Total number of protein in "GO:0021766" GO term: 71
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALK-201 | ALK | Q9UM73 | ALK tyrosine kinase receptor | chr2 | GO:0021766 | Census, Compendium | Yes | 233 | 0.1438271604938271 | 577 | 79 | 0.0487654320987654 | 12 |
| ANXA3-201 | ANXA3 | P12429 | Annexin A3 | chr4 | GO:0021766 | Not Cancer Driver | No | 41 | 0.1269349845201238 | 22 | 3 | 0.0092879256965944 | 0 |
| ATG16L1-203 | ATG16L1 | Q676U5 | Autophagy-related protein 16-1 | chr2 | GO:0021766 | Not Cancer Driver | No | 54 | 0.0889621087314662 | 240 | 19 | 0.0313014827018121 | 1 |
| ATP2B4-203 | ATP2B4 | P23634 | Plasma membrane calcium-transporting ATPase 4 | chr1 | GO:0021766 | Not Cancer Driver | No | 113 | 0.0937759336099585 | 264 | 20 | 0.0165975103734439 | 0 |
| BBS1-201 | BBS1 | Q8NFJ9 | Bardet-Biedl syndrome 1 protein | chr11 | GO:0021766 | Not Cancer Driver | No | 52 | 0.087689713322091 | 100 | 9 | 0.0151770657672849 | 11 |
| BBS2-201 | BBS2 | Q9BXC9 | Bardet-Biedl syndrome 2 protein | chr16 | GO:0021766 | Not Cancer Driver | No | 60 | 0.0832177531206657 | 76 | 8 | 0.0110957004160887 | 20 |
| BBS4-201 | BBS4 | Q96RK4 | Bardet-Biedl syndrome 4 protein | chr15 | GO:0021766 | Not Cancer Driver | No | 44 | 0.0847784200385356 | 111 | 14 | 0.0269749518304431 | 9 |
| BCAN-201 | BCAN | Q96GW7 | Brevican core protein | chr1 | GO:0021766 | Not Cancer Driver | No | 167 | 0.1833150384193194 | 342 | 69 | 0.0757409440175631 | 0 |
| CASP3-201 | CASP3 | P42574 | Caspase-3 | chr4 | GO:0021766 | Census | Yes | 19 | 0.0685920577617328 | 64 | 1 | 0.003610108303249 | 0 |
| CDK5-204 | CDK5 | Q00535 | Cyclin-dependent kinase 5 | chr7 | GO:0021766 | Not Cancer Driver | No | 38 | 0.1301369863013698 | 5 | 0 | 0.0 | 0 |
| CDK5R1-201 | CDK5R1 | Q15078 | Cyclin-dependent kinase 5 activator 1 | chr17 | GO:0021766 | Not Cancer Driver | No | 29 | 0.0944625407166123 | 103 | 10 | 0.0325732899022801 | 0 |
| CDK5R2-201 | CDK5R2 | Q13319 | Cyclin-dependent kinase 5 activator 2 | chr2 | GO:0021766 | Not Cancer Driver | No | 10 | 0.0272479564032697 | 205 | 2 | 0.0054495912806539 | 0 |
| CRK-201 | CRK | P46108 | Adapter molecule crk | chr17 | GO:0021766 | Not Cancer Driver | No | 24 | 0.0789473684210526 | 197 | 19 | 0.0625 | 0 |
| CRKL-201 | CRKL | P46109 | Crk-like protein | chr22 | GO:0021766 | Not Cancer Driver | No | 24 | 0.0792079207920792 | 160 | 17 | 0.0561056105610561 | 0 |
| DAB1-203 | DAB1 | O75553 | Disabled homolog 1 | chr1 | GO:0021766 | Not Cancer Driver | No | 158 | 0.2687074829931973 | 393 | 111 | 0.1887755102040816 | 0 |
| DCLK2-201 | DCLK2 | Q8N568 | Serine/threonine-protein kinase DCLK2 | chr4 | GO:0021766 | Not Cancer Driver | No | 73 | 0.0953002610966057 | 260 | 19 | 0.0248041775456919 | 0 |
| DLX1-203 | DLX1 | P56177 | Homeobox protein DLX-1 | chr2 | GO:0021766 | Not Cancer Driver | No | 21 | 0.0823529411764705 | 183 | 17 | 0.0666666666666666 | 0 |
| DLX2-201 | DLX2 | Q07687 | Homeobox protein DLX-2 | chr2 | GO:0021766 | Not Cancer Driver | No | 33 | 0.1006097560975609 | 264 | 24 | 0.073170731707317 | 0 |
| EIF2B5-226 | EIF2B5 | Q13144 | Translation initiation factor eIF-2B subunit epsilon | chr3 | GO:0021766 | Not Cancer Driver | No | 49 | 0.0679611650485436 | 179 | 9 | 0.0124826629680998 | 21 |
| ENST00000419755 | BBS1 | Q8NFJ9 | Bardet-Biedl syndrome 1 protein | chr11 | GO:0021766 | Not Cancer Driver | No | 52 | 0.0825396825396825 | 132 | 7 | 0.0111111111111111 | 11 |
| EPHA5-201 | EPHA5 | P54756 | Ephrin type-A receptor 5 | chr4 | GO:0021766 | Not Cancer Driver | No | 296 | 0.2854387656702025 | 84 | 24 | 0.0231436837029893 | 0 |
| EZH1-202 | EZH1 | Q92800 | Histone-lysine N-methyltransferase EZH1 | chr17 | GO:0021766 | Not Cancer Driver | No | 60 | 0.0803212851405622 | 213 | 18 | 0.0240963855421686 | 0 |
| EZH2-203 | EZH2 | Q15910 | Histone-lysine N-methyltransferase EZH2 | chr7 | GO:0021766 | Census, Compendium | Yes | 74 | 0.099195710455764 | 284 | 32 | 0.0428954423592493 | 11 |
| FEZ1-201 | FEZ1 | Q99689 | Fasciculation and elongation protein zeta-1 | chr11 | GO:0021766 | Not Cancer Driver | No | 47 | 0.1198979591836734 | 278 | 37 | 0.0943877551020408 | 0 |
| FGF13-202 | FGF13 | Q92913 | Fibroblast growth factor 13 | chrX | GO:0021766 | Not Cancer Driver | No | 49 | 0.2 | 96 | 20 | 0.0816326530612244 | 3 |
| GLI3-201 | GLI3 | P10071 | Transcriptional activator GLI3 | chr7 | GO:0021766 | Not Cancer Driver | No | 308 | 0.1949367088607595 | 1362 | 270 | 0.170886075949367 | 7 |
| GSK3B-201 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | GO:0021766 | Not Cancer Driver | No | 34 | 0.0809523809523809 | 148 | 6 | 0.0142857142857142 | 0 |
| HDAC1-201 | HDAC1 | Q13547 | Histone deacetylase 1 | chr1 | GO:0021766 | Not Cancer Driver | No | 30 | 0.0622406639004149 | 135 | 5 | 0.0103734439834024 | 0 |
| HSD3B1-201 | HSD3B1 | P14060 | 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 | chr1 | GO:0021766 | Not Cancer Driver | No | 55 | 0.1474530831099195 | 25 | 2 | 0.0053619302949061 | 0 |
| HSD3B2-201 | HSD3B2 | P26439 | 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 | chr1 | GO:0021766 | Not Cancer Driver | No | 67 | 0.1801075268817204 | 24 | 7 | 0.0188172043010752 | 23 |
| HTR5A-201 | HTR5A | P47898 | 5-hydroxytryptamine receptor 5A | chr7 | GO:0021766 | Not Cancer Driver | No | 134 | 0.3753501400560224 | 6 | 1 | 0.0028011204481792 | 0 |
| ID4-201 | ID4 | P47928 | DNA-binding protein inhibitor ID-4 | chr6 | GO:0021766 | Not Cancer Driver | No | 5 | 0.031055900621118 | 72 | 1 | 0.0062111801242236 | 0 |
| IGF1R-217 | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | GO:0021766 | Not Cancer Driver | No | 143 | 0.1046086320409656 | 265 | 30 | 0.021945866861741 | 6 |
| KCNA1-201 | KCNA1 | Q09470 | Potassium voltage-gated channel subfamily A member 1 | chr12 | GO:0021766 | Not Cancer Driver | No | 139 | 0.2808080808080808 | 69 | 29 | 0.0585858585858585 | 17 |
| KDM6B-202 | KDM6B | O15054 | Lysine-specific demethylase 6B | chr17 | GO:0021766 | Not Cancer Driver | No | 151 | 0.0919050517346317 | 1288 | 116 | 0.0706025562994522 | 2 |
| KIF14-201 | KIF14 | Q15058 | Kinesin-like protein KIF14 | chr1 | GO:0021766 | Not Cancer Driver | No | 145 | 0.0879854368932038 | 777 | 65 | 0.0394417475728155 | 2 |
| KIRREL3-201 | KIRREL3 | Q8IZU9 | Kin of IRRE-like protein 3 | chr11 | GO:0021766 | Not Cancer Driver | No | 84 | 0.1079691516709511 | 223 | 23 | 0.0295629820051413 | 0 |
| LHX5-201 | LHX5 | Q9H2C1 | LIM/homeobox protein Lhx5 | chr12 | GO:0021766 | Not Cancer Driver | No | 36 | 0.0895522388059701 | 253 | 19 | 0.0472636815920398 | 0 |
| MAS1-202 | MAS1 | P04201 | Proto-oncogene Mas | chr6 | GO:0021766 | Not Cancer Driver | No | 36 | 0.1107692307692307 | 5 | 2 | 0.0061538461538461 | 0 |
| MECP2-201 | MECP2 | P51608 | Methyl-CpG-binding protein 2 | chrX | GO:0021766 | Not Cancer Driver | No | 44 | 0.0905349794238683 | 482 | 43 | 0.088477366255144 | 32 |
| MFSD2A-201 | MFSD2A | Q8NA29 | Sodium-dependent lysophosphatidylcholine symporter 1 | chr1 | GO:0021766 | Not Cancer Driver | No | 37 | 0.0681399631675874 | 36 | 3 | 0.005524861878453 | 7 |
| MKKS-201 | MKKS | Q9NPJ1 | Molecular chaperone MKKS | chr20 | GO:0021766 | Not Cancer Driver | No | 35 | 0.0614035087719298 | 7 | 0 | 0.0 | 22 |
| NCOA1-202 | NCOA1 | Q15788 | Nuclear receptor coactivator 1 | chr2 | GO:0021766 | Census, Compendium | Yes | 135 | 0.0936849410131853 | 1217 | 107 | 0.0742539902845246 | 0 |
| NEFL-201 | NEFL | P07196 | Neurofilament light polypeptide | chr8 | GO:0021766 | Not Cancer Driver | No | 0 | 0.0 | 285 | 0 | 0.0 | 10 |
| NF2-202 | NF2 | P35240 | Merlin | chr22 | GO:0021766 | Census, Compendium | Yes | 49 | 0.0823529411764705 | 252 | 18 | 0.0302521008403361 | 16 |
| NKX2-1-203 | NKX2-1 | P43699 | Homeobox protein Nkx-2.1 | chr14 | GO:0021766 | Census, Compendium | Yes | 34 | 0.091644204851752 | 336 | 32 | 0.0862533692722372 | 6 |
| OGDH-201 | OGDH | Q02218 | 2-oxoglutarate dehydrogenase complex component E1 | chr7 | GO:0021766 | Not Cancer Driver | No | 120 | 0.1173020527859237 | 106 | 18 | 0.0175953079178885 | 0 |
| PAFAH1B1-202 | PAFAH1B1 | P43034 | Platelet-activating factor acetylhydrolase IB subunit beta | chr17 | GO:0021766 | Not Cancer Driver | No | 37 | 0.0902439024390243 | 83 | 11 | 0.0268292682926829 | 7 |
| PHLPP2-206 | PHLPP2 | Q6ZVD8 | PH domain leucine-rich repeat-containing protein phosphatase 2 | chr16 | GO:0021766 | Not Cancer Driver | No | 109 | 0.0823885109599395 | 310 | 27 | 0.0204081632653061 | 0 |
| PLXNA3-201 | PLXNA3 | P51805 | Plexin-A3 | chrX | GO:0021766 | Not Cancer Driver | No | 198 | 0.1058257616247995 | 199 | 33 | 0.0176376269374665 | 0 |
| PPP1R9B-202 | PPP1R9B | Q96SB3 | Neurabin-2 | chr17 | GO:0021766 | Not Cancer Driver | No | 37 | 0.0452876376988984 | 698 | 27 | 0.033047735618115 | 0 |
| PTPRS-201 | PTPRS | Q13332 | Receptor-type tyrosine-protein phosphatase S | chr19 | GO:0021766 | Not Cancer Driver | No | 191 | 0.0980492813141683 | 834 | 88 | 0.0451745379876796 | 0 |
| RAN-212 | RAN | P62826 | GTP-binding nuclear protein Ran | chr12 | GO:0021766 | Not Cancer Driver | No | 18 | 0.0833333333333333 | 14 | 0 | 0.0 | 0 |
| RARA-201 | RARA | P10276 | Retinoic acid receptor alpha | chr17 | GO:0021766 | Census, Compendium | Yes | 60 | 0.1298701298701298 | 167 | 14 | 0.0303030303030303 | 0 |
| RELN-203 | RELN | P78509 | Reelin | chr7 | GO:0021766 | Not Cancer Driver | No | 626 | 0.1809248554913294 | 108 | 13 | 0.003757225433526 | 7 |
| SCT-201 | SCT | P09683 | Secretin | chr11 | GO:0021766 | Not Cancer Driver | No | 4 | 0.0330578512396694 | 71 | 3 | 0.024793388429752 | 0 |
| SEMA6B-201 | SEMA6B | Q9H3T3 | Semaphorin-6B | chr19 | GO:0021766 | Not Cancer Driver | No | 66 | 0.0743243243243243 | 340 | 17 | 0.0191441441441441 | 0 |
| SLC32A1-201 | SLC32A1 | Q9H598 | Vesicular inhibitory amino acid transporter | chr20 | GO:0021766 | Not Cancer Driver | No | 108 | 0.2057142857142857 | 82 | 15 | 0.0285714285714285 | 0 |
| SRD5A1-201 | SRD5A1 | P18405 | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | chr5 | GO:0021766 | Not Cancer Driver | No | 26 | 0.1003861003861003 | 0 | 0 | 0.0 | 0 |
| SRD5A2-201 | SRD5A2 | P31213 | 3-oxo-5-alpha-steroid 4-dehydrogenase 2 | chr2 | GO:0021766 | Not Cancer Driver | No | 0 | 0.0 | 0 | 0 | 0.0 | 20 |
| SRF-201 | SRF | P11831 | Serum response factor | chr6 | GO:0021766 | Not Cancer Driver | No | 30 | 0.0590551181102362 | 443 | 29 | 0.0570866141732283 | 0 |
| TSC1-201 | TSC1 | Q92574 | Hamartin | chr9 | GO:0021766 | Census, Compendium | Yes | 94 | 0.0807560137457044 | 735 | 53 | 0.0455326460481099 | 11 |
| TSKU-201 | TSKU | Q8WUA8 | Tsukushi | chr11 | GO:0021766 | Not Cancer Driver | No | 41 | 0.1161473087818696 | 44 | 5 | 0.0141643059490084 | 0 |
| UBA6-201 | UBA6 | A0AVT1 | Ubiquitin-like modifier-activating enzyme 6 | chr4 | GO:0021766 | Not Cancer Driver | No | 106 | 0.1007604562737642 | 90 | 7 | 0.0066539923954372 | 0 |
| UQCRQ-203 | UQCRQ | O14949 | Cytochrome b-c1 complex subunit 8 | chr5 | GO:0021766 | Not Cancer Driver | No | 8 | 0.0975609756097561 | 12 | 1 | 0.0121951219512195 | 1 |
| WNT3A-201 | WNT3A | P56704 | Protein Wnt-3a | chr1 | GO:0021766 | Not Cancer Driver | No | 60 | 0.1704545454545454 | 37 | 2 | 0.0056818181818181 | 0 |
| XRCC1-201 | XRCC1 | P18887 | DNA repair protein XRCC1 | chr19 | GO:0021766 | Not Cancer Driver | No | 58 | 0.0916271721958925 | 431 | 39 | 0.0616113744075829 | 1 |
| XRN2-201 | XRN2 | Q9H0D6 | 5'-3' exoribonuclease 2 | chr20 | GO:0021766 | Not Cancer Driver | No | 91 | 0.0957894736842105 | 428 | 48 | 0.0505263157894736 | 0 |
| YWHAE-201 | YWHAE | P62258 | 14-3-3 protein epsilon | chr17 | GO:0021766 | Census | Yes | 24 | 0.0941176470588235 | 41 | 1 | 0.0039215686274509 | 0 |
| ZIC1-201 | ZIC1 | Q15915 | Zinc finger protein ZIC 1 | chr3 | GO:0021766 | Not Cancer Driver | No | 172 | 0.3847874720357941 | 246 | 102 | 0.2281879194630872 | 1 |
| ZIC3-201 | ZIC3 | O60481 | Zinc finger protein ZIC 3 | chrX | GO:0021766 | Not Cancer Driver | No | 69 | 0.1477516059957173 | 327 | 47 | 0.1006423982869379 | 10 |