Total number of protein in "GO:0019903" GO term: 87
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AMBRA1-213 | AMBRA1 | Q9C0C7 | Activating molecule in BECN1-regulated autophagy protein 1 | chr11 | GO:0019903 | Not Cancer Driver | No | 132 | 0.1016949152542373 | 790 | 80 | 0.061633281972265 | 0 |
| ANAPC4-201 | ANAPC4 | Q9UJX5 | Anaphase-promoting complex subunit 4 | chr4 | GO:0019903 | Not Cancer Driver | No | 48 | 0.0594059405940594 | 54 | 0 | 0.0 | 0 |
| ANAPC5-201 | ANAPC5 | Q9UJX4 | Anaphase-promoting complex subunit 5 | chr12 | GO:0019903 | Not Cancer Driver | No | 71 | 0.0940397350993377 | 41 | 1 | 0.0013245033112582 | 0 |
| ANAPC7-203 | ANAPC7 | Q9UJX3 | Anaphase-promoting complex subunit 7 | chr12 | GO:0019903 | Not Cancer Driver | No | 60 | 0.1061946902654867 | 98 | 12 | 0.0212389380530973 | 0 |
| ANK1-205 | ANK1 | P16157 | Ankyrin-1 | chr8 | GO:0019903 | Census | Yes | 315 | 0.1674641148325359 | 813 | 131 | 0.0696438064859117 | 3 |
| AP3B1-201 | AP3B1 | O00203 | AP-3 complex subunit beta-1 | chr5 | GO:0019903 | Not Cancer Driver | No | 91 | 0.083180987202925 | 317 | 22 | 0.0201096892138939 | 1 |
| BAD-201 | BAD | Q92934 | Bcl2-associated agonist of cell death | chr11 | GO:0019903 | Not Cancer Driver | No | 10 | 0.0595238095238095 | 165 | 10 | 0.0595238095238095 | 0 |
| CADM4-201 | CADM4 | Q8NFZ8 | Cell adhesion molecule 4 | chr19 | GO:0019903 | Not Cancer Driver | No | 40 | 0.1030927835051546 | 94 | 9 | 0.0231958762886597 | 0 |
| CD22-201 | CD22 | P20273 | B-cell receptor CD22 | chr19 | GO:0019903 | Not Cancer Driver | No | 126 | 0.1487603305785124 | 293 | 50 | 0.0590318772136954 | 0 |
| CD33-201 | CD33 | P20138 | Myeloid cell surface antigen CD33 | chr19 | GO:0019903 | Not Cancer Driver | No | 84 | 0.2307692307692307 | 184 | 39 | 0.1071428571428571 | 0 |
| CDC27-201 | CDC27 | P30260 | Cell division cycle protein 27 homolog | chr17 | GO:0019903 | Not Cancer Driver | No | 70 | 0.0849514563106796 | 289 | 26 | 0.0315533980582524 | 0 |
| CDH2-201 | CDH2 | P19022 | Cadherin-2 | chr18 | GO:0019903 | Not Cancer Driver | No | 182 | 0.2008830022075055 | 464 | 107 | 0.1181015452538631 | 7 |
| CDH5-201 | CDH5 | P33151 | Cadherin-5 | chr16 | GO:0019903 | Not Cancer Driver | No | 121 | 0.1543367346938775 | 305 | 44 | 0.0561224489795918 | 0 |
| CDKN1B-201 | CDKN1B | P46527 | Cyclin-dependent kinase inhibitor 1B | chr12 | GO:0019903 | Census, Compendium | Yes | 14 | 0.0707070707070707 | 199 | 14 | 0.0707070707070707 | 0 |
| CEACAM1-201 | CEACAM1 | P13688 | Carcinoembryonic antigen-related cell adhesion molecule 1 | chr19 | GO:0019903 | Not Cancer Driver | No | 42 | 0.0798479087452471 | 242 | 14 | 0.026615969581749 | 0 |
| CLEC12B-201 | CLEC12B | Q2HXU8 | C-type lectin domain family 12 member B | chr12 | GO:0019903 | Not Cancer Driver | No | 21 | 0.0760869565217391 | 57 | 4 | 0.0144927536231884 | 0 |
| CSF1R-210 | CSF1R | P07333 | Macrophage colony-stimulating factor 1 receptor | chr5 | GO:0019903 | Census | Yes | 101 | 0.1039094650205761 | 124 | 12 | 0.0123456790123456 | 20 |
| CSK-201 | CSK | P41240 | Tyrosine-protein kinase CSK | chr15 | GO:0019903 | Not Cancer Driver | No | 37 | 0.0822222222222222 | 18 | 1 | 0.0022222222222222 | 0 |
| CTNNB1-201 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | GO:0019903 | Census, Compendium | Yes | 363 | 0.4647887323943662 | 288 | 291 | 0.3725992317541613 | 11 |
| DLG4-202 | DLG4 | P78352 | Disks large homolog 4 | chr17 | GO:0019903 | Not Cancer Driver | No | 74 | 0.1022099447513812 | 233 | 34 | 0.0469613259668508 | 0 |
| EGFR-201 | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:0019903 | Census, Compendium | Yes | 346 | 0.2859504132231405 | 223 | 30 | 0.024793388429752 | 1 |
| EIF2AK3-201 | EIF2AK3 | Q9NZJ5 | Eukaryotic translation initiation factor 2-alpha kinase 3 | chr2 | GO:0019903 | Not Cancer Driver | No | 102 | 0.0913978494623656 | 411 | 37 | 0.0331541218637992 | 1 |
| ENST00000593731 | PIK3R2 | O00459 | Phosphatidylinositol 3-kinase regulatory subunit beta | chr19 | GO:0019903 | Not Cancer Driver | No | 83 | 0.114010989010989 | 418 | 40 | 0.0549450549450549 | 3 |
| FBXL2-216 | FBXL2 | Q9UKC9 | F-box/LRR-repeat protein 2 | chr3 | GO:0019903 | Not Cancer Driver | No | 31 | 0.0732860520094562 | 0 | 0 | 0.0 | 0 |
| FCRL2-201 | FCRL2 | Q96LA5 | Fc receptor-like protein 2 | chr1 | GO:0019903 | Not Cancer Driver | No | 91 | 0.1791338582677165 | 77 | 6 | 0.0118110236220472 | 0 |
| FCRL3-201 | FCRL3 | Q96P31 | Fc receptor-like protein 3 | chr1 | GO:0019903 | Not Cancer Driver | No | 165 | 0.2247956403269754 | 215 | 38 | 0.0517711171662125 | 0 |
| FCRL6-203 | FCRL6 | Q6DN72 | Fc receptor-like protein 6 | chr1 | GO:0019903 | Not Cancer Driver | No | 74 | 0.1705069124423963 | 159 | 25 | 0.0576036866359447 | 0 |
| FLT4-201 | FLT4 | P35916 | Vascular endothelial growth factor receptor 3 | chr5 | GO:0019903 | Census, Compendium | Yes | 203 | 0.1489361702127659 | 259 | 33 | 0.0242112986060161 | 14 |
| GHR-201 | GHR | P10912 | Growth hormone receptor | chr5 | GO:0019903 | Not Cancer Driver | No | 139 | 0.2178683385579937 | 229 | 59 | 0.0924764890282131 | 19 |
| GRB2-202 | GRB2 | P62993 | Growth factor receptor-bound protein 2 | chr17 | GO:0019903 | Not Cancer Driver | No | 21 | 0.0967741935483871 | 10 | 0 | 0.0 | 0 |
| GTF2F1-201 | GTF2F1 | P35269 | General transcription factor IIF subunit 1 | chr19 | GO:0019903 | Not Cancer Driver | No | 47 | 0.0909090909090909 | 427 | 35 | 0.0676982591876208 | 0 |
| HSP90AA1-201 | HSP90AA1 | P07900 | Heat shock protein HSP 90-alpha | chr14 | GO:0019903 | Census, Compendium | Yes | 44 | 0.0601092896174863 | 258 | 15 | 0.0204918032786885 | 0 |
| HSP90B1-201 | HSP90B1 | P14625 | Endoplasmin | chr12 | GO:0019903 | Not Cancer Driver | No | 56 | 0.0697384806973848 | 269 | 17 | 0.0211706102117061 | 0 |
| IKBKE-203 | IKBKE | Q14164 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon | chr1 | GO:0019903 | Not Cancer Driver | No | 90 | 0.1256983240223463 | 76 | 10 | 0.0139664804469273 | 0 |
| IQGAP1-201 | IQGAP1 | P46940 | Ras GTPase-activating-like protein IQGAP1 | chr15 | GO:0019903 | Not Cancer Driver | No | 137 | 0.0826795413397706 | 351 | 25 | 0.0150875075437537 | 0 |
| IRS2-201 | IRS2 | Q9Y4H2 | Insulin receptor substrate 2 | chr13 | GO:0019903 | Not Cancer Driver | No | 44 | 0.0328849028400597 | 1117 | 34 | 0.0254110612855007 | 0 |
| ITGA1-201 | ITGA1 | P56199 | Integrin alpha-1 | chr5 | GO:0019903 | Not Cancer Driver | No | 106 | 0.0899067005937235 | 107 | 8 | 0.006785411365564 | 0 |
| JAK1-201 | JAK1 | P23458 | Tyrosine-protein kinase JAK1 | chr1 | GO:0019903 | Census, Compendium | Yes | 109 | 0.0944540727902946 | 120 | 6 | 0.0051993067590987 | 2 |
| JAK3-201 | JAK3 | P52333 | Tyrosine-protein kinase JAK3 | chr19 | GO:0019903 | Census, Compendium | Yes | 131 | 0.1165480427046263 | 63 | 4 | 0.0035587188612099 | 7 |
| JUP-203 | JUP | P14923 | Junction plakoglobin | chr17 | GO:0019903 | Not Cancer Driver | No | 81 | 0.1087248322147651 | 242 | 24 | 0.0322147651006711 | 0 |
| KAT2A-201 | KAT2A | Q92830 | Histone acetyltransferase KAT2A | chr17 | GO:0019903 | Not Cancer Driver | No | 70 | 0.08363201911589 | 251 | 11 | 0.013142174432497 | 0 |
| KCNN4-209 | KCNN4 | O15554 | Intermediate conductance calcium-activated potassium channel protein 4 | chr19 | GO:0019903 | Not Cancer Driver | No | 40 | 0.0936768149882904 | 31 | 2 | 0.0046838407494145 | 2 |
| KIF3A-202 | KIF3A | Q9Y496 | Kinesin-like protein KIF3A | chr5 | GO:0019903 | Not Cancer Driver | No | 49 | 0.0701001430615164 | 409 | 35 | 0.050071530758226 | 0 |
| KIFAP3-201 | KIFAP3 | Q92845 | Kinesin-associated protein 3 | chr1 | GO:0019903 | Not Cancer Driver | No | 89 | 0.1123737373737373 | 71 | 8 | 0.0101010101010101 | 0 |
| LCK-202 | LCK | P06239 | Tyrosine-protein kinase Lck | chr1 | GO:0019903 | Census | Yes | 76 | 0.1493123772102161 | 95 | 12 | 0.0235756385068762 | 1 |
| LGALS3-201 | LGALS3 | P17931 | Galectin-3 | chr14 | GO:0019903 | Not Cancer Driver | No | 9 | 0.036 | 133 | 0 | 0.0 | 0 |
| LILRB4-211 | LILRB4 | Q8NHJ6 | Leukocyte immunoglobulin-like receptor subfamily B member 4 | chr19 | GO:0019903 | Not Cancer Driver | No | 122 | 0.2723214285714285 | 276 | 88 | 0.1964285714285714 | 0 |
| MAP2K7-201 | MAP2K7 | O14733 | Dual specificity mitogen-activated protein kinase kinase 7 | chr19 | GO:0019903 | Compendium | Yes | 78 | 0.1861575178997613 | 145 | 17 | 0.0405727923627685 | 0 |
| MAP3K5-201 | MAP3K5 | Q99683 | Mitogen-activated protein kinase kinase kinase 5 | chr6 | GO:0019903 | Not Cancer Driver | No | 146 | 0.106259097525473 | 244 | 23 | 0.0167394468704512 | 0 |
| MAPK14-201 | MAPK14 | Q16539 | Mitogen-activated protein kinase 14 | chr6 | GO:0019903 | Not Cancer Driver | No | 22 | 0.0611111111111111 | 25 | 0 | 0.0 | 0 |
| MAPK8-206 | MAPK8 | P45983 | Mitogen-activated protein kinase 8 | chr10 | GO:0019903 | Not Cancer Driver | No | 52 | 0.1217798594847775 | 94 | 9 | 0.0210772833723653 | 0 |
| MET-202 | MET | P08581 | Hepatocyte growth factor receptor | chr7 | GO:0019903 | Census, Compendium | Yes | 161 | 0.1158273381294964 | 62 | 10 | 0.0071942446043165 | 16 |
| MTMR3-204 | MTMR3 | Q13615 | Myotubularin-related protein 3 | chr22 | GO:0019903 | Not Cancer Driver | No | 101 | 0.0843071786310517 | 501 | 48 | 0.0400667779632721 | 0 |
| MTMR4-201 | MTMR4 | Q9NYA4 | Myotubularin-related protein 4 | chr17 | GO:0019903 | Not Cancer Driver | No | 104 | 0.0870292887029288 | 476 | 43 | 0.0359832635983263 | 0 |
| MTMR9-201 | MTMR9 | Q96QG7 | Myotubularin-related protein 9 | chr8 | GO:0019903 | Not Cancer Driver | No | 38 | 0.0692167577413479 | 45 | 4 | 0.0072859744990892 | 0 |
| MVP-201 | MVP | Q14764 | Major vault protein | chr16 | GO:0019903 | Not Cancer Driver | No | 97 | 0.108622620380739 | 286 | 17 | 0.019036954087346 | 0 |
| MYO16-202 | MYO16 | Q9Y6X6 | Unconventional myosin-XVI | chr13 | GO:0019903 | Not Cancer Driver | No | 322 | 0.1733046286329386 | 688 | 89 | 0.0479009687836383 | 0 |
| NEK2-202 | NEK2 | P51955 | Serine/threonine-protein kinase Nek2 | chr1 | GO:0019903 | Not Cancer Driver | No | 44 | 0.098876404494382 | 93 | 12 | 0.0269662921348314 | 0 |
| PDLIM4-201 | PDLIM4 | P50479 | PDZ and LIM domain protein 4 | chr5 | GO:0019903 | Not Cancer Driver | No | 35 | 0.106060606060606 | 240 | 27 | 0.0818181818181818 | 0 |
| PIK3R1-211 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | GO:0019903 | Census, Compendium | Yes | 122 | 0.1685082872928177 | 271 | 50 | 0.0690607734806629 | 2 |
| PIK3R2-201 | PIK3R2 | O00459 | Phosphatidylinositol 3-kinase regulatory subunit beta | chr19 | GO:0019903 | Not Cancer Driver | No | 83 | 0.114010989010989 | 418 | 40 | 0.0549450549450549 | 3 |
| PPME1-201 | PPME1 | Q9Y570 | Protein phosphatase methylesterase 1 | chr11 | GO:0019903 | Not Cancer Driver | No | 28 | 0.0725388601036269 | 146 | 8 | 0.0207253886010362 | 0 |
| PPP1R3C-201 | PPP1R3C | Q9UQK1 | Protein phosphatase 1 regulatory subunit 3C | chr10 | GO:0019903 | Not Cancer Driver | No | 19 | 0.0599369085173501 | 16 | 0 | 0.0 | 0 |
| PPP1R3F-201 | PPP1R3F | Q6ZSY5 | Protein phosphatase 1 regulatory subunit 3F | chrX | GO:0019903 | Not Cancer Driver | No | 57 | 0.0713391739674593 | 637 | 44 | 0.0550688360450563 | 0 |
| PPP6R1-201 | PPP6R1 | Q9UPN7 | Serine/threonine-protein phosphatase 6 regulatory subunit 1 | chr19 | GO:0019903 | Not Cancer Driver | No | 60 | 0.0681044267877412 | 473 | 36 | 0.0408626560726447 | 0 |
| PPP6R2-201 | PPP6R2 | O75170 | Serine/threonine-protein phosphatase 6 regulatory subunit 2 | chr22 | GO:0019903 | Not Cancer Driver | No | 76 | 0.0786749482401656 | 496 | 48 | 0.0496894409937888 | 0 |
| PPP6R3-203 | PPP6R3 | Q5H9R7 | Serine/threonine-protein phosphatase 6 regulatory subunit 3 | chr11 | GO:0019903 | Not Cancer Driver | No | 77 | 0.0882016036655212 | 389 | 37 | 0.0423825887743413 | 0 |
| PTK2-228 | PTK2 | Q05397 | Focal adhesion kinase 1 | chr8 | GO:0019903 | Not Cancer Driver | No | 102 | 0.0969581749049429 | 426 | 45 | 0.0427756653992395 | 0 |
| PTPRT-203 | PTPRT | O14522 | Receptor-type tyrosine-protein phosphatase T | chr20 | GO:0019903 | Census, Compendium | Yes | 460 | 0.3192227619708536 | 298 | 104 | 0.0721721027064538 | 0 |
| PXN-201 | PXN | P49023 | Paxillin | chr12 | GO:0019903 | Not Cancer Driver | No | 41 | 0.0693739424703891 | 342 | 14 | 0.0236886632825719 | 0 |
| RACK1-227 | RACK1 | P63244 | Small ribosomal subunit protein RACK1 | chr5 | GO:0019903 | Not Cancer Driver | No | 27 | 0.085173501577287 | 13 | 0 | 0.0 | 0 |
| ROS1-202 | ROS1 | P08922 | Proto-oncogene tyrosine-protein kinase ROS | chr6 | GO:0019903 | Census | Yes | 356 | 0.1516829995739241 | 197 | 45 | 0.0191734128674904 | 0 |
| RPA2-203 | RPA2 | P15927 | Replication protein A 32 kDa subunit | chr1 | GO:0019903 | Not Cancer Driver | No | 20 | 0.074074074074074 | 117 | 12 | 0.0444444444444444 | 0 |
| SHOC2-202 | SHOC2 | Q9UQ13 | Leucine-rich repeat protein SHOC-2 | chr10 | GO:0019903 | Not Cancer Driver | No | 38 | 0.0652920962199312 | 110 | 9 | 0.0154639175257731 | 2 |
| SIRPA-202 | SIRPA | P78324 | Tyrosine-protein phosphatase non-receptor type substrate 1 | chr20 | GO:0019903 | Census, Compendium | Yes | 60 | 0.119047619047619 | 282 | 41 | 0.0813492063492063 | 0 |
| SKAP1-201 | SKAP1 | Q86WV1 | Src kinase-associated phosphoprotein 1 | chr17 | GO:0019903 | Not Cancer Driver | No | 58 | 0.1615598885793872 | 132 | 24 | 0.0668523676880222 | 0 |
| SNX3-201 | SNX3 | O60493 | Sorting nexin-3 | chr6 | GO:0019903 | Not Cancer Driver | No | 16 | 0.0987654320987654 | 37 | 3 | 0.0185185185185185 | 0 |
| STAT3-201 | STAT3 | P40763 | Signal transducer and activator of transcription 3 | chr17 | GO:0019903 | Census, Compendium | Yes | 93 | 0.1207792207792207 | 152 | 16 | 0.0207792207792207 | 15 |
| STAT6-201 | STAT6 | P42226 | Signal transducer and activator of transcription 6 | chr12 | GO:0019903 | Census, Compendium | Yes | 86 | 0.101534828807556 | 325 | 39 | 0.0460448642266824 | 0 |
| STX17-201 | STX17 | P56962 | Syntaxin-17 | chr9 | GO:0019903 | Not Cancer Driver | No | 24 | 0.0794701986754966 | 81 | 6 | 0.0198675496688741 | 0 |
| STYXL1-203 | STYXL1 | Q9Y6J8 | Serine/threonine/tyrosine-interacting-like protein 1 | chr7 | GO:0019903 | Not Cancer Driver | No | 43 | 0.1373801916932907 | 18 | 2 | 0.0063897763578274 | 0 |
| TBK1-201 | TBK1 | Q9UHD2 | Serine/threonine-protein kinase TBK1 | chr12 | GO:0019903 | Not Cancer Driver | No | 68 | 0.093278463648834 | 42 | 4 | 0.0054869684499314 | 12 |
| TRAF2-201 | TRAF2 | Q12933 | TNF receptor-associated factor 2 | chr9 | GO:0019903 | Not Cancer Driver | No | 51 | 0.1017964071856287 | 4 | 1 | 0.0019960079840319 | 0 |
| TRAF3-202 | TRAF3 | Q13114 | TNF receptor-associated factor 3 | chr14 | GO:0019903 | Compendium | Yes | 49 | 0.0862676056338028 | 101 | 8 | 0.0140845070422535 | 1 |
| VCP-201 | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | GO:0019903 | Not Cancer Driver | No | 74 | 0.0918114143920595 | 186 | 14 | 0.0173697270471464 | 12 |
| VRK3-201 | VRK3 | Q8IV63 | Inactive serine/threonine-protein kinase VRK3 | chr19 | GO:0019903 | Not Cancer Driver | No | 52 | 0.1097046413502109 | 182 | 12 | 0.0253164556962025 | 0 |
| YWHAE-201 | YWHAE | P62258 | 14-3-3 protein epsilon | chr17 | GO:0019903 | Census | Yes | 24 | 0.0941176470588235 | 41 | 1 | 0.0039215686274509 | 0 |