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Total number of protein in "GO:0017124" GO term:  119

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABI1-207 ABI1 Q8IZP0 Abl interactor 1 chr10 GO:0017124 Census, Compendium Yes 37 0.0728346456692913 360 28 0.0551181102362204 0
ABI2-203 ABI2 Q9NYB9 Abl interactor 2 chr2 GO:0017124 Not Cancer Driver No 46 0.084870848708487 377 30 0.055350553505535 0
ABI3-201 ABI3 Q9P2A4 ABI gene family member 3 chr17 GO:0017124 Not Cancer Driver No 36 0.0983606557377049 249 23 0.0628415300546448 0
ABL1-201 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0017124 Census, Compendium Yes 106 0.0938053097345132 609 53 0.0469026548672566 2
ADAM10-201 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 GO:0017124 Not Cancer Driver No 73 0.0975935828877005 156 18 0.0240641711229946 4
ADAM12-202 ADAM12 O43184 Disintegrin and metalloproteinase domain-containing protein 12 chr10 GO:0017124 Not Cancer Driver No 123 0.1353135313531353 206 33 0.0363036303630363 0
ADAM15-203 ADAM15 Q13444 Disintegrin and metalloproteinase domain-containing protein 15 chr1 GO:0017124 Not Cancer Driver No 76 0.0880648899188876 215 23 0.0266512166859791 0
ADAM17-201 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0017124 Not Cancer Driver No 63 0.0764563106796116 182 17 0.020631067961165 0
ADAM19-203 ADAM19 Q9H013 Disintegrin and metalloproteinase domain-containing protein 19 chr5 GO:0017124 Not Cancer Driver No 144 0.1507853403141361 372 61 0.0638743455497382 0
ADAM9-209 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 GO:0017124 Not Cancer Driver No 59 0.072039072039072 130 7 0.0085470085470085 0
AFAP1-201 AFAP1 Q8N556 Actin filament-associated protein 1 chr4 GO:0017124 Not Cancer Driver No 64 0.0876712328767123 489 37 0.0506849315068493 0
AFAP1L1-201 AFAP1L1 Q8TED9 Actin filament-associated protein 1-like 1 chr5 GO:0017124 Not Cancer Driver No 86 0.1119791666666666 403 43 0.0559895833333333 0
AFAP1L2-201 AFAP1L2 Q8N4X5 Actin filament-associated protein 1-like 2 chr10 GO:0017124 Not Cancer Driver No 74 0.0904645476772616 564 54 0.0660146699266503 0
AKAP5-202 AKAP5 P24588 A-kinase anchor protein 5 chr14 GO:0017124 Not Cancer Driver No 24 0.0562060889929742 409 21 0.0491803278688524 0
ARHGAP1-201 ARHGAP1 Q07960 Rho GTPase-activating protein 1 chr11 GO:0017124 Not Cancer Driver No 29 0.0660592255125284 91 6 0.0136674259681093 0
ARHGAP17-201 ARHGAP17 Q68EM7 Rho GTPase-activating protein 17 chr16 GO:0017124 Not Cancer Driver No 68 0.0771850170261067 547 35 0.039727582292849 0
ARHGAP27-219 ARHGAP27 Q6ZUM4 Rho GTPase-activating protein 27 chr17 GO:0017124 Not Cancer Driver No 66 0.0742407199100112 517 43 0.0483689538807649 0
ARHGAP31-201 ARHGAP31 Q2M1Z3 Rho GTPase-activating protein 31 chr3 GO:0017124 Not Cancer Driver No 206 0.1426592797783933 1174 176 0.1218836565096952 0
ARHGAP6-202 ARHGAP6 O43182 Rho GTPase-activating protein 6 chrX GO:0017124 Not Cancer Driver No 124 0.1273100616016427 681 88 0.0903490759753593 0
BCAR1-201 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 GO:0017124 Not Cancer Driver No 88 0.1011494252873563 681 64 0.0735632183908046 0
CABYR-216 CABYR O75952 Calcium-binding tyrosine phosphorylation-regulated protein chr18 GO:0017124 Not Cancer Driver No 14 0.0283975659229208 377 8 0.0162271805273833 0
CASP9-201 CASP9 P55211 Caspase-9 chr1 GO:0017124 Census Yes 26 0.0625 71 7 0.016826923076923 0
CBL-201 CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0017124 Census, Compendium Yes 84 0.0927152317880794 513 44 0.0485651214128035 4
CBLB-201 CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 GO:0017124 Census Yes 126 0.1283095723014256 565 77 0.0784114052953156 0
CBLC-203 CBLC Q9ULV8 E3 ubiquitin-protein ligase CBL-C chr19 GO:0017124 Census Yes 43 0.090717299578059 126 12 0.0253164556962025 0
CCDC6-201 CCDC6 Q16204 Coiled-coil domain-containing protein 6 chr10 GO:0017124 Census, Compendium Yes 48 0.1012658227848101 373 40 0.0843881856540084 0
CD2AP-201 CD2AP Q9Y5K6 CD2-associated protein chr6 GO:0017124 Not Cancer Driver No 51 0.0798122065727699 458 38 0.0594679186228482 0
CD3E-201 CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 GO:0017124 Not Cancer Driver No 16 0.0772946859903381 72 6 0.0289855072463768 0
CIT-201 CIT O14578 Citron Rho-interacting kinase chr12 GO:0017124 Not Cancer Driver No 196 0.0966946225949679 1020 116 0.0572274296990626 3
CNTNAP1-201 CNTNAP1 P78357 Contactin-associated protein 1 chr17 GO:0017124 Not Cancer Driver No 131 0.0946531791907514 141 15 0.0108381502890173 6
CRB3-204 CRB3 Q9BUF7 Protein crumbs homolog 3 chr19 GO:0017124 Not Cancer Driver No 8 0.0666666666666666 53 4 0.0333333333333333 0
CRK-201 CRK P46108 Adapter molecule crk chr17 GO:0017124 Not Cancer Driver No 24 0.0789473684210526 197 19 0.0625 0
CTTNBP2-201 CTTNBP2 Q8WZ74 Cortactin-binding protein 2 chr7 GO:0017124 Not Cancer Driver No 186 0.1118460613349368 864 100 0.0601322910402886 0
CYBA-201 CYBA P13498 Cytochrome b-245 light chain chr16 GO:0017124 Not Cancer Driver No 17 0.0871794871794871 66 1 0.0051282051282051 10
DAB2IP-203 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0017124 Not Cancer Driver No 95 0.0798990748528175 682 49 0.04121110176619 0
DNAJC6-203 DNAJC6 O75061 Putative tyrosine-protein phosphatase auxilin chr1 GO:0017124 Not Cancer Driver No 104 0.1139101861993428 456 57 0.0624315443592552 1
DNM2-201 DNM2 P50570 Dynamin-2 chr19 GO:0017124 Census Yes 95 0.1091954022988505 271 32 0.0367816091954023 16
DOCK1-201 DOCK1 Q14185 Dedicator of cytokinesis protein 1 chr10 GO:0017124 Not Cancer Driver No 168 0.0900804289544235 356 37 0.0198391420911528 0
DOCK3-201 DOCK3 Q8IZD9 Dedicator of cytokinesis protein 3 chr3 GO:0017124 Not Cancer Driver No 269 0.1325123152709359 458 51 0.0251231527093596 0
DOCK4-206 DOCK4 Q8N1I0 Dedicator of cytokinesis protein 4 chr7 GO:0017124 Not Cancer Driver No 258 0.1312309257375381 398 67 0.0340793489318413 0
DPYSL3-202 DPYSL3 Q14195 Dihydropyrimidinase-related protein 3 chr5 GO:0017124 Not Cancer Driver No 65 0.1140350877192982 129 11 0.019298245614035 0
DRD4-201 DRD4 P21917 D(4) dopamine receptor chr11 GO:0017124 Not Cancer Driver No 15 0.035799522673031 109 0 0.0 0
DTX1-204 DTX1 Q86Y01 E3 ubiquitin-protein ligase DTX1 chr12 GO:0017124 Compendium Yes 78 0.1258064516129032 304 34 0.0548387096774193 0
EFS-201 EFS O43281 Embryonal Fyn-associated substrate chr14 GO:0017124 Not Cancer Driver No 52 0.0926916221033868 416 36 0.0641711229946524 0
ELMO1-201 ELMO1 Q92556 Engulfment and cell motility protein 1 chr7 GO:0017124 Not Cancer Driver No 158 0.2173314993122421 98 21 0.0288858321870701 0
ELMO2-201 ELMO2 Q96JJ3 Engulfment and cell motility protein 2 chr20 GO:0017124 Not Cancer Driver No 69 0.0958333333333333 102 11 0.0152777777777777 0
ELMO3-202 ELMO3 Q96BJ8 Engulfment and cell motility protein 3 chr16 GO:0017124 Not Cancer Driver No 52 0.0722222222222222 115 9 0.0125 0
ENAH-204 ENAH Q8N8S7 Protein enabled homolog chr1 GO:0017124 Not Cancer Driver No 27 0.0456852791878172 514 27 0.0456852791878172 0
ENKUR-201 ENKUR Q8TC29 Enkurin chr10 GO:0017124 Not Cancer Driver No 31 0.12109375 158 21 0.08203125 0
EPS15-203 EPS15 P42566 Epidermal growth factor receptor substrate 15 chr1 GO:0017124 Census, Compendium Yes 74 0.0825892857142857 544 47 0.0524553571428571 0
ESPN-216 ESPN B1AK53 Espin chr1 GO:0017124 Not Cancer Driver No 55 0.0644028103044496 605 50 0.0585480093676815 2
EVL-202 EVL Q9UI08 Ena/VASP-like protein chr14 GO:0017124 Not Cancer Driver No 39 0.09375 339 34 0.0817307692307692 0
FMN1-211 FMN1 Q68DA7 Formin-1 chr15 GO:0017124 Not Cancer Driver No 26 0.018322762508809 996 24 0.0169133192389006 0
FUT8-216 FUT8 Q9BYC5 Alpha-(1,6)-fucosyltransferase chr14 GO:0017124 Not Cancer Driver No 55 0.0956521739130434 81 17 0.0295652173913043 1
GPX1-202 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:0017124 Not Cancer Driver No 22 0.1083743842364532 12 3 0.0147783251231527 0
GRB2-202 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 GO:0017124 Not Cancer Driver No 21 0.0967741935483871 10 0 0.0 0
HCLS1-201 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 GO:0017124 Not Cancer Driver No 81 0.1666666666666666 448 75 0.1543209876543209 0
HIP1R-201 HIP1R O75146 Huntingtin-interacting protein 1-related protein chr12 GO:0017124 Not Cancer Driver No 73 0.0683520599250936 527 30 0.0280898876404494 0
INPP5D-204 INPP5D Q92835 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 chr2 GO:0017124 Not Cancer Driver No 140 0.1177460050462573 579 75 0.0630782169890664 0
INPP5J-201 INPP5J Q15735 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A chr22 GO:0017124 Not Cancer Driver No 57 0.0566600397614314 632 17 0.0168986083499005 0
INPPL1-201 INPPL1 O15357 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 chr11 GO:0017124 Not Cancer Driver No 146 0.1160572337042925 567 66 0.0524642289348171 4
ITGB1BP2-201 ITGB1BP2 Q9UKP3 Integrin beta-1-binding protein 2 chrX GO:0017124 Not Cancer Driver No 40 0.1152737752161383 137 14 0.0403458213256484 0
KHDRBS1-202 KHDRBS1 Q07666 KH domain-containing, RNA-binding, signal transduction-associated protein 1 chr1 GO:0017124 Not Cancer Driver No 42 0.0948081264108352 362 37 0.0835214446952596 0
KHDRBS2-201 KHDRBS2 Q5VWX1 KH domain-containing, RNA-binding, signal transduction-associated protein 2 chr6 GO:0017124 Not Cancer Driver No 137 0.3925501432664756 270 114 0.326647564469914 0
KHDRBS3-201 KHDRBS3 O75525 KH domain-containing, RNA-binding, signal transduction-associated protein 3 chr8 GO:0017124 Not Cancer Driver No 51 0.1473988439306358 230 32 0.0924855491329479 0
LANCL1-207 LANCL1 O43813 Glutathione S-transferase LANCL1 chr2 GO:0017124 Not Cancer Driver No 31 0.0776942355889724 10 0 0.0 0
LRP2-205 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0017124 Not Cancer Driver No 740 0.158968850698174 209 26 0.0055853920515574 1
LYN-202 LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0017124 Census Yes 78 0.15234375 85 10 0.01953125 0
MAPK15-201 MAPK15 Q8TD08 Mitogen-activated protein kinase 15 chr8 GO:0017124 Not Cancer Driver No 66 0.1213235294117647 236 32 0.0588235294117647 0
MAPT-212 MAPT P10636 Microtubule-associated protein tau chr17 GO:0017124 Not Cancer Driver No 100 0.1319261213720316 750 99 0.1306068601583113 17
MICAL1-202 MICAL1 Q8TDZ2 [F-actin]-monooxygenase MICAL1 chr6 GO:0017124 Not Cancer Driver No 91 0.0852858481724461 365 30 0.0281162136832239 0
MVB12A-201 MVB12A Q96EY5 Multivesicular body subunit 12A chr19 GO:0017124 Not Cancer Driver No 27 0.0989010989010989 67 4 0.0146520146520146 0
MYPN-202 MYPN Q86TC9 Myopalladin chr10 GO:0017124 Not Cancer Driver No 196 0.1484848484848485 935 137 0.1037878787878787 17
NCF1-201 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:0017124 Not Cancer Driver No 31 0.0794871794871794 181 11 0.0282051282051282 1
NCKIPSD-201 NCKIPSD Q9NZQ3 NCK-interacting protein with SH3 domain chr3 GO:0017124 Census Yes 53 0.0734072022160664 260 23 0.0318559556786703 0
NOXA1-203 NOXA1 Q86UR1 NADPH oxidase activator 1 chr9 GO:0017124 Not Cancer Driver No 22 0.0462184873949579 216 15 0.0315126050420168 0
OSTF1-201 OSTF1 Q92882 Osteoclast-stimulating factor 1 chr9 GO:0017124 Not Cancer Driver No 13 0.0607476635514018 51 2 0.0093457943925233 0
PAK3-201 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0017124 Not Cancer Driver No 95 0.1699463327370304 286 48 0.0858676207513416 2
PLSCR1-201 PLSCR1 O15162 Phospholipid scramblase 1 chr3 GO:0017124 Not Cancer Driver No 28 0.0880503144654088 94 11 0.0345911949685534 0
PLSCR3-213 PLSCR3 Q9NRY6 Phospholipid scramblase 3 chr17 GO:0017124 Not Cancer Driver No 19 0.0644067796610169 62 3 0.0101694915254237 0
PLSCR4-201 PLSCR4 Q9NRQ2 Phospholipid scramblase 4 chr3 GO:0017124 Not Cancer Driver No 54 0.1641337386018237 111 9 0.0273556231003039 0
PRKN-206 PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0017124 Not Cancer Driver No 96 0.2064516129032258 78 14 0.0301075268817204 30
PTPN12-201 PTPN12 Q05209 Tyrosine-protein phosphatase non-receptor type 12 chr7 GO:0017124 Not Cancer Driver No 68 0.0871794871794871 518 40 0.0512820512820512 0
PTPN22-201 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0017124 Not Cancer Driver No 107 0.1325898389095415 344 44 0.0545229244114002 4
PTPN6-201 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0017124 Census, Compendium Yes 52 0.0873949579831932 194 20 0.0336134453781512 0
PTTG1-201 PTTG1 O95997 Securin chr5 GO:0017124 Not Cancer Driver No 10 0.0495049504950495 141 4 0.0198019801980198 0
QKI-203 QKI Q96PU8 KH domain-containing RNA-binding protein QKI chr6 GO:0017124 Census, Compendium Yes 43 0.126099706744868 176 22 0.064516129032258 0
RAD9A-201 RAD9A Q99638 Cell cycle checkpoint control protein RAD9A chr11 GO:0017124 Not Cancer Driver No 32 0.0818414322250639 136 7 0.0179028132992327 0
RAPGEF1-201 RAPGEF1 Q13905 Rap guanine nucleotide exchange factor 1 chr9 GO:0017124 Not Cancer Driver No 119 0.1104921077065923 588 66 0.0612813370473537 0
REPS1-208 REPS1 Q96D71 RalBP1-associated Eps domain-containing protein 1 chr6 GO:0017124 Not Cancer Driver No 50 0.0628140703517587 607 41 0.0515075376884422 2
RUFY1-201 RUFY1 Q96T51 RUN and FYVE domain-containing protein 1 chr5 GO:0017124 Not Cancer Driver No 57 0.0805084745762711 358 29 0.0409604519774011 0
RUFY2-213 RUFY2 Q8WXA3 RUN and FYVE domain-containing protein 2 chr10 GO:0017124 Not Cancer Driver No 48 0.0792079207920792 182 16 0.0264026402640264 0
SGIP1-203 SGIP1 Q9BQI5 SH3-containing GRB2-like protein 3-interacting protein 1 chr1 GO:0017124 Not Cancer Driver No 168 0.2028985507246377 563 127 0.1533816425120772 0
SH2D2A-202 SH2D2A Q9NP31 SH2 domain-containing protein 2A chr1 GO:0017124 Not Cancer Driver No 37 0.0951156812339331 272 30 0.0771208226221079 0
SH3BGRL-201 SH3BGRL O75368 Adapter SH3BGRL chrX GO:0017124 Not Cancer Driver No 17 0.1491228070175438 51 7 0.0614035087719298 0
SH3BGRL2-201 SH3BGRL2 Q9UJC5 SH3 domain-binding glutamic acid-rich-like protein 2 chr6 GO:0017124 Not Cancer Driver No 13 0.1214953271028037 27 8 0.0747663551401869 0
SH3BP1-210 SH3BP1 Q9Y3L3 SH3 domain-binding protein 1 chr22 GO:0017124 Not Cancer Driver No 50 0.0713266761768901 438 33 0.0470756062767475 0
SH3BP2-206 SH3BP2 P78314 SH3 domain-binding protein 2 chr4 GO:0017124 Not Cancer Driver No 52 0.0926916221033868 356 32 0.0570409982174688 3
SH3BP5-202 SH3BP5 O60239 SH3 domain-binding protein 5 chr3 GO:0017124 Not Cancer Driver No 33 0.0725274725274725 380 23 0.0505494505494505 0
SH3KBP1-205 SH3KBP1 Q96B97 SH3 domain-containing kinase-binding protein 1 chrX GO:0017124 Not Cancer Driver No 65 0.0977443609022556 532 49 0.0736842105263157 0
SHANK1-201 SHANK1 Q9Y566 SH3 and multiple ankyrin repeat domains protein 1 chr19 GO:0017124 Not Cancer Driver No 228 0.1055067098565478 1668 152 0.0703378065710319 0
SHANK2-214 SHANK2 Q9UPX8 SH3 and multiple ankyrin repeat domains protein 2 chr11 GO:0017124 Not Cancer Driver No 239 0.1292590589507842 1385 210 0.1135749053542455 0
SHANK3-201 SHANK3 Q9BYB0 SH3 and multiple ankyrin repeat domains protein 3 chr22 GO:0017124 Not Cancer Driver No 98 0.0609831985065339 1257 68 0.0423148724331051 3
SIRPA-202 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 GO:0017124 Census, Compendium Yes 60 0.119047619047619 282 41 0.0813492063492063 0
SKAP1-201 SKAP1 Q86WV1 Src kinase-associated phosphoprotein 1 chr17 GO:0017124 Not Cancer Driver No 58 0.1615598885793872 132 24 0.0668523676880222 0
SOCS7-205 SOCS7 O14512 Suppressor of cytokine signaling 7 chr17 GO:0017124 Not Cancer Driver No 33 0.0567986230636833 396 22 0.0378657487091222 0
SOS1-202 SOS1 Q07889 Son of sevenless homolog 1 chr2 GO:0017124 Compendium Yes 155 0.1162790697674418 459 47 0.0352588147036759 32
SYNGAP1-229 SYNGAP1 Q96PV0 Ras/Rap GTPase-activating protein SynGAP chr6 GO:0017124 Not Cancer Driver No 113 0.0841399851079672 833 66 0.0491437081161578 4
SYNJ1-213 SYNJ1 O43426 Synaptojanin-1 chr21 GO:0017124 Not Cancer Driver No 152 0.0966306420851875 585 60 0.0381436745073108 3
SYNJ2-201 SYNJ2 O15056 Synaptojanin-2 chr6 GO:0017124 Not Cancer Driver No 134 0.0895721925133689 548 56 0.0374331550802139 0
TOM1L1-221 TOM1L1 O75674 TOM1-like protein 1 chr17 GO:0017124 Not Cancer Driver No 44 0.0924369747899159 269 28 0.0588235294117647 0
TP53BP2-201 TP53BP2 Q13625 Apoptosis-stimulating of p53 protein 2 chr1 GO:0017124 Not Cancer Driver No 106 0.0934744268077601 866 83 0.0731922398589065 0
USP8-201 USP8 P40818 Ubiquitin carboxyl-terminal hydrolase 8 chr15 GO:0017124 Census, Compendium Yes 82 0.073345259391771 603 49 0.0438282647584973 0
UVRAG-201 UVRAG Q9P2Y5 UV radiation resistance-associated gene protein chr11 GO:0017124 Not Cancer Driver No 58 0.0829756795422031 243 21 0.0300429184549356 0
VASP-201 VASP P50552 Vasodilator-stimulated phosphoprotein chr19 GO:0017124 Not Cancer Driver No 16 0.0421052631578947 335 11 0.0289473684210526 0
WAS-201 WAS P42768 Actin nucleation-promoting factor WAS chrX GO:0017124 Census, Compendium Yes 44 0.0876494023904382 400 28 0.0557768924302788 28
WASF2-202 WASF2 Q9Y6W5 Actin-binding protein WASF2 chr1 GO:0017124 Not Cancer Driver No 36 0.072289156626506 400 22 0.0441767068273092 0
WIPF1-217 WIPF1 O43516 WAS/WASL-interacting protein family member 1 chr2 GO:0017124 Not Cancer Driver No 88 0.1749502982107356 505 88 0.1749502982107356 0
ZNF106-201 ZNF106 Q9H2Y7 Zinc finger protein 106 chr15 GO:0017124 Not Cancer Driver No 115 0.0610727562400424 1494 87 0.046202867764206 0