Total number of protein in "GO:0016485" GO term: 84
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACTMAP-201 | ACTMAP | Q5BKX5 | Actin maturation protease | chr19 | GO:0016485 | Not Cancer Driver | No | 20 | 0.0569800569800569 | 143 | 3 | 0.0085470085470085 | 0 |
| ADAM10-201 | ADAM10 | O14672 | Disintegrin and metalloproteinase domain-containing protein 10 | chr15 | GO:0016485 | Not Cancer Driver | No | 73 | 0.0975935828877005 | 156 | 18 | 0.0240641711229946 | 4 |
| ADAM17-201 | ADAM17 | P78536 | Disintegrin and metalloproteinase domain-containing protein 17 | chr2 | GO:0016485 | Not Cancer Driver | No | 63 | 0.0764563106796116 | 182 | 17 | 0.020631067961165 | 0 |
| ADAM19-203 | ADAM19 | Q9H013 | Disintegrin and metalloproteinase domain-containing protein 19 | chr5 | GO:0016485 | Not Cancer Driver | No | 144 | 0.1507853403141361 | 372 | 61 | 0.0638743455497382 | 0 |
| ADAMTS13-206 | ADAMTS13 | Q76LX8 | A disintegrin and metalloproteinase with thrombospondin motifs 13 | chr9 | GO:0016485 | Not Cancer Driver | No | 138 | 0.0967063770147161 | 286 | 26 | 0.0182200420462508 | 42 |
| ADAMTS2-201 | ADAMTS2 | O95450 | A disintegrin and metalloproteinase with thrombospondin motifs 2 | chr5 | GO:0016485 | Not Cancer Driver | No | 237 | 0.1957060280759702 | 306 | 67 | 0.0553261767134599 | 0 |
| ADAMTS3-201 | ADAMTS3 | O15072 | A disintegrin and metalloproteinase with thrombospondin motifs 3 | chr4 | GO:0016485 | Not Cancer Driver | No | 184 | 0.1526970954356846 | 295 | 53 | 0.0439834024896265 | 3 |
| AEBP1-201 | AEBP1 | Q8IUX7 | Adipocyte enhancer-binding protein 1 | chr7 | GO:0016485 | Not Cancer Driver | No | 121 | 0.1044905008635578 | 691 | 71 | 0.0613126079447323 | 0 |
| AFG3L2-201 | AFG3L2 | Q9Y4W6 | AFG3-like protein 2 | chr18 | GO:0016485 | Not Cancer Driver | No | 38 | 0.0476787954830614 | 162 | 5 | 0.0062735257214554 | 17 |
| APH1A-203 | APH1A | Q96BI3 | Gamma-secretase subunit APH-1A | chr1 | GO:0016485 | Not Cancer Driver | No | 29 | 0.1094339622641509 | 0 | 0 | 0.0 | 0 |
| APH1B-201 | APH1B | Q8WW43 | Gamma-secretase subunit APH-1B | chr15 | GO:0016485 | Not Cancer Driver | No | 15 | 0.0583657587548638 | 0 | 0 | 0.0 | 0 |
| ATG4A-203 | ATG4A | Q8WYN0 | Cysteine protease ATG4A | chrX | GO:0016485 | Not Cancer Driver | No | 37 | 0.092964824120603 | 54 | 0 | 0.0 | 0 |
| ATG4B-205 | ATG4B | Q9Y4P1 | Cysteine protease ATG4B | chr2 | GO:0016485 | Not Cancer Driver | No | 24 | 0.0610687022900763 | 13 | 2 | 0.005089058524173 | 0 |
| ATG4C-201 | ATG4C | Q96DT6 | Cysteine protease ATG4C | chr1 | GO:0016485 | Not Cancer Driver | No | 45 | 0.0982532751091703 | 17 | 3 | 0.0065502183406113 | 0 |
| ATG4D-201 | ATG4D | Q86TL0 | Cysteine protease ATG4D | chr19 | GO:0016485 | Not Cancer Driver | No | 57 | 0.120253164556962 | 107 | 12 | 0.0253164556962025 | 0 |
| BACE1-201 | BACE1 | P56817 | Beta-secretase 1 | chr11 | GO:0016485 | Not Cancer Driver | No | 34 | 0.0678642714570858 | 53 | 2 | 0.0039920159680638 | 0 |
| BACE2-202 | BACE2 | Q9Y5Z0 | Beta-secretase 2 | chr21 | GO:0016485 | Not Cancer Driver | No | 47 | 0.0907335907335907 | 23 | 1 | 0.0019305019305019 | 0 |
| BMP1-202 | BMP1 | P13497 | Bone morphogenetic protein 1 | chr8 | GO:0016485 | Not Cancer Driver | No | 93 | 0.0943204868154158 | 154 | 23 | 0.0233265720081135 | 3 |
| C2CD3-202 | C2CD3 | Q4AC94 | C2 domain-containing protein 3 | chr11 | GO:0016485 | Not Cancer Driver | No | 183 | 0.0777730556736081 | 1105 | 74 | 0.0314492137696557 | 1 |
| CASP2-201 | CASP2 | P42575 | Caspase-2 | chr7 | GO:0016485 | Not Cancer Driver | No | 49 | 0.1084070796460177 | 42 | 11 | 0.0243362831858407 | 0 |
| CASP3-201 | CASP3 | P42574 | Caspase-3 | chr4 | GO:0016485 | Census | Yes | 19 | 0.0685920577617328 | 64 | 1 | 0.003610108303249 | 0 |
| CASP7-203 | CASP7 | P55210 | Caspase-7 | chr10 | GO:0016485 | Not Cancer Driver | No | 28 | 0.0924092409240924 | 75 | 7 | 0.0231023102310231 | 0 |
| CASP9-201 | CASP9 | P55211 | Caspase-9 | chr1 | GO:0016485 | Census | Yes | 26 | 0.0625 | 71 | 7 | 0.016826923076923 | 0 |
| CLN3-243 | CLN3 | Q13286 | Battenin | chr16 | GO:0016485 | Not Cancer Driver | No | 42 | 0.0958904109589041 | 69 | 5 | 0.0114155251141552 | 8 |
| COMP-201 | COMP | P49747 | Cartilage oligomeric matrix protein | chr19 | GO:0016485 | Not Cancer Driver | No | 75 | 0.0990752972258916 | 307 | 39 | 0.0515191545574636 | 51 |
| CPD-201 | CPD | O75976 | Carboxypeptidase D | chr17 | GO:0016485 | Not Cancer Driver | No | 90 | 0.0652173913043478 | 476 | 33 | 0.0239130434782608 | 0 |
| CPE-201 | CPE | P16870 | Carboxypeptidase E | chr4 | GO:0016485 | Not Cancer Driver | No | 67 | 0.1407563025210084 | 127 | 17 | 0.0357142857142857 | 0 |
| CPLANE2-201 | CPLANE2 | Q9BU20 | Ciliogenesis and planar polarity effector 2 | chr1 | GO:0016485 | Not Cancer Driver | No | 28 | 0.1085271317829457 | 21 | 3 | 0.0116279069767441 | 0 |
| CPM-211 | CPM | P14384 | Carboxypeptidase M | chr12 | GO:0016485 | Not Cancer Driver | No | 48 | 0.1083521444695259 | 16 | 1 | 0.0022573363431151 | 0 |
| CPN1-201 | CPN1 | P15169 | Carboxypeptidase N catalytic chain | chr10 | GO:0016485 | Not Cancer Driver | No | 80 | 0.1746724890829694 | 125 | 23 | 0.0502183406113537 | 1 |
| CPZ-202 | CPZ | Q66K79 | Carboxypeptidase Z | chr4 | GO:0016485 | Not Cancer Driver | No | 137 | 0.210122699386503 | 73 | 30 | 0.0460122699386503 | 0 |
| CTSG-201 | CTSG | P08311 | Cathepsin G | chr14 | GO:0016485 | Not Cancer Driver | No | 56 | 0.2196078431372549 | 81 | 25 | 0.0980392156862745 | 0 |
| CTSS-201 | CTSS | P25774 | Cathepsin S | chr1 | GO:0016485 | Not Cancer Driver | No | 40 | 0.120845921450151 | 0 | 0 | 0.0 | 0 |
| DDI2-202 | DDI2 | Q5TDH0 | Protein DDI1 homolog 2 | chr1 | GO:0016485 | Not Cancer Driver | No | 38 | 0.0952380952380952 | 187 | 24 | 0.0601503759398496 | 0 |
| DYNC2H1-202 | DYNC2H1 | Q8NCM8 | Cytoplasmic dynein 2 heavy chain 1 | chr11 | GO:0016485 | Not Cancer Driver | No | 378 | 0.0877641049454376 | 285 | 9 | 0.0020896215463199 | 34 |
| ECE1-203 | ECE1 | P42892 | Endothelin-converting enzyme 1 | chr1 | GO:0016485 | Not Cancer Driver | No | 95 | 0.1233766233766233 | 99 | 21 | 0.0272727272727272 | 1 |
| ECE2-201 | ECE2 | P0DPD6 | Endothelin-converting enzyme 2 | chr3 | GO:0016485 | Not Cancer Driver | No | 120 | 0.1479654747225647 | 150 | 22 | 0.0271270036991368 | 0 |
| ECEL1-201 | ECEL1 | O95672 | Endothelin-converting enzyme-like 1 | chr2 | GO:0016485 | Not Cancer Driver | No | 95 | 0.1225806451612903 | 22 | 2 | 0.0025806451612903 | 4 |
| EEF1AKMT4-ECE2-201 | EEF1AKMT4-ECE2 | P0DPD8 | EEF1AKMT4-ECE2 readthrough transcript protein | chr3 | GO:0016485 | Not Cancer Driver | No | 137 | 0.1551528878822197 | 100 | 25 | 0.0283125707814269 | 0 |
| ENST00000636766 | CLN3 | Q13286 | Battenin | chr16 | GO:0016485 | Not Cancer Driver | No | 0 | 0.0 | 0 | 0 | 0.0 | 0 |
| ENST00000676884 | PSEN2 | P49810 | Presenilin-2 | chr1 | GO:0016485 | Not Cancer Driver | No | 0 | 0.0 | 0 | 0 | 0.0 | 0 |
| F12-201 | F12 | P00748 | Coagulation factor XII | chr5 | GO:0016485 | Not Cancer Driver | No | 51 | 0.0829268292682926 | 104 | 9 | 0.0146341463414634 | 12 |
| F3-201 | F3 | P13726 | Tissue factor | chr1 | GO:0016485 | Not Cancer Driver | No | 18 | 0.0610169491525423 | 61 | 4 | 0.0135593220338983 | 0 |
| F7-202 | F7 | P08709 | Coagulation factor VII | chr13 | GO:0016485 | Not Cancer Driver | No | 56 | 0.1201716738197424 | 51 | 7 | 0.0150214592274678 | 88 |
| FKRP-201 | FKRP | Q9H9S5 | Ribitol 5-phosphate transferase FKRP | chr19 | GO:0016485 | Not Cancer Driver | No | 30 | 0.0606060606060606 | 22 | 2 | 0.004040404040404 | 32 |
| FURIN-201 | FURIN | P09958 | Furin | chr15 | GO:0016485 | Not Cancer Driver | No | 72 | 0.0906801007556675 | 283 | 30 | 0.0377833753148614 | 0 |
| GLG1-202 | GLG1 | Q92896 | Golgi apparatus protein 1 | chr16 | GO:0016485 | Not Cancer Driver | No | 97 | 0.0822731128074639 | 103 | 4 | 0.003392705682782 | 0 |
| GLI3-201 | GLI3 | P10071 | Transcriptional activator GLI3 | chr7 | GO:0016485 | Not Cancer Driver | No | 308 | 0.1949367088607595 | 1362 | 270 | 0.170886075949367 | 7 |
| IFT172-201 | IFT172 | Q9UG01 | Intraflagellar transport protein 172 homolog | chr2 | GO:0016485 | Not Cancer Driver | No | 154 | 0.0880503144654088 | 96 | 4 | 0.0022870211549456 | 8 |
| IL1R2-201 | IL1R2 | P27930 | Interleukin-1 receptor type 2 | chr2 | GO:0016485 | Not Cancer Driver | No | 47 | 0.1180904522613065 | 32 | 5 | 0.0125628140703517 | 0 |
| KEL-201 | KEL | P23276 | Kell blood group glycoprotein | chr7 | GO:0016485 | Compendium | Yes | 189 | 0.2581967213114754 | 117 | 37 | 0.0505464480874316 | 0 |
| KLK13-206 | KLK13 | Q9UKR3 | Kallikrein-13 | chr19 | GO:0016485 | Not Cancer Driver | No | 50 | 0.1805054151624548 | 78 | 10 | 0.0361010830324909 | 0 |
| LONP2-201 | LONP2 | Q86WA8 | Lon protease homolog 2, peroxisomal | chr16 | GO:0016485 | Not Cancer Driver | No | 85 | 0.0997652582159624 | 163 | 21 | 0.0246478873239436 | 0 |
| MAFB-201 | MAFB | Q9Y5Q3 | Transcription factor MafB | chr20 | GO:0016485 | Census | Yes | 29 | 0.0897832817337461 | 301 | 28 | 0.0866873065015479 | 8 |
| MBTPS1-201 | MBTPS1 | Q14703 | Membrane-bound transcription factor site-1 protease | chr16 | GO:0016485 | Not Cancer Driver | No | 120 | 0.1140684410646387 | 209 | 31 | 0.029467680608365 | 1 |
| METAP2-202 | METAP2 | P50579 | Methionine aminopeptidase 2 | chr12 | GO:0016485 | Not Cancer Driver | No | 36 | 0.0753138075313807 | 177 | 14 | 0.0292887029288702 | 0 |
| MME-201 | MME | P08473 | Neprilysin | chr3 | GO:0016485 | Not Cancer Driver | No | 156 | 0.208 | 40 | 17 | 0.0226666666666666 | 4 |
| MMEL1-201 | MMEL1 | Q495T6 | Membrane metallo-endopeptidase-like 1 | chr1 | GO:0016485 | Not Cancer Driver | No | 102 | 0.1309370988446726 | 46 | 5 | 0.0064184852374839 | 0 |
| MMP14-201 | MMP14 | P50281 | Matrix metalloproteinase-14 | chr14 | GO:0016485 | Not Cancer Driver | No | 50 | 0.0859106529209622 | 120 | 6 | 0.0103092783505154 | 1 |
| MMP16-201 | MMP16 | P51512 | Matrix metalloproteinase-16 | chr8 | GO:0016485 | Not Cancer Driver | No | 196 | 0.3228995057660626 | 168 | 52 | 0.085667215815486 | 0 |
| NAGLU-201 | NAGLU | P54802 | Alpha-N-acetylglucosaminidase | chr17 | GO:0016485 | Not Cancer Driver | No | 57 | 0.0767160161507402 | 18 | 0 | 0.0 | 61 |
| NCSTN-201 | NCSTN | Q92542 | Nicastrin | chr1 | GO:0016485 | Not Cancer Driver | No | 69 | 0.0973201692524682 | 72 | 10 | 0.0141043723554301 | 1 |
| OGT-202 | OGT | O15294 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | chrX | GO:0016485 | Not Cancer Driver | No | 111 | 0.1061185468451242 | 90 | 9 | 0.008604206500956 | 2 |
| P2RX7-202 | P2RX7 | Q99572 | P2X purinoceptor 7 | chr12 | GO:0016485 | Not Cancer Driver | No | 37 | 0.0621848739495798 | 16 | 1 | 0.0016806722689075 | 0 |
| PARL-202 | PARL | Q9H300 | Presenilin-associated rhomboid-like protein, mitochondrial | chr3 | GO:0016485 | Not Cancer Driver | No | 38 | 0.100263852242744 | 28 | 5 | 0.0131926121372031 | 0 |
| PCSK4-201 | PCSK4 | Q6UW60 | Proprotein convertase subtilisin/kexin type 4 | chr19 | GO:0016485 | Not Cancer Driver | No | 73 | 0.0966887417218543 | 150 | 18 | 0.023841059602649 | 0 |
| PCSK5-205 | PCSK5 | Q92824 | Proprotein convertase subtilisin/kexin type 5 | chr9 | GO:0016485 | Not Cancer Driver | No | 259 | 0.139247311827957 | 170 | 20 | 0.010752688172043 | 0 |
| PCSK6-214 | PCSK6 | P29122 | Proprotein convertase subtilisin/kexin type 6 | chr15 | GO:0016485 | Not Cancer Driver | No | 113 | 0.1166150670794633 | 207 | 41 | 0.0423116615067079 | 0 |
| PCSK7-201 | PCSK7 | Q16549 | Proprotein convertase subtilisin/kexin type 7 | chr11 | GO:0016485 | Not Cancer Driver | No | 80 | 0.1019108280254777 | 267 | 24 | 0.0305732484076433 | 0 |
| PHEX-201 | PHEX | P78562 | Phosphate-regulating neutral endopeptidase PHEX | chrX | GO:0016485 | Not Cancer Driver | No | 100 | 0.1335113484646194 | 56 | 4 | 0.0053404539385847 | 27 |
| PITRM1-201 | PITRM1 | Q5JRX3 | Presequence protease, mitochondrial | chr10 | GO:0016485 | Not Cancer Driver | No | 70 | 0.0675024108003857 | 222 | 16 | 0.0154291224686595 | 2 |
| PSEN1-201 | PSEN1 | P49768 | Presenilin-1 | chr14 | GO:0016485 | Not Cancer Driver | No | 43 | 0.0920770877944325 | 134 | 18 | 0.038543897216274 | 69 |
| PSEN2-202 | PSEN2 | P49810 | Presenilin-2 | chr1 | GO:0016485 | Not Cancer Driver | No | 58 | 0.1294642857142857 | 91 | 13 | 0.0290178571428571 | 4 |
| PSENEN-202 | PSENEN | Q9NZ42 | Gamma-secretase subunit PEN-2 | chr19 | GO:0016485 | Not Cancer Driver | No | 14 | 0.1386138613861386 | 0 | 0 | 0.0 | 0 |
| PTCH1-201 | PTCH1 | Q13635 | Protein patched homolog 1 | chr9 | GO:0016485 | Census, Compendium | Yes | 156 | 0.1078092605390463 | 383 | 39 | 0.0269523151347615 | 17 |
| SDE2-201 | SDE2 | Q6IQ49 | Splicing regulator SDE2 | chr1 | GO:0016485 | Not Cancer Driver | No | 40 | 0.0886917960088691 | 290 | 23 | 0.0509977827050997 | 0 |
| SPON1-201 | SPON1 | Q9HCB6 | Spondin-1 | chr11 | GO:0016485 | Not Cancer Driver | No | 0 | 0.0 | 192 | 0 | 0.0 | 0 |
| SRGN-201 | SRGN | P10124 | Serglycin | chr10 | GO:0016485 | Not Cancer Driver | No | 20 | 0.1265822784810126 | 89 | 10 | 0.0632911392405063 | 0 |
| TLL1-201 | TLL1 | O43897 | Tolloid-like protein 1 | chr4 | GO:0016485 | Compendium | Yes | 268 | 0.2645607107601184 | 139 | 51 | 0.050345508390918 | 3 |
| TLL2-201 | TLL2 | Q9Y6L7 | Tolloid-like protein 2 | chr10 | GO:0016485 | Not Cancer Driver | No | 138 | 0.1359605911330049 | 176 | 26 | 0.025615763546798 | 0 |
| TMPRSS12-201 | TMPRSS12 | Q86WS5 | Transmembrane protease serine 12 | chr12 | GO:0016485 | Not Cancer Driver | No | 33 | 0.0948275862068965 | 45 | 7 | 0.0201149425287356 | 0 |
| TMPRSS4-201 | TMPRSS4 | Q9NRS4 | Transmembrane protease serine 4 | chr11 | GO:0016485 | Not Cancer Driver | No | 41 | 0.0938215102974828 | 34 | 1 | 0.0022883295194508 | 0 |
| TYSND1-201 | TYSND1 | Q2T9J0 | Peroxisomal leader peptide-processing protease | chr10 | GO:0016485 | Not Cancer Driver | No | 25 | 0.0441696113074204 | 136 | 10 | 0.0176678445229682 | 0 |
| XPNPEP3-201 | XPNPEP3 | Q9NQH7 | Xaa-Pro aminopeptidase 3 | chr22 | GO:0016485 | Not Cancer Driver | No | 43 | 0.0848126232741617 | 129 | 10 | 0.019723865877712 | 1 |