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Total number of protein in "GO:0016605" GO term:  108

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AKAP8L-201 AKAP8L Q9ULX6 A-kinase anchor protein 8-like chr19 GO:0016605 Not Cancer Driver No 57 0.088235294117647 510 44 0.0681114551083591 0
ANKRD2-202 ANKRD2 Q9GZV1 Ankyrin repeat domain-containing protein 2 chr10 GO:0016605 Not Cancer Driver No 25 0.0694444444444444 194 15 0.0416666666666666 0
ATR-201 ATR Q13535 Serine/threonine-protein kinase ATR chr3 GO:0016605 Census, Compendium Yes 261 0.098714069591528 107 11 0.0041603630862329 1
ATRX-201 ATRX P46100 Transcriptional regulator ATRX chrX GO:0016605 Census, Compendium Yes 306 0.1227929373996789 1673 173 0.069422150882825 29
BASP1-201 BASP1 P80723 Brain acid soluble protein 1 chr5 GO:0016605 Not Cancer Driver No 12 0.052863436123348 227 12 0.052863436123348 0
BLM-201 BLM P54132 RecQ-like DNA helicase BLM chr15 GO:0016605 Census Yes 112 0.0790402258292166 671 53 0.0374029640084686 9
BMAL1-203 BMAL1 O00327 Basic helix-loop-helix ARNT-like protein 1 chr11 GO:0016605 Not Cancer Driver No 54 0.0862619808306709 332 31 0.0495207667731629 0
CALCOCO2-201 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 GO:0016605 Not Cancer Driver No 31 0.0695067264573991 213 13 0.0291479820627802 0
CASP8AP2-205 CASP8AP2 Q9UKL3 CASP8-associated protein 2 chr6 GO:0016605 Not Cancer Driver No 0 0.0 1508 0 0.0 0
CBX5-201 CBX5 P45973 Chromobox protein homolog 5 chr12 GO:0016605 Not Cancer Driver No 15 0.0785340314136125 116 8 0.0418848167539267 0
CDK9-201 CDK9 P50750 Cyclin-dependent kinase 9 chr9 GO:0016605 Not Cancer Driver No 40 0.1075268817204301 34 2 0.0053763440860215 0
CHD3-201 CHD3 Q12873 Chromodomain-helicase-DNA-binding protein 3 chr17 GO:0016605 Not Cancer Driver No 187 0.0935 1017 92 0.046 17
CHEK2-206 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 GO:0016605 Census, Compendium Yes 72 0.1325966850828729 157 19 0.0349907918968692 11
CHFR-203 CHFR Q96EP1 E3 ubiquitin-protein ligase CHFR chr12 GO:0016605 Not Cancer Driver No 59 0.0888554216867469 342 37 0.055722891566265 0
CIART-201 CIART Q8N365 Circadian-associated transcriptional repressor chr1 GO:0016605 Not Cancer Driver No 45 0.1168831168831168 274 30 0.0779220779220779 0
CIITA-201 CIITA P33076 MHC class II transactivator chr16 GO:0016605 Census, Compendium Yes 142 0.1256637168141593 320 40 0.0353982300884955 2
CSNK2A1-201 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 GO:0016605 Not Cancer Driver No 47 0.1202046035805626 75 6 0.0153452685421994 4
CSNK2B-203 CSNK2B P67870 Casein kinase II subunit beta chr6 GO:0016605 Not Cancer Driver No 18 0.0837209302325581 19 0 0.0 3
DAPK3-202 DAPK3 O43293 Death-associated protein kinase 3 chr19 GO:0016605 Not Cancer Driver No 45 0.0991189427312775 82 6 0.013215859030837 0
DAXX-202 DAXX Q9UER7 Death domain-associated protein 6 chr6 GO:0016605 Census, Compendium Yes 79 0.1067567567567567 549 57 0.077027027027027 0
EIF3E-201 EIF3E P60228 Eukaryotic translation initiation factor 3 subunit E chr8 GO:0016605 Census, Compendium Yes 59 0.1325842696629213 27 2 0.0044943820224719 0
EIF4ENIF1-201 EIF4ENIF1 Q9NRA8 Eukaryotic translation initiation factor 4E transporter chr22 GO:0016605 Not Cancer Driver No 86 0.0873096446700507 902 75 0.0761421319796954 0
ELF4-201 ELF4 Q99607 ETS-related transcription factor Elf-4 chrX GO:0016605 Census, Compendium Yes 63 0.0950226244343891 487 46 0.0693815987933635 2
GCNA-202 GCNA Q96QF7 Germ cell nuclear acidic protein chrX GO:0016605 Not Cancer Driver No 47 0.0680173661360347 513 22 0.0318379160636758 0
HIPK1-208 HIPK1 Q86Z02 Homeodomain-interacting protein kinase 1 chr1 GO:0016605 Not Cancer Driver No 104 0.0859504132231405 567 58 0.0479338842975206 0
HIPK2-202 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:0016605 Not Cancer Driver No 124 0.1035058430717863 686 76 0.0634390651085141 0
HIPK3-201 HIPK3 Q9H422 Homeodomain-interacting protein kinase 3 chr11 GO:0016605 Not Cancer Driver No 91 0.0748971193415637 559 38 0.031275720164609 0
HIRA-201 HIRA P54198 Protein HIRA chr22 GO:0016605 Not Cancer Driver No 104 0.1022615535889872 289 30 0.0294985250737463 0
HMBOX1-201 HMBOX1 Q6NT76 Homeobox-containing protein 1 chr8 GO:0016605 Not Cancer Driver No 36 0.0857142857142857 319 28 0.0666666666666666 0
HSF1-204 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0016605 Not Cancer Driver No 49 0.0926275992438563 336 30 0.0567107750472589 0
IKBKE-203 IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 GO:0016605 Not Cancer Driver No 90 0.1256983240223463 76 10 0.0139664804469273 0
ISG20-201 ISG20 Q96AZ6 Interferon-stimulated gene 20 kDa protein chr15 GO:0016605 Not Cancer Driver No 17 0.0939226519337016 6 0 0.0 0
KAT6A-201 KAT6A Q92794 Histone acetyltransferase KAT6A chr8 GO:0016605 Census, Compendium Yes 119 0.0593812375249501 1424 67 0.0334331337325349 0
KLHL20-201 KLHL20 Q9Y2M5 Kelch-like protein 20 chr1 GO:0016605 Not Cancer Driver No 64 0.1050903119868637 144 12 0.0197044334975369 0
LRCH4-201 LRCH4 O75427 Leucine-rich repeat and calponin homology domain-containing protein 4 chr7 GO:0016605 Not Cancer Driver No 59 0.0863836017569546 333 34 0.0497803806734992 0
MAGEA2-210 MAGEA2B P43356 Melanoma-associated antigen 2 chrX GO:0016605 Not Cancer Driver No 0 0.0 113 0 0.0 0
MAGEA2B-212 MAGEA2B P43356 Melanoma-associated antigen 2 chrX GO:0016605 Not Cancer Driver No 0 0.0 113 0 0.0 0
MAPK7-204 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:0016605 Not Cancer Driver No 56 0.0686274509803921 490 31 0.0379901960784313 0
MKNK2-201 MKNK2 Q9HBH9 MAP kinase-interacting serine/threonine-protein kinase 2 chr19 GO:0016605 Not Cancer Driver No 30 0.064516129032258 124 5 0.010752688172043 0
MLIP-208 MLIP Q5VWP3 Muscular LMNA-interacting protein chr6 GO:0016605 Not Cancer Driver No 71 0.0715005035246727 924 60 0.0604229607250755 0
MORC3-201 MORC3 Q14149 MORC family CW-type zinc finger protein 3 chr21 GO:0016605 Not Cancer Driver No 75 0.0798722044728434 397 36 0.0383386581469648 0
MRE11-201 MRE11 P49959 Double-strand break repair protein MRE11 chr11 GO:0016605 Not Cancer Driver No 61 0.0861581920903954 292 28 0.03954802259887 1
MTOR-201 MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0016605 Census, Compendium Yes 298 0.1169085916045508 298 28 0.0109846998823067 15
N4BP1-201 N4BP1 O75113 NEDD4-binding protein 1 chr16 GO:0016605 Not Cancer Driver No 71 0.0792410714285714 433 38 0.0424107142857142 0
NBN-201 NBN O60934 Nibrin chr8 GO:0016605 Census Yes 63 0.0835543766578249 420 45 0.059681697612732 1
NFE2-202 NFE2 Q16621 Transcription factor NF-E2 45 kDa subunit chr12 GO:0016605 Not Cancer Driver No 53 0.1420911528150134 295 40 0.1072386058981233 0
NR2C1-202 NR2C1 P13056 Nuclear receptor subfamily 2 group C member 1 chr12 GO:0016605 Not Cancer Driver No 44 0.0729684908789386 157 9 0.0149253731343283 0
NSMCE2-201 NSMCE2 Q96MF7 E3 SUMO-protein ligase NSE2 chr8 GO:0016605 Not Cancer Driver No 18 0.0728744939271255 119 10 0.0404858299595141 0
PARK7-201 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0016605 Not Cancer Driver No 8 0.0423280423280423 30 0 0.0 6
PATL1-201 PATL1 Q86TB9 Protein PAT1 homolog 1 chr11 GO:0016605 Not Cancer Driver No 51 0.0662337662337662 500 31 0.0402597402597402 0
PIAS1-201 PIAS1 O75925 E3 SUMO-protein ligase PIAS1 chr15 GO:0016605 Not Cancer Driver No 48 0.0737327188940092 241 25 0.0384024577572964 0
PIAS2-204 PIAS2 O75928 E3 SUMO-protein ligase PIAS2 chr18 GO:0016605 Not Cancer Driver No 57 0.0917874396135265 209 19 0.0305958132045088 0
PIAS4-201 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 GO:0016605 Not Cancer Driver No 40 0.0784313725490196 143 18 0.0352941176470588 0
PML-201 PML P29590 Protein PML chr15 GO:0016605 Census, Compendium Yes 87 0.0986394557823129 312 28 0.0317460317460317 0
PPARGC1A-201 PPARGC1A Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha chr4 GO:0016605 Not Cancer Driver No 91 0.1140350877192982 613 85 0.106516290726817 0
PTEN-201 PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0016605 Census, Compendium Yes 425 1.054590570719603 76 5 0.0124069478908188 37
RAD51-201 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 GO:0016605 Not Cancer Driver No 27 0.079646017699115 48 3 0.0088495575221238 3
RB1-201 RB1 P06400 Retinoblastoma-associated protein chr13 GO:0016605 Census, Compendium Yes 89 0.0959051724137931 282 26 0.0280172413793103 21
RDM1-228 RDM1 Q8NG50 RAD52 motif-containing protein 1 chr17 GO:0016605 Not Cancer Driver No 24 0.0845070422535211 11 3 0.0105633802816901 0
RFWD3-201 RFWD3 Q6PCD5 E3 ubiquitin-protein ligase RFWD3 chr16 GO:0016605 Census Yes 59 0.0762273901808785 319 26 0.0335917312661498 1
RGS14-201 RGS14 O43566 Regulator of G-protein signaling 14 chr5 GO:0016605 Not Cancer Driver No 46 0.0812720848056537 309 27 0.0477031802120141 0
RNF111-202 RNF111 Q6ZNA4 E3 ubiquitin-protein ligase Arkadia chr15 GO:0016605 Not Cancer Driver No 76 0.0764587525150905 859 65 0.0653923541247484 0
RNF4-201 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 GO:0016605 Not Cancer Driver No 9 0.0473684210526315 120 5 0.0263157894736842 0
RNF6-203 RNF6 Q9Y252 E3 ubiquitin-protein ligase RNF6 chr13 GO:0016605 Compendium Yes 54 0.0788321167883211 607 50 0.072992700729927 0
RPA1-201 RPA1 P27694 Replication protein A 70 kDa DNA-binding subunit chr17 GO:0016605 Not Cancer Driver No 45 0.073051948051948 98 7 0.0113636363636363 1
RPA2-203 RPA2 P15927 Replication protein A 32 kDa subunit chr1 GO:0016605 Not Cancer Driver No 20 0.074074074074074 117 12 0.0444444444444444 0
RPAIN-203 RPAIN Q86UA6 RPA-interacting protein chr17 GO:0016605 Not Cancer Driver No 21 0.0958904109589041 31 4 0.0182648401826484 0
SATB1-201 SATB1 Q01826 DNA-binding protein SATB1 chr3 GO:0016605 Compendium Yes 104 0.1363040629095675 487 63 0.0825688073394495 9
SENP2-201 SENP2 Q9HC62 Sentrin-specific protease 2 chr3 GO:0016605 Not Cancer Driver No 41 0.0696095076400679 285 22 0.0373514431239388 0
SIMC1-205 SIMC1 Q8NDZ2 SUMO-interacting motif-containing protein 1 chr5 GO:0016605 Not Cancer Driver No 40 0.0458715596330275 494 5 0.0057339449541284 0
SIRT1-201 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0016605 Not Cancer Driver No 43 0.0575635876840696 435 19 0.0254350736278447 0
SKI-201 SKI P12755 Ski oncogene chr1 GO:0016605 Census Yes 41 0.0563186813186813 434 27 0.037087912087912 8
SLF2-201 SLF2 Q8IX21 SMC5-SMC6 complex localization factor protein 2 chr10 GO:0016605 Not Cancer Driver No 83 0.0707587382779198 726 58 0.0494458653026428 1
SMC5-201 SMC5 Q8IY18 Structural maintenance of chromosomes protein 5 chr9 GO:0016605 Not Cancer Driver No 94 0.0853769300635785 381 35 0.0317892824704813 1
SMC6-207 SMC6 Q96SB8 Structural maintenance of chromosomes protein 6 chr2 GO:0016605 Not Cancer Driver No 95 0.0870760769935838 459 43 0.0394133822181484 0
SP100-201 SP100 P23497 Nuclear autoantigen Sp-100 chr2 GO:0016605 Not Cancer Driver No 76 0.08646188850967 683 61 0.0693970420932878 0
SP140-203 SP140 Q13342 Nuclear body protein SP140 chr2 GO:0016605 Compendium Yes 151 0.1741637831603229 462 96 0.1107266435986159 0
SP3-201 SP3 Q02447 Transcription factor Sp3 chr2 GO:0016605 Not Cancer Driver No 50 0.0640204865556978 588 34 0.0435339308578745 0
SPN-206 SPN P16150 Leukosialin chr16 GO:0016605 Not Cancer Driver No 37 0.0925 359 29 0.0725 0
SPTBN4-210 SPTBN4 Q9H254 Spectrin beta chain, non-erythrocytic 4 chr19 GO:0016605 Not Cancer Driver No 264 0.1029641185647426 871 75 0.0292511700468018 0
SQSTM1-202 SQSTM1 Q13501 Sequestosome-1 chr5 GO:0016605 Not Cancer Driver No 41 0.0931818181818181 271 24 0.0545454545454545 30
SRSF2-202 SRSF2 Q01130 Serine/arginine-rich splicing factor 2 chr17 GO:0016605 Census, Compendium Yes 16 0.0723981900452488 221 16 0.0723981900452488 0
SUMO1-203 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 GO:0016605 Not Cancer Driver No 10 0.099009900990099 76 7 0.0693069306930693 0
SUMO2-202 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 GO:0016605 Not Cancer Driver No 8 0.0842105263157894 70 6 0.0631578947368421 0
SUMO3-201 SUMO3 P55854 Small ubiquitin-related modifier 3 chr21 GO:0016605 Not Cancer Driver No 6 0.058252427184466 86 4 0.0388349514563106 0
TCF7L2-206 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 GO:0016605 Census, Compendium Yes 76 0.122778675282714 517 62 0.1001615508885298 0
TDG-202 TDG Q13569 G/T mismatch-specific thymine DNA glycosylase chr12 GO:0016605 Not Cancer Driver No 45 0.1097560975609756 186 21 0.0512195121951219 0
TDP2-202 TDP2 O95551 Tyrosyl-DNA phosphodiesterase 2 chr6 GO:0016605 Not Cancer Driver No 38 0.1049723756906077 80 4 0.011049723756906 0
TENM2-203 TENM2 Q9NT68 Teneurin-2 chr5 GO:0016605 Not Cancer Driver No 385 0.138788752703677 524 63 0.0227108868060562 0
TERT-201 TERT O14746 Telomerase reverse transcriptase chr5 GO:0016605 Census Yes 86 0.0759717314487632 213 11 0.0097173144876325 32
THAP1-201 THAP1 Q9NVV9 THAP domain-containing protein 1 chr8 GO:0016605 Not Cancer Driver No 11 0.0516431924882629 76 4 0.0187793427230046 40
TOP3A-201 TOP3A Q13472 DNA topoisomerase 3-alpha chr17 GO:0016605 Not Cancer Driver No 79 0.0789210789210789 293 28 0.0279720279720279 2
TOPBP1-201 TOPBP1 Q92547 DNA topoisomerase 2-binding protein 1 chr3 GO:0016605 Not Cancer Driver No 121 0.0795006570302234 579 43 0.0282522996057818 0
TOPORS-201 TOPORS Q9NS56 E3 ubiquitin-protein ligase Topors chr9 GO:0016605 Not Cancer Driver No 62 0.0593301435406698 796 38 0.0363636363636363 0
TP53-201 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0016605 Census, Compendium Yes 2742 6.977099236641221 282 1364 3.470737913486005 60
TP53INP1-201 TP53INP1 Q96A56 Tumor protein p53-inducible nuclear protein 1 chr8 GO:0016605 Not Cancer Driver No 21 0.0875 134 12 0.05 0
TP53INP2-202 TP53INP2 Q8IXH6 Tumor protein p53-inducible nuclear protein 2 chr20 GO:0016605 Not Cancer Driver No 17 0.0772727272727272 198 15 0.0681818181818181 0
TRIM16-226 TRIM16 O95361 Tripartite motif-containing protein 16 chr17 GO:0016605 Not Cancer Driver No 49 0.0868794326241134 132 5 0.0088652482269503 0
TRIM27-202 TRIM27 P14373 Zinc finger protein RFP chr6 GO:0016605 Census Yes 46 0.0896686159844054 87 9 0.0175438596491228 0
TRIM8-209 TRIM8 Q9BZR9 E3 ubiquitin-protein ligase TRIM8 chr10 GO:0016605 Not Cancer Driver No 52 0.0943738656987295 209 23 0.0417422867513611 0
UBE2I-203 UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 GO:0016605 Not Cancer Driver No 16 0.1012658227848101 16 3 0.0189873417721519 0
UBN1-201 UBN1 Q9NPG3 Ubinuclein-1 chr16 GO:0016605 Not Cancer Driver No 96 0.0846560846560846 944 84 0.074074074074074 0
USP7-201 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 GO:0016605 Not Cancer Driver No 135 0.1225045372050816 215 34 0.0308529945553539 7
WDFY3-201 WDFY3 Q8IZQ1 WD repeat and FYVE domain-containing protein 3 chr4 GO:0016605 Not Cancer Driver No 352 0.0998298355076574 605 62 0.0175836642087351 1
ZBED1-206 ZBED1 O96006 E3 SUMO-protein ligase ZBED1 chrX GO:0016605 Not Cancer Driver No 88 0.1268011527377521 97 7 0.0100864553314121 0
ZBTB16-201 ZBTB16 Q05516 Zinc finger and BTB domain-containing protein 16 chr11 GO:0016605 Census, Compendium Yes 105 0.1560178306092124 268 42 0.0624071322436849 1
ZMYM2-210 ZMYM2 Q9UBW7 Zinc finger MYM-type protein 2 chr13 GO:0016605 Census Yes 105 0.0762527233115468 583 47 0.0341321713870733 0
ZNF451-203 ZNF451 Q9Y4E5 E3 SUMO-protein ligase ZNF451 chr6 GO:0016605 Not Cancer Driver No 114 0.1074458058435438 191 19 0.0179076343072573 0