Total number of protein in "GO:0016525" GO term: 90
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCC8-202 | ABCC8 | Q09428 | ATP-binding cassette sub-family C member 8 | chr11 | GO:0016525 | Not Cancer Driver | No | 186 | 0.1176470588235294 | 136 | 18 | 0.0113851992409867 | 88 |
| ADAMTS1-201 | ADAMTS1 | Q9UHI8 | A disintegrin and metalloproteinase with thrombospondin motifs 1 | chr21 | GO:0016525 | Not Cancer Driver | No | 101 | 0.1044467425025853 | 275 | 26 | 0.0268872802481902 | 0 |
| ADGRB1-201 | ADGRB1 | O14514 | Adhesion G protein-coupled receptor B1 | chr8 | GO:0016525 | Compendium | Yes | 170 | 0.1073232323232323 | 487 | 39 | 0.0246212121212121 | 0 |
| ADGRB2-202 | ADGRB2 | O60241 | Adhesion G protein-coupled receptor B2 | chr1 | GO:0016525 | Not Cancer Driver | No | 163 | 0.1028391167192429 | 538 | 63 | 0.0397476340694006 | 1 |
| ADGRB3-202 | ADGRB3 | O60242 | Adhesion G protein-coupled receptor B3 | chr6 | GO:0016525 | Not Cancer Driver | No | 429 | 0.2818659658344284 | 336 | 120 | 0.0788436268068331 | 0 |
| AGO1-201 | AGO1 | Q9UL18 | Protein argonaute-1 | chr1 | GO:0016525 | Not Cancer Driver | No | 94 | 0.1096849474912485 | 87 | 10 | 0.0116686114352392 | 1 |
| ALOX5-201 | ALOX5 | P09917 | Polyunsaturated fatty acid 5-lipoxygenase | chr10 | GO:0016525 | Not Cancer Driver | No | 100 | 0.1483679525222551 | 16 | 1 | 0.0014836795252225 | 0 |
| AMOT-203 | AMOT | Q4VCS5 | Angiomotin | chrX | GO:0016525 | Not Cancer Driver | No | 103 | 0.0950184501845018 | 911 | 85 | 0.0784132841328413 | 0 |
| ANGPT2-201 | ANGPT2 | O15123 | Angiopoietin-2 | chr8 | GO:0016525 | Not Cancer Driver | No | 44 | 0.0887096774193548 | 96 | 7 | 0.0141129032258064 | 1 |
| ANGPT4-201 | ANGPT4 | Q9Y264 | Angiopoietin-4 | chr20 | GO:0016525 | Not Cancer Driver | No | 87 | 0.172962226640159 | 152 | 31 | 0.0616302186878727 | 0 |
| APOH-201 | APOH | P02749 | Beta-2-glycoprotein 1 | chr17 | GO:0016525 | Not Cancer Driver | No | 45 | 0.1304347826086956 | 0 | 0 | 0.0 | 0 |
| ATF2-201 | ATF2 | P15336 | Cyclic AMP-dependent transcription factor ATF-2 | chr2 | GO:0016525 | Not Cancer Driver | No | 42 | 0.0831683168316831 | 451 | 36 | 0.0712871287128712 | 0 |
| ATP2B4-203 | ATP2B4 | P23634 | Plasma membrane calcium-transporting ATPase 4 | chr1 | GO:0016525 | Not Cancer Driver | No | 113 | 0.0937759336099585 | 264 | 20 | 0.0165975103734439 | 0 |
| CCN6-203 | CCN6 | O95389 | Cellular communication network factor 6 | chr6 | GO:0016525 | Not Cancer Driver | No | 26 | 0.0734463276836158 | 11 | 0 | 0.0 | 6 |
| CCR2-201 | CCR2 | P41597 | C-C chemokine receptor type 2 | chr3 | GO:0016525 | Not Cancer Driver | No | 56 | 0.1497326203208556 | 23 | 2 | 0.0053475935828877 | 0 |
| CD160-202 | CD160 | O95971 | CD160 antigen | chr1 | GO:0016525 | Not Cancer Driver | No | 16 | 0.0883977900552486 | 2 | 0 | 0.0 | 0 |
| CLDN5-204 | CLDN5 | O00501 | Claudin-5 | chr22 | GO:0016525 | Not Cancer Driver | No | 17 | 0.0779816513761468 | 0 | 0 | 0.0 | 0 |
| CNMD-201 | CNMD | O75829 | Leukocyte cell-derived chemotaxin 1 | chr13 | GO:0016525 | Not Cancer Driver | No | 39 | 0.1167664670658682 | 64 | 9 | 0.0269461077844311 | 0 |
| COL4A2-201 | COL4A2 | P08572 | Collagen alpha-2(IV) chain | chr13 | GO:0016525 | Not Cancer Driver | No | 109 | 0.0636682242990654 | 1467 | 89 | 0.0519859813084112 | 3 |
| COL4A3-202 | COL4A3 | Q01955 | Collagen alpha-3(IV) chain | chr2 | GO:0016525 | Not Cancer Driver | No | 58 | 0.0347305389221556 | 1435 | 36 | 0.0215568862275449 | 13 |
| CTNNB1-201 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | GO:0016525 | Census, Compendium | Yes | 363 | 0.4647887323943662 | 288 | 291 | 0.3725992317541613 | 11 |
| CXCL10-201 | CXCL10 | P02778 | C-X-C motif chemokine 10 | chr4 | GO:0016525 | Not Cancer Driver | No | 11 | 0.1122448979591836 | 12 | 1 | 0.010204081632653 | 0 |
| DAB2IP-203 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:0016525 | Not Cancer Driver | No | 95 | 0.0798990748528175 | 682 | 49 | 0.04121110176619 | 0 |
| DCN-201 | DCN | P07585 | Decorin | chr12 | GO:0016525 | Not Cancer Driver | No | 74 | 0.2061281337047353 | 81 | 21 | 0.0584958217270195 | 0 |
| ECSCR-201 | ECSCR | Q19T08 | Endothelial cell-specific chemotaxis regulator | chr5 | GO:0016525 | Not Cancer Driver | No | 5 | 0.024390243902439 | 127 | 3 | 0.0146341463414634 | 0 |
| EFNA3-201 | EFNA3 | P52797 | Ephrin-A3 | chr1 | GO:0016525 | Not Cancer Driver | No | 18 | 0.0756302521008403 | 31 | 7 | 0.0294117647058823 | 0 |
| EMILIN1-201 | EMILIN1 | Q9Y6C2 | EMILIN-1 | chr2 | GO:0016525 | Not Cancer Driver | No | 89 | 0.0875984251968503 | 671 | 50 | 0.0492125984251968 | 1 |
| ENST00000515823 | ECSCR | Q19T08 | Endothelial cell-specific chemotaxis regulator | chr5 | GO:0016525 | Not Cancer Driver | No | 5 | 0.024390243902439 | 127 | 3 | 0.0146341463414634 | 0 |
| EPHA2-201 | EPHA2 | P29317 | Ephrin type-A receptor 2 | chr1 | GO:0016525 | Compendium | Yes | 147 | 0.1506147540983606 | 188 | 33 | 0.033811475409836 | 3 |
| FASLG-202 | FASLG | P48023 | Tumor necrosis factor ligand superfamily member 6 | chr1 | GO:0016525 | Not Cancer Driver | No | 51 | 0.1814946619217081 | 94 | 15 | 0.0533807829181494 | 1 |
| FOXC1-201 | FOXC1 | Q12948 | Forkhead box protein C1 | chr6 | GO:0016525 | Not Cancer Driver | No | 23 | 0.0415913200723327 | 409 | 14 | 0.0253164556962025 | 25 |
| FOXJ2-201 | FOXJ2 | Q9P0K8 | Forkhead box protein J2 | chr12 | GO:0016525 | Not Cancer Driver | No | 57 | 0.0993031358885017 | 486 | 47 | 0.0818815331010452 | 0 |
| FOXO4-202 | FOXO4 | P98177 | Forkhead box protein O4 | chrX | GO:0016525 | Census | Yes | 56 | 0.1108910891089108 | 441 | 45 | 0.0891089108910891 | 0 |
| GADD45A-202 | GADD45A | P24522 | Growth arrest and DNA damage-inducible protein GADD45 alpha | chr1 | GO:0016525 | Not Cancer Driver | No | 8 | 0.0484848484848484 | 40 | 4 | 0.0242424242424242 | 0 |
| GDF2-201 | GDF2 | Q9UK05 | Growth/differentiation factor 2 | chr10 | GO:0016525 | Not Cancer Driver | No | 106 | 0.247086247086247 | 130 | 40 | 0.0932400932400932 | 3 |
| GHRL-202 | GHRL | Q9UBU3 | Appetite-regulating hormone | chr3 | GO:0016525 | Not Cancer Driver | No | 13 | 0.1111111111111111 | 52 | 8 | 0.0683760683760683 | 0 |
| GPR4-201 | GPR4 | P46093 | G-protein coupled receptor 4 | chr19 | GO:0016525 | Not Cancer Driver | No | 45 | 0.1243093922651933 | 44 | 5 | 0.0138121546961325 | 0 |
| GTF2I-212 | GTF2I | P78347 | General transcription factor II-I | chr7 | GO:0016525 | Compendium | Yes | 122 | 0.1222444889779559 | 365 | 27 | 0.0270541082164328 | 0 |
| HGS-201 | HGS | O14964 | Hepatocyte growth factor-regulated tyrosine kinase substrate | chr17 | GO:0016525 | Not Cancer Driver | No | 83 | 0.1068211068211068 | 535 | 62 | 0.0797940797940797 | 0 |
| HHEX-201 | HHEX | Q03014 | Hematopoietically-expressed homeobox protein HHEX | chr10 | GO:0016525 | Not Cancer Driver | No | 13 | 0.0481481481481481 | 193 | 12 | 0.0444444444444444 | 0 |
| HLA-G-201 | HLA-G | P17693 | HLA class I histocompatibility antigen, alpha chain G | chr6 | GO:0016525 | Not Cancer Driver | No | 52 | 0.1538461538461538 | 85 | 20 | 0.059171597633136 | 0 |
| HOXA5-201 | HOXA5 | P20719 | Homeobox protein Hox-A5 | chr7 | GO:0016525 | Not Cancer Driver | No | 40 | 0.1481481481481481 | 209 | 33 | 0.1222222222222222 | 0 |
| HRG-201 | HRG | P04196 | Histidine-rich glycoprotein | chr3 | GO:0016525 | Not Cancer Driver | No | 83 | 0.1580952380952381 | 283 | 57 | 0.1085714285714285 | 2 |
| HSPG2-203 | HSPG2 | P98160 | Basement membrane-specific heparan sulfate proteoglycan core protein | chr1 | GO:0016525 | Compendium | Yes | 414 | 0.0942837622409474 | 1724 | 160 | 0.0364381689820086 | 1 |
| IL17F-201 | IL17F | Q96PD4 | Interleukin-17F | chr6 | GO:0016525 | Not Cancer Driver | No | 33 | 0.2024539877300613 | 34 | 8 | 0.0490797546012269 | 1 |
| ISM1-201 | ISM1 | B1AKI9 | Isthmin-1 | chr20 | GO:0016525 | Not Cancer Driver | No | 53 | 0.1142241379310344 | 217 | 29 | 0.0625 | 0 |
| KLF4-201 | KLF4 | O43474 | Krueppel-like factor 4 | chr9 | GO:0016525 | Census, Compendium | Yes | 41 | 0.0855949895615866 | 417 | 25 | 0.0521920668058455 | 0 |
| KLK3-201 | KLK3 | P07288 | Prostate-specific antigen | chr19 | GO:0016525 | Not Cancer Driver | No | 54 | 0.2068965517241379 | 6 | 0 | 0.0 | 0 |
| KRIT1-203 | KRIT1 | O00522 | Krev interaction trapped protein 1 | chr7 | GO:0016525 | Not Cancer Driver | No | 65 | 0.0883152173913043 | 113 | 16 | 0.0217391304347826 | 2 |
| MECP2-201 | MECP2 | P51608 | Methyl-CpG-binding protein 2 | chrX | GO:0016525 | Not Cancer Driver | No | 44 | 0.0905349794238683 | 482 | 43 | 0.088477366255144 | 32 |
| MINAR1-201 | MINAR1 | Q9UPX6 | Major intrinsically disordered Notch2-binding receptor 1 | chr15 | GO:0016525 | Not Cancer Driver | No | 119 | 0.1299126637554585 | 589 | 74 | 0.0807860262008733 | 0 |
| NAXE-203 | NAXE | Q8NCW5 | NAD(P)H-hydrate epimerase | chr1 | GO:0016525 | Not Cancer Driver | No | 14 | 0.0486111111111111 | 5 | 0 | 0.0 | 2 |
| NF1-202 | NF1 | P21359 | Neurofibromin | chr17 | GO:0016525 | Census, Compendium | Yes | 285 | 0.1003874603733709 | 406 | 36 | 0.0126805213103205 | 75 |
| NIBAN2-201 | NIBAN2 | Q96TA1 | Protein Niban 2 | chr9 | GO:0016525 | Not Cancer Driver | No | 82 | 0.1099195710455764 | 206 | 19 | 0.0254691689008042 | 0 |
| NPPB-201 | NPPB | P16860 | Natriuretic peptides B | chr1 | GO:0016525 | Not Cancer Driver | No | 25 | 0.1865671641791045 | 104 | 22 | 0.1641791044776119 | 0 |
| NPR1-202 | NPR1 | P16066 | Atrial natriuretic peptide receptor 1 | chr1 | GO:0016525 | Not Cancer Driver | No | 105 | 0.0989632422243166 | 78 | 16 | 0.0150801131008482 | 0 |
| PDE3B-201 | PDE3B | Q13370 | cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B | chr11 | GO:0016525 | Not Cancer Driver | No | 101 | 0.0908273381294964 | 394 | 24 | 0.0215827338129496 | 0 |
| PF4-201 | PF4 | P02776 | Platelet factor 4 | chr4 | GO:0016525 | Not Cancer Driver | No | 11 | 0.1089108910891089 | 0 | 0 | 0.0 | 0 |
| PGK1-201 | PGK1 | P00558 | Phosphoglycerate kinase 1 | chrX | GO:0016525 | Not Cancer Driver | No | 44 | 0.105515587529976 | 40 | 3 | 0.0071942446043165 | 9 |
| PLK2-201 | PLK2 | Q9NYY3 | Serine/threonine-protein kinase PLK2 | chr5 | GO:0016525 | Not Cancer Driver | No | 55 | 0.0802919708029197 | 180 | 18 | 0.0262773722627737 | 0 |
| PML-201 | PML | P29590 | Protein PML | chr15 | GO:0016525 | Census, Compendium | Yes | 87 | 0.0986394557823129 | 312 | 28 | 0.0317460317460317 | 0 |
| PPARG-201 | PPARG | P37231 | Peroxisome proliferator-activated receptor gamma | chr3 | GO:0016525 | Census | Yes | 60 | 0.1188118811881188 | 44 | 3 | 0.0059405940594059 | 3 |
| PRL-201 | PRL | P01236 | Prolactin | chr6 | GO:0016525 | Not Cancer Driver | No | 37 | 0.1629955947136563 | 22 | 1 | 0.0044052863436123 | 0 |
| PTPRM-201 | PTPRM | P28827 | Receptor-type tyrosine-protein phosphatase mu | chr18 | GO:0016525 | Not Cancer Driver | No | 199 | 0.1370523415977961 | 368 | 45 | 0.03099173553719 | 0 |
| RELA-202 | RELA | Q04206 | Transcription factor p65 | chr11 | GO:0016525 | Compendium | Yes | 53 | 0.0961887477313974 | 401 | 32 | 0.058076225045372 | 0 |
| RGCC-201 | RGCC | Q9H4X1 | Regulator of cell cycle RGCC | chr13 | GO:0016525 | Not Cancer Driver | No | 4 | 0.0291970802919708 | 81 | 2 | 0.0145985401459854 | 0 |
| ROCK1-201 | ROCK1 | Q13464 | Rho-associated protein kinase 1 | chr18 | GO:0016525 | Not Cancer Driver | No | 116 | 0.0856720827178729 | 780 | 61 | 0.0450516986706056 | 0 |
| ROCK2-202 | ROCK2 | O75116 | Rho-associated protein kinase 2 | chr2 | GO:0016525 | Not Cancer Driver | No | 110 | 0.0792507204610951 | 734 | 61 | 0.0439481268011527 | 0 |
| SARS1-201 | SARS1 | P49591 | Serine--tRNA ligase, cytoplasmic | chr1 | GO:0016525 | Not Cancer Driver | No | 42 | 0.0817120622568093 | 83 | 4 | 0.0077821011673151 | 2 |
| SEMA3E-204 | SEMA3E | O15041 | Semaphorin-3E | chr7 | GO:0016525 | Not Cancer Driver | No | 162 | 0.2090322580645161 | 87 | 24 | 0.0309677419354838 | 0 |
| SEMA4A-204 | SEMA4A | Q9H3S1 | Semaphorin-4A | chr1 | GO:0016525 | Not Cancer Driver | No | 101 | 0.1327201051248357 | 122 | 17 | 0.0223390275952693 | 4 |
| SEMA6A-202 | SEMA6A | Q9H2E6 | Semaphorin-6A | chr5 | GO:0016525 | Not Cancer Driver | No | 99 | 0.0961165048543689 | 458 | 49 | 0.0475728155339805 | 0 |
| SERPINF1-201 | SERPINF1 | P36955 | Pigment epithelium-derived factor | chr17 | GO:0016525 | Not Cancer Driver | No | 37 | 0.0885167464114832 | 57 | 5 | 0.0119617224880382 | 0 |
| SPARC-201 | SPARC | P09486 | SPARC | chr5 | GO:0016525 | Not Cancer Driver | No | 39 | 0.1287128712871287 | 70 | 2 | 0.0066006600660066 | 2 |
| SPINK5-201 | SPINK5 | Q9NQ38 | Serine protease inhibitor Kazal-type 5 | chr5 | GO:0016525 | Not Cancer Driver | No | 129 | 0.1212406015037594 | 601 | 90 | 0.0845864661654135 | 0 |
| SPRED1-201 | SPRED1 | Q7Z699 | Sprouty-related, EVH1 domain-containing protein 1 | chr15 | GO:0016525 | Not Cancer Driver | No | 53 | 0.1193693693693693 | 195 | 28 | 0.063063063063063 | 2 |
| SPRY2-202 | SPRY2 | O43597 | Protein sprouty homolog 2 | chr13 | GO:0016525 | Not Cancer Driver | No | 32 | 0.1015873015873015 | 170 | 19 | 0.0603174603174603 | 1 |
| STAB1-201 | STAB1 | Q9NY15 | Stabilin-1 | chr3 | GO:0016525 | Not Cancer Driver | No | 281 | 0.1093385214007782 | 93 | 12 | 0.0046692607003891 | 0 |
| STAT1-201 | STAT1 | P42224 | Signal transducer and activator of transcription 1-alpha/beta | chr2 | GO:0016525 | Not Cancer Driver | No | 100 | 0.1333333333333333 | 144 | 16 | 0.0213333333333333 | 23 |
| SULF1-202 | SULF1 | Q8IWU6 | Extracellular sulfatase Sulf-1 | chr8 | GO:0016525 | Not Cancer Driver | No | 183 | 0.2101033295063145 | 269 | 61 | 0.0700344431687715 | 0 |
| SYNJ2BP-201 | SYNJ2BP | P57105 | Synaptojanin-2-binding protein | chr14 | GO:0016525 | Not Cancer Driver | No | 21 | 0.1448275862068965 | 12 | 1 | 0.0068965517241379 | 0 |
| TEK-201 | TEK | Q02763 | Angiopoietin-1 receptor | chr9 | GO:0016525 | Not Cancer Driver | No | 145 | 0.1290035587188612 | 126 | 13 | 0.0115658362989323 | 9 |
| TGFB2-202 | TGFB2 | P61812 | Transforming growth factor beta-2 proprotein | chr1 | GO:0016525 | Not Cancer Driver | No | 44 | 0.1062801932367149 | 47 | 5 | 0.0120772946859903 | 4 |
| THBS1-201 | THBS1 | P07996 | Thrombospondin-1 | chr15 | GO:0016525 | Not Cancer Driver | No | 153 | 0.1307692307692307 | 321 | 50 | 0.0427350427350427 | 0 |
| THBS2-206 | THBS2 | P35442 | Thrombospondin-2 | chr6 | GO:0016525 | Not Cancer Driver | No | 197 | 0.1680887372013652 | 320 | 53 | 0.0452218430034129 | 0 |
| THBS4-201 | THBS4 | P35443 | Thrombospondin-4 | chr5 | GO:0016525 | Not Cancer Driver | No | 99 | 0.1030176899063475 | 282 | 33 | 0.0343392299687825 | 0 |
| TIE1-201 | TIE1 | P35590 | Tyrosine-protein kinase receptor Tie-1 | chr1 | GO:0016525 | Not Cancer Driver | No | 156 | 0.1370826010544815 | 223 | 36 | 0.031634446397188 | 0 |
| TNMD-201 | TNMD | Q9H2S6 | Tenomodulin | chrX | GO:0016525 | Not Cancer Driver | No | 36 | 0.113564668769716 | 44 | 8 | 0.0252365930599369 | 0 |
| VASH1-201 | VASH1 | Q7L8A9 | Tubulinyl-Tyr carboxypeptidase 1 | chr14 | GO:0016525 | Not Cancer Driver | No | 33 | 0.0904109589041095 | 215 | 14 | 0.0383561643835616 | 0 |
| YJEFN3-203 | YJEFN3 | A6XGL0 | YjeF N-terminal domain-containing protein 3 | chr19 | GO:0016525 | Not Cancer Driver | No | 24 | 0.0802675585284281 | 56 | 2 | 0.0066889632107023 | 0 |