Total number of protein in "GO:0016301" GO term: 59
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ABL1-201 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0016301 | Census, Compendium | Yes | 106 | 0.0938053097345132 | 609 | 53 | 0.0469026548672566 | 2 |
AKT1-218 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0016301 | Census, Compendium | Yes | 99 | 0.20625 | 158 | 19 | 0.0395833333333333 | 4 |
BCKDK-201 | BCKDK | O14874 | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | chr16 | GO:0016301 | Not Cancer Driver | No | 44 | 0.1067961165048543 | 39 | 2 | 0.0048543689320388 | 3 |
CAMK2A-201 | CAMK2A | Q9UQM7 | Calcium/calmodulin-dependent protein kinase type II subunit alpha | chr5 | GO:0016301 | Not Cancer Driver | No | 62 | 0.1297071129707113 | 62 | 10 | 0.0209205020920502 | 7 |
CCL3-204 | CCL3 | P10147 | C-C motif chemokine 3 | chr17 | GO:0016301 | Not Cancer Driver | No | 13 | 0.1413043478260869 | 0 | 0 | 0.0 | 0 |
CCNE1-201 | CCNE1 | P24864 | G1/S-specific cyclin-E1 | chr19 | GO:0016301 | Census | Yes | 44 | 0.1073170731707317 | 142 | 15 | 0.0365853658536585 | 0 |
CDC7-201 | CDC7 | O00311 | Cell division cycle 7-related protein kinase | chr1 | GO:0016301 | Not Cancer Driver | No | 49 | 0.0853658536585365 | 187 | 17 | 0.0296167247386759 | 0 |
CDK1-203 | CDK1 | P06493 | Cyclin-dependent kinase 1 | chr10 | GO:0016301 | Not Cancer Driver | No | 26 | 0.0875420875420875 | 1 | 0 | 0.0 | 0 |
CDK5-204 | CDK5 | Q00535 | Cyclin-dependent kinase 5 | chr7 | GO:0016301 | Not Cancer Driver | No | 38 | 0.1301369863013698 | 5 | 0 | 0.0 | 0 |
CDK5R1-201 | CDK5R1 | Q15078 | Cyclin-dependent kinase 5 activator 1 | chr17 | GO:0016301 | Not Cancer Driver | No | 29 | 0.0944625407166123 | 103 | 10 | 0.0325732899022801 | 0 |
CDK9-201 | CDK9 | P50750 | Cyclin-dependent kinase 9 | chr9 | GO:0016301 | Not Cancer Driver | No | 40 | 0.1075268817204301 | 34 | 2 | 0.0053763440860215 | 0 |
CDKL5-205 | CDKL5 | O76039 | Cyclin-dependent kinase-like 5 | chrX | GO:0016301 | Not Cancer Driver | No | 111 | 0.115625 | 685 | 79 | 0.0822916666666666 | 16 |
CERT1-215 | CERT1 | Q9Y5P4 | Ceramide transfer protein | chr5 | GO:0016301 | Not Cancer Driver | No | 51 | 0.0817307692307692 | 215 | 17 | 0.0272435897435897 | 2 |
COQ8A-201 | COQ8A | Q8NI60 | Atypical kinase COQ8A, mitochondrial | chr1 | GO:0016301 | Not Cancer Driver | No | 69 | 0.106646058732612 | 169 | 21 | 0.0324574961360123 | 10 |
CSNK2A1-201 | CSNK2A1 | P68400 | Casein kinase II subunit alpha | chr20 | GO:0016301 | Not Cancer Driver | No | 47 | 0.1202046035805626 | 75 | 6 | 0.0153452685421994 | 4 |
DGKA-201 | DGKA | P23743 | Diacylglycerol kinase alpha | chr12 | GO:0016301 | Not Cancer Driver | No | 64 | 0.0870748299319727 | 76 | 13 | 0.0176870748299319 | 0 |
DGKE-201 | DGKE | P52429 | Diacylglycerol kinase epsilon | chr17 | GO:0016301 | Not Cancer Driver | No | 61 | 0.1075837742504409 | 34 | 3 | 0.0052910052910052 | 3 |
DGKZ-205 | DGKZ | Q13574 | Diacylglycerol kinase zeta | chr11 | GO:0016301 | Not Cancer Driver | No | 65 | 0.0700431034482758 | 411 | 30 | 0.0323275862068965 | 0 |
EIF2AK2-201 | EIF2AK2 | P19525 | Interferon-induced, double-stranded RNA-activated protein kinase | chr2 | GO:0016301 | Not Cancer Driver | No | 36 | 0.0653357531760435 | 188 | 15 | 0.0272232304900181 | 1 |
EPHA4-201 | EPHA4 | P54764 | Ephrin type-A receptor 4 | chr2 | GO:0016301 | Not Cancer Driver | No | 132 | 0.1338742393509127 | 141 | 16 | 0.0162271805273833 | 0 |
FAM20B-201 | FAM20B | O75063 | Glycosaminoglycan xylosylkinase | chr1 | GO:0016301 | Not Cancer Driver | No | 34 | 0.0831295843520782 | 3 | 1 | 0.0024449877750611 | 0 |
FN3K-201 | FN3K | Q9H479 | Fructosamine-3-kinase | chr17 | GO:0016301 | Not Cancer Driver | No | 24 | 0.0776699029126213 | 40 | 1 | 0.0032362459546925 | 0 |
FN3KRP-201 | FN3KRP | Q9HA64 | Ketosamine-3-kinase | chr17 | GO:0016301 | Not Cancer Driver | No | 25 | 0.0809061488673139 | 75 | 4 | 0.0129449838187702 | 0 |
GSK3B-201 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | GO:0016301 | Not Cancer Driver | No | 34 | 0.0809523809523809 | 148 | 6 | 0.0142857142857142 | 0 |
IRAK1-203 | IRAK1 | P51617 | Interleukin-1 receptor-associated kinase 1 | chrX | GO:0016301 | Compendium | Yes | 60 | 0.0842696629213483 | 338 | 35 | 0.0491573033707865 | 0 |
IRAK4-212 | IRAK4 | Q9NWZ3 | Interleukin-1 receptor-associated kinase 4 | chr12 | GO:0016301 | Not Cancer Driver | No | 50 | 0.108695652173913 | 116 | 17 | 0.0369565217391304 | 2 |
LRRK2-201 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | GO:0016301 | Not Cancer Driver | No | 402 | 0.1590819153146023 | 91 | 13 | 0.0051444400474871 | 20 |
LYN-202 | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | GO:0016301 | Census | Yes | 78 | 0.15234375 | 85 | 10 | 0.01953125 | 0 |
MAPK15-201 | MAPK15 | Q8TD08 | Mitogen-activated protein kinase 15 | chr8 | GO:0016301 | Not Cancer Driver | No | 66 | 0.1213235294117647 | 236 | 32 | 0.0588235294117647 | 0 |
MASTL-202 | MASTL | Q96GX5 | Serine/threonine-protein kinase greatwall | chr10 | GO:0016301 | Not Cancer Driver | No | 68 | 0.0773606370875995 | 393 | 35 | 0.0398179749715585 | 0 |
MTOR-201 | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | GO:0016301 | Census, Compendium | Yes | 298 | 0.1169085916045508 | 298 | 28 | 0.0109846998823067 | 15 |
NEK1-201 | NEK1 | Q96PY6 | Serine/threonine-protein kinase Nek1 | chr4 | GO:0016301 | Not Cancer Driver | No | 78 | 0.0620031796502384 | 882 | 60 | 0.0476947535771065 | 3 |
PI4KA-201 | PI4KA | P42356 | Phosphatidylinositol 4-kinase alpha | chr22 | GO:0016301 | Not Cancer Driver | No | 198 | 0.0941960038058991 | 142 | 10 | 0.0047573739295908 | 7 |
PIK3C3-201 | PIK3C3 | Q8NEB9 | Phosphatidylinositol 3-kinase catalytic subunit type 3 | chr18 | GO:0016301 | Not Cancer Driver | No | 101 | 0.1138669673055242 | 192 | 28 | 0.0315670800450958 | 0 |
PIK3CA-201 | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0016301 | Census, Compendium | Yes | 1425 | 1.3342696629213484 | 38 | 9 | 0.0084269662921348 | 44 |
PIK3CB-214 | PIK3CB | P42338 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | chr3 | GO:0016301 | Census, Compendium | Yes | 112 | 0.1046728971962616 | 42 | 3 | 0.002803738317757 | 0 |
PIK3CD-202 | PIK3CD | O00329 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | chr1 | GO:0016301 | Not Cancer Driver | No | 116 | 0.1111111111111111 | 61 | 8 | 0.0076628352490421 | 1 |
PIK3CG-205 | PIK3CG | P48736 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | chr7 | GO:0016301 | Not Cancer Driver | No | 230 | 0.2087114337568058 | 122 | 28 | 0.0254083484573502 | 3 |
PINK1-201 | PINK1 | Q9BXM7 | Serine/threonine-protein kinase PINK1, mitochondrial | chr1 | GO:0016301 | Not Cancer Driver | No | 46 | 0.0791738382099827 | 99 | 8 | 0.0137693631669535 | 24 |
PKLR-201 | PKLR | P30613 | Pyruvate kinase PKLR | chr1 | GO:0016301 | Not Cancer Driver | No | 93 | 0.1620209059233449 | 26 | 5 | 0.0087108013937282 | 86 |
PKMYT1-201 | PKMYT1 | Q99640 | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | chr16 | GO:0016301 | Not Cancer Driver | No | 28 | 0.0561122244488977 | 228 | 14 | 0.0280561122244488 | 0 |
PKN2-203 | PKN2 | Q16513 | Serine/threonine-protein kinase N2 | chr1 | GO:0016301 | Not Cancer Driver | No | 76 | 0.0772357723577235 | 415 | 29 | 0.0294715447154471 | 0 |
PRKD1-201 | PRKD1 | Q15139 | Serine/threonine-protein kinase D1 | chr14 | GO:0016301 | Census | Yes | 164 | 0.1798245614035087 | 190 | 31 | 0.0339912280701754 | 2 |
PRKD3-201 | PRKD3 | O94806 | Serine/threonine-protein kinase D3 | chr2 | GO:0016301 | Not Cancer Driver | No | 90 | 0.1011235955056179 | 183 | 12 | 0.0134831460674157 | 0 |
PRPS1-204 | PRPS1 | P60891 | Ribose-phosphate pyrophosphokinase 1 | chrX | GO:0016301 | Not Cancer Driver | No | 28 | 0.0880503144654088 | 0 | 0 | 0.0 | 16 |
PRPS1L1-201 | PRPS1L1 | P21108 | Ribose-phosphate pyrophosphokinase 3 | chr7 | GO:0016301 | Not Cancer Driver | No | 62 | 0.1949685534591195 | 0 | 0 | 0.0 | 0 |
PRPS2-202 | PRPS2 | P11908 | Ribose-phosphate pyrophosphokinase 2 | chrX | GO:0016301 | Not Cancer Driver | No | 42 | 0.1320754716981132 | 4 | 1 | 0.0031446540880503 | 0 |
PSTK-202 | PSTK | Q8IV42 | L-seryl-tRNA(Sec) kinase | chr10 | GO:0016301 | Not Cancer Driver | No | 29 | 0.0833333333333333 | 80 | 10 | 0.028735632183908 | 0 |
SCYL3-203 | SCYL3 | Q8IZE3 | Protein-associating with the carboxyl-terminal domain of ezrin | chr1 | GO:0016301 | Not Cancer Driver | No | 56 | 0.0754716981132075 | 250 | 18 | 0.0242587601078167 | 0 |
SGMS1-202 | SGMS1 | Q86VZ5 | Phosphatidylcholine:ceramide cholinephosphotransferase 1 | chr10 | GO:0016301 | Not Cancer Driver | No | 65 | 0.1573849878934624 | 37 | 7 | 0.0169491525423728 | 0 |
SGMS2-210 | SGMS2 | Q8NHU3 | Phosphatidylcholine:ceramide cholinephosphotransferase 2 | chr4 | GO:0016301 | Not Cancer Driver | No | 20 | 0.0547945205479452 | 49 | 4 | 0.010958904109589 | 0 |
STK39-201 | STK39 | Q9UEW8 | STE20/SPS1-related proline-alanine-rich protein kinase | chr2 | GO:0016301 | Not Cancer Driver | No | 42 | 0.0770642201834862 | 183 | 13 | 0.0238532110091743 | 0 |
SYK-204 | SYK | P43405 | Tyrosine-protein kinase SYK | chr9 | GO:0016301 | Census | Yes | 75 | 0.1181102362204724 | 131 | 20 | 0.0314960629921259 | 4 |
TAF1-204 | TAF1 | P21675 | Transcription initiation factor TFIID subunit 1 | chrX | GO:0016301 | Not Cancer Driver | No | 278 | 0.1484249866524292 | 1174 | 156 | 0.0832888414308595 | 5 |
TAOK1-201 | TAOK1 | Q7L7X3 | Serine/threonine-protein kinase TAO1 | chr17 | GO:0016301 | Not Cancer Driver | No | 94 | 0.0939060939060939 | 602 | 48 | 0.0479520479520479 | 7 |
TPK1-201 | TPK1 | Q9H3S4 | Thiamin pyrophosphokinase 1 | chr7 | GO:0016301 | Not Cancer Driver | No | 39 | 0.1604938271604938 | 0 | 0 | 0.0 | 3 |
TRIB3-201 | TRIB3 | Q96RU7 | Tribbles homolog 3 | chr20 | GO:0016301 | Not Cancer Driver | No | 45 | 0.1256983240223463 | 113 | 17 | 0.047486033519553 | 0 |
TRRAP-202 | TRRAP | Q9Y4A5 | Transformation/transcription domain-associated protein | chr7 | GO:0016301 | Census, Compendium | Yes | 431 | 0.1116869655351127 | 402 | 47 | 0.0121793210676341 | 8 |
VRK1-201 | VRK1 | Q99986 | Serine/threonine-protein kinase VRK1 | chr14 | GO:0016301 | Not Cancer Driver | No | 34 | 0.0858585858585858 | 80 | 4 | 0.0101010101010101 | 0 |