1053484602917342 31 0 0.0 4
ATP6V1B1-201 ATP6V1B1 P15313 V-type proton ATPase subunit B, kidney isoform chr2 GO:0016241 Not Cancer Driver No 60 0.1169590643274853 67 7 0.0136452241715399 9
ATP6V1B2-201 ATP6V1B2 P21281 V-type proton ATPase subunit B, brain isoform chr8 GO:0016241 Not Cancer Driver No 38 0.0743639921722113 49 3 0.0058708414872798 1
ATP6V1C1-202 ATP6V1C1 P21283 V-type proton ATPase subunit C 1 chr8 GO:0016241 Not Cancer Driver No 41 0.1073298429319371 17 2 0.0052356020942408 0
ATP6V1C2-201 ATP6V1C2 Q8NEY4 V-type proton ATPase subunit C 2 chr2 GO:0016241 Not Cancer Driver No 45 0.1053864168618267 47 7 0.0163934426229508 0
ATP6V1D-201 ATP6V1D Q9Y5K8 V-type proton ATPase subunit D chr14 GO:0016241 Not Cancer Driver No 22 0.0890688259109311 14 1 0.0040485829959514 0
ATP6V1E1-201 ATP6V1E1 P36543 V-type proton ATPase subunit E 1 chr22 GO:0016241 Not Cancer Driver No 18 0.079646017699115 28 2 0.0088495575221238 2
ATP6V1E2-204 ATP6V1E2 Q96A05 V-type proton ATPase subunit E 2 chr2 GO:0016241 Not Cancer Driver No 28 0.1238938053097345 12 2 0.0088495575221238 0
ATP6V1G1-201 ATP6V1G1 O75348 V-type proton ATPase subunit G 1 chr9 GO:0016241 Not Cancer Driver No 9 0.0762711864406779 91 5 0.0423728813559322 0
ATP6V1G2-205 ATP6V1G2 O95670 V-type proton ATPase subunit G 2 chr6 GO:0016241 Not Cancer Driver No 10 0.0847457627118644 118 10 0.0847457627118644 0
ATP6V1H-202 ATP6V1H Q9UI12 V-type proton ATPase subunit H chr8 GO:0016241 Not Cancer Driver No 52 0.1076604554865424 35 2 0.0041407867494824 0
BECN1-213 BECN1 Q14457 Beclin-1 chr17 GO:0016241 Not Cancer Driver No 36 0.08 190 15 0.0333333333333333 0
CAPN1-201 CAPN1 P07384 Calpain-1 catalytic subunit chr11 GO:0016241 Not Cancer Driver No 51 0.0714285714285714 32 0 0.0 1
CAPNS1-201 CAPNS1 P04632 Calpain small subunit 1 chr19 GO:0016241 Not Cancer Driver No 21 0.0783582089552238 59 5 0.0186567164179104 0
CASP3-201 CASP3 P42574 Caspase-3 chr4 GO:0016241 Census Yes 19 0.0685920577617328 64 1 0.003610108303249 0
CDK5-204 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0016241 Not Cancer Driver No 38 0.1301369863013698 5 0 0.0 0
CDK5R1-201 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0016241 Not Cancer Driver No 29 0.0944625407166123 103 10 0.0325732899022801 0
ERN1-201 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0016241 Not Cancer Driver No 91 0.0931422722620266 251 17 0.0174002047082906 0
EXOC1-203 EXOC1 Q9NV70 Exocyst complex component 1 chr4 GO:0016241 Not Cancer Driver No 83 0.0928411633109619 154 14 0.0156599552572706 0
EXOC4-201 EXOC4 Q96A65 Exocyst complex component 4 chr7 GO:0016241 Not Cancer Driver No 128 0.1314168377823408 133 24 0.0246406570841889 0
EXOC7-202 EXOC7 Q9UPT5 Exocyst complex component 7 chr17 GO:0016241 Not Cancer Driver No 79 0.1074829931972789 209 22 0.0299319727891156 0
EXOC8-201 EXOC8 Q8IYI6 Exocyst complex component 8 chr1 GO:0016241 Not Cancer Driver No 60 0.0827586206896551 197 18 0.0248275862068965 0
GAPDH-201 GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 GO:0016241 Not Cancer Driver No 36 0.1074626865671641 24 3 0.008955223880597 0
GBA1-202 GBA1 P04062 Lysosomal acid glucosylceramidase chr1 GO:0016241 Not Cancer Driver No 60 0.1119402985074626 38 6 0.0111940298507462 157
HDAC6-201 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0016241 Not Cancer Driver No 122 0.1004115226337448 409 35 0.0288065843621399 0
MAPK8-206 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0016241 Not Cancer Driver No 52 0.1217798594847775 94 9 0.0210772833723653 0
MTMR8-201 MTMR8 Q96EF0 Myotubularin-related protein 8 chrX GO:0016241 Not Cancer Driver No 101 0.1434659090909091 55 4 0.0056818181818181 0
MTOR-201 MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0016241 Census, Compendium Yes 298 0.1169085916045508 298 28 0.0109846998823067 15
NEDD4-208 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 GO:0016241 Not Cancer Driver No 99 0.0750568612585291 717 55 0.0416982562547384 0
PIK3C3-201 PIK3C3 Q8NEB9 Phosphatidylinositol 3-kinase catalytic subunit type 3 chr18 GO:0016241 Not Cancer Driver No 101 0.1138669673055242 192 28 0.0315670800450958 0
PIK3R4-201 PIK3R4 Q99570 Phosphoinositide 3-kinase regulatory subunit 4 chr3 GO:0016241 Not Cancer Driver No 133 0.0979381443298969 315 32 0.0235640648011782 0
PRKAA2-201 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 GO:0016241 Not Cancer Driver No 90 0.1630434782608695 98 18 0.0326086956521739 0
PRKACA-201 PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 GO:0016241 Census Yes 49 0.1396011396011396 24 0 0.0 2
RHEB-201 RHEB Q15382 GTP-binding protein Rheb chr7 GO:0016241 Not Cancer Driver No 25 0.1358695652173913 0 0 0.0 0
SH3GLB1-201 SH3GLB1 Q9Y371 Endophilin-B1 chr1 GO:0016241 Not Cancer Driver No 30 0.0821917808219178 82 6 0.0164383561643835 0
SNX32-201 SNX32 Q86XE0 Sorting nexin-32 chr11 GO:0016241 Not Cancer Driver No 41 0.1017369727047146 86 10 0.0248138957816377 0
SNX5-201 SNX5 Q9Y5X3 Sorting nexin-5 chr20 GO:0016241 Not Cancer Driver No 22 0.0544554455445544 93 8 0.0198019801980198 0
SNX6-201 SNX6 Q9UNH7 Sorting nexin-6 chr14 GO:0016241 Not Cancer Driver No 22 0.0541871921182266 86 4 0.0098522167487684 0
UBQLN1-202 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 GO:0016241 Not Cancer Driver No 40 0.0679117147707979 545 38 0.064516129032258 0
UBQLN2-201 UBQLN2 Q9UHD9 Ubiquilin-2 chrX GO:0016241 Not Cancer Driver No 64 0.1025641025641025 581 61 0.0977564102564102 8
UCHL1-201 UCHL1 P09936 Ubiquitin carboxyl-terminal hydrolase isozyme L1 chr4 GO:0016241 Not Cancer Driver No 23 0.1031390134529148 34 5 0.0224215246636771 4
ULK1-201 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 GO:0016241 Not Cancer Driver No 125 0.119047619047619 591 66 0.0628571428571428 0
VPS26A-201 VPS26A O75436 Vacuolar protein sorting-associated protein 26A chr10 GO:0016241 Not Cancer Driver No 21 0.0642201834862385 45 3 0.0091743119266055 0
VPS26B-201 VPS26B Q4G0F5 Vacuolar protein sorting-associated protein 26B chr11 GO:0016241 Not Cancer Driver No 31 0.0922619047619047 52 2 0.0059523809523809 0
VPS35-201 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 GO:0016241 Not Cancer Driver No 55 0.0690954773869346 99 7 0.0087939698492462 1